ibuprofen has been researched along with Pain, Postoperative in 560 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Pain, Postoperative: Pain during the period after surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the analgesic efficacy and safety of different does of intravenous ibuprofen (IVIB) in the treatment of postoperative acute pain." | 9.69 | Analgesic Efficacy of Intravenous Ibuprofen in the Treatment of Postoperative Acute Pain: A Phase III Multicenter Randomized Placebo-ControlledDouble-Blind Clinical Trial. ( Li, TT; Liu, F; Pi, Y; Wang, TH; Xiong, LL; Zhou, HS, 2023) |
| "This study aims to evaluate the efficacy and safety of multiple or single-dosage intravenous ibuprofen (IVIB) in managing postoperative pain and fever in adults who are unable to take oral medications." | 9.41 | Intravenous ibuprofen in postoperative pain and fever management in adults: A systematic review and meta-analysis of randomized controlled trials. ( Chen, L; He, L; Tian, S; Wang, E; Zhai, S; Zhou, P, 2023) |
| "This study aimed to conduct a randomized prospective study about the efficacy of etodolac and ibuprofen on trismus, pain and edema regarding gender of patients submitted to impacted lower third molar teeth extraction." | 9.41 | The efficacy of etodolac and ibuprofen, regarding gender, on pain, edema and trismus after impacted lower third molar surgery: A randomized prospective clinical split-mouth study. ( Farnezi Bassi, AP; Faverani, LP; Reis, EN; Silva, LD, 2021) |
| "We did not find any statistically significant difference among CYP2C9 phenotypes related to ibuprofen response, although CYP2C9 poor metabolizers had a longer effect (higher pain relief at 6 hours)." | 9.41 | Influence of Genetic Polymorphisms on the Response to Tramadol, Ibuprofen, and the Combination in Patients With Moderate to Severe Pain After Dental Surgery. ( Abad-Santos, F; Acero, J; Borobia, AM; Burgueño, M; Cabaleiro, T; Carcas, AJ; Gálvez-Múgica, MÁ; Llanos, L; Martínez-Pérez, D; Muñoz-Guerra, MF; Ochoa, D; Puerro, M; Saiz-Rodríguez, M; Valdez-Acosta, S, 2021) |
| "Postprocedural pain scores and the number of patients who had increased abdominal pain after the procedure were significantly lower in the IV ibuprofen group." | 9.34 | IV Ibuprofen for Prevention of Post-ERCP Pancreatitis in Children: A Randomized Placebo-controlled Feasibility Study. ( Barth, BA; Gurram, B; Huang, R; Troendle, DM, 2020) |
| " Eligible patients (male and female subjects, aged 18-65 years, reporting pain intensity levels ≥40 mm on a 100-mm visual analog scale (VAS) after distal, first metatarsal bunionectomy) were randomized (3:3:3:2) to receive the FDC (ibuprofen 300 mg + acetaminophen 1000 mg), ibuprofen 300 mg, acetaminophen 1000 mg, or placebo (vehicle), administered as 15-minute intravenous infusions every 6 hours for 48 hours." | 9.30 | Efficacy and Safety of an Intravenous Acetaminophen/Ibuprofen Fixed-dose Combination After Bunionectomy: a Randomized, Double-blind, Factorial, Placebo-controlled Trial. ( Atkinson, HC; Daniels, SE; Gottlieb, IJ; Playne, R; Stanescu, I; Zhang, J, 2019) |
| "To compare the incidence of postoperative pain of chronic periapical periodontitis patients with root canal therapy between Han and Uygur, and the effect of ibuprofen in reducing endodontic flare-up after single-visit root canal therapy between Uyghur and Han patients with chronic apical periodontitis, in order to provide a basis for clinical administration." | 9.24 | [Comparison of the differences in pain and the effect of ibuprofen in reducing endodontic flare-up after single-visit root canal therapy between Uyghur and Han patients with chronic apical periodontitis]. ( Wan, N; Wang, XY; Wu, PL; Yan, L, 2017) |
| "To compare the efficacy of ibuprofen (IBU) and etodolac (ETO) for controlling pain, edema, and trismus after extraction of lower third molars." | 9.22 | Comparative Assessment of the Effect of Ibuprofen and Etodolac on Edema, Trismus, and Pain in Lower Third Molar Surgery: A Randomized Clinical Trial. ( Bassi, AP; Grossi de Oliveira, GA; Silva de Oliveira, JC, 2016) |
| " The aim of this study was to compare the effect on pain relief of on-demand versus regular prescription of ibuprofen after single-visit root canal treatment in teeth with irreversible pulpitis." | 9.19 | Comparison between prescription of regular or on-demand ibuprofen on postoperative pain after single-visit root canal treatment of teeth with irreversible pulpitis. ( Abbott, PV; Manochehrifar, H; Nakhaee, N; Parirokh, M; Sadr, S, 2014) |
| "Patients who received bupivacaine as the anesthetic agent for single-visit endodontic treatment of irreversible pulpitis in mandibular molars had significantly less early postoperative pain and used fewer analgesics than those who had lidocaine as the anesthetic." | 9.16 | Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis. ( Abbott, PV; Manochehrifar, H; Nakhaee, N; Parirokh, M; Reza Forghani, F; Yosefi, MH, 2012) |
| " The authors compare the effectiveness of a single intravenous dose of ketorolac with a single oral dose of either acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus." | 9.07 | Ketorolac versus acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus. ( Morrison, NA; Repka, MX, 1994) |
| "To compare carbon dioxide and nitrous oxide pneumoperitoneum with respect to intraoperative and postoperative pain during laparoscopic sterilization under local anesthesia." | 9.07 | The effect of nitrous oxide and carbon dioxide pneumoperitoneum on operative and postoperative pain during laparoscopic sterilization under local anesthesia. ( Ling, FW; Lipscomb, GH; McCord, ML; Summitt, RL, 1994) |
| " The earlier review included 20 studies (7238 participants) in valid comparisons, but because we used different outcomes for some headache studies, the number of participants in the analyses of the effects of caffeine is now 4262 when previously it was 5243." | 8.90 | Caffeine as an analgesic adjuvant for acute pain in adults. ( Derry, CJ; Derry, S; Moore, RA, 2014) |
| " Most studies used paracetamol or ibuprofen, with 100 mg to 130 mg caffeine, and the most common pain conditions studied were postoperative dental pain, postpartum pain, and headache." | 8.88 | Caffeine as an analgesic adjuvant for acute pain in adults. ( Derry, CJ; Derry, S; Moore, RA, 2012) |
| "Intravenous ibuprofen or lornoxicam administrations during ischemia reperfusion period in rats have no negative effect on erythrocyte deformability." | 7.83 | Effects of intravenous ibuprofen and lornoxicam on erythrocyte deformability in rats undergoing hind limb ischemia reperfusion injury. ( Alkan, M; Arpaci, H; Arslan, M; Aydin, ME; Comu, FM; Kartal, S; Koc, DS; Kosem, B; Kucuk, A; Ozer, A; Sivgin, V; Turgut, HC, 2016) |
| "Aspirin-sensitive asthma, aspirin-intolerant asthma, aspirin- (or non-steroidal anti-inflammatory drug [NSAID]) exacerbated respiratory disease are terms for a disorder commonly described as affecting adults aged > 30y." | 7.73 | A teenager with severe asthma exacerbation following ibuprofen. ( Palmer, GM, 2005) |
| " Paracetamol has a very flat analgesic dose-response profile." | 7.01 | Analgesic effect of oral ibuprofen 400, 600, and 800 mg; paracetamol 500 and 1000 mg; and paracetamol 1000 mg plus 60 mg codeine in acute postoperative pain: a single-dose, randomized, placebo-controlled, and double-blind study. ( Lyngstad, G; Skjelbred, P; Skoglund, LA; Swanson, DM, 2021) |
| "Tramadol use was reduced significantly in the ibuprofen 400 mg and ibuprofen 800 mg groups compared with the placebo group (P < 0." | 6.87 | A prospective, randomized, double-blind, placebo-controlled trial of acute postoperative pain treatment using opioid analgesics with intravenous ibuprofen after radical cervical cancer surgery. ( Han, F; Liu, X; Wang, X; Wei, L; Zhang, P; Zhao, W, 2018) |
| " The aim of this study was to evaluate the effect of oral ketamine on the dosage of local anesthetics required and postoperative pain management for irreversibly inflamed mandibular molars." | 6.76 | The effect of orally administered ketamine on requirement for anesthetics and postoperative pain in mandibular molar teeth with irreversible pulpitis. ( Ebtehaj, I; Kaviani, N; Khademi, A; Mohammadi, Z, 2011) |
| " The outcome measures of interest in the meta-analysis were ≥ 50% pain relief , need for rescue medications, and occurrence of adverse drug events." | 6.72 | Efficacy and Safety of Ibuprofen Plus Paracetamol in a Fixed-Dose Combination for Acute Postoperative Pain in Adults: Meta-Analysis and a Trial Sequential Analysis. ( Abushanab, D; Al-Badriyeh, D, 2021) |
| " Mean total pain relief and the sum of pain intensity difference were also similar in the early period after dosing (0-4 hours)." | 6.71 | Onset of analgesia and analgesic efficacy of tramadol/acetaminophen and codeine/acetaminophen/ibuprofen in acute postoperative pain: a single-center, single-dose, randomized, active-controlled, parallel-group study in a dental surgery pain model. ( Cha, IH; Jung, YS; Kim, DK; Kim, HJ; Kim, MK; Lee, EW, 2004) |
| "The efficacy of preemptive analgesia on postoperative pain is discussed." | 6.68 | [Preventive analgesic effect of intraoperative administration of ibuprofen-arginine on postmastectomy pain syndrome]. ( Bussières, E; Dixmérias, F; Fonrouge, JM; Lakdja, F; Lobéra, A, 1997) |
| "Ibuprofen is a nonsteroidal antiinflammatory agent with analgesic and antipyretic activity and is an effective, primarily peripheral-acting antiinflammatory analgesic." | 6.68 | Analgesic efficacy of a hydrocodone with ibuprofen combination compared with ibuprofen alone for the treatment of acute postoperative pain. ( Doyle, R; O'Neill, E; Olson, NZ; Ramos, I; Sunshine, A, 1997) |
| "The pharmacological agents approved for treating pain in these patients are few, also considering the recent limitation for codeine in children younger than 12 years." | 6.61 | Ibuprofen in the treatment of children's inflammatory pain: a clinical and pharmacological overview. ( Barbagallo, M; Sacerdote, P, 2019) |
| "This appears to be broadly true in postoperative pain and migraine headache across a range of different drug combinations and when tested in the same and different trials." | 6.52 | Single dose oral ibuprofen plus codeine for acute postoperative pain in adults. ( Derry, S; Karlin, SM; Moore, RA, 2015) |
| "This appears to be broadly true in postoperative pain and migraine headache across a range of different drug combinations, and when tested in the same and different trials." | 6.52 | Single dose oral ibuprofen plus caffeine for acute postoperative pain in adults. ( Derry, S; Moore, RA; Wiffen, PJ, 2015) |
| "This appears to be broadly true in postoperative pain and migraine headache across a range of different drug combinations and when tested in the same and different trials." | 6.49 | Single dose oral ibuprofen plus codeine for acute postoperative pain in adults. ( Derry, S; Karlin, SM; Moore, RA, 2013) |
| "The information from the single trial in acute postoperative pain suggests it to be a useful analgesic, but at doses not very different from racemic ibuprofen." | 6.45 | Single dose oral dexibuprofen [S(+)-ibuprofen] for acute postoperative pain in adults. ( Derry, S; McQuay, HJ; Moore, RA, 2009) |
| "These data do not support the hypothesis that occasional intake of a small dose of caffeine as part of pain medication imposes a health risk due to vital sign changes." | 5.69 | Lack of Evidence for Blood Pressure Effects of Caffeine Added to Ibuprofen. ( Lampert, A; Lange, R; Weiser, T, 2023) |
| "The primary endpoint was the 24-hour postoperative fentanyl consumption, and the secondary endpoints were postoperative modified objective pain score and the incidence of ibuprofen-related side effects (eg, vomiting, epigastric pain, bleeding, and renal dysfunction)." | 5.69 | The Analgesic Effects of the Addition of Intravenous Ibuprofen to a Multimodal Analgesia Regimen for Pain Management After Pediatric Cardiac Surgery: A Randomized Controlled Study. ( Abdelbaser, I; Abo-Zeid, M; Hayes, S; Taman, HI, 2023) |
| "To evaluate the analgesic efficacy and safety of different does of intravenous ibuprofen (IVIB) in the treatment of postoperative acute pain." | 5.69 | Analgesic Efficacy of Intravenous Ibuprofen in the Treatment of Postoperative Acute Pain: A Phase III Multicenter Randomized Placebo-ControlledDouble-Blind Clinical Trial. ( Li, TT; Liu, F; Pi, Y; Wang, TH; Xiong, LL; Zhou, HS, 2023) |
| " We sought to evaluate the effectiveness and safety of over the counter dosing of ibuprofen on pain and bleeding rates following ESS." | 5.56 | Effect of Over the Counter Ibuprofen Dosing after Sinus Surgery for Chronic Rhinosinusitis: A Prospective Cohort Pilot Study. ( Davis, GE; Humphreys, IM; Miller, C, 2020) |
| " Moreover, night administration of ibuprofen might not provide any significant benefits in terms of pain management and control of inflammation, and two doses during the day only could be sufficient for pain management after surgical interventions." | 5.51 | NSAID chronotherapy after impacted third molar extraction: a randomized controlled trial. ( Abusamak, M; Al Habashneh, R; Al-Nusair, M; Al-Tamimi, M; Al-Waeli, H; Gao, Q; Ghanim, M; Nicolau, B; Tamimi, F; Tamimi, Z, 2022) |
| "This study aims to evaluate the efficacy and safety of multiple or single-dosage intravenous ibuprofen (IVIB) in managing postoperative pain and fever in adults who are unable to take oral medications." | 5.41 | Intravenous ibuprofen in postoperative pain and fever management in adults: A systematic review and meta-analysis of randomized controlled trials. ( Chen, L; He, L; Tian, S; Wang, E; Zhai, S; Zhou, P, 2023) |
| "This study aimed to conduct a randomized prospective study about the efficacy of etodolac and ibuprofen on trismus, pain and edema regarding gender of patients submitted to impacted lower third molar teeth extraction." | 5.41 | The efficacy of etodolac and ibuprofen, regarding gender, on pain, edema and trismus after impacted lower third molar surgery: A randomized prospective clinical split-mouth study. ( Farnezi Bassi, AP; Faverani, LP; Reis, EN; Silva, LD, 2021) |
| "To compare the overnight maximum pain scores after osmotic dilator placement prior to a dilation and evacuation (D&E) procedure in participants assigned to a prescription for ibuprofen alone or to ibuprofen plus oxycodone." | 5.41 | Opioid prescription for pain after osmotic dilator placement in abortion care: A randomized controlled trial. ( McAllister, A; Nagendra, D; Roe, AH; Sammel, MD; Schreiber, CA; Schurr, D; Shorter, JM; Sonalkar, S, 2021) |
| "We did not find any statistically significant difference among CYP2C9 phenotypes related to ibuprofen response, although CYP2C9 poor metabolizers had a longer effect (higher pain relief at 6 hours)." | 5.41 | Influence of Genetic Polymorphisms on the Response to Tramadol, Ibuprofen, and the Combination in Patients With Moderate to Severe Pain After Dental Surgery. ( Abad-Santos, F; Acero, J; Borobia, AM; Burgueño, M; Cabaleiro, T; Carcas, AJ; Gálvez-Múgica, MÁ; Llanos, L; Martínez-Pérez, D; Muñoz-Guerra, MF; Ochoa, D; Puerro, M; Saiz-Rodríguez, M; Valdez-Acosta, S, 2021) |
| "This randomized controlled clinical trial aimed to evaluate the preemptive effects of acetaminophen, ibuprofen, ketoprofen, nimesulide or dexamethasone on postoperative pain and edema in the surgical removal of impacted third molars." | 5.41 | Postoperative pain and edema control following different protocols of preemptive analgesia in the surgical removal of impacted third molars: A triple-blind parallel randomized placebo-controlled clinical trial. ( Araújo, AVA; Costa, FO; Cota, LOM; Cyrino, RM; Pinto Júnior, AAC; Santos, BFE, 2021) |
| "Postprocedural pain scores and the number of patients who had increased abdominal pain after the procedure were significantly lower in the IV ibuprofen group." | 5.34 | IV Ibuprofen for Prevention of Post-ERCP Pancreatitis in Children: A Randomized Placebo-controlled Feasibility Study. ( Barth, BA; Gurram, B; Huang, R; Troendle, DM, 2020) |
| " Eligible patients (male and female subjects, aged 18-65 years, reporting pain intensity levels ≥40 mm on a 100-mm visual analog scale (VAS) after distal, first metatarsal bunionectomy) were randomized (3:3:3:2) to receive the FDC (ibuprofen 300 mg + acetaminophen 1000 mg), ibuprofen 300 mg, acetaminophen 1000 mg, or placebo (vehicle), administered as 15-minute intravenous infusions every 6 hours for 48 hours." | 5.30 | Efficacy and Safety of an Intravenous Acetaminophen/Ibuprofen Fixed-dose Combination After Bunionectomy: a Randomized, Double-blind, Factorial, Placebo-controlled Trial. ( Atkinson, HC; Daniels, SE; Gottlieb, IJ; Playne, R; Stanescu, I; Zhang, J, 2019) |
| "To compare the incidence of postoperative pain of chronic periapical periodontitis patients with root canal therapy between Han and Uygur, and the effect of ibuprofen in reducing endodontic flare-up after single-visit root canal therapy between Uyghur and Han patients with chronic apical periodontitis, in order to provide a basis for clinical administration." | 5.24 | [Comparison of the differences in pain and the effect of ibuprofen in reducing endodontic flare-up after single-visit root canal therapy between Uyghur and Han patients with chronic apical periodontitis]. ( Wan, N; Wang, XY; Wu, PL; Yan, L, 2017) |
