ibuprofen has been researched along with Respiratory Distress Syndrome in 27 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Respiratory Distress Syndrome: A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the ibuprofen group, but not the placebo group, there were significant declines in urinary levels of prostacyclin and thromboxane, temperature, heart rate, oxygen consumption, and lactic acidosis." | 9.08 | The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group. ( Bernard, GR; Christman, BW; Dupont, WD; Fulkerson, WJ; Higgins, SB; Russell, JA; Schein, R; Steinberg, KP; Summer, WR; Swindell, BB; Wheeler, AP; Wright, PE, 1997) |
| "In the ibuprofen group, but not the placebo group, there were significant declines in urinary levels of prostacyclin and thromboxane, temperature, heart rate, oxygen consumption, and lactic acidosis." | 5.08 | The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group. ( Bernard, GR; Christman, BW; Dupont, WD; Fulkerson, WJ; Higgins, SB; Russell, JA; Schein, R; Steinberg, KP; Summer, WR; Swindell, BB; Wheeler, AP; Wright, PE, 1997) |
| " ARDS was likely induced by ibuprofen, based on the presence of pancytopenia and a weakly positive drug lymphocyte stimulating test (DLST)." | 3.69 | Adult respiratory distress syndrome with increased serum and bronchoalveolar lavage fluid levels of squamous cell carcinoma-related antigen. ( Ashitani, J; Ihiboshi, H; Mashimoto, H; Matsukura, S; Mukae, H; Taniguchi, H, 1996) |
| "Porcine Pseudomonas adult respiratory distress syndrome (ARDS) has been shown to respond to combination therapy of 150 mg of cimetidine, 12." | 3.67 | Successful treatment of adult respiratory distress syndrome by histamine and prostaglandin blockade in a porcine Pseudomonas model. ( Blocher, CR; Sielaff, TD; Sugerman, HJ; Tatum, JL, 1987) |
| " We recently reported that combined treatment with methylprednisolone, ibuprofen and naloxone significantly increased lasting survival in an LD100 canine endotoxin shock model." | 3.67 | Pulmonary platelet trapping in Escherichia coli endotoxin-injected dogs treated with methylprednisolone, ibuprofen and naloxone. ( Ekström, BF; Kuenzig, M; Schwartz, SI, 1986) |
| "The effects of ibuprofen (I) and methylprednisolone (M) were studied in the Pseudomonas porcine model of adult respiratory distress syndrome (ARDS)." | 3.67 | Ibuprofen and methylprednisolone in a pig Pseudomonas ARDS model. ( Blocher, CR; Harvey, CF; Lee, EC; Sielaff, TD; Sugerman, HJ; Tatum, JL, 1987) |
| "Hydrochloric acid was injected into the trachea to produce acute respiratory failure in 18 anesthetized dogs." | 1.28 | [Effects of ibuprofen and OKY-046 on ventilation perfusion distribution in acute respiratory failure]. ( Wu, W, 1991) |
| "Ibuprofen pretreatment of septic animals completely blocked leakage of plasma proteins into the alveoli and attenuated neutrophil migration but did not prevent downregulation of AM O2-." | 1.28 | Sepsis-induced lung injury and the effects of ibuprofen pretreatment. Analysis of early alveolar events via repetitive bronchoalveolar lavage. ( Byrne, K; Carey, PD; Fowler, AA; Jenkins, JK; Sugerman, HJ, 1991) |
| "Ibuprofen is a cyclo-oxygenase inhibitor that is alleged to have additional direct effects on leukocyte function." | 1.27 | Effects of ibuprofen on endotoxin-induced alveolitis: biphasic dose response and dissociation between inflammation and hypoxemia. ( Pennock, B; Rinaldo, JE, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (59.26) | 18.7374 |
| 1990's | 9 (33.33) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gillis, RC | 2 |
| Daley, BJ | 2 |
| Enderson, BL | 2 |
| Karlstad, MD | 2 |
| Kestler, DP | 1 |
| Bone, RC | 1 |
| Jacobs, ER | 1 |
| Lee, RP | 1 |
| King, EG | 1 |
| Russell, AS | 1 |
| Cefalo, RC | 1 |
| Lewis, PE | 1 |
