Page last updated: 2024-08-26

ici 164384 and Breast Neoplasms

ici 164384 has been researched along with Breast Neoplasms in 102 studies

Research

Studies (102)

Timeframe	Studies, this research(%)	All Research%
pre-1990	11 (10.78)	18.7374
1990's	81 (79.41)	18.2507
2000's	8 (7.84)	29.6817
2010's	2 (1.96)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bélanger, A; Caron, B; Cloutier, J; Dory, YL; Favre, A; Gauthier, S; Labrie, C; Labrie, F; Larouche, D; Leblanc, G; Mailhot, J; Martel, C; Mérand, Y; Ouellet, C; Schwerdtfeger, A; Simard, J	1
Cotnoir-White, D; Gleason, JL; Jutras, I; Kulpa, J; Mader, S; Mendoza-Sanchez, R; Moitessier, N; Pottel, J	1
Berns, EM; Foekens, JA; Jansen, MP; Look, MP; Reijm, EA; Ruigrok-Ritstier, K; Sieuwerts, AM; Sleijfer, S; van Gelder, ME; van Staveren, IL	1
Lopes, P; Trémollières, F	1
Brockdorff, BL; Heiberg, I; Lykkesfeldt, AE	1
Balaguer, P; Boubekeur, N; de Medina, P; Favre, G; Poirot, M; Silvente-Poirot, S	1
Espelund, U; Jepsen, JS; Juncker-Jensen, A; Lykkesfeldt, AE; Ralfkiaer, U; Worm, J	1
Fichtner, I; Frogne, T; Issinger, OG; Lykkesfeldt, AE; Stenvang, J; Yde, CW	1
Fujimoto, N; Katzenellenbogen, BS	1
Coutts, A; Murphy, LC; Murphy, LJ	1
Dekker, A; Dorssers, LC; Foekens, JA; van Agthoven, T; van Agthoven, TL	1
Heitjan, DF; Masamura, S; Santen, RJ; Santner, SJ	1
Gee, JM; Katzenellenbogen, BS; Manning, DL; Montano, MM; Nicholson, RI; Wakeling, AE	1
Pratt, MA; Reed, JC; Teixeira, C	1
Chetrite, G; Nguyen, BL; Pasqualini, JR	1
Dickson, RB; Johnson, GR; Martínez-Lacaci, I; Normanno, N; Plowman, GD; Saceda, M; Salomon, DS	1
el-Tanani, MK; Green, CD	2
Briand, P; Larsen, SS; Lykkesfeldt, AE	1
Auger, S; Labrie, F; Mérand, Y; Pelletier, JD; Poirier, D	1
Fritsch, M; Jiang, SY; Jordan, VC; Pink, JJ	1
Halliwell, B; Wiseman, H	1
Labrie, F; Pelletier, JD; Poirier, D	1
Badia, E; Duchesne, MJ; Fournier-Bidoz, S; Nicolas, JC; Pons, M; Simar-Blanchet, AE; Terouanne, B	1
Musgrove, EA; Sutherland, RL; Sweeney, KJ; Warlters, A; Watts, CK	1
Biberger, C; Holler, E; Koop, R; Leichtl, S; von Angerer, E	1
Jeng, MH; Jiang, SY; Jordan, VC	1
Aronica, SM; Katzenellenbogen, BS; Kraus, WL	1
Johnson, MD; Lykkesfeldt, AE; May, FE; Wakeling, AE; Westley, BR; Wiseman, LR	1
Briand, P; Lykkesfeldt, AE; Madsen, MW	1
Bondy, KL; McDonell, P; Wu, ZF; Zacharewski, TR	1
Krishnan, V; Safe, S; Wang, X	1
Musgrove, EA; Sutherland, RL	1
Bicknell, R; Harris, AL; Toi, M	1
Brünner, N; Clarke, R; Coopman, P; Derocq, D; Garcia, M; Rochefort, H	1
Chalbos, D; Philips, A; Rochefort, H	1
Chalbos, D; Galtier, F; Philips, A; Rochefort, H	1
Sager, R; Webster, L; Zajchowski, DA	1
Manning, DL; Nicholson, RI	1
Ohlsson-Wilhelm, B; Santen, RJ; Santner, SJ	1
Catherino, WH; Jeng, MH; Jordan, VC	1
Hamilton, JA; Lee, CS; Musgrove, EA; Sutherland, RL; Sweeney, KJ; Watts, CK	1
Chetrite, G; Delalonde, L; Pasqualini, JR	1
Christianson, T; Clinton, GM; Hua, W; Rochefort, H; Rougeot, C	1
Clerico, L; de Cupis, A; Favoni, RE; Ferrera, A; Noonan, D; Pirani, P	1
Mark, PJ; Martin, RL; Minchin, RF; Ratajczak, T	1
Kudoh, M	1
Bikle, DD; Gibson, DF; Love-Schimenti, CD; Ratnam, AV	1
Bursch, W; Ellinger, A; Hermann, RS; Kienzl, H; Pandey, S; Sikorska, M; Török, L; Walker, R	1
Chrysogelos, SA; El-Ashry, D; Lauber, AH; Yarden, RI	1
Musgrove, EA; Sarcevic, B; Sutherland, RL; Wilcken, NR	1
Baumann, RJ; Bitonti, AJ; Dumont, JA; Frey, LM; Jarvi, ET; McDonald, IA; Salituro, FG; Wright, PS	1
Ekena, K; Katzenellenbogen, BS; Keller, AL; Krueger, KD; Montano, MM	1
Ben-Jonathan, N; Bigsby, RM; Caperell-Grant, A; Gize, EA; Madhukar, BV; Steinmetz, R; Young, PC	1
Briand, P; Larsen, SS; Lykkesfeldt, AE; Madsen, MW; Reiter, BE	1
Gurpide, E; Markiewicz, L	1
Gustafsson, J; Kuiper, GG; Kushner, PJ; Nilsson, S; Paech, K; Scanlan, TS; Webb, P	1
Adhikarakunnathu, S; Faaland, CA; Thomas, T; Thomas, TJ; Watkins, LF	1
Brown, GM; Hill, SM; Kiefer, T; Ram, PT; Silverman, M; Song, Y	1
Coutts, AS; Murphy, LC	1
Coutts, AS; Davie, JR; Murphy, LC; Samuel, SK; Spencer, VA	1
Musgrove, EA; Prall, OW; Sutherland, RL; Wilcken, NR	1
El Khissiin, A; Laios, I; Larsimont, D; Leclercq, G; Legros, N; Querton, G; Seo, HS	1
Cutler, RE; Hunzicker-Dunn, M; Krett, NL; Maizels, ET; O'Brien, ML; Park-Sarge, OK; Peters, CA; Rosen, ST; Shanmugam, M; Smith, LM	1
Katzenellenbogen, BS; Lazennec, G	1
Poirier, D; Simard, J; Tremblay, MR	1
Egeblad, M; Jäättelä, M; Larsen, SS; Lykkesfeldt, AE	1
Chalbos, D; Cunat, S; Garcia, M; Platet, N; Rochefort, H	1
Dinda, S; Moudgil, V; Sanchez, A	1
Elkak, AE; Mokbel, K	1
Chang, C; Jiang, SY; Jordan, VC; Wolf, DM; Yingling, JM	1
Jiang, SY; Jordan, VC	2
Kangas, L	1
Albaladejo, V; Andre, J; Joly-Pharaboz, MO; Nicolas, B; Zhou-Li, F	1
Chetrite, G; Pasqualini, JR	1
Danielian, PS; Dauvois, S; Parker, MG; White, R	1
Lykkesfeldt, AE; Sørensen, EK	1
Bracke, ME; Mareel, MM; Van Larebeke, NA; Vyncke, BM	1
Wakeling, AE	5
Cho, HS; Katzenellenbogen, BS; NG, PA	1
Arbuckle, N; Danielian, P; Fawell, SE; Parker, MG	1
Bowler, J; Wakeling, AE	1
Nguyen, BL; Pasqualini, JR	1
Bouzubar, N; Davies, P; Gee, JM; Nicholson, RI; Rushmere, NK; Walker, KJ; Wills, RJ	1
Jordan, VC; Murphy, CS; Pink, JJ	1
Katzenellenbogen, BS; Wrenn, CK	1
Gelly, C; Pasqualini, JR	3
Gelly, C; Nguyen, BL; Pasqualini, JR	1
Dickson, RB; Katz, D; Lippman, ME; Shima, TB; Thompson, EW; Wakeling, AE	1
Dufour, JM; Labrie, F; Levesque, C; Merand, Y; Poirier, D; Poulin, R	1
Newboult, E; Peters, SW; Wakeling, AE	1
Musgrove, EA; Sutherland, RL; Wakeling, AE	1
Gottardis, MM; Jeng, MH; Jiang, SY; Jordan, VC	1
May, FE; Wakeling, AE; Westley, BR; Wiseman, LR	1
Cormier, EM; Jordan, VC	1

Reviews

9 review(s) available for ici 164384 and Breast Neoplasms

Article	Year
[Specific estrogen receptor modulators (SERMs)]. Presse medicale (Paris, France : 1983), 2002, Sep-07, Volume: 31, Issue:28 Topics: Adult; Antineoplastic Agents, Hormonal; Bone and Bones; Breast; Breast Neoplasms; Chemotherapy, Adjuvant; Double-Blind Method; Endometrium; Estradiol; Estrogen Antagonists; Estrogen Replacement Therapy; Female; Humans; Lipid Metabolism; Menopause; Middle Aged; Osteoporosis, Postmenopausal; Placebos; Polyunsaturated Alkamides; Postmenopause; Prospective Studies; Quality of Life; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen; Time Factors	2002
Responses to pure antiestrogens (ICI 164384, ICI 182780) in estrogen-sensitive and -resistant experimental and clinical breast cancer. Annals of the New York Academy of Sciences, 1995, Jun-12, Volume: 761 Topics: Breast Neoplasms; Drug Resistance; Estradiol; Estradiol Congeners; Estrogen Antagonists; Female; Fulvestrant; Humans; In Vitro Techniques; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured	1995
