Page last updated: 2024-08-23

idazoxan and Muscle Contraction

idazoxan has been researched along with Muscle Contraction in 65 studies

*Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments. [MeSH]

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	30 (46.15)	18.7374
1990's	28 (43.08)	18.2507
2000's	5 (7.69)	29.6817
2010's	1 (1.54)	24.3611
2020's	1 (1.54)	2.80

Authors

Authors	Studies
Lattimer, N; Rhodes, KF; Sharma, S; Ward, TJ; Waterfall, JF; White, JF	1
Butler, RC; Chapleo, CB; Davis, JA; Doxey, JC; England, CD; Myers, M; Myers, PL; Stillings, MR; Tweddle, N; Welbourn, AP	1
England, CD; Smith, CF; Stillings, MR; Welbourn, AP	1
Harsing, LG; Somogyi, GT; Szabo, L; Szantay, C; Toth, I; Vizi, ES	1
Alexander, EJ; Bailey, DM; Castaldi, MJ; Ferrari, RA; Haubrich, DR; Luttinger, DA; Perrone, MH; Wentland, MP	1
Anderson, PS; Guare, JP; Halczenko, W; Huff, JR; Hunt, CA; King, SW; Lotti, VJ; Randall, WC; Saari, WS; Taylor, DA	1
Giannella, M; Marucci, G; Melchiorre, C; Piergentili, A; Pigini, M; Quaglia, W; Tayebati, SK	1
Antunes, E; Britto-Júnior, J; Campos, R; De Nucci, G; Ferreira-Novaes Silva, LP; Fregonesi, A; Gião, AA; Lima, AT; Mendes, GD; Pupo, AS	1
Acheson, AG; Dashwood, MR; Eames, T; Gruss, H; Henry, Y; Rayment, SJ; Scholefield, JH; Simpson, JA; Wilson, VG	1
Artigues-Varin, C; Mulder, P; Richard, V; Thuillez, C; Varin, R	1
Garcez-do-Carmo, L; Jurkiewicz, A; Piçarro, I; Santos, WC; Smaili, SS	1
Aricioglu, F; Dulger, G; Ercil, E	1
Aricioglu, F; Utkan, T	1
Nechifor, M; Serban, DN; Serban, IL	1
Dabiré, H; Dausse, JP; Meyer, P; Mouillé, P; Schmitt, H	1
Doxey, JC; Roach, AG; Smith, CF	1
Doxey, JC; Lane, AC; Roach, AG; Virdee, NK	1
Langer, SZ; Medgett, IC	2
Doxey, JC; Roach, AG; Strachan, DA; Virdee, NK	1
Dabiré, H; Mouillé, P; Schmitt, H	2
Blaylock, NA; Kendall, DA; Wilson, VG; Wright, IK	1
Aston, N; Chess-Williams, R; Couldwell, C	1
Baez, M; Cohen, ML; Cushing, DJ; Kursar, JD; Schenck, K	1
Pennefather, JN; Ventura, S	1
Feller, DR; Kerezy, A; Lei, L; Miller, DD; Patil, PN; Slavica, M	1
Kulkarni, SK; Sharma, A	1
Blandizzi, C; Carignani, D; Colucci, R; Crema, F; Del Tacca, M; Lazzeri, G; Natale, G	1
Clarke, DE; Ford, AP; Lachnit, WG	1
Boulanger, CM; Illiano, S; Marsault, R; Taddei, S; Vanhoutte, PM	1
Avellar, MC; Markus, RP	1
Brock, JA; McLachlan, EM; Rayner, SE	1
Furukawa, T; Morishita, H	1
Coupar, IM; Liu, L	1
Goldstein, I; Huang, YH; Moreland, RB; Traish, AM	1
Burian, M; Donecker, K; Göthert, M; Molderings, GJ; Schröder, DW; Simon, WA	1
Najbar-Kaszkiel, AT; Rand, MJ	1
Mason, R; Mundey, MK; Wilson, VG	1
Nott, MW; Rand, MJ; Thaina, P	1
Muir, TC; Nally, JE	1
Harsing, LG; Vizi, ES	1
Candura, SM; Coccini, T; Costa, LG; Manzo, L; Marraccini, P; Rossi, A; Tonini, M	1
Ogidigben, MJ; Potter, DE	1
Bültmann, R; Starke, K; von Kügelgen, I	1
Marshall, IG; Prior, C; Wannan, G	1
Angel, I; Langer, SZ	1
Dettmar, PW; Kelly, J; MacDonald, A	1
Hall, MT; Hamilton, CA; Kane, KA; Reid, JL; Rodger, IW; Wadsworth, RM	1
Calvete, J; Hayes, R; Sever, PS; Thom, S	1
Buckingham, RE; Clapham, JC; Cooper, SM; Wilson, C	1
Leighton, HJ; Ramagopal, MV	1
Kenakin, TP; Novak, PJ	1
Downing, OA; Stein, W; Wilson, KA; Wilson, VG	1
Calvete, J; Hayes, R; Martin, G; Sever, P; Thom, S	1
Doxey, JC; Roach, AG; Samuel, J	1
Lattimer, N; Rhodes, KF; Waterfall, JF	1
Hicks, PE; Langer, SZ; Macrae, AD	1
Greenwood, B; Read, NW	1
Schilling, L; Wahl, M	1
Broadley, KJ; Williamson, KL	1
Pittner, H	1
Rhodes, KF; Waterfall, JF	1
Brasili, L; Cassinelli, A; Giardinà, D; Gulini, U; Melchiorre, C; Quaglia, W	1
Amobi, N; Smith, IC	1