| "The combination of ibuprofen/paracetamol, taken immediately after initial endodontic therapy and root canal preparation in teeth with irreversible pulpitis, reduced post-endodontic pain (ClinicalTrials." | 5.22 | Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain. ( Abubakr, NH; Elzaki, WM; Ibrahim, YE; Ziada, HM, 2016) |
| "To compare the efficacy of ibuprofen (IBU) and etodolac (ETO) for controlling pain, edema, and trismus after extraction of lower third molars." | 5.22 | Comparative Assessment of the Effect of Ibuprofen and Etodolac on Edema, Trismus, and Pain in Lower Third Molar Surgery: A Randomized Clinical Trial. ( Bassi, AP; Grossi de Oliveira, GA; Silva de Oliveira, JC, 2016) |
| " The aim of this study was to compare the effect on pain relief of on-demand versus regular prescription of ibuprofen after single-visit root canal treatment in teeth with irreversible pulpitis." | 5.19 | Comparison between prescription of regular or on-demand ibuprofen on postoperative pain after single-visit root canal treatment of teeth with irreversible pulpitis. ( Abbott, PV; Manochehrifar, H; Nakhaee, N; Parirokh, M; Sadr, S, 2014) |
| " In this double-blind clinical trial, 100 patients who had anterior or premolar teeth with irreversible pulpitis without any signs and symptoms of acute or chronic apical periodontitis and moderate to severe pain were divided by balanced block random allocation into four groups of 25 each, a control group receiving a placebo medication, and three experimental groups receiving a single dose of either Tramadol (100 mg), Novafen (325 mg of paracetamol, 200 mg ibuprofen and 40 mg caffeine anhydrous) or Naproxen (500 mg) immediately after the first appointment where the pulp was removed, and the canals were fully prepared." | 5.16 | Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial. ( Abbott, PV; Asgar, K; Delvarani, A; Karamifar, K; Khabazi, H; Kharazifard, MJ; Lotfi, M; Mehrvarzfar, P; Saghiri, MA, 2012) |
| "Patients who received bupivacaine as the anesthetic agent for single-visit endodontic treatment of irreversible pulpitis in mandibular molars had significantly less early postoperative pain and used fewer analgesics than those who had lidocaine as the anesthetic." | 5.16 | Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis. ( Abbott, PV; Manochehrifar, H; Nakhaee, N; Parirokh, M; Reza Forghani, F; Yosefi, MH, 2012) |
| "This double-blind, randomized controlled study evaluated etoricoxib (90 and 120 mg), ibuprofen (600 mg), and acetaminophen (600 mg/codeine) (60 mg, (A/C)) in patients aged ≥ 18 years with moderate or severe pain after surgical extraction of ≥ 2 third molars (≥ 1 impacted)." | 5.15 | Evaluation of the dose range of etoricoxib in an acute pain setting using the postoperative dental pain model. ( Bandy, DP; Boice, J; Christensen, SE; Daniels, SE; Liu, H; Losada, MC; Mehta, A; Peloso, PM, 2011) |
| "One hundred and three cases of postopterative pain and 60 cases of fever, altogether 163 patients were randomly divided into 2 groups: S (+) -ismer of ibuprofen supporsitory treatment group (one supporsitory per day for 3 days) and ibuprofen supporsitory treatment group (one supporsitory per day for 3 days)." | 5.11 | [Randomized controlled study of S (+) -ismer of ibuprofen supporsitory]. ( Gao, JS; Huang, AL; Luo, H; Wu, CL; You, YH, 2004) |
| "In a double-blind, placebo-controlled study, 100 patients scheduled for elective termination of pregnancy were randomised to receive placebo, oral ibuprofen 400 mg, oral dextromethorphan 120 mg, or a combination of ibuprofen 400 mg and dextromethorphan 120 mg, 1 h before surgery." | 5.09 | The effect of dextromethorphan, alone or in combination with ibuprofen, on postoperative pain after minor gynaecological surgery. ( Bach, LF; Dahl, JB; Ilkjaer, S; Nielsen, PA; Wernberg, M, 2000) |
| " The authors compare the effectiveness of a single intravenous dose of ketorolac with a single oral dose of either acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus." | 5.07 | Ketorolac versus acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus. ( Morrison, NA; Repka, MX, 1994) |
| "To compare carbon dioxide and nitrous oxide pneumoperitoneum with respect to intraoperative and postoperative pain during laparoscopic sterilization under local anesthesia." | 5.07 | The effect of nitrous oxide and carbon dioxide pneumoperitoneum on operative and postoperative pain during laparoscopic sterilization under local anesthesia. ( Ling, FW; Lipscomb, GH; McCord, ML; Summitt, RL, 1994) |
| " The earlier review included 20 studies (7238 participants) in valid comparisons, but because we used different outcomes for some headache studies, the number of participants in the analyses of the effects of caffeine is now 4262 when previously it was 5243." | 4.90 | Caffeine as an analgesic adjuvant for acute pain in adults. ( Derry, CJ; Derry, S; Moore, RA, 2014) |
| " Most studies used paracetamol or ibuprofen, with 100 mg to 130 mg caffeine, and the most common pain conditions studied were postoperative dental pain, postpartum pain, and headache." | 4.88 | Caffeine as an analgesic adjuvant for acute pain in adults. ( Derry, CJ; Derry, S; Moore, RA, 2012) |
| "The inclusion criteria used were: full journal publication, postoperative pain, postoperative oral administration, adult patients, baseline pain of moderate to severe intensity, double-blind design, and random allocation to treatment groups which compared either ibuprofen or diclofenac with placebo." | 4.80 | Single dose oral ibuprofen and diclofenac for postoperative pain. ( Collins, SL; Edwards, JE; McQuay, HJ; Moore, RA; Wiffen, PJ, 2000) |
| " Patients were advised to use acetaminophen and ibuprofen, and were provided with a small "rescue" opioid prescription for breakthrough pain." | 3.91 | Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway. ( Brummett, C; Englesbe, M; Hallway, A; Howard, R; Lee, J; Palazzolo, W; Vu, J; Waljee, J, 2019) |
| "Intravenous ibuprofen or lornoxicam administrations during ischemia reperfusion period in rats have no negative effect on erythrocyte deformability." | 3.83 | Effects of intravenous ibuprofen and lornoxicam on erythrocyte deformability in rats undergoing hind limb ischemia reperfusion injury. ( Alkan, M; Arpaci, H; Arslan, M; Aydin, ME; Comu, FM; Kartal, S; Koc, DS; Kosem, B; Kucuk, A; Ozer, A; Sivgin, V; Turgut, HC, 2016) |
| "Aspirin-sensitive asthma, aspirin-intolerant asthma, aspirin- (or non-steroidal anti-inflammatory drug [NSAID]) exacerbated respiratory disease are terms for a disorder commonly described as affecting adults aged > 30y." | 3.73 | A teenager with severe asthma exacerbation following ibuprofen. ( Palmer, GM, 2005) |
| "Facial swelling and trismus were also measured at baseline, 24, and 72 h postoperatively." | 3.30 | Effect of time-dependent ibuprofen administration on the post operatory after impacted third molar extraction: a cross-over randomized controlled trial. ( Abusamak, M; García-Denche, JT; Marino, FAT; Pérez-González, F; Sáez-Alcaide, LM, 2023) |
| "Standardized postoperative pain medication including Ibuprofen, Acetaminophen, and narcotics were given as needed." | 3.30 | A randomized, placebo-controlled study of magnetic acupuncture for supplementary analgesia after laparoscopic appendectomy in children. ( Feng, H; König, J; König, T; Muensterer, O, 2023) |
| "The efficacy of trypsin-chymotrypsin in postoperative pain management following single-visit root canal treatment of teeth with symptomatic irreversible pulpitis was evaluated." | 3.30 | The Effect of Trypsin-Chymotrypsin on Postoperative Pain after Single Visit Endodontic Treatment: A Randomized Controlled Trial. ( Abd El Sattar, AA; Abdel Rahman, TY; Hashem, AAR, 2023) |
| "The primary outcome measure was postoperative pain intensity on movement measured by an 11-point NRS (where 0 = no pain and 10 = worst pain imaginable) on POD 1." | 3.30 | Additive or synergistic analgesic effect of metamizole on standard pain treatment at home after arthroscopic shoulder surgery: A randomised controlled superiority trial. ( Callebaut, I; Dreesen, I; Evers, S; Herbots, J; Lambrechts, M; Ory, JP; Stessel, B; Van de Velde, M; Vanderstappen, C; Vaninbroukx, M, 2023) |
| " No drug-related adverse events were reported." | 3.30 | A Multi-Center Evaluation of the Pharmacokinetics and Safety of Intravenous Ibuprofen in Infants 1-6 Months of Age. ( Berkenbosch, JW; Gibson, BHY; Glover, CD; Kaelin, B; Patel, NV; Taylor, MB; Zhong, J, 2023) |
| "Test drugs provided a reduction in postoperative pain scores and lower use of rescue medication when compared to placebo." | 3.30 | Preemptive effects of etoricoxib, acetaminophen, nimesulide, and ibuprofen on postoperative pain management after single-implant surgery: A randomized clinical trial. ( Alvarenga-Brant, R; Costa, FO; Cota, LOM; Esteves-Lima, RP; Mattos-Pereira, GH, 2023) |
| "Postoperative pain was reduced at 24 hours with one dose, and at 48 hours with two doses, of dexamethasone." | 3.11 | Effect of dexamethasone as an analgesic adjuvant to multimodal pain treatment after total knee arthroplasty: randomised clinical trial. ( Ammitzboell, M; Bagger, J; Brorson, S; Gasbjerg, KS; Hägi-Pedersen, D; Holmqvist, M; Jakobsen, JC; Jakobsen, K; Jensen, MS; Laursen, CC; Lindberg-Larsen, M; Lindholm, P; Lunn, TH; Mathiesen, O; Nørskov, AK; Overgaard, S; Pallesen, MJ; Pedersen, NA; Schrøder, HM; Thybo, KH; Vinstrup, LØ, 2022) |
| "IV tramadol infusion was administered with a Patient Controlled Analgesia device for postoperative analgesia." | 3.11 | Efficacy of Intravenous Ibuprofen and Intravenous Paracetamol in Multimodal Pain Management of Postoperative Pain After Percutaneous Nephrolithotomy. ( Aydogan, MS; Colak, YZ; Erdogan, MA; Ozgul, U; Sanlı, M; Ucar, M; Yucel, A, 2022) |
| "The present study aimed to evaluate the postoperative pain levels and analgesic intake on preemptive versus preventive oral administration of ibuprofen in single visit root canal treatment." | 3.11 | Comparative Evaluation of Preemptive and Preventive Analgesic Effect of Oral Ibuprofen in Single Visit Root Canal Treatment- A Prospective Randomised Pilot Study. ( Ramesh, S; Teja, KV; Vasundhara, KA, 2022) |
| "Further, counseling patients on postoperative pain before surgery can reduce the total number of postoperative narcotic and non-narcotic medications taken." | 3.11 | A prospective randomized study evaluating the necessity of narcotics following ureteroscopy for urinary stone disease. ( Atallah, W; Bamberger, JN; Chandhoke, RA; Gallante, B; Gupta, M; Khusid, JA; Sadiq, A; Shimonov, R; Yaghoubian, A; Zampini, AM, 2022) |
| "The secondary outcome measures were postoperative pain score, the incidence of early postoperative fever and the incidence of ibuprofen and ketorolac adverse effects including pain during drug infusion, vomiting, epigastric pain and allergic reaction." | 3.11 | Comparison of intravenous ibuprofen versus ketorolac for postoperative analgesia in children undergoing lower abdominal surgery: A randomized, controlled, non-inferiority study. ( Abdelbaser, I; ALseoudy, MM; El-Emam, EM; Mageed, NA, 2022) |
| " Paracetamol has a very flat analgesic dose-response profile." | 3.01 | Analgesic effect of oral ibuprofen 400, 600, and 800 mg; paracetamol 500 and 1000 mg; and paracetamol 1000 mg plus 60 mg codeine in acute postoperative pain: a single-dose, randomized, placebo-controlled, and double-blind study. ( Lyngstad, G; Skjelbred, P; Skoglund, LA; Swanson, DM, 2021) |
| "Efficacy and rapid onset of postsurgical oral pain relief are critical to improve clinical outcomes and reduce the risk of excessive dosing with analgesic drugs." | 3.01 | COMPARATIVE ANALGESIC EFFECTS OF SINGLE-DOSE PREOPERATIVE ADMINISTRATION OF PARACETAMOL (ACETAMINOPHEN) 500 mg PLUS CODEINE 30 mg AND IBUPROFEN 400 mg ON PAIN AFTER THIRD MOLAR SURGERY. ( Annibali, S; Cristalli, MP; La Monaca, G; Polimeni, A; Pompa, G; Pranno, N; Vozza, I, 2021) |
| "Preventive analgesia aims to manage postoperative pain caused by nociceptive and central stimulation." | 3.01 | Using Intravenous Ibuprofen for Preventive Analgesia in Orthognathic Surgery. ( Canpolat, DG; Demirbaş, AE; Kaba, YN; Yaşlı, SO, 2021) |
| "Effective postoperative pain management after lumbar disc surgery reduces complications and improves postoperative care." | 3.01 | Efficacy of Intravenous Paracetamol and Ibuprofen on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery: Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial. ( Akbas, S; Durak, MA; Ozkan, AS; Yologlu, S, 2021) |
| "Ibuprofen is an effective analgesic for postoperative pain relief in children undergoing primary tooth extraction." | 3.01 | Comparison of preemptive ibuprofen, acetaminophen, and placebo administration in reducing peri- and postoperative pain in primary tooth extraction: A randomized clinical trial. ( Raslan, N; Zouzou, T, 2021) |
| "Independent of postoperative pain management, patients developed significant pain up to the day 4 following surgery." | 3.01 | Does ibuprofen, prednisolone, or amoxicillin reduce post-tonsillectomy pain in children? A prospective randomized controlled trial. ( Anselmo-Lima, WT; Caetano, JVB; Carenzi, LR; de Azevedo, CB; Küpper, DS; Queiroz, DLC; Tamashiro, E; Valera, FCP, 2021) |
| " Adverse event data was collected throughout the study, in addition to scheduled vital sign assessments, laboratory tests and electrocardiograms." | 3.01 | Extending the safety profile of the post-operative administration of an intravenous acetaminophen/ibuprofen fixed dose combination: An open-label, multi-center, single arm, multiple dose study. ( Atkinson, H; Carson, S; Gilchrist, N; Gottlieb, IJ; Stanescu, I, 2021) |
| "A more extensive postoperative pain regimen than paracetamol, ibuprofen and opioids may be needed for a large proportion of patients having total hip arthroplasty." | 3.01 | Participants with mild, moderate, or severe pain following total hip arthroplasty. A sub-study of the PANSAID trial on paracetamol and ibuprofen for postoperative pain treatment. ( Hägi-Pedersen, D; Issa, LM; Jakobsen, JC; Mathiesen, O; Overgaard, S; Thybo, KH; Wetterslev, J, 2021) |
| "The evaluation of postoperative pain was performed by another researcher blinded to the groups at 6, 12, 24, and 72 h intervals after treatment." | 2.94 | Comparison of the effect of photobiomodulation therapy and Ibuprofen on postoperative pain after endodontic treatment: randomized, controlled, clinical study. ( Gualberto Júnior, EC; Herkrath, FJ; Marques, AAF; Nunes, EC; Sponchiado Júnior, EC; Suzuki, EH, 2020) |
| "Limiting harm from postoperative pain treatment is important." | 2.94 | The PANSAID randomized clinical trial: A pre-planned 1-year follow-up regarding harm. ( Hägi-Pedersen, D; Mathiesen, O; Overgaard, S; Thybo, KH; Wetterslev, J, 2020) |
| " Time to meaningful pain relief and duration of pain relief were assessed; tolerability was evaluated by adverse events." | 2.94 | Efficacy and Safety of Single and Multiple Doses of a Fixed-dose Combination of Ibuprofen and Acetaminophen in the Treatment of Postsurgical Dental Pain: Results From 2 Phase 3, Randomized, Parallel-group, Double-blind, Placebo-controlled Studies. ( Cruz-Rivera, M; DePadova, E; Kellstein, D; Leyva, R; Muse, D; Paluch, E; Searle, S, 2020) |
| "Ibuprofen is a NSAID that has anti-inflammatory, antipyretic, and analgesic effects." | 2.94 | A Randomized, Placebo-Controlled, Double-Blind Study that Evaluates Efficacy of Intravenous Ibuprofen and Acetaminophen for Postoperative Pain Treatment Following Laparoscopic Cholecystectomy Surgery. ( Celik, EC; Ciftci, B; Ekinci, M; Karakaya, MA; Köse, EA; Ozdenkaya, Y, 2020) |
| "The primary outcome chosen was postoperative pain, which was evaluated using the visual analogue scale (VAS) score recorded by each patient." | 2.90 | Evaluation of the efficacy of celecoxib and ibuprofen on postoperative pain, swelling, and mouth opening after surgical removal of impacted third molars: a randomized, controlled clinical trial. ( Cicciù, M; Isola, G; Matarese, G; Matarese, M; Ramaglia, L, 2019) |
| " Compared with partial responders to ibuprofen (N = 9, required rescue medication within the dosing interval), complete responders (N = 10, no rescue medication) exhibited greater induction of urinary prostaglandin metabolites and serum tumor necrosis factor-α and interleukin 8." | 2.90 | Variability in the Analgesic Response to Ibuprofen Is Associated With Cyclooxygenase Activation in Inflammatory Pain. ( Detre, JA; Farrar, JT; FitzGerald, GA; Giannakopoulos, HE; Granquist, EJ; Grant, GR; Grosser, T; Hersh, EV; Lahens, NF; Lee, HM; Levin, LM; Li, X; Secreto, SA; Theken, KN, 2019) |
| "Ibuprofen is an effective analgesic after tonsillectomy alone or tonsillectomy with adenoidectomy, but concerns remain about whether it increases postoperative hemorrhage." | 2.90 | Comparison of Ibuprofen vs Acetaminophen and Severe Bleeding Risk After Pediatric Tonsillectomy: A Noninferiority Randomized Clinical Trial. ( Bennett, K; Boseley, M; Brigger, M; Cohen, MS; Comins, J; Diercks, GR; Gallagher, TQ; Gaudreau, P; Hartnick, C; Keamy, D; Rogers, D; Setlur, J, 2019) |
| "Average postoperative pain intensity using a numerical rating scale and use of rescue medication were measured in the postanaesthesia care unit (PACU) and on postoperative days (POD) 1 to 3." | 2.90 | Metamizole vs. ibuprofen at home after day case surgery: A double-blind randomised controlled noninferiority trial. ( Boon, M; Buhre, WFFA; Evers, S; Joosten, EA; Ory, JP; Pelckmans, C; Stessel, B; Van de Velde, M; van Kuijk, SMJ; Wyckmans, W, 2019) |
