ibuprofen has been researched along with Pregnancy in 186 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test the hypothesis that ibuprofen is equivalent to acetaminophen in its effect on postpartum blood pressure in women with gestational hypertension or preeclampsia without severe features." | 9.30 | A randomized-controlled trial to assess the effect of ibuprofen on postpartum blood pressure in women with hypertensive disorders of pregnancy. ( Hesson, A; Langen, ES; Triebwasser, JE, 2019) |
| "To evaluate the effect of ibuprofen on blood pressure in women with a diagnosis of hypertensive disorders of pregnancy and mild hypertension during the immediate postpartum period." | 9.30 | Ibuprofen and Postpartum Blood Pressure in Women With Hypertensive Disorders of Pregnancy: A Randomized Controlled Trial. ( McNulty, JA; Nageotte, MP; Oakes, MC; Penfield, CA, 2019) |
| "The first-line use of ibuprofen rather than acetaminophen for postpartum pain did not lengthen the duration of severe-range hypertension in women with preeclampsia with severe features." | 9.27 | Effect of ibuprofen vs acetaminophen on postpartum hypertension in preeclampsia with severe features: a double-masked, randomized controlled trial. ( Blue, NR; Drake-Lavelle, S; Holbrook, BD; Katukuri, VR; Leeman, L; Mozurkewich, EL; Murray-Krezan, C; Weinberg, D, 2018) |
| "To compare differences in blood pressure levels between patients with severe post-partum pre-eclampsia using ibuprofen or acetaminophen." | 9.24 | Ibuprofen versus acetaminophen as a post-partum analgesic for women with severe pre-eclampsia: randomized clinical study. ( Ortega, N; Solis, V; Vigil-De Gracia, P, 2017) |
| "Pre-emptive ibuprofen treatment was found to be more effective than a placebo in pain prevention, as determined by a significantly lower need for additional analgesia: 11 of 29 (38%) vs." | 9.16 | Pre-emptive effect of ibuprofen versus placebo on pain relief and success rates of medical abortion: a double-blind, randomized, controlled study. ( Avraham, S; Duvdevani, NR; Frenkel, Y; Gat, I; Haas, J; Seidman, DS, 2012) |
| "The study was conducted to determine whether tramadol is more effective than ibuprofen for reducing pain during uterine aspiration for abortion." | 9.13 | A randomized trial of tramadol versus ibuprofen as an adjunct to pain control during vacuum aspiration abortion. ( Gilliam, M; Romero, I; Turok, D, 2008) |
| "This study was undertaken to determine whether 400 mg of prophylactic ibuprofen can alleviate pain from insertion of an intrauterine device (IUD) and to measure level of pain with improved techniques." | 9.12 | Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen. ( Chen, PL; Croxatto, H; Hubacher, D; Lillo, S; Reyes, V; Zepeda, A, 2006) |
| " The use of ibuprofen lysinate to enhance implantation has been investigated in cattle with the specific aim of improving pregnancy rates after embryo transfer." | 9.09 | Effect of a single dose of ibuprofen lysinate before embryo transfer on pregnancy rates in cows. ( Candiani, M; Covini, D; Elli, M; Frigerio, A; Gaffuri, B; Vignali, M; Zanardelli, M, 2001) |
| "The prostaglandin synthetase inhibitor ibuprofen was evaluated for relief of severe primary dysmenorrhea in a controlled, double-blind, cross-over study in seven patients for a total of 23 menstrual cycles." | 9.04 | Relief of dysmenorrhea with the prostaglandin synthetase inhibitor ibuprofen: effect on prostaglandin levels in menstrual fluid. ( Chan, WY; Dawood, MY; Fuchs, F, 1979) |
| " The earlier review included 20 studies (7238 participants) in valid comparisons, but because we used different outcomes for some headache studies, the number of participants in the analyses of the effects of caffeine is now 4262 when previously it was 5243." | 8.90 | Caffeine as an analgesic adjuvant for acute pain in adults. ( Derry, CJ; Derry, S; Moore, RA, 2014) |
| " Most studies used paracetamol or ibuprofen, with 100 mg to 130 mg caffeine, and the most common pain conditions studied were postoperative dental pain, postpartum pain, and headache." | 8.88 | Caffeine as an analgesic adjuvant for acute pain in adults. ( Derry, CJ; Derry, S; Moore, RA, 2012) |
| "In contrast to other non-steroidal anti-inflammatory drugs (NSAIDs), naproxen use during pregnancy is not well studied." | 8.02 | First trimester naproxen exposure and outcome of pregnancy - A German case series. ( Dathe, K; Fietz, AK; Hultzsch, S; Padberg, S; Paulus, W; Schaefer, C, 2021) |
| "Nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesic drugs, such as acetaminophen (APAP), are frequently taken during pregnancy, even in combination." | 7.91 | In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice. ( Boizet-Bonhoure, B; Brun, C; de Massy, B; Déjardin, S; Ghettas, A; Keime, C; Marchive, C; Nguyen, AL; Ollivier, M; Philibert, P; Poulat, F; Pruvost, A; Rossitto, M, 2019) |
| " We examined whether mother's use of paracetamol, aspirin or ibuprofen in pregnancy is associated with increased risk of cerebral palsy (CP) in the child." | 7.88 | Use of paracetamol, ibuprofen or aspirin in pregnancy and risk of cerebral palsy in the child. ( Andersen, AN; Andersen, GL; Andersen, PK; Liew, Z; Martinussen, T; Olsen, J; Petersen, TG; Rebordosa, C; Strandberg-Larsen, K; Tollånes, MC; Uldall, P; Wilcox, AJ, 2018) |
| "Ibuprofen is an analgesic frequently used in the 1st and 2nd trimester of pregnancy." | 7.88 | No evidence of adverse pregnancy outcome after exposure to ibuprofen in the first trimester - Evaluation of the national Embryotox cohort. ( Dathe, K; Fietz, AK; Hultzsch, S; Meister, R; Meixner, K; Padberg, S; Pritchard, LW; Schaefer, C, 2018) |
| "Ibuprofen exposure during the first trimester was associated with a decrease in birth weight of 79 grams (95% confidence interval -133 to -25 grams)." | 7.83 | Association of Prenatal Ibuprofen Exposure with Birth Weight and Gestational Age: A Population-Based Sibling Study. ( Nezvalová-Henriksen, K; Nordeng, H; Spigset, O; Wood, M, 2016) |
| "Unadjusted models showed an increased asthma risk in early childhood for higher infant acetaminophen (odds ratio [OR], 1." | 7.81 | Prenatal and infant exposure to acetaminophen and ibuprofen and the risk for wheeze and asthma in children. ( Bunyavanich, S; Camargo, CA; Gillman, MW; Gold, DR; Litonjua, AA; Rifas-Shiman, SL; Scirica, CV; Sordillo, JE; Weiss, ST, 2015) |
| "To investigate the individual effects of ibuprofen, diclofenac, naproxen, and piroxicam on pregnancy outcome." | 7.79 | Effects of ibuprofen, diclofenac, naproxen, and piroxicam on the course of pregnancy and pregnancy outcome: a prospective cohort study. ( Nezvalová-Henriksen, K; Nordeng, H; Spigset, O, 2013) |
| " The use of acetaminophen, ibuprofen, and acetylsalicylic acid during pregnancy was assessed in 3 computer-assisted telephone interviews and 1 self-administered questionnaire." | 7.76 | Maternal use of acetaminophen, ibuprofen, and acetylsalicylic acid during pregnancy and risk of cryptorchidism. ( Bonde, JP; Henriksen, TB; Jensen, MS; Olsen, J; Rebordosa, C; Sørensen, HT; Thulstrup, AM; Toft, G, 2010) |
| "Empirical evidence is needed to guide adequate postpartum pain relief of methadone and buprenorphine stabilized patients." | 7.75 | Management of acute postpartum pain in patients maintained on methadone or buprenorphine during pregnancy. ( Dahne, J; Johnson, R; Jones, HE; Lemoine, L; Milio, L; O'Grady, K; Ordean, A; Selby, P, 2009) |
| "Pain is often cited as one of the worst features of medical abortion." | 6.82 | Two prophylactic medication approaches in addition to a pain control regimen for early medical abortion < 63 days' gestation with mifepristone and misoprostol: study protocol for a randomized, controlled trial. ( Dragoman, MV; Dung, DL; Grossman, D; Habib, N; Huong, NM; Kapp, N; Tamang, A, 2016) |
| "Ibuprofen is a nonsteroidal antiinflammatory agent with analgesic and antipyretic activity and is an effective, primarily peripheral-acting antiinflammatory analgesic." | 6.68 | Analgesic efficacy of a hydrocodone with ibuprofen combination compared with ibuprofen alone for the treatment of acute postoperative pain. ( Doyle, R; O'Neill, E; Olson, NZ; Ramos, I; Sunshine, A, 1997) |
| "We aimed to characterize the current pain experience of patients completing an evidence-based mifepristone-misoprostol medication abortion regimen using real-time pain scores." | 5.51 | The experience of pain in real-time during medication abortion. ( Davis, J; Fontanilla, T; Friedlander, EB; Horiuchi, W; Kaneshiro, B; Raidoo, S; Salcedo, J; Soon, R; Tschann, M, 2022) |
| "To compare the overnight maximum pain scores after osmotic dilator placement prior to a dilation and evacuation (D&E) procedure in participants assigned to a prescription for ibuprofen alone or to ibuprofen plus oxycodone." | 5.41 | Opioid prescription for pain after osmotic dilator placement in abortion care: A randomized controlled trial. ( McAllister, A; Nagendra, D; Roe, AH; Sammel, MD; Schreiber, CA; Schurr, D; Shorter, JM; Sonalkar, S, 2021) |
| "To evaluate whether prophylactic dronabinol, a synthetic tetrahydrocannabinol, reduces pain during medical abortion." | 5.34 | Cannabinoids for Pain Control During Medical Abortion: A Randomized Controlled Trial. ( Alton, K; Bayer, LL; Beardsworth, K; Bednarek, PH; Colwill, AC; Edelman, A; Garg, B; Jensen, JT, 2020) |
| "To test the hypothesis that ibuprofen is equivalent to acetaminophen in its effect on postpartum blood pressure in women with gestational hypertension or preeclampsia without severe features." | 5.30 | A randomized-controlled trial to assess the effect of ibuprofen on postpartum blood pressure in women with hypertensive disorders of pregnancy. ( Hesson, A; Langen, ES; Triebwasser, JE, 2019) |
| "To evaluate the effect of ibuprofen on blood pressure in women with a diagnosis of hypertensive disorders of pregnancy and mild hypertension during the immediate postpartum period." | 5.30 | Ibuprofen and Postpartum Blood Pressure in Women With Hypertensive Disorders of Pregnancy: A Randomized Controlled Trial. ( McNulty, JA; Nageotte, MP; Oakes, MC; Penfield, CA, 2019) |
| "To assess pain-management using auricular acupuncture as an adjunct to ibuprofen and paracervical block during first trimester uterine aspiration, and to assess auricular acupuncture's effect on anxiety." | 5.30 | Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial. ( Danvers, A; Gold, MA; Morrow, L; Ndubisi, C; Westhoff, CL, 2019) |
| "The first-line use of ibuprofen rather than acetaminophen for postpartum pain did not lengthen the duration of severe-range hypertension in women with preeclampsia with severe features." | 5.27 | Effect of ibuprofen vs acetaminophen on postpartum hypertension in preeclampsia with severe features: a double-masked, randomized controlled trial. ( Blue, NR; Drake-Lavelle, S; Holbrook, BD; Katukuri, VR; Leeman, L; Mozurkewich, EL; Murray-Krezan, C; Weinberg, D, 2018) |
| "To compare differences in blood pressure levels between patients with severe post-partum pre-eclampsia using ibuprofen or acetaminophen." | 5.24 | Ibuprofen versus acetaminophen as a post-partum analgesic for women with severe pre-eclampsia: randomized clinical study. ( Ortega, N; Solis, V; Vigil-De Gracia, P, 2017) |
| " Only one study found evidence of an effect between interventions on pain score: a prophylactic dose of ibuprofen 1600 mg likely reduces the pain score when compared to a dose of paracetamol 2000 mg (mean difference (MD) 2." | 5.22 | Pain management for medical abortion before 14 weeks' gestation. ( Cameron, S; Morroni, C; Reynolds-Wright, JJ; Woldetsadik, MA, 2022) |
| " Only one study found evidence of an effect between interventions on pain score: a prophylactic dose of ibuprofen 1600mg likely reduces the pain score when compared to a dose of paracetamol 2000mg (MD 2." | 5.22 | Pain management for medical abortion before 14 weeks' gestation: A systematic review. ( Cameron, ST; Morroni, C; Reynolds-Wright, JJ; Woldetsadik, MA, 2022) |
| "Pre-emptive ibuprofen treatment was found to be more effective than a placebo in pain prevention, as determined by a significantly lower need for additional analgesia: 11 of 29 (38%) vs." | 5.16 | Pre-emptive effect of ibuprofen versus placebo on pain relief and success rates of medical abortion: a double-blind, randomized, controlled study. ( Avraham, S; Duvdevani, NR; Frenkel, Y; Gat, I; Haas, J; Seidman, DS, 2012) |
| "To study the effects of a paracervical block with combined ketorolac and lidocaine on perceived pain during first-trimester surgical abortion." | 5.14 | Paracervical block with combined ketorolac and lidocaine in first-trimester surgical abortion: a randomized controlled trial. ( Burke, A; Cansino, C; Edelman, A; Jamshidi, R, 2009) |
| "The study was conducted to determine whether tramadol is more effective than ibuprofen for reducing pain during uterine aspiration for abortion." | 5.13 | A randomized trial of tramadol versus ibuprofen as an adjunct to pain control during vacuum aspiration abortion. ( Gilliam, M; Romero, I; Turok, D, 2008) |
| "This study was undertaken to determine whether 400 mg of prophylactic ibuprofen can alleviate pain from insertion of an intrauterine device (IUD) and to measure level of pain with improved techniques." | 5.12 | Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen. ( Chen, PL; Croxatto, H; Hubacher, D; Lillo, S; Reyes, V; Zepeda, A, 2006) |
| "In a double-blind, placebo-controlled study, 100 patients scheduled for elective termination of pregnancy were randomised to receive placebo, oral ibuprofen 400 mg, oral dextromethorphan 120 mg, or a combination of ibuprofen 400 mg and dextromethorphan 120 mg, 1 h before surgery." | 5.09 | The effect of dextromethorphan, alone or in combination with ibuprofen, on postoperative pain after minor gynaecological surgery. ( Bach, LF; Dahl, JB; Ilkjaer, S; Nielsen, PA; Wernberg, M, 2000) |