Trials

1 trial(s) available for idazoxan and Muscle Contraction

Article	Year
Human vascular smooth muscle responses mediated by alpha 2 mechanisms in vivo and in vitro. Clinical science (London, England : 1979), 1985, Volume: 68 Suppl 10 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Arteries; Brimonidine Tartrate; Dioxanes; Doxazosin; Forearm; Humans; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha	1985

Article

Year

Human vascular smooth muscle responses mediated by alpha 2 mechanisms in vivo and in vitro.

Clinical science (London, England : 1979), 1985, Volume: 68 Suppl 10

Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Arteries; Brimonidine Tartrate; Dioxanes; Doxazosin; Forearm; Humans; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha

1985

Other Studies

64 other study(ies) available for idazoxan and Muscle Contraction

Article	Year
Synthesis and structure-activity relationships of 2-sulfonamido-1,3,4,6,7,11b alpha-hexahydro-2H-benzo[a]quinolizines as alpha 2-adrenoceptor antagonists. Journal of medicinal chemistry, 1988, Volume: 31, Issue:7 Topics: Animals; Chemical Phenomena; Chemistry; Clonidine; Dioxanes; Idazoxan; Male; Methoxamine; Molecular Conformation; Muscle Contraction; Muscles; Quinolizines; Rats; Receptors, Adrenergic, alpha; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Vas Deferens; Yohimbine	1988
Alpha-adrenoreceptor reagents. 3. Synthesis of some 2-substituted 1,4-benzodioxans as selective presynaptic alpha 2-adrenoreceptor antagonists. Journal of medicinal chemistry, 1985, Volume: 28, Issue:8 Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dioxins; Idazoxan; In Vitro Techniques; Male; Mice; Muscle Contraction; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Synapses; Vas Deferens	1985
Effect of methoxy substitution on the adrenergic activity of three structurally related alpha 2-adrenoreceptor antagonists. Journal of medicinal chemistry, 1986, Volume: 29, Issue:9 Topics: Adrenergic alpha-Antagonists; Animals; Chemical Phenomena; Chemistry; Clonidine; Dioxanes; Dioxins; Imidazoles; Male; Mice; Muscle Contraction; Phenylephrine; Piperidines; Piperoxan; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Structure-Activity Relationship	1986
Berbanes: a new class of selective alpha 2-adrenoceptor antagonists. Journal of medicinal chemistry, 1987, Volume: 30, Issue:8 Topics: Adrenergic alpha-Antagonists; Alkaloids; Animals; Berberine Alkaloids; Chemical Phenomena; Chemistry; Dioxanes; Guinea Pigs; Idazoxan; Ileum; Male; Muscle Contraction; Phentolamine; Prazosin; Pulmonary Artery; Rabbits; Rats; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine	1987
Synthesis and antidepressant properties of novel 2-substituted 4,5-dihydro-1H-imidazole derivatives. Journal of medicinal chemistry, 1987, Volume: 30, Issue:8 Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Chemical Phenomena; Chemistry; Dioxanes; Dopamine; Idazoxan; Imidazoles; Male; Mice; Muscle Contraction; Muscle, Smooth; Norepinephrine; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Structure-Activity Relationship; Tetrabenazine	1987
Pyridinylpiperazines, a new class of selective alpha 2-adrenoceptor antagonists. Journal of medicinal chemistry, 1983, Volume: 26, Issue:12 Topics: Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Male; Muscle Contraction; Piperazines; Pupil; Pyridines; Rats; Vas Deferens; Yohimbine	1983
Structure-activity relationships in 1,4-benzodioxan-related compounds. 4. Effect of aryl and alkyl substituents at position 3 on alpha-adrenoreceptor blocking activity. Journal of medicinal chemistry, 1993, May-28, Volume: 36, Issue:11 Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rats; Stereoisomerism; Structure-Activity Relationship; Vas Deferens	1993
6-Nitrodopamine potentiates contractions of rat isolated vas deferens induced by noradrenaline, adrenaline, dopamine and electric field stimulation. Naunyn-Schmiedeberg's archives of pharmacology, 2023, Volume: 396, Issue:10 Topics: Animals; Catecholamines; Dopamine; Electric Stimulation; Epinephrine; Idazoxan; Male; Muscle Contraction; Norepinephrine; Rats; Receptors, Adrenergic; Vas Deferens	2023
Investigation of the distribution and function of alpha-adrenoceptors in the sheep isolated internal anal sphincter. British journal of pharmacology, 2010, Volume: 160, Issue:7 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anal Canal; Animals; Antibodies, Monoclonal; Autoradiography; Binding, Competitive; Dose-Response Relationship, Drug; Fecal Incontinence; Humans; Idazoxan; Immunohistochemistry; In Vitro Techniques; Muscle Contraction; Prazosin; Protein Binding; Radioligand Assay; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Sheep	2010
