idarubicin has been researched along with Acute Lymphoid Leukemia in 99 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (3.03) | 18.7374 |
| 1990's | 44 (44.44) | 18.2507 |
| 2000's | 38 (38.38) | 29.6817 |
| 2010's | 13 (13.13) | 24.3611 |
| 2020's | 1 (1.01) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, D; Wang, ZD; Zhang, CH; Zhang, Q | 1 |
| Fang, J; Hong, M; Li, WM; Lu, X; Shi, W; Wang, HF; Wang, YD; Wu, QL; Xia, LH; You, Y; Zhang, C; Zhang, R; Zheng, P; Zhong, ZD | 1 |
| Aymerich, M; Bataller, A; Camós, M; Colomer, D; Díaz-Beyá, M; Esteve, J; Garrote, M; López-Guerra, M; Oliver-Caldés, A; Vega-García, N | 1 |
| Abdalla, K; Abrar, MB; AlAzmi, AA; Elimam, N; Jastaniah, W; Mustafa, O | 1 |
| Devidas, M; Gaynon, PS; Ji, L; Sather, H; Seibel, NL; Steinherz, PG; Xu, X | 1 |
| Bourquin, JP; Creutzig, U; Dworzak, MN; Fleischhack, G; Graf, N; Klingebiel, T; Kremens, B; Lehrnbecher, T; Reinhardt, D; Ritter, J; Sander, A; Schrauder, A; Starý, J; von Neuhoff, C; von Stackelberg, A; Zimmermann, M | 1 |
| Arsikin, K; Bogdanovic, A; Bosnjak, M; Bumbasirevic, V; Harhaji-Trajkovic, L; Kravic-Stevovic, T; Martinovic, T; Mircic, A; Perovic, V; Ristic, B; Suzin-Zivkovic, V; Trajkovic, V | 1 |
| Fang, J; Hong, M; Hu, Y; Li, W; Nie, D; Wang, H; Wu, Q; Xia, L; You, Y; Zhang, R; Zhong, Z | 1 |
| Laskowska, J; Lewandowska-Bieniek, J; Styczyński, J; Szczepanek, J; Tretyn, A | 1 |
| Ahn, HS; Im, HJ; Kang, HJ; Kim, H; Koh, KN; Koo, HH; Lee, JW; Lim, YT; Park, BK; Park, HJ; Park, JE; Park, KD; Seo, JJ; Shin, HY; Sung, KW; Yoo, KH | 1 |
| Borowitz, MJ; Camitta, BM; Carroll, WL; Devidas, M; Gaynon, PS; Hunger, SP; Linda, SB; Raetz, EA; Winick, NJ | 1 |
| Hong, M; Li, JY; Qian, SX; Qiu, HX; Wu, HX; Xu, W; Zhang, R | 1 |
| Ahn, HS; Kang, HJ; Kim, EK; Park, JA; Shin, HY; Yoon, JH | 1 |
| Darzynkiewicz, Z; Halicka, HD; Jayabose, S; Kajstura, M; Levendoglu-Tugal, O; Ozkaynak, MF; Sandoval, C; Seiter, K; Traganos, F | 1 |
| Bargetzi, M; Dudler, C; Gratwohl, A; Passweg, JR; Tichelli, A; Wernli, M | 1 |
| Chen, ZC; Li, L; Li, QB; Xia, LH; You, Y; Zou, P | 1 |
| Dada, R; Galm, O; Gassler, N; Jost, E; Osieka, R; Wilop, S | 1 |
| Aytac, S; Balci, YI; Cetin, M; Gumruk, F; Gurgey, A; Kuskonmaz, B; Tavil, B; Tuncer, M; Uckan, D; Unal, S; Yetgin, S | 1 |
| Ancliff, P; Darbyshire, P; Goulden, N; Green, N; Hancock, J; Leighton, C; Love, S; Masurekar, A; Moorman, AV; Morgan, M; Parker, C; Révész, T; Saha, V; Sutton, R; Waters, R | 1 |
| Schrappe, M | 1 |
| Békàssy, AN; Glomstein, A; Lähteenmäki, PM; Möttönen, M; Parto, K; Riikonen, P; Saarinen-Pihkala, UM | 1 |
| Balcerska, A; Balwierz, W; Chybicka, A; Debski, R; Kowalczyk, J; Kurylak, A; Matysiak, M; Rokicka-Milewska, R; Sońta-Jakimczyk, D; Styczyński, J; Wachowiak, J; Wysocki, M | 1 |
| Batár, P; Kiss, A; Rák, K; Rejtó, L; Reményi, G; Telek, B; Udvardy, M | 1 |
| Handa, H; Isozumi, K; Komatsumoto, S; Motohashi, S; Nara, M | 1 |
| Arcese, W; Aricò, M; Barisone, E; Basso, G; Biondi, A; Casale, F; Comis, M; Conter, V; Del Giudice, I; Dini, G; Giona, F; Ladogana, S; Lippi, A; Locatelli, F; Mandelli, F; Masera, G; Messina, C; Micalizzi, C; Micozzi, A; Moleti, ML; Mura, R; Pinta, MF; Rondelli, R; Santoro, N; Testi, AM; Valsecchi, MG | 1 |
| Aliff, TB; Frankel, SR; Jurcic, JG; Kalaycio, ME; Maslak, PG; Roma, TE; Scheinberg, DA; Tallman, MS; Weiss, MA | 1 |
| Debatin, KM; Eckhoff, S; Meyer, LH; Mohr, A; Stahnke, K | 1 |
| Ault, K; Case, D; Damon, LE; Johnston, LJ; Linker, CA; Ries, CA; Rugo, HS | 1 |
| Dutcher, JP; Karbasian-Esfahani, M; Novik, Y; Paietta, E; Wiernik, PH | 1 |
