idebenone has been researched along with Orphan Diseases in 2 studies
Orphan Diseases: Rare diseases that have not been well studied.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Low-quality evidence from two small, published, randomised controlled trials neither support nor refute an effect from antioxidants (idebenone, or a combination of coenzyme Q10 and vitamin E) on the neurological status of people with Friedreich ataxia, measured with a validated neurological rating scale." | 4.93 | Pharmacological treatments for Friedreich ataxia. ( Brassington, R; Fahey, M; Kearney, M; Orrell, RW; Pandolfo, M, 2016) |
| "More than 10 studies used idebenone in the treatment of Friedreich ataxia but only one small RCT, with 29 participants, using the synthetic antioxidant idebenone 5 mg/kg, fulfilled the selection criteria for this review." | 4.88 | Antioxidants and other pharmacological treatments for Friedreich ataxia. ( Fahey, M; Kearney, M; Orrell, RW; Pandolfo, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kearney, M | 2 |
| Orrell, RW | 2 |
| Fahey, M | 2 |
| Brassington, R | 1 |
| Pandolfo, M | 2 |
2 reviews available for idebenone and Orphan Diseases
| Article | Year |
|---|---|
Pharmacological treatments for Friedreich ataxia.
Topics: Antioxidants; Friedreich Ataxia; Heart; Humans; Hypertrophy, Left Ventricular; Randomized Controlled | 2016 |
Antioxidants and other pharmacological treatments for Friedreich ataxia.
Topics: Antioxidants; Friedreich Ataxia; Humans; Hypertrophy, Left Ventricular; Randomized Controlled Trials | 2012 |