ibuprofen has been researched along with Retinopathy of Prematurity in 3 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Retinopathy of Prematurity: A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether prophylactic caffeine and ibuprofen, which have been shown to have vascular endothelial growth factor-modulating properties in other contexts, have a detectable effect on the incidence of severe retinopathy of prematurity (ROP) when administered in extremely low birth weight infants during the first 48 hours of life." | 8.02 | The effect of ibuprofen and caffeine prophylaxis on retinopathy of prematurity. ( Bhatt-Mehta, V; Schumacher, RE, 2021) |
| "To determine whether prophylactic caffeine and ibuprofen, which have been shown to have vascular endothelial growth factor-modulating properties in other contexts, have a detectable effect on the incidence of severe retinopathy of prematurity (ROP) when administered in extremely low birth weight infants during the first 48 hours of life." | 4.02 | The effect of ibuprofen and caffeine prophylaxis on retinopathy of prematurity. ( Bhatt-Mehta, V; Schumacher, RE, 2021) |
| "Animals that received ibuprofen during hyperoxia exposure had a significantly lower median (25th, 75th quartile) retinopathy score of 6 (5, 7." | 3.72 | Ibuprofen improves oxygen-induced retinopathy in a mouse model. ( Barr, SM; Geng, Y; Higgins, RD; Sharma, J; Yun, Y, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bhatt-Mehta, V | 1 |
| Schumacher, RE | 1 |
| Yokoi, T | 2 |
| Hiraoka, M | 1 |
| Miyamoto, M | 1 |
| Kobayashi, Y | 1 |
| Nishina, S | 1 |
| Azuma, N | 1 |
| Sharma, J | 1 |
| Barr, SM | 1 |
| Geng, Y | 1 |
| Yun, Y | 1 |
| Higgins, RD | 1 |
3 other studies available for ibuprofen and Retinopathy of Prematurity
| Article | Year |
|---|---|
The effect of ibuprofen and caffeine prophylaxis on retinopathy of prematurity.
Topics: Birth Weight; Caffeine; Gestational Age; Humans; Ibuprofen; Infant, Newborn; Infant, Very Low Birth | 2021 |
Vascular abnormalities in aggressive posterior retinopathy of prematurity detected by fluorescein angiography.
Topics: Capillary Permeability; Ductus Arteriosus, Patent; Female; Fluorescein Angiography; Gestational Age; | 2009 |
Ibuprofen improves oxygen-induced retinopathy in a mouse model.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Dextrans; Disease Models, Animal | 2003 |