ibuprofen has been researched along with Shock in 10 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the ibuprofen group, but not the placebo group, there were significant declines in urinary levels of prostacyclin and thromboxane, temperature, heart rate, oxygen consumption, and lactic acidosis." | 9.08 | The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group. ( Bernard, GR; Christman, BW; Dupont, WD; Fulkerson, WJ; Higgins, SB; Russell, JA; Schein, R; Steinberg, KP; Summer, WR; Swindell, BB; Wheeler, AP; Wright, PE, 1997) |
| "To report a child who developed shock, loss of consciousness, and metabolic acidosis following an ibuprofen overdose." | 7.69 | Shock, metabolic acidosis, and coma following ibuprofen overdose in a child. ( Uy, CC; Zuckerman, GB, 1995) |
| "This study was done to evaluate the role of ibuprofen, a cyclooxygenase inhibitor, in a standard model of hypovolemic shock." | 7.67 | Hemodynamic evaluation of ibuprofen in canine hypovolemic shock. ( Beamer, KC; Daly, T; Vargish, T, 1987) |
| "In the ibuprofen group, but not the placebo group, there were significant declines in urinary levels of prostacyclin and thromboxane, temperature, heart rate, oxygen consumption, and lactic acidosis." | 5.08 | The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group. ( Bernard, GR; Christman, BW; Dupont, WD; Fulkerson, WJ; Higgins, SB; Russell, JA; Schein, R; Steinberg, KP; Summer, WR; Swindell, BB; Wheeler, AP; Wright, PE, 1997) |
| "To report a child who developed shock, loss of consciousness, and metabolic acidosis following an ibuprofen overdose." | 3.69 | Shock, metabolic acidosis, and coma following ibuprofen overdose in a child. ( Uy, CC; Zuckerman, GB, 1995) |
| "This study was done to evaluate the role of ibuprofen, a cyclooxygenase inhibitor, in a standard model of hypovolemic shock." | 3.67 | Hemodynamic evaluation of ibuprofen in canine hypovolemic shock. ( Beamer, KC; Daly, T; Vargish, T, 1987) |
| "Ibuprofen is a potent cyclooxygenase inhibitor known to reduce the production of arachidonic acid metabolites." | 2.38 | Ibuprofen in acute-care therapy. ( Ehrlich, HP; Rockwell, WB, 1990) |
| "All rabbits were subjected to stepwise cardiac tamponade by inflation of a handmade balloon placed into the pericardial sac to reduce DO2." | 1.32 | Effect of Ibuprofen on interleukin-1beta-induced abnormalities in hemodynamics and oxygen metabolism in rabbits. ( Irisawa, T; Kuwagata, Y; Matsuyama, S; Nakamori, Y; Oda, J; Sugimoto, H; Takahashi, M, 2003) |
| "Pretreatment with ibuprofen prevented the hemodynamic, leukocyte, and platelet changes induced by the low-dose cytokine combination, and ameliorated the pulmonary tissue damage." | 1.27 | Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition. ( Connolly, RJ; Dinarello, CA; Gelfand, JA; Ikejima, T; Okusawa, S, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Geith, S | 1 |
| Renner, B | 1 |
| Rabe, C | 1 |
| Stenzel, J | 1 |
| Eyer, F | 1 |
| Akingbola, OA | 1 |
| Singh, D | 1 |
| Kleinman, JA | 1 |
| Frieberg, EM | 1 |
| Kuwagata, Y | 1 |
| Oda, J | 1 |
| Irisawa, T | 1 |
| Matsuyama, S | 1 |
| Nakamori, Y | 1 |
| Takahashi, M | 1 |
| Sugimoto, H | 1 |
| Jennes, S | 1 |
| Saidane, G | 1 |
| Fauville, JP | 1 |
| Ledoux, M | 1 |
| Colinet, B | 1 |
| Zuckerman, GB | 1 |
| Uy, CC | 1 |
| Bernard, GR | 1 |
| Wheeler, AP | 1 |
| Russell, JA | 1 |
| Schein, R | 1 |
| Summer, WR | 1 |
