idebenone has been researched along with Choline Deficiency in 1 studies
Choline Deficiency: A condition produced by a deficiency of CHOLINE in animals. Choline is known as a lipotropic agent because it has been shown to promote the transport of excess fat from the liver under certain conditions in laboratory animals. Combined deficiency of choline (included in the B vitamin complex) and all other methyl group donors causes liver cirrhosis in some animals. Unlike compounds normally considered as vitamins, choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Idebenone was recently identified as the first small-molecule Shc inhibitor drug." | 1.62 | Shc inhibitor idebenone ameliorates liver injury and fibrosis in dietary NASH in mice. ( Cortopassi, G; Hui, CK; Jiang, JX; Montgomery, C; Tomilov, A; Török, NJ, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, JX | 1 |
| Tomilov, A | 1 |
| Montgomery, C | 1 |
| Hui, CK | 1 |
| Török, NJ | 1 |
| Cortopassi, G | 1 |
1 other study available for idebenone and Choline Deficiency
| Article | Year |
|---|---|
Shc inhibitor idebenone ameliorates liver injury and fibrosis in dietary NASH in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Choline Deficiency; Diet; Disease Models | 2021 |