Page last updated: 2024-08-23

idarubicin and Leukemia

idarubicin has been researched along with Leukemia in 86 studies

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-199024 (27.91)18.7374
1990's25 (29.07)18.2507
2000's26 (30.23)29.6817
2010's11 (12.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blijlevens, NMA; Kox, M; Leijte, GP; Pickkers, PP; Scheffer, GJ; Timmermans, K1
Fang, J; Li, J; Lu, X; Shi, W; Wang, H; Wu, Q; Xia, L; You, Y; Zang, S; Zhang, C; Zhang, R; Zhong, Z1
Farooq, A; Farooq, MU; Khan, DH; Mir, MA; Mushtaq, F1
Arioka, Y; Funato, T; Hara, T; Kawasoe, M; Markey, SP; Matsunami, H; Moriwaki, H; Okawa, K; Saito, K; Takeda, M; Takemura, M; Tsurumi, H; Yamamoto, Y1
Hu, C; Jin, J; Li, K; Mei, C; Ren, Z; Tong, H; Vera, JC; Zhuang, Z1
Kotsianidis, I; Tsatalas, C1
Hong, M; Li, JY; Qian, SX; Qiu, HX; Wu, HX; Xu, W; Zhang, R1
Chen, ZC; Li, L; Li, QB; Xia, LH; You, Y; Zou, P1
Akutsu, M; Furukawa, Y; Izumi, T; Kano, Y; Mano, H; Miyawaki, S; Tanaka, M; Tsunoda, S; Yazawa, Y1
Dong, X; Gupte, A; Ledebur, HC; Leggas, M; Ma, P; Mumper, RJ; Swadley, CL1
Egorin, MJ; Espinoza-Delgado, I; Ferrajoli, A; Garcia-Manero, G; Holleran, JL; Kadia, TM; Kantarjian, HM; Madden, TL; Maddipotti, S; Newsome, W; Ravandi, F; Sanchez-Gonzalez, B; Schroeder, C; Thomas, DA; Yang, H; Zwiebel, JA1
Hsu, CH; Liu, CI1
Hu, M; Jiang, H; Xia, M1
Kutner, A; Maciejewska, M; Nasulewicz-Goldeman, A; Opolska, A; Switalska, M; Wietrzyk, J1
Chen, L; Ding, Y; Wang, Y; Yan, W1
Giles, FJ1
Balduzzi, A; Biondi, A; Bonanomi, S; Dassi, M; Gaipa, G; Perseghin, P; Rovelli, A; Uderzo, C1
Błasiak, J; Drzewoski, J; Gloc, E; Młynarski, W; Skórski, T1
Barge, RM; Honders, MW; Spoelder, HE; Veuger, MJ; Willemze, R1
Qi, SN; Ueda, T; Yoshida, A1
Crivellari, D; Lombardi, D; Spazzapan, S; Toffoli, G; Veronesi, A1
Burnett, AK; Milligan, DW; Wheatley, K1
Bauer, KS; Garimella, TS; Karp, JE; Ross, DD; Tan, M; Wu, S1
Seiter, K1
Bueso-Ramos, C; Garcia-Manero, G; Hoshino, K; Quintas-Cardama, A; Richon, VM; Sanchez-Gonzalez, B; Yang, H1
Akutsu, M; Furukawa, Y; Izumi, T; Kano, Y; Kirito, K; Mano, H; Matsuo, Y; Odgerel, T; Sato, Y; Tsunoda, S; Vu, HA1
Adams, DJ; Giles, F; Jacobsen, TF; Myhren, F; Rizzieri, DA; Sandvold, ML1
Lambertenghi-Deliliers, G; Maiolo, AT; Pacciarini, MA; Pogliani, E; Polli, EE1
Carde, P; Chahine, G; Hayat, M; Hurteloup, P; Kamioner, D; Parmentier, C; Pico, JO; Schlumberger, M1
Barron, JT; Ghalie, R; Kaizer, H; Kakavas, PW; Parrillo, JE1
Ariyoshi, Y; Ogawa, M1
de Witte, T; Dompeling, E; Donnelly, P; Linssen, P; Minderman, H; Muus, P; Schattenberg, A1
Robak, T1
Fukushima, T; Nakamura, T; Uchida, M; Ueda, T1
Hegewisch-Becker, S; Hossfeld, DK1
Ueda, T1
Tamura, K1
Baguley, BC; Davey, MW; Davey, RA; Hargrave, RM; Harvie, RM; Su, GM1
Belloc, F; Bernard, P; Besnard, S; Boisseau, MR; Dumain, P; Lacombe, F; Reiffers, J; Vial, JP1
Buckley, MM; Lamb, HM1
Avramis, VI; Dinndorf, PA; Kelleher, JF; Krailo, MD; Liu-Mares, W; Mosher, RB; Reaman, GH; Sato, JK; Seibel, NL; Wiersma, S1
