Page last updated: 2024-11-07

idoxuridine and Breast Neoplasms

idoxuridine has been researched along with Breast Neoplasms in 16 studies

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"This study uses a three-dimensional cell culture model to investigate lethal bystander effects in human breast cancer cell cultures (MCF-7, MDA-MB-231) treated with (125)I-labeled 5-iodo-2 -deoxyuridine ((125)IdU)."3.78Induction of lethal bystander effects in human breast cancer cell cultures by DNA-incorporated Iodine-125 depends on phenotype. ( Akudugu, JM; Azzam, EI; Howell, RW, 2012)
" We have compared the cytotoxicity in human MCF-7 breast cancer cells of 125IUdR, 125I-iodotamoxifen, a nonsteroidal antiestrogen that is translocated from the cytoplasm to the nucleus of receptor containing cells, and 125I-iodoantipyrine, a biological indicator of the body water space."3.66Estrogen receptor-mediated cytotoxicity using iodine-125. ( Adelstein, SJ; Bloomer, WD; McLaughlin, WH; Milius, RA; Weichselbaum, RR, 1983)
"However, as the S-phase fraction in breast cancer is generally low, the variation between the different measurements is too large; therefore, the S-phase fraction is not a suitable indicator of response to treatment."1.29Iododeoxyuridine labelling of S-phase fraction in fine needle aspirates from breast carcinomas. ( Breedijk, AJ; Bruning, PF; Maas, RA; Peterse, JL, 1996)
" This method was applied to the study of the hormone-sensitivity of breast tumours, some of which showed a dose-response to 17 beta-estradiol."1.26Quantitative organ culture: an approach to prediction of tumour response. ( Krishnaswamy, A; Masters, JR; O'Donoghue, EP; Rigby, CC, 1980)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19908 (50.00)18.7374
1990's4 (25.00)18.2507
2000's2 (12.50)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vande Voorde, J1
Gago, F1
Vrancken, K1
Liekens, S1
Balzarini, J1
Akudugu, JM1
Azzam, EI1
Howell, RW1
ROTENBERG, AD1
BRUCE, WR1
BAKER, RG1
Bloomer, WD1
McLaughlin, WH1
Milius, RA1
Weichselbaum, RR1
Adelstein, SJ1
Masters, JR1
Krishnaswamy, A1
Rigby, CC1
O'Donoghue, EP1
Holmes, JM1
Mariani, G1
Collecchi, P1
Giuliani, L1
Baranowska-Kortylewicz, J1
Di Luca, L1
Meucci, G1
Viacava, P1
Van den Abbeele, AD1
Salvadori, PA1
Di Sacco, S1
Maas, RA1
Bruning, PF1
Breedijk, AJ1
Peterse, JL1
Yasui, L1
Hughes, A2
DeSombre, E1
Yasui, LS1
Desombre, ER1
Miller, MA1
Bokhari, SA1
Qadir, K1
Raza, A1
Santos, O1
Pant, KD1
Blank, EW1
Ceriani, RL1
Holder, WD1
Robey, WG1
Vande Woude, GF1
Oldham, RK2
Siwarski, D1
McCoy, JL1
Plata, EJ1
Herberman, RB2
Andrysek, O1
Altenbrunn, HJ1

Other Studies

16 other studies available for idoxuridine and Breast Neoplasms

ArticleYear
Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues.
    The Biochemical journal, 2012, Jul-01, Volume: 445, Issue:1

    Topics: Amino Acid Sequence; Antiviral Agents; Breast Neoplasms; Bromodeoxyuridine; Computational Biology; F

2012
Induction of lethal bystander effects in human breast cancer cell cultures by DNA-incorporated Iodine-125 depends on phenotype.
    International journal of radiation biology, 2012, Volume: 88, Issue:12

    Topics: Animals; Breast Neoplasms; Bystander Effect; Cell Death; Cell Survival; Deoxyuridine; DNA; Humans; I

2012
Incorporation of 5-iododeoxyuridine 1311 in spontaneous C3H mouse mammary tumours.
    The British journal of radiology, 1962, Volume: 35

    Topics: Animals; Breast Neoplasms; Humans; Idoxuridine; Iodine; Iodine Radioisotopes; Mice; Mice, Inbred C3H

1962
Estrogen receptor-mediated cytotoxicity using iodine-125.
    Journal of cellular biochemistry, 1983, Volume: 21, Issue:1

