Page last updated: 2024-11-07

idoxuridine and Adenocarcinoma

idoxuridine has been researched along with Adenocarcinoma in 33 studies

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"To detect and quantify hypoxia in colorectal adenocarcinomas by use of pimonidazole and iododeoxyuridine (IdUrd) as extrinsic markers and carbonic anhydrase IX (CA IX), microvessel density (MVD), epidermal growth-factor receptor (EGFR), and vascular endothelial growth factor (VEGF) as intrinsic markers of hypoxia."3.73Hypoxia in human colorectal adenocarcinoma: comparison between extrinsic and potential intrinsic hypoxia markers. ( Begg, AC; De Schutter, H; Debucquoy, A; Ectors, N; Geboes, K; Goethals, L; Haustermans, KM; McBride, WH; Penninckx, F; Perneel, C, 2006)
" The extent of control of the EMT-6 mammary adenocarcinoma was determined using fractionated radiation (12 irradiations) over a 3-week period using the radiosensitizer 5-chloro-2'-deoxycytidine (CldC) and biomodulators of its metabolism: N-(Phosphonacetyl)-L-aspartate (PALA), tetrahydrouridine and 5-fluoro-2'-deoxycytidine (FdC)."3.69Five-chlorodeoxycytidine and biomodulators of its metabolism result in fifty to eighty percent cures of advanced EMT-6 tumors when used with fractionated radiation. ( Greer, S; Marion, HS; Schwade, J, 1995)
"Seven patients with colorectal adenocarcinoma and one with squamous cell carcinoma of anorectal region were infused preoperatively with iododeoxyuridine (IUdR) and bromodeoxyuridine (BrdU) in sequence (100 mg/m2 x 1 hr each with 1-hr interval in between) to label S-phase cells."3.68Cell cycle parameters and DNA ploidy in colorectal carcinomas. ( Bokhari, J; Hyams, D; Khan, S; Raza, A; Sheikh, Y; Yousuf, N, 1991)
"Reutilization of thymidine (TdR) and 5-iodo-2'-deoxyuridine (I-UdR) released by dying tumour cells was assayed in the syngeneic adenocarcinoma EO 771 by injecting heat killed, labelled tumour cells into tumours."3.67Reutilization of 125I-UdR during growth of a solid mammary carcinoma: implications for the 125I-UdR loss technique. ( Feinendegen, LE; Mühlensiepen, H; Porschen, R; Porschen, W, 1987)
"Ten patients with colorectal cancer were injected intratumorally with [125I]UdR) (0."1.29Tumor targeting in vivo and metabolic fate of 5-[iodine-125]iodo-2'-deoxyuridine following intratumoral injection in patients with colorectal cancer. ( Baranowska-Kortylewicz, J; Cei, A; Collecchi, P; Di Luca, L; Di Sacco, S; Di Stefano, R; Ferdeghini, EM; Mariani, G; Van den Abbeele, AD; Viacava, P, 1993)
"Warfarin inhibits metastasis in the animal model and injection of the Warfarin-dependent coagulation factor complex II, IX, X enhances pulmonary metastasis in the same model."1.28Enhancement of pulmonary tumour seeding by human coagulation factors II, IX, X--an investigation into the possible mechanisms involved. ( George, WD; McCulloch, P; Purushotham, AD, 1991)
" It is concluded that in situ evaluation of tumour activity loss rates in carcinoma EO 771 is not disturbed by toxic effects of I-UdR or 125I-UdR within the dose limits mentioned."1.27Evaluation of radio- and chemotoxic effects of 125I-UdR on tumour growth and host survival. ( Feinendegen, LE; Mühlensiepen, H; Porschen, R; Porschen, W, 1985)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199014 (42.42)18.7374
1990's12 (36.36)18.2507
2000's6 (18.18)29.6817
2010's1 (3.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pan, Q1
Nicholson, AM1
Barr, H1
Harrison, LA1
Wilson, GD3
Burkert, J1
Jeffery, R1
Alison, MR1
Looijenga, L1
Lin, WR1
McDonald, SA1
Wright, NA1
Harrison, R1
Peppelenbosch, MP1
Jankowski, JA1
CALABRESI, P1
CREASEY, WA1
PRUSOFF, H1
WELCH, AD1
CLIFTON, KH3
SZYBALSKI, W1
HEIDELBERGER, C1
GOLLIN, FF1
ANSFIELD, FJ1
VERMUND, H1
Chi, KH1
Wang, HE1
Wang, YS1
Chou, SL1
Yu, HM1
Tseng, YH1
Hwang, IM1
Lui, WY1
Baranowska-Kortylewicz, J2
Nearman, J1
Goethals, L1
Debucquoy, A1
Perneel, C1
Geboes, K1
Ectors, N1
De Schutter, H1
Penninckx, F1
McBride, WH1
Begg, AC1
Haustermans, KM1
Porschen, R4
Porschen, W4
Mühlensiepen, H4
Feinendegen, LE4
Hamilton, E1
Dobbin, J1
Greer, S1
Schwade, J1
Marion, HS1
Wilson, MS3
Anderson, E1
Bell, JC1
Pearson, JM1
Haboubi, NY1
James, RD3
Schofield, PF3
Yoshida, K1
Fujikawa, T1
Tanabe, A1
Sakurai, K1
Mariani, G1
Cei, A1
Collecchi, P1
Van den Abbeele, AD1
Di Luca, L1
Di Stefano, R1
Viacava, P1
Ferdeghini, EM1
Di Sacco, S1
West, CM2
Roberts, SA2
Philip, PA1
Kaklamanis, L1
Carmichael, J1
Tonkin, K1
Morrison, H1
Gatter, K1
Harris, AL1
Page, GG1
Blakely, WP1
Ben-Eliyahu, S1
Yasui, L1
Hughes, A1
DeSombre, E1
Mach, RH1
Huang, Y1
Buchheimer, N1
Kuhner, R1
Wu, L1
Morton, TE1
Wang, L1
Ehrenkaufer, RL1
Wallen, CA1
Wheeler, KT1
Riches, AC1
Gore, D1
Docherty, J1
Littlewood, V1
Fritze, D1
Kern, DH2
Drogemuller, CR1
Pilch, YH2
Hughes, AM1
Calvin, M1
Kelly, SA1
Gschmeissner, S1
East, N1
Balkwill, FR1
Purushotham, AD1
McCulloch, P1
George, WD1
Yousuf, N1
Khan, S1
Sheikh, Y1
Hyams, D1
Bokhari, J1
Raza, A1
Bagshawe, KD2
Sharma, K1
Southall, PJ1
Boden, JA1
Boxer, GM1
Patridge, TA1
Antoniw, P1
Pedley, RB1
Humm, JL1
Sharma, SK1
Boxer, G1
Bornschein, R1
Kucera, LS1
Simonson, J1
Veltman, LL1
Yatvin, MB2
Crouse, DT1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Epidural Anesthesia-analgesia on Long-term Survival in Patients After Lung Cancer Surgery: A Randomized Controlled Trial[NCT02801409]400 participants (Actual)Interventional2015-05-25Completed
Impact of Perioperative Dexmedetomidine on Long-term Survival in Older Patients After Cancer Surgery: a Multicenter Randomized Trial[NCT06030804]4,532 participants (Anticipated)Interventional2023-09-12Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