Faussat, AM; Marie, JP; Simonin, G; Zhou, DC; Zittoun, R1
Brieden, T; Gieseler, F; Kunze, J; Nüssler, V; Valsamas, S1
Garnier-Suillerot, A; Mankhetkorn, S1
Camera, A; Catalano, L; Picardi, M; Rotoli, B; Selleri, C1
Barbui, T; Bassan, R; Chiodini, B1
Davey, MW; Davey, RA; Locke, VL1
Gieseler, F; Kessel, M; Woodcock, BG1
Fumihara, T; Nagasawa, K; Ohnishi, N; Yokoyama, T1
Darbyshire, P; Lawson, S; Williams, M1
Mandelli, F; Montefusco, E1
Bascans, E; Belaud-Rotureau, MA; Belloc, F; Braz-Pereira, E; Durrieu, F; Lacombe, F; Lavignolle, V1
Kim, S; Kim, SH; Kim, WK; Lee, JH; Lee, JS; Lee, KH; Seol, M1
Craddock, C; Garg, M; Lawler, M; Pawson, R; Potter, MN; Prentice, HG; Rassam, S; Rezvani, K; Theocharous, P; Yin, JA1
Arcese, W; Cerretti, R; De Felice, L; Donato, V; Fenu, S; Guglielmi, C; Iori, A; Laurenti, L; Mengarelli, A; Micozzi, A; Romano, A; Torromeo, C1
Lotfi, K; Peterson, C; Zackrisson, AL1
Barbui, T; Bassan, R; Borleri, G; Buelli, M; Chiodini, B; Lerede, T; Rambaldi, A; Rossi, A; Viero, P1
Aleskog, A; Höglund, M; Jonsson, E; Kristensen, J; Larsson, R; Nygren, P; Sundström, C1
Austin, CA; Errington, F; Tilby, MJ; Willmore, E1
Fantasia, JE; Kaplan, R; Wu, J1
Daenen, SM; Kluin-Nelemans, JC; van Spronsen, DJ1
Fujita, H; Kimura, K; Masaoka, T; Ogawa, M; Yamada, K1
Fields, SM; Koeller, JM1
Ames, MM; Hammond, GD; Krailo, MD; Pendergrass, TW; Reid, JM1
Carella, AM; D'Amico, T; Damasio, E; Gaozza, E; Giordano, D; Nati, S; Piatti, G; Pungolino, E; Spriano, M1
Arlin, ZA1
Haanen, C; Minderman, H; Speth, PA1
Arlin, ZA; Berman, E; Clarkson, BD; Daghestani, A; Gee, TS; Hancock, C; Kempin, S; Raymond, V; Stevens, YW; Williams, L1
Mandelli, F; Petti, MC1
Andreeff, M; Berman, E; Gabrilove, J; Gee, T; Gulati, S; Heller, G; Kempin, SJ; Kolitz, J; Raymond, V; Young, CW1
Raymond, V; Young, CW1
Alpert, BS; de Graaf, SS; Dow, LW; Evans, WE; Murphy, SB; Pui, CH; Rodman, JH1
Annaloro, C; Lambertenghi-Deliliers, G; Pacciarini, MA; Pogliani, E; Polli, EE1
Coccia-Portugal, MA; Dreyer, R; Falkson, G; Terblanche, AP; Vorobiof, DA1
Haanen, C; Linssen, PC; Speth, PA; van de Loo, FA; Wessels, HM1
Bacha, DM; Dantis, E; Hancock, C; Luks, E; Meyers, P; Mondora, A; Steinherz, L; Steinherz, P; Tan, CT; Winick, N1
Annaloro, C; Cortelezzi, A; Ganzina, F; Lambertenghi-Deliliers, G; Maiolo, AT; Pogliani, E; Polli, EE1
Carella, AM; Cerri, R; Congiu, A; Damasio, E; Gaozza, E; Giordano, D; Martinengo, M; Nati, S; Risso, M; Santini, G1
Di Pietro, N; Ganzina, F; Pacciarini, MA1
Arlin, ZA; Baratz, R; Budman, D; Daghestani, AN; Gee, TS; Kempin, SJ; Leyland-Jones, B; Mertelsmann, R; Schulman, P; Williams, L1
Carella, AM; Cerri, R; Congiu, A; Damasio, E; Giordano, D; Martinengo, M; Nati, S; Risso, M; Rossi, E; Santini, G1
Eridani, S; Pearson, TC; Singh, AK; Slater, NG1
Carella, AM; Cerri, R; Congiu, A; Frassoni, F; Giordano, D; Marmont, A; Martinengo, M; Nati, S; Risso, M; Santini, G1
Cavalli, F; Fopp, M; Sessa, C; Tschopp, L1
Bayle, C; Berger, R; Carde, P; Finaud, M; Hayat, M; Hurteloup, P; Morardet, N; Parmentier, C; Schlumberger, M1