[Strategy of drug development for hormone-dependent tumor]. Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:6 Topics: Androgen Antagonists; Antineoplastic Agents, Hormonal; Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Humans; Male; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Prostatic Neoplasms; Tamoxifen	1996
Pure antiestrogens and breast cancer. Current medical research and opinion, 2001, Volume: 17, Issue:4 Topics: Antineoplastic Agents, Hormonal; Benzopyrans; Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Piperidines; Polyunsaturated Alkamides; Propionates	2001
A molecular strategy to control tamoxifen resistant breast cancer. Cancer surveys, 1992, Volume: 14 Topics: Breast Neoplasms; Cell Division; Drug Resistance; Estradiol; Estrogen Antagonists; Estrogens; Humans; Models, Biological; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen; Transfection	1992
Agonistic and antagonistic effects of antiestrogens in different target organs. Acta oncologica (Stockholm, Sweden), 1992, Volume: 31, Issue:2 Topics: Animals; Bone and Bones; Breast Neoplasms; Estradiol; Female; Gene Expression Regulation, Neoplastic; Liver; Mice; Polyunsaturated Alkamides; Rats; Receptors, Estrogen; Tamoxifen; Toremifene; Uterus	1992
Regulatory mechanisms in breast cancer. Steroidal pure antiestrogens. Cancer treatment and research, 1991, Volume: 53 Topics: Animals; Breast Neoplasms; Cell Division; Estradiol; Estrogen Antagonists; Female; Humans; Ovariectomy; Polyunsaturated Alkamides	1991
Development of novel oestrogen-receptor antagonists. Biochemical Society transactions, 1991, Volume: 19, Issue:4 Topics: Animals; Breast Neoplasms; Drug Design; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen	1991
Therapeutic potential of pure antioestrogens in the treatment of breast cancer. The Journal of steroid biochemistry and molecular biology, 1990, Dec-20, Volume: 37, Issue:6 Topics: Antineoplastic Agents; Breast Neoplasms; Estradiol; Estrogen Antagonists; Humans; Polyunsaturated Alkamides; Tumor Cells, Cultured	1990

Other Studies

93 other study(ies) available for ici 164384 and Breast Neoplasms

Article	Year
(S)-(+)-4-[7-(2,2-dimethyl-1-oxopropoxy)-4-methyl-2-[4-[2-(1-piperidinyl)-ethoxy]phenyl]-2H-1-benzopyran-3-yl]-phenyl 2,2-dimethylpropanoate (EM-800): a highly potent, specific, and orally active nonsteroidal antiestrogen. Journal of medicinal chemistry, 1997, Jul-04, Volume: 40, Issue:14 Topics: Administration, Oral; Animals; Benzopyrans; Binding, Competitive; Breast Neoplasms; Cytosol; Diethylstilbestrol; Estradiol; Estrogen Antagonists; Female; Humans; Mice; Molecular Structure; Ovariectomy; Piperidines; Propionates; Raloxifene Hydrochloride; Receptors, Estrogen; Stereoisomerism; Structure-Activity Relationship; Uterus	1997
Design, synthesis and evaluation of antiestrogen and histone deacetylase inhibitor molecular hybrids. Bioorganic & medicinal chemistry, 2015, Dec-15, Volume: 23, Issue:24 Topics: Antineoplastic Agents; Benzamides; Breast; Breast Neoplasms; Cell Line, Tumor; Estradiol; Estrogen Receptor Modulators; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Molecular Docking Simulation; Polyunsaturated Alkamides; Pyridines	2015
Decreased expression of EZH2 is associated with upregulation of ER and favorable outcome to tamoxifen in advanced breast cancer. Breast cancer research and treatment, 2011, Volume: 125, Issue:2 Topics: Antineoplastic Agents, Hormonal; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Fluorescent Antibody Technique; Gene Silencing; Humans; Neoplasm Metastasis; Polycomb Repressive Complex 2; Polymerase Chain Reaction; Polyunsaturated Alkamides; Prognosis; RNA, Messenger; RNA, Small Interfering; Tamoxifen; Transcription Factors; Treatment Outcome	2011
Resistance to different antiestrogens is caused by different multi-factorial changes and is associated with reduced expression of IGF receptor Ialpha. Endocrine-related cancer, 2003, Volume: 10, Issue:4 Topics: Blotting, Western; Breast Neoplasms; Cell Fusion; Cell Line, Tumor; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Flow Cytometry; Fulvestrant; Humans; Insulin-Like Growth Factor Binding Protein 2; Microscopy, Phase-Contrast; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-bcl-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen	2003
The prototypical inhibitor of cholesterol esterification, Sah 58-035 [3-[decyldimethylsilyl]-n-[2-(4-methylphenyl)-1-phenylethyl]propanamide], is an agonist of estrogen receptors. The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:1 Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Estradiol; Humans; Models, Molecular; Organosilicon Compounds; Polyunsaturated Alkamides; Receptors, Estrogen; Sterol O-Acyltransferase; Transcription, Genetic	2006
Insulin-like growth factor binding protein 2 is a marker for antiestrogen resistant human breast cancer cell lines but is not a major growth regulator. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 2006, Volume: 16, Issue:4 Topics: Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Resistance, Neoplasm; Estradiol; Estrogen Antagonists; Estrogens; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Proteins; Oligonucleotide Array Sequence Analysis; Oligonucleotides, Antisense; Polyunsaturated Alkamides; Receptor, IGF Type 1; Tamoxifen	2006
Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitor DMAT. Cancer letters, 2007, Oct-28, Volume: 256, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Benzimidazoles; Breast Neoplasms; Casein Kinase II; Caspases; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-bcl-2; Tamoxifen; Time Factors; Transfection	2007
Alteration in the agonist/antagonist balance of antiestrogens by activation of protein kinase A signaling pathways in breast cancer cells: antiestrogen selectivity and promoter dependence. Molecular endocrinology (Baltimore, Md.), 1994, Volume: 8, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Breast Neoplasms; Cholera Toxin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Estradiol; Estrogen Antagonists; Humans; Immunoblotting; Polyunsaturated Alkamides; Promoter Regions, Genetic; Receptors, Estrogen; Signal Transduction; Transcription, Genetic; Transfection; Tumor Cells, Cultured	1994
Expression of insulin-like growth factor binding proteins by T-47D human breast cancer cells: regulation by progestins and antiestrogens. Breast cancer research and treatment, 1994, Volume: 32, Issue:2 Topics: Breast Neoplasms; Carrier Proteins; Culture Media, Conditioned; Dexamethasone; Estradiol; Estrogen Antagonists; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor Binding Protein 5; Medroxyprogesterone Acetate; Mifepristone; Neoplasm Proteins; Polyunsaturated Alkamides; Pregnenediones; Progesterone; Progestins; Tumor Cells, Cultured	1994