| " The use of ibuprofen lysinate to enhance implantation has been investigated in cattle with the specific aim of improving pregnancy rates after embryo transfer." | 5.09 | Effect of a single dose of ibuprofen lysinate before embryo transfer on pregnancy rates in cows. ( Candiani, M; Covini, D; Elli, M; Frigerio, A; Gaffuri, B; Vignali, M; Zanardelli, M, 2001) |
| "Phase 1: ibuprofen reduced pain scores more than placebo with the improvement being greatest for the postoperative period." | 5.08 | Pain control in abortion. ( Rawling, M; Wiebe, ER, 1995) |
| " Moderate certainty evidence showed a reduction in NEC following administration of a combination of species of probiotics, probiotics (any), antenatal corticosteroids in pregnant women at risk of preterm birth, and ibuprofen versus indomethacin for treatment of patent ductus arteriosus (PDA)." | 5.05 | An Overview of Systematic Reviews of Randomized-Controlled Trials for Preventing Necrotizing Enterocolitis in Preterm Infants. ( Ei-Saie, A; Maheshwari, A; Neu, J; Pammi, M; Xiong, T, 2020) |
| "The prostaglandin synthetase inhibitor ibuprofen was evaluated for relief of severe primary dysmenorrhea in a controlled, double-blind, cross-over study in seven patients for a total of 23 menstrual cycles." | 5.04 | Relief of dysmenorrhea with the prostaglandin synthetase inhibitor ibuprofen: effect on prostaglandin levels in menstrual fluid. ( Chan, WY; Dawood, MY; Fuchs, F, 1979) |
| " The earlier review included 20 studies (7238 participants) in valid comparisons, but because we used different outcomes for some headache studies, the number of participants in the analyses of the effects of caffeine is now 4262 when previously it was 5243." | 4.90 | Caffeine as an analgesic adjuvant for acute pain in adults. ( Derry, CJ; Derry, S; Moore, RA, 2014) |
| " Most studies used paracetamol or ibuprofen, with 100 mg to 130 mg caffeine, and the most common pain conditions studied were postoperative dental pain, postpartum pain, and headache." | 4.88 | Caffeine as an analgesic adjuvant for acute pain in adults. ( Derry, CJ; Derry, S; Moore, RA, 2012) |
| " Up to the present day, several cases of severe and sometimes irreversible renal insufficiency have been described in neonates exposed to indomethacin prenatally or in the first days of life for treatment of patent ductus arteriosus (PDA)." | 4.81 | NSAID-induced nephrotoxicity from the fetus to the child. ( Cuzzolin, L; Dal Cerè, M; Fanos, V, 2001) |
| "In contrast to other non-steroidal anti-inflammatory drugs (NSAIDs), naproxen use during pregnancy is not well studied." | 4.02 | First trimester naproxen exposure and outcome of pregnancy - A German case series. ( Dathe, K; Fietz, AK; Hultzsch, S; Padberg, S; Paulus, W; Schaefer, C, 2021) |
| "Examine associations of acetaminophen and ibuprofen use during pregnancy and infancy with executive function and behaviour problems in children." | 3.96 | Associations of prenatal or infant exposure to acetaminophen or ibuprofen with mid-childhood executive function and behaviour. ( Bertoldi, AD; Cardenas, A; Hivert, MF; Oken, E; Rifas-Shiman, SL; Tiemeier, H, 2020) |
| " Pain medication consisted of ibuprofen 600 mg and paracetamol 1000 mg, first doses taken simultaneously with misoprostol and repeated, if needed, up to three times daily." | 3.96 | Pain during medical abortion in early pregnancy in teenage and adult women. ( Heikinheimo, O; Kemppainen, V; Mentula, M; Palkama, V, 2020) |
| "Nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesic drugs, such as acetaminophen (APAP), are frequently taken during pregnancy, even in combination." | 3.91 | In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice. ( Boizet-Bonhoure, B; Brun, C; de Massy, B; Déjardin, S; Ghettas, A; Keime, C; Marchive, C; Nguyen, AL; Ollivier, M; Philibert, P; Poulat, F; Pruvost, A; Rossitto, M, 2019) |
| " For asthma, albuterol was reported most frequently (77." | 3.88 | Agreement Between Maternal Report and Medical Records During Pregnancy: Medications for Rheumatoid Arthritis and Asthma. ( Ansari, S; Bandoli, G; Chambers, CD; Hulugalle, A; Kuo, GM; Palmsten, K; Xu, R, 2018) |
| "Male gender, chorioamnionitis, early sepsis, asphyxia, hemodynamic PDA, persistent hypotension, ibuprofen and paracetamol usage, and orogastric catheter administration were the main risk factors for gastric perforations in VLBW infants." | 3.88 | Neonatal gastric perforations in very low birth weight infants: a single center experience and review of the literature. ( Babayigit, A; Cetinkaya, M; Ozaydın, S; Sander, S, 2018) |
| " We examined whether mother's use of paracetamol, aspirin or ibuprofen in pregnancy is associated with increased risk of cerebral palsy (CP) in the child." | 3.88 | Use of paracetamol, ibuprofen or aspirin in pregnancy and risk of cerebral palsy in the child. ( Andersen, AN; Andersen, GL; Andersen, PK; Liew, Z; Martinussen, T; Olsen, J; Petersen, TG; Rebordosa, C; Strandberg-Larsen, K; Tollånes, MC; Uldall, P; Wilcox, AJ, 2018) |
| "Ibuprofen is an analgesic frequently used in the 1st and 2nd trimester of pregnancy." | 3.88 | No evidence of adverse pregnancy outcome after exposure to ibuprofen in the first trimester - Evaluation of the national Embryotox cohort. ( Dathe, K; Fietz, AK; Hultzsch, S; Meister, R; Meixner, K; Padberg, S; Pritchard, LW; Schaefer, C, 2018) |
| "Women who used naproxen or opioids had slightly lower fecundability than women who did not use any pain-relieving medications; use of acetaminophen, aspirin and ibuprofen was not appreciably associated with fecundability." | 3.85 | Preconception use of pain-relievers and time-to-pregnancy: a prospective cohort study. ( Hatch, EE; McInerney, KA; Mikkelsen, EM; Rothman, KJ; Wesselink, AK; Wise, LA, 2017) |
| "Ibuprofen exposure during the first trimester was associated with a decrease in birth weight of 79 grams (95% confidence interval -133 to -25 grams)." | 3.83 | Association of Prenatal Ibuprofen Exposure with Birth Weight and Gestational Age: A Population-Based Sibling Study. ( Nezvalová-Henriksen, K; Nordeng, H; Spigset, O; Wood, M, 2016) |
| "Unadjusted models showed an increased asthma risk in early childhood for higher infant acetaminophen (odds ratio [OR], 1." | 3.81 | Prenatal and infant exposure to acetaminophen and ibuprofen and the risk for wheeze and asthma in children. ( Bunyavanich, S; Camargo, CA; Gillman, MW; Gold, DR; Litonjua, AA; Rifas-Shiman, SL; Scirica, CV; Sordillo, JE; Weiss, ST, 2015) |
| "To investigate the individual effects of ibuprofen, diclofenac, naproxen, and piroxicam on pregnancy outcome." | 3.79 | Effects of ibuprofen, diclofenac, naproxen, and piroxicam on the course of pregnancy and pregnancy outcome: a prospective cohort study. ( Nezvalová-Henriksen, K; Nordeng, H; Spigset, O, 2013) |
| "Hypertension during pregnancy, even without intrauterine growth restriction, appeared to carry the same risk for MRB as exposure to ibuprofen and extrauterine growth restriction." | 3.79 | Risk factors of mild rectal bleeding in very low birth weight infants: a case control study. ( Ben Said, M; Hays, S; Jordan, I; Maucort-Boulch, D; Oulmaati, A; Picaud, JC, 2013) |
| " The use of acetaminophen, ibuprofen, and acetylsalicylic acid during pregnancy was assessed in 3 computer-assisted telephone interviews and 1 self-administered questionnaire." | 3.76 | Maternal use of acetaminophen, ibuprofen, and acetylsalicylic acid during pregnancy and risk of cryptorchidism. ( Bonde, JP; Henriksen, TB; Jensen, MS; Olsen, J; Rebordosa, C; Sørensen, HT; Thulstrup, AM; Toft, G, 2010) |
| "Empirical evidence is needed to guide adequate postpartum pain relief of methadone and buprenorphine stabilized patients." | 3.75 | Management of acute postpartum pain in patients maintained on methadone or buprenorphine during pregnancy. ( Dahne, J; Johnson, R; Jones, HE; Lemoine, L; Milio, L; O'Grady, K; Ordean, A; Selby, P, 2009) |
| " IBU blocked LPS-induced fever but did not block LPS-induced increases in plasma cytokines and corticosterone in the pregnant dam." | 3.75 | Effects of prenatal immune activation on hippocampal neurogenesis in the rat. ( Ashdown, H; Boksa, P; Cui, K; Luheshi, GN, 2009) |
| " Fifteen percent of the pregnant women took ibuprofen at some point during the pregnancy (5." | 3.72 | Prescription, over-the-counter, and herbal medicine use in a rural, obstetric population. ( Amonkar, M; Glover, DD; Rybeck, BF; Tracy, TS, 2003) |
| "We confirm by meconium analysis the results of previous studies that demonstrated that the use of NSAIDs during pregnancy, particularly aspirin, ibuprofen, and naproxen, is high; is grossly underestimated by maternal history; and is significantly associated with PPHN." | 3.71 | Analysis of nonsteroidal antiinflammatory drugs in meconium and its relation to persistent pulmonary hypertension of the newborn. ( Alano, MA; Konduri, GG; Ngougmna, E; Ostrea, EM, 2001) |
| "In isolated, perfused mesenteric vascular beds from female rats, it was assessed whether the constrictor response to cirazoline, an alpha(1)-adrenergic agonist, or acetylcholine (ACh)-induced relaxation was altered by oestrous cycle or pregnancy and the ability of nitric oxide (NO), prostanoids and endothelium-derived hyperpolarizing factor (EDHF) to modulate these responses." | 3.70 | Influence of oestrous cycle and pregnancy on the reactivity of the rat mesenteric vascular bed. ( Adeagbo, AS; Alsip, NL; Dalle Lucca, JJ, 2000) |
| "Previous studies have shown that epidermal growth factor (EGF) can replace estrogen for initiating embryo implantation in hypophysectomized rats in which pregnancy was maintained with progesterone, provided that uterine trauma preceded the intravenous dose of the growth factor." | 3.69 | The role of arachidonic acid and/or its metabolites in embryo implantation initiated by epidermal growth factor (EGF). ( Chatterjee, S; Johnson, DC, 1995) |
| "Ingestion of the anticonvulsant drug valproic acid and of the angiotensin converting enzyme inhibitor captopril during pregnancy has been associated with abnormal fetal outcome in humans." | 3.69 | Evaluation of the rat embryo culture system as a predictive test for human teratogens. ( Buttar, HS; Guest, I; Smith, S; Varma, DR, 1994) |
| "In order to investigate whether amniotic fluid could induce the release of mediators from blood cells which would damage the lungs, an isolated perfused rabbit lung (IPRL) was exposed to amniotic fluid embolism-like plasma (AFEP) and the injury of AFEP to lungs and the protective effects of ibuprofen were studied." | 3.69 | [Effects of amniotic fluid embolism-like plasma on isolated perfused rabbit lungs]. ( Bahrami, S; Jin, Z; Yu, Y, 1997) |
| "Three antiprostaglandin drugs, acetylsalicylic acid, indomethacin and ibuprofen, were administered intraluminally at different does to pregnant rats on Day 4 of pregnancy." | 3.66 | Effect of intrauterine administration of antiprostaglandin drugs on implantation in the rat. ( Chaudhury, RR; Gupta, U; Malhotra, N; Varma, SK, 1981) |
| " After culture, embryo morphological and developmental parameters were documented using standardized scoring systems at each dosage concentration." | 2.82 | Assessment of embryo morphology following perinatal exposure to aspirin, ibuprofen and paracetamol using whole embryo culture system. ( Leung, BW; Leung, TY; Moungmaithong, S; Poon, LC; Sahota, DS; Wang, CC, 2022) |
| "Ibuprofen use was associated with a decrease in risk for type 1 ovarian cancer." | 2.82 | Differences in risk for type 1 and type 2 ovarian cancer in a large cancer screening trial. ( Ahn, HJ; Kessel, B; Terada, KY, 2016) |
| "Pain is often cited as one of the worst features of medical abortion." | 2.82 | Two prophylactic medication approaches in addition to a pain control regimen for early medical abortion < 63 days' gestation with mifepristone and misoprostol: study protocol for a randomized, controlled trial. ( Dragoman, MV; Dung, DL; Grossman, D; Habib, N; Huong, NM; Kapp, N; Tamang, A, 2016) |
| "Ibuprofen was consistently better than acetaminophen at 1 hour after treatment for relief of perineal pain after childbirth without any side effects." | 2.73 | Ibuprofen versus acetaminophen for the relief of perineal pain after childbirth: a randomized controlled trial. ( Kamondetdecha, R; Tannirandorn, Y, 2008) |
| " Observations collected in two population pharmacokinetic studies, in preterm neonates, investigating amikacin and vancomycin were used to estimate: i) the impact of ibuprofen administration on the clearance of these drugs; and ii) the difference between prophylactic and therapeutic administration of ibuprofen on this clearance." | 2.72 | Impact of ibuprofen administration on renal drug clearance in the first weeks of life. ( Allegaert, K; Anderson, BJ; Rayyan, M, 2006) |
| "Quinacrine sterilization has the potential to meet the unmet need for female sterilization in developing countries without access to trained personnel and sophisticated surgical equipment." | 2.68 | Quinacrine pellet nonsurgical female sterilization in Wonosobo, Indonesia. ( Soejoenoes, A; Suhadi, A, 1997) |
| "Ibuprofen is a nonsteroidal antiinflammatory agent with analgesic and antipyretic activity and is an effective, primarily peripheral-acting antiinflammatory analgesic." | 2.68 | Analgesic efficacy of a hydrocodone with ibuprofen combination compared with ibuprofen alone for the treatment of acute postoperative pain. ( Doyle, R; O'Neill, E; Olson, NZ; Ramos, I; Sunshine, A, 1997) |