| Avramis, V; Douglas, JG; Felgenhauer, J; Geyer, JR; Hawkins, DS; Holcenberg, J; Loken, MR; Meshinchi, S; Park, JR; Thomson, B | 1 |
| Boiron, JM; Boulat, O; Espinouse, D; Fiere, D; Garban, F; Gardin, C; Huguet, F; Lhéritier, V; Reman, O; Sutton, L; Thomas, X; Turlure, P | 1 |
| Chi, HS; Choi, SJ; Jang, S; Kim, S; Kim, WK; Lee, JH; Lee, JS; Lee, KH; Lee, YS; Park, CJ; Ryu, SG; Seol, M | 1 |
| Ahmed, P; Anwar, M; Hashmi, KU; Hussain, I; Iqbal, H; Khan, B; Mahmood, A; Malik, HS; Raza, S | 1 |
| Carluccio, P; Ciuffreda, L; Liso, A; Liso, V; Mestice, A; Pastore, D; Pietrantuono, G; Rizzi, R; Specchia, G | 1 |
| Disel, U; Paydas, S; Yavuz, S | 1 |
| Hayashi, Y; Kanazawa, T; Morikawa, A; Ogawa, C; Taketani, T; Taki, T | 1 |
| Escherich, G; Hassenpflug, WA; Horstmann, MA; Janka, G; Kabisch, H; zur Stadt, U | 1 |
| Du, X; Ke, XY; Liu, Y; Lü, JQ; Lu, ZS; Ma, J; Shen, ZX; Xu, XH; Zeng, XY; Zhan, ZM; Zhang, XH; Zhao, YM | 1 |
| Baratè, C; Cafro, AM; Camaggi, CM; Intropido, L; Marbello, L; Montillo, M; Morra, E; Nichelatti, M; Strocchi, E; Tedeschi, A; Tresoldi, E | 1 |
| Du, X; Ke, XY; Liu, Y; Lu, ZS; Lv, JQ; Ma, J; Shen, ZX; Xu, XH; Zeng, XY; Zhan, ZM; Zhang, XH; Zhao, YM | 1 |
| Chen, S; Fu, Z; Han, Y; Hu, X; Jin, Z; Ma, X; Miao, M; Qiu, H; Sun, A; Tang, X; Wu, D | 1 |
| Bárdi, E; Bobok, I; Kappelmayer, J; Kiss, C; V Oláh, A | 1 |
| Chen, J; Gu, LJ; Li, J; Pan, C; Tang, JY; Xue, HL; Ye, H; Zhao, HJ | 1 |
| Bassan, R; Battista, R; Borleri, G; Buelli, M; D'Emilio, A; Lambertenghi-Deliliers, G; Pogliani, E; Rambaldi, A; Rossi, G; Viero, P | 1 |
| Hählen, K; Hartmann, R; Henze, G; Huismans, DR; Kaspers, GJ; Klumper, E; Loonen, AH; Pieters, R; van Wering, ER; Veerman, AJ | 1 |
| Archimbaud, E; Muus, P; Willemze, R | 1 |
| den Boer, ML; Huismans, DR; Klumper, E; Loonen, AH; Pieters, R; Veerman, AJ | 1 |
| D'Onofrio, G; Di Mario, A; Etuk, B; Leone, G; Salutari, P; Sica, S | 1 |
| Cianfriglia, M; Eisterer, W; Gotwald, M; Hilbe, W; Hofmann, J; Ludescher, C; Thaler, J; Zabernigg, A | 1 |
| Welborn, JL | 1 |
| Amadori, S; Annino, L; Arcese, W; Camera, A; Di Montezemolo, LC; Giona, F; Ladogana, S; Liso, V; Meloni, G; Testi, AM | 1 |
| Kimura, K; Masaoka, T; Ogawa, M; Yamada, K | 2 |
| Bassan, R; Battista, R; Corneo, G; D'Emilio, A; Lambertenghi-Deliliers, G; Neonato, MG; Pogliani, E; Rambaldi, A; Rossi, G; Viero, P | 1 |
| Berman, E | 1 |
| Berman, E; Gaynor, J; Gee, T; Kempin, S; Kritz, A; Little, C; Scheinberg, D; Sogoloff, H; Telford, P; Weiss, M | 1 |
| Annino, L; Mandelli, F; Rotoli, B | 1 |
| Barbui, T; Bassan, R; Di Bona, E; Fabris, P; Lambertenghi-Deliliers, G; Lerede, T; Pogliani, E; Porcellini, A; Rambaldi, A; Rossi, G | 1 |
| Barbui, T; Bassan, R; Lerede, T; Rambaldi, A | 1 |
| Barbui, T; Bassan, R; Buelli, M; D'Emilio, A; Di Bona, E; Lerede, T; Pogliani, E; Rambaldi, A; Rodeghiero, F; Rossi, G; Viero, P | 1 |
| Ames, MM; Bleyer, WA; Feig, SA; Gerber, M; Harris, RE; Leonard, M; Pendergrass, TW; Reid, JM; Sather, HN; Steinherz, L; Trigg, M; Warkentin, P | 1 |
| Abenhardt, W; Diem, H; Gieseler, F; Gullis, E; Kolb, HJ; Langenmayer, I; Nüssler, V; Pelka-Fleischer, R; Schmitt, R; Wilmanns, W; Wohlrab, A; Zwierzina, H | 1 |
| Archimbaud, E; Berneman, Z; Dardenne, M; Dohner, H; Jaksic, B; Jehn, U; Labar, B; Louwagie, EA; Muus, P; Stryckmans, P; Suciu, S; Tjean, M; Wijermans, P; Willemze, R; Zittoun, R | 1 |
| Amadori, S; Annino, L; Arcese, W; Camera, A; Fioritoni, G; Giona, F; Ladogana, S; Leoni, P; Liso, V; Mandelli, F; Meloni, G; Moleti, ML; Resegotti, L; Rondelli, R; Tabilio, A; Testi, AM | 1 |
| Bührer, C; Hartmann, R; Henze, G; Klumper, E; Neuendank, A; Veerman, AJ; Winterhalter, B | 1 |
