idoxuridine has been researched along with Astrocytoma in 6 studies
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-one patients had Grade 3 (anaplastic astrocytoma) tumors and 18 patients had Grade 4 (glioblastoma multiforme)." | 2.67 | National Cancer Institute (phase II) study of high-grade glioma treated with accelerated hyperfractionated radiation and iododeoxyuridine: results in anaplastic astrocytoma. ( Cook, JA; Epstein, AH; Goffman, TE; Herscher, LL; Kinsella, TJ; Mitchell, JB; Oldfield, EH; Smith, J; Steinberg, SM; Sullivan, FJ, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schulz, CA | 1 |
| Mehta, MP | 1 |
| Badie, B | 1 |
| McGinn, CJ | 1 |
| Robins, HI | 1 |
| Hayes, L | 1 |
| Chappell, R | 1 |
| Volkman, J | 1 |
| Binger, K | 1 |
| Arzoomanian, R | 1 |
| Simon, K | 1 |
| Alberti, D | 1 |
| Feierabend, C | 1 |
| Tutsch, KD | 1 |
| Kunugi, KA | 1 |
| Wilding, G | 1 |
| Kinsella, TJ | 3 |
| Sullivan, FJ | 1 |
| Herscher, LL | 1 |
| Cook, JA | 1 |
| Smith, J | 1 |
| Steinberg, SM | 1 |
| Epstein, AH | 1 |
| Oldfield, EH | 1 |
| Goffman, TE | 1 |
| Mitchell, JB | 1 |
| Vokes, EE | 1 |
| Dolan, ME | 1 |
| Krishnasamy, S | 1 |
| Mick, R | 1 |
| Ratain, MJ | 1 |
| Berezin, F | 1 |
| Brachman, D | 1 |
| Whitman, G | 1 |
| Schilsky, RL | 1 |
| Charette, J | 1 |
| Urtasun, RC | 1 |
| Cosmatos, D | 1 |
| DelRowe, J | 1 |
| Lester, S | 1 |
| Wasserman, T | 1 |
| Fulton, DS | 1 |
| Kassis, AI | 1 |
| Tumeh, SS | 1 |
| Wen, PY | 1 |
| Baranowska-Kortylewicz, J | 1 |
| Van den Abbeele, AD | 1 |
| Zimmerman, RE | 1 |
| Carvalho, PA | 1 |
| Garada, BM | 1 |
| DeSisto, WC | 1 |
| Bailey, NO | 1 |
| Castronovo, FP | 1 |
| Mariani, G | 1 |
| Black, PM | 1 |
| Adelstein, SJ | 1 |
| Jackson, D | 1 |
| Kinsella, T | 1 |
| Rowland, J | 1 |
| Wright, D | 1 |
| Katz, D | 1 |
| Main, D | 1 |
| Collins, J | 1 |
| Kornblith, P | 1 |
| Glatstein, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Early Phase I Study of IPdR Absorption, Metabolism, and Safety in Patients With Advanced Solid Tumors and Lymphomas[NCT01240577] | Phase 1 | 10 participants (Actual) | Interventional | 2010-10-26 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for idoxuridine and Astrocytoma
| Article | Year |
|---|---|
Continuous 28-day iododeoxyuridine infusion and hyperfractionated accelerated radiotherapy for malignant glioma: a phase I clinical study.
Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Dose Fractionation, Radiation; Female; Humans; Idoxuridin | 2004 |
National Cancer Institute (phase II) study of high-grade glioma treated with accelerated hyperfractionated radiation and iododeoxyuridine: results in anaplastic astrocytoma.
Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Female; Glioblastoma; Humans; | 1994 |
5-Fluorouracil, hydroxyurea and escalating doses of iododeoxyuridine with concomitant radiotherapy for malignant gliomas: a clinical and pharmacologic analysis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Chemotherapy, Adjuvant; Dr | 1993 |
Iododeoxyuridine (IUdR) combined with radiation in the treatment of malignant glioma: a comparison of short versus long intravenous dose schedules (RTOG 86-12).
Topics: Adolescent; Adult; Aged; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Drug Administratio | 1993 |
Halogenated pyrimidines as radiosensitizers in the treatment of glioblastoma multiforme.
Topics: Astrocytoma; Brain Neoplasms; Bromodeoxyuridine; Drug Evaluation; Female; Glioblastoma; Humans; Idox | 1987 |
1 other study available for idoxuridine and Astrocytoma
| Article | Year |
|---|---|
Intratumoral administration of 5-[123I]iodo-2'-deoxyuridine in a patient with a brain tumor.
Topics: Adult; Astrocytoma; Brain Neoplasms; Female; Humans; Idoxuridine; Injections, Intralesional; Iodine | 1996 |