Page last updated: 2024-08-24

ibutilide and Torsade de Pointes

ibutilide has been researched along with Torsade de Pointes in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.76)18.2507
2000's14 (66.67)29.6817
2010's6 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS1
Le, DD; Levis, JT; Lugovskaya, N; Vinson, DR1
Havakuk, O; Viskin, S1
Reiffel, JA1
Antonatos, D; Babalis, D; Christou, A; Kafkas, N; Katsanos, S; Nikolaou, N; Patsilinakos, S; Spanodimos, S1
Antoons, G; Beekman, JD; Boulaksil, M; de Bakker, JM; de Boer, TP; Houtman, MJ; Jungschleger, JG; Maessen, JG; van der Heyden, MA; van der Hulst, FF; van Rijen, HV; van Veen, TA; Vos, MA; Wilders, R1
Crijns, HJ; Vos, MA1
Caron, MF; Coleman, CI; Kalus, JS; Kluger, J; White, CM1
Paulussen, AD; Vos, MA1
Gowda, RM; Khan, IA; Punukollu, G; Sacchi, TJ; Vasavada, BC; Wilbur, SL1
Brendorp, B; Elming, H; Køber, L; Pedersen, OD; Pehrson, S; Torp-Petersen, C1
Kluger, J; Shah, SA; White, CM1
Brunden, MN; Buchanan, LV; Gibson, JK; Kabell, G1
Chang, MS; Chen, SA; Chen, YJ; Ding, YA; Hsieh, MH; Lee, SH1
Chow, MS; Dunn, AB; Kluger, J; Reddy, P; White, CM1
Abrahamsson, C; Amos, GJ; Carlsson, L; Duker, G; Hondeghem, L; Palmer, M1
Chatterjee, K; Cheng, J; Glatter, K; Kayser, S; Modin, G; Scheinman, MM; Yang, Y1
Kilborn, MJ; Liu, XK; Pezzullo, JC; Rodriguez, I; Woosley, RL1
Carlsson, L; Johansson, M1
Amlie, JP; Harg, P; Madsen, S1

Reviews

5 review(s) available for ibutilide and Torsade de Pointes

ArticleYear
Myocardial repolarization and drugs. Impossibility to predict the dominance of anti-arrhythmic over pro-arrhythmic effects of drugs due to differential and ventricular electrical remodeling.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2001, Volume: 1, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Disease Models, Animal; Humans; Phenethylamines; Sulfonamides; Tachycardia, Ventricular; Torsades de Pointes

2001
Genetic basis of drug-induced arrhythmias.
    Annals of medicine, 2004, Volume: 36 Suppl 1

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cytochrome P-450 Enzyme System; Dogs; Electrocardiography; Long QT Syndrome; Mutation; Sulfonamides; Torsades de Pointes

2004
Female preponderance in ibutilide-induced torsade de pointes.
    International journal of cardiology, 2004, Volume: 95, Issue:2-3

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Incidence; Male; Sex Distribution; Sulfonamides; Torsades de Pointes

2004
A benefit-risk assessment of class III antiarrhythmic agents.
    Expert opinion on drug safety, 2004, Volume: 3, Issue:6

    Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Combined Modality Therapy; Defibrillators, Implantable; Dronedarone; Heart Conduction System; Humans; Hydantoins; Imidazolidines; Ion Transport; Life Tables; Membrane Potentials; Meta-Analysis as Topic; Phenethylamines; Piperazines; Risk Assessment; Sotalol; Sulfonamides; Survival Analysis; Torsades de Pointes; Treatment Outcome

2004
Monotherapy versus combination therapy with class III antiarrhythmic agents to attenuate transmural dispersion of repolarization: a potential risk factor for torsade de pointes.
    Pharmacotherapy, 2007, Volume: 27, Issue:9

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Drug Therapy, Combination; Electrocardiography; Electrophysiologic Techniques, Cardiac; Heart Conduction System; Humans; Sotalol; Sulfonamides; Torsades de Pointes

2007

Trials

2 trial(s) available for ibutilide and Torsade de Pointes

ArticleYear
Effect of high doses of magnesium on converting ibutilide to a safe and more effective agent.
    The American journal of cardiology, 2010, Sep-01, Volume: 106, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cohort Studies; Drug Therapy, Combination; Female; Humans; Magnesium Sulfate; Male; Middle Aged; Sulfonamides; Torsades de Pointes; Treatment Outcome

2010
Model of effect of magnesium prophylaxis on frequency of torsades de pointes in ibutilide-treated patients.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2004, Apr-01, Volume: 61, Issue:7

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Female; Humans; Magnesium; Male; Middle Aged; Monte Carlo Method; Sulfonamides; Torsades de Pointes; United States

2004

Other Studies

14 other study(ies) available for ibutilide and Torsade de Pointes

ArticleYear
MICE models: superior to the HERG model in predicting Torsade de Pointes.
    Scientific reports, 2013, Volume: 3