Induction of estrogen independence of ZR-75-1 human breast cancer cells by epigenetic alterations. Molecular endocrinology (Baltimore, Md.), 1994, Volume: 8, Issue:11 Topics: Azacitidine; Breast Neoplasms; Down-Regulation; ErbB Receptors; Estradiol; Estrogen Antagonists; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Keratins; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Proteins; Receptor, ErbB-2; Receptors, Estradiol; Receptors, Progesterone; Tamoxifen; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins	1994
Estrogen deprivation causes estradiol hypersensitivity in human breast cancer cells. The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:10 Topics: Animals; Breast Neoplasms; Cell Division; Cell Line; Dose-Response Relationship, Drug; Drug Implants; Estradiol; Estrogen Antagonists; Female; Humans; Mice; Mice, Nude; Polyunsaturated Alkamides; Receptors, Estrogen; Transplantation, Heterologous; Tumor Cells, Cultured	1995
Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells. Cancer research, 1995, Sep-01, Volume: 55, Issue:17 Topics: Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Doxorubicin; Drug Resistance; Estradiol; Estrogens; Humans; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Tumor Cells, Cultured	1995
Transformation of estrone and estradiol in hormone-dependent and hormone-independent human breast cancer cells. Effects of the antiestrogen ICI 164,384, danazol, and promegestone (R-5020). Breast cancer research and treatment, 1995, Volume: 34, Issue:2 Topics: 17-Hydroxysteroid Dehydrogenases; Biotransformation; Breast Neoplasms; Danazol; Estradiol; Estrogen Antagonists; Estrone; Humans; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Promegestone; Tumor Cells, Cultured	1995
Estrogen and phorbol esters regulate amphiregulin expression by two separate mechanisms in human breast cancer cell lines. Endocrinology, 1995, Volume: 136, Issue:9 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amphiregulin; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Bryostatins; Culture Media, Conditioned; Cycloheximide; Dose-Response Relationship, Drug; EGF Family of Proteins; Estradiol; Estrogen Antagonists; Estrogens; Gene Expression Regulation, Neoplastic; Glycoproteins; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Isoquinolines; Lactones; Macrolides; Piperazines; Polyunsaturated Alkamides; Protein Kinase C; Receptors, Estrogen; RNA, Messenger; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured	1995
Oestrogen-induced genes, pLIV-1 and pS2, respond divergently to other steroid hormones in MCF-7 cells. Molecular and cellular endocrinology, 1995, Apr-28, Volume: 111, Issue:1 Topics: Breast Neoplasms; Dexamethasone; Dihydrotestosterone; Drug Synergism; Estradiol; Estrogen Antagonists; Estrogens; Gene Expression; Gene Expression Regulation, Neoplastic; Hormones; Humans; Polyunsaturated Alkamides; Progesterone; RNA, Messenger; Tumor Cells, Cultured	1995
Human breast cancer cell lines resistant to pure anti-estrogens are sensitive to tamoxifen treatment. International journal of cancer, 1995, May-16, Volume: 61, Issue:4 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Tumor Cells, Cultured	1995
Synthesis and biological activities of thioether derivatives related to the antiestrogens tamoxifen and ICI 164384. The Journal of steroid biochemistry and molecular biology, 1995, Volume: 52, Issue:6 Topics: Animals; Breast Neoplasms; Cell Division; Estradiol; Estrogen Antagonists; Female; Humans; In Vitro Techniques; Molecular Structure; Polyunsaturated Alkamides; Rats; Receptors, Estrogen; Structure-Activity Relationship; Tamoxifen; Tumor Cells, Cultured	1995
An estrogen-independent MCF-7 breast cancer cell line which contains a novel 80-kilodalton estrogen receptor-related protein. Cancer research, 1995, Jun-15, Volume: 55, Issue:12 Topics: Blotting, Western; Breast Neoplasms; Cell Division; Clone Cells; Electrophoresis, Polyacrylamide Gel; Estradiol; Estrogen Antagonists; Female; Humans; Kinetics; Luciferases; Molecular Weight; Polyunsaturated Alkamides; Protein Biosynthesis; Proteins; Receptors, Estrogen; Receptors, Progesterone; Recombinant Proteins; Tamoxifen; Time Factors; Transfection; Tumor Cells, Cultured; Up-Regulation	1995
Tamoxifen and related compounds protect against lipid peroxidation in isolated nuclei: relevance to the potential anticarcinogenic benefits of breast cancer prevention and therapy with tamoxifen? Free radical biology & medicine, 1994, Volume: 17, Issue:5 Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Cell Nucleus; Estradiol; Estrogen Antagonists; Female; Humans; Lipid Peroxidation; Liver; Male; Nafoxidine; Polyunsaturated Alkamides; Rats; Rats, Wistar; Structure-Activity Relationship; Tamoxifen	1994
N-butyl, N-methyl, 11-[3',17' beta-(dihydroxy)-1',3',5'(10')-estratrien-16' alpha-yl]-9(R/S)-bromo undecanamide: synthesis and 17 beta-HSD inhibiting, estrogenic and antiestrogenic activities. Steroids, 1994, Volume: 59, Issue:9 Topics: 17-Hydroxysteroid Dehydrogenases; Breast Neoplasms; Estradiol; Estrogen Antagonists; Estrone; Humans; Methods; Polyunsaturated Alkamides; Tumor Cells, Cultured	1994
Hydroxytamoxifen induces a rapid and irreversible inactivation of an estrogenic response in an MCF-7-derived cell line. Cancer research, 1994, Nov-15, Volume: 54, Issue:22 Topics: Base Sequence; Breast Neoplasms; Cell Division; Cell Line; Enzyme Induction; Estradiol; Estrogen Antagonists; Gene Expression Regulation, Enzymologic; Humans; Luciferases; Molecular Sequence Data; Plasmids; Polyunsaturated Alkamides; Receptors, Estrogen; RNA, Messenger; Tamoxifen; Transfection; Tumor Cells, Cultured	1994
Antiestrogen regulation of cell cycle progression and cyclin D1 gene expression in MCF-7 human breast cancer cells. Breast cancer research and treatment, 1994, Volume: 31, Issue:1 Topics: Animals; Breast Neoplasms; Cell Cycle; Cell Division; Cell Line; Culture Media, Serum-Free; Cyclin D1; Cyclins; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Mice; Mice, Nude; Oncogene Proteins; Polyunsaturated Alkamides; Tamoxifen; Time Factors; Transplantation, Heterologous; Tumor Cells, Cultured	1994
1-Carbamoylalkyl-2-phenylindoles: relationship between side chain structure and estrogen antagonism. The Journal of steroid biochemistry and molecular biology, 1994, Volume: 49, Issue:1 Topics: Animals; Breast Neoplasms; Cell Division; Estradiol; Estrogen Antagonists; Female; HeLa Cells; Humans; Indoles; Mice; Organ Size; Polyunsaturated Alkamides; Radioligand Assay; Receptors, Estrogen; Sequence Deletion; Structure-Activity Relationship; Tamoxifen; Transcriptional Activation; Tumor Cells, Cultured; Uterus	1994