| O'Brien, WF | 1 |
| Fletcher, JR | 1 |
| Ramwell, PW | 1 |
| Le, HT | 1 |
| Bosse, GM | 1 |
| Tsai, Y | 1 |
| Ashitani, J | 1 |
| Mukae, H | 1 |
| Ihiboshi, H | 1 |
| Taniguchi, H | 1 |
| Mashimoto, H | 1 |
| Matsukura, S | 1 |
| Bernard, GR | 1 |
| Wheeler, AP | 1 |
| Russell, JA | 1 |
| Schein, R | 1 |
| Summer, WR | 1 |
| Steinberg, KP | 1 |
| Fulkerson, WJ | 1 |
| Wright, PE | 1 |
| Christman, BW | 1 |
| Dupont, WD | 1 |
| Higgins, SB | 1 |
| Swindell, BB | 1 |
| Wu, W | 1 |
| Jenkins, JK | 2 |
| Carey, PD | 4 |
| Byrne, K | 4 |
| Sugerman, HJ | 8 |
| Fowler, AA | 2 |
| Marra, SW | 1 |
| Oliver, AM | 1 |
| Sielaff, TD | 6 |
| Blocher, CR | 6 |
| Cooper, KR | 1 |
| Michna, B | 1 |
| Vasquez, A | 2 |
| Tatum, JL | 5 |
| Hirsh, JI | 1 |
| Davies, EA | 1 |
| Campbell, AJ | 1 |
| Devine, MJ | 1 |
| Steinberg, SM | 1 |
| Cloutier, CT | 1 |
| Rinaldo, JE | 2 |
| Pennock, B | 1 |
| Zhou, YG | 2 |
| Lee, CC | 1 |
| Wright, TP | 1 |
| Hirsh, PD | 1 |
| Hirsch, JI | 1 |
| Gnidec, AG | 1 |
| Sibbald, WJ | 1 |
| Cheung, H | 1 |
| Metz, CA | 1 |
| Wang, ZG | 1 |
| Zhou, BT | 1 |
| Hsu, K | 1 |
| Shen, CY | 1 |
| Wang, D | 1 |
| Kao, SJ | 1 |
| Chang, CL | 1 |
| Ho, ST | 1 |
| Ekström, BF | 1 |
| Kuenzig, M | 1 |
| Schwartz, SI | 1 |
| Harvey, CF | 1 |
| Lee, EC | 1 |
| Kellum, JM | 1 |
| Hasselstrøm, LJ | 1 |
| Eliasen, K | 1 |
| Mogensen, T | 1 |
| Andersen, JB | 1 |
| Dauber, JH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000574] | Phase 3 | 0 participants | Interventional | 1990-09-30 | Completed | ||
| A Phase II Double Blind Randomized Controlled Trial of High Dose Vitamin B12 in Septic Shock[NCT03783091] | Phase 2 | 20 participants (Anticipated) | Interventional | 2019-08-05 | Recruiting | ||
| Control of Fever in Septic Patients[NCT04227652] | 140 participants (Actual) | Interventional | 2013-09-03 | Completed | |||
| Comparison of the Efficacy of Paracetamol and Ibuprofen in the Management of Fever in Sepsis Patients: A Randomized Double-Blind Controlled Study[NCT06061575] | Phase 4 | 84 participants (Anticipated) | Interventional | 2023-10-31 | Not yet recruiting | ||
| Phase 2 Single Center, Randomized, Placebo-controlled, Double-blind, Parallel Group Study to Evaluate Efficacy of Para-Tyrosine Supplementation on the Survival and Clinical Outcome in Patients With Sepsis[NCT03278730] | Phase 2 | 296 participants (Anticipated) | Interventional | 2025-02-28 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for ibuprofen and Respiratory Distress Syndrome
| Article | Year |
|---|---|
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; | 1997 |
26 other studies available for ibuprofen and Respiratory Distress Syndrome
| Article | Year |
|---|---|
Role of downstream metabolic processing of proinflammatory fatty acids by 5-lipoxygenase in HL-60 cell apoptosis.
Topics: Apoptosis; Arachidonate 5-Lipoxygenase; Benzoquinones; Cyclooxygenase Inhibitors; DNA Fragmentation; | 2003 |
Regulation of apoptosis in eicosapentaenoic acid-treated HL-60 cells.
Topics: Apoptosis; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; | 2007 |
Research on ibuprofen for sepsis and respiratory failure.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Cardiac Output; Dogs; Hydrogen-Ion Con | 1984 |
Ibuprofen: a severe systemic reaction.
Topics: Amoxicillin; Dopamine; Female; Fever; Gingivitis; Humans; Hypotension; Ibuprofen; Middle Aged; Respi | 1983 |
The role of prostaglandins in endotoxemia: comparisons in response in the nonpregnant, maternal, and fetal models. I. Prostaglandins and the pulmonary effect of experimental endotoxemia.
Topics: Animals; Castration; Endotoxins; Escherichia coli; Female; Hypertension, Pulmonary; Ibuprofen; Indom | 1980 |
Ibuprofen overdose complicated by renal failure, adult respiratory distress syndrome, and metabolic acidosis.