Reviews

15 review(s) available for idarubicin and Leukemia

ArticleYear
Troxacitabine-based therapy of refractory leukemia.
    Expert review of anticancer therapy, 2002, Volume: 2, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytarabine; Cytosine; Dioxolanes; Humans; Idarubicin; Leukemia; Remission Induction; Topotecan

2002
New oral drugs in older patients: a review of idarubicin in elderly patients.
    Critical reviews in oncology/hematology, 2004, Volume: 49, Issue:2

    Topics: Administration, Oral; Antibiotics, Antineoplastic; Breast Neoplasms; Female; Humans; Idarubicin; Leukemia; Lymphoma; Male

2004
Toxicity of the topoisomerase II inhibitors.
    Expert opinion on drug safety, 2005, Volume: 4, Issue:2

    Topics: Antineoplastic Agents; Cardiovascular Diseases; Daunorubicin; Doxorubicin; Enzyme Inhibitors; Epirubicin; Etoposide; Humans; Idarubicin; Leukemia; Middle Aged; Mitoxantrone; Mucositis; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors; Vascular Diseases

2005
[Clinical trials of new antitumor drugs in hematopoietic malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21 Suppl 3

    Topics: Acute Disease; Antineoplastic Agents, Phytogenic; Camptothecin; Clinical Trials as Topic; Doxorubicin; Ethics, Medical; Humans; Idarubicin; Irinotecan; Leukemia; Lymphoma

1994
[Clinical pharmacology of idarubicin].
    Acta haematologica Polonica, 1993, Volume: 24, Issue:4

    Topics: Animals; Biological Availability; Breast Neoplasms; Female; Humans; Idarubicin; Leukemia; Lymphoma

1993
The MDR phenotype in hematologic malignancies: prognostic relevance and future perspectives.
    Annals of hematology, 1996, Volume: 72, Issue:3

    Topics: Drug Resistance, Multiple; Forecasting; Gene Expression; Humans; Idarubicin; Leukemia; Lymphoma; Multiple Myeloma; Phenotype; Prognosis

1996
[Antileukemic agents--new drugs and attempts of rational administration].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:8

    Topics: Antineoplastic Agents; Drug Administration Schedule; Humans; Idarubicin; Leukemia; Vidarabine

1996
A phase I study of idarubicin hydrochloride in patients with acute leukemia. The Idarubicin Study Group of Japan.
    Seminars in hematology, 1996, Volume: 33, Issue:4 Suppl 3

    Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Area Under Curve; Bone Marrow Diseases; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Idarubicin; Japan; Leukemia; Male; Middle Aged; Molecular Structure

1996
Oral idarubicin. A review of its pharmacological properties and clinical efficacy in the treatment of haematological malignancies and advanced breast cancer.
    Drugs & aging, 1997, Volume: 11, Issue:1

    Topics: Antibiotics, Antineoplastic; Breast Neoplasms; Female; Humans; Idarubicin; Leukemia; Male

1997
[Treatment of acute and chronic leukemias].
    Recenti progressi in medicina, 1999, Volume: 90, Issue:11

    Topics: Acute Disease; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosome Aberrations; Combined Modality Therapy; Daunorubicin; Humans; Idarubicin; Karyotyping; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Randomized Controlled Trials as Topic; Transplantation, Autologous; Transplantation, Homologous

1999
Idarubicin: a second-generation anthracycline.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Drug Evaluation; Humans; Idarubicin; Leukemia; Neoplasms; Remission Induction

1991
Idarubicin in acute leukemia: an effective new therapy for the future.
    Seminars in oncology, 1989, Volume: 16, Issue:1 Suppl 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Forecasting; Humans; Idarubicin; Leukemia; Remission Induction

1989
Idarubicin v daunorubicin: preclinical and clinical pharmacokinetic studies.
    Seminars in oncology, 1989, Volume: 16, Issue:1 Suppl 2

    Topics: Animals; Cells, Cultured; Daunorubicin; Humans; Idarubicin; Leukemia; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice

1989
Clinical assessment of the structure-activity relationship of anthracyclines and related synthetic derivatives.
    Cancer treatment reports, 1986, Volume: 70, Issue:1

    Topics: Aclarubicin; Anthraquinones; Antibiotics, Antineoplastic; Breast Neoplasms; Carubicin; Cell Survival; Daunorubicin; Doxorubicin; Drug Evaluation; Epirubicin; Heart; Humans; Idarubicin; Leukemia; Menogaril; Mitoxantrone; Naphthacenes; Nogalamycin; Sarcoma; Structure-Activity Relationship

1986
Idarubicin (4-demethoxydaunorubicin). A preliminary overview of preclinical and clinical studies.
    Investigational new drugs, 1986, Volume: 4, Issue:1

    Topics: Administration, Oral; Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Drug Evaluation, Preclinical; Humans; Idarubicin; Infusions, Parenteral; Kinetics; Leukemia

1986

Trials

11 trial(s) available for idarubicin and Leukemia

ArticleYear
[IDA-FLAG regimen in treatment of patients with refractory or relapsed acute leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2009, Volume: 17, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine

2009
A phase I study of vorinostat in combination with idarubicin in relapsed or refractory leukaemia.
    British journal of haematology, 2010, Volume: 150, Issue:1

    Topics: Acetylation; Acute Disease; Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cyclin-Dependent Kinase Inhibitor p21; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Female; Histones; Humans; Hydroxamic Acids; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Poly-ADP-Ribose Binding Proteins; Recurrence; RNA, Messenger; Vorinostat; Young Adult

2010
Peripheral blood stem cell collection in children with acute leukemia: effectiveness of the 'DIAVE' mobilizing regimen.
    Bone marrow transplantation, 2002, Volume: 30, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Child; Child, Preschool; Cytarabine; Dexamethasone; Etoposide; Graft Survival; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Idarubicin; Leukapheresis; Leukemia; Peripheral Blood Stem Cell Transplantation; Vincristine