| "Ibuprofen was more effective after one hour than either of the other two drugs, whatever the scale or parameter used." | 2.67 | [Analgesic effect of ibuprofen in pain after episiotomy]. ( Barrat, J; Behotas, S; Boureau, F; Castiel, J; Chauvin, A; Lienhart, A; Martin, A, 1992) |
| "Codeine 60 mg was statistically superior to placebo based on TOTPAR, the global ratings, and a few hourly measures." | 2.66 | Analgesic efficacy of two ibuprofen-codeine combinations for the treatment of postepisiotomy and postoperative pain. ( Laska, EM; Olson, N; Rivera, J; Roure, C; Sunshine, A; Zorrilla, C, 1987) |
| "At one year of life, profound sensorineural hearing loss was observed re quiring a cochlear implant." | 2.61 | Bartter syndrome: An infrequent tubulopathy of prenatal onset. ( Caviedes R, N; Gómez de la F, CL; Novoa P, JM, 2019) |
| " On the other hand, several adverse effects have been reported with such medications, including peripheral vasoconstriction, gastrointestinal bleeding and perforation, weakened platelet aggregation, hyperbilirubinemia and renal failure." | 2.52 | Safety of therapeutics used in management of patent ductus arteriosus in preterm infants. ( Erdeve, O; Oncel, MY, 2015) |
| "The treatment with ibuprofen reduces the urine output and increases the serum creatinine concentrations less extensively than indomethacin." | 2.50 | Clinical pharmacology of ibuprofen and indomethacin in preterm infants with patent ductus arteriosus. ( Pacifici, GM, 2014) |
| "Ibuprofen lysine has demonstrated significantly less effects on cerebral, renal, and mesenteric blood flow in premature neonates when compared with indomethacin." | 2.44 | Ibuprofen lysine for the prevention and treatment of patent ductus arteriosus. ( Pai, VB; Puthoff, TD; Sakadjian, A, 2008) |
| "Ibuprofen is a non-selective cyclooxygenase (COX) inhibitor with analgesic, antipyretic and antiinflammatory activity." | 2.41 | [Current opinions on embryotoxic and teratogenic effects of ibuprofen]. ( Bełzek, A; Burdan, F, 2001) |
| "Prochlorperazine injection has been upgraded to a highly recommended level because of the rich clinical experience for this treatment." | 1.72 | 2022 Taiwan Guidelines for Acute Treatment of Migraine. ( Lau, CI; Wang, YF, 2022) |
| " Initial dosing consisted of indomethacin, followed by ibuprofen in most cases." | 1.62 | Effect of In Utero Non-Steroidal Anti-Inflammatory Drug Therapy for Severe Ebstein Anomaly or Tricuspid Valve Dysplasia (NSAID Therapy for Fetal Ebstein anomaly). ( Beroukhim, RS; Cumbermack, KM; Ferrer, Q; Freud, LR; Glickstein, JS; LaFranchi, T; Makhoul, M; Morris, SA; Pedra, SR; Phoon, CK; Sun, HY; Tworetzky, W; Wilkins-Haug, LE, 2021) |
| " Results The scheduled dosing group was found to have a statistically significant decrease in pain scores at all time intervals." | 1.56 | The effect of a scheduled regimen of acetaminophen and ibuprofen on opioid use following cesarean delivery. ( Chappelle, J; Poljak, D, 2020) |
| " We conclude that repeated dosing through transversus abdominis plane catheters may be offered to women as an alternative or adjuvant to intrathecal morphine." | 1.38 | Transversus abdominis plane catheters for post-cesarean delivery analgesia: a series of five cases. ( Bollag, L; Landau, R; Ortner, C; Richebe, P, 2012) |
| "The effect of patent ductus arteriosus (PDA) treatment with cyclooxygenase (COX) inhibitors (indomethacin [INDO] and ibuprofen [IBU]) on regional oxygenation requires further clarification." | 1.38 | Does treatment of patent ductus arteriosus with cyclooxygenase inhibitors affect neonatal regional tissue oxygenation? ( Bhatt, M; Mehta, R; Petrova, A, 2012) |
| "Ibuprofen-treatment has no effect on the expression of genes that regulate pulmonary inflammation but does increase the expression of alpha-ENaC (the transepithelial sodium channel that is critical for alveolar water clearance)." | 1.37 | Patent ductus arteriosus ligation alters pulmonary gene expression in preterm baboons. ( Clyman, RI; McCurnin, DC; Shaul, PW; Waleh, N; Yoder, BA, 2011) |
| " An ibuprofen dosage of 1,600 mg/day did not induce LUF syndrome either at continuous periovulatory or discontinuous exposure." | 1.37 | Luteinized unruptured follicle syndrome increased by inactive disease and selective cyclooxygenase 2 inhibitors in women with inflammatory arthropathies. ( Micu, MC; Micu, R; Ostensen, M, 2011) |
| "The prognosis of breast cancer in young women is influenced by reproductive history." | 1.37 | Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2. ( Borges, VF; Conklin, MW; Eliceiri, KW; Keely, PJ; Lyons, TR; Marusyk, A; O'Brien, J; Schedin, P; Tan, AC, 2011) |
| "CYP2C polymorphism was not associated with PDA response to ibuprofen and this factor appears not appropriate to optimize the ductal closure rate by modulating ibuprofen dosing strategy." | 1.36 | Are cytochrome P450 CYP2C8 and CYP2C9 polymorphisms associated with ibuprofen response in very preterm infants? ( Alberti, C; Aujard, Y; Barre, J; Baud, O; Danan, C; Decobert, F; Durrmeyer, X; Hovhannisyan, S; Jacqz-Aigrain, E; Médard, Y, 2010) |
| "Lower GA (P<0." | 1.35 | Factors affecting postnatal changes in serum creatinine in preterm infants with gestational age <32 weeks. ( Bonsante, F; Ferdinus, C; Gouyon, JB; Iacobelli, S; Labenne, M, 2009) |
| "Indomethacin is used to close the patent ductus arteriosus in premature infants and for tocolysis of preterm labor." | 1.35 | Delayed neonatal closure of the ductus arteriosus following early in utero exposure to indomethacin in the rat. ( Imamura, S; Ito, K; Momma, K; Nakanishi, T; Sugiyama, K; Sun, F; Toyoshima, K, 2009) |
| "Indomethacin is known to cause renal failure in up to 25% of infants treated." | 1.34 | Renal glomeruli and tubular injury following indomethacin, ibuprofen, and gentamicin exposure in a neonatal rat model. ( Dahlstrom, JE; Falk, MC; Kent, AL; Koina, ME; Maxwell, LE; Willenborg, D, 2007) |
| " Unlike general toxicity data, their prenatal toxic effects were not extensively studied before." | 1.33 | Comparison of developmental toxicity of selective and non-selective cyclooxygenase-2 inhibitors in CRL:(WI)WUBR Wistar rats--DFU and piroxicam study. ( Burdan, F, 2005) |
| "Tolmetin and ibuprofen were administered three times a day." | 1.33 | Skeletal developmental effects of selective and nonselective cyclooxygenase-2 inhibitors administered through organogenesis and fetogenesis in Wistar CRL:(WI)WUBR rats. ( Burdan, F; Dudka, J; Klepacz, R; Marzec, B; Szumilo, J, 2005) |
| "Ibuprofen inhibit the enzyme cyclo-oxygenase and thereby block the prostaglandin synthesis in the kidneys." | 1.32 | The effect of the cyclooxygenase blockers, ibuprofen on the development of glomeruli in Sprague-Dawley rats. ( Akinola, O; Kusemiju, O; Noronha, C; Okanlawon, OA; Oremosu, A, 2003) |
| "Both COX inhibitors were toxic to dams in the highest doses evaluated, which caused a significantly greater incidence of intrauterine growth retardation and developmental variations." | 1.32 | Developmental toxicity evaluation of ibuprofen and tolmetin administered in triple daily doses to Wistar CRL:(WI)WUBR rats. ( Burdan, F, 2004) |
| "Smoking is a documented risk factor for pancreatic cancer, and the risk is increased in smokers who also consume alcohol." | 1.31 | The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK. ( Castonguay, A; Miller, MS; Schuller, HM; Walker, K; Weddle, DL; Zhang, L, 2002) |
| "Cirazoline-induced tone was smaller in the pregnant compared with the proestrous group." | 1.31 | Oestrous cycle and pregnancy alter the reactivity of the rat uterine vasculature. ( Adeagbo, AS; Alsip, NL; Dalle Lucca, JJ, 2000) |
| "Previous studies of gastroschisis have suggested that risk is increased for maternal use of vasoactive over-the-counter medications, including specific analgesics and decongestants." | 1.31 | Maternal medication use and risks of gastroschisis and small intestinal atresia. ( Mitchell, AA; Sheehan, JE; Werler, MM, 2002) |
| "A case is reported of presumed twin-twin transfusion syndrome successfully treated with amniocentesis and also complicated by congenital cytomegalovirus infection and second trimester exposure to high-dose ibuprofen with temporally related ductal narrowing." | 1.29 | "Stuck twin" syndrome associated with congenital cytomegalovirus infection. ( Baker, ER; Brown, ZA; Eberhardt, H, 1993) |
| "Uterine leiomyomas are found in approximately 2% of pregnant women." | 1.28 | Complications of uterine leiomyomas in pregnancy. ( Dotters, DJ; Droegemeuller, W; Katz, VL, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (10.75) | 18.7374 |
| 1990's | 17 (9.14) | 18.2507 |
| 2000's | 50 (26.88) | 29.6817 |
| 2010's | 69 (37.10) | 24.3611 |
| 2020's | 30 (16.13) | 2.80 |
| Authors | Studies |
|---|---|
| Moungmaithong, S | 1 |
| Leung, BW | 1 |
| Sahota, DS | 1 |
| Wang, CC | 1 |
| Leung, TY | 1 |
| Poon, LC | 1 |
| Friedlander, EB | 1 |
| Raidoo, S | 1 |
| Soon, R | 2 |
| Salcedo, J | 2 |
| Davis, J | 1 |
| Tschann, M | 2 |
| Fontanilla, T | 2 |
| Horiuchi, W | 1 |
| Kaneshiro, B | 2 |
| Moayedi, G | 1 |
| Stevens, K | 1 |
| Bednarek, PH | 2 |
| Reynolds-Wright, JJ | 2 |
| Woldetsadik, MA | 2 |
| Morroni, C | 2 |
| Cameron, S | 2 |
| Cameron, ST | 1 |
| Indermuhle, P | 1 |
| Zelko, M | 1 |
| Mori, C | 1 |
| Chiu, SH | 1 |
| Lau, CI | 1 |
| Wang, YF | 1 |
| Kaur, S | 2 |
| Manerkar, S | 1 |
| Mondkar, J | 1 |
| Kalamdani, P | 1 |
| Patra, S | 1 |
| Kalathingal, T | 1 |
| Philibert, P | 3 |
| Déjardin, S | 2 |
| Girard, M | 1 |
| Durix, Q | 1 |
| Gonzalez, AA | 1 |
| Mialhe, X | 1 |
| Tardat, M | 1 |
| Poulat, F | 3 |
| Boizet-Bonhoure, B | 3 |
| Fowler, C | 1 |
| Chu, AW | 1 |
| Guo, N | 1 |
| Ansari, JR | 1 |
| Shafer, SL | 1 |
| Flood, PD | 1 |
| Zhong, B | 1 |
| Tan, K | 1 |
| Razak, A | 1 |
| Sackett, V | 1 |
| Machipisa, C | 1 |
| Zhou, L | 1 |
| Samiee-Zafarghandy, S | 1 |
| Sehgal, A | 1 |
| Hunt, RW | 1 |
| Pharande, P | 1 |
| Malhotra, A | 1 |
| Carneiro, L | 1 |
| Bouissou, A | 1 |
| Favrais, G | 1 |
| Rossitto, M | 2 |
| Ollivier, M | 1 |
| Pruvost, A | 2 |
| Brun, C | 1 |
| Marchive, C | 2 |
| Nguyen, AL | 1 |
| Ghettas, A | 2 |
| Keime, C | 1 |
| de Massy, B | 1 |
| Fiala, C | 1 |
| Agostini, A | 1 |
| Bombas, T | 1 |
| Lertxundi, R | 1 |
| Lubusky, M | 1 |
| Parachini, M | 1 |
| Saya, L | 1 |
| Trumbic, B | 1 |
| Gemzell Danielsson, K | 1 |
| Triebwasser, JE | 1 |
| Hesson, A | 1 |
| Langen, ES | 1 |
| Rifas-Shiman, SL | 2 |
| Cardenas, A | 1 |
| Hivert, MF | 1 |
| Tiemeier, H | 1 |
| Bertoldi, AD | 1 |
| Oken, E | 1 |
| Penfield, CA | 1 |
| McNulty, JA | 1 |
| Oakes, MC | 1 |
| Nageotte, MP | 1 |
| Xiong, T | 1 |
| Maheshwari, A | 1 |
| Neu, J | 1 |
| Ei-Saie, A | 1 |
| Pammi, M | 1 |
| Gómez de la F, CL | 1 |
| Novoa P, JM | 1 |
| Caviedes R, N | 1 |
| Balin, PDS | 1 |
| Jorge, BC | 1 |
| Leite, ARR | 1 |
| Borges, CS | 1 |
| Oba, E | 1 |
| Silva, EJR | 1 |
| de Barros, AL | 1 |
| Horta-Júnior, JAC | 1 |
| Arena, AC | 1 |
| Poljak, D | 1 |
| Chappelle, J | 1 |
| Bavis, RW | 1 |
| Song, MJ | 1 |
| Smachlo, JP | 1 |
| Hulse, A | 1 |
| Kenison, HR | 1 |
| Peralta, JN | 1 |
| Place, JT | 1 |
| Triebwasser, S | 1 |
| Warden, SE | 1 |
| McDonough, AB | 1 |
| Kemppainen, V | 1 |
| Mentula, M | 1 |
| Palkama, V | 1 |
| Heikinheimo, O | 1 |
| Colwill, AC | 1 |
| Alton, K | 1 |
| Bayer, LL | 1 |
| Jensen, JT | 1 |
| Garg, B | 1 |
| Beardsworth, K | 1 |
| Edelman, A | 2 |
| Wesselink, AK | 2 |
| Bresnick, KA | 1 |
| Hatch, EE | 2 |
| Rothman, KJ | 2 |
| Mikkelsen, EM | 2 |
| Wang, TR | 1 |
| Huybrechts, KF | 1 |
| Wise, LA | 2 |
| Wang, B | 1 |
| Yang, X | 1 |
| Yu, H | 1 |
| Man, X | 1 |
| Lamping, M | 1 |
| Gajus, J | 1 |
| Gonzalez, A | 1 |
| Nagendra, D | 1 |
| Sonalkar, S | 1 |
| Schurr, D | 1 |
| McAllister, A | 1 |
| Roe, AH | 1 |
| Shorter, JM | 1 |
| Sammel, MD | 1 |
| Schreiber, CA | 1 |
| Freud, LR | 1 |
| Wilkins-Haug, LE | 1 |
| Beroukhim, RS | 1 |
| LaFranchi, T | 1 |
| Phoon, CK | 1 |
| Glickstein, JS | 1 |
| Cumbermack, KM | 1 |
| Makhoul, M | 1 |
| Morris, SA | 1 |
| Sun, HY | 1 |
| Ferrer, Q | 1 |
| Pedra, SR | 1 |
| Tworetzky, W | 1 |
| El Manouni El Hassani, S | 1 |
| Niemarkt, HJ | 1 |
| Derikx, JPM | 1 |
| Berkhout, DJC | 1 |
| Ballón, AE | 1 |
| de Graaf, M | 1 |
| de Boode, WP | 1 |
| Cossey, V | 1 |
| Hulzebos, CV | 1 |
| van Kaam, AH | 1 |
| Kramer, BW | 1 |
| van Lingen, RA | 1 |
| Vijlbrief, DC | 1 |
| van Weissenbruch, MM | 1 |
| Benninga, MA | 1 |
| de Boer, NKH | 1 |
| de Meij, TGJ | 1 |
| Dafna, L | 1 |
| Herman, HG | 1 |
| Ben-Zvi, M | 1 |
| Bustan, M | 1 |
| Sasson, L | 1 |
| Bar, J | 1 |
| Kovo, M | 1 |
| Joye, S | 1 |
| McNamara, PJ | 1 |
| Giesinger, RE | 1 |
| Tolsa, JF | 1 |
| Sekarski, N | 1 |
| Hultzsch, S | 3 |
| Paulus, W | 1 |
| Padberg, S | 2 |
| Fietz, AK | 2 |
| Schaefer, C | 3 |
| Dathe, K | 2 |
| Mokhtari, NB | 1 |
| Saeed, H | 1 |
| Kawakita, T | 1 |
| Huang, JC | 1 |
| Iqbal, SN | 1 |
| Huang, X | 1 |
| Wang, F | 1 |
| Wang, K | 1 |
| Palmsten, K | 1 |
| Hulugalle, A | 1 |
| Bandoli, G | 1 |
| Kuo, GM | 1 |
| Ansari, S | 1 |
| Xu, R | 1 |
| Chambers, CD | 1 |
| Babayigit, A | 1 |
| Ozaydın, S | 1 |
| Cetinkaya, M | 1 |
| Sander, S | 1 |
| Petersen, TG | 1 |
| Liew, Z | 1 |
| Andersen, AN | 1 |
| Andersen, GL | 1 |
| Andersen, PK | 1 |
| Martinussen, T | 1 |
| Olsen, J | 3 |
| Rebordosa, C | 3 |
| Tollånes, MC | 1 |
| Uldall, P | 1 |
| Wilcox, AJ | 1 |
| Strandberg-Larsen, K | 1 |
| Leverrier-Penna, S | 1 |
| Mitchell, RT | 2 |
| Becker, E | 1 |
| Lecante, L | 1 |
| Ben Maamar, M | 2 |
| Homer, N | 1 |
| Lavoué, V | 2 |
| Kristensen, DM | 4 |
| Dejucq-Rainsford, N | 2 |
| Jégou, B | 4 |
| Mazaud-Guittot, S | 3 |
| Blue, NR | 1 |
| Murray-Krezan, C | 1 |
| Drake-Lavelle, S | 1 |
| Weinberg, D | 1 |
| Holbrook, BD | 1 |
| Katukuri, VR | 1 |
| Leeman, L | 2 |
| Mozurkewich, EL | 1 |
| Bigonnesse, E | 1 |