| "Postoperative pain was assessed with visual analog scale (VAS) every hour for the first 12 hs following the surgery." | 2.90 | The effect of pregabalin and ibuprofen combination for pain after third molar surgery. ( Degirmenci, A; Yalcin, E, 2019) |
| "Postoperative pain was recorded using a visual analog scale at 1, 2, 4, 6, 8, 12, and 24 hours within the postoperative period." | 2.90 | Does Single-Dose Preemptive Intravenous Ibuprofen Reduce Postoperative Pain After Third Molar Surgery? A Prospective, Randomized, Double-Blind Clinical Study. ( Alkan, A; Bilge, S; Canpolat, DG; Demirbas, AE; Karakaya, M; Kütük, N, 2019) |
| "Ibuprofen is an effective analgesic treatment with a ceiling effect at doses above 400 mg." | 2.87 | Efficacy and safety of a fixed-dose combination of ibuprofen and caffeine in the management of moderate to severe dental pain after third molar extraction. ( Hegewisch, A; Lange, R; Muse, DD; Richter, E; Weiser, T, 2018) |
| " Anesthesia and surgery delay gastrointestinal tract function and this may therefore decrease bioavailability of drugs taken by mouth." | 2.87 | Absorption of ibuprofen orodispersible tablets in early postoperative phase - a pharmacokinetic study. ( Kokki, H; Kokki, M; Lehtonen, M; Lidsle, HM; Piirainen, A; Ranta, VP, 2018) |
| "Success was defined as no or mild postoperative pain and no use of an opioid-containing escape medication." | 2.87 | What Is the Outcome of an Incision and Drainage Procedure in Endodontic Patients? A Prospective, Randomized, Single-blind Study. ( Beck, M; Beus, H; Drum, M; Fowler, S; Jatana, C; Nusstein, J; Reader, A, 2018) |
| "Postoperative pain was evaluated through visual analogue scale on 12th hour, first, third and seventh days after surgery." | 2.87 | The effect of flurbiprofen oral spray and ibuprofen vs ibuprofen alone on postoperative tonsillectomy pain: An open, randomised, controlled trial. ( Akpınar, M; Coşkun, BU; Erol, ZN; Kaya, KS; Türk, B; Ünsal, Ö, 2018) |
| "Postoperative pain is a frequent cause for delayed discharge following outpatient procedures, including anorectal surgery." | 2.87 | Preemptive Analgesia Decreases Pain Following Anorectal Surgery: A Prospective, Randomized, Double-Blinded, Placebo-Controlled Trial. ( Callas, P; Cataldo, PA; Dominick, T; Jordan, MR; Leahy, DT; Moore, JS; Van Backer, JT, 2018) |
| "We also aimed to compare postoperative pain levels and side effects of the drugs." | 2.87 | Comparison of intravenous ibuprofen and acetaminophen for postoperative multimodal pain management in bariatric surgery: A randomized controlled trial. ( Erdogan Kayhan, G; Kirteke, R; Ozgul, U; Sanli, M; Yologlu, S, 2018) |
| "Tramadol use was reduced significantly in the ibuprofen 400 mg and ibuprofen 800 mg groups compared with the placebo group (P < 0." | 2.87 | A prospective, randomized, double-blind, placebo-controlled trial of acute postoperative pain treatment using opioid analgesics with intravenous ibuprofen after radical cervical cancer surgery. ( Han, F; Liu, X; Wang, X; Wei, L; Zhang, P; Zhao, W, 2018) |
| "Acute pain is a significant burden to the individual and to society." | 2.87 | Analgesic Efficacy of an Acetaminophen/Ibuprofen Fixed-dose Combination in Moderate to Severe Postoperative Dental Pain: A Randomized, Double-blind, Parallel-group, Placebo-controlled Trial. ( Atkinson, HC; Daniels, SE; Frampton, C; Stanescu, I, 2018) |
| "Adequate postoperative pain control in hand surgery is a multifactorial issue affecting patient satisfaction, outcomes, and safety." | 2.87 | Pain Management After Carpal Tunnel Release Surgery: A Prospective Randomized Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone. ( Graham, JG; Ilyas, AM; Matzon, JL; Miller, AJ, 2018) |
| " Blood samples were collected for pharmacokinetic analysis for up to 6 hours after the loading dose." | 2.87 | Analgesic effectiveness, pharmacokinetics, and safety of a paracetamol/ibuprofen fixed-dose combination in children undergoing adenotonsillectomy: A randomized, single-blind, parallel group trial. ( Anderson, BJ; Atkinson, HC; Frampton, C; Playne, R; Stanescu, I, 2018) |
| "Celecoxib was the most effective analgesic of the three studied drugs in controlling postoperative pain after mandibular third molar extraction in our subjects." | 2.87 | Comparative Analgesic Effects of Ibuprofen, Celecoxib and Tramadol after third Molar Surgery: A Randomized Double Blind Controlled Trial. ( Akinbade, AO; Ndukwe, KC; Owotade, FJ, 2018) |
| "No studies have examined postoperative pain control following transsphenoidal surgery for pituitary lesions." | 2.87 | Randomized, double-blinded, placebo-controlled trial comparing two multimodal opioid-minimizing pain management regimens following transsphenoidal surgery. ( Jahnke, H; Little, AS; Shepherd, DM; White, WL, 2018) |
| "Finally, diarrhea was recorded in 5 patients of the antibiotic alone group (18." | 2.84 | Antibiotic treatment to prevent postextraction complications: a monocentric, randomized clinical trial. Preliminary outcomes. ( Barone, A; Cinquini, C; Cipolli Panattoni, A; Covani, U; Gabriele, M; Marchionni, FS; Marconcini, S; Toti, P, 2017) |
| "Postoperative pain was assessed using the visual analog scale (VAS) every 3 hours (while awake) for the first 48 hours after surgery." | 2.84 | Efficacy of Codeine When Added to Paracetamol (Acetaminophen) and Ibuprofen for Relief of Postoperative Pain After Surgical Removal of Impacted Third Molars: A Double-Blinded Randomized Control Trial. ( Best, AD; Cameron, CM; De Silva, HL; De Silva, RK; Thomson, WM; Tong, DC, 2017) |
| "PCA morphine consumption was recorded and postoperative pain was evaluated by Visual Analog Scale (VAS) in postoperative recovery room, at the 1st, 2nd, 4th, 8th, 12th, 24th, 36th, and 48th hours." | 2.84 | Effects of Addition of Preoperative Intravenous Ibuprofen to Pregabalin on Postoperative Pain in Posterior Lumbar Interbody Fusion Surgery. ( Doğan, R; Karaca, Ö; Karakoç, F; Pınar, HU, 2017) |
| "Effective postoperative pain management is essential for the rehabilitation of the surgical patient." | 2.84 | PANSAID-PAracetamol and NSAID in combination: detailed statistical analysis plan for a randomised, blinded, parallel, four-group multicentre clinical trial. ( Bjørck, JG; Bülow, HH; Dahl, JB; Hägi-Pedersen, D; Jakobsen, JC; Mathiesen, O; Overgaard, S; Pedersen, NA; Schrøder, HM; Thybo, KH; Wetterslev, J, 2017) |
| "Mean postoperative pain was lower in the CUI as compared to SI group, but the difference was significant on the first day only (P = 0." | 2.84 | Effect of continuous ultrasonic irrigation on postoperative pain in mandibular molars with nonvital pulps: a randomized clinical trial. ( Duhan, J; Middha, M; Sangwan, P; Tewari, S, 2017) |
| "Postoperative pain is a potential adverse side effect of oral surgeries, and attempts should be made to prevent or minimize it." | 2.84 | Comparison Between Dexamethasone and Ibuprofen for Postoperative Pain Prevention and Control After Surgical Implant Placement: A Double-Masked, Parallel-Group, Placebo-Controlled Randomized Clinical Trial. ( Alasmari, DS; Almas, K; Alzoman, HA; Attia, MS; Bahammam, LA; Bahammam, MA; Hassan, MH; Kayal, RA; Steffens, JP, 2017) |
| "Effective postoperative pain management is essential for the rehabilitation of the surgical patient." | 2.84 | PANSAID - PAracetamol and NSAID in combination: study protocol for a randomised trial. ( Bjørck, JG; Bülow, HH; Dahl, JB; Hägi-Pedersen, D; Mathiesen, O; Schrøder, HM; Thybo, KH; Wetterslev, J, 2017) |
| "Ibuprofen was not associated with an increased rate of PTH (log odds ratio [OR], 0." | 2.82 | Post-Tonsillectomy Ibuprofen: Is There a Dose-Dependent Bleeding Risk? ( Lin, HC; Losorelli, SD; Qian, ZJ; Scheffler, P; Truong, MT, 2022) |
| "Preemptive analgesia may improve postoperative pain management, but the optimal regimen is unclear." | 2.82 | Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis. ( Chin, V; Houle, TT; Li, C; Ma, H; Mueller, A; Wang, D; Wang, J; Xuan, C; Yan, W, 2022) |
| "The aim of this meta-analysis was to assess the analgesic efficacy and adverse effects of celecoxib compared to non-opioid drugs after third molar surgery." | 2.82 | Analgesic effectiveness and safety of celecoxib versus non-opioid active controls after third molar surgery: A meta-analytical evaluation. ( Alonso-Castro, ÁJ; Franco-de la Torre, L; Franco-González, MA; Isiordia-Espinoza, MA, 2022) |
| "Success was defined as no or mild postoperative pain and no use of escape medication." | 2.82 | What is the Effect of No Endodontic Debridement on Postoperative Pain for Symptomatic Teeth with Pulpal Necrosis? ( Beck, M; Drum, M; Fowler, S; Nusstein, J; Reader, A; Sebastian, R, 2016) |
| "IV acetaminophen has also been shown to be effective in alleviating pain for surgical procedures." | 2.82 | A Randomized Trial Comparing the Safety and Efficacy of Intravenous Ibuprofen versus Ibuprofen and Acetaminophen in Knee or Hip Arthroplasty. ( Abubaker, H; Ahrendtsen, L; Demas, E; Gupta, A, 2016) |
| "We found no influence on postoperative pain after high-dose remifentanil in patients undergoing pancreaticoduodenectomy." | 2.82 | Influence of high-dose intraoperative remifentanil with intravenous ibuprofen on postoperative morphine consumption in patients undergoing pancreaticoduodenectomy: a randomized trial. ( Cho, YJ; Hong, DM; Jeon, Y; Kim, TK; Koo, CH, 2016) |
| " Vital signs, adverse events, and pain scores were assessed." | 2.80 | The shortened infusion time of intravenous ibuprofen, part 2: a multicenter, open-label, surgical surveillance trial to evaluate safety. ( Bergese, SD; Buvanendran, A; Candiotti, K; Gan, TJ; Philip, BK; Soghomonyan, S; Turan, A; Viscusi, ER, 2015) |
| "Combined paracetamol and ibuprofen has been shown to be more effective than either constituent alone for acute pain in adults, but the dose-response has not been confirmed." | 2.80 | Combination paracetamol and ibuprofen for pain relief after oral surgery: a dose ranging study. ( Atkinson, HC; Bisley, E; Carson, S; Currie, J; Evans, S; Frampton, C; Moodie, J; Steenberg, LJ; Worthington, JP, 2015) |
| "Peak postoperative pain occurred at 16 hours post-treatment in both groups, there was a significant difference in the pain scale between the two groups in favor for group B over group A (3." | 2.80 | Role of Prophylactic Antibiotics in the Management of Postoperative Endodontic Pain. ( Al Habahbeh, R; Alsomadi, L, 2015) |
| " Intravenous ibuprofen administered at induction of anesthesia may be a safe and efficacious option for postoperative tonsillectomy pain." | 2.79 | A multicenter, randomized, double-blind placebo-controlled, single dose trial of the safety and efficacy of intravenous ibuprofen for treatment of pain in pediatric patients undergoing tonsillectomy. ( Bendel, LP; Glover, CD; McCarthy, DL; Moss, JR; Watcha, MF; Witham, SL, 2014) |
| "60 Miller class I and II gingival recessions (GR) (≥ 3 mm in depth) were treated with the coronally advanced flap plus extraoral de-epithelialized free gingival graft (FGG)." | 2.79 | Does the dimension of the graft influence patient morbidity and root coverage outcomes? A randomized controlled clinical trial. ( Mazzotti, C; Mele, M; Montebugnoli, L; Mounssif, I; Sangiorgi, M; Stefanini, M; Zucchelli, G, 2014) |
| " When comparing all three groups, a statistically significant dose-response relationship was seen for present, average and worst pain intensity after 8 h and on the following morning." | 2.79 | Dexamethasone for pain after outpatient shoulder surgery: a randomised, double-blind, placebo-controlled trial. ( Bjørnholdt, KT; Mønsted, PN; Nikolajsen, L; Søballe, K, 2014) |
| "We compared the intensity of postoperative pain experienced by patients who received conventional open thyroidectomy (n = 45) versus those who underwent robotic thyroidectomy (n = 45)." | 2.78 | A comparison of postoperative pain after conventional open thyroidectomy and transaxillary single-incision robotic thyroidectomy: a prospective study. ( Chung, WY; Hong, JY; Jeong, JJ; Kang, SW; Lee, J; Park, JH; Ryu, HR, 2013) |
| "For the treatment of postoperative pain, 30 patients constituted group F and received a 12." | 2.78 | Postoperative fentanyl patch versus subacromial bupivacaine infusion in arthroscopic shoulder surgery. ( Aantaa, R; Äärimaa, V; Koivisto, M; Kuusniemi, K; Leino, K; Liukas, A; Merivirta, R, 2013) |
| "Optimal postoperative pain management is important to ensure patient comfort and early mobilization." | 2.78 | Evaluation of etoricoxib in patients undergoing total knee replacement surgery in a double-blind, randomized controlled trial. ( Chen, L; Chitkara, DK; Curtis, SP; Mehta, A; Minkowitz, HS; Papanicolaou, DA; Peloso, PM; Rawal, N; Shah, S; Viscusi, E, 2013) |
| "The variables analyzed were postoperative pain through visual analog scale (VAS), total number of rescue analgesic (TNRA), and patient satisfaction." | 2.78 | Assessment of preemptive analgesia with ibuprofen coadministered or not with dexamethasone in third molar surgery: a randomized double-blind controlled clinical trial. ( Bauer, HC; Duarte, FL; Horliana, AC; Jorge, WA; Perez, FE; Simone, JL; Tortamano, IP, 2013) |
| "Each patient was asked to record their postoperative pain on a visual analogue scale with 4 categories at 6 hours, 12 hours, 18 hours, 1 day, and then daily for 6 days after this treatment." | 2.78 | Effect of occlusal reduction on postoperative pain in teeth with irreversible pulpitis and mild tenderness to percussion. ( Abbott, PV; Ashouri, R; Gorjestani, H; Nakhaee, N; Parirokh, M; Rekabi, AR, 2013) |
| "The facial swelling and trismus were evaluated by measuring facial reference distances and maximum mouth opening." | 2.77 | Effect of preoperative ibuprofen on pain and swelling after lower third molar removal: a randomized controlled trial. ( Aznar-Arasa, L; Figueiredo, R; Gay-Escoda, C; Harutunian, K; Valmaseda-Castellón, E, 2012) |
| "Recovery times, postoperative pain scores, and the need for rescue analgesics were recorded before discharge." | 2.76 | The effects of oral ibuprofen and celecoxib in preventing pain, improving recovery outcomes and patient satisfaction after ambulatory surgery. ( Fermelia, DE; Kariger, R; Naruse, R; Sloninsky, A; Tang, J; Time, M; Tsushima, GK; Webb, T; Wender, RH; White, PF; Yumul, R; Zaentz, A; Zhao, M, 2011) |
| "Ibuprofen was significantly more effective than placebo across all endpoints." | 2.76 | A randomized, controlled study to investigate the analgesic efficacy of single doses of the cannabinoid receptor-2 agonist GW842166, ibuprofen or placebo in patients with acute pain following third molar tooth extraction. ( Albanese, M; Bullman, J; Costantin, C; Guillard, F; Leeson, R; Meyer, I; Milleri, S; Nocini, PF; Ostenfeld, T; Price, J; Ziviani, L, 2011) |
| "The ibuprofen dose range was 100-400 mg, and acetaminophen dose range was 500-1000 mg." | 2.76 | Explaining the acetaminophen-ibuprofen analgesic interaction using a response surface model. ( Anderson, BJ; Hannam, J, 2011) |
| " The aim of this study was to evaluate the effect of oral ketamine on the dosage of local anesthetics required and postoperative pain management for irreversibly inflamed mandibular molars." | 2.76 | The effect of orally administered ketamine on requirement for anesthetics and postoperative pain in mandibular molar teeth with irreversible pulpitis. ( Ebtehaj, I; Kaviani, N; Khademi, A; Mohammadi, Z, 2011) |
| " Maxigesic tablets combine acetaminophen and ibuprofen in clinically appropriate doses to simplify administration and dosage regimen." | 2.75 | Combined acetaminophen and ibuprofen for pain relief after oral surgery in adults: a randomized controlled trial. ( Anderson, BJ; Davies, E; Edwards, J; Frampton, C; Gibbs, RD; Merry, AF; Ting, GS, 2010) |
| "Pain, swelling, infection, trismus and temperature were recorded on days 3, 7 and 14 after surgery." | 2.75 | Antibiotic prophylaxis in third molar surgery: A randomized double-blind placebo-controlled clinical trial using split-mouth technique. ( Morkel, JA; Siddiqi, A; Zafar, S, 2010) |
| "To improve the patients postoperative pain experience using protective analgesia for patients undergoing third molar surgery under day case general anaesthesia." | 2.75 | Pain after surgery: can protective analgesia reduce pain? A randomised clinical trial. ( Coulthard, P; Yong, SL, 2010) |
| " AEs were assessed at 8 hours after dosing in stage 1, at 72 hours after dosing in stage 2, and at the follow-up visit (7-10 days after surgery); in addition, patients were instructed to report any AE that occurred between scheduled assessments." | 2.75 | A single-tablet fixed-dose combination of racemic ibuprofen/paracetamol in the management of moderate to severe postoperative dental pain in adult and adolescent patients: a multicenter, two-stage, randomized, double-blind, parallel-group, placebo-control ( Aspley, S; Christensen, KS; Daniels, SE; Mehlisch, DR; Southerden, KA, 2010) |
| "Sodium hypochlorite can cause severe tissue irritation and necrosis outside the root canal system if extruded into the periodontal ligament (PDL) space." | 2.75 | Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial. ( Dos Carmo, CB; Gondim, E; Kim, S; Setzer, FC, 2010) |
