Page last updated: 2024-11-07

idoxuridine and Ataxia Telangiectasia

idoxuridine has been researched along with Ataxia Telangiectasia in 1 studies

Ataxia Telangiectasia: An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of CONJUNCTIVA and SKIN; DYSARTHRIA; B- and T-cell immunodeficiency, and RADIOSENSITIVITY to IONIZING RADIATION. Affected individuals are prone to recurrent sinobronchopulmonary infections, lymphoreticular neoplasms, and other malignancies. Serum ALPHA-FETOPROTEINS are usually elevated. (Menkes, Textbook of Child Neurology, 5th ed, p688) The gene for this disorder (ATM) encodes a cell cycle checkpoint protein kinase and has been mapped to chromosome 11 (11q22-q23).

Research Excerpts

ExcerptRelevanceReference
"Normal and ataxia telangiectasia (AT) human cells were exposed to 10(-5) mole/liter bromodeoxyuridine (BrdUrd) or iododeoxyuridine (IdUrd)."3.67Ataxia telangiectasia cells exhibit the same radiosensitization response by incorporation of BrdUrd or IdUrd as do normal human cells. ( Azzam, EI; Raaphorst, GP; Vadasz, JA, 1985)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Raaphorst, GP1
Azzam, EI1
Vadasz, JA1

Other Studies

1 other study available for idoxuridine and Ataxia Telangiectasia

ArticleYear
Ataxia telangiectasia cells exhibit the same radiosensitization response by incorporation of BrdUrd or IdUrd as do normal human cells.
    Radiation research, 1985, Volume: 103, Issue:3

    Topics: Ataxia Telangiectasia; Bromodeoxyuridine; Cell Survival; Humans; Idoxuridine; Radiation-Sensitizing

1985