Paradoxical regulation of estrogen-dependent growth factor gene expression in estrogen receptor (ER)-negative human breast cancer cells stably expressing ER. Cancer letters, 1994, Jul-29, Volume: 82, Issue:2 Topics: Breast Neoplasms; Cell Division; Estradiol; Female; Gene Expression Regulation, Neoplastic; Humans; Lymphotoxin-alpha; Polyunsaturated Alkamides; Receptors, Estrogen; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Up-Regulation	1994
Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription. Proceedings of the National Academy of Sciences of the United States of America, 1994, Aug-30, Volume: 91, Issue:18 Topics: Adenylyl Cyclases; Animals; Base Sequence; Breast Neoplasms; Cells, Cultured; Cyclic AMP; Estradiol; Female; Gene Expression Regulation; Humans; In Vitro Techniques; Molecular Sequence Data; Oligodeoxyribonucleotides; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Signal Transduction; Tamoxifen; Transcription, Genetic; Tumor Cells, Cultured; Uterus	1994
Type I IGF receptor and acquired tamoxifen resistance in oestrogen-responsive human breast cancer cells. European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:16 Topics: Breast Neoplasms; Cell Adhesion; Cell Division; Dose-Response Relationship, Drug; Drug Resistance; Estradiol; Estrogen Antagonists; Estrogens; Female; Humans; Insulin-Like Growth Factor I; Polyunsaturated Alkamides; Receptor, IGF Type 1; Tamoxifen; Tumor Cells, Cultured	1993
Altered expression of estrogen-regulated genes in a tamoxifen-resistant and ICI 164,384 and ICI 182,780 sensitive human breast cancer cell line, MCF-7/TAMR-1. Cancer research, 1994, Mar-15, Volume: 54, Issue:6 Topics: Animals; Base Sequence; Breast Neoplasms; Cell Division; Chloramphenicol O-Acetyltransferase; Culture Media; Drug Resistance; Drug Screening Assays, Antitumor; Estradiol; Estrogen Antagonists; Estrogens; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tamoxifen; Time Factors; Transfection; Tumor Cells, Cultured	1994
Antiestrogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on 17 beta-estradiol-induced pS2 expression. Cancer research, 1994, May-15, Volume: 54, Issue:10 Topics: Base Sequence; Breast Neoplasms; Dioxins; Estradiol; Firefly Luciferin; Genes, Reporter; HeLa Cells; Humans; Molecular Sequence Data; Neoplasm Proteins; Polychlorinated Dibenzodioxins; Polyunsaturated Alkamides; Proteins; Receptors, Aryl Hydrocarbon; Tamoxifen; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins	1994
Estrogen receptor-Sp1 complexes mediate estrogen-induced cathepsin D gene expression in MCF-7 human breast cancer cells. The Journal of biological chemistry, 1994, Jun-03, Volume: 269, Issue:22 Topics: Adenosine Triphosphate; Base Sequence; Breast Neoplasms; Cathepsin D; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; Cloning, Molecular; DNA-Binding Proteins; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Molecular Sequence Data; Nuclear Proteins; Oligonucleotides, Antisense; Phosphorus Radioisotopes; Polyunsaturated Alkamides; Receptors, Estrogen; Recombinant Fusion Proteins; Sp1 Transcription Factor; Sulfuric Acid Esters; Thymidine Kinase; Transfection; Tumor Cells, Cultured	1994
Effects of the progestin antagonist RU 486 on T-47D breast cancer cell cycle kinetics and cell cycle regulatory genes. Biochemical and biophysical research communications, 1993, Sep-30, Volume: 195, Issue:3 Topics: Breast Neoplasms; Cell Cycle; Cyclin D1; Cyclins; Dose-Response Relationship, Drug; Estradiol; Humans; Mifepristone; Oncogene Proteins; Polyunsaturated Alkamides; Pregnenediones; Progesterone Congeners; Progestins; Proto-Oncogene Proteins c-myc; RNA, Messenger; S Phase; Tumor Cells, Cultured	1993
cDNA transfection followed by the isolation of a MCF-7 breast cell line resistant to tamoxifen in vitro and in vivo. British journal of cancer, 1993, Volume: 68, Issue:6 Topics: Animals; Breast Neoplasms; Cloning, Molecular; Culture Media, Conditioned; DNA, Complementary; DNA, Neoplasm; DNA, Recombinant; Drug Resistance; Estradiol; Estrogen Antagonists; Estrogens; Female; Growth Substances; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen; Transfection; Tumor Cells, Cultured; Tumor Stem Cell Assay	1993
Anti-proliferative and anti-estrogenic effects of ICI 164,384 and ICI 182,780 in 4-OH-tamoxifen-resistant human breast-cancer cells. International journal of cancer, 1994, Jan-15, Volume: 56, Issue:2 Topics: Antineoplastic Agents; Breast Neoplasms; Cathepsin D; Cell Division; Drug Resistance; Estradiol; Estrogen Antagonists; Estrogens; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Proteins; Receptors, Estrogen; Tamoxifen; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins	1994
Estradiol increases and anti-estrogens antagonize the growth factor-induced activator protein-1 activity in MCF7 breast cancer cells without affecting c-fos and c-jun synthesis. The Journal of biological chemistry, 1993, Jul-05, Volume: 268, Issue:19 Topics: Breast Neoplasms; Chloramphenicol O-Acetyltransferase; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Female; Genes, fos; Genes, jun; Humans; Insulin-Like Growth Factor I; Kinetics; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptors, Estrogen; Recombinant Fusion Proteins; RNA, Messenger; Tamoxifen; Thymidine Kinase; Time Factors; Transfection; Tumor Cells, Cultured	1993
Synthetic antiestrogens modulate induction of pS2 and cathepsin-D messenger ribonucleic acid by growth factors and adenosine 3',5'-monophosphate in MCF7 cells. Endocrinology, 1993, Volume: 133, Issue:2 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Breast Neoplasms; Cathepsin D; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Growth Substances; Humans; Insulin-Like Growth Factor I; Neoplasm Proteins; Polyunsaturated Alkamides; Proteins; RNA, Messenger; Tamoxifen; Tetradecanoylphorbol Acetate; Transcription, Genetic; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins	1993
Estrogen inhibits the growth of estrogen receptor-negative, but not estrogen receptor-positive, human mammary epithelial cells expressing a recombinant estrogen receptor. Cancer research, 1993, Oct-15, Volume: 53, Issue:20 Topics: Animals; Breast; Breast Neoplasms; Cell Cycle; Cell Division; Cell Line; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Estradiol; Estrogen Antagonists; Female; Humans; Kinetics; Mice; Mice, Nude; Polyunsaturated Alkamides; Receptors, Estrogen; Recombinant Proteins; Tamoxifen; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured	1993
Isolation of pMGT1: a gene that is repressed by oestrogen and increased by antioestrogens and antiprogestins. European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:5 Topics: Breast Neoplasms; DNA, Neoplasm; Down-Regulation; Estradiol; Estrogen Antagonists; Estrogens; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Mifepristone; Polyunsaturated Alkamides; Progestins; Tamoxifen; Tumor Cells, Cultured	1993