| " Mild-to-moderate adverse effects were reported." | 2.74 | A randomized, double-blind, placebo-controlled study comparing the efficacy and safety of paracetamol, serratiopeptidase, ibuprofen and betamethasone using the dental impaction pain model. ( Chopra, D; Kakkar, AK; Mehra, P; Rehan, HS, 2009) |
| "Postoperative pain was assessed during the first 8 hours and on the following day using the 101-point numeric rate scale (NRS-101) and the four-point verbal rating scale (VRS-4)." | 2.74 | The efficacy of acetaminophen-caffeine compared to Ibuprofen in the control of postoperative pain after periodontal surgery: a crossover pilot study. ( Rashwan, WA, 2009) |
| "The ibuprofen and placebo were administered while patients had access to morphine throughout the duration of the study." | 2.74 | A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain. ( Pavliv, L; Peters, J; Rock, A; Southworth, S, 2009) |
| "Levobupivacaine is a valid alternative to traditional local anesthetics for surgical removal of lower third molars." | 2.74 | Postoperative pain relief after surgical removal of impacted third molars: a single-blind, randomized, controlled study to compare levobupivacaine and mepivacaine. ( Brienza, N; Crincoli, V; Di Bisceglie, MB; Favia, G; Giuliani, R; Massaro, M, 2009) |
| "Ibuprofen was consistently better than acetaminophen at 1 hour after treatment for relief of perineal pain after childbirth without any side effects." | 2.73 | Ibuprofen versus acetaminophen for the relief of perineal pain after childbirth: a randomized controlled trial. ( Kamondetdecha, R; Tannirandorn, Y, 2008) |
| "Tapentadol is a novel, centrally acting analgesic with two modes of action, combining mu-opioid agonism and norepinephrine reuptake inhibition in a single molecule." | 2.73 | Single dose analgesic efficacy of tapentadol in postsurgical dental pain: the results of a randomized, double-blind, placebo-controlled study. ( Black, P; Desjardins, P; Goldberg, J; Kleinert, R; Lange, C; Steup, A, 2008) |
| "Dexamethasone is widely used to prevent postoperative nausea and vomiting (PONV) in pediatric tonsillectomy." | 2.73 | Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial. ( Czarnetzki, C; Desmeules, J; Dulguerov, P; Dumont, L; Elia, N; Giger, R; Landis, BN; Lysakowski, C; Tramèr, MR, 2008) |
| "To determine whether postoperative pain/distress in the early recovery period was different for those children who did or did not have local infiltration anaesthesia for extractions under general anaesthetic, and whether the incidence of clinically significant postoperative bleeding was different for the two groups." | 2.73 | Assessment of early postoperative pain and haemorrhage in young children undergoing dental extractions under general anaesthesia. ( McWilliams, PA; Rutherford, JS, 2007) |
| "The ibuprofen level was determined in all cerebrospinal fluid and plasma samples." | 2.73 | Cerebrospinal fluid distribution of ibuprofen after intravenous administration in children. ( Heikkinen, M; Kokki, H; Kumpulainen, E; Laisalmi, M; Lehtonen, M; Rautio, J; Savolainen, J, 2007) |
| "Postoperative pain was assessed using a visual analog scale (VAS)." | 2.73 | Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures. ( Tatakis, DN; Wessel, JR, 2008) |
| "No significant differences in postoperative pain levels were found between either single-dose ibuprofen formulation or the placebo control group (P = ." | 2.73 | Evaluation of pretreatment analgesia and endodontic treatment for postoperative endodontic pain. ( Attar, S; Baisden, MK; Bowles, WR; Hodges, JS; McClanahan, SB, 2008) |
| " The outcome measures of interest in the meta-analysis were ≥ 50% pain relief , need for rescue medications, and occurrence of adverse drug events." | 2.72 | Efficacy and Safety of Ibuprofen Plus Paracetamol in a Fixed-Dose Combination for Acute Postoperative Pain in Adults: Meta-Analysis and a Trial Sequential Analysis. ( Abushanab, D; Al-Badriyeh, D, 2021) |
| "The studies evaluated patients' postoperative pain by either utilizing a visual analogue scale (VAS), measuring the time between surgery and when rescue analgesics were used, measuring the amount of rescue analgesics used, or by distributing questionnaires." | 2.72 | Pharmacological and Non-Pharmacological Methods of Postoperative Pain Control Following Oral and Maxillofacial Surgery: A Scoping Review. ( Elmowitz, JS; Shupak, RP, 2021) |
| "In addition to providing acute postoperative pain relief, preoperative PVB seems to reduce the prevalence of chronic pain 1 yr after breast cancer surgery." | 2.72 | Preincisional paravertebral block reduces the prevalence of chronic pain after breast surgery. ( Bachmann, MS; Kairaluoma, PM; Pere, PJ; Rosenberg, PH, 2006) |
| "Ibuprofen was significantly better at reducing pain at all time intervals by comparison with the placebo." | 2.72 | Ibuprofen as a pre-emptive analgesic is as effective as rofecoxib for mandibular third molar surgery. ( Kevelham, E; Morse, Z; Tump, A, 2006) |
| "Only a relatively short immediate analgesic benefit could be demonstrated by a combination of IINB with spinal anaesthesia compared with IINB combined with general anaesthesia." | 2.71 | Analgesia and discharge following preincisional ilioinguinal and iliohypogastric nerve block combined with general or spinal anaesthesia for inguinal herniorrhaphy. ( Permi, J; Rosenberg, PH; Toivonen, J, 2004) |
| "Which isoform of COX is responsible for postsurgical pain and, consequently, should be targeted, is unclear." | 2.71 | Spinal prostaglandin formation and pain perception following thoracotomy: a role for cyclooxygenase-2. ( Fitzgerald, D; McCrory, C, 2004) |
| "midazolam treatment (0." | 2.71 | Sedation with midazolam leads to reduced pain after dental surgery. ( Ong, CK; Seymour, RA; Tan, JM, 2004) |
| " Mean total pain relief and the sum of pain intensity difference were also similar in the early period after dosing (0-4 hours)." | 2.71 | Onset of analgesia and analgesic efficacy of tramadol/acetaminophen and codeine/acetaminophen/ibuprofen in acute postoperative pain: a single-center, single-dose, randomized, active-controlled, parallel-group study in a dental surgery pain model. ( Cha, IH; Jung, YS; Kim, DK; Kim, HJ; Kim, MK; Lee, EW, 2004) |
| " Based on these data, the following primary efficacy end points were determined: total pain relief 6 hours after dosing (TOTPAR6) and sum of pain intensity differences 6 hours after dosing (SPID6)." | 2.71 | Combination oxycodone 5 mg/ibuprofen 400 mg for the treatment of pain after abdominal or pelvic surgery in women: a randomized, double-blind, placebo- and active-controlled parallel-group study. ( Newman, K; Pong, A; Singla, N, 2005) |
| "Postoperative pain was treated with intravenous piritramide (opioid receptor agonist with analgesic potency of 0." | 2.71 | Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study. ( Dinse, M; Hermsen, M; Lehmann, C; Pavlovic, D; Usichenko, TI; Witstruck, T, 2005) |
| "As part of ongoing studies to evaluate the analgesic efficacy and pharmacokinetic properties of combination oxycodone plus ibuprofen in the treatment of moderate to severe acute pain, 2 pharmacokinetic studies were conducted." | 2.71 | Pharmacokinetic properties of combination oxycodone plus racemic ibuprofen: two randomized, open-label, crossover studies in healthy adult volunteers. ( Abramowitz, W; Benedek, I; Fiske, W; Kapil, R; Nolting, A; Roy, P, 2004) |
| " The primary outcome measures were total pain relief through 6 hours after dosing (TOTPAR6), sum of pain intensity differences through 6 hours (SPID6), and adverse events." | 2.71 | Analgesic efficacy and tolerability of oxycodone 5 mg/ibuprofen 400 mg compared with those of oxycodone 5 mg/acetaminophen 325 mg and hydrocodone 7.5 mg/acetaminophen 500 mg in patients with moderate to severe postoperative pain: a randomized, double-blin ( Adamson, DN; Christensen, SE; Han, SH; Litkowski, LJ; Newman, KB; Van Dyke, T, 2005) |
| "Ibuprofen liquigel is an encapsulated, solubilized potassium salt of ibuprofen that has a higher Cmax and shorter tmax than traditional ibuprofen solid-dosage formulations." | 2.70 | Efficacy and tolerability of nonprescription ibuprofen versus celecoxib for dental pain. ( Ashraf, E; Cooper, SA; Doyle, G; Jayawardena, S, 2002) |
| "Ibuprofen arginate was effective in this population of patients experiencing moderate to severe pain after surgical extraction of > or = 1 impacted third molar, with 16 to 24 minutes' faster time to meaningful pain relief than with ibuprofen." | 2.70 | A randomized, double-blind, placebo-controlled comparison of the analgesic efficacy, onset of action, and tolerability of ibuprofen arginate and ibuprofen in postoperative dental pain. ( Ardia, A; Black, P; Desjardins, P; Max, MB; Norwood, T; Pallotta, T, 2002) |
| "Ibuprofen is a safe and effective analgesic, but some formulations have a slow onset of action." | 2.70 | Ibuprofen arginate provides effective relief from postoperative dental pain with a more rapid onset of action than ibuprofen. ( Ardia, A; Black, P; Desjardins, P; Norris, L; Norwood, T; Papageorge, M; Shen, DD, 2002) |
| "Ibuprofen is a peripherally acting nonsteroidal anti-inflammatory drug indicated fo ranalgesia, antipyresis, and various arthritic conditions." | 2.70 | Onset of analgesia for liquigel ibuprofen 400 mg, acetaminophen 1000 mg, ketoprofen 25 mg, and placebo in the treatment of postoperative dental pain. ( Cooper, S; Doyle, G; Jayawardena, S; Marrero, I; Olson, NZ; Otero, AM; Sunshine, A; Tirado, S, 2001) |
| "This study evaluated trismus, bite force, and pressure algometry as measures of analgesic efficacy after third molar removal." | 2.69 | Evaluation of trismus, bite force, and pressure algometry after third molar surgery: a placebo-controlled study of ibuprofen. ( Aagaard, E; Nørholt, SE; Sindet-Pedersen, S; Svensson, P, 1998) |
| "The purpose of this single-dose, randomized, placebo-controlled, and double-blind study was to evaluate the analgesic dose-response relationship of 50-mg, 100-mg, 200-mg, and 400-mg doses of ibuprofen after third molar surgery." | 2.69 | Analgesic dose-response relationship of ibuprofen 50, 100, 200, and 400 mg after surgical removal of third molars: a single-dose, randomized, placebo-controlled, and double-blind study of 304 patients. ( Branebjerg, PE; Bugge, C; Hillerup, S; Nattestad, A; Nielsen, H; Ritzau, M; Schou, S; Skoglund, LA, 1998) |
| "Acetaminophen with codeine was more effective in controlling pain on days 1 and 3 (p = 0." | 2.69 | Ibuprofen for tonsillectomy pain in children: efficacy and complications. ( Dattolo, RA; Harley, EH, 1998) |
| "Ibuprofen 400 mg was significantly superior to placebo for pain relief (P < 0." | 2.69 | The comparative efficacy of aceclofenac and ibuprofen in postoperative pain after third molar surgery. ( Frame, J; Hawkesford, JE; Marsden, J; Matthew, IR; Negus, TW; Seymour, RA, 1998) |
| " Patients had access to escape analgesic and if these were taken, the time and dosage were recorded." | 2.69 | The efficacy of a novel adenosine agonist (WAG 994) in postoperative dental pain. ( Andrews, C; Frame, J; Hawkesford, JE; Hill, CM; Seymour, RA, 1999) |
| "The objective of this study was to demonstrate a dose-response effect with 1- and 2-tablet doses of combination hydrocodone 7." | 2.69 | Dose-response effect of combination hydrocodone with ibuprofen in patients with moderate to severe postoperative pain. ( Damask, M; de Padova, A; Doyle, RT; Jiang, JG; Keffer, M; Landau, CJ; Morris, E; Palangio, M; Wideman, GL, 2000) |
| "Ibuprofen was apparently adequate in controlling pain for 147 out of 161 patients but on further questioning 42 of these patients took supplemental analgesics and self-prescribed paracetamol or a paracetamol combination." | 2.69 | Pain control after routine dento-alveolar day surgery: a patient satisfaction survey. ( Joshi, A; Rood, JP; Snowdon, AT; Worthington, HV, 2000) |
| "Ibuprofen liquigel is a solubilized potassium ibuprofen 200-mg gelatin capsule formulation that was approved for over-the-counter use in 1995." | 2.69 | Ibuprofen liquigel for oral surgery pain. ( Cooper, SA; Doyle, G; Hersh, EV; Hong, D; Levin, LM; Secreto, SA; Waksman, J; Wedell, D, 2000) |
| " A dose-response relationship was observed for ketoprofen, with the two higher doses providing significantly greater analgesia than the lower dose." | 2.69 | Onset and duration of analgesia for low-dose ketoprofen in the treatment of postoperative dental pain. ( Marrero, I; Olson, NZ; Sunshine, A; Tirado, S, 1998) |
| "The efficacy of preemptive analgesia on postoperative pain is discussed." | 2.68 | [Preventive analgesic effect of intraoperative administration of ibuprofen-arginine on postmastectomy pain syndrome]. ( Bussières, E; Dixmérias, F; Fonrouge, JM; Lakdja, F; Lobéra, A, 1997) |
| "05) were observed between efficacy measures and the various pharmacokinetic parameters (AUC0-300, Cmax and Tmax) for ibuprofen after the soluble dose." | 2.68 | Are the pharmacokinetics of ibuprofen important determinants for the drug's efficacy in postoperative pain after third molar surgery? ( Hawkesford, JE; Jones, K; Seymour, RA, 1997) |
| "Postoperative pain was assessed using the Children's Hospital of Eastern Ontario Pain Scale (CHEOPS) upon arrival to the PACU and at 5, 10, 15, 30, 45, and 60 min." | 2.68 | Postoperative analgesia with preoperative oral ibuprofen or acetaminophen in children undergoing myringotomy. ( Allen, H; Bennie, RE; Boehringer, LA; Dierdorf, SF; McMahon, S, 1997) |
| "Ibuprofen is a nonsteroidal antiinflammatory agent with analgesic and antipyretic activity and is an effective, primarily peripheral-acting antiinflammatory analgesic." | 2.68 | Analgesic efficacy of a hydrocodone with ibuprofen combination compared with ibuprofen alone for the treatment of acute postoperative pain. ( Doyle, R; O'Neill, E; Olson, NZ; Ramos, I; Sunshine, A, 1997) |
| "Ibuprofen was significantly better than all other treatments for all measures of analgesic activity." | 2.67 | Clinical evaluation of H1-receptor and H2-receptor antagonists for acute postoperative pain. ( Berthold, CW; Dionne, RA, 1993) |
| " A positive dose-response was seen for both active drugs with meclofenamate 100 mg and ibuprofen 400 mg exhibiting the greatest efficacy for pain relief, pain reduction, time to remedication, and overall evaluation." | 2.67 | Single dose and multidose analgesic study of ibuprofen and meclofenamate sodium after third molar surgery. ( Bergman, S; Betts, N; Cooper, S; Gaston, G; Henry, E; Hersh, EV; Lamp, C; MacAfee, K; Quinn, P; Wedell, D, 1993) |
| "Ibuprofen was significantly more efficacious (p < ." | 2.67 | Narcotic receptor blockade and its effect on the analgesic response to placebo and ibuprofen after oral surgery. ( Barasch, A; Cooper, SA; Hersh, EV; MacAfee, K; Ochs, H; Quinn, P, 1993) |
| "Ibuprofen was significantly better than codeine only through hour 3." | 2.67 | Ibuprofen controlled-release formulation. A clinical trial in dental impaction pain. ( Cooper, SA; Hersh, EV; Lamp, C; MacAfee, K; Quinn, PD; Sullivan, D, 1993) |
| "Ibuprofen was more effective after one hour than either of the other two drugs, whatever the scale or parameter used." | 2.67 | [Analgesic effect of ibuprofen in pain after episiotomy]. ( Barrat, J; Behotas, S; Boureau, F; Castiel, J; Chauvin, A; Lienhart, A; Martin, A, 1992) |
| " Results indicated that dosing with ibuprofen either immediately before or immediately after periodontal surgery significantly delays onset of pain as compared to placebo, with dosing after surgery demonstrating a significantly greater delay of onset of pain as compared to dosing presurgically." | 2.67 | Comparison of presurgical and immediate postsurgical ibuprofen on postoperative periodontal pain. ( Desjardins, PJ; Major, KV; Vogel, RI, 1992) |
| "The profiles of postoperative pain in the two groups were similar from the first postoperative day, but Ibumetin was better pain reliever on the day of surgery." | 2.67 | Pain control after third molar surgery--a comparative study of ibuprofen (Ibumetin) and a paracetamol/codeine combination (Citodon). ( Anzén, B; Lysell, L, 1992) |
| " This trial design (crossover with multiple dosing in outpatients) is a sensitive way of testing for analgesia, and is potentially more predictive of adverse effect problems than single-dose studies." | 2.67 | A multiple dose comparison of combinations of ibuprofen and codeine and paracetamol, codeine and caffeine after third molar surgery. ( Carroll, D; Guest, P; Juniper, RP; McQuay, HJ; Moore, RA, 1992) |
| " The slope of the dose-response curve of bromfenac was significant." | 2.67 | Analgesic efficacy of bromfenac, ibuprofen, and aspirin in postoperative oral surgery pain. ( Beaver, WT; Edquist, IA; Forbes, JA; Gongloff, CM; Jones, KF; Schwartz, MK; Smith, FG; Smith, WK, 1992) |
| "Postoperative pain was evaluated on the visual analogue scale (VAS) and the 101-point numerical rating scale immediately before the start of the infusion." | 2.67 | [A comparison of a tramadol/metamizole infusion with the combination tramadol infusion plus ibuprofen suppositories for postoperative pain management following hysterectomy]. ( Hackenberger, J; Striebel, HW, 1992) |
| "Seventy-four outpatients with postoperative pain after oral surgery were randomly assigned, on a double-blind basis, to receive a single oral dose of a controlled-release tablet (CRT) containing 600 mg ibuprofen, two 600-mg ibuprofen CRTs, or placebo." | 2.67 | Evaluation of an ibuprofen controlled-release tablet and placebo in postoperative oral surgery pain. ( Allen, HW; Beaver, WT; Forbes, JA; Moore, EM, 1991) |
