Page last updated: 2024-10-28

idebenone and Reperfusion Injury

idebenone has been researched along with Reperfusion Injury in 7 studies

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"Idebenone is a well-appreciated mitochondrial protectant while the mechanisms underlying the neuroprotection in cerebral ischemia and reperfusion (I/R) remain elusive."3.96Idebenone attenuates cerebral inflammatory injury in ischemia and reperfusion via dampening NLRP3 inflammasome activity. ( Gong, Z; He, L; Li, X; Pan, J; Peng, J; Peng, Y; Shen, Q; Wang, H, 2020)
"This study shows that Ca2+ reperfusion injury of astrocytes is accompanied by apoptosis as evidenced by DNA fragmentation and nuclear condensation."2.41[Delayed apoptosis and its regulation in astrocytes]. ( Takuma, K, 2001)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's4 (57.14)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Peng, J1
Wang, H1
Gong, Z1
Li, X1
He, L1
Shen, Q1
Pan, J1
Peng, Y1
Schütz, E1
Wieland, E2
Hensel, A1
Niedmann, PD1
Dreiss, A1
Armstrong, VW1
Schuff-Werner, P1
Oellerich, M2
Matsuda, T2
Takuma, K3
Lee, E2
Baba, A2
Braun, F1
Schtüz, E1
Yoshida, T1
Mori, K1
Kishi, T1
Pluta, R1

Reviews

2 reviews available for idebenone and Reperfusion Injury

ArticleYear
[Cell injury and its protection in astrocytes].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1999, Volume: 114, Issue:5

    Topics: Animals; Apoptosis; Astrocytes; Benzoquinones; Calcium; Calpain; Cell Death; Cells, Cultured; Humans

1999
[Delayed apoptosis and its regulation in astrocytes].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2001, Volume: 121, Issue:9

    Topics: Animals; Apoptosis; Astrocytes; Benzoquinones; Calcium; Cells, Cultured; Diethylamines; Humans; MAP

2001

Other Studies

5 other studies available for idebenone and Reperfusion Injury

ArticleYear
Idebenone attenuates cerebral inflammatory injury in ischemia and reperfusion via dampening NLRP3 inflammasome activity.
    Molecular immunology, 2020, Volume: 123

    Topics: Animals; Animals, Newborn; Brain Ischemia; Cells, Cultured; Encephalitis; Inflammasomes; Male; Mice;

2020
Suppression of leukocyte-enhanced cold ischemia/reperfusion injury of liver endothelium with the benzoquinone antioxidant idebenone.
    Clinical biochemistry, 1997, Volume: 30, Issue:8

    Topics: Animals; Antioxidants; Benzoquinones; Cold Temperature; Depression, Chemical; Endothelium; Leukocyte

1997
c-fos and c-jun mRNA expression in a pig liver model of ischemia/reperfusion: effect of extended cold storage and the antioxidant idebenone.
    Clinical biochemistry, 2000, Volume: 33, Issue:4

    Topics: Animals; Antioxidants; Benzoquinones; Cold Temperature; Disease Models, Animal; Female; Gene Express

2000
CV-2619 protects cultured astrocytes against reperfusion injury via nerve growth factor production.
    European journal of pharmacology, 2000, Oct-20, Volume: 406, Issue:3

    Topics: Animals; Antioxidants; Astrocytes; Benzoquinones; Cells, Cultured; Nerve Growth Factor; Neuroprotect

2000
No effect of anti-oxidative therapy on cerebral amyloidosis following ischemia-reperfusion brain injury.
    Folia neuropathologica, 2000, Volume: 38, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Antioxidants; Benzoquinones

2000