idoxuridine has been researched along with Cancer of Head in 26 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty patients with squamous cell carcinomas of the head and neck treated with primary surgery were injected with pimonidazole and IdUrd the evening before operation." | 5.31 | HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors. ( Balm, AJ; Begg, AC; Blijweert, E; Blommestijn, G; Delaere, P; Haustermans, KM; Hoebers, FJ; Hofland, I; Janssen, HL; Raleigh, JA; Sciot, R; Semenza, GL; Sprong, D; van Velthuysen, ML; Varia, MA, 2002) |
| "Much of the early clinical work in head and neck cancer involved treatment of patients with advanced, recurrent disease who had not responded to conventional therapy." | 2.38 | Sensitizers of photoradiation and ionizing radiation in the management of head and neck cancer. ( DeLaney, TF; Lebovics, RS, 1993) |
| "Twenty patients with squamous cell carcinomas of the head and neck treated with primary surgery were injected with pimonidazole and IdUrd the evening before operation." | 1.31 | HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors. ( Balm, AJ; Begg, AC; Blijweert, E; Blommestijn, G; Delaere, P; Haustermans, KM; Hoebers, FJ; Hofland, I; Janssen, HL; Raleigh, JA; Sciot, R; Semenza, GL; Sprong, D; van Velthuysen, ML; Varia, MA, 2002) |
| "33 patients with head and neck cancer were administered iododeoxyuridine (IdUrd) prior to treatment and a second administration of bromodeoxyuridine (BrdUrd) prior to the fifth fraction of 2 Gy." | 1.31 | Cell kinetic changes in human squamous cell carcinomas during radiotherapy studied using the in vivo administration of two halogenated pyrimidines. ( Flygare, P; Gustafsson, H; Sjöström, B; Wilson, GD; Zackrisson, B, 2002) |
| "Head and neck neoplasms may also be suitable for halogenated pyrimidine-mediated sensitization; previous regimens using intra-arterial BrdUrd delivery, however, were poorly tolerated." | 1.29 | Treatment of locally advanced cancer of the head and neck with 5'-iododeoxyuridine and hyperfractionated radiation therapy: measurement of cell labeling and thymidine replacement. ( Cook, JA; Epstein, AH; Fuetsch, ES; Glatstein, E; Goffman, T; Lebovics, RS; Okunieff, P; Teague, D, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (11.54) | 18.7374 |
| 1990's | 14 (53.85) | 18.2507 |
| 2000's | 9 (34.62) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Janssen, HL | 1 |
| Haustermans, KM | 1 |
| Sprong, D | 2 |
| Blommestijn, G | 2 |
| Hofland, I | 4 |
| Hoebers, FJ | 1 |
| Blijweert, E | 1 |
| Raleigh, JA | 2 |
| Semenza, GL | 1 |
| Varia, MA | 1 |
| Balm, AJ | 1 |
| van Velthuysen, ML | 1 |
| Delaere, P | 2 |
| Sciot, R | 2 |
| Begg, AC | 6 |
| Harrington, KJ | 1 |
| Syrigos, KN | 1 |
| Uster, PS | 1 |
| Zetter, A | 1 |
| Lewanski, CR | 1 |
| Gullick, WJ | 1 |
| Vile, RG | 1 |
| Stewart, JS | 1 |
| Corde, S | 1 |
| Joubert, A | 1 |
| Adam, JF | 1 |
| Charvet, AM | 1 |
| Le Bas, JF | 1 |
| Estève, F | 1 |
| Elleaume, H | 1 |
| Balosso, J | 1 |
| Hoogsteen, IJ | 1 |
| Marres, HA | 2 |
| Wijffels, KI | 2 |
| Rijken, PF | 2 |
| Peters, JP | 2 |
| van den Hoogen, FJ | 1 |
| Oosterwijk, E | 1 |
| van der Kogel, AJ | 2 |
| Kaanders, JH | 2 |
| Kinsella, TJ | 1 |
| Mitchell, JB | 2 |
| Russo, A | 1 |
| Morstyn, G | 1 |
| Glatstein, E | 4 |
| Kotelnikov, VM | 2 |
| Coon, JS | 2 |
| Taylor, S | 1 |
| Hutchinson, J | 2 |
| Panje, W | 2 |
| Caldarelli, DD | 2 |
| LaFollette, S | 1 |
| Preisler, HD | 3 |