| " All active treatments were significantly superior to placebo, and the slope of the dose-response curve for bromfenac was significant." | 2.67 | Evaluation of bromfenac, aspirin, and ibuprofen in postoperative oral surgery pain. ( Beaver, WT; Edquist, IA; Forbes, JA; Schwartz, MK; Smith, FG, 1991) |
| "Two-hundred six outpatients with postoperative pain after the surgical removal of impacted third molars were randomly assigned on a double-blind basis to receive oral doses of ketorolac tromethamine 10 and 20 mg, ibuprofen 400 mg, acetaminophen 600 mg, a combination of acetaminophen 600 mg plus codeine 60 mg, or placebo." | 2.67 | Evaluation of ketorolac, ibuprofen, acetaminophen, and an acetaminophen-codeine combination in postoperative oral surgery pain. ( Beaver, WT; Forbes, JA; Grodin, CD; Kehm, CJ, 1990) |
| "Ibuprofen has important implications for postoperative pain in clinical practice." | 2.67 | Multicenter clinical trial of ibuprofen and acetaminophen in the treatment of postoperative dental pain. ( Helfrick, JF; Leibold, DG; Markowitz, R; Mehlisch, DR; Schow, CE; Shultz, R; Sollecito, WA; Waite, DE, 1990) |
| "Ibuprofen was found to be the most effective analgesic in post-episiotomy pain followed by analgin and paracetamol in that order." | 2.67 | A comparison of four analgesics in post-episiotomy pain. ( Agshikar, NV; Bhounsule, SA; Dhume, VG; Nevreker, PR; Pal, MN, 1990) |
| "Trismus was significantly reduced in the He-Ne laser and ibuprofen treatment groups." | 2.67 | A randomized double-blind clinical trial on the effectiveness of helium-neon laser in the prevention of pain, swelling and trismus after removal of impacted third molars. ( Barberia, E; Calatayud, J; Carrillo, JS; Donado, M; Manso, FJ; Martinez, JM, 1990) |
| "Ibuprofen 400 mg was more effective than acetaminophen 1000 mg for the sum of pain intensity difference, total pain relief, and reduction of pain by more than 50% (P less than ." | 2.66 | Ibuprofen and acetaminophen in the relief of postpartum episiotomy pain. ( Baybutt, RI; Schachtel, BP; Thoden, WR, 1989) |
| "Ibuprofen 400 mg was more effective than acetaminophen 1000 mg for Sum Pain Intensity Difference (SPID), Total Pain Relief (TOTPAR), sum pain half-gone, and overall evaluation (P less than ." | 2.66 | Ibuprofen and acetaminophen in the relief of acute pain: a randomized, double-blind, placebo-controlled study. ( Cohn, P; Cooper, SA; Gelb, S; Goldman, E; Schachtel, BP, 1989) |
| "Ibuprofen is an appropriate analgesic for treating post-operative dental pain." | 2.66 | A comparison of ibuprofen and dihydrocodeine in relieving pain following wisdom teeth removal. ( Evans, CR; Flaum, GR; Frame, JW; Langford, R; Rout, PG, 1989) |
| "Codeine 60 mg was statistically superior to placebo based on TOTPAR, the global ratings, and a few hourly measures." | 2.66 | Analgesic efficacy of two ibuprofen-codeine combinations for the treatment of postepisiotomy and postoperative pain. ( Laska, EM; Olson, N; Rivera, J; Roure, C; Sunshine, A; Zorrilla, C, 1987) |
| "Ibuprofen, 400 mg, was compared with 300 mg acetaminophen plus 30 mg of codeine and placebo in 120 post-orthopedic surgery patients with moderate to severe pain." | 2.66 | Efficacy and quality of ibuprofen and acetaminophen plus codeine analgesia. ( Heidrich, G; Kaiko, RF; Slavic-Svircev, V, 1985) |
| "Ibuprofen pretreatment resulted in significantly less pain than placebo or acetaminophen pretreatment as the local anesthetic wore off." | 2.65 | Suppression of postoperative pain by preoperative administration of ibuprofen in comparison to placebo, acetaminophen, and acetaminophen plus codeine. ( Buckingham, B; Campbell, RA; Cooper, SA; Dionne, RA; Hall, DL, 1983) |
| "Ibuprofen, 400 mg, is an effective oral analgesic and is more effective than 100 mg zomepirac and 600 mg aspirin in most parameters of pain." | 2.65 | Ibuprofen, zomepirac, aspirin, and placebo in the relief of postepisiotomy pain. ( De Castro, A; De Sarrazin, C; Laska, EM; Olson, NZ; Sunshine, A; Zighelboim, I, 1983) |
| "Ibuprofen was significantly better than ACC-30 and placebo on almost all pain intensity, degree of relief and duration of analgesia parameters." | 2.65 | A double-blind comparison of ibuprofen, ASA-codeine-caffeine compound and placebo in the treatment of dental surgery pain. ( Masson, EL; Squires, DJ, 1981) |
| " Time-effect and dose-response curves were generated from the relief and change in pain-intensity scores." | 2.64 | Comparative analgesic potency of aspirin and ibuprofen. ( Cooper, SA; Kruger, GO; Needle, SE, 1977) |
| "of ibuprofen was compared to that of 650 mg." | 2.64 | Analgesic activity of ibuprofen (Motrin) in postoperative oral surgical pain. ( Bass, E; Cahaly, JF; Recant, B; Winter, L, 1978) |
| "The pharmacological agents approved for treating pain in these patients are few, also considering the recent limitation for codeine in children younger than 12 years." | 2.61 | Ibuprofen in the treatment of children's inflammatory pain: a clinical and pharmacological overview. ( Barbagallo, M; Sacerdote, P, 2019) |
| "Anxiety reduction may lead to less postoperative pain." | 2.61 | Postoperative Pain Management in Dermatologic Surgery: A Systematic Review. ( Golda, N; Saco, M, 2019) |
| "Ibuprofen was the most studied NSAID." | 2.55 | Nonsteroidal Anti-inflammatory Drugs for Managing Postoperative Endodontic Pain in Patients Who Present with Preoperative Pain: A Systematic Review and Meta-analysis. ( Barker, DR; Marshall, JG; Sedgley, CM; Selph, SS; Smith, EA, 2017) |
| "Ibuprofen is a useful medication in the setting of surgery, with multiple beneficial effects." | 2.53 | Ibuprofen May Not Increase Bleeding Risk in Plastic Surgery: A Systematic Review and Meta-Analysis. ( Bennett, KG; Chung, KC; Kelley, BP; Kozlow, JH, 2016) |
| "This appears to be broadly true in postoperative pain and migraine headache across a range of different drug combinations and when tested in the same and different trials." | 2.52 | Single dose oral ibuprofen plus codeine for acute postoperative pain in adults. ( Derry, S; Karlin, SM; Moore, RA, 2015) |
| "This appears to be broadly true in postoperative pain and migraine headache across a range of different drug combinations, and when tested in the same and different trials." | 2.52 | Single dose oral ibuprofen plus caffeine for acute postoperative pain in adults. ( Derry, S; Moore, RA; Wiffen, PJ, 2015) |
| "This appears to be broadly true in postoperative pain and migraine headache across a range of different drug combinations and when tested in the same and different trials." | 2.49 | Single dose oral ibuprofen plus codeine for acute postoperative pain in adults. ( Derry, S; Karlin, SM; Moore, RA, 2013) |
| "The information from the single trial in acute postoperative pain suggests it to be a useful analgesic, but at doses not very different from racemic ibuprofen." | 2.45 | Single dose oral dexibuprofen [S(+)-ibuprofen] for acute postoperative pain in adults. ( Derry, S; McQuay, HJ; Moore, RA, 2009) |
| "The postoperative pain is related with surgical procedure irrevocable." | 2.43 | [Postoperative pain therapy in otolaryngological department]. ( Kocot-Kepska, M; Muszyński, T; Nosek-Kozdra, K; Przeklasa-Muszyńska, A, 2006) |
| "Ibuprofen is an effective analgesic in post-operative pain." | 2.40 | Analgesic efficacy of ibuprofen alone and in combination with codeine or caffeine in post-surgical pain: a meta-analysis. ( Po, AL; Zhang, WY, 1998) |
| " Dose-response relationships show that higher doses of ibuprofen may be particularly effective." | 2.40 | Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review. ( McQuay, HJ; Moore, RA, 1998) |
| "Acute pain is a common symptom in children of all ages, and is associated with a variety of conditions." | 1.91 | Paracetamol and ibuprofen combination for the management of acute mild-to-moderate pain in children: expert consensus using the Nominal Group Technique (NGT). ( Chiarugi, A; Cortis, E; D'Avino, A; Lanari, M; Marchisio, PG; Parri, N; Silvagni, D; Staiano, A; Vezzoli, C; Zampogna, S, 2023) |
| "Postoperative pain is commonly severe for 1-2 weeks, but parental analgesia concerns lead to poor analgesia prescription compliance and under administration." | 1.91 | A service evaluation of the impact of parental information provision on analgesia administration at home posttonsillectomy. ( Bew, S; Bliss, A; Gupta, E; Nicholls, A, 2023) |
| "Acetaminophen is a popular, universally used, over-the-counter pain medication contained in more than 600 different products and available in a plethora of dosage forms." | 1.72 | Acetaminophen: Is Too Much of a Good Thing Too Much? ( Donaldson, M; Goodchild, JH, 2022) |
| "Ibuprofen appears to be a safe option for fracture-related pain." | 1.62 | An observational cohort study comparing ibuprofen and oxycodone in children with fractures. ( Ali, S; Carleton, B; Drendel, AL; Johnson, DW; LeMay, S; Manaloor, R; McGrath, PJ; Rosychuk, RJ, 2021) |
| " Opioid outcomes calculated in morphine milligram equivalents per kilogram (MME/kg) per dosage and total prescribed." | 1.62 | Pediatric Post-Tonsillectomy Opioid Prescribing Practices. ( Agamawi, YM; Brinkmeier, JV; Cass, LM; Mouzourakis, M; Pannu, JS, 2021) |
| "Ibuprofen 600 mg was very effective in controlling inflammatory pain after lower third molar surgeries, without relevant adverse reactions; although in a very subtle way, patients with poor metabolism had higher levels of pain in the first hours, and no longer after 8 h, and used pain relief medication earlier." | 1.62 | CYP450 polymorphisms and clinical pharmacogenetics of ibuprofen after lower third molar extraction. ( Absher, DM; Bonjardim, LR; Calvo, AM; Colombini-Ishiquiriama, BL; Costa, YM; Dionísio, TJ; Moore, T; Oliveira, GM; Santos, CF; Torres, EA; Weckwerth, GM, 2021) |
| "Parents completed the Parents' Postoperative Pain Measure (PPPM-D) in addition." | 1.62 | Pain in children undergoing tonsillotomy with alternating ibuprofen and paracetamol - a prospective observational study. ( Dazert, S; Geldermann, N; Georgevici, AI; Gude, P; Herzog-Niescery, J; van Ackeren, K; Vogelsang, H; Volkenstein, S; Weber, TP, 2021) |
| " Results The scheduled dosing group was found to have a statistically significant decrease in pain scores at all time intervals." | 1.56 | The effect of a scheduled regimen of acetaminophen and ibuprofen on opioid use following cesarean delivery. ( Chappelle, J; Poljak, D, 2020) |
| " We sought to evaluate the effectiveness and safety of over the counter dosing of ibuprofen on pain and bleeding rates following ESS." | 1.56 | Effect of Over the Counter Ibuprofen Dosing after Sinus Surgery for Chronic Rhinosinusitis: A Prospective Cohort Pilot Study. ( Davis, GE; Humphreys, IM; Miller, C, 2020) |
| "Ibuprofen use was associated with using fewer opioid tablets (p = ." | 1.56 | National opioid prescription patterns and patient usage after routine vasectomy. ( Asanad, K; Nusbaum, DJ; Samplaski, MK, 2020) |
| "Ibuprofen was orally administered every 8 h." | 1.56 | High dose ibuprofen as a monotherapy on an around-the-clock basis fails to control pain in children undergoing tonsil surgery: a prospective observational cohort study. ( Bellgardt, M; Dazert, S; Gude, P; Gustedt, F; Herzog-Niescery, J; Vogelsang, H; Volkenstein, S; Weber, TP, 2020) |
| "In this Quality Improvement (QI project) it was hypothesized that an increase in dosing intervals for postoperative analgesia when alternating Ibuprofen and Acetaminophen would reduce post-tonsillectomy hemorrhage (PTH) rates for those undergoing tonsillectomies with or without adenoidectomy, while maintaining the standard of postoperative analgesia and reducing visits to the Emergency Room (ER) for reasons other than PTH." | 1.56 | The Effect of Ibuprofen Dosing Interval on Post-Tonsillectomy Outcomes in Children: A Quality Improvement Study. ( Carr, MM; Henderson, K; Mast, G, 2020) |
| " The purpose of this study was to examine opioid use in the pediatric fracture population by determining and comparing the average hospital opioid dosage utilized in the operative pediatric elbow and femur fractures and determining and comparing the average dose prescribed following operative treatment of elbow and femur fractures." | 1.51 | Opioid Use Following Operatively Treated Pediatric Elbow and Femur Fractures. ( Krucylak, P; Meyer, ZI; Miller, ML; Mo, M; Wall, LB, 2019) |
| "Oral ibuprofen is believed to be safe and effective after pediatric adenotonsillectomy." | 1.48 | Safety of preoperative ibuprofen in pediatric tonsillectomy. ( Buchinsky, FJ; Isaacson, G; Michael, A, 2018) |
| "To reduce postoperative pain effectively and safely." | 1.48 | Analgesic Effect of Local Infiltration of the Surgical Wound Containing Levobupivacaine, Ibuprofen, and Epinephrine in Rats Undergoing Laparotomy. ( Kapupara, P; Korat, PS, 2018) |
| "The reduction in postoperative pain started within 1h after the suturing of the tissues in the treatment group." | 1.46 | Local infiltration of the surgical wounds with levobupivacaine, dexibuprofen, and norepinephrine to reduce postoperative pain: A randomized, vehicle-controlled, and preclinical study. ( Cao, X; Cui, F; Gao, Z; Li, T; Li, X; Wang, D, 2017) |
| "Postoperative pain was assessed by rodent grimace scales scoring." | 1.46 | Local infiltration of the surgical wound with levobupivacaine, ibuprofen, and epinephrine in postoperative pain: An experimental study. ( Kapupara, PP; Korat, PS, 2017) |
| "Control of postoperative pain is far from satisfactory." | 1.43 | Nitric oxide is involved in ibuprofen preemptive analgesic effect in the plantar incisional model of postsurgical pain in mice. ( Bahr, MH; Hamza, M; Masoud, SI; Saad, SS, 2016) |
| "Pain subsided over 3 days." | 1.42 | Postoperative Pain in Children After Dentistry Under General Anesthesia. ( Copp, PE; Haas, DA; Wong, M, 2015) |
| "Ibuprofen was found to be a superior analgesic to paracetamol at several doses, with high quality evidence suggesting that ibuprofen 400 mg is superior to 1000 mg paracetamol based on pain relief (estimated from TOTPAR data) and the use of rescue medication meta-analyses." | 1.40 | Ibuprofen is superior to paracetamol for pain relief following third molar removal. ( Ferraiolo, DM; Veitz-Keenan, A, 2014) |
| " We conclude that repeated dosing through transversus abdominis plane catheters may be offered to women as an alternative or adjuvant to intrathecal morphine." | 1.38 | Transversus abdominis plane catheters for post-cesarean delivery analgesia: a series of five cases. ( Bollag, L; Landau, R; Ortner, C; Richebe, P, 2012) |
| "To determine the risk of postoperative hemorrhage associated with the use of analgesic drugs including paracetamol, metamizole sodium and ibuprofen after pediatric tonsillectomy." | 1.38 | The effect of paracetamol, metamizole sodium and ibuprofen on postoperative hemorrhage following pediatric tonsillectomy. ( Kapusuz, Z; Özkiriş, M; Saydam, L; Yildirim, YS, 2012) |
| "Untreated postoperative pain is an important ethical and financial issue that can lead to unnecessary suffering and prolonged stays in hospital." | 1.37 | Reducing postoperative pain by changing the process. ( Armstrong, D; Boardman, C; Coulthard, P; Crawford, FI, 2011) |
| "In the treatment of uterine fibroid embolization related pain, the use of embolics loaded with non-steroidal anti-inflammatory drugs (NSAID) relies on an efficient delivery and impregnation of the embolized tissue." | 1.37 | IL6 and TNF expression in vessels and surrounding tissues after embolization with ibuprofen-loaded beads confirms diffusion of ibuprofen. ( Bédouet, L; Bevilacqua, C; Laurent, A; Lewis, AL; Martin, P; Namur, J; Pelage, JP; Schwartz-Cornil, I; Verret, V; Wassef, M, 2011) |
| "Nimesulide was the most prescribed NSAID (68%), followed by diclofenac, ketoprofen and ibuprofen." | 1.35 | Prescriptions of NSAIDs to patients undergoing third molar surgery : an observational, prospective, multicentre survey. ( Bandettini, M; Bertelli, E; Caputi, S; Carraro, M; Garau, V; Levrini, L; Lörincz, A; Pelliccioni, GA; Rizzo, S; Salgarello, S; Szûcs, A, 2008) |
| "Ibuprofen is a nonsteroidal anti-inflammatory drug which has both peripheral and central analgesic effects." | 1.33 | Perioperative pharmacokinetics of ibuprofen enantiomers after rectal administration. ( Kyllönen, M; Olkkola, KT; Ryhänen, P; Seppälä, T, 2005) |
| "Pretreatment with morphine 30 min before pulp exposure dose-dependently (2." | 1.33 | Effects of pre-emptive morphine, ibuprofen or local anesthetic on fos expression in the spinal trigeminal nucleus following tooth pulp exposure in the rat. ( Erickson, TE; Gebhart, GF; Johnson, WT; Law, AS; Locher-Claus, MT, 2005) |
| "Pain, swelling and trismus were the commonest complaints." | 1.31 | Postoperative complaints following impacted mandibular third molar surgery in Ile-Ife, Nigeria. ( Assam, E; Oginni, FO; Ogunbodede, EO; Ugboko, VI, 2002) |
| "We assessed the quality of assessment and reporting of adverse effects in randomized, double-blind clinical trials of single-dose acetaminophen or ibuprofen compared with placebo in moderate to severe postoperative pain." | 1.30 | Reporting of adverse effects in clinical trials should be improved: lessons from acute postoperative pain. ( Collins, SL; Edwards, JE; McQuay, HJ; Moore, RA, 1999) |