33 other studies available for idoxuridine and Adenocarcinoma

ArticleYear
Identification of lineage-uncommitted, long-lived, label-retaining cells in healthy human esophagus and stomach, and in metaplastic esophagus.
    Gastroenterology, 2013, Volume: 144, Issue:4

    Topics: Adenocarcinoma; Adult; Barrett Esophagus; Biopsy, Needle; Case-Control Studies; Cell Cycle; Cell Tra

2013
Clinical and pharmacological studies with 5-iodo-2'-deoxycytidine.
    Cancer research, 1963, Volume: 23

    Topics: Adenocarcinoma; Bromodeoxycytidine; Carcinoma; Carcinoma, Squamous Cell; Deoxycytidine; Hodgkin Dise

1963
INCORPORATION OF I-125-LABELED IODODEOXYURIDINE INTO THE DEOXYRIBONUCLEIC ACID OF MURINE AND HUMAN TISSUES FOLLOWING THERAPEUTIC DOSES.
    Cancer research, 1963, Volume: 23

    Topics: Adenocarcinoma; Animals; DNA; DNA, Neoplasm; Floxuridine; Geriatrics; Idoxuridine; Intestine, Small;

1963
Antisense thymidylate synthase electrogene transfer to increase uptake of radiolabeled iododeoxyuridine in a murine model.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2004, Volume: 45, Issue:3

    Topics: Adenocarcinoma; Animals; BALB 3T3 Cells; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; DNA, Antis

2004
DNA uptake of 131I-iododeoxyuridine.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46, Issue:5

    Topics: Adenocarcinoma; Animals; BALB 3T3 Cells; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; DNA, Antis

2005
Hypoxia in human colorectal adenocarcinoma: comparison between extrinsic and potential intrinsic hypoxia markers.
    International journal of radiation oncology, biology, physics, 2006, May-01, Volume: 65, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Analysis of Variance; Biomarkers; Carbonic Anhydrase

2006
Cell loss from viable and necrotic tumour regions measured by 125I-UdR.
    Cell and tissue kinetics, 1983, Volume: 16, Issue:6

