idoxuridine has been researched along with Brain Neoplasms in 49 studies
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| ") injection of radio-iododeoxyuridine (IdUrd), a thymidine (dThd) analogue, is envisaged for targeted Auger electron- or beta-radiation therapy of glioblastoma." | 7.72 | Highly efficient DNA incorporation of intratumourally injected [125I]iododeoxyuridine under thymidine synthesis blocking in human glioblastoma xenografts. ( Adamer, F; Buchegger, F; de Tribolet, N; Delaloye, AB; Dupertuis, YM; Grannavel, C; Kosinski, M; Mach, JP; Schaffland, AO, 2004) |
| " The killing of cells and apparent beneficial effect of tritiated thymidine in human leukemia are described." | 4.76 | Are there unexploited possibilities for the therapeutic use of radioactive and stable isotopically labeled DNA precursors and extracorporeal irradiation of the blood in treatment of leukemia? ( Cronkite, EP; Fairchild, RG; Miller, ME, 1983) |
| " Two complimentary SSR approaches have been successfully developed in the past 5 years in our team, and may be promising in high-grade glioma management: iodine-enhanced SSR, with an iodinated contrast agent; and Pt-enhanced SSR; a concomitant radio-chemotherapy treatment with locoregional injection of platinated chemotherapy drugs." | 3.74 | Heavy element enhanced synchrotron stereotactic radiotherapy as a promising brain tumour treatment. ( Adam, JF; Balosso, J; Biston, MC; Boudou, C; Charvet, AM; Elleaume, H; Estève, F; Rousseau, J, 2008) |
| ") injection of radio-iododeoxyuridine (IdUrd), a thymidine (dThd) analogue, is envisaged for targeted Auger electron- or beta-radiation therapy of glioblastoma." | 3.72 | Highly efficient DNA incorporation of intratumourally injected [125I]iododeoxyuridine under thymidine synthesis blocking in human glioblastoma xenografts. ( Adamer, F; Buchegger, F; de Tribolet, N; Delaloye, AB; Dupertuis, YM; Grannavel, C; Kosinski, M; Mach, JP; Schaffland, AO, 2004) |
| "Nineteen patients with human brain tumors (9 gliomas, 6 metastatic brain tumors, 3 meningiomas, 1 neurinoma) received intravenous infusions of iododeoxyuridine (IUdR) and bromodeoxyuridine (BUdR) at different time sequences, to estimate the duration of S-phase (Ts) and the potential doubling time (Tp) of individual tumors." | 3.68 | [Proliferation kinetics of human brain tumors by in situ double labeling with bromodeoxyuridine and iododeoxyuridine]. ( Hoshino, T; Maeda, T, 1992) |
| "Fifty-seven patients with brain tumors (29 gliomas, 23 meningiomas, 5 miscellaneous) received infusions of intravenous iododeoxyuridine (IUdR) and bromodeoxyuridine (BUdR) 1-5 hr apart shortly before tumor removal." | 3.68 | Cell kinetic analysis of human brain tumors by in situ double labelling with bromodeoxyuridine and iododeoxyuridine. ( Asai, A; Davis, RL; Dodson, BA; Hoshino, T; Ito, S; Prados, MD; Shibuya, M; Wilson, CB, 1992) |