| "Ketoprofen is a nonsteroidal anti-inflammatory drug with both anti-inflammatory and analgesic properties." | 1.28 | The efficacy and safety of ketoprofen in postsurgical dental pain. ( Hersh, EV, 1991) |
| "Ibuprofen 400 mg was consistently more effective than aspirin 650 mg, acetaminophen 600 mg, and both aspirin and acetaminophen when combined with codeine 60 mg." | 1.27 | Five studies on ibuprofen for postsurgical dental pain. ( Cooper, SA, 1984) |
| "Ibuprofen was present in the serum with a half-life of approximately 1." | 1.27 | Excretion of ibuprofen into breast milk. ( Albert, KS; Benedetti, TJ; Cengiz, C; Erickson, SH; Gillespie, WR; Gschwend, J; Townsend, RJ, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 47 (8.39) | 18.7374 |
| 1990's | 77 (13.75) | 18.2507 |
| 2000's | 119 (21.25) | 29.6817 |
| 2010's | 198 (35.36) | 24.3611 |
| 2020's | 119 (21.25) | 2.80 |
| Authors | Studies |
|---|---|
| Dahm, V | 1 |
| Lui, JT | 1 |
| Chen, JM | 1 |
| Kiss, A | 1 |
| Hamour, AF | 1 |
| Le, TN | 1 |
| Lin, VY | 1 |
| Ferguson, MC | 1 |
| Schumann, R | 1 |
| Gallagher, S | 1 |
| McNicol, ED | 1 |
| Ali, S | 1 |
| Manaloor, R | 1 |
| Johnson, DW | 1 |
| Rosychuk, RJ | 1 |
| LeMay, S | 1 |
| Carleton, B | 1 |
| McGrath, PJ | 1 |
| Drendel, AL | 1 |
| Losorelli, SD | 1 |
| Scheffler, P | 1 |
| Qian, ZJ | 1 |
| Lin, HC | 1 |
| Truong, MT | 1 |
| Lyngstad, G | 2 |
| Skjelbred, P | 2 |
| Swanson, DM | 2 |
| Skoglund, LA | 4 |
| Lubis, AM | 1 |
| Maruanaya, S | 1 |
| Tantri, AR | 1 |
| Pontoh, LAP | 1 |
| Ifran, NNPPS | 1 |
| Watson, H | 1 |
| Hildebolt, C | 1 |
| Rowland, K | 1 |
| La Monaca, G | 2 |
| Pranno, N | 2 |
| Annibali, S | 2 |
| Polimeni, A | 2 |
| Pompa, G | 2 |
| Vozza, I | 1 |
| Cristalli, MP | 2 |
| Vallecillo, C | 1 |
| Vallecillo-Rivas, M | 1 |
| Gálvez, R | 1 |
| Vallecillo-Capilla, M | 1 |
| Olmedo-Gaya, MV | 1 |
| Gasbjerg, KS | 2 |
| Hägi-Pedersen, D | 9 |
| Lunn, TH | 3 |
| Laursen, CC | 1 |
| Holmqvist, M | 1 |
| Vinstrup, LØ | 1 |
| Ammitzboell, M | 1 |
| Jakobsen, K | 2 |
| Jensen, MS | 1 |
| Pallesen, MJ | 1 |
| Bagger, J | 1 |
| Lindholm, P | 4 |
| Pedersen, NA | 4 |
| Schrøder, HM | 4 |
| Lindberg-Larsen, M | 3 |
| Nørskov, AK | 2 |
| Thybo, KH | 9 |
| Brorson, S | 3 |
| Overgaard, S | 8 |
| Jakobsen, JC | 7 |
| Mathiesen, O | 12 |
| Lalonde, DH | 1 |
| Lalonde, JF | 1 |
| MacDermid, JC | 1 |
| Chung, KC | 2 |
| Gan, BS | 1 |
| Mierisch, C | 1 |
| Van Demark, RE | 1 |
| Luc, M | 1 |
| Tamimi, Z | 1 |
| Abusamak, M | 2 |
| Al-Waeli, H | 1 |
| Al-Tamimi, M | 1 |
| Al Habashneh, R | 1 |
| Ghanim, M | 1 |
| Al-Nusair, M | 1 |
| Gao, Q | 2 |
| Nicolau, B | 1 |
| Tamimi, F | 1 |
| Tomic, J | 1 |
| Wallner, J | 1 |
| Mischak, I | 1 |
| Sendlhofer, G | 1 |
| Zemann, W | 1 |
| Schanbacher, M | 1 |
| Hassanzadeh, H | 1 |
| Sandner-Kiesling, A | 1 |
| Payer, M | 1 |
| Zrnc, TA | 1 |
| DeVitis, J | 1 |
| Flom, E | 1 |
| Cooper-Roth, T | 1 |
| Davis, A | 1 |
| Krech, L | 1 |
| Fisk, C | 1 |
| Pounders, S | 1 |
| Kwazneski, D | 1 |
| Chapman, A | 1 |
| Valdez, C | 1 |
| Gettis, M | 1 |
| Brown, AM | 1 |
| Fujimoto, A | 1 |
| Wetzel, M | 1 |
| Thomsen, J | 1 |
| Ucar, M | 1 |
| Erdogan, MA | 1 |
| Sanlı, M | 2 |
| Colak, YZ | 1 |
| Aydogan, MS | 1 |
| Yucel, A | 1 |
| Ozgul, U | 2 |
| Schneider, T | 1 |
| Mauermann, E | 1 |
| Ilgenstein, B | 1 |
| Jaquiery, C | 1 |
| Ruppen, W | 1 |
| Lampert, A | 2 |
| Lange, R | 3 |
| Weiser, T | 3 |
| Goodchild, JH | 1 |
| Donaldson, M | 1 |
| Dahl, ME | 1 |
| McDonald, KC | 1 |
| Brown, O | 1 |
| Halder, G | 1 |
| Crouss, T | 1 |
| Pan, C | 1 |
| Eckhardt, S | 1 |
| Hoover, M | 1 |
| Dancz, CE | 1 |
| Teja, KV | 1 |
| Ramesh, S | 1 |
| Vasundhara, KA | 1 |
| Sherrer, R | 1 |
| Su, R | 1 |
| O'Kelly, F | 1 |
| Borza, T | 1 |
| Byrne, A | 1 |
| Finup, J | 1 |
| Farhat, W | 1 |
| Bamberger, JN | 1 |
| Gallante, B | 1 |
| Khusid, JA | 1 |
| Yaghoubian, A | 1 |
| Sadiq, A | 1 |
| Shimonov, R | 1 |
| Zampini, AM | 1 |
| Chandhoke, RA | 1 |
| Atallah, W | 1 |
| Gupta, M | 1 |
| Pérez-González, F | 1 |
| Sáez-Alcaide, LM | 1 |
| García-Denche, JT | 1 |
| Marino, FAT | 1 |
| Uysal, İ | 1 |
| Eratilla, V | 1 |
| Topbaş, C | 1 |
| Ergül, İ | 1 |
| Çelik, Y | 1 |
| Indermuhle, P | 1 |
| Zelko, M | 1 |
| Mori, C | 1 |
| Chiu, SH | 1 |
| Abdelbaser, I | 3 |
| Mageed, NA | 1 |
| El-Emam, EM | 1 |
| ALseoudy, MM | 1 |
| Sahin, GK | 1 |
| Gulen, M | 1 |
| Acehan, S | 1 |
| Satar, DA | 1 |
| Erfen, T | 1 |
| Satar, S | 1 |
| Steiness, J | 2 |
| Graungaard, BK | 2 |
| Lundstrom, LH | 1 |
| Bieder, MJ | 2 |
| Beck, T | 2 |
| Skettrup, M | 2 |
| von Cappeln, AG | 2 |
| Feng, H | 1 |
| König, J | 1 |
| König, T | 1 |
| Muensterer, O | 1 |
| Martin, LF | 1 |
| Cheng, K | 1 |
| Washington, SM | 1 |
| Denton, M | 1 |
| Goel, V | 1 |
| Khandekar, M | 1 |
| Largent-Milnes, TM | 1 |
| Patwardhan, A | 1 |
| Ibrahim, MM | 1 |
| Bjørnholdt, KT | 2 |
| Brix, LD | 1 |
| Xuan, C | 3 |
| Yan, W | 3 |
| Wang, D | 4 |
| Li, C | 3 |
| Ma, H | 3 |
| Mueller, A | 3 |
| Chin, V | 3 |
| Houle, TT | 3 |
| Wang, J | 3 |
| Abo-Zeid, M | 2 |
| Hayes, S | 2 |
| Taman, HI | 2 |
| Coll, Y | 2 |
| Geddes, A | 2 |
| Lundstrøm, LH | 1 |
| Varnum, C | 1 |
| Pleckaitiene, L | 1 |
| Anker Pedersen, N | 1 |
| De Ravin, E | 1 |
| Banik, GL | 1 |
| Buzi, A | 1 |
| Hashem, AAR | 1 |
| Abd El Sattar, AA | 1 |
| Abdel Rahman, TY | 1 |
| Miroshnychenko, A | 1 |
| Ibrahim, S | 1 |
| Azab, M | 1 |
| Roldan, Y | 1 |
| Martinez, JPD | 1 |
| Tamilselvan, D | 1 |
| He, L | 2 |
| Little, JW | 1 |
| Urquhart, O | 1 |
| Tampi, M | 1 |
| Polk, DE | 1 |
| Moore, PA | 4 |
| Hersh, EV | 8 |
| Claytor, B | 1 |
| Carrasco-Labra, A | 1 |
| Brignardello-Petersen, R | 4 |
| Stessel, B | 2 |
| Lambrechts, M | 1 |
| Evers, S | 2 |
| Vanderstappen, C | 1 |
| Callebaut, I | 1 |
| Ory, JP | 2 |
| Herbots, J | 1 |
| Dreesen, I | 1 |
| Vaninbroukx, M | 1 |
| Van de Velde, M | 2 |
| Creighton, EW | 1 |
| Dayer, L | 1 |
| King, D | 1 |
| Vural, E | 1 |
| Sunde, J | 1 |
| Moreno, MA | 1 |
| Stack, BC | 1 |
| Zhou, HS | 1 |
| Li, TT | 1 |
| Pi, Y | 1 |
| Wang, TH | 1 |
| Liu, F | 1 |
| Xiong, LL | 1 |
| Parri, N | 1 |
| Silvagni, D | 1 |
| Chiarugi, A | 1 |
| Cortis, E | 1 |
| D'Avino, A | 1 |
| Lanari, M | 1 |
| Marchisio, PG | 1 |
| Vezzoli, C | 1 |
| Zampogna, S | 1 |
| Staiano, A | 1 |
| Vatankhah, M | 1 |
| Zargar, N | 2 |
| Naseri, M | 1 |
| Salem, S | 1 |
| Baghban, AA | 1 |
| Etemadi, A | 1 |
| Dianat, O | 1 |
| Sundaramurthy, JL | 1 |
| Natanasabapathy, V | 1 |
| Mahendran, K | 1 |
| Narasimhan, S | 1 |
| Raghu, S | 1 |
| Cherian, AR | 1 |
| Vaanjay, M | 1 |
| Krithikadatta, J | 1 |
| Fowler, C | 1 |
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| Guo, N | 1 |
| Ansari, JR | 1 |
| Shafer, SL | 1 |
| Flood, PD | 1 |
| Kligerman, MP | 1 |
| Austerlitz, J | 1 |
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| Noel, JE | 1 |
| Glover, CD | 2 |
| Berkenbosch, JW | 1 |
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| Patel, NV | 1 |
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| Walls, HR | 1 |
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| Kain, ZN | 1 |
| Schlechter, JA | 1 |
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| Bliss, A | 1 |
| Zhou, P | 1 |
| Chen, L | 2 |
| Wang, E | 1 |
| Tian, S | 1 |
| Zhai, S | 1 |
| Hwang, JK | 1 |
| Ricardo, JW | 1 |
| Lipner, SR | 1 |
| Mattos-Pereira, GH | 1 |
| Esteves-Lima, RP | 1 |
| Cota, LOM | 3 |
| Alvarenga-Brant, R | 1 |
| Costa, FO | 3 |
| Daniels, SE | 6 |
| Playne, R | 2 |
| Stanescu, I | 4 |
| Zhang, J | 1 |
| Gottlieb, IJ | 2 |
| Atkinson, HC | 4 |
| Wetterslev, J | 6 |
| Dahl, JB | 8 |
| Bülow, HH | 3 |
| Ibsen, L | 1 |
| Troendle, DM | 1 |
| Gurram, B | 1 |
| Huang, R | 1 |
| Barth, BA | 1 |
| Derefinko, KJ | 1 |
| Salgado García, FI | 1 |
| Johnson, KC | 1 |
| Hand, S | 1 |
| Murphy, JG | 1 |
| McDevitt-Murphy, M | 1 |
| Suda, KJ | 1 |
| Andrasik, F | 1 |
| Bursac, Z | 1 |
| Chiu, CY | 1 |
| Talley, K | 1 |
| Brooks, JH | 1 |
| Atalay, YO | 2 |
| Mursel, E | 1 |
| Ciftci, B | 4 |
| Iptec, G | 1 |
| Nunes, EC | 1 |
| Herkrath, FJ | 1 |
| Suzuki, EH | 1 |
| Gualberto Júnior, EC | 1 |
| Marques, AAF | 1 |
| Sponchiado Júnior, EC | 1 |
| Ekinci, M | 3 |
| Stamos, A | 1 |
| Drum, M | 4 |
| Reader, A | 9 |
| Nusstein, J | 4 |
| Fowler, S | 3 |
| Beck, M | 8 |
| Weisz, RD | 1 |
| Fokin, AA | 1 |
| Lerner, V | 1 |
| Flynt, A | 1 |
| Macias-Perez, I | 1 |
| Pavliv, L | 3 |
| Crawford, M | 1 |
| Puente, I | 1 |
| Poljak, D | 1 |
| Chappelle, J | 1 |
| Musselman, E | 1 |
| Stannard, D | 1 |
| Miller, C | 1 |
| Humphreys, IM | 1 |
| Davis, GE | 1 |
| Patel, NK | 1 |
| Shah, SJ | 1 |
| Lee, NK | 1 |
| Carullo, VP | 1 |
| Yang, CJ | 1 |
| Papoian, V | 1 |
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| Villano, AM | 1 |
| Tolentino, RA | 1 |
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| Nosanov, LS | 1 |
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| Lee, HM | 2 |
| Park, JH | 3 |
| Park, SJ | 1 |
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| Canpolat, DG | 2 |
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| Demirbaş, AE | 2 |
| Weckwerth, GM | 1 |
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| Lee, AD | 1 |
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| Abushanab, D | 1 |
| Al-Badriyeh, D | 1 |
| Miller, AL | 1 |
| McCarty, JC | 1 |
| Bergmark, RW | 1 |
| Gadkaree, SK | 1 |
| Cohen, MS | 2 |
| Diercks, GR | 2 |
| Keamy, DJ | 1 |
| Mankarious, LA | 1 |
| Hartnick, CJ | 1 |
| Kp, K | 1 |
| R, B | 1 |
| Bongiovanni, T | 1 |
| Lancaster, E | 1 |
| Ledesma, Y | 1 |
| Whitaker, E | 1 |
| Steinman, MA | 1 |
| Allen, IE | 1 |
| Auerbach, A | 1 |
| Wick, E | 1 |
| Kim, SY | 1 |
| Lee, S | 1 |
| Lee, Y | 1 |
| Kim, H | 2 |
| Kim, KM | 1 |
| Saiz-Rodríguez, M | 1 |
| Valdez-Acosta, S | 1 |
| Borobia, AM | 1 |
| Burgueño, M | 1 |
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| Puerro, M | 1 |
| Llanos, L | 1 |
| Martínez-Pérez, D | 1 |
| Ochoa, D | 1 |
| Carcas, AJ | 1 |
| Abad-Santos, F | 1 |
| Bilgin, E | 1 |
| Ökten, Aİ | 1 |
| Akbas, S | 1 |
| Ozkan, AS | 1 |
| Durak, MA | 1 |
| Yologlu, S | 2 |
| Santos, BFE | 2 |
| Pinto Júnior, AAC | 1 |
| Araújo, AVA | 1 |
| Cyrino, RM | 2 |
| Vieth, MP | 1 |
| Deas, DE | 1 |
| Archontia Palaiologou, A | 1 |
| Diogenes, A | 1 |
| Mader, MJ | 1 |
| Mealey, BL | 1 |
| Vasconcelos, AMA | 1 |
| Cooney, MF | 1 |
| Elmowitz, JS | 1 |
| Shupak, RP | 1 |
| Raslan, N | 1 |
| Zouzou, T | 1 |
| Yang, H | 1 |
| Lee, HH | 1 |
| Martin-Tuite, P | 1 |
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| Stoller, M | 1 |
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| Isiordia-Espinoza, MA | 1 |
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| de Azevedo, CB | 1 |
| Valera, FCP | 1 |
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| Caetano, JVB | 1 |
| Queiroz, DLC | 1 |
| Anselmo-Lima, WT | 1 |
| Tamashiro, E | 1 |
| Mokhtari, NB | 1 |
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| Huang, JC | 1 |
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| Stokken, JK | 1 |
| O'Brien, EK | 1 |
| Shah, S | 2 |
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| Roozdar, P | 1 |
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| Hwang, PH | 1 |
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| Wickham, CJ | 1 |
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| Covani, U | 1 |
| Gabriele, M | 1 |
| Gao, Z | 1 |
| Cui, F | 1 |
| Cao, X | 1 |
| Li, X | 2 |
| Li, T | 1 |
| Best, AD | 1 |
| De Silva, RK | 1 |
| Thomson, WM | 1 |
| Tong, DC | 1 |
| Cameron, CM | 1 |
| De Silva, HL | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Maxigesic IV Bunionectomy Study- A Phase 3, Randomized, Double-Blind, Multiple-Dose, Parallel-Group and Placebo-Controlled Study[NCT02689063] | Phase 3 | 276 participants (Actual) | Interventional | 2016-10-26 | Completed | ||
| Analgesic Effect of Ibuprofen 400, 600 and 800 mg, Paracetamol 500 and 1000 mg, and Paracetamol 1000 mg Plus 60 mg Codeine: Single-dose, Randomized, Placebo-controlled and Double-blind Study on Acute Pain After Third Molar Surgery[NCT00699114] | Phase 4 | 350 participants (Anticipated) | Interventional | 2007-06-30 | Completed | ||
| Comparative Analgesic Effects of Preoperative Administration of Paracetamol (Acetominophen) 500 mg Plus Codeine 30 mg and Ibuprofen 400 mg on Pain After Third Molar Surgery[NCT04730297] | Phase 4 | 120 participants (Actual) | Interventional | 2018-01-01 | Completed | ||
| The Effects of Tramadol Combined With Local Anesthesia on Pain After the Surgical Extraction of Third Molars[NCT05614440] | Early Phase 1 | 60 participants (Actual) | Interventional | 2012-05-01 | Completed | ||
| Dexamethasone Twice for Pain Treatment of Total Knee Arthroplasty - A Randomized Blinded Placebo-controlled Clinical Trial[NCT03506789] | Phase 4 | 485 participants (Actual) | Interventional | 2018-09-14 | Completed | ||
| A Randomized, Controlled Trial Comparing Combination Therapy of Ibuprofen + Acetaminophen Versus Hydrocodone + Acetaminophen for the Treatment of Pain After Carpal Tunnel Surgery[NCT01974609] | Phase 4 | 347 participants (Actual) | Interventional | 2016-03-31 | Completed | ||
| Gabapentin Premedication for Pediatric Anterior Cruciate Ligament Reconstruction: Randomized Control Trial[NCT03417479] | 57 participants (Actual) | Observational | 2015-10-09 | Completed | |||
| Effect of Combinations of Paracetamol, Ibuprofen, and Dexamethasone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty. The RECIPE Randomized Clinical Trial[NCT04123873] | Phase 4 | 1,060 participants (Actual) | Interventional | 2020-03-05 | Completed | ||
| IV Ibuprofen for the Prevention of Post-ERCP Pancreatitis[NCT02241512] | Phase 2 | 69 participants (Actual) | Interventional | 2014-09-30 | Terminated (stopped due to lack of funding) | ||
| Comparison of Ultrasound-guided Clavipectoral Fascia Plane Block and Interscalen Brachial Plexus Block for Analgesia After Clavicle Surgery[NCT04332497] | 0 participants (Actual) | Interventional | 2020-04-10 | Withdrawn (stopped due to no participants) | |||
| The Effectiveness of Clavipectoral Fascia Plane Block for Analgesia After Clavicle Surgery: Randomized, Prospective Study[NCT04328558] | 0 participants (Actual) | Interventional | 2020-04-22 | Withdrawn (stopped due to no participants) | |||
| The Effect of Clavipectoral Fascia Plane Block on Pain Management and Patient Satisfaction Following Clavicle Surgery: Randomized, Prospective Study[NCT05268874] | 38 participants (Actual) | Interventional | 2022-03-18 | Completed | |||
| Assessing the Efficacy of IV Ibuprofen for Treatment of Pain in Orthopedic Trauma Patients[NCT02152163] | Phase 4 | 99 participants (Actual) | Interventional | 2012-10-31 | Completed | ||
| Post-operative Pain Control With Acetaminophen and Ibuprofen After Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: a Prospective Study.[NCT05287217] | 60 participants (Anticipated) | Interventional | 2022-07-29 | Not yet recruiting | |||
| Assessing Perceived Quality of Care With Differing Pain Management Protocols After Outpatient Otolaryngology Procedures[NCT04976387] | Phase 3 | 150 participants (Actual) | Interventional | 2021-07-02 | Completed | ||
| A Single-centre, Double-blind, Randomised, Two-stage, Parallel-group Study to Assess the Efficacy and Safety of the Fixed Dose Combination of Ibuprofen 400 mg and Caffeine 100 mg Versus Ibuprofen 400 mg, Caffeine 100 mg and Placebo in Patients With Postop[NCT01929031] | Phase 3 | 562 participants (Actual) | Interventional | 2013-08-31 | Completed | ||
| EVALUATION OF THE EFFICACY OF NOVEL IBUPROFEN ACETAMINOPHEN COMBINATION FORMULATIONS IN THE TREATMENT OF POST-SURGICAL DENTAL PAIN[NCT01559259] | Phase 2 | 394 participants (Actual) | Interventional | 2012-04-10 | Completed | ||
| Comparison of the Effect of Propacetamol, Ibuprofen or Their Combination on Postoperative Pain and Quality of Recovery After Laparoscopic Hernia Repair in Children[NCT03352362] | 159 participants (Actual) | Interventional | 2017-12-15 | Completed | |||
| Clinical Pharmacogenetic of Ibuprofen Enantiomers After Lower Third Molar Surgeries[NCT03169127] | Phase 4 | 200 participants (Actual) | Interventional | 2016-04-01 | Active, not recruiting | ||
| Comparing Protocols for Analgesia Following Elective Cesarean Section[NCT03622489] | Phase 4 | 120 participants (Anticipated) | Interventional | 2017-03-01 | Recruiting | ||
| Effect of Submucosal Dexamethasone on Postoperative Pain, Swelling and Trismus After Periodontal Surgery: Randomized Clinical Study[NCT06119893] | 25 participants (Actual) | Interventional | 2021-08-12 | Completed | |||
| Educational Video on Pain Management and Subsequent Opioid Use After Cesarean Delivery[NCT03959969] | 48 participants (Actual) | Interventional | 2019-07-17 | Completed | |||
| Multi-institutional, Randomized Controlled Trial Assessing Opioid Use and Analgesic Requirements After Endoscopic Sinus Surgery[NCT03783702] | Phase 4 | 118 participants (Actual) | Interventional | 2019-04-04 | Completed | ||
| Opioid-Free Versus Transitional Anesthetic With Opioids From Tonsillectomy[NCT04528173] | Phase 4 | 550 participants (Anticipated) | Interventional | 2020-07-22 | Recruiting | ||
| The Effect of a Non-Opioid Multimodal Pain (NOMO) Protocol in Decreasing Narcotic Use After Urogynecologic Surgery[NCT05386069] | Phase 3 | 11 participants (Actual) | Interventional | 2019-11-15 | Completed | ||
| Nurses' Knowledge and Attitudes Towards Opioids in Pain Management in North Cyprus[NCT04252443] | 127 participants (Actual) | Interventional | 2018-06-01 | Completed | |||