    Topics: Adenocarcinoma; Animals; Cell Division; Cell Survival; Idoxuridine; Male; Mice; Mice, Inbred C57BL;

1983
[3H]thymidine labels less than half of the DNA-synthesizing cells in the mouse tumour, carcinoma NT.
    Cell and tissue kinetics, 1982, Volume: 15, Issue:4

    Topics: Adenocarcinoma; Animals; Cell Division; Deoxyuridine; DNA, Neoplasm; Female; Idoxuridine; Male; Mice

1982
Five-chlorodeoxycytidine and biomodulators of its metabolism result in fifty to eighty percent cures of advanced EMT-6 tumors when used with fractionated radiation.
    International journal of radiation oncology, biology, physics, 1995, Jul-15, Volume: 32, Issue:4

    Topics: Adenocarcinoma; Animals; Aspartic Acid; Body Weight; Deoxycytidine; Idoxuridine; Mammary Neoplasms,

1995
An evaluation of five different methods for estimating proliferation in human colorectal adenocarcinomas.
    Surgical oncology, 1994, Volume: 3, Issue:5

    Topics: Adenocarcinoma; Antibodies, Monoclonal; Cell Division; Colorectal Neoplasms; Flow Cytometry; Humans;

1994
Quantitative analysis of distribution and fate of human lung cancer emboli labeled with 125I-5-iodo-2'-deoxyuridine in nude mice.
    Surgery today, 1993, Volume: 23, Issue:11

    Topics: Adenocarcinoma; Animals; Female; Humans; Idoxuridine; In Vitro Techniques; Iodine Radioisotopes; Iso

1993
Tumor targeting in vivo and metabolic fate of 5-[iodine-125]iodo-2'-deoxyuridine following intratumoral injection in patients with colorectal cancer.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1993, Volume: 34, Issue:7

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Autoradiography; Colorectal Neoplasms; Female; Humans; Idox

1993
Intra-tumoral heterogeneity of tumour potential doubling times (Tpot) in colorectal cancer.
    British journal of cancer, 1993, Volume: 68, Issue:3

    Topics: Adenocarcinoma; Biopsy; Cell Division; Colorectal Neoplasms; DNA, Neoplasm; Flow Cytometry; Humans;

1993
The influence of high dose hydroxyurea on the incorporation of 5-iodo-2-deoxyuridine (IUdR) by human bone marrow and tumour cells in vivo.
    British journal of cancer, 1993, Volume: 67, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Biopsy,

1993
An assessment of the reliability and reproducibility of measurement of potential doubling times (Tpot) in human colorectal cancers.
    British journal of cancer, 1993, Volume: 67, Issue:4

    Topics: Adenocarcinoma; Cell Cycle; Cell Division; Colorectal Neoplasms; DNA, Neoplasm; Flow Cytometry; Huma

1993
Evidence that postoperative pain is a mediator of the tumor-promoting effects of surgery in rats.
    Pain, 2001, Feb-01, Volume: 90, Issue:1-2

    Topics: Adenocarcinoma; Analgesics, Opioid; Anesthetics, Local; Animals; Antiviral Agents; Bupivacaine; Expl

2001
Evidence that postoperative pain is a mediator of the tumor-promoting effects of surgery in rats.
    Pain, 2001, Feb-01, Volume: 90, Issue:1-2

    Topics: Adenocarcinoma; Analgesics, Opioid; Anesthetics, Local; Animals; Antiviral Agents; Bupivacaine; Expl

2001
Evidence that postoperative pain is a mediator of the tumor-promoting effects of surgery in rats.
    Pain, 2001, Feb-01, Volume: 90, Issue:1-2

    Topics: Adenocarcinoma; Analgesics, Opioid; Anesthetics, Local; Animals; Antiviral Agents; Bupivacaine; Expl

2001
Evidence that postoperative pain is a mediator of the tumor-promoting effects of surgery in rats.
    Pain, 2001, Feb-01, Volume: 90, Issue:1-2

    Topics: Adenocarcinoma; Analgesics, Opioid; Anesthetics, Local; Animals; Antiviral Agents; Bupivacaine; Expl

2001
Relative biological effectiveness of accumulated 125IdU and 125I-estrogen decays in estrogen receptor-expressing MCF-7 human breast cancer cells.
    Radiation research, 2001, Volume: 155, Issue:2

    Topics: Adenocarcinoma; Breast Neoplasms; Cell Nucleus; Cell Survival; DNA Damage; DNA, Neoplasm; Dose-Respo

2001
[[(18)F]N-(4'-fluorobenzyl)-4-(3-bromophenyl) acetamide for imaging the sigma receptor status of tumors: comparison with [(18)F]FDG, and [(125)I]IUDR.
    Nuclear medicine and biology, 2001, Volume: 28, Issue:4