| Perez, LA | 1 |
| Dombkowski, D | 1 |
| Efird, J | 1 |
| Preffer, F | 1 |
| Suit, HD | 1 |
| Epstein, AH | 3 |
| Lebovics, RS | 3 |
| Goffman, T | 2 |
| Teague, D | 1 |
| Fuetsch, ES | 1 |
| Okunieff, P | 2 |
| Cook, JA | 4 |
| DeLaney, TF | 2 |
| Høyer, M | 1 |
| Jørgensen, K | 1 |
| Bundgaard, T | 1 |
| Johansen, LV | 1 |
| Bentzen, SM | 1 |
| Overgaard, M | 1 |
| Hansen, O | 1 |
| Søgaard, H | 1 |
| Overgaard, J | 2 |
| Sondak, VK | 1 |
| Robertson, JM | 1 |
| Sussman, JJ | 1 |
| Saran, PA | 1 |
| Chang, AE | 1 |
| Lawrence, TS | 1 |
| Van Waes, C | 1 |
| Smith, J | 1 |
| Kotelnikov, V | 1 |
| Cass, L | 1 |
| Spaulding, D | 1 |
| Coon JS, IV | 1 |
| Haleem, A | 1 |
| Taylor S, IV | 1 |
| Griem, K | 1 |
| Haustermans, K | 2 |
| Hart, AA | 1 |
| Dische, S | 1 |
| Saunders, M | 1 |
| Zackrisson, B | 2 |
| Gustaffson, H | 1 |
| Coucke, P | 1 |
| Paschoud, N | 1 |
| Hoyer, M | 1 |
| Antognoni, P | 1 |
| Richetti, A | 1 |
| Bourhis, J | 1 |
| Bartelink, H | 3 |
| Horiot, JC | 1 |
| Corvo, R | 1 |
| Giaretti, W | 1 |
| Awwad, H | 1 |
| Shouman, T | 2 |
| Jouffroy, T | 1 |
| Maciorowski, Z | 1 |
| Dobrowsky, W | 1 |
| Struikmans, H | 1 |
| Wilson, GD | 3 |
| Lotayef, M | 1 |
| Daley, FM | 1 |
| Awwad, HK | 1 |
| Fowler, JF | 1 |
| Janssen, H | 1 |
| Varia, M | 1 |
| Balm, A | 1 |
| Van Velthuyzen, L | 1 |
| Flygare, P | 1 |
| Gustafsson, H | 1 |
| Sjöström, B | 1 |
| Glass, J | 1 |
| Lebovics, R | 1 |
| Bobo, H | 1 |
| Pass, H | 1 |
| Oldfield, EH | 1 |
| Goffman, TE | 1 |
| Moonen, L | 2 |
| Schraub, S | 1 |
| Bontemps, P | 1 |
| Le Fur, R | 1 |
| Van Den Bogaert, W | 1 |
| Caspers, R | 1 |
| Van Glabbeke, M | 1 |
| Dessing, M | 1 |
| Goffinet, DR | 1 |
| Bagshaw, MA | 1 |
3 reviews available for idoxuridine and Cancer of Head
| Article | Year |
|---|---|
The clinical status of Tpot as a predictor? Or why no tempest in the Tpot!
Topics: Bromodeoxyuridine; Cell Division; Female; Head and Neck Neoplasms; Humans; Idoxuridine; Kinetics; Pr | 1995 |
Sensitizers of photoradiation and ionizing radiation in the management of head and neck cancer.
Topics: Head and Neck Neoplasms; Hematoporphyrin Photoradiation; Humans; Idoxuridine; Photosensitizing Agent | 1993 |
Clinical use of radiation sensitizing agents.
Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Bromodeoxycytidine; Bromodeoxyuridine; Bromoura | 1974 |
7 trials available for idoxuridine and Cancer of Head
| Article | Year |
|---|---|
The use of halogenated thymidine analogs as clinical radiosensitizers: rationale, current status, and future prospects: non-hypoxic cell sensitizers.
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Cell Survival; Clinical Trials as Topic; Combined Modal | 1984 |
Preoperative idoxuridine and radiation for large soft tissue sarcomas: clinical results with five-year follow-up.
Topics: Adolescent; Adult; Aged; Antimetabolites; Cause of Death; Chi-Square Distribution; Cohort Studies; D | 1998 |
Intravenous delivery of 5'-iododeoxyuridine during hyperfractionated radiotherapy for locally advanced head and neck cancers: results of a pilot study.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Disease-Free Survival; Dose Fracti | 1998 |
Aberrant expression of cyclin A in head and neck cancer.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Cycle; Combined Modality Therapy; Cyclin A; Female; Gene | 2000 |
Hypoxia and perfusion measurements in human tumors--initial experience with pimonidazole and IUdR.