Estrone sulfate promotes human breast cancer cell replication and nuclear uptake of estradiol in MCF-7 cell cultures. International journal of cancer, 1993, Apr-22, Volume: 54, Issue:1 Topics: Biological Transport; Breast Neoplasms; Cell Division; Cell Nucleus; Cells, Cultured; Estradiol; Estrone; Female; Humans; In Vitro Techniques; Neoplasm Proteins; Polyunsaturated Alkamides; Proteins; Receptors, Progesterone; S Phase; Sulfatases; Trefoil Factor-1; Tumor Suppressor Proteins	1993
Norgestrel and gestodene stimulate breast cancer cell growth through an oestrogen receptor mediated mechanism. British journal of cancer, 1993, Volume: 67, Issue:5 Topics: Base Sequence; Breast Neoplasms; Cell Division; Estradiol; Estrogens; Female; Gene Expression; Humans; In Vitro Techniques; Mifepristone; Molecular Sequence Data; Norgestrel; Norpregnenes; Polyunsaturated Alkamides; Promoter Regions, Genetic; Receptors, Estrogen; Regulatory Sequences, Nucleic Acid; Transcription, Genetic; Tumor Cells, Cultured	1993
Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression. Molecular and cellular biology, 1993, Volume: 13, Issue:6 Topics: Breast Neoplasms; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Cycle; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Cyclins; DNA, Neoplasm; Estradiol; Estrogen Antagonists; Female; G1 Phase; Gene Expression Regulation, Neoplastic; Genes, myc; Growth Substances; Histones; Humans; Insulin; Kinetics; Mifepristone; Polyunsaturated Alkamides; Pregnenediones; Progesterone Congeners; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Proteins; RNA, Messenger; Time Factors; Transcription, Genetic; Tumor Cells, Cultured	1993
Comparative effect of embryonic mouse fibroblasts (Balb/c-3T3) on the proliferation of hormone-dependent (T-47D) and hormone-independent (MDA-MB-231) human breast cancer cell lines. Breast cancer research and treatment, 1993, Volume: 25, Issue:1 Topics: Animals; Breast Neoplasms; Cell Division; Cell Extracts; Culture Media, Conditioned; DNA, Neoplasm; Drug Antagonism; Estradiol; Estrogen Antagonists; Fibroblasts; Humans; Mice; Mice, Inbred BALB C; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Receptors, Progesterone; Tumor Cells, Cultured	1993
SKOV3 ovarian carcinoma cells have functional estrogen receptor but are growth-resistant to estrogen and antiestrogens. The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:3-4 Topics: Blotting, Northern; Breast Neoplasms; Carcinoma; Cathepsin D; Cell Division; Drug Resistance, Neoplasm; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Genes, myc; Humans; Ovarian Neoplasms; Polyunsaturated Alkamides; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tamoxifen; Tumor Cells, Cultured	1995
Comparison between novel steroid-like and conventional nonsteroidal antioestrogens in inhibiting oestradiol- and IGF-I-induced proliferation of human breast cancer-derived cells. British journal of pharmacology, 1995, Volume: 116, Issue:5 Topics: Base Sequence; Blotting, Western; Breast Neoplasms; Cell Division; Culture Media, Conditioned; DNA; Estradiol; Estrogen Antagonists; Fulvestrant; Humans; Insulin-Like Growth Factor I; Molecular Sequence Data; Polyunsaturated Alkamides; RNA, Messenger; Steroids; Tamoxifen; Tumor Cells, Cultured	1995
Cyclosporin A potentiates estradiol-induced expression of the cathepsin D gene in MCF7 breast cancer cells. Biochemical and biophysical research communications, 1996, Mar-07, Volume: 220, Issue:1 Topics: Breast Neoplasms; Cathepsin D; Cyclosporine; Drug Synergism; Estradiol; Estrogen Antagonists; Female; Gene Expression; Humans; Polyunsaturated Alkamides; Receptors, Estradiol; RNA, Messenger; Transcriptional Activation; Tumor Cells, Cultured	1996
Antiestrogen potentiation of antiproliferative effects of vitamin D3 analogues in breast cancer cells. Cancer research, 1996, Jun-15, Volume: 56, Issue:12 Topics: Antineoplastic Agents; Breast Neoplasms; Calcitriol; Cell Division; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Estradiol; Estrogen Antagonists; Female; Humans; Neoplasm Proteins; Polyunsaturated Alkamides; Receptors, Calcitriol; RNA, Messenger; Tumor Cells, Cultured	1996
Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy. Carcinogenesis, 1996, Volume: 17, Issue:8 Topics: Autophagy; Breast Neoplasms; Cell Cycle; Cell Death; Estradiol; Estrogen Antagonists; Humans; L-Lactate Dehydrogenase; Polyunsaturated Alkamides; Tamoxifen; Trypan Blue; Tumor Cells, Cultured	1996
Bimodal regulation of epidermal growth factor receptor by estrogen in breast cancer cells. Endocrinology, 1996, Volume: 137, Issue:7 Topics: Base Sequence; Breast Neoplasms; Cell Line; Cell Nucleus; Consensus Sequence; Cycloheximide; Dactinomycin; Down-Regulation; ErbB Receptors; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Models, Biological; Molecular Sequence Data; Polyunsaturated Alkamides; Promoter Regions, Genetic; RNA, Messenger; Time Factors; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation	1996
Differential effects of retinoids and antiestrogens on cell cycle progression and cell cycle regulatory genes in human breast cancer cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1996, Volume: 7, Issue:1 Topics: Breast Neoplasms; Cell Cycle; Cell Division; Cyclin D1; Cyclin-Dependent Kinases; Cyclins; Estradiol; Estrogen Antagonists; Female; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Oncogene Proteins; Phosphorylation; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-myc; Retinoids; Time Factors; Tumor Cells, Cultured	1996
Depletion of estrogen receptor in human breast tumor cells by a novel substituted indole that does not bind to the hormone binding domain. The Journal of steroid biochemistry and molecular biology, 1996, Volume: 58, Issue:1 Topics: Base Sequence; Binding, Competitive; Breast Neoplasms; Cell Extracts; Cell Nucleus; DNA; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Gene Expression; Genes, Reporter; Humans; Indoles; Molecular Sequence Data; Polyunsaturated Alkamides; Receptors, Estradiol; Receptors, Estrogen; RNA, Messenger; RNA, Neoplasm; Time Factors; Transcription Factors; Tumor Cells, Cultured	1996
Human estrogen receptor ligand activity inversion mutants: receptors that interpret antiestrogens as estrogens and estrogens as antiestrogens and discriminate among different antiestrogens. Molecular endocrinology (Baltimore, Md.), 1996, Volume: 10, Issue:3 Topics: 3T3 Cells; Animals; Breast Neoplasms; CHO Cells; Cricetinae; Cricetulus; Estradiol; Estrogen Antagonists; Estrogens; Female; Humans; Ligands; Mice; Neoplasms, Hormone-Dependent; Point Mutation; Polyunsaturated Alkamides; Promoter Regions, Genetic; Protein Binding; Receptors, Estrogen; Recombinant Fusion Proteins; Structure-Activity Relationship; Substrate Specificity; Tamoxifen; Transcription, Genetic; Tumor Cells, Cultured	1996