    Topics: Acetamides; Adenocarcinoma; Animals; Female; Fluorodeoxyglucose F18; Idoxuridine; Mammary Neoplasms,

2001
The use of 5-(125I)iodo-2'-deoxyuridine for monitoring DNA synthesis in organ culture.
    Journal of anatomy, 1976, Volume: 121, Issue:Pt 2

    Topics: Adenocarcinoma; Animals; DNA; DNA, Neoplasm; Humans; Hydroxyurea; Idoxuridine; Iodine Radioisotopes;

1976
A new micromethod for the detection of HL-A antigens on cultured human tumor cells.
    Transplantation, 1975, Volume: 20, Issue:3

    Topics: Adenocarcinoma; Antibody Specificity; Colonic Neoplasms; Culture Techniques; Cytotoxicity Tests, Imm

1975
Cytocidal effect of rifamycin derivatives on ascites tumor cells: studies with [125I]iododeoxyuridine.
    Cancer letters, 1979, Volume: 6, Issue:1

    Topics: Adenocarcinoma; Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cell Survival; Female; Idoxuridine; Io

1979
Enhancement of metastatic potential by gamma-interferon.
    Cancer research, 1991, Aug-01, Volume: 51, Issue:15

    Topics: Adenocarcinoma; Animals; Antibodies; Cell Adhesion; Cell Division; Colonic Neoplasms; Extracellular

1991
Enhancement of pulmonary tumour seeding by human coagulation factors II, IX, X--an investigation into the possible mechanisms involved.
    British journal of cancer, 1991, Volume: 64, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cell Division; Factor IX; Factor X; Femal

1991
Cell cycle parameters and DNA ploidy in colorectal carcinomas.
    The Journal of surgical research, 1991, Volume: 51, Issue:6

    Topics: Adenocarcinoma; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Cycle; Colorectal Neoplasms; DNA;

1991
Selective uptake of toxic nucleoside (125IUdR) by resistant cancer.
    The British journal of radiology, 1991, Volume: 64, Issue:757

    Topics: Adenocarcinoma; Animals; Cell Line; Choriocarcinoma; Colon; Colonic Neoplasms; Cytarabine; Drug Resi

1991
Tissue dose estimates following the selective uptake of 125IUdR and other radiolabelled thymidine precursors in resistant tumours.
    The British journal of radiology, 1991, Volume: 64, Issue:757

    Topics: Adenocarcinoma; Animals; Astatine; Bromine Radioisotopes; Cell Nucleus; Cell Survival; Choriocarcino

1991
Cell loss from viable and necrotic tumor regions after local gamma irradiation measured by 125I-UdR.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1987, Volume: 163, Issue:2

    Topics: Adenocarcinoma; Animals; DNA, Neoplasm; Gamma Rays; Idoxuridine; Iodine Radioisotopes; Male; Mammary

1987
Reutilization of 125I-UdR during growth of a solid mammary carcinoma: implications for the 125I-UdR loss technique.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1987, Volume: 163, Issue:11

    Topics: Adenocarcinoma; Animals; Cell Survival; Idoxuridine; Iodine Radioisotopes; Male; Mammary Neoplasms,

1987
Evaluation of radio- and chemotoxic effects of 125I-UdR on tumour growth and host survival.
    Radiation and environmental biophysics, 1985, Volume: 24, Issue:3

    Topics: Adenocarcinoma; Animals; DNA, Neoplasm; Idoxuridine; Iodine Radioisotopes; Male; Mammary Neoplasms,

1985
Isolation and characterization of a cell line from the cocultivation of Lucké renal tumor cells and nontransformed feeder cells.
    Journal of the National Cancer Institute, 1974, Volume: 53, Issue:2

    Topics: Adenocarcinoma; Animals; Anterior Chamber; Anura; Bromodeoxyuridine; Cell Division; Cell Line; Cytop

1974
Immune cytolysis of human tumor cells mediated by xenogeneic "immune" RNA.
    Cellular immunology, 1974, Volume: 13, Issue:3

    Topics: Adenocarcinoma; Animals; Cytotoxicity Tests, Immunologic; Humans; Idoxuridine; Iodine Radioisotopes;

1974
Cell population growth and cell loss in the MTG-B mouse mammary carcinoma.
    Cancer research, 1970, Volume: 30, Issue:3

    Topics: Adenocarcinoma; Animals; Cell Division; DNA, Neoplasm; Idoxuridine; Iodine Radioisotopes; Mammary Ne

1970
Studies on the mechanism of the stimulatory effect of lethally irradiated cells on tumor inocula.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1970, Volume: 133, Issue:4

    Topics: Adenocarcinoma; Animals; Cell Nucleus; Hindlimb; Idoxuridine; Iodine Isotopes; Male; Mammary Neoplas

1970