idebenone and Ataxia
idebenone has been researched along with Ataxia in 5 studies
Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Idebenone is a hydrophilic short-chain coenzyme (Co) Q analogue, which has been used as a potential bypass of defective complex I in both Leber Hereditary Optic Neuropathy and OPA1-dependent Dominant Optic Atrophy." | 1.48 | The idebenone metabolite QS10 restores electron transfer in complex I and coenzyme Q defects. ( Acosta Lopez, MJ; Argenton, F; Bernardi, P; Carelli, V; Carini, M; Da Ros, T; Galber, C; Giorgio, V; Petronilli, V; Prato, M; Salviati, L; Schiavone, M, 2018) |
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Giorgio, V | 1 |
| Schiavone, M | 1 |
| Galber, C | 1 |
| Carini, M | 1 |
| Da Ros, T | 1 |
| Petronilli, V | 1 |
| Argenton, F | 1 |
| Carelli, V | 1 |
| Acosta Lopez, MJ | 1 |
| Salviati, L | 1 |
| Prato, M | 1 |
| Bernardi, P | 1 |
| Kleiner, G | 1 |
| Barca, E | 1 |
| Ziosi, M | 1 |
| Emmanuele, V | 1 |
| Xu, Y | 1 |
| Hidalgo-Gutierrez, A | 1 |
| Qiao, C | 1 |
| Tadesse, S | 1 |
| Area-Gomez, E | 1 |
| Lopez, LC | 1 |
| Quinzii, CM | 1 |
| Hargreaves, IP | 1 |
| Schmitz-Hübsch, T | 1 |
| Klockgether, T | 1 |
| Cooper, JM | 1 |
| Schapira, AH | 1 |
Reviews
3 reviews available for idebenone and Ataxia
| Article | Year |
|---|---|
Coenzyme Q10 as a therapy for mitochondrial disease.
Topics: Animals; Ataxia; Humans; Mitochondrial Diseases; Molecular Structure; Muscle Weakness; Treatment Out | 2014 |
An update on inherited ataxias.
Topics: Antioxidants; Ataxia; Humans; Ubiquinone | 2008 |
Friedreich's ataxia: coenzyme Q10 and vitamin E therapy.
Topics: Animals; Ataxia; Benzoquinones; Coenzymes; Disease Models, Animal; Friedreich Ataxia; Humans; Iron; | 2007 |
Other Studies
2 other studies available for idebenone and Ataxia
| Article | Year |
|---|---|
The idebenone metabolite QS10 restores electron transfer in complex I and coenzyme Q defects.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Ataxia; Cell Respiration; Cells, Cultured; Electron T | 2018 |
CoQ
Topics: Alkyl and Aryl Transferases; Animals; Antioxidants; Ataxia; Disease Models, Animal; HeLa Cells; Huma | 2018 |