Alpha2-adrenoceptor ligands inhibit alpha1-adrenoceptor-mediated contraction of isolated rat arteries. Fundamental & clinical pharmacology, 2002, Volume: 16, Issue:4 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Arteries; Azepines; Brimonidine Tartrate; Clonidine; Idazoxan; In Vitro Techniques; Ligands; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Oxazoles; Prostaglandins; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Rilmenidine; Yohimbine	2002
Dual effect of agmatine in the bisected rat vas deferens. The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:3 Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Agmatine; Animals; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Epididymis; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Potassium Chloride; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Drug; Sympathetic Nervous System; Synaptic Transmission; Vas Deferens; Yohimbine	2003
Agmatine inhibits naloxone-induced contractions in morphine-dependent Guinea pig ileum. Annals of the New York Academy of Sciences, 2003, Volume: 1009 Topics: Adrenergic alpha-Antagonists; Agmatine; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Idazoxan; Ileum; Male; Morphine; Morphine Dependence; Muscle Contraction; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome; Yohimbine	2003
Inhibitory effect of harmane on morphine-dependent Guinea pig ileum. Annals of the New York Academy of Sciences, 2003, Volume: 1009 Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Guinea Pigs; Harmine; Idazoxan; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscle Contraction; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome; Yohimbine	2003
Idazoxan effects upon contractile activity in the rat aorta are related to alpha adrenoceptors and L-type channels. Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:6 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Endothelium, Vascular; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vasoconstrictor Agents	2004
In vitro studies with (imidazolinyl-2)-2-benzodioxane-1-4 ((+/-)-170 150), a new potent alpha 2-adrenoceptor blocking agent. European journal of pharmacology, 1982, Dec-17, Volume: 86, Issue:1 Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brain; Clonidine; Dioxins; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine	1982
Studies on RX 781094: a selective, potent and specific antagonist of alpha 2-adrenoceptors. British journal of pharmacology, 1983, Volume: 78, Issue:3 Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Dioxins; Dose-Response Relationship, Drug; Guinea Pigs; Idazoxan; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tyramine; Vas Deferens; Vasoconstriction; Yohimbine	1983
Comparison of the alpha-adrenoceptor antagonist profiles of idazoxan (RX 781094), yohimbine, rauwolscine and corynanthine. Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 325, Issue:2 Topics: Adrenergic alpha-Antagonists; Animals; Brain; Cocaine; Decerebrate State; Dioxins; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Membranes; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Inbred Strains; Vas Deferens; Yohimbine	1984
Heterogeneity of smooth muscle alpha adrenoceptors in rat tail artery in vitro. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Electric Stimulation; Idazoxan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Yohimbine	1984
Selectivity and potency of 2-alkyl analogues of the alpha 2-adrenoceptor antagonist idazoxan (RX 781094) in peripheral systems. British journal of pharmacology, 1984, Volume: 83, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dioxanes; Dioxins; Electric Stimulation; Heart Rate; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Muscles; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Vas Deferens; Yohimbine	1984
Action of stereoisomers of (imidazolinyl-2)-2-benzodioxane-1-4 or 2-(2-(1,4-benzodioxanyl))-2-imidazoline (170 150; RX 781094) on peripheral presynaptic and central alpha 2-adrenoceptors. European journal of pharmacology, 1982, Dec-17, Volume: 86, Issue:1 Topics: Animals; Brain; Chickens; Clonidine; Dioxins; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Peripheral Nerves; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sleep; Stereoisomerism; Vas Deferens	1982