2002
A phase I and pharmacologic study of idarubicin, cytarabine, etoposide, and the multidrug resistance protein (MDR1/Pgp) inhibitor PSC-833 in patients with refractory leukemia.
    Leukemia research, 2005, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclosporins; Cytarabine; Drug Interactions; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Idarubicin; Leukemia; Male; Maximum Tolerated Dose; Middle Aged; Treatment Outcome

2005
A phase I study of idarubicin hydrochloride in patients with acute leukemia. The Idarubicin Study Group of Japan.
    Seminars in hematology, 1996, Volume: 33, Issue:4 Suppl 3

    Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Area Under Curve; Bone Marrow Diseases; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Idarubicin; Japan; Leukemia; Male; Middle Aged; Molecular Structure

1996
Phase I/II study of idarubicin given with continuous infusion fludarabine followed by continuous infusion cytarabine in children with acute leukemia: a report from the Children's Cancer Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:8

    Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Idarubicin; Infant; Infusions, Intravenous; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine

1997
Use of idarubicin in pre-transplant conditioning in children with high-risk acute leukaemia.
    Bone marrow transplantation, 1999, Volume: 24, Issue:9

    Topics: Acute Disease; Adolescent; Antibiotics, Antineoplastic; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Digestive System; Female; Graft Survival; Graft vs Host Disease; Humans; Idarubicin; Infant; Leukemia; Male; Mouth Mucosa; Recurrence; Transplantation Conditioning; Transplantation, Homologous

1999
Phase I trial with escalating doses of idarubicin and multidrug resistance reversal by short-course cyclosporin A, sequential high-dose cytosine arabinoside, and granulocyte colony-stimulating factor for adult patients with refractory acute leukemia.
    Haematologica, 2002, Volume: 87, Issue:3

    Topics: Acute Disease; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Male; Maximum Tolerated Dose; Middle Aged; Salvage Therapy; Treatment Outcome

2002
Plasma pharmacokinetics and cerebrospinal fluid concentrations of idarubicin and idarubicinol in pediatric leukemia patients: a Childrens Cancer Study Group report.
    Cancer research, 1990, Oct-15, Volume: 50, Issue:20

    Topics: Adolescent; Adult; Child; Child, Preschool; Daunorubicin; Drug Evaluation; Humans; Idarubicin; Infant; Leukemia

1990
Idarubicin in acute leukemias: experience of the Italian Cooperative Group GIMEMA.
    Seminars in oncology, 1989, Volume: 16, Issue:1 Suppl 2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Random Allocation; Remission Induction

1989
Idarubicin in acute leukemia: results of studies at Memorial Sloan-Kettering Cancer Center.
    Seminars in oncology, 1989, Volume: 16, Issue:1 Suppl 2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction

1989

Other Studies

61 other study(ies) available for idarubicin and Leukemia

ArticleYear
Release of Danger-Associated Molecular Patterns following Chemotherapy Does Not Induce Immunoparalysis in Leukemia Patients.
    Acta haematologica, 2017, Volume: 138, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Biomarkers; Case-Control Studies; Cells, Cultured; Cholesterol, LDL; Cytarabine; Cytokines; DNA; DNA, Mitochondrial; Female; HLA-DR Antigens; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Leukocytes; Lipopolysaccharides; Male; Middle Aged; Myelodysplastic Syndromes; Young Adult

2017
Idarubicin-Intensified Hematopoietic Cell Transplantation Improves Relapse and Survival of High-Risk Acute Leukemia Patients with Minimal Residual Disease.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2019, Volume: 25, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Child; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia; Male; Middle Aged; Neoplasm, Residual; Recurrence; Retrospective Studies; Risk Factors; Survival Rate; Transplantation Conditioning

2019
FLAG vs FLAG-IDA: outcomes in relapsed/refractory acute leukemias.
    Cancer chemotherapy and pharmacology, 2019, Volume: 83, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Middle Aged; Pakistan; Progression-Free Survival; Recurrence; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Survival Rate; Vidarabine; Young Adult

2019
Acquired resistance of leukemic cells to AraC is associated with the upregulation of aldehyde dehydrogenase 1 family member A2.
    Experimental hematology, 2013, Volume: 41, Issue:7

    Topics: Aldehyde Dehydrogenase 1 Family; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Enzyme Induction; Gene Expression Regulation, Leukemic; Humans; Idarubicin; K562 Cells; Leukemia; Leukemia, Erythroblastic, Acute; Neoplasm Proteins; Prodrugs; Retinal Dehydrogenase; RNA Interference; RNA, Small Interfering; Transfection; Up-Regulation

2013
Sequential combination of decitabine and idarubicin synergistically enhances anti-leukemia effect followed by demethylating Wnt pathway inhibitor promoters and downregulating Wnt pathway nuclear target.
    Journal of translational medicine, 2014, Jun-12, Volume: 12

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Nucleus; Cell Proliferation; Decitabine; Down-Regulation; Drug Synergism; Humans; Idarubicin; In Situ Nick-End Labeling; Leukemia; Methylation; Mice; Mice, Inbred NOD; Mice, SCID; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; U937 Cells; Wnt Proteins