| Sicotte, B | 1 |
| Brochu, M | 1 |
| Pritchard, LW | 1 |
| Meixner, K | 1 |
| Meister, R | 1 |
| Hirshberg, JS | 1 |
| Cahill, AG | 1 |
| Zaretsky, M | 1 |
| Wood, C | 1 |
| Nivens, T | 1 |
| McLaughlin, G | 1 |
| Zuk, J | 1 |
| Pan, Z | 1 |
| Chow, F | 1 |
| Sellem, E | 1 |
| Badiou, S | 1 |
| Sutra, T | 1 |
| Ndubisi, C | 1 |
| Danvers, A | 1 |
| Gold, MA | 1 |
| Morrow, L | 1 |
| Westhoff, CL | 2 |
| Stritzke, A | 1 |
| Soraisham, AS | 1 |
| McNairn, AJ | 1 |
| Chuang, CH | 1 |
| Bloom, JC | 1 |
| Wallace, MD | 1 |
| Schimenti, JC | 1 |
| Araujo, M | 1 |
| Hurault-Delarue, C | 2 |
| Bouilhac, C | 1 |
| Petiot, D | 1 |
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| Vayssière, C | 1 |
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| Montastruc, JL | 1 |
| Damase-Michel, C | 2 |
| Lacroix, I | 1 |
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| Falcao, AC | 1 |
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| Knibbe, CAJ | 1 |
| Krekels, EHJ | 1 |
| Nezvalová-Henriksen, K | 2 |
| Spigset, O | 2 |
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| Raymond, EG | 1 |
| Weaver, MA | 1 |
| Louie, KS | 1 |
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| Lichtenberg, ES | 1 |
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| Arnesen, M | 1 |
| Oulmaati, A | 1 |
| Hays, S | 1 |
| Ben Said, M | 1 |
| Maucort-Boulch, D | 1 |
| Jordan, I | 1 |
| Picaud, JC | 1 |
| Youn, YA | 1 |
| Moon, CJ | 1 |
| Kim, SY | 1 |
| Lee, JY | 1 |
| Sung, IK | 1 |
| Bueters, RR | 1 |
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| Kent, AL | 3 |
| Koina, ME | 3 |
| Gubhaju, L | 2 |
| Cullen-McEwen, LA | 1 |
| Bertram, JF | 2 |
| Lynnhtun, J | 1 |
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| Falk, MC | 3 |
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| Oncel, MY | 1 |
| Erdeve, O | 1 |
| Sordillo, JE | 1 |
| Scirica, CV | 1 |
| Gillman, MW | 1 |
| Bunyavanich, S | 1 |
| Camargo, CA | 1 |
| Weiss, ST | 1 |
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| Litonjua, AA | 1 |
| Singh, RH | 1 |
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| Pereda, B | 1 |
| Ogburn, T | 1 |
| Shaheen, SO | 1 |
| Derry, CJ | 2 |
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| Moore, RA | 2 |
| Daniel, S | 1 |
| Koren, G | 1 |
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| Levy, A | 1 |
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| Bertsche, T | 1 |
| Borte, M | 1 |
| von Bergen, M | 1 |
| Wissenbach, DK | 1 |
| Bohio, R | 1 |
| Brohi, ZP | 1 |
| Bohio, F | 1 |
| Schmidt, JJ | 1 |
| Ramazan, L | 1 |
| Bockemeyer, C | 1 |
| Günter, HH | 2 |
| Martens-Lobenhoffer, J | 1 |
| Ganzenmüller, T | 1 |
| Bode-Böger, SM | 1 |
| Kielstein, JT | 1 |
| Terada, KY | 1 |
| Ahn, HJ | 1 |
| Kessel, B | 1 |
| Philippot, G | 1 |
| Nyberg, F | 1 |
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| Fredriksson, A | 1 |
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| Maxwell, LE | 2 |
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| Ordean, A | 1 |
| Selby, P | 1 |
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| Ashdown, H | 1 |
| Luheshi, GN | 1 |
| Boksa, P | 1 |
| Cansino, C | 1 |
| Burke, A | 1 |
| Jamshidi, R | 1 |
| Jensen, MS | 2 |
| Thulstrup, AM | 2 |
| Toft, G | 2 |
| Sørensen, HT | 2 |
| Bonde, JP | 2 |
| Henriksen, TB | 2 |
| Durrmeyer, X | 1 |
| Hovhannisyan, S | 1 |
| Médard, Y | 1 |
| Jacqz-Aigrain, E | 1 |
| Decobert, F | 1 |
| Barre, J | 1 |
| Alberti, C | 1 |
| Aujard, Y | 1 |
| Danan, C | 1 |
| Baud, O | 1 |
| Hass, U | 1 |
| Lottrup, G | 1 |
| Jacobsen, PR | 1 |
| Boberg, J | 1 |
| Petersen, JH | 1 |
| Toppari, J | 1 |
| Jensen, TK | 1 |
| Brunak, S | 1 |
| Skakkebaek, NE | 1 |
| Nellemann, C | 1 |
| Leffers, H | 1 |
| Waleh, N | 1 |
| McCurnin, DC | 1 |
| Yoder, BA | 2 |
| Shaul, PW | 1 |
| Clyman, RI | 2 |
| Vieux, R | 1 |
| Fresson, J | 1 |
| Guillemin, F | 1 |
| Hascoet, JM | 1 |
| Micu, MC | 1 |
| Micu, R | 1 |
| Ostensen, M | 1 |
| Hunt, JC | 1 |
| Schneider, C | 1 |
| Menticoglou, S | 1 |
| Del Bigio, MR | 1 |
| Lyons, TR | 1 |
| O'Brien, J | 1 |
| Borges, VF | 1 |
| Conklin, MW | 1 |
| Keely, PJ | 1 |
| Eliceiri, KW | 1 |
| Marusyk, A | 1 |
| Tan, AC | 1 |
| Schedin, P | 1 |
| Bollag, L | 1 |
| Richebe, P | 1 |
| Ortner, C | 1 |
| Landau, R | 1 |
| Guerrero, JM | 1 |
| Castaño, PM | 1 |
| Schmidt, EO | 1 |
| Rosario, L | 1 |
| Avraham, S | 1 |
| Gat, I | 1 |
| Duvdevani, NR | 1 |
| Haas, J | 1 |
| Frenkel, Y | 1 |
| Seidman, DS | 1 |
| Sutherland, MR | 1 |
| McCurnin, D | 1 |
| Seidner, S | 1 |
| Black, MJ | 1 |
| Hammerman, C | 1 |
| Bin-Nun, A | 1 |
| Kaplan, M | 1 |
| Bhatt, M | 1 |
| Petrova, A | 1 |
| Mehta, R | 1 |
| Selbst, SM | 1 |
| Osterhoudt, K | 1 |
| Bardage, C | 1 |
| Westerlund, T | 1 |
| Barzi, S | 1 |
| Bernsten, C | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prophylactic Pregabalin to Decrease Pain During Medical Abortion: a Randomized Controlled Trial[NCT02782169] | Phase 4 | 110 participants (Actual) | Interventional | 2015-06-30 | Completed | ||
| PAIN CONTROL IN FIRST TRIMESTER MEDICAL ABORTION: A Randomized Trial[NCT01457521] | Phase 4 | 250 participants (Actual) | Interventional | 2011-10-31 | Completed | ||
| The Effect of Prophylactic Ibuprofen Versus Placebo on Pain Relief and Success Rates of Medical Abortion: A Double-blind Randomized Placebo Controlled Study[NCT00997074] | Phase 3 | 61 participants (Actual) | Interventional | 2009-10-31 | Completed | ||
| A Randomized Controlled Trial on the Effects of NSAIDs on Postpartum Blood Pressure in Patients Hypertensive Disorders of Pregnancy[NCT03011567] | 202 participants (Actual) | Interventional | 2017-01-31 | Completed | |||
| Post-operative Pain Control With Acetaminophen and Ibuprofen After Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: a Prospective Study.[NCT05287217] | 60 participants (Anticipated) | Interventional | 2022-07-29 | Not yet recruiting | |||
| Cannabinoid Analgesia for Medical Abortion: A Randomized Controlled Trial[NCT03604341] | Phase 4 | 72 participants (Actual) | Interventional | 2018-11-01 | Completed | ||
| Comparing Protocols for Analgesia Following Elective Cesarean Section[NCT03622489] | Phase 4 | 120 participants (Anticipated) | Interventional | 2017-03-01 | Recruiting | ||
| Educational Video on Pain Management and Subsequent Opioid Use After Cesarean Delivery[NCT03959969] | 48 participants (Actual) | Interventional | 2019-07-17 | Completed | |||
| The Copenhagen Analgesic Study[NCT04369222] | 600 participants (Anticipated) | Observational | 2020-03-01 | Recruiting | |||
| Auriculotherapy as an Adjunct for Pain Management During Medication Abortion: a Randomized, Double-blinded, Three-arm Trial[NCT03900728] | 138 participants (Actual) | Interventional | 2019-04-01 | Completed | |||
| Auriculotherapy as an Adjunct for Pain Management During First Trimester Vacuum Aspiration Abortion: a Randomized, Double-blinded, Three Arm Trial[NCT03896022] | 177 participants (Actual) | Interventional | 2019-03-28 | Completed | |||
| Auricular Acupuncture as Adjunct for Pain Management During First Trimester Uterine Aspiration.[NCT03391986] | 153 participants (Actual) | Interventional | 2017-09-09 | Completed | |||
| Nitrous Oxide for Pain Management of First Trimester Surgical Abortion[NCT02096575] | 140 participants (Actual) | Interventional | 2012-08-31 | Completed | |||
| Effect of Non-steroidal Anti-inflammatory Use on Blood Pressure in Women With Hypertensive Disorders of Pregnancy: A Randomized Open Label Trial[NCT03824119] | Phase 4 | 200 participants (Anticipated) | Interventional | 2018-12-11 | Recruiting | ||
| Paracervical Block for Pain Control During Osmotic Dilator Placement: a Randomized Controlled Trial[NCT02354092] | 14 participants (Actual) | Interventional | 2015-04-02 | Terminated | |||
| Paracervical Block With Ketorolac and Lidocaine in First Trimester Surgical Abortions[NCT00617097] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
| Music to Reduce Patient Reported Pain During Intrauterine Device (IUD) Placement in the Office[NCT05068245] | 96 participants (Actual) | Interventional | 2020-08-28 | Completed | |||
| Music as an Auxiliary Analgesic and Anxiolytic During First Trimester Abortion[NCT01013363] | 106 participants (Actual) | Interventional | 2009-09-30 | Completed | |||
| Paracetamol (Acetaminophen) for Closure of PDA in Preterm Infants[NCT01755728] | Phase 3 | 19 participants (Actual) | Interventional | 2013-01-01 | Completed | ||
| An Evaluation of Hydrocodone/Acetaminophen for Pain Control in First Trimester Surgical Abortion[NCT01330459] | Phase 4 | 121 participants (Actual) | Interventional | 2011-02-28 | Completed | ||
| An Evaluation of the Paracervical Block for Pain Control in First Trimester Surgical Abortion[NCT01094366] | Phase 4 | 121 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| Postplacental Intrauterine Device Insertion: A Mixed Methods Assessment of Women's Experience[NCT02312726] | 135 participants (Actual) | Observational | 2013-11-30 | Completed | |||
| Pain Control for Intrauterine Device Placement: A Randomized Controlled Trial of Paracervical Block[NCT02219308] | 67 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| Randomized Controlled Trial of Cervical Lidocaine for Intrauterine Device Insertion Pain[NCT01411995] | 200 participants (Actual) | Interventional | 2011-08-31 | Completed | |||
| Study of Pain Control With Hormonal IUS Insertion (SOPHI Study)[NCT02352714] | Phase 4 | 98 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| Effect of Adding Vaginal Isosorbide Mononitrate to Misoprostol Prior to Intrauterine Device Insertion in Women Delivered Only by Elective Cesarean Section: a Randomized Double-blind Controlled Clinical Trial[NCT03587077] | 113 participants (Anticipated) | Interventional | 2018-09-30 | Not yet recruiting | |||
| Intravenous Versus Oral Acetaminophen for Postoperative Pain Control After Cesarean Delivery[NCT02487303] | 148 participants (Actual) | Interventional | 2015-03-17 | Completed | |||
| Buffered Lidocaine for Paracervical Block to Decrease Injection Pain During First Trimester Uterine Aspirations[NCT03107754] | Phase 4 | 98 participants (Actual) | Interventional | 2017-05-15 | Completed | ||
| Dextromethorphan as a Novel Non-opioid Adjunctive Agent for Pain Control in Medication Abortion: a Randomized Controlled Trial[NCT03480009] | Phase 3 | 156 participants (Actual) | Interventional | 2018-07-28 | Completed | ||
| Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)[NCT02409680] | 11,976 participants (Actual) | Interventional | 2016-03-23 | Completed | |||
| Liberal Versus Restrictive Platelet Transfusion for Treatment of Hemodynamically Significant Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates- A Randomized Open Label, Controlled Trial[NCT03022253] | Phase 3 | 44 participants (Anticipated) | Interventional | 2016-03-31 | Completed | ||
| Evaluation of the Efficacy of the Photobiomodulation on the Pelvi-perineal Pain in Patients in Immediate Post-partum Situation[NCT04896034] | 677 participants (Anticipated) | Interventional | 2021-05-06 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
reported on an 11-point numerical rating scale (NRS 0-10) where 0 indicates no pain and 10 indicates the most severe pain (NCT02782169)
Timeframe: Over 72 hours (measured at 0, 2, 6, 12, 24, and 72 hours)
| Intervention | units on a scale (Mean) |
|---|---|
| Pregabalin | 5.0 |
| Placebo | 5.5 |
summed number of tablets used by each participant over the 72 hour study period (NCT02782169)
Timeframe: Over 72 hours (measured at 0, 2, 6, 12, 24, and 72 hours)
| Intervention | tablets (Median) |
|---|---|
| Pregabalin | 1 |
| Placebo | 2 |
summed number of tablets used by each participant over the 72 hour study period (NCT02782169)
Timeframe: Over 72 hours (measured at 0, 2, 6, 12, 24, and 72 hours)
| Intervention | tablets (Median) |
|---|---|
| Pregabalin | 0 |
| Placebo | 0.5 |
A participant was included once if they ever reported a symptom during the 72 hour study period, not reflective of how long the symptom lasted. These were all commonly reported side effects during previous research on medication abortions and commonly reported side effects of pregabalin, so they were not included as adverse events. (NCT02782169)
Timeframe: Over 72 hours (measured at 0, 2, 6, 12, 24, and 72 hours)
| Intervention | participants (Number) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Nausea | Vomiting | Sleepiness | Dizziness | Headache | Blurred Vision | Diarrhea | Constipation | Dry Mouth | |
| Placebo | 42 | 30 | 39 | 26 | 17 | 7 | 29 | 15 | 25 |
| Pregabalin | 43 | 28 | 47 | 45 | 28 | 15 | 28 | 6 | 22 |
Participant pain was assessed using an 11-point Visual Analog Scale for Pain. Scores ranged from 0 (no pain) to 10 (worst pain possible) (NCT01457521)
Timeframe: 1-2 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Prophylactic | 7.1 |
| Therapeutic | 7.3 |
Women will text responds to surveys within 24 hours after misoprostol administration indicating their maximum self-reported pain using an 11-point numeric rating scale (NRS 0-10) where 0=no pain and 10=worst possible pain. (NCT03604341)
Timeframe: 24 hours after misoprostol administration
| Intervention | score on a scale (Median) |
|---|---|
| Gestational Age up to 10w0d - Dronabinol | 7 |
| Gestational Age up to 10w0d - Placebo | 7 |
Self-assessed maximum anxiety reported using a 0-100 mm visual analog scale, where 100 signifies maximum anxiety. (NCT03900728)
Timeframe: Auriculotherapy is applied on the day of mifepristone. Participants take misoprostol 1-3 days later. Anxiety scores are recorded following misoprostol at 8pm x 4 days (selecting the highest of 4 for analysis).