Characterisation of smooth muscle alpha-adrenoceptors and of responses to electrical stimulation in the cat isolated perfused middle cerebral artery. Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 323, Issue:1 Topics: Animals; Cats; Cerebral Arteries; Dioxins; Electric Stimulation; Female; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Prazosin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vasodilator Agents	1983
The relationship between density of alpha-adrenoceptor binding sites and contractile responses in several porcine isolated blood vessels. British journal of pharmacology, 1995, Volume: 114, Issue:3 Topics: 5'-Nucleotidase; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Cell Membrane; Dioxanes; Dose-Response Relationship, Drug; Drug Interactions; Ear, External; Idazoxan; Male; Microscopy, Electron; Muscle Contraction; Muscle, Smooth, Vascular; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha; Splenic Artery; Structure-Activity Relationship; Swine; Veins; Yohimbine	1995
Alpha 1A-adrenoceptor subtype mediates contraction of the rat urethra. Journal of autonomic pharmacology, 1994, Volume: 14, Issue:6 Topics: Aminoquinolines; Animals; Calcium; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Tetrahydroisoquinolines; Urethra	1994
Serotonin-induced contraction in canine coronary artery and saphenous vein: role of a 5-HT1D-like receptor. Life sciences, 1994, Volume: 54, Issue:22 Topics: 5-Methoxytryptamine; Adrenergic alpha-Antagonists; Animals; Base Sequence; Blotting, Southern; Coronary Vessels; Dioxanes; DNA Primers; Dogs; Dose-Response Relationship, Drug; Gene Expression; Idazoxan; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth, Vascular; Piperazines; Polymerase Chain Reaction; Prazosin; Receptors, Serotonin; RNA, Messenger; Saphenous Vein; Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines	1994
Alpha 2-adrenoceptor binding sites vary along the length of the male reproductive tract: a possible basis for the regional variation in response to field stimulation. European journal of pharmacology, 1994, Mar-11, Volume: 254, Issue:1-2 Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Dioxanes; Electric Stimulation; Epididymis; Idazoxan; In Vitro Techniques; Male; Membranes; Muscle Contraction; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vas Deferens; Yohimbine	1994
Synthesis and biological activities of a new set of irreversibly acting 2-(4'-isothiocyanatobenzyl)imidazoline analogs in rat thoracic aorta. Journal of medicinal chemistry, 1994, Jun-10, Volume: 37, Issue:12 Topics: Animals; Aorta, Thoracic; Calcium Channels; Dioxanes; Idazoxan; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Nifedipine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Tolazoline; Verapamil	1994
On the characterization of dopamine-induced contractile response of rat anococcygeus muscle preparation. Indian journal of experimental biology, 1994, Volume: 32, Issue:3 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Azepines; Benzazepines; Desipramine; Dioxanes; Dopamine; Female; Haloperidol; Idazoxan; Male; Muscle Contraction; Prazosin; Rats; Receptors, Adrenergic; Receptors, Dopamine; Reserpine; Sulpiride; Yohimbine	1994
Determination on functional basis of presynaptic alpha 2-adrenoceptor subtypes in guinea-pig duodenum. Neuroscience letters, 1996, May-24, Volume: 210, Issue:1 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cholinergic Fibers; Duodenum; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; Idazoxan; Imidazoles; Indoles; Isoindoles; Isoquinolines; Male; Medetomidine; Muscle Contraction; Nordefrin; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Receptors, Adrenergic, alpha-2; Synaptic Membranes; Vasoconstrictor Agents; Xylazine; Yohimbine	1996
SDZ NVI 085, an alpha 1A-adrenoceptor agonist with 5-HT2A receptor antagonist properties. European journal of pharmacology, 1996, Feb-15, Volume: 297, Issue:1-2 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bridged-Ring Compounds; Idazoxan; Ketanserin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Regional Blood Flow; Serotonin Antagonists; Tail	1996
Rilmenidine activates postjunctional alpha 1- and alpha 2-adrenoceptors in the canine saphenous vein. Fundamental & clinical pharmacology, 1996, Volume: 10, Issue:4 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium Channel Blockers; Clonidine; Dihydropyridines; Dogs; Female; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Isotope Labeling; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Osmolar Concentration; Oxazoles; Phenoxybenzamine; Prazosin; Protein Binding; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Saphenous Vein; Tritium; Yohimbine	1996
