Page last updated: 2024-10-28

idebenone and Cardiomyopathies

idebenone has been researched along with Cardiomyopathies in 7 studies

Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).

Research Excerpts

ExcerptRelevanceReference
"Several reports in the literature describe the effects of low-dose (5 mg/kg/day) idebenone in significantly reducing cardiac hypertrophy in patients with Friedreich ataxia."8.85Clinical experience with high-dose idebenone in Friedreich ataxia. ( Di Prospero, NA; Fischbeck, K; Schulz, JB, 2009)
"Several reports in the literature describe the effects of low-dose (5 mg/kg/day) idebenone in significantly reducing cardiac hypertrophy in patients with Friedreich ataxia."4.85Clinical experience with high-dose idebenone in Friedreich ataxia. ( Di Prospero, NA; Fischbeck, K; Schulz, JB, 2009)
"The dystrophinopathies include Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), and X-linked dilated cardiomyopathy (XLDCM)."2.58Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X-linked dilated cardiomyopathy. ( Bourke, JP; Bueser, T; Quinlivan, R, 2018)
"Friedreich's ataxia is caused by a deficiency of frataxin, a protein involved in regulation of mitochondrial iron content."1.30Effect of idebenone on cardiomyopathy in Friedreich's ataxia: a preliminary study. ( Chantrel-Groussard, K; Munnich, A; Rötig, A; Rustin, P; Sidi, D; von Kleist-Retzow, JC, 1999)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bourke, JP1
Bueser, T1
Quinlivan, R1
Schulz, JB1
Di Prospero, NA1
Fischbeck, K1
Anheim, M1
Mariani, LL1
Calvas, P1
Cheuret, E1
Zagnoli, F1
Odent, S1
Seguela, C1
Marelli, C1
Fritsch, M1
Delaunoy, JP1
Brice, A1
Dürr, A1
Koenig, M1
Myers, L1
Farmer, JM1
Wilson, RB1
Friedman, L1
Tsou, A1
Perlman, SL1
Subramony, SH1
Gomez, CM1
Ashizawa, T1
Wilmot, GR1
Mathews, KD1
Balcer, LJ1
Lynch, DR1
Rustin, P2
von Kleist-Retzow, JC1
Chantrel-Groussard, K1
Sidi, D1
Munnich, A2
Rötig, A1
Lerman-Sagie, T1
Lev, D1
Yanoov, M1
Leshinsky-Silver, E1
Sagie, A1
Ben-Gal, T1
Schöls, L1
Vorgerd, M1
Schillings, M1
Skipka, G1
Zange, J1

Reviews

2 reviews available for idebenone and Cardiomyopathies

ArticleYear
Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X-linked dilated cardiomyopathy.
    The Cochrane database of systematic reviews, 2018, Oct-16, Volume: 10

    Topics: Adolescent; Adult; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antih

2018
Clinical experience with high-dose idebenone in Friedreich ataxia.
    Journal of neurology, 2009, Volume: 256 Suppl 1

    Topics: Antioxidants; Cardiomyopathies; Clinical Protocols; Clinical Trials as Topic; Dose-Response Relation

2009

Trials

2 trials available for idebenone and Cardiomyopathies

ArticleYear
Antioxidant use in Friedreich ataxia.
    Journal of the neurological sciences, 2008, Apr-15, Volume: 267, Issue:1-2

    Topics: Adolescent; Adult; Age Factors; Age of Onset; Antioxidants; Cardiomyopathies; Clinical Trials as Top

2008
Idebenone in patients with Friedreich ataxia.
    Neuroscience letters, 2001, Jun-29, Volume: 306, Issue:3

    Topics: Antioxidants; Benzoquinones; Cardiomyopathies; Cross-Over Studies; Echocardiography; Female; Friedre

2001

Other Studies

3 other studies available for idebenone and Cardiomyopathies

ArticleYear
Exonic deletions of FXN and early-onset Friedreich ataxia.
    Archives of neurology, 2012, Volume: 69, Issue:7

    Topics: Adult; Antioxidants; Cardiomyopathies; Disease Progression; Electromyography; Exons; Family Health;

2012
Effect of idebenone on cardiomyopathy in Friedreich's ataxia: a preliminary study.
    Lancet (London, England), 1999, Aug-07, Volume: 354, Issue:9177

    Topics: Adult; Antioxidants; Benzoquinones; Cardiac Volume; Cardiomyopathies; Child; Electron Transport Comp

1999
Dramatic improvement in mitochondrial cardiomyopathy following treatment with idebenone.
    Journal of inherited metabolic disease, 2001, Volume: 24, Issue:1

    Topics: Adult; Antioxidants; Benzoquinones; Biopsy; Cardiomyopathies; Electron Transport Complex I; Electron

2001