Novel estrogenic action of the pesticide residue beta-hexachlorocyclohexane in human breast cancer cells. Cancer research, 1996, Dec-01, Volume: 56, Issue:23 Topics: Adenocarcinoma; Animals; Binding, Competitive; Breast Neoplasms; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogens; Female; Gene Expression Regulation, Neoplastic; Hexachlorocyclohexane; Humans; Male; Mice; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Pesticide Residues; Pituitary Neoplasms; Polyunsaturated Alkamides; Promoter Regions, Genetic; Protein Biosynthesis; Proteins; Rats; Receptors, Estrogen; Recombinant Fusion Proteins; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins	1996
Interaction between estradiol and cAMP in the regulation of specific gene expression. Molecular and cellular endocrinology, 1996, Nov-29, Volume: 124, Issue:1-2 Topics: 1-Methyl-3-isobutylxanthine; Breast Neoplasms; Carcinoma; Cholera Toxin; Cyclic AMP; Cycloheximide; Estradiol; Estrogen Antagonists; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Phosphodiesterase Inhibitors; Polyunsaturated Alkamides; Protein Synthesis Inhibitors; Proteins; Receptors, Estradiol; RNA, Messenger; RNA, Neoplasm; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins	1996
Estrogen receptor messenger RNA splice variants are not involved in antiestrogen resistance in sublines of MCF-7 human breast cancer cells. Cancer research, 1997, Feb-15, Volume: 57, Issue:4 Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Drug Resistance, Neoplasm; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Genetic Vectors; Humans; Polyunsaturated Alkamides; Receptors, Estrogen; RNA Splicing; RNA, Messenger; RNA, Neoplasm; Tamoxifen; Transfection; Tumor Cells, Cultured	1997
Estrogenic and progestagenic activities of physiologic and synthetic androgens, as measured by in vitro bioassays. Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:4 Topics: Adenocarcinoma; Alkaline Phosphatase; Androgen Antagonists; Androgens; Breast Neoplasms; Cyproterone Acetate; Endometrial Neoplasms; Estradiol; Estrogen Antagonists; Female; Flutamide; Gonanes; Humans; Mifepristone; Polyunsaturated Alkamides; Progestins; Tamoxifen; Testosterone; Testosterone Congeners; Tumor Cells, Cultured	1997
Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites. Science (New York, N.Y.), 1997, Sep-05, Volume: 277, Issue:5331 Topics: Animals; Breast Neoplasms; Cell Line; Diethylstilbestrol; Enhancer Elements, Genetic; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; HeLa Cells; Humans; Ligands; Piperidines; Polyunsaturated Alkamides; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Tamoxifen; Transcription Factor AP-1; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Uterus	1997
Induction of p21 (CIP1/WAF1/SID1) by estradiol in a breast epithelial cell line transfected with the recombinant estrogen receptor gene: a possible mechanism for a negative regulatory role of estradiol. Breast cancer research and treatment, 1998, Volume: 47, Issue:2 Topics: Breast; Breast Neoplasms; Cell Division; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Epithelial Cells; Estradiol; Female; Humans; Polyunsaturated Alkamides; Receptors, Estrogen; RNA, Messenger; Transfection; Tumor Suppressor Protein p53	1998
Estrogen receptor transactivation in MCF-7 breast cancer cells by melatonin and growth factors. Molecular and cellular endocrinology, 1998, Jun-25, Volume: 141, Issue:1-2 Topics: Blotting, Western; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Female; Growth Substances; Humans; Insulin; Melatonin; Pertussis Toxin; Phosphorylation; Polyunsaturated Alkamides; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Virulence Factors, Bordetella	1998
Elevated mitogen-activated protein kinase activity in estrogen-nonresponsive human breast cancer cells. Cancer research, 1998, Sep-15, Volume: 58, Issue:18 Topics: Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Estradiol; Estrogen Antagonists; Female; Humans; Neoplasm Proteins; Phenotype; Phosphorylation; Polyunsaturated Alkamides; Receptors, Estrogen; Tumor Cells, Cultured	1998
Estrogen regulates the association of intermediate filament proteins with nuclear DNA in human breast cancer cells. The Journal of biological chemistry, 1998, Oct-30, Volume: 273, Issue:44 Topics: Breast Neoplasms; Cell Nucleus; Cisplatin; DNA Adducts; DNA, Neoplasm; Estradiol; Estrogen Antagonists; Estrogens; Humans; Intermediate Filament Proteins; Keratins; Polyunsaturated Alkamides; Tumor Cells, Cultured	1998
Inducible overexpression of cyclin D1 in breast cancer cells reverses the growth-inhibitory effects of antiestrogens. Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:6 Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Division; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Drug Resistance, Neoplasm; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Polyunsaturated Alkamides; Proto-Oncogene Proteins; S Phase; Tamoxifen; Tumor Cells, Cultured; Zinc Sulfate	1997
Estrogenic and anti-estrogenic regulation of estrogen receptor in MCF-7 breast-cancer cells: comparison of immunocytochemical data with biochemical measurements. International journal of cancer, 1998, Dec-09, Volume: 78, Issue:6 Topics: Breast Neoplasms; Cycloheximide; Dactinomycin; Down-Regulation; Estradiol; Estrogen Antagonists; Estrogens; Humans; Immunoenzyme Techniques; Immunohistochemistry; Kinetics; Okadaic Acid; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen; Time Factors; Tumor Cells, Cultured	1998
Regulation of protein kinase C delta by estrogen in the MCF-7 human breast cancer cell line. Molecular and cellular endocrinology, 1999, Feb-25, Volume: 148, Issue:1-2 Topics: Animals; Breast Neoplasms; Corpus Luteum; Estradiol; Estrogen Antagonists; Estrogens; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Granulosa Cells; Humans; Isoenzymes; Polyunsaturated Alkamides; Protamine Kinase; Protein Kinase C; Protein Kinase C-delta; Rabbits; Rats; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured	1999
Expression of human estrogen receptor using an efficient adenoviral gene delivery system is able to restore hormone-dependent features to estrogen receptor-negative breast carcinoma cells. Molecular and cellular endocrinology, 1999, Mar-25, Volume: 149, Issue:1-2 Topics: Adenoviridae; Base Sequence; Breast Neoplasms; Cell Division; DNA Primers; Estradiol; Estrogen Antagonists; Female; Gene Expression; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Kinetics; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Receptors, Estrogen; Recombinant Proteins; Tumor Cells, Cultured	1999