2014
Sequential development of different acute leukemia types in the same patient.
    Blood, 2014, Oct-16, Volume: 124, Issue:16

    Topics: Acute Disease; Antineoplastic Agents; Cytarabine; Humans; Idarubicin; Leukemia; Lymph Nodes; Male; Middle Aged; Neoplasm Recurrence, Local

2014
A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia.
    Acta pharmacologica Sinica, 2009, Volume: 30, Issue:10

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Aspergillus; Busulfan; China; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Idarubicin; Immunosuppressive Agents; Leukemia; Leukemia, Myeloid, Acute; Male; Methylprednisolone; Mucositis; Pneumonia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Premedication; Retrospective Studies; Risk Factors; Semustine; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation

2009
The cytotoxic effects of gemtuzumab ozogamicin (mylotarg) in combination with conventional antileukemic agents by isobologram analysis in vitro.
    Anticancer research, 2009, Volume: 29, Issue:11

    Topics: Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Gemtuzumab; HL-60 Cells; Humans; Idarubicin; Immunotoxins; Leukemia; Mercaptopurine; Methotrexate; Mitoxantrone; Sialic Acid Binding Ig-like Lectin 3; U937 Cells; Vincristine

2009
Development of idarubicin and doxorubicin solid lipid nanoparticles to overcome Pgp-mediated multiple drug resistance in leukemia.
    Journal of biomedical nanotechnology, 2009, Volume: 5, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Colonic Neoplasms; Doxorubicin; Drug Resistance, Multiple; Humans; Idarubicin; Leukemia; Lipids; Mice; Mice, Nude; Nanoparticles; Treatment Outcome

2009
Leukaemia cutis at the site of striae distensae: an isotopic response?
    Acta dermato-venereologica, 2010, Volume: 90, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Atrophy; Biopsy; Cytarabine; Female; Humans; Idarubicin; Leukemia; Middle Aged; Skin; Skin Diseases; Skin Neoplasms; Treatment Outcome

2010
[NT-pro-BNP in the evaluation of daunorubicin-indued cardiotoxicity in acute childhood leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2010, Volume: 31, Issue:9

    Topics: Anthracyclines; Cardiotoxicity; Daunorubicin; Humans; Idarubicin; Leukemia

2010
The in-vitro antiproliferative effect of PRI-2191 and imatinib applied in combined treatment with cisplatin, idarubicin, or docetaxel on human leukemia cells.
    Anti-cancer drugs, 2012, Volume: 23, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Cell Cycle Checkpoints; Cell Proliferation; Cisplatin; Dihydroxycholecalciferols; Docetaxel; G1 Phase Cell Cycle Checkpoints; HL-60 Cells; Humans; Idarubicin; Imatinib Mesylate; K562 Cells; Leukemia; Piperazines; Pyrimidines; Taxoids

2012
Oxidized phospholipid based pH sensitive micelles for delivery of anthracyclines to resistant leukemia cells in vitro.
    International journal of pharmaceutics, 2012, Jan-17, Volume: 422, Issue:1-2

    Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Doxorubicin; Drug Carriers; Drug Compounding; Drug Resistance, Neoplasm; Drug Stability; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Idarubicin; Kinetics; Leukemia; Mice; Micelles; Oxidation-Reduction; Particle Size; Phosphorylcholine; Solubility; Solvents; Technology, Pharmaceutical

2012
Amifostine differentially modulates DNA damage evoked by idarubicin in normal and leukemic cells.
    Leukemia research, 2002, Volume: 26, Issue:12

    Topics: Amifostine; Animals; Cell Line, Transformed; Cell Survival; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Drug Interactions; Humans; Idarubicin; Leukemia; Mice; Oncogene Proteins, Fusion; Protein-Tyrosine Kinases; Tumor Cells, Cultured

2002
Inactivation of deoxycytidine kinase and overexpression of P-glycoprotein in AraC and daunorubicin double resistant leukemic cell lines.
    Leukemia research, 2003, Volume: 27, Issue:5

    Topics: 2-Chloroadenosine; Alternative Splicing; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azacitidine; Biological Transport; Buthionine Sulfoximine; Calcium Channel Blockers; Cytarabine; Daunorubicin; Decitabine; Deoxyadenosines; Deoxycytidine Kinase; DNA Mutational Analysis; DNA, Neoplasm; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glutathione; Humans; Idarubicin; Leukemia; Methotrexate; Neoplasm Proteins; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Verapamil

2003
Activation of caspases-3/7 is dispensable for idarubicin-induced apoptotic DNA fragmentation in human leukemia cells.
    International journal of oncology, 2003, Volume: 22, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Caspases; DNA Fragmentation; Enzyme Activation; HL-60 Cells; Humans; Idarubicin; Jurkat Cells; Kinetics; Leukemia; Serine Proteinase Inhibitors; Tumor Cells, Cultured

2003
Fludarabine, cytosine arabinoside, granulocyte-colony stimulating factor with or without idarubicin in the treatment of high risk acute leukaemia or myelodysplastic syndromes.
    British journal of haematology, 2004, Volume: 127, Issue:2

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Myelodysplastic Syndromes; Vidarabine