| Intervention | score on a scale (Median) |
|---|---|
| Auriculotherapy With Needles (Acupuncture) + Usual Care | 45 |
| Auriculotherapy With Gold Beads (Acupressure) + Usual Care | 10 |
| Placebo Group + Usual Care | 30 |
Self-assessed maximum pain reported using a 0-100 mm visual analog scale (VAS), where 100 signifies maximum pain. (NCT03900728)
Timeframe: Auriculotherapy is applied on the day of mifepristone. Participants take misoprostol 1-3 days later. Pain scores are recorded following misoprostol at 8pm x 4 days (selecting the highest of the 4 for analysis).
| Intervention | score on a scale (Median) |
|---|---|
| Auriculotherapy With Needles (Acupuncture) + Usual Care | 75 |
| Auriculotherapy With Gold Beads (Acupressure) + Usual Care | 60 |
| Placebo Group + Usual Care | 55 |
Self-assessed maximum anxiety reported using a 0-100 mm visual analog scale, where 100 signifies maximum anxiety. To measure anxiety during aspiration abortion. (NCT03896022)
Timeframe: Immediately following the aspiration abortion procedure (approximately 10 minutes)
| Intervention | score on a scale (Median) |
|---|---|
| Auriculotherapy - Acupressure With Gold Beads | 26 |
| Auriculotherapy - Acupuncture With Pyonex Needles | 28 |
| Placebo Group | 21 |
Self-assessed maximum pain reported using a 0-100mm visual analog scale, where 100 signifies maximum pain. To measure pain experienced during aspiration abortion. (NCT03896022)
Timeframe: Immediately following the aspiration abortion procedure (approximately 10 minutes)
| Intervention | score on a scale (Median) |
|---|---|
| Auriculotherapy - Acupressure With Gold Beads | 50 |
| Placebo Group | 47.5 |
Self-assessed maximum pain reported using a 0-100mm visual analog scale, where 100 signifies maximum pain. To measure pain experienced during aspiration abortion. (NCT03896022)
Timeframe: Immediately following the aspiration abortion procedure (approximately 10 minutes)
| Intervention | score on a scale (Median) |
|---|---|
| Auriculotherapy - Acupuncture With Pyonex Needles | 55 |
| Placebo Group | 47.5 |
Measure effectiveness of placebo as an adjunct to ibuprofen and paracervical block for pain control during uterine aspiration by comparing the maximum pain score; as measured by VAS between women randomized to receive placebo adhesives and routine care controls - using a 100 mm visual analog scale (VAS-P) (anchors: 0 mm = no pain, 100 mm = worst pain in my life). (NCT03391986)
Timeframe: prior to the procedure (baseline), at the completion of the procedure (approximately 10 minutes later)
| Intervention | score on a scale (Mean) |
|---|---|
| Placebo Adhesives | 70.0 |
| Routine Care | 71.0 |
Using a satisfaction survey (investigator-developed, 6 questions, each question is graded on a scale of 1-5, 1 being very poor and 5 being very good) to measure effectiveness of auricular acupuncture for improving satisfaction. (NCT03391986)
Timeframe: at the completion of the procedure (approximately 5-10 minutes)
| Intervention | percentage of participants (Number) |
|---|---|
| Pyonex Needles | 94 |
| Routine Care | 76 |
Measure effectiveness of auricular acupuncture as an adjunct to ibuprofen and paracervical block for pain control during first trimester uterine aspiration by comparing the maximum pain score; as measured by VAS between women randomized to receive auricular acupuncture and routine care controls - using a 100 mm visual analog scale (VAS-P) (anchors: 0 mm = no pain, 100 mm = worst pain in my life). The VAS has no sub-scales. (NCT03391986)
Timeframe: at the completion of the procedure (approximately 10 minutes later)
| Intervention | score on a scale (Mean) |
|---|---|
| Pyonex Needles | 39.5 |
| Routine Care | 71.0 |
Quantitative assessment of pain management. Pain was assessed using the Visual Analog Scale (VAS). 0 = no pain, 100 = maximum pain (NCT02096575)
Timeframe: Visual analog scale for satisfaction administered on average within 20 minutes after procedure completion.
| Intervention | units on a scale (Mean) |
|---|---|
| Nitrous Oxide Administration | 69.3382 |
| Standard Care Group | 61.5373 |
"The primary outcome of this study is to evaluate the difference in mean maximum pain experienced during the procedure between groups as assessed 5 minutes after the procedure is completed.~Pain was assessed using the Visual Analog Scale (VAS). 0 = no pain, 100 = maximum pain" (NCT02096575)
Timeframe: Mean maximum pain experienced during the procedure and assessed 5 minutes after the procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Nitrous Oxide Administration | 54.37 |
| Standard Care Group | 60.48 |
A quantitative assessment of post-procedure pain. Pain was assessed using the Visual Analog Scale (VAS). 0 = no pain, 100 = maximum pain (NCT02096575)
Timeframe: Visual analog scale administered on average 20 minutes after procedure completed
| Intervention | units on a scale (Mean) |
|---|---|
| Nitrous Oxide Administration | 26.68 |
| Standard Care Group | 25.96 |
A quantitative assessment of pain prior to the procedure. Pain was assessed using the Visual Analog Scale (VAS). 0 = no pain, 100 = maximum pain (NCT02096575)
Timeframe: Baseline pain assessment on average within 30 minutes before procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Nitrous Oxide Administration | 4.7426 |
| Standard Care Group | 4.4388 |
Anticipated pain is assessed before the procedure. Pain was assessed using the Visual Analog Scale (VAS). 0 = no pain, 100 = maximum pain (NCT02096575)
Timeframe: Anticipated pain assessed on average within 30 minutes before procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Nitrous Oxide Administration | 56.1544 |
| Standard Care Group | 50.3104 |
"Measure of distance (mm) from the left (no pain) on the 100-mm visual analog scale (VAS - reflecting magnitude of pain) recorded at time immediately after osmotic dilator placement. 0 mm=No Pain and 100 mm= worst possible pain. A higher score indicates a higher level of pain." (NCT02354092)
Timeframe: Within 5 minutes of PCB or sham procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Sham Group | 46 |
| Paracervical Block Group | 32 |
"Measure of distance (mm) from the left (no pain) on the 100-mm visual analog scale (VAS - reflecting magnitude of pain) recorded 15 minutes after osmotic dilator placement. mm=No Pain and 100 mm= worst possible pain. A higher mean score indicates a higher level of pain experienced at this time point." (NCT02354092)
Timeframe: 15 minutes after dilator placement
| Intervention | units on a scale (Mean) |
|---|---|
| Sham Group | 42 |
| Paracervical Block Group | 35 |
"Measure of distance (mm) from the left (no pain) on the 100-mm visual analog scale (VAS - reflecting magnitude of pain) recorded at time immediately after last injection for paracervical block OR script for sham injection. 0 mm=No Pain and 100 mm= worst possible pain. A higher score indicates a higher level of pain." (NCT02354092)
Timeframe: Within 5 minutes after baseline
| Intervention | units on a scale (Mean) |
|---|---|
| Sham Group | 19 |
| Paracervical Block Group | 39 |
"Measure of distance (mm) from the left (no pain) on the 100-mm visual analog scale (VAS - reflecting magnitude of pain) of pain recorded at baseline prior to the paracervical block or sham block procedure. 0 mm=No Pain and 100 mm= worst possible pain. A higher score indicates a higher level of pain." (NCT02354092)
Timeframe: Baseline, just prior to PCB or sham procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Sham Group | 4 |
| Paracervical Block Group | 19 |
fever, chills, vomiting, heavy bleeding/clots (collected without regard to the specific event) (NCT00617097)
Timeframe: end of study (upon discharge from facility after procedure)
| Intervention | participants (Number) |
|---|---|
| Paracervical Block With Lidocaine | 3 |
| Paracervical Block With Ketorolac and Lidocaine | 0 |
100-mm Visual Analogue Scale -- minimum: 0 mm (lower satisfaction), maximum: 100 mm (greater satisfaction) (NCT00617097)
Timeframe: end of study (prior to clinic discharge)
| Intervention | mm (Mean) |
|---|---|
| Paracervical Block With Lidocaine | 62.9 |
| Paracervical Block With Ketorolac and Lidocaine | 63.6 |
(NCT00617097)
Timeframe: end of study
| Intervention | participants (Number) | |
|---|---|---|
| minor | serious | |
| Paracervical Block With Ketorolac and Lidocaine | 1 | 2 |
| Paracervical Block With Lidocaine | 1 | 0 |
"100-mm Visual Analogue Scale (VAS) during specific time intervals of D&C procedure: minimum: 0 mm (less pain); maximum: 100 mm (more pain)~Time intervals include: basline expected level of pain during procedure, after speculum insertion, at paracervical block injection, after dilation, end of procedure, and 30 minutes after procedure." (NCT00617097)
Timeframe: Baseline, Speculum Insertion, at Paracervical block injection, After dilation, End of procedure, 30 minutes after procedure
| Intervention | mm (Mean) | |||||
|---|---|---|---|---|---|---|
| expected level of pain during procedure | after speculum insertion | during paracervical block administration | after cervical dilation | immediately after procedure | 30 min after procedure | |
| Paracervical Block With Ketorolac and Lidocaine | 51.7 | 32.7 | 46.0 | 59.8 | 64.3 | 17.6 |
| Paracervical Block With Lidocaine | 52.2 | 33.6 | 50.8 | 74.8 | 61.5 | 21.8 |
To assess need for additional intraoperative and/or postoperative pain medication (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
| Intervention | Participants (Count of Participants) |
|---|---|
| Hydrocodone/Acetaminophen | 0 |
| Placebo | 0 |
To determine whether HC/APAP, given in addition to a standard regimen of ibuprofen, lorazepam, and PCB, affects patient pain perception at the time of uterine aspiration, as measured by distance (mm) from the left of the 100 mm visual analog scale (VAS). The number 0 indicates no pain, and 100 indicates worst pain imaginable. (NCT01330459)
Timeframe: At time of uterine aspiration (baseline)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 65.7 |
| Placebo | 63.1 |
Distance (mm) from the left of the 100 mm VAS scale (VAS anchors: 0 = none, 100 mm = worst imaginable) recorded after cervical dilation (NCT01330459)
Timeframe: During procedure (approximately 45-90 min after hydrocodone/acetaminophen or placebo, and within 5 minutes of procedure starting)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 47.2 |
| Placebo | 43.9 |
To assess whether HC/APAP is associated with nausea, measured on the 100 mm VAS, recorded 30 minutes postoperatively. VAS anchors: 0 indicates no pain, and 100 indicates worst pain imaginable. (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 19.4 |
| Placebo | 11.4 |
Distance (mm) from the left of the 100 mm VAS (VAS anchors: 0 = unsatisfied, 100 mm = very satisfied) recorded 30 minutes after completion of the procedure. (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 74.8 |
| Placebo | 67.3 |
A semi-structured interview guide(available in both English and Spanish) which was developed in consultation with an expert in qualitative methodology at the UNM Clinical & Translational Science Center (CTSC), and UNMH family planning experts, will be administered to all participants. The interview will incorporate the following domains of women's perceptions of the postplacental IUD insertion experience: decisional influence, experience during the procedure, decisional regret, prior knowledge/ awareness of the method and postpartum contraception in general. The interview will conclude with an overall patient satisfaction score measured on a five-point Likert scale: 1 = very dissatisfied, 2 = somewhat dissatisfied, 3 = neutral, 4 = somewhat satisfied, 5 = very satisfied. (NCT02312726)
Timeframe: Within 24-48 hours after vaginal delivery, prior to hospital discharge
| Intervention | participants (Number) | ||||
|---|---|---|---|---|---|
| Very Satified | Satisfied | Neutral | Dissatisfied | Very Dissatisfied | |
| Epidural Group | 12 | 0 | 0 | 0 | 0 |
| Non Epidural Group | 7 | 2 | 0 | 0 | 0 |
This is a 4-item ordinal pain scale which has been used for pain level assessment. When prompted, patients will be asked to indicate which level of pain most accurately represents their pain level; 0 = No pain, 1 = Mild pain, 2 = Moderate pain, 3 = Severe pain. (NCT02312726)
Timeframe: Immediately prior to and within 5 minutes after IUD insertion following vaginal delivery. Women who undergo a postpartum interview will be asked to perform a recal VRS pain assessment
| Intervention | participants (Number) | |||||
|---|---|---|---|---|---|---|
| No Pain or Mild Pain before IUD placement | No Pain or Mild Pain during IUD placement | No Pain or Mild Pain at recall | Moderate Pain or Severe Pain before IUD placement | Moderate Pain or Severe Pain during IUD placement | Moderate Pain or Severe Pain at recall | |
| Epidural Group | 34 | 32 | 12 | 2 | 4 | 0 |
| Non Epidural Group | 15 | 16 | 6 | 15 | 14 | 3 |
This is a validated instrument used extensively in the assessment of acute pain. When prompted, patients will be asked to mark the continuous 100 mm VAS line at the point which most accurately represents their pain level; 0 = no pain, 100 = pain as bad as it could be. (NCT02312726)
Timeframe: Immediately prior to and within 5 minutes after IUD insertion following vaginal delivery; women who undergo a postpartum interview will be asked to perform a recall VAS pain assessment
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Pre-insertion | Procedure | Recall | |
| Epidural Group | 10.6 | 10.9 | 5.4 |
| Non Epidural Group | 35.3 | 41.4 | 28.6 |
The provider who inserts the IUD will be asked to complete a 4-item Likert scale rating perceived difficultly of insertion: 1 = easy; 2 = somewhat easy; 3 = somewhat difficult, 4 = difficult. (NCT02312726)
Timeframe: Within 5 minutes following postpartum IUD insertion