| Barbui, T; Bassan, R; Buelli, M; Corneo, G; Di Bona, E; Izzi, T; Lerede, T; Pogliani, E; Rambaldi, A; Rodeghiero, F; Rossi, G; Viero, P | 1 |
| Avramis, VI; Dinndorf, PA; Kelleher, JF; Krailo, MD; Liu-Mares, W; Mosher, RB; Reaman, GH; Sato, JK; Seibel, NL; Wiersma, S | 1 |
| Amadori, S; Arcese, W; Ceci, A; Comis, M; Giona, F; Madon, E; Mandelli, F; Meloni, G; Moleti, ML; Pession, A; Pillon, M; Rondelli, R; Testi, AM | 1 |
| Barbui, T; Bassan, R; Borleri, G; Chiodini, B; Lerede, T; Rambaldi, A; Torri, V | 1 |
| Apel, D; Maj, S; Mariańska, B; Seferyńska, I | 1 |
| Drullinsky, P; Golde, DW; Maslak, P; Scheinberg, D; Weiss, MA | 1 |
| Deane, M; Foroni, L; Galactowicz, G; Hoffbrand, AV; Koh, M; Lawler, M; Prentice, HG; Secker-Walker, L | 1 |
| Annino, L; Arcese, W; Giona, F; Mandelli, F; Meloni, G; Moleti, ML; Rondelli, R; Testi, AM | 1 |
| Camera, A; Catalano, L; Picardi, M; Rotoli, B; Selleri, C | 1 |
| Barbui, T; Bassan, R; Corneo, G; D'Emilio, A; Di Bona, E; Izzi, T; Lambertenghi-Deliliers, G; Lerede, T; Oriani, A; Pogliani, E; Rambaldi, A; Rossi, G | 1 |
| Ağaoğlu, L; Anak, S; Erdem, S; Gedikoğlu, G; Hacibektaşoğlu, A; Karakaş, Z | 1 |
| Barbui, T; Bassan, R; Casula, P; Corneo, G; Coser, P; Fabris, P; Izzi, T; Lambertenghi-Deliliers, G; Lerede, T; Morandi, S; Pogliani, E; Rossi, G; Vespignani, M | 1 |
| Mandelli, F; Montefusco, E | 1 |
| Belasco, JB; Bunin, NJ; Lange, BJ; Leahey, AM; Meek, R; Scher, C | 1 |
| de Witte, T; Preijers, F; Schaap, N; Schattenberg, A; van der Maazen, R | 1 |
| Huismans, DR; Pieters, R; Schuurhuis, GJ; Styczynski, J; Veerman, AJ; Wysocki, M | 1 |
| Balduzzi, A; Biagi, E; De Lorenzo, P; Rovelli, A; Tagliabue, A; Uderzo, C | 1 |
| Ahmed, T; Feldman, EJ; Kancherla, R; Liu, D; Papageorgio, C; Pozzuoli, M; Seiter, K; Sreekantaiah, C; Weisberger, J; Weiss, M | 1 |
| Barbui, T; Bassan, R; Borleri, G; Broccia, G; Casula, P; Corneo, G; Cortelezzi, A; Coser, P; Fabris, P; Izzi, T; Lambertenghi-Deliliers, G; Lerede, T; Morandi, S; Pogliani, E; Rambaldi, A; Rossi, G; Spedini, P; Vespignani, M | 1 |
| Craddock, C; Garg, M; Lawler, M; Pawson, R; Potter, MN; Prentice, HG; Rassam, S; Rezvani, K; Theocharous, P; Yin, JA | 1 |
| Bruggers, CS; Carroll, WL; Liu, T; Moos, PJ; Perkins, SL; Raetz, E; Smith, F | 1 |
| Döhner, H; Gabler, A; Haas, R; Hartmann, F; Hensel, M; Ho, AD; Jung, W; Schlenk, RF; Trümper, L; Weber-Nordt, R | 1 |
| Amadori, S; Giona, F; Iori, AP; Mandelli, F; Meloni, G; Miniero, R; Moleti, ML; Pigna, M; Testi, AM | 1 |
| Di Mario, A; Etuk, B; Leone, G; Pagano, L; Salutari, P; Sica, S | 1 |
| Cersosimo, RJ | 1 |
| Ames, MM; Kuffel, MJ; Reid, JM | 1 |
| Berman, E; McBride, M | 1 |
| Baum, E; Feig, SA; Harris, RE; Holcenberg, JS; Kaizer, H; Krailo, MD; Pendergrass, TW; Saunders, EF; Steinherz, L; Warkentin, PL | 1 |
| Berman, E; Bertino, J; Clarkson, B; Gee, T; Kempin, S; Weiss, M | 1 |
| Annino, L; Arcese, W; Carotenuto, M; Giona, F; Iori, AP; Madon, E; Meloni, G; Resegotti, L; Testi, AM; Vegna, ML | 1 |
| Amadori, S; Carella, AM; Carotenuto, M; Colella, R; Giona, F; Grotto, P; Leoni, P; Meloni, G; Resegotti, L; Testi, AM | 1 |
| Carella, AM; D'Amico, T; Damasio, E; Gaozza, E; Giordano, D; Nati, S; Piatti, G; Pungolino, E; Spriano, M | 1 |
| Annino, L; Avvisati, G; Carella, AM; Caronia, F; Carotenuto, M; Giona, F; Mandelli, F; Meloni, G; Petti, MC; Testi, AM | 1 |
| Mandelli, F; Petti, MC | 1 |
9 review(s) available for idarubicin and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
[Experience with fludarabine treatment and review of the literature].
