Page last updated: 2024-10-28

ibuprofen and Thrombopenia

ibuprofen has been researched along with Thrombopenia in 11 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Research Excerpts

ExcerptRelevanceReference
"Hemodynamically significant patent ductus arteriosus (hsPDA) in very low birth weight (VLBW) infants is routinely treated in many countries with oral ibuprofen."8.02Oral ibuprofen promoted cholestatic liver disease in very low birth weight infants with patent ductus arteriosus. ( Guo, H; Huang, Y; Lin, HC; Liu, H; Peng, H; Shen, X; Yao, S; Zhou, M; Zhou, P, 2021)
"A 54-year-old woman with a 19-year history of rheumatoid arthritis developed life-threatening thrombocytopenia one week after beginning butoconazole therapy for a vaginal yeast infection."7.68Severe reversible thrombocytopenia resulting from butoconazole cream. ( Campbell, JR; Maloley, PA; Montgomery, HA; Nelson, E, 1990)
"Hemodynamically significant patent ductus arteriosus (hsPDA) in very low birth weight (VLBW) infants is routinely treated in many countries with oral ibuprofen."4.02Oral ibuprofen promoted cholestatic liver disease in very low birth weight infants with patent ductus arteriosus. ( Guo, H; Huang, Y; Lin, HC; Liu, H; Peng, H; Shen, X; Yao, S; Zhou, M; Zhou, P, 2021)
"A 54-year-old woman with a 19-year history of rheumatoid arthritis developed life-threatening thrombocytopenia one week after beginning butoconazole therapy for a vaginal yeast infection."3.68Severe reversible thrombocytopenia resulting from butoconazole cream. ( Campbell, JR; Maloley, PA; Montgomery, HA; Nelson, E, 1990)
"The occurrence of patent ductus arteriosus was less frequent only on day 3 of life in the ibuprofen group."2.71Prophylactic ibuprofen for the prevention of intraventricular hemorrhage among preterm infants: a multicenter, randomized study. ( Bertini, G; Dani, C; Guerrini, P; Martano, C; Pezzati, M; Poggi, C; Rubaltelli, FF, 2005)
" Data suggesting that conditions associated with chronic liver damage reduce the dosing threshold for induction of liver failure are of particular concern."2.61Symptomatic treatment of dengue: should the NSAID contraindication be reconsidered? ( Fernandes, L; Kellstein, D, 2019)
"The patient developed coma, metabolic acidosis, and mild thrombocytopenia, but improved rapidly with supportive care."1.31Massive ibuprofen ingestion with survival. ( Bronstein, AC; McGuire, T; Seifert, SA, 2000)
" An overestimation of rare side-effects of drugs should not block the application of certain medicaments, however, they should be given only in such a high dosage as it is necessary."1.26[Hematotoxic lesions caused by non-steroidal antirheumatic agents]. ( Hüge, W; Stobbe, H, 1980)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's1 (9.09)18.2507
2000's2 (18.18)29.6817
2010's4 (36.36)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Shen, X1
Huang, Y1
Guo, H1
Peng, H1
Yao, S1
Zhou, M1
Liu, H1
Lin, HC1
Zhou, P1
Toom, S1
Wolf, B1
Avula, A1
Peeke, S1
Becker, K1
Kellstein, D1
Fernandes, L1
Tofé Valera, I1
Jaraba Caballero, MP1
Ruiz González, MD1
Rodríguez Benítez, MV1
Parraga Quiles, MJ1
Sallmon, H1
Weber, SC1
Hüning, B1
Stein, A1
Horn, PA1
Metze, BC1
Dame, C1
Bührer, C1
Felderhoff-Müser, U1
Hansmann, G1
Koehne, P1
Dani, C2
Poggi, C2
Fontanelli, G1
Bertini, G1
Pezzati, M1
Guerrini, P1
Martano, C1
Rubaltelli, FF1
de la Coussaye, JE1
Mourad, G1
Canaud, B1
Chong, G1
Beraud, JJ1
Mion, C1
Stobbe, H1
Hüge, W1
Seifert, SA1
Bronstein, AC1
McGuire, T1
Maloley, PA1
Nelson, E1
Montgomery, HA1
Campbell, JR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Liberal Versus Restrictive Platelet Transfusion for Treatment of Hemodynamically Significant Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates- A Randomized Open Label, Controlled Trial[NCT03022253]Phase 344 participants (Anticipated)Interventional2016-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for ibuprofen and Thrombopenia