| Intervention | participants (Number) | ||||
|---|---|---|---|---|---|
| Easy | Somewhat easy | Somewhat difficult | Difficult | Unanswered | |
| Epidural Group | 19 | 16 | 3 | 0 | 0 |
| Non Epidural Group | 15 | 11 | 3 | 0 | 1 |
Distance (mm) from the left of the 100-mm visual analog scale (reflecting magnitude of pain) recorded at time of IUD Placement. Scale range is from 0mm (no pain) to 100mm (worst pain possible). A lower score (less pain) is considered a better outcome. (NCT02219308)
Timeframe: Moment of IUD insertion
| Intervention | mm (Median) |
|---|---|
| No Paracervical Block (Sham PCB) | 54 |
| Paracervical Block (PCB) | 33 |
Distance (mm) from the left of the 100-mm visual analog scale of pain at various time points. Scale range is 0mm (no pain) to 100mm (worst pain possible). Lower scores are considered better outcomes. (NCT02219308)
Timeframe: Anticipation of procedure through 5 minutes after IUD placement
| Intervention | mm (Median) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Anticipated Pain | Baseline Pain | Speculum Insertion | Capped Needle or PCB | Tenaculum placement | Uterine Sounding | IUD placement | 5 mins after IUD placement | Overall pain | |
| No Paracervical Block (Sham PCB) | 51 | 0 | 6 | 8 | 10 | 47 | 54 | 27 | 51 |
| Paracervical Block (PCB) | 58 | 0 | 10 | 30 | 15 | 30 | 33 | 12 | 30 |
"Using a visual analog scale, women will report their level of pain pre-procedure, after tenaculum placement, and post-procedure (following IUD insertion).The entirety of the procedure should last no more than 5-10 minutes. The pain score is assessed at the 3 timepoints within that 10 minute window. No additional followup is required.~Range: 0-10 (0= no pain, 10=worst pain)" (NCT01411995)
Timeframe: Immediately following IUD insertion
| Intervention | units on visual analog scale (Median) |
|---|---|
| 2% Lidocaine Gel | 5 |
| Water Based Lubricant | 6 |
Cumulative opiate consumption (IV morphine equivalents) (NCT02487303)
Timeframe: 24 hours
| Intervention | mg (Mean) |
|---|---|
| Acetaminophen Intravenous | 2.9 |
| Acetaminophen Oral | 3.8 |
| No Acetaminophen | 5.7 |
Time patient meets discharge criteria will be recorded (NCT02487303)
Timeframe: 24 hours postoperative
| Intervention | hours (Mean) |
|---|---|
| Acetaminophen Intravenous | 48.4 |
| Acetaminophen Oral | 48.6 |
| No Acetaminophen | 50.5 |
Time to first opiate pain medicine requested by patient (NCT02487303)
Timeframe: 48 hours
| Intervention | hours (Mean) |
|---|---|
| Acetaminophen Intravenous | 25.3 |
| Acetaminophen Oral | 24.0 |
| No Acetaminophen | 21.3 |
"Visual Analog Scale (VAS) pain assessment with ambulation. The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between no pain and worst pain. For pain intensity, the scale is most commonly anchored by no pain (score of 0) and pain as bad as it could be or worst imaginable pain (score of 100 [100-mm scale]) ." (NCT02487303)
Timeframe: 24 hours
| Intervention | units on a scale (Mean) |
|---|---|
| Acetaminophen Intravenous | 37.8 |
| Acetaminophen Oral | 44.3 |
| No Acetaminophen | 50.8 |
For the primary outcome, pain immediately after paracervical block injection was measured by a scale. The scale used was the 100-mm visual analog scale. The minimum score was 0 and the maximum score was 100. Higher numbers indicate worse pain. (NCT03107754)
Timeframe: Immediately after injection of the paracervical block
| Intervention | units on a scale (Median) |
|---|---|
| Standard Paracervical Block | 44.5 |
| Buffered Lidocaine Paracervical Block | 30 |
Pain scores were measured at multiple points throughout the procedure. Pain scores were measured using a 100 mm visual analog scale with 0 being no pain and 100 being the worst pain ever. (NCT03107754)
Timeframe: Immediately after speculum placement, cervical dilation, uterine aspiration
| Intervention | units on a scale (Median) | ||
|---|---|---|---|
| After insertion of speculum | After cervical dilation | After uterine aspiration | |
| Buffered Lidocaine Paracervical Block | 17 | 55 | 69 |
| Standard Paracervical Block | 13 | 60.06 | 67.5 |
"Marginal mean pain scores via Numeric Rating Scale (NRS-11) over 24 hours. The scale is from 0 to 10, where 0 represents no pain and 10 represents the worst pain possible." (NCT03480009)
Timeframe: Marginal mean pain scores over 24 hours
| Intervention | score on a scale (NRS-11) (Mean) |
|---|---|
| Dextromethorphan, Opted for Narcotic Prescription | 2.93 |
| Placebo, Opted for Narcotic Prescription | 2.96 |
| Dextromethorphan, Declined Narcotic Prescription | 2.70 |
| Placebo, Declined Narcotic Prescription | 2.41 |
"Self-reported pain measurement via text-messaging system during first 24 hours after misoprostol administration. The scale is from 0 to 10, where 0 represents no pain and 10 represents the worst pain possible." (NCT03480009)
Timeframe: Over 24 hours starting from misoprostol administration
| Intervention | score on a scale (Median) |
|---|---|
| Dextromethorphan, Opted for Narcotic Prescription | 8.0 |
| Placebo, Opted for Narcotic Prescription | 7.0 |
| Dextromethorphan, Declined Narcotic Prescription | 7.5 |
| Placebo, Declined Narcotic Prescription | 6.5 |
Analgesic usage by study arm for women who received dextromethorphan vs. placebo as adjunct to routine pain management during medication abortion; missing data are for participants who did not take the specified pain medication. (NCT03480009)
Timeframe: Over 24 hours
| Intervention | mg (Median) | |
|---|---|---|
| ibuprofen | 9acetaminophen | |
| Dextromethorphan, Declined Narcotic Prescription | 800 | 800 |
Analgesic usage by study arm for women who received dextromethorphan vs. placebo as adjunct to routine pain management during medication abortion; missing data are for participants who did not take the specified pain medication. (NCT03480009)
Timeframe: Over 24 hours
| Intervention | mg (Median) | ||
|---|---|---|---|
| ibuprofen | 9acetaminophen | oxycodone | |
| Dextromethorphan, Opted for Narcotic Prescription | 800 | 1000 | 10 |
| Placebo, Declined Narcotic Prescription | 1000 | 975 | 15 |
| Placebo, Opted for Narcotic Prescription | 600 | 1300 | 15 |
- Early preterm delivery (<34 weeks) (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 189 |
| Placebo Arm | 230 |
- Birth weight <2500g (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 1078 |
| Placebo Arm | 1153 |
- Birth weight <1500g (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 78 |
| Placebo Arm | 101 |
- Incidence of Fetal Loss (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 303 |
| Placebo Arm | 353 |
- Incidence of Spontaneous Abortion (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 134 |
| Placebo Arm | 152 |
- Incidence of All stillbirth (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 141 |
| Placebo Arm | 166 |
- Incidence of Medical Termination of Pregnancy (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 42 |
| Placebo Arm | 30 |
- Hypertensive disorders of pregnancy is defined by the characterization of evidence of a hypertensive disorder, including either preeclampsia or eclampsia occurring during the pregnancy. (NCT02409680)
Timeframe: Evidence of hypertensive disorder during the pregnancy (prior to delivery/birth)
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 352 |
| Placebo Arm | 325 |
- Incidence of Perinatal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 264 |
| Placebo Arm | 309 |
The primary outcome of this study is incidence of preterm birth, which will be defined as delivery at or after 20 0/7 weeks and prior to 37 0/7 weeks. This will be determined based on actual date of delivery in comparison to the projected estimated due date (EDD), independent of whether or not the preterm delivery is indicated or spontaneous. (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 668 |
| Placebo Arm | 754 |
- Small for gestational age (SGA) as defined by the INTERGROWTH-21st standard (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 1506 |
| Placebo Arm | 1564 |
- Vaginal bleeding (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 214 |
| Placebo Arm | 246 |
- Antepartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 26 |
| Placebo Arm | 25 |
- Postpartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 54 |
| Placebo Arm | 43 |
- Incidence of Maternal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 9 |
| Placebo Arm | 12 |
- Incidence of Late Abortion (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 23 |
| Placebo Arm | 30 |
Hemoglobin < 7.0 gm/dl at 26-30 weeks gestation or a drop of 3.5+ gm/dl from screening to 26-30 weeks gestation (NCT02409680)
Timeframe: At enrollment, 4 weeks post enrollment, and 26-30 weeks GA.
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 290 |
| Placebo Arm | 333 |
Early preterm delivery (<34 weeks) and hypertensive disorders (i.e.: preeclampsia) (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 8 |
| Placebo Arm | 21 |
20 reviews available for ibuprofen and Pregnancy
| Article | Year |
|---|---|
Assessment of embryo morphology following perinatal exposure to aspirin, ibuprofen and paracetamol using whole embryo culture system.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Ibuprofen; | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation: A systematic review.
Topics: Female; Humans; Ibuprofen; Mifepristone; Misoprostol; Observational Studies as Topic; Pain; Pain Man | 2022 |
Management of pain associated with up-to-9-weeks medical termination of pregnancy (MToP) using mifepristone-misoprostol regimens: expert consensus based on a systematic literature review.
Topics: Abortifacient Agents, Steroidal; Abortion, Induced; Anti-Inflammatory Agents, Non-Steroidal; Consens | 2020 |
An Overview of Systematic Reviews of Randomized-Controlled Trials for Preventing Necrotizing Enterocolitis in Preterm Infants.
Topics: Administration, Oral; Adrenal Cortex Hormones; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing | 2020 |
Bartter syndrome: An infrequent tubulopathy of prenatal onset.
Topics: Adult; Bartter Syndrome; Female; Hearing Loss, Sensorineural; Humans; Ibuprofen; Infant; Infant, New | 2019 |
The comparison of ibuprofen versus acetaminophen for blood pressure in preeclampsia: a meta-analysis of randomized controlled studies.
Topics: Acetaminophen; Arterial Pressure; Blood Pressure; Female; Humans; Ibuprofen; Pre-Eclampsia; Pregnanc | 2022 |
Paracetamol versus ibuprofen for the treatment of patent ductus arteriosus in preterm neonates: a meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Infant, Newborn; Infant, Premat | 2018 |
Clinical pharmacology of ibuprofen and indomethacin in preterm infants with patent ductus arteriosus.
Topics: Cyclooxygenase Inhibitors; Dinoprostone; Drug Administration Schedule; Ductus Arteriosus, Patent; Fe | 2014 |
Safety of therapeutics used in management of patent ductus arteriosus in preterm infants.
Topics: Acetaminophen; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indo | 2015 |
Caffeine as an analgesic adjuvant for acute pain in adults.
Topics: Acetaminophen; Acute Pain; Adolescent; Adult; Aged; Analgesics; Caffeine; Chemotherapy, Adjuvant; Di | 2014 |
Analgesic use - prevalence, biomonitoring and endocrine and reproductive effects.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Commerce; | 2016 |
[Analgesic drugs during pregnancy].
Topics: Abnormalities, Drug-Induced; Acetaminophen; Acute Pain; Analgesics; Analgesics, Opioid; Anticonvulsa | 2016 |
Ibuprofen lysine for the prevention and treatment of patent ductus arteriosus.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Fetus; Humans; Ib | 2008 |
Managing the patent ductus arteriosus in the premature neonate: a new look at what we thought we knew.
Topics: Acetaminophen; Biomarkers; Dose-Response Relationship, Drug; Ductus Arteriosus, Patent; Echocardiogr | 2012 |
Caffeine as an analgesic adjuvant for acute pain in adults.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Caffeine; Chemotherapy, Adjuvant; Female; Headache; Hu | 2012 |
Role of prostaglandins, prostacyclin, and thromboxanes in the control of prenatal patency and postnatal closure of the ductus arteriosus.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Ductus Arteriosus; Ductus Arteriosus, P | 1980 |
NSAID-induced nephrotoxicity from the fetus to the child.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Ductus Arteriosus, Patent; Female; | 2001 |
[Current opinions on embryotoxic and teratogenic effects of ibuprofen].
Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents, Non-Steroidal; Female; Gastroschisis; Humans; | 2001 |
Antiinflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Benzylidene Compounds; Chi | 1977 |
41 trials available for ibuprofen and Pregnancy
| Article | Year |
|---|---|
The experience of pain in real-time during medication abortion.
Topics: Abortion, Induced; Acetaminophen; Analgesics; Analgesics, Opioid; Female; Humans; Ibuprofen; Mifepri | 2022 |
Intranasal fentanyl for first-trimester uterine aspiration pain: A randomized controlled trial.
Topics: Abortion, Induced; Double-Blind Method; Female; Fentanyl; Humans; Ibuprofen; Pelvic Pain; Pregnancy; | 2022 |
The dilemma of feeding during the treatment of patent ductus arteriosus with oral ibuprofen in preterm infants ≤30 weeks of gestation-a randomized controlled trial.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Infant, Newborn; In | 2023 |
Outpatient Treatment With Gabapentin in Women With Severe Acute Pain After Cesarean Delivery Is Ineffective: A Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Acetaminophen; Acute Pain; Analgesics, Opioid; Double-Blind Method; Female; Gabapentin; Humans; Ibup | 2023 |
A randomized-controlled trial to assess the effect of ibuprofen on postpartum blood pressure in women with hypertensive disorders of pregnancy.
