Page last updated: 2024-10-28

ibuprofen and Periodontitis

ibuprofen has been researched along with Periodontitis in 12 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)

Research Excerpts

ExcerptRelevanceReference
"To compare the incidence of postoperative pain of chronic periapical periodontitis patients with root canal therapy between Han and Uygur, and the effect of ibuprofen in reducing endodontic flare-up after single-visit root canal therapy between Uyghur and Han patients with chronic apical periodontitis, in order to provide a basis for clinical administration."9.24[Comparison of the differences in pain and the effect of ibuprofen in reducing endodontic flare-up after single-visit root canal therapy between Uyghur and Han patients with chronic apical periodontitis]. ( Wan, N; Wang, XY; Wu, PL; Yan, L, 2017)
"Paw edema was analyzed using a plethysmometer."5.48Systemic treatment with resveratrol reduces the progression of experimental periodontitis and arthritis in rats. ( Casarin, RCV; Casati, MZ; Cirano, FR; Corrêa, MG; Napimoga, MH; Pimentel, SP; Pires, PR; Ribeiro, FV, 2018)
"To compare the incidence of postoperative pain of chronic periapical periodontitis patients with root canal therapy between Han and Uygur, and the effect of ibuprofen in reducing endodontic flare-up after single-visit root canal therapy between Uyghur and Han patients with chronic apical periodontitis, in order to provide a basis for clinical administration."5.24[Comparison of the differences in pain and the effect of ibuprofen in reducing endodontic flare-up after single-visit root canal therapy between Uyghur and Han patients with chronic apical periodontitis]. ( Wan, N; Wang, XY; Wu, PL; Yan, L, 2017)
"The aim of this controlled clinical trial was to investigate the analgesic efficacy and tolerability of ibuprofen arginine in patients with mild-to-moderate periodontitis during and after non-surgical periodontal treatment."5.12Ibuprofen arginine for pain control during scaling and root planing: a randomized, triple-blind trial. ( Bernasconi, C; Bless, K; Ettlin, A; Ettlin, DA; Gallo, LM; Palla, S; Puhan, M; Tillmann, HC, 2006)
"This clinical trial investigated the influence of short-term ibuprofen therapy on the early phase of the treatment of adult chronic periodontitis."5.07The effect of systemic ibuprofen on gingival inflammation in humans. ( Taiyeb Ali, TB; Waite, IM, 1993)
"One approach of treating periodontitis is loading the NSAIDs in local drug delivery systems."1.48Development of hydrogels, oleogels, and bigels as local drug delivery systems for periodontitis. ( AbuRezeq, A; Hamed, R; Tarawneh, O, 2018)
"Paw edema was analyzed using a plethysmometer."1.48Systemic treatment with resveratrol reduces the progression of experimental periodontitis and arthritis in rats. ( Casarin, RCV; Casati, MZ; Cirano, FR; Corrêa, MG; Napimoga, MH; Pimentel, SP; Pires, PR; Ribeiro, FV, 2018)
"After 4 wk of treatment, periodontitis was initiated in one quadrant by the placement of silk ligatures."1.28Effects of topical applications of meclofenamic acid and ibuprofen on bone loss, subgingival microbiota and gingival PMN response in the primate Macaca fascicularis. ( Blodgett, RF; Brunsvold, M; Holt, SC; Kornman, KS, 1990)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (50.00)18.2507
2000's1 (8.33)29.6817
2010's5 (41.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yan, L1
Wang, XY1
Wan, N1
Wu, PL1
Hamed, R1
AbuRezeq, A1
Tarawneh, O1
Madhumathi, K1
Rubaiya, Y1
Doble, M1
Venkateswari, R1
Sampath Kumar, TS1
Corrêa, MG1
Pires, PR1
Ribeiro, FV1
Pimentel, SP1
Cirano, FR1
Napimoga, MH1
Casati, MZ1
Casarin, RCV1
Batool, F1
Agossa, K1
Lizambard, M1
Petit, C1
Bugueno, IM1
Delcourt-Debruyne, E1
Benkirane-Jessel, N1
Tenenbaum, H1
Siepmann, J1
Siepmann, F1
Huck, O1
Ettlin, DA1
Ettlin, A1
Bless, K1
Puhan, M1
Bernasconi, C1
Tillmann, HC1
Palla, S1
Gallo, LM1
Taiyeb Ali, TB1
Waite, IM1
O'Brien, TP1
Roszkowski, MT1
Wolff, LF1
Hinrichs, JE1
Hargreaves, KM1
el-Sherbiny, M1
Shoeib, MA1
Daahab, OA1
Ng, VW1
Bissada, NF1
Offenbacher, S1
Odle, BM1
Green, MD1
Mayambala, CS1
Smith, MA1
Fritz, ME1
van Dyke, TE1
Yeh, KC1
Sena, FJ1
Kornman, KS1
Blodgett, RF1
Brunsvold, M1
Holt, SC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Demonstration of OTC Naproxen Sodium's (Aleve's) Anti-inflammatory Action in Dental Implant Surgery Patients[NCT04694300]Phase 432 participants (Actual)Interventional2021-02-07Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for ibuprofen and Periodontitis

