idebenone has been researched along with Cerebrovascular Disorders in 16 studies
Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A daily dose of 90 mg of idebenone was given to nine patients with cerebrovascular disorders to investigate its effects on clinical symptoms and electroencephalograms (EEG)." | 7.67 | Effects of idebenone on electroencephalograms of patients with cerebrovascular disorders. ( Kifune, Y; Miyasaka, M; Mori, K; Nakano, T; Ohtaka, T, 1989) |
| "Idebenone treatment (30 mg/kg per day, p." | 5.28 | Effects of idebenone on lipid peroxidation and hemolysis in erythrocytes of stroke-prone spontaneously hypertensive rats. ( Nagaoka, A; Shibota, M; Suno, M, 1989) |
| "The effects of a novel compound, 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone (idebenone, CV-2619), on cerebral and renal vascular changes were examined in stroke-prone spontaneously hypertensive rats (SHRSP) and in rats with experimentally induced hypertension." | 3.67 | Inhibitory effect of idebenone (CV-2619), a novel compound, on vascular lesions in hypertensive rats. ( Iwatsuka, H; Kakihana, M; Nagaoka, A; Shino, A, 1984) |
| "A daily dose of 90 mg of idebenone was given to nine patients with cerebrovascular disorders to investigate its effects on clinical symptoms and electroencephalograms (EEG)." | 3.67 | Effects of idebenone on electroencephalograms of patients with cerebrovascular disorders. ( Kifune, Y; Miyasaka, M; Mori, K; Nakano, T; Ohtaka, T, 1989) |
| "Treatment with oxiracetam (400 mg/kg/d p." | 1.28 | Effect of oxiracetam on cerebrovascular impairment in rats. ( Hasegawa, Y; Inukai, T; Kometani, M; Nakao, N; Okada, M; Takemori, E, 1991) |
| "Transient and global cerebral ischemia in rats, produced by 4-vessel occlusion for 200 s immediately after the acquisition trial of passive avoidance learning, shortened the latencies in the retention test trial performed 24 h later." | 1.28 | Effects of idebenone on memory impairment induced in ischemic and embolization models of cerebrovascular disturbance in rats. ( Kiyota, Y; Miyamoto, M; Nagaoka, A; Nagawa, Y; Take, Y; Yamazaki, N, 1989) |
| "Idebenone treatment (30 mg/kg per day, p." | 1.28 | Effects of idebenone on lipid peroxidation and hemolysis in erythrocytes of stroke-prone spontaneously hypertensive rats. ( Nagaoka, A; Shibota, M; Suno, M, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (68.75) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suno, M | 2 |
| Shibota, M | 2 |
| Nagaoka, A | 9 |
| Shino, A | 1 |
| Kakihana, M | 2 |
| Iwatsuka, H | 1 |
| Otomo, E | 1 |
| Nagisa, Y | 1 |
| Mihara, T | 1 |
| Hamajo, K | 1 |
| Imamoto, T | 1 |
| Kandori, H | 1 |
| Oda, E | 1 |
| Chatani, F | 1 |
| Tagami, M | 1 |
| Yamagata, K | 1 |
| Ikeda, K | 1 |
| Nara, Y | 1 |
| Fujino, H | 1 |
| Kubota, A | 1 |
| Numano, F | 1 |
| Yamori, Y | 1 |
| Kometani, M | 1 |
| Okada, M | 1 |
| Takemori, E | 1 |
| Hasegawa, Y | 1 |
| Nakao, N | 1 |
| Inukai, T | 1 |
| Kawakami, M | 1 |
| Itoh, T | 1 |
| Ihara, Y | 1 |
| Namba, R | 1 |
| Kuroda, S | 1 |
| Sato, T | 1 |
| Shirabe, T | 1 |
| Fujiwara, K | 1 |
| Yamazaki, N | 2 |
| Nomura, M | 1 |
| Nagawa, Y | 2 |
| Kiyota, Y | 1 |
| Take, Y | 1 |
| Miyamoto, M | 1 |
| Nagai, Y | 2 |
| Yoshida, K | 2 |
| Narumi, S | 2 |
| Tanayama, S | 2 |
| Nakano, T | 1 |
| Miyasaka, M | 1 |
| Mori, K | 1 |
| Ohtaka, T | 1 |
| Kifune, Y | 1 |
2 reviews available for idebenone and Cerebrovascular Disorders
| Article | Year |
|---|---|
[Cerebral circulatory improvers and metabolic activators].
