ici 204,219 has been researched along with Muscle Contraction in 11 studies
zafirlukast: a leukotriene D4 receptor antagonist
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (54.55) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matassa, VG | 1 |
| Maduskuie, TP | 1 |
| Shapiro, HS | 1 |
| Hesp, B | 1 |
| Snyder, DW | 2 |
| Aharony, D | 1 |
| Krell, RD | 2 |
| Keith, RA | 1 |
| Capra, V | 1 |
| Bolla, M | 1 |
| Belloni, PA | 1 |
| Mezzetti, M | 1 |
| Folco, GC | 1 |
| Nicosia, S | 1 |
| Rovati, GE | 1 |
| Lima, LM | 1 |
| de Brito, FC | 1 |
| de Souza, SD | 1 |
| Miranda, AL | 1 |
| Rodrigues, CR | 1 |
| Fraga, CA | 1 |
| Barreiro, EJ | 1 |
| Chang, BS | 1 |
| Chang, JC | 1 |
| Wang, YS | 1 |
| Huang, SC | 1 |
| Bouchelouche, K | 1 |
| Andersen, L | 1 |
| Nordling, J | 1 |
| Horn, T | 1 |
| Bouchelouche, P | 1 |
| Ishimura, M | 1 |
| Kataoka, S | 1 |
| Suda, M | 1 |
| Maeda, T | 1 |
| Hiyama, Y | 1 |
| Gorenne, I | 1 |
| Ortiz, JL | 1 |
| Labat, C | 1 |
| Abram, T | 1 |
| Tudhop, S | 1 |
| Cuthbert, N | 1 |
| Norman, P | 1 |
| Gardiner, P | 1 |
| Morcillo, E | 1 |
| Brink, C | 1 |
| Panettieri, RA | 1 |
| Tan, EM | 1 |
| Ciocca, V | 1 |
| Luttmann, MA | 1 |
| Leonard, TB | 1 |
| Hay, DW | 1 |
| Sakata, K | 1 |
| Bäck, M | 1 |
| Cho, HL | 1 |
| Gilmore, J | 1 |
| Buckner, CK | 1 |
| Fedyna, JS | 1 |
| Robertson, JL | 1 |
| Will, JA | 1 |
| England, DM | 1 |
| Saban, R | 1 |
11 other studies available for ici 204,219 and Muscle Contraction
| Article | Year |
|---|---|
Evolution of a series of peptidoleukotriene antagonists: synthesis and structure/activity relationships of 1,3,5-substituted indoles and indazoles.
Topics: Animals; Dyspnea; Guinea Pigs; In Vitro Techniques; Indazoles; Indoles; Muscle Contraction; Pyrazole | 1990 |
Pharmacological characterization of the cysteinyl-leukotriene antagonists CGP 45715A (iralukast) and CGP 57698 in human airways in vitro.
Topics: Antigens; Benzopyrans; Binding, Competitive; Bronchi; Humans; In Vitro Techniques; Leukotriene D4; L | 1998 |
Novel phthalimide derivatives, designed as leukotriene D(4) receptor antagonists.
Topics: Animals; Anti-Asthmatic Agents; Drug Design; Guinea Pigs; In Vitro Techniques; Indoles; Leukotriene | 2002 |
Cysteinyl leucotriene receptor type 1 mediates contraction in human and guinea-pig oesophagus.
Topics: Acetates; Animals; Atropine; Capsaicin; Carbachol; Cholinergic Agonists; Cyclopropanes; Esophagus; G | 2008 |
The cysteinyl-leukotriene D4 induces cytosolic Ca2+ elevation and contraction of the human detrusor muscle.
Topics: Acetates; Calcium; Cells, Cultured; Cyclopropanes; Cysteine; Cytosol; Dose-Response Relationship, Dr | 2003 |
Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Acetylcholine; Albuter | 2006 |
Antagonism of leukotriene responses in human airways by BAY x7195.
Topics: Antibodies, Anti-Idiotypic; Bronchodilator Agents; Female; Humans; Hydroxy Acids; Immunoglobulin E; | 1995 |
Effects of LTD4 on human airway smooth muscle cell proliferation, matrix expression, and contraction In vitro: differential sensitivity to cysteinyl leukotriene receptor antagonists.
Topics: Asthma; Carbachol; Cells, Cultured; Chromones; Dicarboxylic Acids; DNA Replication; Epidermal Growth | 1998 |
Receptor preferences of cysteinyl-leukotrienes in the guinea pig lung parenchyma.
Topics: Animals; Bronchodilator Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme | 2002 |
Endogenously formed leukotriene C4 activates LTC4 receptors in guinea pig tracheal strips.
Topics: Acetophenones; Animals; Antimetabolites; Benzyl Compounds; Carbachol; Guinea Pigs; Hydroxamic Acids; | 1991 |
An examination of the influence of the epithelium on contractile responses to peptidoleukotrienes and blockade by ICI 204,219 in isolated guinea pig trachea and human intralobar airways.
Topics: Animals; Arachidonate 5-Lipoxygenase; Bronchi; Dose-Response Relationship, Drug; Epithelium; Guinea | 1990 |