Are imidazoline receptors involved in sympathetic neurotransmission in rat vas deferens? General pharmacology, 1996, Volume: 27, Issue:7 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Idazoxan; Imidazoline Receptors; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Oxazoles; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Sympathetic Nervous System; Synaptic Transmission; Vas Deferens; Yohimbine	1996
Contribution of alpha-adrenoceptors to depolarization and contraction evoked by continuous asynchronous sympathetic nerve activity in rat tail artery. British journal of pharmacology, 1997, Volume: 120, Issue:8 Topics: Adrenergic alpha-Antagonists; Animals; Arteries; Calcium Channel Blockers; Ciguatoxins; Female; Idazoxan; Membrane Potentials; Muscle Contraction; Nifedipine; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic, alpha; Tail	1997
Existence of dopamine D1 receptor on the sympathetic nerve endings in the guinea-pig vas deferens. European journal of pharmacology, 1997, Jun-11, Volume: 328, Issue:2-3 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Brimonidine Tartrate; Dopamine Agonists; Dopamine Antagonists; Electric Stimulation; Guinea Pigs; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Presynaptic Terminals; Quinoxalines; Receptors, Dopamine D1; Spiperone; Synaptic Transmission; Vas Deferens	1997
Characterisation of pre- and post-synaptic alpha-adrenoceptors in modulation of the rat ileum longitudinal and circular muscle activities. Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Brimonidine Tartrate; Clonidine; Electric Stimulation; Idazoxan; Ileum; In Vitro Techniques; Muscle Contraction; Oxymetazoline; Phentolamine; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Receptors, Presynaptic	1997
Expression of functional alpha2-adrenergic receptor subtypes in human corpus cavernosum and in cultured trabecular smooth muscle cells. Receptors & signal transduction, 1997, Volume: 7, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Binding, Competitive; Brimonidine Tartrate; Cells, Cultured; Colforsin; Cyclic AMP; Humans; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Penis; Quinoxalines; Radioisotopes; Receptors, Adrenergic, alpha-2; Ribonucleases; RNA, Messenger; Yohimbine	1997
Characterization of I2 imidazoline and sigma binding sites in the rat and human stomach. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:1 Topics: Adrenergic alpha-Antagonists; Aminopyrine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Binding Sites; Female; Gastric Fundus; Gastric Mucosa; Guanidines; Humans; Idazoxan; Male; Muscle Contraction; Rabbits; Rats; Rats, Inbred WKY; Stomach	1998
Effects of P2-receptor agonists on sympathetic neuroeffector transmission in the rat isolated anococcygeus muscle. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:5 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Desipramine; Electric Stimulation; Enzyme Inhibitors; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; NADP; NG-Nitroarginine Methyl Ester; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Synaptic Transmission; Thionucleotides	1998
Selective potentiation by ouabain of naloxone-induced withdrawal contractions of isolated guinea-pig ileum following acute exposure to morphine. British journal of pharmacology, 1998, Volume: 124, Issue:5 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carbachol; Clonidine; Drug Synergism; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Idazoxan; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Naloxone; Narcotic Antagonists; Ouabain; Receptors, Adrenergic, alpha-2; Sodium-Potassium-Exchanging ATPase; Substance Withdrawal Syndrome	1998
Effects of some imidazolidine alpha2-adrenoceptor agonists in rat isolated atria. Journal of autonomic pharmacology, 1999, Volume: 19, Issue:3 Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Clonidine; Drug Interactions; Electric Stimulation; Female; Heart Atria; Heart Rate; Idazoxan; Imidazoles; In Vitro Techniques; Muscle Contraction; Norepinephrine; Pargyline; Prazosin; Quinoxalines; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Time Factors	1999
The electrical and mechanical responses of the rabbit saphenous artery to nerve stimulation and drugs. British journal of pharmacology, 1992, Volume: 105, Issue:2 Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Arteries; Dioxanes; Electric Stimulation; Electrophysiology; Evoked Potentials; Idazoxan; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Neuromuscular Junction; Norepinephrine; Phospholipids; Prazosin; Rabbits; Suramin; Sympathetic Nervous System	1992