Topics: Aged; Antidepressive Agents; Benzoquinones; Brain; Cerebrovascular Circulation; Cerebrovascular Diso | 1994 |
Idebenone - monograph.
Topics: Alzheimer Disease; Animals; Antioxidants; Benzoquinones; Cerebrovascular Disorders; Friedreich Ataxi | 2001 |
14 other studies available for idebenone and Cerebrovascular Disorders
| Article | Year |
|---|---|
[Effect of CV-2619 (idebenone) on the half-life and hemolysis of red blood cells in stroke-prone spontaneously hypertensive rats (SHRSP)].
Topics: Animals; Benzoquinones; Cerebrovascular Disorders; Erythrocyte Aging; Half-Life; Hemolysis; Male; Qu | 1984 |
Inhibitory effect of idebenone (CV-2619), a novel compound, on vascular lesions in hypertensive rats.
Topics: Animals; Benzoquinones; Blood Pressure; Body Weight; Brain; Cerebrovascular Disorders; Hypertension; | 1984 |
[Beneficial effects of the combination of idebenone and manidipine 2HCl on neurological deficits and histological changes following cerebrovascular lesions in stroke-prone spontaneously hypertensive rats].
Topics: Administration, Oral; Animals; Benzoquinones; Brain; Calcium Channel Blockers; Cerebrovascular Disor | 1995 |
Vitamin E prevents apoptosis in cortical neurons during hypoxia and oxygen reperfusion.
Topics: Animals; Antioxidants; Apoptosis; Benzoquinones; Cerebral Cortex; Cerebrovascular Disorders; Free Ra | 1998 |
Effect of oxiracetam on cerebrovascular impairment in rats.
Topics: Animals; Behavior, Animal; Benzoquinones; Blood Pressure; Cerebral Arteries; Cerebral Infarction; Ce | 1991 |
[Effects of idebenone on monoamine metabolites in the cerebrospinal fluid of patients with cerebrovascular dementia].
Topics: Aged; Benzoquinones; Biogenic Amines; Cerebrovascular Disorders; Chromatography, High Pressure Liqui | 1986 |
Mitochondrial encephalomyopathy (MELAS): pathological study and successful therapy with coenzyme Q10 and idebenone.
Topics: Acidosis, Lactic; Adolescent; Benzoquinones; Brain Diseases; Cerebrovascular Disorders; Female; Huma | 1989 |
Effects of idebenone on neurological deficits following cerebrovascular lesions in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Benzoquinones; Body Weight; Brain; Cerebrovascular Disorders; Dose-Response Relationship, D | 1989 |
Idebenone improves learning and memory impairment induced by cholinergic or serotonergic dysfunction in rats.
Topics: Acetylcholine; Animals; Benzoquinones; Cerebral Cortex; Cerebrovascular Disorders; Discrimination Le | 1989 |
Effects of idebenone on memory impairment induced in ischemic and embolization models of cerebrovascular disturbance in rats.
Topics: Administration, Oral; Animals; Avoidance Learning; Benzoquinones; Brain Ischemia; Cerebrovascular Di | 1989 |
Brain distribution of idebenone and its effect on local cerebral glucose utilization in rats.
Topics: Animals; Benzoquinones; Brain; Cerebrovascular Disorders; Glucose; Male; Quinones; Rats; Rats, Inbre | 1989 |
Effects of idebenone on lipid peroxidation and hemolysis in erythrocytes of stroke-prone spontaneously hypertensive rats.
Topics: Animals; Benzoquinones; Cerebrovascular Disorders; Erythrocytes; Hemolysis; Hypertension; Lipid Pero | 1989 |
Effects of idebenone on electroencephalograms of patients with cerebrovascular disorders.
Topics: Adult; Aged; Aged, 80 and over; Benzoquinones; Cerebrovascular Disorders; Electroencephalography; Fe | 1989 |
[Brain distribution of idebenone (CV-2619) and its effect on local cerebral glucose utilization in rats].
Topics: Administration, Oral; Animals; Benzoquinones; Brain; Cerebrovascular Disorders; Glucose; Injections, | 1986 |