ibuprofen has been researched along with Preterm Birth in 12 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
| Excerpt | Relevance | Reference |
|---|---|---|
| " Moderate certainty evidence showed a reduction in NEC following administration of a combination of species of probiotics, probiotics (any), antenatal corticosteroids in pregnant women at risk of preterm birth, and ibuprofen versus indomethacin for treatment of patent ductus arteriosus (PDA)." | 5.05 | An Overview of Systematic Reviews of Randomized-Controlled Trials for Preventing Necrotizing Enterocolitis in Preterm Infants. ( Ei-Saie, A; Maheshwari, A; Neu, J; Pammi, M; Xiong, T, 2020) |
| " Developing modelling and simulation tools, such as physiologically based pharmacokinetic (PBPK) models that incorporate developmental physiology and maturation of drug metabolism, can be used to predict drug exposure in this group of patients, and may help to optimize drug dose adjustment." | 2.94 | Preterm Physiologically Based Pharmacokinetic Model. Part II: Applications of the Model to Predict Drug Pharmacokinetics in the Preterm Population. ( Abduljalil, K; Jamei, M; Johnson, TN; Pan, X; Pansari, A, 2020) |
| "Population pharmacokinetic modelling was performed in nonlinear mixed-effect modelling software (NONMEM version 6." | 1.38 | Maturation of the glomerular filtration rate in neonates, as reflected by amikacin clearance. ( Allegaert, K; Danhof, M; De Cock, RF; de Hoog, M; Knibbe, CA; Schreuder, MF; Sherwin, CM; van den Anker, JN, 2012) |
| "Treatment with ibuprofen is safer, decreasing the risk of renal failure, thrombocytopenia, and hyponatremia." | 1.36 | Treatment of patent ductus arteriosus: indomethacin or ibuprofen? ( Bello, R; Birk, E; Hernandez, A; Klinger, G; Linder, N; Pushkov, Y; Rosen, C; Sirota, L, 2010) |
| "Ibuprofen treatment for PDA closure in the preterm baboon neonate is not associated with any increased risk of neuropathology or alterations to brain growth and development." | 1.36 | Ibuprofen treatment for closure of patent ductus arteriosus is not associated with increased risk of neuropathology. ( Clyman, RI; Inder, TE; Loeliger, M; McCurnin, D; Rees, SM; Shields, A; Yoder, B, 2010) |
| "CYP2C polymorphism was not associated with PDA response to ibuprofen and this factor appears not appropriate to optimize the ductal closure rate by modulating ibuprofen dosing strategy." | 1.36 | Are cytochrome P450 CYP2C8 and CYP2C9 polymorphisms associated with ibuprofen response in very preterm infants? ( Alberti, C; Aujard, Y; Barre, J; Baud, O; Danan, C; Decobert, F; Durrmeyer, X; Hovhannisyan, S; Jacqz-Aigrain, E; Médard, Y, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 6 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martini, S | 1 |
| Vitali, F | 1 |
| Capelli, I | 1 |
| Donadei, C | 1 |
| Raschi, E | 1 |
| Aiello, V | 1 |
| Corvaglia, L | 1 |
| De Ponti, F | 1 |
| Poluzzi, E | 1 |
| Galletti, S | 1 |
| Utsumi, M | 1 |
| Motoki, N | 1 |
| Yokota, S | 1 |
| Kobayashi, H | 1 |
| Yamazaki, S | 1 |
| Miyosawa, Y | 1 |
| Villamor, E | 1 |
| Borges-Luján, M | 1 |
| González-Luis, G | 1 |
| Abduljalil, K | 1 |
| Pan, X | 1 |
| Pansari, A | 1 |
| Jamei, M | 1 |
| Johnson, TN | 1 |
| Xiong, T | 1 |
| Maheshwari, A | 1 |
| Neu, J | 1 |
| Ei-Saie, A | 1 |
| Pammi, M | 1 |
| Faim, DRO | 1 |
| Tiago, JAM | 1 |
| Castelo, RJS | 1 |
| Francisco, ASS | 1 |
| Alves, RR | 1 |
| Pires, AMGS | 1 |
| Linder, N | 1 |
| Bello, R | 1 |
| Hernandez, A | 1 |
| Rosen, C | 1 |
| Birk, E | 1 |
| Sirota, L | 1 |
| Pushkov, Y | 1 |
| Klinger, G | 1 |
| Loeliger, M | 1 |