Different sites of action for alpha 2-adrenoceptor antagonists in the modulation of noradrenaline release and contraction response in the vas deferens of the rat. The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Berberine; Chromatography, High Pressure Liquid; Dioxanes; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rats; Rats, Inbred Strains; Vas Deferens; Xylazine; Yohimbine	1992
Calcium entry blockade as a mechanism for chlordimeform-induced inhibition of motor activity in the isolated guinea-pig ileum. Pharmacology & toxicology, 1992, Volume: 71, Issue:6 Topics: Adrenergic alpha-Antagonists; Animals; Chlorphenamidine; Clonidine; Dioxanes; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; Idazoxan; Ileum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Peristalsis	1992
Medetomidine-induced alterations of intraocular pressure and contraction of the nictitating membrane. Investigative ophthalmology & visual science, 1991, Volume: 32, Issue:10 Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cats; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Female; Idazoxan; Imidazoles; Intraocular Pressure; Male; Medetomidine; Muscle Contraction; Nictitating Membrane; Rabbits; Sympathectomy	1991
Contraction-mediating alpha 2-adrenoceptors in the mouse vas deferens. Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:6 Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Dioxanes; Drug Interactions; Idazoxan; Male; Mice; Muscle Contraction; Neuropeptide Y; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Suramin; Vas Deferens; Yohimbine	1991
Alpha-adrenoceptor blocking properties of vesamicol. European journal of pharmacology, 1991, Aug-16, Volume: 201, Issue:1 Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Corticosterone; Desipramine; Dioxanes; Electric Stimulation; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stereoisomerism; Vas Deferens	1991
Pre- and postsynaptic alpha-2 adrenoceptors as target for drug discovery. Journal of neural transmission. Supplementum, 1991, Volume: 34 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Dioxanes; Dogs; Hyperglycemia; Hypoglycemic Agents; Hypothalamus; Idazoxan; In Vitro Techniques; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Norepinephrine; Pyrroles; Rats; Receptors, Adrenergic, alpha; Synapses	1991
Pre- and post-junctional alpha-adrenoceptor-mediated responses in the rat gastric fundus in-vitro. The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:11 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cholinergic Fibers; Dioxanes; Electric Stimulation; Gastric Fundus; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Prazosin; Rats; Rats, Inbred Strains	1990
Noradrenaline sensitivity and calcium fluxes in arteries from rabbits with perinephritis hypertension. Clinical and experimental pharmacology & physiology, 1990, Volume: 17, Issue:8 Topics: Angiotensin II; Animals; Aorta; Calcium; Cocaine; Dioxanes; Hypertension, Renovascular; Idazoxan; Kidney; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Norepinephrine; Potassium Chloride; Prazosin; Rabbits; Time Factors	1990
(Imidazolinyl-2)-2-benzodioxane 1-4 (idazoxan) and its stereoisomers, new alpha 2-antagonists. Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 6 Topics: Animals; Azepines; Chickens; Clonidine; Dioxanes; Dioxins; Heart Rate; Idazoxan; Imidazoles; Male; Mice; Muscle Contraction; Rats; Receptors, Adrenergic, alpha; Stereoisomerism; Structure-Activity Relationship; Vas Deferens	1985
In vivo and in vitro studies of alpha 2-adrenoceptor responses in human vascular smooth muscle. Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 6 Topics: Adult; Animals; Arm; Brimonidine Tartrate; Dioxanes; Dioxins; Doxazosin; Epinephrine; Humans; Idazoxan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Regional Blood Flow; Vasomotor System	1985
Alpha 1-adrenoceptor-mediated contraction of rabbit mesenteric artery: a role for intra- and extracellular calcium pools. Journal of cardiovascular pharmacology, 1987, Volume: 9, Issue:4 Topics: Animals; Calcium; Dioxanes; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha	1987
Analysis of the presence of postjunctional alpha-2 adrenoceptors in the rat anococcygeus muscle. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:2 Topics: Animals; Clonidine; Dioxanes; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Phenoxybenzamine; Prazosin; Rats; Receptors, Adrenergic, alpha; Regression Analysis	1989