2004
Antileukemia activity of the combination of an anthracycline with a histone deacetylase inhibitor.
    Blood, 2006, Aug-15, Volume: 108, Issue:4

    Topics: Acetylation; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Gene Expression Regulation, Leukemic; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; HL-60 Cells; Humans; Hydroxamic Acids; Idarubicin; Leukemia; Protein Processing, Post-Translational; RNA, Messenger; Valproic Acid; Vorinostat

2006
Divergent cytotoxic effects of PKC412 in combination with conventional antileukemic agents in FLT3 mutation-positive versus -negative leukemia cell lines.
    Leukemia, 2007, Volume: 21, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Line, Tumor; Cytarabine; Doxorubicin; Etoposide; fms-Like Tyrosine Kinase 3; Humans; Idarubicin; Leukemia; Methotrexate; Mitoxantrone; Mutation; Protein Kinase C; Staurosporine

2007
Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells.
    Leukemia & lymphoma, 2008, Volume: 49, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Cytarabine; Deoxycytidine; Drug Interactions; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Hydrazines; Idarubicin; Irinotecan; Leukemia; Lymphoma; Sulfonamides; Topotecan

2008
Therapeutic activity of 4-demethoxydauno-rubicin (idarubicin) in adult acute leukemia.
    Tumori, 1983, Dec-31, Volume: 69, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Drug Evaluation; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged; Time Factors

1983
Phase I trial of Idarubicin (4-demethoxydaunorubicin) in adult acute leukemia.
    Investigational new drugs, 1984, Volume: 2, Issue:4

    Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Female; Gastrointestinal Diseases; Humans; Idarubicin; Leukemia; Leukopenia; Male; Middle Aged

1984
Angiotensin converting enzyme inhibitors in bone marrow transplant recipients with depressed left ventricular function.
    Bone marrow transplantation, 1995, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Angiotensin-Converting Enzyme Inhibitors; Antibiotics, Antineoplastic; Antineoplastic Agents; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Daunorubicin; Doxorubicin; Echocardiography, Doppler, Color; Enalapril; Female; Gated Blood-Pool Imaging; Heart Failure; Humans; Idarubicin; Leukemia; Male; Middle Aged; Radiation Injuries; Radiotherapy; Ventricular Dysfunction, Left; Ventricular Function, Left

1995
Idarubicin-related side effects in recipients of T-cell-depleted allogeneic bone marrow transplants are schedule dependent.
    Seminars in oncology, 1993, Volume: 20, Issue:6 Suppl 8

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Heart; Humans; Idarubicin; Leukemia; Lymphoma, Non-Hodgkin; Male; Middle Aged; Mouth Mucosa; Premedication; Stomatitis; Survival Analysis

1993
Action mechanism of idarubicin (4-demethoxydaunorubicin) as compared with daunorubicin in leukemic cells.
    International journal of hematology, 1993, Volume: 57, Issue:2

    Topics: Daunorubicin; Humans; Idarubicin; Leukemia; Tumor Cells, Cultured

1993
The potential of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide to circumvent three multidrug-resistance phenotypes in vitro.
    Cancer chemotherapy and pharmacology, 1997, Volume: 39, Issue:5

    Topics: Acridines; Amsacrine; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Cell Line; Cell Survival; Daunorubicin; Drug Resistance, Multiple; HL-60 Cells; Humans; Idarubicin; Leukemia; Paclitaxel; Phenotype; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Verapamil

1997
Study of the apoptosis induced in vitro by antitumoral drugs on leukaemic cells.
    Leukemia research, 1997, Volume: 21, Issue:2

    Topics: Acute Disease; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cell Cycle; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Idarubicin; Kinetics; Leukemia; Mitoxantrone

1997
Effect of the multidrug inhibitor GG918 on drug sensitivity of human leukemic cells.
    Leukemia, 1997, Volume: 11, Issue:9

    Topics: Acridines; Acute Disease; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Membrane Permeability; Drug Resistance, Multiple; Gene Expression; Humans; Idarubicin; Isoquinolines; Leukemia; Mitoxantrone; RNA, Messenger; RNA, Neoplasm; Tetrahydroisoquinolines; Tumor Cells, Cultured; Verapamil

1997
Intracellular pharmacokinetics of anthracyclines in human leukemia cells: correlation of DNA-binding with apoptotic cell death.
    International journal of clinical pharmacology and therapeutics, 1998, Volume: 36, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; Cell Nucleus; Daunorubicin; DNA Damage; DNA, Neoplasm; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Idarubicin; Leukemia

1998
The ability of verapamil to restore intracellular accumulation of anthracyclines in multidrug resistant cells depends on the kinetics of their uptake.
    European journal of pharmacology, 1998, Feb-19, Volume: 343, Issue:2-3

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Daunorubicin; Doxorubicin; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Idarubicin; Leukemia; Tumor Cells, Cultured; Verapamil

1998
Early detection by ultrasound scan of severe post-chemotherapy gut complications in patients with acute leukemia.
    Haematologica, 1999, Volume: 84, Issue:3

    Topics: Acute Disease; Adult; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dilatation, Pathologic; Enterocolitis; Etoposide; Female; Gallbladder Diseases; Gastrointestinal Diseases; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Intubation, Gastrointestinal; Leukemia; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Ultrasonography