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Immunophenotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; Remission Induction; Treatment Outcome; Vidarabine | 2002 |
A review of idarubicin in acute leukemia.
Topics: Adult; Aged; Child; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Daunorubicin; Europe; Humans; Idarubicin; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Randomized Controlled Trials as Topic; Treatment Outcome; United States | 1993 |
The role of anthracyclines in adult acute lymphoblastic leukaemia.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Disease-Free Survival; Doxorubicin; Humans; Idarubicin; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Randomized Controlled Trials as Topic; Translocation, Genetic | 1996 |
Role of anthracyclines in the treatment of adult acute lymphoblastic leukemia.
Topics: Adult; Antibiotics, Antineoplastic; Clinical Trials as Topic; Daunorubicin; Doxorubicin; Humans; Idarubicin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction | 1996 |
[Treatment of acute and chronic leukemias].
Topics: Acute Disease; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosome Aberrations; Combined Modality Therapy; Daunorubicin; Humans; Idarubicin; Karyotyping; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Randomized Controlled Trials as Topic; Transplantation, Autologous; Transplantation, Homologous | 1999 |
Secondary acute myelogenous leukemia and myelodysplasia without abnormalities of chromosome 11q23 following treatment of acute leukemia with topoisomerase II-based chemotherapy.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, Human, Pair 11; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cytarabine; Disease Progression; Disease-Free Survival; Enzyme Inhibitors; Etoposide; Female; Humans; Idarubicin; Incidence; Karyotyping; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Neoplasm Proteins; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Topoisomerase II Inhibitors; Treatment Outcome; Tretinoin | 2001 |
Aggressive chemotherapy for acute leukemia relapsed after bone marrow transplantation: a second chance?
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chemotherapy, Adjuvant; Cytarabine; Daunorubicin; Humans; Idarubicin; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Time Factors; Vincristine | 1992 |
Idarubicin: an anthracycline antineoplastic agent.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Breast Neoplasms; Cytarabine; Drug Labeling; Humans; Idarubicin; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1992 |
Intensive therapy for adult acute lymphoblastic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Humans; Idarubicin; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Vincristine | 1991 |
45 trial(s) available for idarubicin and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Randomized trial comparing liposomal daunorubicin with idarubicin as induction for pediatric acute myeloid leukemia: results from Study AML-BFM 2004.
Topics: Adolescent; Antibiotics, Antineoplastic; Bone Marrow; Child; Child, Preschool; Daunorubicin; Dose-Response Relationship, Drug; Female; Heart Diseases; Humans; Idarubicin; Leukemia, Myeloid, Acute; Liposomes; Male; Multivariate Analysis; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proportional Hazards Models; Risk Factors; Treatment Outcome | 2013 |
Outcome of Reinduction Chemotherapy with a Modified Dose of Idarubicin for Children with Marrow-Relapsed Acute Lymphoblastic Leukemia: Results of the Childhood Acute Lymphoblastic Leukemia (CALL)-0603 Study.
Topics: Adolescent; Antibiotics, Antineoplastic; Asparaginase; Bone Marrow; Child; Child, Preschool; Disease-Free Survival; Female; Humans; Idarubicin; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Recurrence; Remission Induction; Survival Rate; Treatment Outcome; Vincristine; Young Adult | 2017 |
Reinduction platform for children with first marrow relapse of acute lymphoblastic Leukemia: A Children's Oncology Group Study[corrected].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Central Nervous System Neoplasms; Child; Child, Preschool; Cytarabine; Dexamethasone; Doxorubicin; Female; Flow Cytometry; Humans; Idarubicin; Infant; Leukemia, T-Cell; Leukemic Infiltration; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction | 2008 |
[IDA-FLAG regimen in treatment of patients with refractory or relapsed acute leukemia].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine | 2009 |
DV-ICE, intensive induction and early transplantation for adult patients with acute lymphoblastic leukemia: a phase II study.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Dexamethasone; Disease-Free Survival; Early Termination of Clinical Trials; Etoposide; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Hydrocortisone; Idarubicin; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Treatment Failure; Vincristine; Young Adult | 2009 |
Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial.
Topics: Adolescent; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Etoposide; Female; Humans; Idarubicin; Infant; Kaplan-Meier Estimate; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Risk Assessment; Treatment Outcome; United Kingdom; Vidarabine; Vincristine | 2010 |
RALLE pilot: response-guided therapy for marrow relapse in acute lymphoblastic leukemia in children.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Bone Marrow; Child; Child, Preschool; Dexamethasone; Disease-Free Survival; Female; Humans; Idarubicin; Infant; Male; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Stem Cell Transplantation; Survival Rate; Transplantation, Homologous; Vincristine | 2012 |
A single high dose of idarubicin combined with high-dose ARA-C for treatment of first relapse in childhood 'high-risk' acute lymphoblastic leukaemia: a study of the AIEOP group.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Survival Rate | 2002 |
A single, high dose of idarubicin combined with cytarabine as induction therapy for adult patients with recurrent or refractory acute lymphoblastic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cognition; Conjunctivitis; Cytarabine; Dose-Response Relationship, Drug; Female; Fever; Heart; Hematemesis; Humans; Idarubicin; Male; Middle Aged; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Analysis; Treatment Outcome | 2002 |
Apoptosis induction in peripheral leukemia cells by remission induction treatment in vivo: selective depletion and apoptosis in a CD34+ subpopulation of leukemia cells.