Topics: Acidosis; Acute Kidney Injury; Adult; Charcoal; Citrates; Citric Acid; Drug Overdose; Humans; Ibupro | 1994 |
Adult respiratory distress syndrome with increased serum and bronchoalveolar lavage fluid levels of squamous cell carcinoma-related antigen.
Topics: Antigens, Neoplasm; Biomarkers; Bronchoalveolar Lavage Fluid; Humans; Ibuprofen; Interleukin-8; Leuk | 1996 |
[Effects of ibuprofen and OKY-046 on ventilation perfusion distribution in acute respiratory failure].
Topics: Animals; Dogs; Hydrochloric Acid; Ibuprofen; Methacrylates; Plethysmography, Impedance; Pulmonary Ci | 1991 |
Sepsis-induced lung injury and the effects of ibuprofen pretreatment. Analysis of early alveolar events via repetitive bronchoalveolar lavage.
Topics: Animals; Blood Pressure; Bronchoalveolar Lavage Fluid; Extravascular Lung Water; Female; Ibuprofen; | 1991 |
Successful treatment of adult respiratory distress syndrome with oral ibuprofen.
Topics: Administration, Oral; Aged; Female; Humans; Ibuprofen; Male; Middle Aged; Respiratory Distress Syndr | 1991 |
Ibuprofen prevents deterioration in static transpulmonary compliance and transalveolar protein flux in septic porcine acute lung injury.
Topics: Acute Disease; Animals; Blood Pressure; Bronchoalveolar Lavage Fluid; Capillary Permeability; Extrav | 1991 |
Increased survival time after delayed histamine and prostaglandin blockade in a porcine model of severe sepsis-induced lung injury.
Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Extravascular Lung Water; Hemodynam | 1990 |
Ranitidine compared to cimetidine in multiagent pharmacological treatment of porcine Pseudomonas ARDS.
Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Hemodynamics; Ibuprofen; Pseudomona | 1990 |
Ibuprofen plus prostaglandin E1 in a septic porcine model of adult respiratory distress syndrome.
Topics: Alprostadil; Animals; Disease Models, Animal; Drug Therapy, Combination; Hemodynamics; Ibuprofen; Ps | 1989 |
Effects of ibuprofen on endotoxin-induced alveolitis: biphasic dose response and dissociation between inflammation and hypoxemia.
Topics: Animals; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Ibuprofen; Neutrophils; Pre | 1986 |
[Effect of PGI2 plus ibuprofen on experimental respiratory distress syndrome induced by oleic acid].
Topics: Animals; Epoprostenol; Ibuprofen; Male; Oleic Acid; Oleic Acids; Rabbits; Respiratory Distress Syndr | 1988 |
Effects of ibuprofen on a pig Pseudomonas ARDS model.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Disease Model | 1986 |
Successful treatment of adult respiratory distress syndrome by histamine and prostaglandin blockade in a porcine Pseudomonas model.
Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Hemodynamics; Ibuprofen; Ketanserin | 1987 |
Ibuprofen reduces the progression of permeability edema in an animal model of hyperdynamic sepsis.
Topics: Animals; Bacterial Infections; Disease Models, Animal; Hemodynamics; Hypertension, Pulmonary; Ibupro | 1988 |
[Protective effect of PGI2 on experimental ARDS and factors influencing it].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Epoprostenol; Ibuprofen; Male; Oleic Acids; Rabbits; Respirat | 1987 |
[The protective effect of ibuprofen on an experimental model of adult respiratory distress syndrome].
Topics: Animals; Blood Gas Analysis; Capillary Permeability; Disease Models, Animal; Dogs; Female; Ibuprofen | 1986 |
Pulmonary platelet trapping in Escherichia coli endotoxin-injected dogs treated with methylprednisolone, ibuprofen and naloxone.
Topics: Animals; Blood Platelets; Blood Pressure; Diarrhea; Dogs; Endotoxins; Escherichia coli; Female; Hema | 1986 |
Ibuprofen and methylprednisolone in a pig Pseudomonas ARDS model.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Capillary Permeability; Disease Models, Anima | 1987 |
Treatment of porcine Pseudomonas ARDS with combination drug therapy.
Topics: Animals; Blood Pressure; Capillary Permeability; Cardiac Output; Cimetidine; Diphenhydramine; Drug C | 1987 |
Lowering pulmonary artery pressure in a patient with severe acute respiratory failure.
Topics: Blood Pressure; Humans; Hypertension, Pulmonary; Ibuprofen; Male; Middle Aged; Myocardial Infarction | 1985 |
Effect of methylprednisolone and of ibuprofen, a nonsteroidal antiinflammatory agent, on bronchoalveolar inflammation following endotoxemia.
Topics: Animals; Bronchitis; Gram-Negative Bacteria; Ibuprofen; Leukocyte Count; Methylprednisolone; Neutrop | 1985 |