Topics: Antibodies; Biopsy; Diffusion; Esophageal Neoplasms; Female; Head and Neck Neoplasms; Humans; Hypoxi | 2001 |
Tumour radiosensitization with the halogenated pyrimidines 5'-bromo- and 5'-iododeoxyuridine.
Topics: Brain Neoplasms; Bromodeoxyuridine; Glioma; Head and Neck Neoplasms; Humans; Idoxuridine; Radiation- | 1992 |
The predictive value of cell kinetic measurements in a European trial of accelerated fractionation in advanced head and neck tumors: an interim report.
Topics: Cell Division; DNA, Neoplasm; Head and Neck Neoplasms; Humans; Idoxuridine; Radiotherapy Dosage | 1990 |
16 other studies available for idoxuridine and Cancer of Head
| Article | Year |
|---|---|
HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors.
Topics: Carcinoma, Squamous Cell; Dimerization; Dose-Response Relationship, Drug; Head and Neck Neoplasms; H | 2002 |
Targeted radiosensitisation by pegylated liposome-encapsulated 3', 5'-O-dipalmitoyl 5-iodo-2'-deoxyuridine in a head and neck cancer xenograft model.
Topics: Animals; Carcinoma, Squamous Cell; Dose-Response Relationship, Radiation; Drug Carriers; Female; Hea | 2004 |
Synchrotron radiation-based experimental determination of the optimal energy for cell radiotoxicity enhancement following photoelectric effect on stable iodinated compounds.
Topics: Carcinoma, Squamous Cell; Cell Death; Cell Survival; Contrast Media; Head and Neck Neoplasms; Humans | 2004 |
Colocalization of carbonic anhydrase 9 expression and cell proliferation in human head and neck squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Biopsy; Carbonic Anhydrase IX; Carbonic Anhydras | 2005 |
Tumour cell proliferation under hypoxic conditions in human head and neck squamous cell carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Biopsy; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Proliferation; | 2008 |
In vivo labelling with halogenated pyrimidines of squamous cell carcinomas and adjacent non-involved mucosa of head and neck region.
Topics: Biomarkers, Tumor; Biopsy; Bromodeoxyuridine; Carcinoma, Squamous Cell; Epithelial Cells; Head and N | 1995 |
Cell proliferation kinetics in human tumor xenografts measured with iododeoxyuridine labeling and flow cytometry: a study of heterogeneity and a comparison between different methods of calculation and other proliferation measurements.
Topics: Animals; Carcinoma, Squamous Cell; Cell Count; Cell Division; Colorectal Neoplasms; DNA, Neoplasm; F | 1995 |
Treatment of locally advanced cancer of the head and neck with 5'-iododeoxyuridine and hyperfractionated radiation therapy: measurement of cell labeling and thymidine replacement.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Combined Modality Therapy; Female; Flow Cytometry | 1994 |
Lack of predictive value of potential doubling time and iododeoxyuridine labelling index in radiotherapy of squamous cell carcinoma of the head and neck.
Topics: Analysis of Variance; Carcinoma, Squamous Cell; Cell Cycle; Cell Division; DNA, Neoplasm; Head and N | 1998 |
Accuracy of histone H3 messenger RNA in situ hybridization for the assessment of cell proliferation in human tissues.
Topics: Biopsy; Carcinoma, Squamous Cell; Cell Division; Head and Neck Neoplasms; Histones; Humans; Idoxurid | 1997 |
Cell kinetics of head and neck cancers.
Topics: Biopsy; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Cycle; Cell Division; DNA, Neoplasm; G2 Ph | 1995 |
The value of pretreatment cell kinetic parameters as predictors for radiotherapy outcome in head and neck cancer: a multicenter analysis.
Topics: Analysis of Variance; Antimetabolites; Bromodeoxyuridine; Cell Cycle; Cell Division; DNA; Female; Fl | 1999 |
Is there a future for cell kinetic measurements using IdUrd or BdUrd?
Topics: Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Division; DNA, Neoplasm; Esophageal Neoplasms; Fol | 2001 |
Cell kinetic changes in human squamous cell carcinomas during radiotherapy studied using the in vivo administration of two halogenated pyrimidines.
Topics: Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Cycle; Cell Division; Feasibility Studies; Female; | 2002 |
Measurement of thymidine replacement in patients with high grade gliomas, head and neck tumors, and high grade sarcomas after continuous intravenous infusions of 5-iododeoxyuridine.
Topics: Animals; Cell Line; Combined Modality Therapy; DNA, Neoplasm; Flow Cytometry; Glioma; Head and Neck | 1992 |
Human tumour cell kinetics using a monoclonal antibody against iododeoxyuridine: intratumour sampling variations.
Topics: Antibodies, Monoclonal; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Cycle; DNA, Neo | 1988 |