Topics: Adult; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Child; Cytarabine; Etoposide; fas Receptor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytes, Mononuclear; Lymphocyte Depletion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Treatment Outcome | 2003 |
Treatment of acute leukemia with idarubicin, etoposide and cytarabine (IDEA). A randomized study of etoposide schedule.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Humans; Idarubicin; Middle Aged; Mouth Mucosa; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 2004 |
Idarubicin and standard-dose cytosine arabinoside in adults with recurrent and refractory acute lymphocytic leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Idarubicin; Infusions, Intravenous; Injections, Intravenous; Male; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Rate; Thrombocytopenia | 2004 |
Toxicity and efficacy of intensive chemotherapy for children with acute lymphoblastic leukemia (ALL) after first bone marrow or extramedullary relapse.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bacteremia; Bone Marrow Neoplasms; Child; Child, Preschool; Cytarabine; Dexamethasone; Etoposide; Female; Flow Cytometry; Humans; Idarubicin; Ifosfamide; Infant; Infusions, Intravenous; Leucovorin; Male; Mesna; Methotrexate; Mouth Mucosa; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Stomatitis; Thioguanine; Treatment Outcome; Vincristine | 2004 |
Efficacy of granulocyte and granulocyte-macrophage colony-stimulating factors in the induction treatment of adult acute lymphoblastic leukemia: a multicenter randomized study.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Daunorubicin; Disease-Free Survival; Drug Utilization; Female; Fever; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hospitalization; Humans; Idarubicin; Infection Control; Infections; Leukocyte Count; Male; Middle Aged; Neutropenia; Neutrophils; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Remission Induction; Salvage Therapy; Time Factors; Treatment Outcome; Vincristine | 2004 |
[Multi-institutional randomized controlled clinical trial on China made 4-demethoxydaunokrubicin (IDA) in the treatment of acute leukemia].
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; China; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Single-Blind Method | 2005 |
High-dose idarubicin in combination with Ara-C in patients with relapsed or refractory acute lymphoblastic leukemia: a pharmacokinetic and clinical study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Survival Analysis | 2007 |
[Multicenter randomized control trial on safety of domestic idarubicin for acute leukemia].
Topics: Adolescent; Adult; Aged; Agranulocytosis; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cyclophosphamide; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mucositis; Nausea; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Treatment Outcome; Vincristine | 2006 |
Clinical outcome of children with newly diagnosed acute lymphoblastic leukemia treated in a single center in Shanghai, China.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Central Nervous System Neoplasms; Child; Child, Preschool; China; Daunorubicin; Female; Health Care Costs; Humans; Idarubicin; Infant; Kaplan-Meier Estimate; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Remission Induction; Risk Assessment; Treatment Outcome; Vincristine | 2008 |
Intensive therapy for adult acute lymphoblastic leukemia: preliminary results of the idarubicin/vincristine/L-asparaginase/prednisolone regimen.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Combined Modality Therapy; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Immunophenotyping; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recombinant Proteins; Remission Induction; Vincristine | 1993 |
[A late phase II study of idarubicin hydrochloride in adult patients with acute lymphocytic leukemia. Idarubicin Study Group].
Topics: Adolescent; Adult; Aged; Electrocardiography; Female; Humans; Idarubicin; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Vincristine | 1993 |
[Early phase II study of Idarubicin, a new anthracycline anticancer drug, in acute leukemia. Idarubicin Study Group].
Topics: Adult; Aged; Alopecia; Drug Administration Schedule; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Vomiting | 1993 |
Severe toxicity limits intensification of induction therapy for acute lymphoblastic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Idarubicin; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Survival Analysis; Vincristine | 1993 |
The GIMEMA ALL 0183 trial: analysis of 10-year follow-up. GIMEMA Cooperative Group, Italy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Follow-Up Studies; Humans; Idarubicin; Male; Methotrexate; Middle Aged; Multivariate Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Survival Analysis; Survival Rate | 1996 |
Age-adapted moderate-dose induction and flexible outpatient postremission therapy for elderly patients with acute lymphoblastic leukemia.
Topics: Aged; Aging; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Male; Middle Aged; Outpatients; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Vincristine | 1996 |
Comparison of idarubicin to daunomycin in a randomized multidrug treatment of childhood acute lymphoblastic leukemia at first bone marrow relapse: a report from the Children's Cancer Group.
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Child, Preschool; Daunorubicin; Disease-Free Survival; Humans; Idarubicin; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Recurrence | 1996 |
A randomized phase II study on the effects of 5-Aza-2'-deoxycytidine combined with either amsacrine or idarubicin in patients with relapsed acute leukemia: an EORTC Leukemia Cooperative Group phase II study (06893).
Topics: Adolescent; Adult; Aged; Amsacrine; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Decitabine; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Survival Rate; Time Factors | 1997 |
Treatment of adults with acute lymphoblastic leukaemia in first bone marrow relapse: results of the ALL R-87 protocol.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Female; Humans; Idarubicin; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Recurrence; Survival Analysis; Survival Rate; Treatment Outcome | 1997 |
Acute toxicity and effectiveness of idarubicin in childhood acute lymphoblastic leukemia.
Topics: Adolescent; Child; Child, Preschool; Female; Hematologic Diseases; Humans; Idarubicin; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction | 1997 |
Granulocyte colony-stimulating factor (G-CSF, filgrastim) after or during an intensive remission induction therapy for adult acute lymphoblastic leukaemia: effects, role of patient pretreatment characteristics, and costs.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cost-Benefit Analysis; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Male; Middle Aged; Patient Selection; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prospective Studies; Recombinant Proteins; Remission Induction; Treatment Outcome; Vincristine | 1997 |
Phase I/II study of idarubicin given with continuous infusion fludarabine followed by continuous infusion cytarabine in children with acute leukemia: a report from the Children's Cancer Group.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Idarubicin; Infant; Infusions, Intravenous; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine | 1997 |
ALL R-87 protocol in the treatment of children with acute lymphoblastic leukaemia in early bone marrow relapse.
Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Infant; Leukocyte Count; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Recurrence; Risk Factors; Survival Analysis; Survival Rate; Treatment Outcome | 1997 |
[Preliminary treatment results of relapsed or refractory acute leukemia using two and three drug regimens].
Topics: Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Idarubicin; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction | 1998 |
A phase I trial of a single high dose of idarubicin combined with high-dose cytarabine as induction therapy in relapsed or refractory adult patients with acute lymphoblastic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Idarubicin; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1998 |
Management of advanced acute lymphoblastic leukemia in children and adults: results of the ALL R-87 protocol. AIEOP and GIMEMA Cooperative Groups.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Infant; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Remission Induction; Survival Rate; Treatment Outcome | 1998 |
Induction-consolidation with an idarubicin-containing regimen, unpurged marrow autograft, and post-graft chemotherapy in adult acute lymphoblastic leukaemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Disease-Free Survival; Female; Humans; Idarubicin; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Risk Factors; Transplantation, Homologous; Treatment Outcome; Vincristine | 1999 |
Fractionated cyclophosphamide added to the IVAP regimen (idarubicin-vincristine-L-asparaginase-prednisone) could lower the risk of primary refractory disease in T-lineage but not B-lineage acute lymphoblastic leukemia: first results from a phase II clinic
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Burkitt Lymphoma; Cyclophosphamide; Female; Humans; Idarubicin; Leukemia-Lymphoma, Adult T-Cell; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Vincristine | 1999 |
Novel multiagent chemotherapy for bone marrow relapse of pediatric acute lymphoblastic leukemia.
Topics: Adolescent; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Bone Marrow Transplantation; Central Nervous System Neoplasms; Child; Child, Preschool; Cytarabine; Dexamethasone; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Idarubicin; Infant; Injections, Spinal; Male; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Vincristine | 2000 |
Risk-oriented postremission strategies in adult acute lymphoblastic leukemia: prospective confirmation of anthracycline activity in standard-risk class and role of hematopoietic stem cell transplants in high-risk groups.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Male; Melphalan; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors; Transplantation, Homologous; Whole-Body Irradiation | 2001 |
Less intense conditioning with fludarabine, cyclophosphamide, idarubicin and etoposide (FCIE) followed by allogeneic unselected peripheral blood stem cell transplantation in elderly patients with leukemia.
Topics: Adult; Aged; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Cyclosporine; Etoposide; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Immunosuppressive Agents; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Chronic-Phase; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Vidarabine | 2002 |
Determination of the maximum tolerated dose of idarubicin when used in a combination chemotherapy program of reinduction of childhood ALL at first marrow relapse and a preliminary assessment of toxicity compared to that of daunorubicin: a report from the
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Child; Child, Preschool; Daunorubicin; Drug Administration Schedule; Female; Hematopoiesis; Humans; Idarubicin; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Vincristine | 1992 |
Intensive therapy for adult acute lymphoblastic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Humans; Idarubicin; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Vincristine | 1991 |
Idarubicin plus ARA-C followed by allogeneic or autologous bone marrow transplantation in advanced acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Humans; Idarubicin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Remission Induction; Transplantation, Autologous; Transplantation, Homologous | 1991 |
Idarubicin and high-dose cytarabine in the treatment of refractory and relapsed acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Humans; Idarubicin; Infant; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 1990 |
Idarubicin in acute leukaemia. GIMEMA Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Multicenter Studies as Topic; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1989 |
Idarubicin in acute leukemias: experience of the Italian Cooperative Group GIMEMA.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Random Allocation; Remission Induction | 1989 |
46 other study(ies) available for idarubicin and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Efficacy and safety of induction chemotherapy with daunorubicin or idarubicin in the treatment of an adult with acute lymphoblastic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2022 |
Idarubicin-intensified haploidentical HSCT with GvHD prophylaxis of ATG and basiliximab provides comparable results to sibling donors in high-risk acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antilymphocyte Serum; Basiliximab; Child; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Fusion Proteins; Siblings; Tissue Donors; Transplantation Conditioning; Young Adult | 2017 |
Early T-cell precursor lymphoblastic leukaemia: response to FLAG-IDA and high-dose cytarabine with sorafenib after initial refractoriness.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sorafenib; Treatment Outcome; Vidarabine | 2019 |
FLAG/FLAG-IDA regimen for children with relapsed/refractory acute leukemia in the era of targeted novel therapies.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Retrospective Studies; Vidarabine | 2019 |
Treatment of higher risk acute lymphoblastic leukemia in young people (CCG-1961), long-term follow-up: a report from the Children's Oncology Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Doxorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Young Adult | 2019 |
Idarubicin induces mTOR-dependent cytotoxic autophagy in leukemic cells.
Topics: Adult; Antibiotics, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Proliferation; Humans; Idarubicin; Immunoenzyme Techniques; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphocytes; Membrane Potential, Mitochondrial; Membrane Proteins; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2014 |
Idarubicin-intensified BUCY2 conditioning regimen improved survival in high-risk acute myeloid, but not lymphocytic leukemia patients undergoing allogeneic hematopoietic stem cell transplantation: A retrospective comparative study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Cyclophosphamide; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Retrospective Studies; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Young Adult | 2016 |
Genomic and transcriptomic profiles and in vitro resistance to mitoxantrone and idarubicin in pediatric acute leukemias.
Topics: Antineoplastic Agents; Cell Survival; Cells, Cultured; Child; Cluster Analysis; Comparative Genomic Hybridization; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Genomics; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2016 |
Improvement of induction remission rate by modifying the dose of idarubicin for relapsed childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Disease-Free Survival; Female; Humans; Idarubicin; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Retrospective Studies; Survival Rate | 2009 |
DNA damage response as a biomarker in treatment of leukemias.
Topics: Adolescent; Adult; Aged; Ataxia Telangiectasia Mutated Proteins; Biomarkers; Cell Cycle Proteins; Child; Daunorubicin; DNA Damage; DNA Topoisomerases; DNA-Binding Proteins; Enzyme Inhibitors; Histones; Humans; Idarubicin; Leukemia, Myeloid, Acute; Mitoxantrone; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Serine-Threonine Kinases; Topoisomerase Inhibitors; Tumor Suppressor Proteins | 2009 |
A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Aspergillus; Busulfan; China; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Idarubicin; Immunosuppressive Agents; Leukemia; Leukemia, Myeloid, Acute; Male; Methylprednisolone; Mucositis; Pneumonia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Premedication; Retrospective Studies; Risk Factors; Semustine; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 2009 |
Successful treatment of hepatic encephalopathy in a patient with acute lymphoblastic leukemia.
Topics: Adult; Alanine Transaminase; Ammonia; Antineoplastic Combined Chemotherapy Protocols; Aspartate Aminotransferases; Bilirubin; Cyclophosphamide; Dexamethasone; Female; Hepatic Encephalopathy; Humans; Idarubicin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vincristine | 2009 |
Fludarabine, cytarabine, granulocyte colony-stimulating factor, and idarubicin (FLAG-IDA) for the treatment of children with poor-prognosis acute leukemia: the Hacettepe experience.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Survival Rate; Treatment Outcome; Vidarabine | 2010 |
Mitoxantrone in first-relapse paediatric ALL: the ALL R3 trial.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Humans; Idarubicin; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Randomized Controlled Trials as Topic; Recurrence; Sample Size; Treatment Outcome | 2010 |
The influence of intracellular idarubicin and daunorubicin levels on drug cytotoxicity in childhood acute leukemia.
Topics: Adolescent; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child; Child, Preschool; Daunorubicin; Flow Cytometry; Humans; Idarubicin; Infant; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrazolium Salts; Thiazoles | 2002 |
CD7+ and CD56+ myeloid/natural killer cell precursor acute leukemia treated with idarubicin and cytosine arabinoside.
Topics: Acute Disease; Aged; Antigens, CD; Antigens, CD7; Antigens, Differentiation, Myelomonocytic; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; CD56 Antigen; Cytarabine; Daunorubicin; Diagnosis, Differential; Etoposide; Fatal Outcome; Humans; Idarubicin; Killer Cells, Natural; Leukemia, Myeloid; Leukemic Infiltration; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Mitoxantrone; Myeloid Cells; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma, Myeloid; Sialic Acid Binding Ig-like Lectin 3 | 2002 |
Treatment of relapsed acute lymphoblastic leukemia after allogeneic bone marrow transplantation with chemotherapy followed by G-CSF-primed donor leukocyte infusion: a prospective study.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Idarubicin; Leukocyte Transfusion; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Recurrence; Tissue Donors; Transplantation, Homologous; Treatment Outcome | 2005 |
FLAG-IDA in the treatment of refractory/relapsed acute leukaemias: single centre study.
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Vidarabine | 2005 |
FLAG-IDA in the treatment of refractory/relapsed adult acute lymphoblastic leukemia.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukocyte Count; Liver; Male; Middle Aged; Mucositis; Platelet Count; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Retrospective Studies; Salvage Therapy; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome; Vidarabine | 2005 |
Feasibility of FLAG-IDA regimen in cases with relapsed/refractory acute leukemia cases.
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Liver Diseases; Male; Mucositis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Stem Cell Transplantation; Transplantation, Homologous; Vidarabine | 2006 |
TLS/FUS-ERG fusion gene in acute lymphoblastic leukemia with t(16;21)(p11;q22) and monitoring of minimal residual disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Chromosome Mapping; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 21; Cytarabine; Etoposide; Exons; Humans; Idarubicin; Infant; Male; Neoplasm, Residual; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; RNA-Binding Protein FUS; Translocation, Genetic; Treatment Outcome | 2005 |
Amsacrine combined with etoposide and high-dose methylprednisolone as salvage therapy in acute lymphoblastic leukemia in children.
Topics: Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Deoxycytidine; Dexamethasone; Drug Evaluation; Drug Synergism; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Infant; Leukemia-Lymphoma, Adult T-Cell; Male; Methylprednisolone; Neoplasm, Residual; Peripheral Blood Stem Cell Transplantation; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Recombinant Proteins; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Thiotepa; Topotecan; Treatment Outcome; Vidarabine; Vinblastine | 2005 |
Itraconazole-enhanced vindesine neurotoxicity in adult acute lymphoblastic leukaemia.
Topics: Adult; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Synergism; Fatal Outcome; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Intestinal Pseudo-Obstruction; Itraconazole; Male; Peripheral Nervous System Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Vincristine; Vindesine | 2007 |
Anthracycline antibiotics induce acute renal tubular toxicity in children with cancer.
Topics: Acetylglucosaminidase; Adolescent; Adult; Albuminuria; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents; Child; Child, Preschool; Creatinine; Daunorubicin; Doxorubicin; Epirubicin; Female; Humans; Idarubicin; Infant; Kidney Diseases; Kidney Tubules, Proximal; Lymphoma, Non-Hodgkin; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Razoxane; Retrospective Studies | 2007 |
In vitro cellular drug resistance in children with relapsed/refractory acute lymphoblastic leukemia.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Disease-Free Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glucocorticoids; Humans; Idarubicin; Ifosfamide; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Salvage Therapy | 1995 |
Preliminary results with 5-aza-2'-deoxycytidine (DAC)-containing chemotherapy in patients with relapsed or refractory acute leukemia. The EORTC Leukemia Cooperative Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Agents; Azacitidine; Decitabine; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction | 1993 |
In vitro anthracycline cross-resistance pattern in childhood acute lymphoblastic leukaemia.