1999
Cellular uptake and antiproliferative effects of therapeutic concentrations of idarubicin or daunorubicin and their alcohol metabolites, with or without cyclosporin A, in MDR1+ human leukemic cells.
    Leukemia & lymphoma, 1999, Volume: 33, Issue:5-6

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Idarubicin; Immunosuppressive Agents; Leukemia; Tumor Cells, Cultured

1999
Altered drug sensitivity in response to idarubicin treatment in K562 human leukaemia cells.
    British journal of haematology, 1999, Volume: 106, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Blotting, Western; DNA Topoisomerases, Type II; Drug Resistance, Multiple; Humans; Idarubicin; K562 Cells; Leukemia

1999
Influence of serum protein binding on the uptake and retention of idarubicin by sensitive and multidrug resistant human leukemic cells.
    European journal of clinical pharmacology, 1999, Volume: 55, Issue:5

    Topics: Anti-Arrhythmia Agents; Blood Proteins; Cell Line; Drug Resistance, Multiple; Humans; Hypersensitivity; Idarubicin; Leukemia; Protein Binding; Time Factors; Tumor Cells, Cultured; Verapamil

1999
Contribution of the nucleoside transport system to doxorubicin transport in HL60 cells but not in mononuclear cells.
    Japanese journal of cancer research : Gann, 1999, Volume: 90, Issue:7

    Topics: Antibiotics, Antineoplastic; Biological Transport; Carrier Proteins; Daunorubicin; Doxorubicin; Drug Interactions; HL-60 Cells; Humans; Idarubicin; In Vitro Techniques; Leukemia; Leukocytes, Mononuclear; Membrane Proteins; Nucleoside Transport Proteins; Sodium

1999
Flow cytometry detection of caspase 3 activation in preapoptotic leukemic cells.
    Cytometry, 2000, Jun-01, Volume: 40, Issue:2

    Topics: Adult; Annexin A5; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Apoptosis; Biomarkers; Blotting, Western; Bone Marrow Cells; Camptothecin; Caspase 3; Caspase 7; Caspases; Daunorubicin; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Idarubicin; Leukemia; Peptide Hydrolases; Protein Binding; U937 Cells

2000
Combination chemotherapy of intermediate-dose cytarabine, idarubicin, plus etoposide and subsequent mobilized donor leukocyte infusion for relapsed acute leukemia after allogeneic bone marrow transplantation.
    Leukemia research, 2001, Volume: 25, Issue:4

    Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft vs Host Disease; Hematopoietic Stem Cell Mobilization; Humans; Idarubicin; Leukemia; Leukocyte Transfusion; Male; Recurrence; Survival Rate; Transplantation, Homologous

2001
Treatment of relapse after allogeneic bone marrow transplantation with reduced intensity conditioning (FLAG +/- Ida) and second allogeneic stem cell transplant.
    British journal of haematology, 2001, Volume: 115, Issue:3

    Topics: Acute Disease; Adult; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Filgrastim; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; Recurrence; Reoperation; Retrospective Studies; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Vidarabine

2001
Standard versus alternative myeloablative conditioning regimens in allogeneic hematopoietic stem cell transplantation for high-risk acute leukemia.
    Haematologica, 2002, Volume: 87, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Immunosuppressive Agents; Infant; Leukemia; Life Tables; Male; Methylprednisolone; Middle Aged; Premedication; Retrospective Studies; Risk; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation

2002
Comparison of idarubicin and daunorubicin regarding intracellular uptake, induction of apoptosis, and resistance.
    Cancer letters, 2002, Apr-25, Volume: 178, Issue:2

    Topics: Antibiotics, Antineoplastic; Apoptosis; Cell Survival; Daunorubicin; Drug Resistance; Drug Resistance, Neoplasm; Humans; Idarubicin; Leukemia; Tumor Cells, Cultured

2002
In vitro evaluation of the efficacy of idarubicin in human tumour cells from patients with low-grade non-Hodgkin's lymphoma.
    British journal of haematology, 2002, Volume: 117, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Cell Survival; Female; Humans; Idarubicin; Leukemia; Lymphoma, Non-Hodgkin; Male; Middle Aged; Tumor Cells, Cultured

2002
Formation and longevity of idarubicin-induced DNA topoisomerase II cleavable complexes in K562 human leukaemia cells.
    Biochemical pharmacology, 2002, May-15, Volume: 63, Issue:10

    Topics: Antibiotics, Antineoplastic; Catalytic Domain; Daunorubicin; DNA; DNA Topoisomerases, Type II; Enzyme Inhibitors; Fluorescent Antibody Technique; Humans; Idarubicin; K562 Cells; Leukemia; Topoisomerase II Inhibitors

2002
Oral manifestations of acute myelomonocytic leukemia: a case report and review of the classification of leukemias.
    Journal of periodontology, 2002, Volume: 73, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fatal Outcome; Gingival Hemorrhage; Gingival Overgrowth; Humans; Idarubicin; Leukemia; Leukemia, Myelomonocytic, Acute; Male; Middle Aged