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes

2013
ECG Diagnosis: Ibutilide-induced Torsade de Pointes.
    The Permanente journal, 2019, Volume: 23

    Topics: Anti-Arrhythmia Agents; Electrocardiography; Humans; Male; Middle Aged; Sulfonamides; Torsades de Pointes

2019
Reply: Long-QT Syndrome, Brugada Syndrome, and Catecholaminergic Polymorphic Ventricular Tachycardia: A Tale of 3 Diseases : Ibutilide as a Torsade de Pointes Stress Test.
    Journal of the American College of Cardiology, 2016, 06-14, Volume: 67, Issue:23

    Topics: Brugada Syndrome; Electrocardiography; Exercise Test; Humans; Long QT Syndrome; Sulfonamides; Tachycardia, Ventricular; Torsades de Pointes

2016
Ibutilide as a Torsade de Pointes Stress Test.
    Journal of the American College of Cardiology, 2016, 06-14, Volume: 67, Issue:23

    Topics: Anti-Arrhythmia Agents; Electrocardiography; Exercise Test; Humans; Sulfonamides; Torsades de Pointes

2016
Drug-induced torsade de pointes arrhythmias in the chronic AV block dog are perpetuated by focal activity.
    Circulation. Arrhythmia and electrophysiology, 2011, Volume: 4, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Atrioventricular Block; Collagen; Connexin 43; Disease Models, Animal; Dogs; Electrophysiologic Techniques, Cardiac; Heart Ventricles; Hypertrophy; Refractory Period, Electrophysiological; Sodium Channels; Sulfonamides; Torsades de Pointes; Ventricular Dysfunction, Left; Ventricular Dysfunction, Right

2011
Ibutilide (Corvert): suspected association with torsades de pointes.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2004, Oct-12, Volume: 171, Issue:8

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Fatal Outcome; Humans; Male; Middle Aged; Sulfonamides; Torsades de Pointes

2004
Comparative assessment of ibutilide, D-sotalol, clofilium, E-4031, and UK-68,798 in a rabbit model of proarrhythmia.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Electrocardiography; Heart Conduction System; Heart Rate; Male; Methoxamine; Phenethylamines; Piperidines; Pyridines; Quaternary Ammonium Compounds; Rabbits; Software; Sotalol; Sulfonamides; Torsades de Pointes

1993
Proarrhythmic effects of ibutilide in a canine model of pacing induced cardiomyopathy.
    Pacing and clinical electrophysiology : PACE, 2000, Volume: 23, Issue:2

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Cardiomyopathies; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Heart Rate; Heart Ventricles; Hemodynamics; Male; Sulfonamides; Torsades de Pointes

2000
Efficacy and cost analysis of ibutilide.
    The Annals of pharmacotherapy, 2000, Volume: 34, Issue:11

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Costs and Cost Analysis; Electric Countershock; Female; Humans; Male; Medical Records; Sulfonamides; Torsades de Pointes

2000
Potassium and calcium current blocking properties of the novel antiarrhythmic agent H 345/52: implications for proarrhythmic potential.
    Cardiovascular research, 2001, Feb-01, Volume: 49, Issue:2

    Topics: Action Potentials; Alkanes; Animals; Anti-Arrhythmia Agents; Bridged Bicyclo Compounds; Calcium Channels, L-Type; Heart Ventricles; In Vitro Techniques; Inhibitory Concentration 50; Male; Models, Animal; Patch-Clamp Techniques; Perfusion; Potassium Channels; Propanolamines; Purkinje Fibers; Rabbits; Sulfonamides; Torsades de Pointes

2001
Chemical cardioversion of atrial fibrillation or flutter with ibutilide in patients receiving amiodarone therapy.
    Circulation, 2001, Jan-16, Volume: 103, Issue:2

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Drug Therapy, Combination; Echocardiography; Electrocardiography; Female; Heart Rate; Humans; Male; Middle Aged; Stroke Volume; Sulfonamides; Torsades de Pointes

2001
Drug-induced QT prolongation in women during the menstrual cycle.
    JAMA, 2001, Mar-14, Volume: 285, Issue:10

    Topics: Adult; Analysis of Variance; Anti-Arrhythmia Agents; Electrocardiography; Estradiol; Female; Heart Rate; Humans; Male; Menstrual Cycle; Progesterone; Risk Factors; Sex Factors; Sulfonamides; Testosterone; Torsades de Pointes

2001
Female gender does not influence the magnitude of ibutilide-induced repolarization delay and incidence of torsades de pointes in an in vivo rabbit model of the acquired long QT syndrome.
    Journal of cardiovascular pharmacology and therapeutics, 2001, Volume: 6, Issue:3

    Topics: Age Factors; Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Female; Long QT Syndrome; Male; Rabbits; Sex Characteristics; Sulfonamides; Torsades de Pointes

2001
[Severe ibutilide-induced arrhythmia in patients with heart failure].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2001, Oct-10, Volume: 121, Issue:24

    Topics: Aged; Anti-Arrhythmia Agents; Contraindications; Drug Therapy, Combination; Fatal Outcome; Heart Failure; Humans; Male; Middle Aged; Sulfonamides; Torsades de Pointes

2001