Page last updated: 2024-10-28

ibuprofen and Sinusitis

ibuprofen has been researched along with Sinusitis in 4 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Sinusitis: Inflammation of the NASAL MUCOSA in one or more of the PARANASAL SINUSES.

Research Excerpts

ExcerptRelevanceReference
" We sought to evaluate the effectiveness and safety of over the counter dosing of ibuprofen on pain and bleeding rates following ESS."5.56Effect of Over the Counter Ibuprofen Dosing after Sinus Surgery for Chronic Rhinosinusitis: A Prospective Cohort Pilot Study. ( Davis, GE; Humphreys, IM; Miller, C, 2020)
" We sought to evaluate the effectiveness and safety of over the counter dosing of ibuprofen on pain and bleeding rates following ESS."1.56Effect of Over the Counter Ibuprofen Dosing after Sinus Surgery for Chronic Rhinosinusitis: A Prospective Cohort Pilot Study. ( Davis, GE; Humphreys, IM; Miller, C, 2020)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Miller, C1
Humphreys, IM1
Davis, GE1
Ayoub, NF1
Choby, G1
Turner, JH1
Abuzeid, WM1
Raviv, JR1
Thamboo, A1
Ma, Y1
Chandra, RK1
Chowdhury, NI1
Stokken, JK1
O'Brien, EK1
Shah, S1
Akbar, N1
Roozdar, P1
Nayak, JV1
Patel, ZM1
Hwang, PH1
Sacco, KA1
Pongdee, T1
Rosado, A1
Vives, R1
González, R1
RodrĂ­guez, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multi-institutional, Randomized Controlled Trial Assessing Opioid Use and Analgesic Requirements After Endoscopic Sinus Surgery[NCT03783702]Phase 4118 participants (Actual)Interventional2019-04-04Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Brief Pain Inventory (BPI) Score

"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 1

Interventionunits on a scale (Mean)
Experimental Group2.8
Control Group2.9

Brief Pain Inventory (BPI) Score

"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 2

Interventionunits on a scale (Mean)
Experimental Group2.5
Control Group2.3

Brief Pain Inventory (BPI) Score

"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 3

Interventionunits on a scale (Mean)
Experimental Group1.9
Control Group2.1

Brief Pain Inventory (BPI) Score

"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 4

Interventionunits on a scale (Mean)
Experimental Group1.5
Control Group1.9

Brief Pain Inventory (BPI) Score

"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 5

Interventionunits on a scale (Mean)
Experimental Group1.7
Control Group1.6

Brief Pain Inventory (BPI) Score

"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 6

Interventionunits on a scale (Mean)
Experimental Group1.5
Control Group1.4

Brief Pain Inventory (BPI) Score

"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 7

Interventionunits on a scale (Mean)
Experimental Group1.3
Control Group1.4

Brief Pain Inventory (BPI) Score

"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: BPI score will be collected at the preoperative visit

Interventionunits on a scale (Mean)
Experimental Group1.6
Control Group1.0

Pain Severity

"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score was collected for postoperative day 1

Interventionunits on a scale (Mean)
Experimental Group30.2
Control Group29.4

Pain Severity

"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 2

Interventionunits on a scale (Mean)
Experimental Group27.0
Control Group23.5

Pain Severity

"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 3

Interventionunits on a scale (Mean)
Experimental Group19.2
Control Group22.5

Pain Severity

"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 4

Interventionunits on a scale (Mean)
Experimental Group14.1
Control Group16.8

Pain Severity

"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 5

Interventionunits on a scale (Mean)
Experimental Group15.8
Control Group15.0

Pain Severity

"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 6

Interventionunits on a scale (Mean)
Experimental Group13.9
Control Group11.7

Pain Severity

"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 7

Interventionunits on a scale (Mean)
Experimental Group8.1
Control Group10.1

Pain Severity

"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for preoperative visit (the day before surgery)

Interventionunits on a scale (Mean)
Experimental Group12.4
Control Group8.5

Severity of Epistaxis

"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected at the preoperative visit

Interventionunits on a scale (Mean)
Experimental Group0
Control Group0

Severity of Epistaxis

"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 1

Interventionunits on a scale (Mean)
Experimental Group36.3
Control Group38.9

Severity of Epistaxis

"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 2

Interventionunits on a scale (Mean)
Experimental Group23.0
Control Group21.6

Severity of Epistaxis

"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 3

Interventionunits on a scale (Mean)
Experimental Group15.9
Control Group12.9

Severity of Epistaxis

"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 4

Interventionunits on a scale (Mean)
Experimental Group9.3
Control Group11.8

Severity of Epistaxis

"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 5

Interventionunits on a scale (Mean)
Experimental Group10.1
Control Group7.8

Severity of Epistaxis

"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 6

Interventionunits on a scale (Mean)
Experimental Group6.5
Control Group6.6

Severity of Epistaxis

"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 7

Interventionunits on a scale (Mean)
Experimental Group4.6
Control Group5.4

Medication Log

Patients kept a daily medication log and reported the number of doses consumed per day (650mg acetaminophen, 600mg ibuprofen, 5mg oxycodone). The mean number of medication doses per day was calculated for each treatment group. (NCT03783702)
Timeframe: Postoperative day 1 to 7

,
InterventionAverage number of medication doses/day (Mean)
Oxycodone POD1Oxycodone POD2Oxycodone POD3Oxycodone POD4Oxycodone POD5Oxycodone POD6Oxycodone POD7Acetaminophen POD1Acetaminophen POD2Acetaminophen POD3Acetaminophen POD4Acetaminophen POD5Acetaminophen POD6Acetaminophen POD7Ibuprofen POD1Ibuprofen POD2Ibuprofen POD3Ibuprofen POD4Ibuprofen POD5Ibuprofen POD6Ibuprofen POD7
Control Group0.60.40.30.30.30.102.11.91.61.51.31.10.60000000
Experimental Group0.30.10.10.10.10.102.01.81.31.00.90.90.60.60.50.40.30.40.30.2

Trials

1 trial available for ibuprofen and Sinusitis

ArticleYear
Assessment of Opioid Use and Analgesic Requirements After Endoscopic Sinus Surgery: A Randomized Clinical Trial.
    JAMA otolaryngology-- head & neck surgery, 2021, 09-01, Volume: 147, Issue:9

    Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi

2021

Other Studies

3 other studies available for ibuprofen and Sinusitis

ArticleYear
Effect of Over the Counter Ibuprofen Dosing after Sinus Surgery for Chronic Rhinosinusitis: A Prospective Cohort Pilot Study.
    The Annals of otology, rhinology, and laryngology, 2020, Volume: 129, Issue:7

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Chronic Disease; Cohort St

2020
52-Year-Old Man With Hyposmia, Rhinorrhea, and Wheezing.
    Mayo Clinic proceedings, 2018, Volume: 93, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Asthma, Aspirin-Induced; Humans; Ibuprofen; Male; Middle Ag

2018
Can NSAIDs intolerance disappear? A study of three cases.
    Allergy, 2003, Volume: 58, Issue:7

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Drug Hypersensitivity; Forced Expir

2003