Topics: Acetaminophen; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Blood Pre | 2019 |
Ibuprofen and Postpartum Blood Pressure in Women With Hypertensive Disorders of Pregnancy: A Randomized Controlled Trial.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Blood Pressure Determination; Double | 2019 |
Cannabinoids for Pain Control During Medical Abortion: A Randomized Controlled Trial.
Topics: Abortion, Induced; Adult; Analgesics, Non-Narcotic; Double-Blind Method; Dronabinol; Female; Humans; | 2020 |
Opioid prescription for pain after osmotic dilator placement in abortion care: A randomized controlled trial.
Topics: Analgesics, Opioid; Double-Blind Method; Female; Humans; Ibuprofen; Oxycodone; Pain; Pain, Postopera | 2021 |
Comparison of 3 protocols for analgesia control after cesarean delivery: a randomized controlled trial.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Adult; Analgesia; Analgesics; Anal | 2019 |
Educational Video on Pain Management and Subsequent Opioid Use After Cesarean Delivery: A Randomized Controlled Trial.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Cesarean Section; Female; Humans; Ibuprofen; Opioid-Relate | 2021 |
Effect of ibuprofen vs acetaminophen on postpartum hypertension in preeclampsia with severe features: a double-masked, randomized controlled trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 2018 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Prophylactic compared with therapeutic ibuprofen analgesia in first-trimester medical abortion: a randomized controlled trial.
Topics: Abortifacient Agents, Steroidal; Abortion, Induced; Adolescent; Adult; Analgesia; Analgesics, Non-Na | 2013 |
Continuous wound infiltration with ropivacaine for analgesia after caesarean section: a randomised, placebo-controlled trial.
Topics: Abdominal Injuries; Acetaminophen; Adult; Amides; Analgesia; Anesthesia, Obstetrical; Anesthesia, Sp | 2014 |
Nitrous oxide for pain management of first trimester surgical abortion -- a randomized controlled pilot study.
Topics: Abortion, Induced; Administration, Oral; Adult; Analgesics, Non-Narcotic; Anesthetics, Inhalation; D | 2015 |
Differences in risk for type 1 and type 2 ovarian cancer in a large cancer screening trial.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Contraceptives, Oral, Hormonal; Early Detection of Ca | 2016 |
Ibuprofen versus acetaminophen as a post-partum analgesic for women with severe pre-eclampsia: randomized clinical study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Blood Pressure; Female; Humans; Ibuprofen; Postpartu | 2017 |
Two prophylactic medication approaches in addition to a pain control regimen for early medical abortion < 63 days' gestation with mifepristone and misoprostol: study protocol for a randomized, controlled trial.
Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Adolescent; | 2016 |
Ibuprofen versus acetaminophen for the relief of perineal pain after childbirth: a randomized controlled trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Episiotomy; | 2008 |
Paracervical block with combined ketorolac and lidocaine in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2009 |
Paracervical block with combined ketorolac and lidocaine in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2009 |
Paracervical block with combined ketorolac and lidocaine in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2009 |
Paracervical block with combined ketorolac and lidocaine in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2009 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Pre-emptive effect of ibuprofen versus placebo on pain relief and success rates of medical abortion: a double-blind, randomized, controlled study.
Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Administrati | 2012 |
Marie Stopes Society, Pakistan: 1000 cases of quinacrine sterilization (QS).
Topics: Ambulatory Care Facilities; Cyclooxygenase Inhibitors; Drug Implants; Fallopian Tubes; Female; Follo | 2003 |
10-year follow-up of women who elected quinacrine sterilization (QS) in Wonosobo, Central Java, Indonesia.
Topics: Adult; Cyclooxygenase Inhibitors; Drug Implants; Female; Follow-Up Studies; Humans; Ibuprofen; Indon | 2003 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain catastrophizing, response to experimental heat stimuli, and post-cesarean section pain.
Topics: Adult; Analgesics, Non-Narcotic; Cesarean Section; Female; Hot Temperature; Humans; Ibuprofen; Pain; | 2007 |
Impact of ibuprofen administration on renal drug clearance in the first weeks of life.
Topics: Age Factors; Amikacin; Anti-Bacterial Agents; Aspirin; Betamethasone; Birth Weight; Cyclooxygenase I | 2006 |
Intravenous acetaminophen vs oral ibuprofen in combination with morphine PCIA after Cesarean delivery.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; A | 2006 |
A randomized trial of tramadol versus ibuprofen as an adjunct to pain control during vacuum aspiration abortion.
Topics: Abortion, Therapeutic; Adult; Analgesics; Female; Humans; Ibuprofen; Pain; Pregnancy; Tramadol; Trea | 2008 |
Ibuprofen versus placebo in the relief of post-episiotomy pain.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Episiotomy; Female; Humans; Ibuprofen; Pain, P | 1981 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprof | 1995 |
Methotrexate and misoprostol for abortion at 57-63 days gestation.
Topics: Abortion, Induced; Acetaminophen; Administration, Oral; Adult; Chorionic Gonadotropin; Codeine; Coli | 1994 |
Quinacrine pellet nonsurgical female sterilization in Wonosobo, Indonesia.
Topics: Adult; Cervix Uteri; Female; Humans; Ibuprofen; Indonesia; Pregnancy; Prospective Studies; Quinacrin | 1997 |
Analgesic efficacy of a hydrocodone with ibuprofen combination compared with ibuprofen alone for the treatment of acute postoperative pain.
Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroid | 1997 |
The effect of dextromethorphan, alone or in combination with ibuprofen, on postoperative pain after minor gynaecological surgery.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Dextromethorphan; Double-Blind Method; Drug Therapy, | 2000 |
Effect of a single dose of ibuprofen lysinate before embryo transfer on pregnancy rates in cows.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Embryo Implantation; Embryo Transfer; Fema | 2001 |
Nonsurgical female sterilization: comparison of intrauterine application of quinacrine alone or in combination with ibuprofen.
Topics: Adult; Female; Humans; Ibuprofen; Instillation, Drug; Pregnancy; Quinacrine; Reproducibility of Resu | 2001 |
Pain control in medical abortion.
Topics: Abortion, Induced; Acetaminophen; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Anti-Inflammator | 2001 |
Relief of dysmenorrhea with the prostaglandin synthetase inhibitor ibuprofen: effect on prostaglandin levels in menstrual fluid.
Topics: Adult; Body Fluids; Double-Blind Method; Dysmenorrhea; Female; Follow-Up Studies; Humans; Ibuprofen; | 1979 |
[Analgesic effect of ibuprofen in pain after episiotomy].
Topics: Acetaminophen; Adult; Double-Blind Method; Drug Evaluation; Episiotomy; Female; Humans; Ibuprofen; P | 1992 |
Analgesic efficacy of two ibuprofen-codeine combinations for the treatment of postepisiotomy and postoperative pain.
Topics: Adult; Cesarean Section; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; | 1987 |
125 other studies available for ibuprofen and Pregnancy
| Article | Year |
|---|---|
Adenomyosis.
Topics: Adenomyosis; Endometriosis; Female; Hormonal Contraception; Humans; Hysterectomy; Ibuprofen; Intraut | 2022 |
Use of Scheduled Nonopioid Analgesia to Decrease Inpatient Opioid Consumption After Scheduled Cesarean Birth.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans; Ibuprofen; I | 2022 |
2022 Taiwan Guidelines for Acute Treatment of Migraine.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Caffeine; Calcitonin G | 2022 |
Cocktails of NSAIDs and 17α Ethinylestradiol at Environmentally Relevant Doses in Drinking Water Alter Puberty Onset in Mice Intergenerationally.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drinking Water; Endocrine Disruptors; Ethinyl Estr | 2023 |
Early neurodevelopmental outcomes of extreme preterm infants exposed to paracetamol: a retrospective cohort study.
Topics: Acetaminophen; Birth Weight; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Infant; Infant, N | 2023 |
Increasing the dose of ibuprofen with postnatal age to close a hemodynamically significant patent ductus arteriosus in very preterm infants.
Topics: Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Infant, Newborn; Infant, Premature; Infant, Pr | 2023 |
In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice.
Topics: Acetaminophen; Aging; Animals; Animals, Newborn; Cell Proliferation; Female; Fertility; Forkhead Box | 2019 |
Associations of prenatal or infant exposure to acetaminophen or ibuprofen with mid-childhood executive function and behaviour.
Topics: Acetaminophen; Age Factors; Analgesics, Non-Narcotic; Child; Child Behavior; Child Behavior Disorder | 2020 |
Maternal exposure to ibuprofen can affect the programming of the hypothalamus of the male offspring.
Topics: Animals; Brain; Female; Hypothalamus; Ibuprofen; Male; Maternal Exposure; Pregnancy; Prenatal Exposu | 2020 |
The effect of a scheduled regimen of acetaminophen and ibuprofen on opioid use following cesarean delivery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2020 |
Ventilatory and carotid body responses to acute hypoxia in rats exposed to chronic hypoxia during the first and second postnatal weeks.
Topics: Age Factors; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Carotid Body; Femal | 2020 |
Pain during medical abortion in early pregnancy in teenage and adult women.
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Acetaminophen; Adolescent; Adult; Analgesics; | 2020 |
Association Between Male Use of Pain Medication and Fecundability.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Birth Rate; Cohort Studies; | 2020 |
A Project to Reduce Opioid Administration for Women in the Postpartum Period.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans; Ibuprofen; Ohio; Pain M | 2020 |
Effect of In Utero Non-Steroidal Anti-Inflammatory Drug Therapy for Severe Ebstein Anomaly or Tricuspid Valve Dysplasia (NSAID Therapy for Fetal Ebstein anomaly).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Constriction; Ductus Arteriosus; Duration of Therapy; Ebste | 2021 |
Predictive factors for surgical treatment in preterm neonates with necrotizing enterocolitis: a multicenter case-control study.
Topics: Case-Control Studies; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Female; Humans; Ibuprof | 2021 |
Association of hemoglobin and spontaneous closure of the ductus arteriosus during the transitional period in very low birth weight infants.
Topics: Case-Control Studies; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Hemoglobins; Humans; Ibu | 2021 |
First trimester naproxen exposure and outcome of pregnancy - A German case series.
Topics: Abortion, Spontaneous; Anencephaly; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Female; | 2021 |
Agreement Between Maternal Report and Medical Records During Pregnancy: Medications for Rheumatoid Arthritis and Asthma.
Topics: Adult; Albuterol; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Asthma; Et | 2018 |
Neonatal gastric perforations in very low birth weight infants: a single center experience and review of the literature.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Asphyxia Neonatorum; Chorioamnionitis; Ductus Arteriosus, P | 2018 |
Use of paracetamol, ibuprofen or aspirin in pregnancy and risk of cerebral palsy in the child.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Aspirin; Cerebral Palsy; Cohort Studies; Female; Hum | 2018 |
Ibuprofen is deleterious for the development of first trimester human fetal ovary ex vivo.
Topics: Apoptosis; Cell Proliferation; Cyclooxygenase Inhibitors; Embryonic Development; Female; Humans; Ibu | 2018 |
Activated NO pathway in uterine arteries during pregnancy in an IUGR rat model.
Topics: Animals; Cyclooxygenase Inhibitors; Female; Fetal Growth Retardation; Ibuprofen; NG-Nitroarginine Me | 2018 |
No evidence of adverse pregnancy outcome after exposure to ibuprofen in the first trimester - Evaluation of the national Embryotox cohort.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Analgesics; Anti-Inflammatory Agents, Non-Steroi | 2018 |
Pain relief: determining the safety of ibuprofen with postpartum preeclampsia.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Hypertension; Ibuprofe | 2018 |
Continuous local bupivacaine wound infusion with neuraxial morphine reduces opioid consumption after cesarean delivery.
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, S | 2019 |
Intergenerational effects on mouse sperm quality after in utero exposure to acetaminophen and ibuprofen.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Embryo, M | 2019 |
Does Postmenstrual Age Affect Medical Patent Ductus Arteriosus Treatment Success in Preterm Infants?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; | 2019 |
Female-biased embryonic death from inflammation induced by genomic instability.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Proliferation; DNA Damage; DNA Helicases; DNA | 2019 |
Non-steroidal anti-inflammatory drug prescriptions from the 6
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Databases, Factual; Drug Prescriptions; Female; Huma | 2019 |
Larger Dose Reductions of Vancomycin Required in Neonates with Patent Ductus Arteriosus Receiving Indomethacin versus Ibuprofen.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen | 2019 |
Effects of ibuprofen, diclofenac, naproxen, and piroxicam on the course of pregnancy and pregnancy outcome: a prospective cohort study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Diclofenac; Female; Humans; Ibuprofe | 2013 |
Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Ibuprofen; Naproxen; Piroxicam; | 2014 |
Risk factors of mild rectal bleeding in very low birth weight infants: a case control study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Feces; Female; Gastrointestina | 2013 |
Outcomes of primary ligation of patent ductus arteriosus compared with secondary ligation after pharmacologic failure in very-low-birth-weight infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiac Surgical Procedures; Ductus Arteriosus, Patent; Fem | 2014 |
Effect of NSAIDs and diuretics on nephrogenesis in an ex vivo embryogenic kidney model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Morphogenetic Protein 7; Diuretics; Female; F | 2013 |
[Aspirin for migraine in pregnancy. This recommendation seems questionable].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Contraindications; Female; Humans; Ibuprofen; Infa | 2013 |
Marked variability in peri-partum anesthetic management of patients on buprenorphine maintenance therapy (BMT): can there be an underlying acute opioid induced hyperalgesia precipitated by neuraxial opioids in BMT patients?
Topics: Acetaminophen; Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Buprenorphine; Cesarea | 2013 |
Indomethacin administered early in the postnatal period results in reduced glomerular number in the adult rat.
Topics: Animals; Animals, Newborn; Body Weight; Cyclooxygenase Inhibitors; Female; Ibuprofen; Indomethacin; | 2014 |
Prenatal and infant exposure to acetaminophen and ibuprofen and the risk for wheeze and asthma in children.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Chi | 2015 |
Acetaminophen and childhood asthma: pill-popping at our peril?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Female; Hu | 2015 |
NSAIDs and spontaneous abortions - true effect or an indication bias?
Topics: Abortion, Spontaneous; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Femal | 2015 |
Assessment of maternal drug intake by urinary bio monitoring during pregnancy and postpartally until the third perinatal year.
Topics: Acetaminophen; Contraindications; Female; Humans; Ibuprofen; Imidazoles; Nonprescription Drugs; Post | 2016 |
Utilization of over the counter medication among pregnant women; a cross-sectional study conducted at Isra University Hospital, Hyderabad.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 2016 |
Acute interstitial nephritis due to flecainide therapy in the 38(th) week of pregnancy.
Topics: Acute Disease; Acute Kidney Injury; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; | 2016 |
Short-term exposure and long-term consequences of neonatal exposure to Δ(9)-tetrahydrocannabinol (THC) and ibuprofen in mice.
Topics: Analgesics, Non-Narcotic; Animals; Animals, Newborn; Developmental Disabilities; Dose-Response Relat | 2016 |
Editorial: Patent Ductus Arteriosus in Extremely Premature Neonates.