| Steinberg, KP | 1 |
| Fulkerson, WJ | 1 |
| Wright, PE | 1 |
| Christman, BW | 1 |
| Dupont, WD | 1 |
| Higgins, SB | 1 |
| Swindell, BB | 1 |
| Rockwell, WB | 1 |
| Ehrlich, HP | 1 |
| Okusawa, S | 1 |
| Gelfand, JA | 1 |
| Ikejima, T | 1 |
| Connolly, RJ | 1 |
| Dinarello, CA | 1 |
| Bertini, R | 1 |
| Bianchi, M | 1 |
| Ghezzi, P | 1 |
| Beamer, KC | 1 |
| Daly, T | 1 |
| Vargish, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000574] | Phase 3 | 0 participants | Interventional | 1990-09-30 | Completed | ||
| A Phase II Double Blind Randomized Controlled Trial of High Dose Vitamin B12 in Septic Shock[NCT03783091] | Phase 2 | 20 participants (Anticipated) | Interventional | 2019-08-05 | Recruiting | ||
| Control of Fever in Septic Patients[NCT04227652] | 140 participants (Actual) | Interventional | 2013-09-03 | Completed | |||
| Comparison of the Efficacy of Paracetamol and Ibuprofen in the Management of Fever in Sepsis Patients: A Randomized Double-Blind Controlled Study[NCT06061575] | Phase 4 | 84 participants (Anticipated) | Interventional | 2023-10-31 | Not yet recruiting | ||
| Phase 2 Single Center, Randomized, Placebo-controlled, Double-blind, Parallel Group Study to Evaluate Efficacy of Para-Tyrosine Supplementation on the Survival and Clinical Outcome in Patients With Sepsis[NCT03278730] | Phase 2 | 296 participants (Anticipated) | Interventional | 2025-02-28 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ibuprofen and Shock
| Article | Year |
|---|---|
Ibuprofen in acute-care therapy.
Topics: Acute Disease; Animals; Cardiomyopathies; Humans; Ibuprofen; Immunity; Lung; Shock; Shock, Septic; W | 1990 |
1 trial available for ibuprofen and Shock
| Article | Year |
|---|---|
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
8 other studies available for ibuprofen and Shock
| Article | Year |
|---|---|
Ibuprofen plasma concentration profile in deliberate ibuprofen overdose with circulatory depression treated with therapeutic plasma exchange: a case report.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Overdose; Humans; Ibuprofen; Male; Middle Aged; Plasma | 2017 |
Functional adrenal insufficiency complicating an overdose of naproxen and ibuprofen.
Topics: Acidosis; Adolescent; Adrenal Insufficiency; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non | 2015 |
Effect of Ibuprofen on interleukin-1beta-induced abnormalities in hemodynamics and oxygen metabolism in rabbits.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Gas Analysis; | 2003 |
Transient selective factor X deficiency in a severely burned child.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Body Surface Area; Burns; Erythrocyt | 2008 |
Shock, metabolic acidosis, and coma following ibuprofen overdose in a child.
Topics: Acidosis; Child; Coma; Critical Care; Drug Overdose; Humans; Ibuprofen; Male; Shock | 1995 |
Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition.
Topics: Animals; Blood Pressure; Drug Synergism; Hemodynamics; Ibuprofen; Interleukin-1; Leukocyte Count; Lu | 1988 |
Adrenalectomy sensitizes mice to the lethal effects of interleukin 1 and tumor necrosis factor.
Topics: Adrenal Cortex; Adrenalectomy; Animals; Dexamethasone; Ibuprofen; Interleukin-1; Lipopolysaccharides | 1988 |
Hemodynamic evaluation of ibuprofen in canine hypovolemic shock.
Topics: Animals; Blood Pressure; Dogs; Hemodynamics; Ibuprofen; Shock; Vascular Resistance | 1987 |