Page last updated: 2024-10-28

ibuprofen and Uremia

ibuprofen has been researched along with Uremia in 7 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research Excerpts

ExcerptRelevanceReference
"We reported that aspirin (ASA) abnormally prolongs bleeding time (BT) in uremia."7.67Aspirin prolongs bleeding time in uremia by a mechanism distinct from platelet cyclooxygenase inhibition. ( Bonati, M; Gaspari, F; Livio, M; Orisio, S; Remuzzi, G; Viganò, G, 1987)
"We reported that aspirin (ASA) abnormally prolongs bleeding time (BT) in uremia."3.67Aspirin prolongs bleeding time in uremia by a mechanism distinct from platelet cyclooxygenase inhibition. ( Bonati, M; Gaspari, F; Livio, M; Orisio, S; Remuzzi, G; Viganò, G, 1987)
"Ibuprofen (400 mg) was orally administered to each patient 1 hr or 4 hr prior to hemodialysis."1.27Absorption and disposition of ibuprofen in hemodialyzed uremic patients. ( Au, DS; Krothapalli, R; Kuo, TH; Lee, CS; Senekjian, HO, 1983)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
van Ham, WB1
Cornelissen, CM1
van Veen, TAB1
Pearce, GA1
Brown, KF1
Senekjian, HO1
Lee, CS1
Kuo, TH1
Au, DS1
Krothapalli, R1
Dasgupta, A2
Volk, A1
Timmerman, TG1
Príborský, J1
Takayama, K1
Nagai, T1
Gaspari, F1
Viganò, G1
Orisio, S1
Bonati, M1
Livio, M1
Remuzzi, G1

Reviews

1 review available for ibuprofen and Uremia

ArticleYear
Uremic toxins in chronic kidney disease highlight a fundamental gap in understanding their detrimental effects on cardiac electrophysiology and arrhythmogenesis.
    Acta physiologica (Oxford, England), 2022, Volume: 236, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Cardio-Renal Syndrome; Cardiovascular Diseases; Electrophysiologic Te

2022

Other Studies

6 other studies available for ibuprofen and Uremia

ArticleYear
Heat inhibition of in vitro lipolysis and 14C ibuprofen protein binding in plasma from heparinized uraemic subjects.
    Life sciences, 1983, Oct-10, Volume: 33, Issue:15

    Topics: Adolescent; Adult; Aged; Blood Proteins; False Positive Reactions; Fatty Acids, Nonesterified; Femal

1983
Absorption and disposition of ibuprofen in hemodialyzed uremic patients.
    European journal of rheumatology and inflammation, 1983, Volume: 6, Issue:2

    Topics: Absorption; Adult; Arteries; Half-Life; Humans; Ibuprofen; Male; Middle Aged; Renal Dialysis; Ultraf

1983
Displacement of valproic acid and carbamazepine from protein binding in normal and uremic sera by tolmetin, ibuprofen, and naproxen: presence of inhibitor in uremic serum that blocks valproic acid-naproxen interactions.
    Therapeutic drug monitoring, 1996, Volume: 18, Issue:3

    Topics: Binding, Competitive; Blood Proteins; Carbamazepine; Cyclooxygenase Inhibitors; Drug Interactions; H

1996
In vitro displacement of phenytoin from protein binding by nonsteroidal antiinflammatory drugs tolmetin, ibuprofen, and naproxen in normal and uremic sera.
    Therapeutic drug monitoring, 1996, Volume: 18, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Humans; Ibuprofen; Naproxen; Phenytoin; Pro

1996
Influence of acute uraemia on percutaneous absorption of nonsteroidal anti-inflammatory drugs.
    Acta Universitatis Palackianae Olomucensis Facultatis Medicae, 1998, Volume: 141

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Indomethacin

1998
Aspirin prolongs bleeding time in uremia by a mechanism distinct from platelet cyclooxygenase inhibition.
    The Journal of clinical investigation, 1987, Volume: 79, Issue:6

    Topics: Acetylation; Adult; Aged; Aspirin; Bleeding Time; Blood Platelets; Cyclooxygenase Inhibitors; Female

1987