Topics: Anterior Cerebral Artery; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Echocardiography, Do | 2016 |
Preconception use of pain-relievers and time-to-pregnancy: a prospective cohort study.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Aspirin; Female; Humans; Ibuprofen; Internet; | 2017 |
Association of Prenatal Ibuprofen Exposure with Birth Weight and Gestational Age: A Population-Based Sibling Study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; Child; Female; Gestational Age; Humans | 2016 |
Ibuprofen results in alterations of human fetal testis development.
Topics: Female; Fetus; Gene Expression Regulation, Developmental; Humans; Ibuprofen; Male; Organogenesis; Pr | 2017 |
Factors affecting postnatal changes in serum creatinine in preterm infants with gestational age <32 weeks.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Creatinine; Ductus Arteriosus, Patent; Female; Gestational | 2009 |
Delayed neonatal closure of the ductus arteriosus following early in utero exposure to indomethacin in the rat.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibito | 2009 |
Indomethacin, ibuprofen and gentamicin administered during late stages of glomerulogenesis do not reduce glomerular number at 14 days of age in the neonatal rat.
Topics: Analgesics, Non-Narcotic; Animals; Animals, Newborn; Anti-Bacterial Agents; Body Weight; Cardiovascu | 2009 |
Is there an optimal timing for surgical ligation of patent ductus arteriosus in preterm infants?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apgar Score; Birth Weight; Ductus Arteriosus, Patent; Femal | 2009 |
Management of acute postpartum pain in patients maintained on methadone or buprenorphine during pregnancy.
Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Buprenorphine; Controlled Clinic | 2009 |
Effects of prenatal immune activation on hippocampal neurogenesis in the rat.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroida | 2009 |
Maternal use of acetaminophen, ibuprofen, and acetylsalicylic acid during pregnancy and risk of cryptorchidism.
Topics: Acetaminophen; Adult; Aspirin; Cryptorchidism; Cyclooxygenase Inhibitors; Denmark; Female; Humans; I | 2010 |
Are cytochrome P450 CYP2C8 and CYP2C9 polymorphisms associated with ibuprofen response in very preterm infants?
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Ductus Arteriosus, | 2010 |
Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Cohort Studies; Cryptorchidism; Female; Humans; Ibuprof | 2011 |
Patent ductus arteriosus ligation alters pulmonary gene expression in preterm baboons.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Femal | 2011 |
Perinatal drug exposure and renal function in very preterm infants.
Topics: Analgesics, Non-Narcotic; Female; Gestational Age; Glomerular Filtration Rate; Humans; Ibuprofen; In | 2011 |
Luteinized unruptured follicle syndrome increased by inactive disease and selective cyclooxygenase 2 inhibitors in women with inflammatory arthropathies.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Chi-Square Distribution; Cyclo | 2011 |
Analgesics during pregnancy and cryptorchidism: additional analyses.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Cryptorchidism; Cyclooxygenase Inhibitors; Female; | 2011 |
Fetal intracranial hemorrhage at 24 weeks' gestation.
Topics: Adolescent; Fatal Outcome; Female; Gestational Age; Humans; Ibuprofen; Intracranial Hemorrhages; Lab | 2011 |
Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2.
Topics: Analysis of Variance; Animals; Blotting, Western; Breast Neoplasms; Carcinoma, Ductal; Celecoxib; Ce | 2011 |
Transversus abdominis plane catheters for post-cesarean delivery analgesia: a series of five cases.
Topics: Abdominal Muscles; Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; | 2012 |
Effects of ibuprofen treatment on the developing preterm baboon kidney.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Body Weight; Dri | 2012 |
Does treatment of patent ductus arteriosus with cyclooxygenase inhibitors affect neonatal regional tissue oxygenation?
Topics: Analysis of Variance; Blood Gas Analysis; Cerebrovascular Circulation; Chi-Square Distribution; Chro | 2012 |
Pediatric emergency medicine: legal briefs.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aortic Aneurysm; Aortic Dissection; Appendicitis; | 2012 |
Non-prescription medicines for pain and fever--a comparison of recommendations and counseling from staff in pharmacy and general sales stores.
Topics: Acetaminophen; Analgesics; Antipyretics; Aspirin; Child; Commerce; Contraindications; Counseling; Fe | 2013 |
The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK.
Topics: Adenocarcinoma; Animals; Arachidonic Acid; Cricetinae; Cyclooxygenase Inhibitors; DNA Primers; Ethan | 2002 |
Over-the-counter oral analgesia for postcesarean pain.
Topics: Administration, Oral; Analgesia, Patient-Controlled; Analgesics; Capsules; Cesarean Section; Drug Ad | 2002 |
Prescription, over-the-counter, and herbal medicine use in a rural, obstetric population.
Topics: Adult; Drug Prescriptions; Female; Herbal Medicine; Humans; Ibuprofen; Minerals; Nonprescription Dru | 2003 |
The effect of the cyclooxygenase blockers, ibuprofen on the development of glomeruli in Sprague-Dawley rats.
Topics: Animals; Cyclooxygenase Inhibitors; Female; Ibuprofen; Kidney Glomerulus; Pregnancy; Pregnancy, Anim | 2003 |
Proteinase-activated receptor-2 activation induces uterine contractility in term pregnant rats that is not dependent on mast cell activation and cyclo-oxygenase products.
Topics: Animals; Chlorpheniramine; Cimetidine; Cromolyn Sodium; Dose-Response Relationship, Drug; Female; Hi | 2003 |
Effect of selective vs. non-selective cyclo-oxygenase inhibitors on fetal membrane prostaglandin synthesis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cycloox | 2003 |
[Mondor's disease].
Topics: Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; F | 2003 |
PFA-100 and regional analgesia in a parturient after ibuprofen overdose.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Contraindications; Dru | 2004 |
Developmental toxicity evaluation of ibuprofen and tolmetin administered in triple daily doses to Wistar CRL:(WI)WUBR rats.
Topics: Animals; Aspirin; Body Weight; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; | 2004 |
Degranulation of uterine mast cell modifies contractility of isolated myometrium from pregnant women.
Topics: Cell Degranulation; Chlorpheniramine; Cimetidine; Cromolyn Sodium; Female; Histamine H1 Antagonists; | 2004 |
Comparison of developmental toxicity of selective and non-selective cyclooxygenase-2 inhibitors in CRL:(WI)WUBR Wistar rats--DFU and piroxicam study.
Topics: Abdominal Wall; Abnormalities, Drug-Induced; Alanine Transaminase; Animals; Aspartate Aminotransfera | 2005 |
[Aspirin, paracetamol, ibuprofen: analgesics in the family medicine cabinet].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Contraind | 2005 |
Use of over-the-counter medications during pregnancy.
Topics: Acetaminophen; Ephedrine; Female; Humans; Ibuprofen; Nonprescription Drugs; Pregnancy | 2005 |
Skeletal developmental effects of selective and nonselective cyclooxygenase-2 inhibitors administered through organogenesis and fetogenesis in Wistar CRL:(WI)WUBR rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Development; Cathepsin K; Cathepsins; Chondro | 2005 |
Combined treatment potentiates the developmental toxicity of ibuprofen and acetazolamide in rats.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Animals, Newborn; Birth Weight; Body Weight; Ca | 2005 |
PAR-2 activating peptide-induced stimulation of pregnant rat myometrium contractile activity partly involves the other membrane receptors.
Topics: Animals; Atropine; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Female; Hydraz | 2007 |
Comparative effects of early postnatal ibuprofen and indomethacin on VEGF, IGF-I, and GH during rat ocular development.
Topics: Animals; Animals, Newborn; Cyclooxygenase Inhibitors; Eye; Female; Growth Hormone; Ibuprofen; Indome | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Renal glomeruli and tubular injury following indomethacin, ibuprofen, and gentamicin exposure in a neonatal rat model.
Topics: Analgesics, Non-Narcotic; Animals; Animals, Newborn; Anti-Bacterial Agents; Cardiovascular Agents; F | 2007 |
Recurrent Kikuchi-Fujimoto necrotizing lymphadenitis during pregnancy.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Histiocytic Necrotizing Lymphadenitis; Human | 2008 |
Patterns of pregnancy exposure to prescription FDA C, D and X drugs in a Canadian population.
Topics: Adult; Albuterol; Contraceptives, Oral; Cross-Sectional Studies; Drug Prescriptions; Drug-Related Si | 2008 |
Ibuprofen overdose and exposure in utero: results from a postmarketing voluntary reporting system.
Topics: Adolescent; Adult; Child; Child, Preschool; Drug Information Services; Female; Fetus; Humans; Ibupro | 1984 |
Effect of ibuprofen and naproxen on implantation and pregnancy in rat.
Topics: Animals; Embryo Implantation; Female; Ibuprofen; Male; Naproxen; Pregnancy; Pregnancy, Animal; Rats | 1984 |
Ibuprofen without a prescription.
Topics: Central Nervous System Diseases; Drug Interactions; Female; Hematologic Diseases; Humans; Ibuprofen; | 1984 |
Effect of intrauterine administration of antiprostaglandin drugs on implantation in the rat.
Topics: Animals; Aspirin; Embryo Implantation; Female; Ibuprofen; Indomethacin; Injections; Pregnancy; Prost | 1981 |
The role of arachidonic acid and/or its metabolites in embryo implantation initiated by epidermal growth factor (EGF).
Topics: Animals; Arachidonic Acid; Dexamethasone; Dinoprostone; Embryo Implantation; Epidermal Growth Factor | 1995 |
Evaluation of the rat embryo culture system as a predictive test for human teratogens.
Topics: Abnormalities, Drug-Induced; Animals; Captopril; Diphenhydramine; DNA; Embryo, Mammalian; False Nega | 1994 |
"Stuck twin" syndrome associated with congenital cytomegalovirus infection.
Topics: Amniocentesis; Cytomegalovirus Infections; Ductus Arteriosus; Female; Fetofetal Transfusion; Fetus; | 1993 |
Comparison of the efficacy of intrauterine diclofenac and ibuprofen pellets as adjuvants to quinacrine nonsurgical female sterilization.
Topics: Diclofenac; Female; Humans; Ibuprofen; India; Pregnancy; Quinacrine; Sterilization, Reproductive; Ut | 1995 |
Increased ductal responsiveness to PGE2 after maternal treatment with aspirin and ibuprofen.
Topics: Administration, Oral; Animals; Animals, Newborn; Aspirin; Cesarean Section; Dinoprostone; Ductus Art | 1998 |
Four-year clinical evaluation of quinacrine pellets for non-surgical female sterilization.
Topics: Administration, Intravaginal; Adult; Contraception; Fallopian Tubes; Female; Follow-Up Studies; Huma | 1998 |
[Effects of amniotic fluid embolism-like plasma on isolated perfused rabbit lungs].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Embolism, Amniotic Fluid; Female; | 1997 |
Influence of oestrous cycle and pregnancy on the reactivity of the rat mesenteric vascular bed.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Est | 2000 |
The renal hemodynamic effects of ibuprofen in the newborn rabbit.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Femal | 2000 |
Oestrous cycle and pregnancy alter the reactivity of the rat uterine vasculature.
Topics: Acetylcholine; Adrenergic Agonists; Animals; Biological Factors; Cyclooxygenase Inhibitors; Diestrus | 2000 |
Analysis of nonsteroidal antiinflammatory drugs in meconium and its relation to persistent pulmonary hypertension of the newborn.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bronchodilator Agents; Extracorporeal Membrane Oxy | 2001 |
Cutaneous drug reaction case reports: from the world literature.
Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Aged; Amlodipine; Anti-Bacterial Agents; Anti-I | 2001 |
Maternal medication use and risks of gastroschisis and small intestinal atresia.
Topics: Acetaminophen; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Aspirin; Canada; Ephedrine; Fema | 2002 |
Migraine in women.
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Contraindications; Female; Hum | 2002 |
[Use of antibiotics and side effects of an anti-inflammatory agent, ibuprofen, in the aged].
Topics: Aged; Bacitracin; Colistin; Female; Humans; Ibuprofen; Phenylpropionates; Pregnancy; Pseudomonas Inf | 1977 |
Age-dependent changes in the response of the lamb ductus arteriosus to oxygen and ibuprofen.
Topics: Animals; Dose-Response Relationship, Drug; Ductus Arteriosus; Female; Gestational Age; Ibuprofen; Ox | 1979 |
Inhibition of prostaglandin synthesis and contractility in the rabbit and rat uterus by ibuprofen.
Topics: Animals; Depression, Chemical; Female; Ibuprofen; Labor, Obstetric; Phenylpropionates; Postpartum Pe | 1977 |
The treatment of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Child; Chloroquine; Female; Gold; Humans; Hydroxychl | 1977 |
The antagonism by anti-inflammatory analgesics of prostaglandin f 2 alpha-induced contractions of human and rabbit myometrium in vitro.
Topics: Abortion, Induced; Animals; Anti-Inflammatory Agents; Aspirin; Drug Antagonism; Female; Ibuprofen; I | 1975 |
Effect of ibuprofen on alcohol-induced teratogenesis in mice.
Topics: Abnormalities, Drug-Induced; Analysis of Variance; Animals; Aspirin; Body Weight; Ethanol; Female; F | 1991 |
A prostacyclin analogue crosses the in vitro perfused human placenta and improves transfer in some pathologic states.
Topics: Antipyrine; Diabetes Mellitus, Type 1; Epoprostenol; Female; Humans; Hypertension; Ibuprofen; In Vit | 1991 |
Transplacental cardiovascular effects of four popular analgesics in rats.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Cardiomegaly; Constriction, Pathologic; Ductus Arterios | 1990 |
Oligohydramnios in each sac of a triplet gestation caused by Motrin--fulfilling Kock's postulates.
Topics: Adult; Amniotic Fluid; Female; Humans; Ibuprofen; Indomethacin; Obstetric Labor, Premature; Pregnanc | 1990 |
Oligohydramnios associated with prostaglandin synthetase inhibitors in preterm labour.
Topics: Adult; Amniotic Fluid; Birth Weight; Female; Gestational Age; Humans; Ibuprofen; Indomethacin; Infan | 1990 |
[Metoxibutropate].
Topics: Adult; Aged; Animals; Dysmenorrhea; Female; Guaiacol; Humans; Ibuprofen; Mice; Pain; Papio; Pregnanc | 1989 |
Complications of uterine leiomyomas in pregnancy.
Topics: Adult; Cesarean Section; Female; Fetal Membranes, Premature Rupture; Humans; Ibuprofen; Labor Presen | 1989 |
Cyclooxygenase inhibition reduces placental transfer: reversal by carbacyclin.
Topics: Antipyrine; Cyclooxygenase Inhibitors; Epoprostenol; Female; Humans; Ibuprofen; Indomethacin; Matern | 1987 |
Prescribing analgesics.
Topics: Acetaminophen; Aged; Analgesics; Anticoagulants; Aspirin; Child; Codeine; Diflunisal; Drug Hypersens | 1985 |
Stimulation of ovine placental lactogen secretion by arachidonic acid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Female; Fetal Blood; Gestational Age; Ibuprofen; Indom | 1985 |
Nonsteroidal anti-inflammatory agents. A review of the literature.
Topics: Absorption; Anti-Inflammatory Agents; Aspirin; Diflunisal; Drug Interactions; Female; Fenoprofen; Ha | 1985 |