| Efficacy of the Dosage of a Non-steroidal Anti-inflammatory (Ibuprofen) on Inflammation and Postoperative Pain After Lower Third Molar Surgery.[NCT05126264] | 10 participants (Actual) | Interventional | 2021-12-10 | Completed | |||
| PAracetamol and NSAID in Combination: A Randomised, Blinded, Parallel, 4-group Clinical Trial[NCT02571361] | Phase 4 | 556 participants (Actual) | Interventional | 2015-11-30 | Completed | ||
| Relieving Acute Pain (RAP): A Pilot Study[NCT03426137] | Phase 2 | 3 participants (Actual) | Interventional | 2018-09-17 | Terminated (stopped due to The focus of the project has shifted to publishing a protocol for future trials because we were unable to recruit. Three participants signed the consent forms but withdrew before the randomization.) | ||
| Efficiency And Quality In Post-Surgical Pain Therapy After Discharge[NCT05221866] | 711 participants (Actual) | Interventional | 2022-03-14 | Completed | |||
| Using Difference-in-Differences to Evaluate the Effect of a Statewide Quality Improvement Program on New Persistent Opioid Use After Surgery[NCT04805229] | 30,000 participants (Actual) | Observational | 2013-01-01 | Completed | |||
| A Randomized, Double-Blind, Double-Dummy, Placebo-Controlled, Adaptive Design, Single-Dose Study of Intravenous N1539 in the Treatment of Pain Secondary to Dental Impaction Surgery[NCT00945763] | Phase 2 | 230 participants (Actual) | Interventional | 2009-07-31 | Completed | ||
| Randomized, Controlled Trial of Post-operative Steroids and Pain Control After Tonsillectomy[NCT03995628] | Phase 2 | 150 participants (Anticipated) | Interventional | 2018-12-18 | Recruiting | ||
| Post-operative Course of Dexamethasone to Reduce Tonsillectomy Morbidity[NCT04879823] | Phase 3 | 300 participants (Anticipated) | Interventional | 2021-08-05 | Recruiting | ||
| A Single Institutional Randomized Controlled Trial for A Multimodal Enhanced Recovery Program in Anorectal Surgery[NCT03992079] | 60 participants (Actual) | Interventional | 2019-06-20 | Terminated (stopped due to PI is no longer at institution) | |||
| Optimization of Opioid Discharge Prescriptions Following Thyroid and Parathyroid Surgeries[NCT04955444] | 240 participants (Actual) | Interventional | 2021-06-14 | Completed | |||
| Impact of Counseling and Education on Opioid Consumption After Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial[NCT04885231] | 80 participants (Anticipated) | Interventional | 2021-05-12 | Active, not recruiting | |||
| Maxigesic 325 Acute Dental Pain Study: A Double-blind, Placebo-controlled, Randomized, Parallel Group Comparison of the Effects of Maxigesic 325 Versus Acetaminophen, Ibuprofen and Placebo in Participants With Acute Dental Pain[NCT01420653] | Phase 3 | 408 participants (Actual) | Interventional | 2013-04-30 | Completed | ||
| Preoperative Melatonin to Decrease Analgesia Usage After Third Molar Surgery[NCT04791943] | Phase 2 | 60 participants (Anticipated) | Interventional | 2021-05-12 | Recruiting | ||
| Comparison of Lidocaine, Dexmedetomidine and Ketamine in Multimodal Analgesia Management Following Sleeve Gastrectomy Surgery: A Randomized Double-Blind Trial[NCT04836819] | 78 participants (Actual) | Interventional | 2021-04-08 | Completed | |||
| Comparison of Intravenous Ibuprofen and Erector Spinae Plane Block for Postoperative Pain Management After Laparoscopic Sleeve Gastrectomy. A Randomized Controlled Study[NCT04232072] | 0 participants (Actual) | Interventional | 2020-02-11 | Withdrawn (stopped due to no participants) | |||
| Pain Reduction and Changes in Upper Limb Function Produced by Physiotherapy, Ibuprofen Arginine, Gabapentin and the Absence of Treatment, in Carpal Tunnel Syndrome[NCT04025203] | Phase 4 | 80 participants (Anticipated) | Interventional | 2019-08-01 | Recruiting | ||
| Pain Reduction and Changes in Upper Limb Function Produced by Over the Counter Oral Ibuprofen Versus the Lack of Treatment, in Carpal Tunnel Syndrome.[NCT04328805] | Phase 4 | 45 participants (Anticipated) | Interventional | 2020-09-30 | Not yet recruiting | ||
| Pain Reduction Produced by Physiotherapy, Ibuprofen, and the Absence of Treatment, in Carpal Tunnel Syndrome[NCT04119739] | Phase 4 | 74 participants (Anticipated) | Interventional | 2020-04-14 | Not yet recruiting | ||
| The Effect of Electroacupuncture (EA) on the Success of Inferior Alveolar Nerve Block (IANB) and Post-operative Pain Relief in Mandibular Molar With Symptomatic Irreversible Pulpitis (SIP) Among Malaysians: A Study Protocol for Randomized Double-Blinded C[NCT04804761] | 20 participants (Anticipated) | Interventional | 2023-01-01 | Recruiting | |||
| Prospective, Randomized, Controlled Trial of an Opiate Sparing Protocol Versus Standard Opiate Based Protocol Following Open Reduction Internal Fixation of Distal Radius Fractures[NCT05215236] | 72 participants (Anticipated) | Interventional | 2022-03-01 | Enrolling by invitation | |||
| Achieving Peri-Operative Pain Control Without Opioids[NCT04813991] | Phase 3 | 0 participants (Actual) | Interventional | 2022-03-15 | Withdrawn (stopped due to Enrollment was never initiated and the PI is leaving the institution so the study is closing.) | ||
| Oxycodone or Ibuprofen for Suspected Isolated Forearm Fractures in Pediatric Patients: A Randomized Noninferiority Trial[NCT04523623] | 200 participants (Anticipated) | Interventional | 2020-09-30 | Not yet recruiting | |||
| Postoperative Ibuprofen and the Risk of Bleeding After Tonsillectomy With or Without Adenoidectomy[NCT01605903] | Phase 2 | 741 participants (Actual) | Interventional | 2012-05-03 | Completed | ||
| The Effectiveness Of Intravenous Ibuprofen Versus Intravenous Ketorolac For Postoperative Pain Relief After Cesarean Section[NCT05907993] | Phase 4 | 50 participants (Actual) | Interventional | 2023-02-01 | Active, not recruiting | ||
| Randomized Trial of Bupivacaine as Adjuvant for Post-operative Pain in Mohs Micrographic Surgery[NCT04362566] | Phase 4 | 174 participants (Actual) | Interventional | 2020-07-30 | Completed | ||
| Postoperative Analgesic Efficacy of Ultrasound-guided Para-sartorial Compartment Block in Knee Surgery: A Randomized Study[NCT05566561] | 60 participants (Anticipated) | Interventional | 2022-10-19 | Recruiting | |||
| Postoperative Analgesic Efficacy of Local Infiltration Analgesia Versus Adductor Canal Block After Anterior Cruciate Ligament Reconstruction: A Randomised Controlled Double-blinded Trial[NCT02524652] | Phase 4 | 104 participants (Actual) | Interventional | 2015-09-30 | Completed | ||
| Analgesic Efficacy of IPACK Versus Selective Tibial Nerve Block in Patients Scheduled for Anterior Cruciate Ligament Reconstruction Under General Anaesthesia With an Adductor Canal Block: a Randomized Controlled Double-blinded Trial[NCT05303233] | 80 participants (Anticipated) | Interventional | 2022-05-01 | Recruiting | |||
| A Prospective Pilot Study of a Non-Narcotic Post-Operative Course After Colectomy[NCT05200806] | Phase 4 | 25 participants (Anticipated) | Interventional | 2022-02-07 | Recruiting | ||
| STandard Versus No Opioid Prescription After Prolapse and Anti-INcontinence Surgery: A Randomized Controlled, Non-inferiority Trial[NCT04491617] | 148 participants (Actual) | Interventional | 2020-08-27 | Completed | |||
| UControlPain App (This is the Official IRB Title)[NCT03833648] | 60 participants (Actual) | Interventional | 2019-06-19 | Completed | |||
| Effect of Paracetamol and Ibuprofen When Intravenously Given Combination or Alone in Reducing Morphine Requirements After Total Knee Arthroplasty[NCT04414995] | Phase 2/Phase 3 | 36 participants (Actual) | Interventional | 2020-06-05 | Completed | ||
| Comparison of the Effect of Intra-articular Administration of 2% Ropivacaine vs. 7.5% Ropivacaine as an Analgesic in the Immediate Postoperative Period of Knee Arthroscopy in Acute Injuries at the ABC Medical Center[NCT05807945] | Phase 4 | 68 participants (Actual) | Interventional | 2020-04-01 | Completed | ||
| Demonstration of OTC Naproxen Sodium's (Aleve's) Anti-inflammatory Action in Dental Implant Surgery Patients[NCT04694300] | Phase 4 | 32 participants (Actual) | Interventional | 2021-02-07 | Completed | ||
| [NCT02291705] | Phase 4 | 40 participants (Actual) | Interventional | 2012-01-31 | Completed | ||
| A Phase III Randomized, Double-Blind, Placebo- and Active-Comparator-Controlled, Multiple-Dose, Clinical Trial to Study the Safety and Efficacy of MK0663/Etoricoxib and Ibuprofen in the Treatment of Postorthopedic Knee Replacement Surgery Pain[NCT00820027] | Phase 3 | 776 participants (Actual) | Interventional | 2008-12-15 | Completed | ||
| Efficacy of Adding Dexmedetomidine Versus Ibuprofen as an Adjuvant to Intraperitoneal Bupivacaine for Pain Control After Laparoscopic Gynecological Procedures: a Double-blind Randomized Comparative Study[NCT06046105] | Phase 2/Phase 3 | 180 participants (Anticipated) | Interventional | 2023-09-15 | Not yet recruiting | ||
| Multimodal Opiate-sparing Analgesia Versus Traditional Opiate Based Analgesia After Cardiac Surgery, a Randomized Controlled Trial[NCT01966172] | Phase 4 | 180 participants (Actual) | Interventional | 2007-03-31 | Completed | ||
| Analysis of the Complications in Palatal Graft Harvesting With the UPV/EHU Technique vs. Single Incision Technique.[NCT06114394] | 70 participants (Anticipated) | Interventional | 2023-10-30 | Not yet recruiting | |||
| A Multicenter Randomized Controlled Study Comparing Connective Tissue Graft With Collagen Matrix to Re-establish Convexity at the Buccal Aspect of Single Dental Implants[NCT04210596] | 60 participants (Actual) | Interventional | 2019-09-01 | Active, not recruiting | |||
| High Dose Dexamethasone as Pain Treatment After Arthroscopic Shoulder Surgery: A Randomised, Blinded Clinical Trial[NCT01414569] | Phase 4 | 97 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| Efficacy of Intra-operative Subacromial Corticosteroid Injections on Surgical Outcomes After Arthroscopic Shoulder Surgery[NCT02867904] | Phase 4 | 12 participants (Actual) | Interventional | 2016-03-31 | Terminated (stopped due to It was difficult to recruit patients to get the appropriate sample size.) | ||
| Evaluation Of The Efficacy Of A Novel Ibuprofen Formulation In The Treatment Of Post-Surgical Dental Pain: Study I[NCT01098747] | Phase 3 | 335 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| Effect of Gabapentin on Postoperative Opioid Analgesic Use and Pain in Adolescents Undergoing Tonsillectomy[NCT05024825] | Phase 4 | 17 participants (Actual) | Interventional | 2017-08-04 | Terminated (stopped due to recruitment target not met.) | ||
| A Multi-Center, Open-Label, Surgical Surveillance Trial To Evaluate The Safety And Efficacy Of A Shortened Infusion Time of Intravenous Ibuprofen[NCT01334957] | Phase 4 | 300 participants (Actual) | Interventional | 2011-06-30 | Completed | ||
| Comparison of the Postoperative Analgesia Effectiveness of Preemptive Intravenous Ibuprofen and Paracetamol in Patients Undergoing Laparoscopic Cholecystectomy[NCT03063658] | Phase 4 | 108 participants (Anticipated) | Interventional | 2017-02-01 | Recruiting | ||
| A Prospective Randomized Double-blind Placebo Controlled Trial; Does Pre and Postoperative Dextromethorphan Reduce Post-tonsillectomy Pain in Children?[NCT02727491] | Phase 4 | 85 participants (Actual) | Interventional | 2012-03-31 | Completed | ||
| Investigating the Safety of Morphine and Ibuprofen in Children Post-adenotonsillectomy for Obstructive Sleep Apnea[NCT01680939] | Phase 3 | 120 participants (Anticipated) | Interventional | 2012-05-31 | Recruiting | ||
| Randomized Clinical Trial of Non-Opioid Pain Medications After Adenotonsillectomy[NCT03618823] | Phase 1/Phase 2 | 268 participants (Actual) | Interventional | 2018-10-25 | Terminated (stopped due to Early termination due to COVID-19 cases and cancelled surgeries.) | ||
| Postoperative Ibuprofen Use and Risk of Bleeding in Pediatric Tonsillectomy[NCT03385057] | Phase 1 | 0 participants (Actual) | Interventional | 2018-09-30 | Withdrawn (stopped due to Study design flaws; research design needed to be reconfigured) | ||
| Clonidine for Tourniquet-related Pain in Children: A Pilot Study[NCT04564430] | Phase 4 | 20 participants (Anticipated) | Interventional | 2021-03-01 | Recruiting | ||
| Use of a Non-Opioid Pain Regimen for Post-Operative Analgesia Following Intracapsular Adenotonsillectomy[NCT04791761] | Phase 1/Phase 2 | 300 participants (Anticipated) | Interventional | 2021-04-13 | Recruiting | ||
| Effectiveness of a Combined Acetaminophen and Ibuprofen Regimen for Management of Post-Tonsillectomy Pain in Pediatric Patients[NCT04551196] | Phase 3 | 47 participants (Actual) | Interventional | 2020-09-28 | Completed | ||
| The Effect of Dexamethasone in Combination With Paracetamol and Ibuprofen as Adjuvant, Postoperative Pain After Herniated Disc Surgery[NCT01953978] | Phase 4 | 160 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| Assessment of Postoperative Pain After Using Reciroc Versus One Shape NiTi Systems in Patients With Symptomatic Irreversible Pulpitis (A Randomized Clinical Trial): Part Two[NCT02940782] | 54 participants (Anticipated) | Interventional | 2017-01-31 | Not yet recruiting | |||
| Assessment of Postoperative Pain After Using Reciproc Versus One Shape NiTi Systems in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial (Part I)[NCT02940704] | 54 participants (Actual) | Interventional | 2016-11-30 | Completed | |||
| Postoperative Pain Incidence of Asymptomatic Mandibular Molar Teeth After Using Different Engine-driven Systems[NCT04454814] | 120 participants (Actual) | Interventional | 2017-10-15 | Completed | |||
| Assessment of Postoperative Pain After Using Two Formulations of Calcium Hydroxide Intracanal Medication : A Randomized Clinical Trial.[NCT05021809] | Phase 4 | 60 participants (Anticipated) | Interventional | 2021-07-25 | Recruiting | ||
| Efficacy of Pain Control Following Root Canal Treatment Using Paracetamol Alone and in Combination With Three Different Non-Steroidal Anti-Inflammatory Analgesics[NCT02417337] | Phase 2 | 170 participants (Actual) | Interventional | 2012-08-31 | Completed | ||
| Effect of Preoperative, Single-dose Diclofenac Potassium on Postoperative Endodontic Pain in Patients With Symptomatic Irreversible Pulpitis: A Double Blind Randomized Controlled Trial[NCT03341260] | Phase 2/Phase 3 | 70 participants (Actual) | Interventional | 2016-12-31 | Completed | ||
| Comparison of Postoperative Pain and Healing After Passive Ultrasonic Irrigation and Needle Irrigation in Patients With Apical Periodontitis: A Randomized Clinical Trial[NCT02913937] | 66 participants (Anticipated) | Interventional | 2017-02-28 | Not yet recruiting | |||
| Postendodontic Pain on Using Max-i-Probe vs NaviTip as Irrigation Needles: A Randomized Clinical Trial[NCT04119661] | 180 participants (Actual) | Interventional | 2012-07-31 | Completed | |||
| Effect Of Using XP Endo Finisher Versus Ultrasonic Activated Irrigation On Post-operative Pain In Single Visit Endodontic Treatment of Teeth With Symptomatic Irreversible Pulpitis: A Randomized Controlled Trial[NCT03096587] | 44 participants (Anticipated) | Interventional | 2017-04-15 | Recruiting | |||
| Effect of Transversus Abdominis Plane (TAP) Block as Postoperative Pain Management After Laparoscopic Colon Surgery[NCT01418144] | Phase 4 | 80 participants (Actual) | Interventional | 2010-08-31 | Completed | ||
| Comparison Between Dexamethasone and Ibuprofen on Postoperative Pain Prevention and Control Following Surgical Implant Placement: a Double-Blind, Parallel-Group, Placebo-Controlled Randomized Clinical Trial[NCT02763059] | Phase 4 | 132 participants (Actual) | Interventional | 2013-09-30 | Completed | ||
| Effect of Preoperative Single Dose of Sodium Ibuprofen Versus Placebo on Post-operative Pain for Patient With Symptomatic Irreversible Pulpitis Related to Mandibular Molar Teeth: Double Blind Randomized Controlled Trial[NCT04964622] | Phase 1/Phase 2 | 50 participants (Actual) | Interventional | 2021-12-01 | Completed | ||
| Non-Steroidal Anti-inflammatory Drugs (NSAIDS) vs. Tramadol in Pain Management After Transnasal Transsphenoidal Surgery Among Patients With Pituitary Adenomas: A Prospective Randomized Controlled Trial[NCT04611685] | 202 participants (Anticipated) | Interventional | 2020-10-31 | Recruiting | |||
| Randomized, Double-Blind, Placebo-Controlled Trial Comparing Opioid-Sparing and Opioid-Containing Analgesia Regimens Following Trans-sphenoidal Surgery for Pituitary Tumors[NCT02351700] | Phase 4 | 62 participants (Actual) | Interventional | 2015-02-01 | Completed | ||
| A Comparison of Analgesic and Respiratory Effects From Tapentadol Versus Oxycodone After Laparoscopic Hysterectomy.[NCT03314792] | Phase 4 | 86 participants (Actual) | Interventional | 2017-12-04 | Completed | ||
| Antiemetic and Analgesic Efficacy and Safety of Dexamethasone for Paediatric Adeno-tonsillectomy - A Randomised, Placebo-controlled, Double-blind, Dose-finding Study[NCT00403806] | Phase 4 | 215 participants (Actual) | Interventional | 2005-02-28 | Terminated (stopped due to drug-related harm) | ||
| Betamethasone (Betapred®) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy - a Randomized, Double-blind, Placebo-controlled Trial[NCT03783182] | Phase 4 | 100 participants (Anticipated) | Interventional | 2019-09-10 | Recruiting | ||
