idebenone has been researched along with Multiple Sclerosis in 3 studies
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Idebenone was well tolerated but did not inhibit disability progression or CNS tissue destruction." | 2.94 | Idebenone does not inhibit disability progression in primary progressive MS. ( Bielekova, B; Komori, M; Kosa, P; Leinonen, M; Masvekar, R; Phillips, J; Sandford, M; Wichman, A; Wu, T, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Kosa, P | 1 |
| Wu, T | 1 |
| Phillips, J | 1 |
| Leinonen, M | 1 |
| Masvekar, R | 1 |
| Komori, M | 1 |
| Wichman, A | 1 |
| Sandford, M | 1 |
| Bielekova, B | 1 |
| Chang, M | 1 |
| Szewka, AJ | 1 |
| Toffoli, D | 1 |
| Newman, NJ | 1 |
| Biousse, V | 1 |
1 trial available for idebenone and Multiple Sclerosis
| Article | Year |
|---|---|
Idebenone does not inhibit disability progression in primary progressive MS.
Topics: Axons; Biomarkers; Disease Progression; Double-Blind Method; Humans; Multiple Sclerosis; Multiple Sc | 2020 |
2 other studies available for idebenone and Multiple Sclerosis
| Article | Year |
|---|---|
Leber's hereditary optic neuropathy misdiagnosed as optic neuritis and Lyme disease in a patient with multiple sclerosis.
Topics: Adult; Antioxidants; Diagnosis, Differential; Diagnostic Errors; Humans; Lyme Disease; Magnetic Reso | 2018 |
Updates in neuro-ophthalmology. Highlights from the 37th annual meeting of the North American Neuro-Ophthalmology Society,February 5-10, 2011, Vancouver, Canada.
Topics: Burkholderia; Canada; Giant Cell Arteritis; Humans; Multiple Sclerosis; Neurology; Ophthalmology; Op | 2011 |