Parallel solid-phase synthesis of a model library of 7alpha-alkylamide estradiol derivatives as potential estrogen receptor antagonists. Bioorganic & medicinal chemistry letters, 1999, Oct-04, Volume: 9, Issue:19 Topics: Amides; Breast Neoplasms; Cell Division; Estradiol; Estrogen Receptor Modulators; Humans; Molecular Structure; Polyunsaturated Alkamides; Receptors, Estrogen; Tumor Cells, Cultured	1999
Acquired antiestrogen resistance in MCF-7 human breast cancer sublines is not accomplished by altered expression of receptors in the ErbB-family. Breast cancer research and treatment, 1999, Volume: 58, Issue:1 Topics: Blotting, Northern; Blotting, Western; Breast Neoplasms; DNA Primers; Drug Resistance, Neoplasm; Enzyme-Linked Immunosorbent Assay; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Polyunsaturated Alkamides; Receptor, ErbB-2; Reverse Transcriptase Polymerase Chain Reaction; Tamoxifen; Tumor Cells, Cultured	1999
Unliganded and liganded estrogen receptors protect against cancer invasion via different mechanisms. Molecular endocrinology (Baltimore, Md.), 2000, Volume: 14, Issue:7 Topics: Amino Acid Sequence; Breast Neoplasms; Calcium-Binding Proteins; Calreticulin; Cell Movement; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Humans; Ligands; Molecular Sequence Data; Neoplasm Invasiveness; Polyunsaturated Alkamides; Promoter Regions, Genetic; Receptors, Estrogen; Response Elements; Ribonucleoproteins; Sequence Deletion; Transcriptional Activation; Tumor Cells, Cultured; Zinc Fingers	2000
Estrogen-like effects of thyroid hormone on the regulation of tumor suppressor proteins, p53 and retinoblastoma, in breast cancer cells. Oncogene, 2002, Jan-24, Volume: 21, Issue:5 Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Division; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Female; Humans; Kinetics; Phosphorylation; Polyunsaturated Alkamides; Receptors, Estrogen; Retinoblastoma Protein; Triiodothyronine; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Up-Regulation	2002
An estrogen receptor positive MCF-7 clone that is resistant to antiestrogens and estradiol. Molecular and cellular endocrinology, 1992, Volume: 90, Issue:1 Topics: Breast Neoplasms; Cell Division; Clone Cells; DNA, Neoplasm; Drug Resistance; ErbB Receptors; Estradiol; Estrogen Antagonists; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Polymerase Chain Reaction; Polyunsaturated Alkamides; Progesterone; Receptors, Estrogen; Recombinant Fusion Proteins; Signal Transduction; Tamoxifen; Transfection; Transforming Growth Factor alpha; Tumor Cells, Cultured	1992
Antiestrogens prevent the stimulatory effects of L-triiodothyronine on cell proliferation. Endocrinology, 1992, Volume: 130, Issue:3 Topics: Breast Neoplasms; Cell Division; DNA, Neoplasm; Estradiol; Estrogen Antagonists; Female; Humans; Insulin-Like Growth Factor I; Pituitary Neoplasms; Polyunsaturated Alkamides; Receptors, Estrogen; Receptors, Thyroid Hormone; RNA, Messenger; Tamoxifen; Transcription, Genetic; Triiodothyronine; Tumor Cells, Cultured	1992
Growth regulation of estrogen receptor-negative breast cancer cells transfected with complementary DNAs for estrogen receptor. Journal of the National Cancer Institute, 1992, Apr-15, Volume: 84, Issue:8 Topics: Base Sequence; Breast Neoplasms; Cell Division; DNA; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation, Neoplastic; Genetic Techniques; Humans; Molecular Sequence Data; Polyunsaturated Alkamides; Receptors, Estrogen; Transfection; Tumor Cells, Cultured	1992
Effect of embryonic mouse cells BALB/c-3T3 on the proliferation of the human mammary cancer cell line T-47D. The Journal of steroid biochemistry and molecular biology, 1992, Volume: 41, Issue:3-8 Topics: 3T3 Cells; Animals; Breast Neoplasms; Cell Communication; Cell Division; DNA Replication; Estradiol; Estrogen Antagonists; Female; Humans; Kinetics; Mice; Mice, Inbred BALB C; Polyunsaturated Alkamides	1992
Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover. Proceedings of the National Academy of Sciences of the United States of America, 1992, May-01, Volume: 89, Issue:9 Topics: Animals; Breast Neoplasms; Cells, Cultured; DNA-Binding Proteins; Down-Regulation; Estradiol; Gene Expression; Humans; In Vitro Techniques; Mice; Polyunsaturated Alkamides; Receptors, Estrogen; RNA, Messenger; Transfection; Tumor Cells, Cultured	1992
Effect of estrogen and antiestrogens on cell proliferation and synthesis of secreted proteins in the human breast cancer cell line MCF-7 and a tamoxifen resistant variant subline, AL-1. Acta oncologica (Stockholm, Sweden), 1992, Volume: 31, Issue:2 Topics: Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Drug Resistance; Estradiol; Estrogen Antagonists; Female; Humans; Molecular Weight; Neoplasm Proteins; Polyunsaturated Alkamides; Tamoxifen; Tumor Cells, Cultured	1992
Retinoic acid modulates both invasion and plasma membrane ruffling of MCF-7 human mammary carcinoma cells in vitro. British journal of cancer, 1991, Volume: 63, Issue:6 Topics: Animals; Breast Neoplasms; Cell Aggregation; Cell Division; Cell Line; Cell Membrane; Chick Embryo; Dexamethasone; Estradiol; Estrogen Antagonists; Female; Humans; Myocardium; Neoplasm Invasiveness; Polyunsaturated Alkamides; Receptors, Cell Surface; Tretinoin; Triiodothyronine	1991
Differential regulation of gene expression by estrogen in estrogen growth-independent and -dependent MCF-7 human breast cancer cell sublines. Molecular endocrinology (Baltimore, Md.), 1991, Volume: 5, Issue:9 Topics: 1-Methyl-3-isobutylxanthine; Breast Neoplasms; Cell Line, Transformed; Clone Cells; Down-Regulation; Epidermal Growth Factor; Estradiol; Female; Gene Expression Regulation; Humans; Polyunsaturated Alkamides; Receptors, Cell Surface; Receptors, Estradiol; Receptors, Progesterone; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic	1991
Role of ligand in oestrogen-receptor function. Biochemical Society transactions, 1991, Volume: 19, Issue:4 Topics: Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Humans; Ligands; Molecular Structure; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Receptors, Estrogen; Tamoxifen	1991
Estrone sulfatase activity and effect of antiestrogens on transformation of estrone sulfate in hormone-dependent vs. independent human breast cancer cell lines. Breast cancer research and treatment, 1991, Volume: 18, Issue:2 Topics: Breast Neoplasms; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogens; Humans; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Sulfatases; Tamoxifen; Tumor Cells, Cultured	1991