| Randomized Controlled Trial of the Use of Intramuscular Fentanyl for the Incision and Drainage of Abscess in the Emergency Department[NCT01881997] | Phase 4 | 0 participants (Actual) | Interventional | 2011-06-30 | Withdrawn (stopped due to IRB modifications made study impractical.) | ||
| Is Routine Packing of Cutaneous Abscesses Necessary?[NCT02822768] | 196 participants (Anticipated) | Interventional | 2016-08-31 | Recruiting | |||
| Is Routine Irrigation of Cutaneous Abscesses Necessary?[NCT01606657] | 201 participants (Actual) | Interventional | 2010-08-31 | Completed | |||
| A Randomized Comparison Study of Minimally Invasive Loop Drainage Versus Standard Incision and Drainage for Skin Abscesses in Children[NCT02443272] | 81 participants (Actual) | Interventional | 2014-09-30 | Completed | |||
| Assessment of the Analgesic Efficacy of Intravenous Ibuprofen in Biliary Colic[NCT02268955] | 22 participants (Actual) | Interventional | 2014-09-09 | Completed | |||
| A Prospective, Randomized, Double-blind Study Assessing the Efficacy of Intravenous (IV) Ibuprofen Versus IV Acetaminophen for the Treatment of Pain Following Orthopaedic Low Extremity Surgery[NCT03771755] | 62 participants (Actual) | Interventional | 2017-07-01 | Completed | |||
| Assessment of Preemptive Analgesic Effect of Caldolor® vs. Ofirmev® on Third Molar Surgery: A Prospective, Randomized, Double-blinded Clinical Trial[NCT02133326] | Phase 2 | 67 participants (Actual) | Interventional | 2014-03-31 | Active, not recruiting | ||
| A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Trial of Ibuprofen Injection (IVIb) for Treatment of Pain in the Post-Operative Adult Patients[NCT00225732] | Phase 3 | 319 participants (Actual) | Interventional | 2005-01-31 | Completed | ||
| Multicentre, Double-blind, Placebo-controlled, Randomized, Parallel Group Comparison of the Analgesic Effects of Different Maxigesic Doses Versus Acetaminophen, Ibuprofen and Placebo for the Teeth Extraction Pain[NCT01104844] | Phase 2 | 0 participants (Actual) | Interventional | Withdrawn (stopped due to The study was withdrawn due to administrative reason) | |||
| The Implications of Amantadine Sulphate Usage in Spine Deformities Corrective Surgeries Patients as Regard Its Effect on the Duration of Wake up Test and Postoperative Opioid Consumption[NCT03178708] | Phase 2/Phase 3 | 60 participants (Actual) | Interventional | 2017-08-01 | Completed | ||
| An Open-label, Single-dose, Pharmacokinetic Study of Acetaminophen/Naproxen Sodium Fixed Combination Tablets in Adolescents 12 to <17 Years of Age With Orthodontic Pain[NCT05844995] | Phase 1 | 30 participants (Anticipated) | Interventional | 2023-09-13 | Recruiting | ||
| Assessment of Postoperative Pain After Using Reciproc Versus One Shape NiTi Systems in Patients With Symptomatic Irreversible Pulpitis.[NCT02953912] | 54 participants (Anticipated) | Interventional | 2016-11-30 | Not yet recruiting | |||
| Influence of Different Methods of Removal of Double Antibiotic Paste as an Intracanal Medication on Post Operative Pain:a Randomized Clinical Trial[NCT04327453] | 30 participants (Anticipated) | Interventional | 2020-04-30 | Recruiting | |||
| Post Operative Pain After Removal of Calcium Hydroxide With Different Activation Techniques[NCT04324086] | 30 participants (Anticipated) | Interventional | 2020-04-01 | Recruiting | |||
| Comparative Evaluation of the Effect of Three Different Root-canal Medicaments on Post-operative Pain in Re-treatment Cases: a Randomized Clinical Trial[NCT05052814] | 120 participants (Actual) | Interventional | 2019-03-23 | Completed | |||
| Post-operative Analgesia in Elective, Soft-tissue Hand Surgery: A Randomized, Double Blind Comparison of Acetaminophen/Ibuprofen Versus Acetaminophen/Hydrocodone[NCT02029235] | Phase 4 | 72 participants (Actual) | Interventional | 2015-02-10 | Terminated (stopped due to Early termination due to slower than anticipated recruitment.) | ||
| Advancing the Multimodal Pathway: Investigating the Use of Sleep and Zolpidem in the Recovery After Shoulder Arthroplasty[NCT03269760] | Phase 1 | 122 participants (Actual) | Interventional | 2017-09-01 | Completed | ||
| The Scalp Block for Postoperative Pain Control in Craniosynostosis Surgery: a Case Control Study[NCT04133467] | 26 participants (Actual) | Observational | 2016-01-01 | Completed | |||
| Comparison of Pre-emptive Ibuprofen, Acetaminophen, and Placebo Administration in Reducing Local Anesthesia Injection Pain and Post-operative Pain in Primary Tooth Extraction. A Clinical Study[NCT03786029] | Phase 2/Phase 3 | 66 participants (Actual) | Interventional | 2019-04-01 | Completed | ||
| Hypoalgesic Effect of Median Nerve Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group[NCT02596815] | 51 participants (Actual) | Interventional | 2015-07-31 | Completed | |||
| Hypoalgesic Effect of Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group[NCT02595294] | 52 participants (Actual) | Interventional | 2015-07-31 | Completed | |||
| Hypoalgesic Effect of Median Nerve Neural Mobilization Versus Ibuprofen Pharmacologic Treatment in Patients With Cervicobrachial Pain[NCT02593721] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| The Effect of Premedication With Curcumin on Post-Operative Pain in Single Visit Endodontic Treatment of Acute Pulpitis in Mandibular Molars: A Randomized Controlled Trial[NCT04012424] | 44 participants (Actual) | Interventional | 2019-08-01 | Completed | |||
| Comparison of the Efficacy of Prophylactic Intraligamentary Injection of Piroxicam Versus Mepecaine for Management of Post-endodontic Pain in Posterior Teeth[NCT03006107] | 26 participants (Anticipated) | Interventional | 2016-12-31 | Not yet recruiting | |||
| Effect on Initial Endodontic Treatment on Postoperative Pain in Symptomatic Teeth With Pulpal Necrosis[NCT01870973] | 108 participants (Actual) | Interventional | 2013-03-31 | Completed | |||
| Music to Reduce Patient Reported Pain During Intrauterine Device (IUD) Placement in the Office[NCT05068245] | 96 participants (Actual) | Interventional | 2020-08-28 | Completed | |||
| Music as an Auxiliary Analgesic and Anxiolytic During First Trimester Abortion[NCT01013363] | 106 participants (Actual) | Interventional | 2009-09-30 | Completed | |||
| Auricular Acupuncture as Adjunct for Pain Management During First Trimester Uterine Aspiration.[NCT03391986] | 153 participants (Actual) | Interventional | 2017-09-09 | Completed | |||
| Immediate Postoperative Pain and Recovery Time After Pulpotomy Performed Under General Anaesthesia in Young Children[NCT03142672] | 90 participants (Actual) | Interventional | 2016-01-28 | Completed | |||
| Efficacy of Two Dental Local Anesthetics on the Oral Health-Related Quality of Life After Endodontic Treatment in the Symptomatic Mandibular Molars: A Double Blind Randomized Controlled Trial[NCT04787731] | Phase 4 | 100 participants (Anticipated) | Interventional | 2019-07-29 | Suspended (stopped due to COVID-19 and Personnel changes) | ||
| Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment[NCT05338671] | Phase 4 | 40 participants (Anticipated) | Interventional | 2021-09-29 | Active, not recruiting | ||
| Evaluation of the Efficiency of Intraligamentary + Buccal Infiltration Anesthesia and Inferior Alveolar Nerve Block + Buccal Infiltration Anesthesia in Symptomatic Mandibular Molars With Irreversible Pulpitis[NCT05839093] | 210 participants (Actual) | Interventional | 2021-12-21 | Completed | |||
| Adductor Canal Block in an Enhanced Recovery Program After Total Knee Arthroplasty[NCT03915522] | 140 participants (Anticipated) | Interventional | 2018-05-14 | Recruiting | |||
| Prospective, Randomized, Double-Blinded, Allocation Concealed Study Comparing the Efficacy of Liposomal Bupivacaine Over Standard Bupivacaine Plus Dexamethasone in Quadriceps Sparing Femoral Nerve Block and Wound Infiltration for Primary Total Knee Arthro[NCT02624856] | Phase 4 | 0 participants (Actual) | Interventional | 2015-11-30 | Withdrawn (stopped due to Lack of funding) | ||
| Femoral Versus Adductor Canal Continuous Peripheral Nerve Blocks for Knee Arthroplasty[NCT01759277] | Phase 4 | 80 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| Prospective, Double-blind, Randomized Study to Evaluate a Single Shot Adductor Canal Nerve Block Versus Femoral Nerve Block Combined With LIA (Local Infiltration Analgesia): Early Postoperative Period Functional Outcomes After Total Knee Replacement[NCT02218814] | 106 participants (Actual) | Interventional | 2014-08-31 | Completed | |||
| Adductor Canal Mid-thigh and Adductor Canal Distal Thigh: Is Cutaneous Sensory Blockade Similar Among Block Techniques?[NCT02788019] | Phase 4 | 52 participants (Actual) | Interventional | 2016-05-26 | Terminated (stopped due to Unable to complete the sample size needed for 80% power due to changes in surgical approach to adductor block usage.) | ||
| The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Total Knee Arthroplasty[NCT01261897] | Phase 4 | 40 participants (Anticipated) | Interventional | 2011-01-31 | Completed | ||
| Optimal Volume of Bupivacaine in Adductor Canal Nerve Block in Patients Undergoing Unilateral Cruciate Ligament Reconstruction Surgery[NCT02557386] | Phase 4 | 60 participants (Anticipated) | Interventional | 2016-01-31 | Recruiting | ||
| Ultrasound Guided Single Shot Adductor Canal Block (ACB) Versus Single Shot Femoral Nerve Block (FNB) for Postoperative Analgesia After Arthroscopic Anterior Cruciate Ligament (ACL) Reconstruction in Pediatrics[NCT03053401] | 52 participants (Actual) | Interventional | 2017-02-09 | Completed | |||
| Continuous Adductor Canal Block With Epidural Analgesia for Total Knee Arthroplasty: A Prospective, Randomized, Double-blinded, Placebo-Controlled Trial[NCT02121392] | 165 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| Evaluation of the Effects of Photobiomodulation on Orthodontic Movement of Molar Verticalization With Mini-implant: a Randomized Double-blind Protocol Study[NCT04036539] | 34 participants (Actual) | Interventional | 2020-11-15 | Completed | |||
| Single Dose Oral Celecoxib (With or Without Acetaminophen) for Acute Post-operative Pain Following Impacted Third Molar Surgery.[NCT04790812] | Phase 4 | 100 participants (Anticipated) | Interventional | 2021-04-22 | Recruiting | ||
| Ilioinguinal/Iliohypogastric vs. Quadratus Lumborum Nerve Blockade for Elective Open Inguinal Herniorrhaphy[NCT03007966] | Phase 2 | 60 participants (Actual) | Interventional | 2017-01-30 | Completed | ||
| Effect of Medial vs Traditional Approach to US-guided Transverse Abdominis Plane (TAP) Blocks on Analgesia After Open Inguinal Hernia Repair[NCT01589796] | 100 participants (Anticipated) | Interventional | 2012-04-30 | Recruiting | |||
| Does Preoperative Midazolam Dose Affect Postoperative Pain? - a Multicentric Observational Study in Open Inguinal Hernia Repair[NCT03499730] | 300 participants (Actual) | Observational | 2018-09-12 | Completed | |||
| Post-operative Pain Following Treatment Using the Gentlewave System[NCT03635515] | 87 participants (Actual) | Interventional | 2018-09-01 | Completed | |||
| Intravenous Acetaminophen as Adjuvant Therapy for Pain Control in Geriatric Hip Fracture Patients[NCT01520298] | Phase 3 | 0 participants (Actual) | Interventional | 2011-12-31 | Withdrawn (stopped due to Difficulty in recruiting subjects for the trial.) | ||
| Acupuncture for Postoperative Analgesia in Laparoscopic Surgery[NCT02940288] | 20 participants (Actual) | Interventional | 2016-09-30 | Completed | |||
| Acupuncture for Pain Management After Hip or Knee Arthroplasty[NCT00455182] | 0 participants (Actual) | Interventional | 2007-03-31 | Withdrawn (stopped due to Inability to enroll subjects who were willing to be randomized to control group) | |||
| The Effect of Auriculotherapy for Post-Operative Pain Management Following Rotator Cuff Surgery: A Randomized, Placebo-Controlled Study[NCT03860259] | 50 participants (Actual) | Interventional | 2020-01-24 | Completed | |||
| Open-Label Randomized Controlled Trial to Assess Preoperative Acupuncture for Patients Undergoing Total Knee or Hip Arthroplasty[NCT06099223] | 60 participants (Actual) | Interventional | 2022-03-21 | Completed | |||
| Self-Administration of Auricular Acupuncture Pilot Project[NCT04208659] | 12 participants (Actual) | Interventional | 2020-02-27 | Completed | |||
| Efficacy of Combined Ibuprofen and Acetaminophen Therapy Versus Ibuprofen Alone Versus Placebo Alone for Pain of Initial Orthodontic Wire Insertion: a Randomized Controlled Trial[NCT04059172] | Early Phase 1 | 375 participants (Anticipated) | Interventional | 2019-12-10 | Recruiting | ||
| A Multicentre Randomised Placebo-Controlled Trail of Ibuprofen for the Prevention of Ectopic Bone-Related Pain and Disability After Elective Hip Replacement Surgery (HIPAID)[NCT00145730] | Phase 4 | 1,000 participants | Interventional | 2002-02-28 | Completed | ||
| Analgesia Efficacy of Pre-operative and Post-operative PEC I/II Block for Bilateral Mastectomy With Reconstruction[NCT03653988] | 35 participants (Actual) | Interventional | 2019-03-12 | Completed | |||
| Comparison Between Serratus Anterior Plane Block, and Transversus Thoracic Plane Block Combined With Serratus Anterior Plane Block, for the Management of Post-mastecomy Pain.[NCT04375111] | 54 participants (Actual) | Interventional | 2021-06-15 | Completed | |||
| An Evaluation of Hydrocodone/Acetaminophen for Pain Control in First Trimester Surgical Abortion[NCT01330459] | Phase 4 | 121 participants (Actual) | Interventional | 2011-02-28 | Completed | ||
| An Evaluation of the Paracervical Block for Pain Control in First Trimester Surgical Abortion[NCT01094366] | Phase 4 | 121 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| Intravenous Versus Oral Acetaminophen for Postoperative Pain Control After Cesarean Delivery[NCT02487303] | 148 participants (Actual) | Interventional | 2015-03-17 | Completed | |||
| Efficiency Study About the Effect of Acupunctur on Postoperative Pain After Total Knee Arthroplastry[NCT02456116] | 90 participants (Anticipated) | Interventional | 2012-09-30 | Recruiting | |||
| The Effect of Ibuprofen, Paracetamol Versus Placebo on Pain During Local Anesthetic Injection and Following Dental Extraction in Primary Molars: A Randomized Clinical Trial[NCT03184649] | Phase 1/Phase 2 | 52 participants (Anticipated) | Interventional | 2017-05-01 | Enrolling by invitation | ||
| Oral Ibuprofen Plus Acetaminophen Versus Ibuprofen Alone for Acute Pain Reduction in Children[NCT04630834] | Phase 4 | 100 participants (Anticipated) | Interventional | 2021-03-30 | Recruiting | ||
| Millimeter Wave Therapy (MWT) Versus Placebo for Analgesia and Wound Healing After Elective Total Knee Arthroplasty - a Randomized Controlled Trial[NCT00233831] | Phase 2/Phase 3 | 80 participants | Interventional | 2004-03-31 | Completed | ||
| A Randomized Trial Comparing Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Outpatient Soft Tissue Hand Surgery[NCT03111186] | Phase 2 | 40 participants (Actual) | Interventional | 2017-04-24 | Completed | ||
| Fully Digital Guided Gingivectomy in Management of Gummy Smile: Evaluation of Accuracy and Patient Satisfaction[NCT05969132] | 18 participants (Anticipated) | Interventional | 2023-10-01 | Not yet recruiting | |||
| Clinical and Histomorphometric Analysis of Collagen Matrix Versus Connective Tissue Graft in Mucogingival Surgery in Orthodontic Patients. A Randomized, Controlled Clinical Trial[NCT03533933] | 5 participants (Anticipated) | Interventional | 2018-09-01 | Recruiting | |||
| Xenogeneic Collagen Matrix or Palatal Connective Tissue Graft With a Coronally Advanced Flap for the Treatment of Miller Class III Gingival Recessions[NCT03344315] | 20 participants (Actual) | Interventional | 2017-03-01 | Completed | |||
| Comparison of Graft Quality and Patient Morbidity Following Four Different Connective Tissue Graft Harvesting Techniques. A Randomized Controlled Feasibility Study[NCT03584906] | 60 participants (Actual) | Interventional | 2018-08-16 | Completed | |||
| Evaluation of the Effect of Ozonated Oil on the Healing of Palatal Donor Area of Free Gingival Grafts.[NCT05620550] | 28 participants (Anticipated) | Interventional | 2022-12-31 | Not yet recruiting | |||
| Healing After Connective Tissue Graft Harvesting in the Palatal Area With and Without Suture: A Randomized Controlled Trial[NCT04513886] | 36 participants (Actual) | Interventional | 2018-11-19 | Completed | |||
| Analgesic Effect of Pregabalin in Patients Undergoing Total Abdominal Hysterectomy[NCT01466101] | 0 participants (Actual) | Interventional | 2011-01-31 | Withdrawn (stopped due to PI left the institution. No subjects screened or enrolled.) | |||
| Effect of Preoperative Pregabalin on Propofol Induction Dose[NCT01158859] | Phase 4 | 50 participants (Anticipated) | Interventional | 2010-04-30 | Completed | ||
| Transumbilical Versus Lateral Transabdominal Removal of Benign Adnexal Masses Via Laparoscopy, a Randomized Trial[NCT02704663] | 42 participants (Actual) | Interventional | 2014-11-30 | Active, not recruiting | |||
| Preoperative Use of Pregabalin and Analgesia Levels After Laparoscopic Cholecystectomy[NCT01321801] | 50 participants (Actual) | Interventional | 2009-11-30 | Completed | |||
| Pretreatment Aceclofenac Effect on Pain and Analgesic Intake After Endodontic Treatment: A Randomized, Double-blind, