icodextrin and Hernia--Inguinal

In this study, we proposed a peritoneal scintigraphy with a different marker, the 99mTechnetium-Icodextrin, to evaluate the distribution of the dialysate within the peritoneal cavity in peritoneal dialysis (PD) patients.. 99mTc-Icodextrin scintigraphy was performed in 16 PD patients. 0.5 ml of 7.5% Icodextrin solution was labeled with 74 megabecquerel (MBq) of 99mTc and then added to 2,000 ml of dialysate solution (2.5% dextrose). The peritoneum scintigraphy was performed by a SPECT gamma camera with the peritoneal cavity filled and after the complete drainage of the radio compound-dialysate mixture. The images were reviewed for evidence of peritoneal leaks, hernias, loculated fluid collections, and peritoneal membrane adhesions.. Abnormal findings were detected by 99mTc-Icodextrin scintigraphy in 4 (25%) out of 16 patients and included retroperitoneal (n = 1), diaphragmatic (n = 1) and inguinal (n = 1) leakages and peritoneal membrane adhesions (n = 1).. Peritoneum scintigraphy with 99mTc-Icodextrin is a useful method to detect some complications occurring during peritoneal dialysis; it offers excellent imaging to assess these complications.

Topics: Adult; Aged; Animals; Dialysis Solutions; Extravasation of Diagnostic and Therapeutic Materials; Female; Glucans; Glucose; Hernia, Inguinal; Humans; Icodextrin; Kidney Failure, Chronic; Male; Middle Aged; Organotechnetium Compounds; Peritoneal Cavity; Peritoneal Dialysis; Peritoneum; Radiography; Radiopharmaceuticals; Rats; Retroperitoneal Space; Thorax; Tissue Adhesions; Tissue Distribution; Tomography, Emission-Computed, Single-Photon