Classification of phenoxybenzamine/prazosin-resistant contractions of rat spleen to norepinephrine by Schild analysis: similarities and differences to postsynaptic alpha-2 adrenoceptors. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:1 Topics: Alkylation; Animals; Dioxanes; Drug Resistance; Idazoxan; Male; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Spleen; Yohimbine	1988
A comparison of the actions of noradrenaline and UK-14,304 in the longitudinal smooth muscle of the rat isolated portal vein--no evidence for a population of post-junctional alpha 2-adrenoceptors. Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:3 Topics: Animals; Brimonidine Tartrate; Dioxanes; Idazoxan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Portal Vein; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha	1988
Effects of desipramine on stimulation-induced contractions of the vas deferens of rats pretreated either chronically with desipramine or acutely with idazoxan. Clinical science (London, England : 1979), 1985, Volume: 68 Suppl 10 Topics: Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Desipramine; Dioxanes; Dioxins; Drug Interactions; Electric Stimulation; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Time Factors; Vas Deferens	1985
Studies of alpha 2-adrenoceptor antagonist potency in vitro: comparisons in tissues from rats, rabbits, dogs and humans. Clinical science (London, England : 1979), 1985, Volume: 68 Suppl 10 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; Dioxanes; Dogs; Humans; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Platelet Aggregation; Quinolizines; Rabbits; Rats; Rats, Inbred Strains; Saphenous Vein; Species Specificity; Vas Deferens; Yohimbine	1985
Differential blocking actions of idazoxan against the inhibitory effects of 6-fluoronoradrenaline and clonidine in the rat vas deferens. British journal of pharmacology, 1985, Volume: 86, Issue:1 Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Cocaine; Dioxanes; Dioxins; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Pargyline; Rats; Reserpine; Vas Deferens	1985
Neural control of jejunal and ileal motility and transmural potential difference in the ferret. Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine; Brimonidine Tartrate; Dioxanes; Ferrets; Gastrointestinal Motility; Idazoxan; Ileum; In Vitro Techniques; Jejunum; Male; Membrane Potentials; Muscle Contraction; Quinoxalines	1986
Antagonism of bencianol (ZY 15051) and idazoxan (RX 781094) to norepinephrine in feline pial arteries in situ. Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 280, Issue:2 Topics: Adrenergic alpha-Antagonists; Animals; Arteries; Cats; Dioxanes; Dioxins; Female; Flavonoids; Idazoxan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride	1986
Characterization of the alpha-adrenoceptors mediating positive inotropy of rat left atria by use of selective agonists and antagonists. Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 285, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Brimonidine Tartrate; Dioxanes; Idazoxan; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Muscle Contraction; Myocardial Contraction; Phenylephrine; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stimulation, Chemical	1987
Does the beta 1-adrenoceptor blocking agent celiprolol have alpha 2-adrenoceptor blocking properties? Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 285, Issue:2 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Blood Pressure; Celiprolol; Decerebrate State; Dioxanes; Heart; Heart Rate; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myocardium; Propanolamines; Rats; Rats, Inbred Strains	1987
The effects of some alpha-adrenoceptor antagonists on the responses of the canine saphenous vein to B-HT 933, UK-14304 and methoxamine. Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 335, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Brimonidine Tartrate; Dioxanes; Dogs; Idazoxan; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Potassium Chloride; Quinoxalines; Saphenous Vein	1987
Alpha-adrenoceptor occupancy by N,N-dimethyl-2-bromo-2-phenethylamine hydrobromide (DMPEA) in rat vas deferens. European journal of pharmacology, 1988, Aug-24, Volume: 153, Issue:2-3 Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Phenethylamines; Rats; Receptors, Adrenergic, alpha; Thiosulfates; Vas Deferens	1988
Effects of alpha,beta-methylene ATP on biphasic responses of rat vas deferens. European journal of pharmacology, 1987, Jan-06, Volume: 133, Issue:1 Topics: Adenosine Triphosphate; Animals; Dioxanes; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Rats; Receptors, Adrenergic; Receptors, Purinergic; Theophylline; Vas Deferens	1987