| "Twenty-one patients had Grade 3 (anaplastic astrocytoma) tumors and 18 patients had Grade 4 (glioblastoma multiforme)." | 2.67 | National Cancer Institute (phase II) study of high-grade glioma treated with accelerated hyperfractionated radiation and iododeoxyuridine: results in anaplastic astrocytoma. ( Cook, JA; Epstein, AH; Goffman, TE; Herscher, LL; Kinsella, TJ; Mitchell, JB; Oldfield, EH; Smith, J; Steinberg, SM; Sullivan, FJ, 1994) |
| "Furthermore, in the case of brain tumors, it may circumvent limited drug delivery imposed by the blood-brain barrier." | 1.31 | PET imaging drug distribution after intratumoral injection: the case for (124)I-iododeoxyuridine in malignant gliomas. ( Freitag, P; Gratzl, O; Hausmann, O; Leenders, KL; Maguire, RP; Merlo, A; Missimer, J; Radü, EW; Roelcke, U; Weinreich, R, 2002) |
| "To facilitate cell kinetics studies of brain tumors labeled with thymidine analogs, we developed a new method to identify nuclei labeled sequentially with bromodeoxyuridine (BUdR) and iododeoxyuridine (IUdR) by double staining with immunogold-silver and alkaline phosphatase." | 1.29 | Immunohistochemical double staining with immunogold-silver and alkaline phosphatase to identify nuclear markers of cellular proliferation. ( Davis, RL; Hoshino, T; Ito, S; Shibuya, M, 1993) |
| "Using this method, 100 brain tumors were labeled with bromodeoxyuridine (BUdR) in situ and with iododeoxyuridine in vitro; labeled cells were identified by double staining with immunogold-silver and alkaline phosphatase techniques." | 1.29 | A new method for analyzing the cell kinetics of human brain tumors by double labeling with bromodeoxyuridine in situ and with iododeoxyuridine in vitro. ( Davis, RL; Hoshino, T; Ito, S; Shibuya, M; Wilson, CB, 1993) |
| "Rats with 9L brain tumors received intraperitoneal injections of iododeoxyuridine (IUdR) and bromodeoxyuridine (BUdR) to estimate the duration of the deoxyribonucleic acid (DNA) synthesis phase (Ts) and the potential doubling time (Tp) of individual tumors." | 1.28 | Cell kinetics of rat 9L brain tumors determined by double labeling with iodo- and bromodeoxyuridine. ( Asai, A; Barker, M; Gray, JW; Hoshino, T; Shibui, S; Vanderlaan, M, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (18.37) | 18.7374 |
| 1990's | 27 (55.10) | 18.2507 |
| 2000's | 10 (20.41) | 29.6817 |
| 2010's | 2 (4.08) | 24.3611 |
| 2020's | 1 (2.04) | 2.80 |
| Authors | Studies |
|---|---|
| Shirvalilou, S | 1 |
| Khoei, S | 1 |
| Khoee, S | 1 |
| Mahdavi, SR | 1 |
| Raoufi, NJ | 1 |
| Motevalian, M | 1 |
| Karimi, MY | 1 |
| Rösler, TW | 1 |
| Matusch, A | 1 |
| Librizzi, D | 1 |
| Arias-Carrión, O | 1 |
| Freundlieb, N | 1 |
| Hoeffken, H | 1 |
| Oertel, WH | 1 |
| Depboylu, C | 1 |
| Höglinger, GU | 1 |
| Rebischung, C | 1 |
| Hoffmann, D | 1 |
| Stefani, L | 1 |
| Desruet, MD | 1 |
| Wang, K | 1 |
| Adelstein, SJ | 6 |
| Artignan, X | 1 |
| Vincent, F | 1 |
| Gauchez, AS | 1 |
| Zhang, H | 1 |
| Fagret, D | 1 |
| Vuillez, J | 1 |
| Kassis, AI | 6 |
| Balosso, J | 2 |
| Rousseau, J | 2 |
| Adam, JF | 2 |
| Deman, P | 1 |
| Wu, TD | 1 |
| Guerquin-Kern, JL | 1 |
| Gouget, B | 1 |
| Barth, RF | 1 |
| Estève, F | 2 |
| Elleaume, H | 2 |
| Jang, SJ | 1 |
| Kang, JH | 1 |
| Kim, KI | 1 |
| Lee, TS | 1 |
| Lee, YJ | 1 |
| Lee, KC | 1 |
| Woo, KS | 1 |
| Chung, WS | 1 |
| Kwon, HC | 1 |
| Ryu, CJ | 1 |
| Choi, TH | 1 |
| Choi, CW | 1 |
| Lim, SM | 1 |
| Cheon, GJ | 1 |
| Roelcke, U | 2 |
| Hausmann, O | 1 |
| Merlo, A | 1 |
| Missimer, J | 2 |
| Maguire, RP | 2 |
| Freitag, P | 1 |
| Radü, EW | 1 |
| Weinreich, R | 2 |
| Gratzl, O | 1 |
| Leenders, KL | 2 |
| Buchegger, F | 2 |
| Adamer, F | 1 |
| Schaffland, AO | 1 |
| Kosinski, M | 1 |
| Grannavel, C | 1 |
| Dupertuis, YM | 2 |
| de Tribolet, N | 2 |
| Mach, JP | 2 |
| Delaloye, AB | 1 |
| Schulz, CA | 1 |
| Mehta, MP | 1 |
| Badie, B | 1 |
| McGinn, CJ | 1 |
| Robins, HI | 1 |
| Hayes, L | 1 |
| Chappell, R | 1 |
| Volkman, J | 1 |
| Binger, K | 1 |
| Arzoomanian, R | 1 |
| Simon, K | 1 |
| Alberti, D | 1 |
| Feierabend, C | 1 |
| Tutsch, KD | 1 |
| Kunugi, KA | 1 |
| Wilding, G | 1 |
| Kinsella, TJ | 4 |
| Wu, B | 1 |
| You, C | 1 |
| Liu, XD | 1 |
| Cai, BW | 1 |
| Biston, MC | 1 |
| Boudou, C | 1 |
| Charvet, AM | 1 |
| Cronkite, EP | 1 |
| Fairchild, RG | 2 |
| Miller, ME | 1 |
| Mitchell, JB | 3 |
| Russo, A | 1 |
| Morstyn, G | 1 |
| Glatstein, E | 4 |
| Sullivan, FJ | 1 |
| Herscher, LL | 1 |
| Cook, JA | 2 |
| Smith, J | 1 |
| Steinberg, SM | 2 |
| Epstein, AH | 2 |
| Oldfield, EH | 2 |
| Goffman, TE | 2 |
| Kaplitt, MG | 1 |
| Tjuvajev, JG | 2 |
| Leib, DA | 1 |
| Berk, J | 2 |
| Pettigrew, KD | 1 |
| Posner, JB | 1 |
| Pfaff, DW | 1 |
| Rabkin, SD | 1 |
| Blasberg, RG | 2 |
| Macapinlac, HA | 1 |
| Daghighian, F | 1 |
| Scott, AM | 1 |
| Ginos, JZ | 1 |
| Finn, RD | 2 |
| Kothari, P | 1 |
| Desai, R | 1 |
| Zhang, J | 1 |
| Beattie, B | 3 |
| Tjuvajev, J | 1 |
| Muraki, A | 1 |
| Ginos, J | 1 |
| Koutcher, J | 1 |
| Ballon, D | 1 |
| Finn, R | 1 |
| Dahighian, F | 1 |
| Blasberg, R | 1 |
| Shibuya, M | 3 |
| Ito, S | 3 |
| Davis, RL | 3 |
| Hoshino, T | 5 |
| Urtasun, RC | 1 |
| Cosmatos, D | 1 |
| DelRowe, J | 1 |
| Lester, S | 1 |
| Wasserman, T | 1 |
| Fulton, DS | 1 |
| Wilson, CB | 2 |
| Vaidyanathan, G | 1 |
| Larsen, RH | 1 |
| Zalutsky, MR | 1 |
| Tumeh, SS | 1 |
| Wen, PY | 3 |
| Baranowska-Kortylewicz, J | 3 |
| Van den Abbeele, AD | 3 |
| Zimmerman, RE | 1 |
| Carvalho, PA | 1 |
| Garada, BM | 1 |
| DeSisto, WC | 2 |
| Bailey, NO | 1 |
| Castronovo, FP | 1 |
| Mariani, G | 1 |
| Black, PM | 3 |
| Williams, JA | 3 |
| Dillehay, LE | 3 |
| Tabassi, K | 1 |
| Sipos, E | 1 |
| Fahlman, C | 1 |
| Brem, H | 2 |
| Neshasteh-Riz, A | 2 |
| Angerson, WJ | 2 |
| Reeves, JR | 2 |
| Smith, G | 1 |
| Rampling, R | 2 |
| Mairs, RJ | 2 |
| Makrigiorgos, GM | 1 |
| Metz, KR | 1 |
| Matalka, KZ | 1 |
| Cook, CU | 1 |
| Sahu, SK | 1 |
| Yuan, X | 2 |
| Shastri, VR | 1 |
| Williams, JR | 2 |
| Wideman, CL | 1 |
| Whateley, TL | 1 |
| Reza, MS | 1 |
| Robertson, LM | 1 |
| Owens, J | 1 |
| Allan, D | 1 |
| Graham, DI | 1 |
| von Ammon, K | 1 |
| Yonekawa, Y | 1 |
| Landolt, H | 1 |
| Guenther, I | 1 |
| Crompton, NE | 1 |
| Vontobel, P | 1 |
| Koziorowski, J | 1 |
| Knust, EJ | 1 |
| Vazquez, M | 1 |
| Pichard, C | 1 |
| Slosman, DO | 1 |
| Goffman, T | 1 |
| Dachowski, LJ | 1 |
| Bobo, H | 1 |
| Cook, J | 1 |
| Katz, D | 2 |
| Smith, R | 1 |
| Maeda, T | 1 |
| Asai, A | 2 |
| Prados, MD | 1 |
| Dodson, BA | 1 |
| Goodman, JH | 1 |
| Gahbauer, RA | 1 |
| Kanellitsas, C | 1 |
| Clendenon, NR | 1 |
| Laster, BH | 1 |
| Miller, MA | 2 |
| Mazewski, CM | 1 |
| Yousuf, N | 1 |
| Sheikh, Y | 2 |
| White, LM | 1 |
| Yanik, GA | 1 |
| Hyams, DM | 1 |
| Lampkin, BC | 1 |
| Raza, A | 2 |
| Mazewski, C | 1 |
| Lampkin, B | 1 |
| Sawaya, R | 1 |
| Crone, K | 1 |
| Berger, T | 1 |
| Reising, J | 1 |
| Gray, J | 1 |
| Duprez, A | 1 |
| Barat, JL | 1 |
| Girard, A | 1 |
| Hoffmann, M | 1 |
| Hepner, H | 1 |
| Shibui, S | 1 |
| Barker, M | 1 |
| Vanderlaan, M | 1 |
| Gray, JW | 1 |
| Aaronson, RA | 1 |
| Lampson, LA | 1 |
| Deutsch, M | 1 |
| Rewers, AB | 1 |
| Redgate, S | 1 |
| Fisher, ER | 1 |
| Boggs, SS | 1 |
| Jackson, D | 1 |
| Kinsella, T | 1 |
| Rowland, J | 1 |
| Wright, D | 1 |
| Main, D | 1 |
| Collins, J | 1 |
| Kornblith, P | 1 |
| Schackert, G | 2 |
| Fidler, IJ | 3 |
| Price, JE | 1 |
| Aukerman, SL | 1 |
| Lokshina, AM | 1 |
| Pelevina, II | 1 |
| Levy, NL | 1 |
| Stratton, K | 1 |
| Anderson, A | 1 |
| Koehler, AM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Early Phase I Study of IPdR Absorption, Metabolism, and Safety in Patients With Advanced Solid Tumors and Lymphomas[NCT01240577] | Phase 1 | 10 participants (Actual) | Interventional | 2010-10-26 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for idoxuridine and Brain Neoplasms
| Article | Year |
|---|---|
Are there unexploited possibilities for the therapeutic use of radioactive and stable isotopically labeled DNA precursors and extracorporeal irradiation of the blood in treatment of leukemia?
Topics: Acute Disease; Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Chemical Fractionation; DN | 1983 |
Preclinical animal studies with radioiododeoxyuridine.
Topics: Animals; Brain Neoplasms; Female; Gliosarcoma; Idoxuridine; Iodine Radioisotopes; Mice; Neoplasms, E | 1996 |
[Cell proliferation in human cerebral tumors. In vivo study of 45 cases by incorporation of 5-iododesoxyuridine].
Topics: Adult; Aged; Biopsy; Brain Neoplasms; Cell Division; Female; Humans; Idoxuridine; Male; Middle Aged; | 1990 |
[Radiation sensitization of brain neoplasms by haloid analogs of pyrimidine bases].
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Carcinoma, Ehrlich Tumor; Cricetinae; DNA, Neoplasm; Fe | 1973 |
7 trials available for idoxuridine and Brain Neoplasms
| Article | Year |
|---|---|
Continuous 28-day iododeoxyuridine infusion and hyperfractionated accelerated radiotherapy for malignant glioma: a phase I clinical study.
Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Dose Fractionation, Radiation; Female; Humans; Idoxuridin | 2004 |
The use of halogenated thymidine analogs as clinical radiosensitizers: rationale, current status, and future prospects: non-hypoxic cell sensitizers.
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Cell Survival; Clinical Trials as Topic; Combined Modal | 1984 |
National Cancer Institute (phase II) study of high-grade glioma treated with accelerated hyperfractionated radiation and iododeoxyuridine: results in anaplastic astrocytoma.
Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Female; Glioblastoma; Humans; | 1994 |
Iododeoxyuridine (IUdR) combined with radiation in the treatment of malignant glioma: a comparison of short versus long intravenous dose schedules (RTOG 86-12).
Topics: Adolescent; Adult; Aged; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Drug Administratio | 1993 |
Tumour radiosensitization with the halogenated pyrimidines 5'-bromo- and 5'-iododeoxyuridine.
Topics: Brain Neoplasms; Bromodeoxyuridine; Glioma; Head and Neck Neoplasms; Humans; Idoxuridine; Radiation- | 1992 |
Long-term follow-up on National Cancer Institute Phase I/II study of glioblastoma multiforme treated with iododeoxyuridine and hyperfractionated irradiation.
Topics: Adult; Aged; Brain Neoplasms; Drug Evaluation; Follow-Up Studies; Glioblastoma; Humans; Idoxuridine; | 1992 |
Halogenated pyrimidines as radiosensitizers in the treatment of glioblastoma multiforme.
Topics: Astrocytoma; Brain Neoplasms; Bromodeoxyuridine; Drug Evaluation; Female; Glioblastoma; Humans; Idox | 1987 |
38 other studies available for idoxuridine and Brain Neoplasms
| Article | Year |
|---|---|
Enhancement radiation-induced apoptosis in C6 glioma tumor-bearing rats via pH-responsive magnetic graphene oxide nanocarrier.
Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Liberation; Glioma; Graphite; Hydrogen-Ion C | 2020 |
Diesterified derivatives of 5-iodo-2'-deoxyuridine as cerebral tumor tracers.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Chromatography, High Pressure Liquid; Esterification; Hu | 2014 |
First human treatment of resistant neoplastic meningitis by intrathecal administration of MTX plus (125)IUdR.
Topics: Adult; Antibiotics, Antineoplastic; Antigens, Tumor-Associated, Carbohydrate; Brain Neoplasms; Combi | 2008 |
Intracerebral delivery of 5-iodo-2'-deoxyuridine in combination with synchrotron stereotactic radiation for the therapy of the F98 glioma.
Topics: Animals; Brain Neoplasms; Combined Modality Therapy; Glioma; Idoxuridine; Male; Radiation-Sensitizin | 2009 |
Application of bioluminescence imaging to therapeutic intervention of herpes simplex virus type I - Thymidine kinase/ganciclovir in glioma.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Rela | 2010 |
PET imaging drug distribution after intratumoral injection: the case for (124)I-iododeoxyuridine in malignant gliomas.
Topics: Adult; Aged; Brain; Brain Neoplasms; Female; Humans; Idoxuridine; Injections, Intralesional; Injecti | 2002 |
Highly efficient DNA incorporation of intratumourally injected [125I]iododeoxyuridine under thymidine synthesis blocking in human glioblastoma xenografts.
Topics: Animals; Brain Neoplasms; DNA; Floxuridine; Glioblastoma; Humans; Idoxuridine; Iodine Radioisotopes; | 2004 |
[Therapeutic effect of 125IUdR on the glioma cell line C6 in vitro and in vivo].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Line, Tumor; Glioma; Idoxuridin | 2004 |
Heavy element enhanced synchrotron stereotactic radiotherapy as a promising brain tumour treatment.
Topics: Animals; Biophysical Phenomena; Biophysics; Brain Neoplasms; Contrast Media; Glioma; Humans; Idoxuri | 2008 |
Mutant herpes simplex virus induced regression of tumors growing in immunocompetent rats.
Topics: Animals; Brain; Brain Neoplasms; Humans; Idoxuridine; Immunocompetence; Male; Mutation; Rats; Rats, | 1994 |
Imaging of brain tumor proliferative activity with iodine-131-iododeoxyuridine.
Topics: Adult; Brain Neoplasms; Female; Humans; Idoxuridine; Iodine Radioisotopes; Magnetic Resonance Imagin | 1994 |
Iododeoxyuridine uptake and retention as a measure of tumor growth.
Topics: Animals; Brain Neoplasms; Glioma; Idoxuridine; Iodine Radioisotopes; Male; Rats; Rats, Inbred WF; Ra | 1993 |
Immunohistochemical double staining with immunogold-silver and alkaline phosphatase to identify nuclear markers of cellular proliferation.
Topics: Alkaline Phosphatase; Biomarkers; Brain Neoplasms; Bromodeoxyuridine; Cell Cycle; Cell Division; Cel | 1993 |
A new method for analyzing the cell kinetics of human brain tumors by double labeling with bromodeoxyuridine in situ and with iododeoxyuridine in vitro.
Topics: Biopsy; Brain Neoplasms; Bromodeoxyuridine; Cell Division; Humans; Idoxuridine; Immunohistochemistry | 1993 |
5-[211 At]astato-2'-deoxyuridine, an alpha particle-emitting endoradiotherapeutic agent undergoing DNA incorporation.
Topics: Brain Neoplasms; DNA, Neoplasm; Glioma; Half-Life; Humans; Idoxuridine; Linear Energy Transfer; Tumo | 1996 |
Intratumoral administration of 5-[123I]iodo-2'-deoxyuridine in a patient with a brain tumor.
Topics: Adult; Astrocytoma; Brain Neoplasms; Female; Humans; Idoxuridine; Injections, Intralesional; Iodine | 1996 |
5-[125]iodo-2'-deoxyuridine in the radiotherapy of solid CNS tumors in rats.
Topics: Animals; Brain Neoplasms; Gliosarcoma; Idoxuridine; Iodine Radioisotopes; Male; Neoplasm Transplanta | 1996 |
Implantable biodegradable polymers for IUdR radiosensitization of experimental human malignant glioma.
Topics: Animals; Biodegradation, Environmental; Brain Neoplasms; Decanoic Acids; Drug Implants; Glioma; Huma | 1997 |
Incorporation of iododeoxyuridine in multicellular glioma spheroids: implications for DNA-targeted radiotherapy using Auger electron emitters.
Topics: Antigens, Neoplasm; Antimetabolites; Brain Neoplasms; Glioblastoma; Humans; Idoxuridine; Ki-67 Antig | 1997 |
5-[125I]iodo-2'-deoxyuridine in the radiotherapy of brain tumors in rats.
Topics: Animals; Antineoplastic Agents; Brain; Brain Neoplasms; DNA; Gliosarcoma; Idoxuridine; Injections, I | 1998 |
Synthetic, implantable polymers for local delivery of IUdR to experimental human malignant glioma.
Topics: Animals; Antimetabolites; Brain Neoplasms; Cell Division; Delayed-Action Preparations; Drug Carriers | 1998 |
Comparison of different methods of intracerebral administration of radioiododeoxyuridine for glioma therapy using a rat model.
Topics: Animals; Brain Neoplasms; Coated Materials, Biocompatible; Drug Delivery Systems; Female; Glioma; Id | 2000 |
Imaging brain tumor proliferative activity with [124I]iododeoxyuridine.
Topics: Adult; Aged; Brain; Brain Neoplasms; Cell Division; Female; Fluorodeoxyglucose F18; Humans; Idoxurid | 2000 |
Synthetic, implantable polymers for IUdR radiosensitization of experimental human malignant glioma.