Estrogen deprivation in breast cancer. Clinical, experimental, and biological aspects. Annals of the New York Academy of Sciences, 1990, Volume: 595 Topics: Breast Neoplasms; Buserelin; Estradiol; Estrogen Antagonists; Female; Gonadotropin-Releasing Hormone; Goserelin; Humans; Menopause; Polyunsaturated Alkamides; Tamoxifen	1990
Characterization of a receptor-negative, hormone-nonresponsive clone derived from a T47D human breast cancer cell line kept under estrogen-free conditions. Cancer research, 1990, Nov-15, Volume: 50, Issue:22 Topics: Blotting, Northern; Breast Neoplasms; Cell Division; Clone Cells; Cytidine; DNA Fingerprinting; DNA, Neoplasm; ErbB Receptors; Estradiol; Gene Expression; Humans; In Vitro Techniques; Polyunsaturated Alkamides; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tamoxifen; Transforming Growth Factor alpha; Transforming Growth Factor beta; Tumor Cells, Cultured	1990
Cross-linking of estrogen receptor to chromatin in intact MCF-7 human breast cancer cells: optimization and effect of ligand. Molecular endocrinology (Baltimore, Md.), 1990, Volume: 4, Issue:11 Topics: Breast Neoplasms; Centrifugation, Density Gradient; Chromatin; Cross-Linking Reagents; DNA; Estradiol; Estrogen Antagonists; Formaldehyde; Humans; Ligands; Polyunsaturated Alkamides; Receptors, Estrogen; Ribonucleoproteins; RNA Polymerase II; Tumor Cells, Cultured; Ultraviolet Rays	1990
Biological response of the anti-estrogen ICI 164,384 in human hormone-dependent and hormone-independent mammary cancer cell lines. Cancer letters, 1990, Apr-20, Volume: 50, Issue:2 Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; DNA, Neoplasm; Estradiol; Estrogen Antagonists; Female; Humans; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Receptors, Progesterone; Thymidine; Tumor Cells, Cultured	1990
Metabolism and biologic response of estrogen sulfates in hormone-dependent and hormone-independent mammary cancer cell lines. Effect of antiestrogens. Annals of the New York Academy of Sciences, 1990, Volume: 595 Topics: Breast Neoplasms; Estradiol; Estriol; Estrone; Female; Humans; Menstruation; Polyunsaturated Alkamides; Progesterone; Receptors, Progesterone; Tamoxifen; Tumor Cells, Cultured	1990
Novel pure antiestrogens. Mode of action and therapeutic prospects. Annals of the New York Academy of Sciences, 1990, Volume: 595 Topics: Animals; Animals, Newborn; Breast Neoplasms; Cell Division; Estradiol; Estrogen Antagonists; Female; Polyunsaturated Alkamides; Rats; Structure-Activity Relationship; Tamoxifen; Tumor Cells, Cultured; Uterus	1990
ICI 164,384, a pure antagonist of estrogen-stimulated MCF-7 cell proliferation and invasiveness. Cancer research, 1989, Dec-15, Volume: 49, Issue:24 Pt 1 Topics: Basement Membrane; Binding, Competitive; Breast Neoplasms; Cell Cycle; Estradiol; Estrogen Antagonists; Humans; Neoplasm Invasiveness; Polyunsaturated Alkamides; Pyrrolidines; Receptors, Estrogen; Stimulation, Chemical; Tamoxifen; Thiophenes; Tumor Cells, Cultured	1989
Antiestrogenic properties of keoxifene, trans-4-hydroxytamoxifen, and ICI 164384, a new steroidal antiestrogen, in ZR-75-1 human breast cancer cells. Breast cancer research and treatment, 1989, Volume: 14, Issue:1 Topics: Binding, Competitive; Breast Neoplasms; Cell Division; Dexamethasone; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Estrogen Antagonists; Humans; Piperidines; Polyunsaturated Alkamides; Raloxifene Hydrochloride; Receptors, Estrogen; Tamoxifen; Time Factors; Tumor Cells, Cultured	1989
The potential for a novel pure anti-oestrogen. Hormone research, 1989, Volume: 32 Suppl 1 Topics: Animals; Breast Neoplasms; Cell Line; Estradiol; Estrogen Antagonists; Female; Humans; Polyunsaturated Alkamides; Rats; Receptors, Estrogen; Tamoxifen; Uterus	1989
[Biological action of the antiestrogen ICI 164.384 in the MCF-7 mammary cancer cell line]. Pathologie-biologie, 1989, Volume: 37, Issue:7 Topics: Breast Neoplasms; Cell Division; DNA; Estradiol; Estrogen Antagonists; Estrone; Humans; Polyunsaturated Alkamides; Receptors, Progesterone; Tumor Cells, Cultured	1989
Effects of antioestrogens on the proliferation of MCF-7 human breast cancer cells. Journal of molecular endocrinology, 1989, Volume: 2, Issue:3 Topics: Breast Neoplasms; Cell Division; Depression, Chemical; Drug Interactions; Estradiol; Estrogen Antagonists; Female; Humans; Insulin; Insulin-Like Growth Factor I; Polyunsaturated Alkamides; Tamoxifen; Transforming Growth Factors; Tumor Cells, Cultured	1989
Comparative studies on the effects of steroidal and nonsteroidal oestrogen antagonists on the proliferation of human breast cancer cells. Journal of steroid biochemistry, 1989, Volume: 34, Issue:1-6 Topics: Breast Neoplasms; Cell Division; Cell Line; Estradiol; Estrogen Antagonists; Female; Humans; Insulin; Kinetics; Polyunsaturated Alkamides; Structure-Activity Relationship; Tamoxifen; Tumor Cells, Cultured	1989
Points of action of estrogen antagonists and a calmodulin antagonist within the MCF-7 human breast cancer cell cycle. Cancer research, 1989, May-01, Volume: 49, Issue:9 Topics: Breast Neoplasms; Calmodulin; Cell Cycle; Clomiphene; DNA; Estradiol; Estrogen Antagonists; Female; Humans; Imidazoles; Polyunsaturated Alkamides; Tumor Cells, Cultured	1989
Inhibition of tamoxifen-stimulated growth of an MCF-7 tumor variant in athymic mice by novel steroidal antiestrogens. Cancer research, 1989, Aug-01, Volume: 49, Issue:15 Topics: Animals; Breast Neoplasms; Cell Division; Estradiol; Estrogen Antagonists; Female; Humans; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Polyunsaturated Alkamides; Tamoxifen; Transplantation, Heterologous	1989
Effects of the antioestrogen, ICI 164,384, on oestrogen induced RNAs in MCF-7 cells. Journal of steroid biochemistry, 1989, Volume: 33, Issue:1 Topics: Breast Neoplasms; Cell Line; Estradiol; Estrogen Antagonists; Female; Humans; Kinetics; Neoplasm Proteins; Polyunsaturated Alkamides; RNA, Neoplasm	1989
Contrasting ability of antiestrogens to inhibit MCF-7 growth stimulated by estradiol or epidermal growth factor. European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:1 Topics: Breast Neoplasms; Cell Line; DNA, Neoplasm; Dose-Response Relationship, Drug; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Female; Humans; Mitosis; Polyunsaturated Alkamides; Tamoxifen; Time Factors	1989
[Cancer of the breast, mechanism of action of anti-estrogens]. Pathologie-biologie, 1988, Volume: 36, Issue:8 Topics: Breast Neoplasms; Cell Line, Transformed; Estradiol; Estrone; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Tamoxifen	1988