ArticleYear
[Comparison of the differences in pain and the effect of ibuprofen in reducing endodontic flare-up after single-visit root canal therapy between Uyghur and Han patients with chronic apical periodontitis].
    Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2017, Volume: 26, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Pain, Postoperative; Periapical Periodon

2017
Ibuprofen arginine for pain control during scaling and root planing: a randomized, triple-blind trial.
    Journal of clinical periodontology, 2006, Volume: 33, Issue:5

    Topics: Adult; Aged; Analgesics, Non-Narcotic; Arginine; Chronic Disease; Dental Scaling; Double-Blind Metho

2006
The effect of systemic ibuprofen on gingival inflammation in humans.
    Journal of clinical periodontology, 1993, Volume: 20, Issue:10

    Topics: Adult; Chronic Disease; Dental Prophylaxis; Female; Gingivitis; Humans; Ibuprofen; Male; Periodontit

1993
Effect of a non-steroidal anti-inflammatory drug on tissue levels of immunoreactive prostaglandin E2, immunoreactive leukotriene, and pain after periodontal surgery.
    Journal of periodontology, 1996, Volume: 67, Issue:12

    Topics: Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Dinoprostone; D

1996
Clinical evaluation of systemic doxycycline and ibuprofen administration as an adjunctive treatment for adult periodontitis.
    Journal of periodontology, 1998, Volume: 69, Issue:7

    Topics: Adult; Aged; Analysis of Variance; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; C

1998

Other Studies

7 other studies available for ibuprofen and Periodontitis

ArticleYear
Development of hydrogels, oleogels, and bigels as local drug delivery systems for periodontitis.
    Drug development and industrial pharmacy, 2018, Volume: 44, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding;

2018
Antibacterial, anti-inflammatory, and bone-regenerative dual-drug-loaded calcium phosphate nanocarriers-in vitro and in vivo studies.
    Drug delivery and translational research, 2018, Volume: 8, Issue:5

    Topics: 3T3 Cells; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Biocompatible Materials; Bone R

2018
Systemic treatment with resveratrol reduces the progression of experimental periodontitis and arthritis in rats.
    PloS one, 2018, Volume: 13, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cartilage, Articular; Dis

2018
In-situ forming implants loaded with chlorhexidine and ibuprofen for periodontal treatment: Proof of concept study in vivo.
    International journal of pharmaceutics, 2019, Oct-05, Volume: 569

    Topics: Animals; Anti-Infective Agents, Local; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Chlorhexi

2019
The effect of NSAID on T-cell ratios in marginal periodontitis.
    Egyptian dental journal, 1995, Volume: 41, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Biopsy; CD4-CD8 Ratio; Gingiva; Humans; Ibuprofen; Periodon

1995
Inhibition of human periodontal prostaglandin E2 synthesis with selected agents.
    Agents and actions, 1990, Volume: 29, Issue:3-4

    Topics: Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors

1990
Effects of topical applications of meclofenamic acid and ibuprofen on bone loss, subgingival microbiota and gingival PMN response in the primate Macaca fascicularis.
    Journal of periodontal research, 1990, Volume: 25, Issue:5

    Topics: Administration, Topical; Alveolar Bone Loss; Analysis of Variance; Animals; Anti-Inflammatory Agents

1990