Topics: Aclarubicin; Antibiotics, Antineoplastic; Bone Marrow; Child; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Humans; Idarubicin; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 1995 |
Aggressive chemotherapy for acute leukemia relapsed after transplantation.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Female; Humans; Idarubicin; Italy; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Treatment Outcome; Tretinoin; Vincristine | 1994 |
Low frequency of activity of P-glycoprotein (P-170) in acute lymphoblastic leukemia compared to acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Rhodamine 123; Rhodamines; Survival Analysis | 1995 |
Impact of reinduction regimens for relapsed and refractory acute lymphoblastic leukemia in adults.
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Aspartate-Ammonia Ligase; Clinical Trials as Topic; Cytarabine; Dose-Response Relationship, Drug; Humans; Idarubicin; Incidence; Methotrexate; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Salvage Therapy | 1994 |
Treatment of primary refractory and relapsed acute lymphoblastic leukaemia in children and adults: the GIMEMA/AIEOP experience. Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto. Associazione Italiana Ematologìa ed Ocologia Pediatrica.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Humans; Idarubicin; Infant; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Prospective Studies; Recurrence | 1994 |
Idarubicin in the initial treatment of adults with acute lymphoblastic leukemia: the effect of drug schedule on outcome.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Humans; Idarubicin; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 1993 |
Idarubicin monotherapy in multiply pretreated leukemia patients: response in relation to P-glycoprotein expression.
Topics: Antigens, CD34; ATP Binding Cassette Transporter, Subfamily B, Member 1; Daunorubicin; Fluorescent Dyes; Humans; Idarubicin; Leukemia, Myeloid, Acute; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Rhodamines | 1997 |
The role of idarubicin in adult acute lymphoblastic leukaemia: from drug resistance studies to clinical application.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antigens, CD; Antigens, Neoplasm; Clinical Trials as Topic; Drug Resistance, Neoplasm; Humans; Idarubicin; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured | 1997 |
FLAG-idarubicin and allogeneic stem cell transplantation for Ph-positive ALL beyond first remission.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Male; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Transplantation, Homologous; Treatment Outcome; Vidarabine | 1998 |
Early detection by ultrasound scan of severe post-chemotherapy gut complications in patients with acute leukemia.
Topics: Acute Disease; Adult; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dilatation, Pathologic; Enterocolitis; Etoposide; Female; Gallbladder Diseases; Gastrointestinal Diseases; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Intubation, Gastrointestinal; Leukemia; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Ultrasonography | 1999 |
MTT assay for drug resistance in childhood acute leukemia and effect of cyclosporin and interferon. A preliminary report.
Topics: Antineoplastic Agents; Bone Marrow; Cell Survival; Child; Cyclosporine; Drug Screening Assays, Antitumor; Humans; Idarubicin; Interferon alpha-2; Interferon-alpha; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Predictive Value of Tests; Recombinant Proteins; Tumor Cells, Cultured | 1999 |
Outcome of T cell-depleted transplantation after conditioning with an intensified regimen in patients aged 50 years or more is comparable with that in younger patients.
Topics: Adolescent; Adult; Age Factors; Bone Marrow Transplantation; Cyclophosphamide; Female; Graft vs Host Disease; Humans; Idarubicin; Immunosuppressive Agents; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lymphocyte Depletion; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Survival Rate; T-Lymphocytes | 2000 |
In vitro drug resistance profiles of adult versus childhood acute lymphoblastic leukaemia.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents; Asparaginase; Bone Marrow Cells; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Idarubicin; Ifosfamide; Infant; Leukemia, Prolymphocytic; Leukemia, T-Cell; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Statistics, Nonparametric; Teniposide; Thioguanine; Vincristine | 2000 |
TBI, etoposide and cyclophosphamide as a promising conditioning regimen for BMT in childhood ALL in second remission.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Cyclophosphamide; Cytarabine; Etoposide; Female; Humans; Idarubicin; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation Conditioning; Whole-Body Irradiation | 2000 |
Treatment of relapse after allogeneic bone marrow transplantation with reduced intensity conditioning (FLAG +/- Ida) and second allogeneic stem cell transplant.
Topics: Acute Disease; Adult; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Filgrastim; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; Recurrence; Reoperation; Retrospective Studies; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Vidarabine | 2001 |
Diversity of the apoptotic response to chemotherapy in childhood leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspase 3; Caspases; Child; Child, Preschool; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Daunorubicin; Dexamethasone; Enzyme Induction; Etoposide; Female; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Genes, bcl-2; Genes, p53; Humans; Idarubicin; Infant; Male; Neoplasm Proteins; Neoplastic Stem Cells; Nuclear Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-mdm2; Thioguanine; Tumor Suppressor Protein p53; Vincristine | 2002 |
Treatment of primary refractory or relapsed acute lymphoblastic leukemia (ALL) in children.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Humans; Idarubicin; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction | 1992 |
Anthracyclines and their C-13 alcohol metabolites: growth inhibition and DNA damage following incubation with human tumor cells in culture.
Topics: Antibiotics, Antineoplastic; Cell Division; Daunorubicin; DNA Damage; DNA, Neoplasm; Doxorubicin; Epirubicin; Glioma; Humans; Idarubicin; Leukemia, Myeloid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured | 1992 |
Comparative cellular pharmacology of daunorubicin and idarubicin in human multidrug-resistant leukemia cells.
Topics: Cell Division; Daunorubicin; Drug Resistance; Humans; Idarubicin; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured; Verapamil | 1992 |
Idarubicin in combination with intermediate-dose cytarabine in the treatment of refractory or relapsed acute leukemias.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1989 |