    Topics: Antipyrine; Breast Neoplasms; Cell Line; Cell Survival; Humans; Idoxuridine; Iodine Radioisotopes; R

1983
Quantitative organ culture: an approach to prediction of tumour response.
    The British journal of cancer. Supplement, 1980, Volume: 4

    Topics: Breast Neoplasms; DNA, Neoplasm; Dose-Response Relationship, Drug; Estradiol; Female; Humans; Idoxur

1980
The toxicity of 125I-5-iodo-2'-deoxyuridine (125IUdR) to canine tissue culture cells in vitro.
    Journal of comparative pathology, 1982, Volume: 92, Issue:3

    Topics: Animals; Breast Neoplasms; Cell Line; Cells; Culture Techniques; Dogs; Female; Horses; Humans; Idoxu

1982
Tumor targeting potential and metabolism of 5-[125I]iodo-2'-deoxyuridine injected intratumorally in patients with breast cancer.
    Annals of the New York Academy of Sciences, 1993, Nov-30, Volume: 698

    Topics: Aged; Aged, 80 and over; Autoradiography; Breast Neoplasms; Female; Humans; Idoxuridine; Iodine Radi

1993
Iododeoxyuridine labelling of S-phase fraction in fine needle aspirates from breast carcinomas.
    Journal of clinical pathology, 1996, Volume: 49, Issue:7

    Topics: Biopsy, Needle; Breast Neoplasms; DNA Replication; Female; Frozen Sections; Humans; Idoxuridine; Imm

1996
Relative biological effectiveness of accumulated 125IdU and 125I-estrogen decays in estrogen receptor-expressing MCF-7 human breast cancer cells.
    Radiation research, 2001, Volume: 155, Issue:2

    Topics: Adenocarcinoma; Breast Neoplasms; Cell Nucleus; Cell Survival; DNA Damage; DNA, Neoplasm; Dose-Respo

2001
Cytotoxicity of 125I-oestrogen decay in non-oestrogen receptor-expressing human breast cancer cells, MDA-231 and oestrogen receptor-expressing MCF-7 cells.
    International journal of radiation biology, 2001, Volume: 77, Issue:9

    Topics: Breast Neoplasms; Cell Survival; Estrogens; Female; Gamma Rays; Humans; Idoxuridine; Iodine Radioiso

2001
Simultaneous assessment of TGFB and cell cycle kinetics using IUdR/BrdU infusions in human neoplasms from plastic-embedded tissue.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1992, Volume: 40, Issue:3

    Topics: Antibodies, Monoclonal; Biopsy; Bone Marrow; Breast Neoplasms; Bromodeoxyuridine; Cell Cycle; Coloni

1992
5-Iododeoxyuridine increases the efficacy of the radioimmunotherapy of human tumors growing in nude mice.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1992, Volume: 33, Issue:8

    Topics: Animals; Aspartic Acid; Breast Neoplasms; Deoxycytidine; Drug Therapy, Combination; Humans; Idoxurid

1992
Activation of a C-type virus from the human carcinoma cell line HBT-3 by iododeoxyuridine and testosterone.
    Nature, 1974, Jun-21, Volume: 249, Issue:459

    Topics: Breast Neoplasms; Carcinoma; Clone Cells; Female; Humans; Idoxuridine; Microscopy, Phase-Contrast; R

1974
Evaluation of a cell-mediated cytotoxicity assay utilizing 125 iododeoxyuridine-labeled tissue-culture target cells.
    National Cancer Institute monograph, 1973, Volume: 37

    Topics: Adult; AKR murine leukemia virus; Animals; Antigens, Neoplasm; Breast Neoplasms; Cell Line; Cells, C

1973
Evaluation of cell-mediated cytotoxic reactivity against tumor associated antigens with 125I-iododeoxyuridine labeled target cells.
    Journal of immunology (Baltimore, Md. : 1950), 1973, Volume: 111, Issue:6

    Topics: AKR murine leukemia virus; Animals; Antigen-Antibody Reactions; Antigens, Neoplasm; Breast Neoplasms

1973
[The concentration of various radioactive preparations in the tumor and in other organs of the body].
    Nuclear-Medizin, 1965, Volume: 2

    Topics: Animals; Breast Neoplasms; Diagnosis, Differential; Female; Humans; Idoxuridine; Intestine, Small; I

1965