| Shields, A | 1 |
| McCurnin, D | 3 |
| Clyman, RI | 3 |
| Yoder, B | 2 |
| Inder, TE | 1 |
| Rees, SM | 1 |
| Durrmeyer, X | 1 |
| Hovhannisyan, S | 1 |
| Médard, Y | 1 |
| Jacqz-Aigrain, E | 1 |
| Decobert, F | 1 |
| Barre, J | 1 |
| Alberti, C | 1 |
| Aujard, Y | 1 |
| Danan, C | 1 |
| Baud, O | 1 |
| De Cock, RF | 1 |
| Allegaert, K | 1 |
| Schreuder, MF | 1 |
| Sherwin, CM | 1 |
| de Hoog, M | 1 |
| van den Anker, JN | 1 |
| Danhof, M | 1 |
| Knibbe, CA | 1 |
| Sutherland, MR | 1 |
| Yoder, BA | 1 |
| Seidner, S | 1 |
| Gubhaju, L | 1 |
| Black, MJ | 1 |
| Chang, LY | 1 |
| Shaul, PW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Amikacin Pharmacokinetics to Optimize Dosing Recommendations and Patho(Physiological) Considerations in Neonates With Perinatal Asphyxia Treated With Hypothermia[NCT04867993] | 80 participants (Anticipated) | Interventional | 2018-08-28 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for ibuprofen and Preterm Birth
| Article | Year |
|---|---|
Association of patent ductus arteriosus with fetal factors and endotypes of prematurity.
Topics: Ductus Arteriosus, Patent; Female; Fetal Growth Retardation; Humans; Ibuprofen; Indomethacin; Infant | 2023 |
An Overview of Systematic Reviews of Randomized-Controlled Trials for Preventing Necrotizing Enterocolitis in Preterm Infants.
Topics: Administration, Oral; Adrenal Cortex Hormones; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing | 2020 |
1 trial available for ibuprofen and Preterm Birth
| Article | Year |
|---|---|
Preterm Physiologically Based Pharmacokinetic Model. Part II: Applications of the Model to Predict Drug Pharmacokinetics in the Preterm Population.
Topics: Administration, Intravenous; Administration, Oral; Alfentanil; Anti-Bacterial Agents; Caffeine; Comp | 2020 |
9 other studies available for ibuprofen and Preterm Birth
| Article | Year |
|---|---|
Impact of nephrotoxic drugs on urinary biomarkers of renal function in very preterm infants.
Topics: Acute Kidney Injury; Amikacin; Biomarkers; Female; Humans; Ibuprofen; Infant; Infant, Newborn; Infan | 2022 |
Predictors of a non-response to prophylactic indomethacin for patent ductus arteriosus in preterm infants.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infan | 2023 |
PATENT DUCTUS ARTERIOSUS CLOSURE: EXPERIENCE FROM A TERTIARY REFERRAL CENTER.
Topics: Acetaminophen; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; Ibuprofen; Indomethacin; | 2020 |
Treatment of patent ductus arteriosus: indomethacin or ibuprofen?
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infan | 2010 |
Ibuprofen treatment for closure of patent ductus arteriosus is not associated with increased risk of neuropathology.
Topics: Animals; Animals, Newborn; Astrocytes; Brain; Cyclooxygenase Inhibitors; Disease Models, Animal; Duc | 2010 |
Are cytochrome P450 CYP2C8 and CYP2C9 polymorphisms associated with ibuprofen response in very preterm infants?
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Ductus Arteriosus, | 2010 |
Maturation of the glomerular filtration rate in neonates, as reflected by amikacin clearance.
Topics: Age Factors; Amikacin; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; | 2012 |
Effects of ibuprofen treatment on the developing preterm baboon kidney.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Body Weight; Dri | 2012 |
Ductus arteriosus ligation and alveolar growth in preterm baboons with a patent ductus arteriosus.
Topics: Animals; Blood Pressure; Cardiac Surgical Procedures; Disease Models, Animal; Ductus Arteriosus, Pat | 2008 |