ArticleYear
Symptomatic treatment of dengue: should the NSAID contraindication be reconsidered?
    Postgraduate medicine, 2019, Volume: 131, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Contraindications, Drug; Dengue; Fever; Hemorrhage; Humans;

2019

Trials

1 trial available for ibuprofen and Thrombopenia

ArticleYear
Prophylactic ibuprofen for the prevention of intraventricular hemorrhage among preterm infants: a multicenter, randomized study.
    Pediatrics, 2005, Volume: 115, Issue:6

    Topics: Cerebral Hemorrhage; Cerebral Ventricles; Cerebrovascular Circulation; Double-Blind Method; Ductus A

2005

Other Studies

9 other studies available for ibuprofen and Thrombopenia

ArticleYear
Oral ibuprofen promoted cholestatic liver disease in very low birth weight infants with patent ductus arteriosus.
    Clinics and research in hepatology and gastroenterology, 2021, Volume: 45, Issue:2

    Topics: Birth Weight; Cholestasis; Ductus Arteriosus, Patent; Emulsions; Humans; Ibuprofen; Indomethacin; In

2021
Familial thrombocytopenia flare-up following the first dose of mRNA-1273 Covid-19 vaccine.
    American journal of hematology, 2021, 05-01, Volume: 96, Issue:5

    Topics: 2019-nCoV Vaccine mRNA-1273; Adult; Analgesics, Non-Narcotic; Chronic Disease; COVID-19; COVID-19 Va

2021
The Role of Paracetamol for Closing Patent Ductus Arteriosus. A Challenging Alternative for Ductal Closure?
    Revista espanola de cardiologia (English ed.), 2016, Volume: 69, Issue:11

    Topics: Acetaminophen; Administration, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Cerebral Hemorr

2016
Thrombocytopenia in the first 24 hours after birth and incidence of patent ductus arteriosus.
    Pediatrics, 2012, Volume: 130, Issue:3

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Echocardiography, Doppler; Female; Humans; Ibu

2012
Relationship between platelet count and volume and spontaneous and pharmacological closure of ductus arteriosus in preterm infants.
    American journal of perinatology, 2013, Volume: 30, Issue:5

    Topics: Blood Platelets; Cell Size; Cohort Studies; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Fe

2013
[Acute renal insufficiency and recurrent thrombopenia caused by crossed intolerance to ibuprofen and fenoprofen].
    Presse medicale (Paris, France : 1983), 1983, Nov-26, Volume: 12, Issue:43

    Topics: Acute Kidney Injury; Aged; Fenoprofen; Humans; Ibuprofen; Male; Phenylpropionates; Recurrence; Throm

1983
[Hematotoxic lesions caused by non-steroidal antirheumatic agents].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1980, Dec-01, Volume: 35, Issue:23

    Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Aspirin; Diclofenac; Female;

1980
Massive ibuprofen ingestion with survival.
    Journal of toxicology. Clinical toxicology, 2000, Volume: 38, Issue:1

    Topics: Acidosis; Adolescent; Analgesics, Non-Narcotic; Coma; Drug Overdose; Female; Humans; Ibuprofen; Thro

2000
Severe reversible thrombocytopenia resulting from butoconazole cream.
    DICP : the annals of pharmacotherapy, 1990, Volume: 24, Issue:2

    Topics: Administration, Intravaginal; Antifungal Agents; Female; Humans; Ibuprofen; Imidazoles; Methotrexate

1990