2002
[Diagnostic image (92). A man with fever during chemotherapy. Invasive pulmonary mycosis].
    Nederlands tijdschrift voor geneeskunde, 2002, Jun-15, Volume: 146, Issue:24

    Topics: Amphotericin B; Antibiotics, Antineoplastic; Antifungal Agents; Antimetabolites, Antineoplastic; Cytarabine; Fever; Humans; Idarubicin; Leukemia; Lung; Lung Diseases, Fungal; Male; Middle Aged; Radiography

2002
[A pharmacokinetic study of idarubicin hydrochloride, a new anthracycline anti-tumor drug, in patients with acute leukemia. Idarubicin Study Group].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:6

    Topics: Acute Disease; Blast Crisis; Humans; Idarubicin; Infusions, Intravenous; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive

1992
Idarubicin in combination with intermediate-dose cytarabine in the treatment of refractory or relapsed acute leukemias.
    European journal of haematology, 1989, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1989
4-demethoxydaunorubicin (idarubicin) in combination with 1-beta-D-arabinofuranosylcytosine in the treatment of relapsed or refractory acute leukemia.
    Cancer research, 1989, Jan-15, Volume: 49, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged

1989
Idarubicin: a new presence in leukemias. Satellite symposium. Milan, August 1988. Proceedings.
    Seminars in oncology, 1989, Volume: 16, Issue:1 Suppl 2

    Topics: Animals; Humans; Idarubicin; Leukemia

1989
Phase I clinical trial of orally administered 4-demethoxydaunorubicin (idarubicin) with pharmacokinetic and in vitro drug sensitivity testing in children with refractory leukemia.
    Cancer research, 1988, Sep-15, Volume: 48, Issue:18

    Topics: Acute Disease; Adolescent; Child; Child, Preschool; Daunorubicin; Drug Evaluation; Female; Heart; Humans; Idarubicin; Leukemia; Liver; Male; Tumor Stem Cell Assay

1988
Oral idarubicin in adult acute leukemia: a preliminary experience.
    Tumori, 1986, Apr-30, Volume: 72, Issue:2

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Antibiotics, Antineoplastic; Daunorubicin; Female; Humans; Idarubicin; Leukemia; Leukocyte Count; Male; Middle Aged

1986
Oral idarubicin in combination with cytosine-arabinoside in previously untreated patients with acute non-lymphocytic leukemia.
    American journal of clinical oncology, 1986, Volume: 9, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged

1986
Plasma and human leukemic cell pharmacokinetics of oral and intravenous 4-demethoxydaunomycin.
    Clinical pharmacology and therapeutics, 1986, Volume: 40, Issue:6

    Topics: Administration, Oral; Daunorubicin; Humans; Idarubicin; Infusions, Intravenous; Kinetics; Leukemia

1986
Phase I and clinical pharmacological study of 4-demethoxydaunorubicin (idarubicin) in children with advanced cancer.
    Cancer research, 1987, Jun-01, Volume: 47, Issue:11

    Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Daunorubicin; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Idarubicin; Infant; Leukemia; Metabolic Clearance Rate; Neoplasms

1987
Idarubicin in sequential combination with cytosine arabinoside in the treatment of relapsed and refractory patients with acute non-lymphoblastic leukemia.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged

1987
Idarubicin in combination with etoposide and cytarabine in adult untreated acute non lymphoblastic leukemia.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:11

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged

1987
Phase I and II clinical and pharmacological study of 4-demethoxydaunorubicin (idarubicin) in adult patients with acute leukemia.
    Cancer research, 1985, Volume: 45, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Daunorubicin; Drug Evaluation; Female; Humans; Idarubicin; Kinetics; Leukemia; Male; Middle Aged

1985
4-Demethoxydaunorubicin (Idarubicin) in refractory or relapsed acute leukemias. A pilot study.
    Cancer, 1985, Apr-01, Volume: 55, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Daunorubicin; Drug Evaluation; Drug Resistance; Female; Humans; Idarubicin; Leukemia; Leukemia, Lymphoid; Male; Middle Aged; Pilot Projects

1985
Intravenous and oral demethoxydaunorubicin (NSC 256-439) in the treatment of acute leukemia and lymphoma: a pilot study.
    Blut, 1985, Volume: 50, Issue:6

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Antineoplastic Agents; Daunorubicin; Female; Humans; Idarubicin; Injections, Intravenous; Leukemia; Lymphoma; Male; Middle Aged; Multiple Myeloma; Pilot Projects

1985
Idarubicin alone or in combination with cytarabine and etoposide (3 + 3 + 5 protocol) in acute non-lymphoblastic leukaemia.
    Leukemia research, 1985, Volume: 9, Issue:5

    Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged

1985
Phase-I trial of 4-demethoxydaunorubicin in acute leukaemias.
    Investigational new drugs, 1985, Volume: 3, Issue:4

    Topics: Acute Disease; Adult; Antineoplastic Agents; Bone Marrow; Daunorubicin; Drug Evaluation; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged

1985
Preliminary results in secondary acute non-lymphocytic leukemia (ANLL) treated with Idarubicin.
    Nouvelle revue francaise d'hematologie, 1985, Volume: 27, Issue:6

    Topics: Adult; Aged; Daunorubicin; Female; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local

1985