Topics: Animals; Bone Marrow; Brain Neoplasms; Cell Division; Decanoic Acids; Delayed-Action Preparations; D | 1999 |
Fluorodeoxyuridine improves imaging of human glioblastoma xenografts with radiolabeled iododeoxyuridine.
Topics: Animals; Brain Neoplasms; Cell Cycle; DNA, Neoplasm; Drug Synergism; Floxuridine; Glioblastoma; Huma | 2001 |
[Proliferation kinetics of human brain tumors by in situ double labeling with bromodeoxyuridine and iododeoxyuridine].
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Bromodeoxyuridine; Cell Cycle; Cell Division; Child; Child | 1992 |
Cell kinetic analysis of human brain tumors by in situ double labelling with bromodeoxyuridine and iododeoxyuridine.
Topics: Brain Neoplasms; Bromodeoxyuridine; Cell Cycle; Glioma; Humans; Idoxuridine; Meningioma | 1992 |
Theoretical basis and clinical methodology for stereotactic interstitial brain tumor irradiation using iododeoxyuridine as a radiation sensitizer and 145Sm as a brachytherapy source.
Topics: Brachytherapy; Brain Neoplasms; Glioblastoma; Humans; Idoxuridine; Radiation-Sensitizing Agents; Rad | 1990 |
Simultaneous immunohistochemical detection of IUdR and BrdU infused intravenously to cancer patients.
Topics: Antibodies, Monoclonal; Brain Neoplasms; Bromodeoxyuridine; Cell Cycle; Colonic Neoplasms; Humans; I | 1991 |
Observations regarding DNA replication sites in human cells in vivo following infusions of iododeoxyuridine and bromodeoxyuridine.
Topics: Antibodies, Monoclonal; Brain Neoplasms; Bromodeoxyuridine; Cell Nucleus; DNA Replication; Gastroint | 1991 |
Cell kinetics of rat 9L brain tumors determined by double labeling with iodo- and bromodeoxyuridine.
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Cell Cycle; DNA, Neoplasm; Glioma; Idoxuridine; Rats; T | 1990 |
Specific uptake of the auger electron-emitting thymidine analogue 5-[123I/125I]iodo-2'-deoxyuridine in rat brain tumors: diagnostic and therapeutic implications in humans.
Topics: Animals; Autoradiography; Brain Neoplasms; Cell Line; Glioma; Humans; Idoxuridine; Iodine Radioisoto | 1990 |
Intra-cerebral ventricular infusion of 5-iodo-2-deoxyuridine (IUDR) as a radiosensitizer in the treatment of a rat glioma.
Topics: Animals; Brain Neoplasms; Death; Glioma; Idoxuridine; Injections, Intraventricular; Male; Neoplasm T | 1990 |
Development of in vivo models for studies of brain metastasis.
Topics: Animals; Brain; Brain Neoplasms; Carotid Arteries; Disease Models, Animal; Female; Idoxuridine; Iodi | 1988 |
Site-specific metastasis of mouse melanomas and a fibrosarcoma in the brain or meninges of syngeneic animals.
Topics: Animals; Brain Neoplasms; Female; Fibrosarcoma; Idoxuridine; Melanoma, Experimental; Meningeal Neopl | 1988 |
Evidence that the process of murine melanoma metastasis is sequential and selective and contains stochastic elements.
Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; Idoxuridine; Iodine Radioisotopes; Male; Melanom | 1986 |
Use of an in vitro microcytotoxicity test to assess human tumor-specific cell-mediated immunity and its serum-mediated abrogation.
Topics: Antigens, Neoplasm; Brain Neoplasms; Cells, Cultured; Culture Media; Cytotoxicity Tests, Immunologic | 1973 |
Effects of radiation mediating agents on the response of a murine ependymoma to proton irradiation.
Topics: Animals; beta-Aminoethyl Isothiourea; Brain Neoplasms; Ependymoma; Idoxuridine; Mice; Neoplasm Trans | 1966 |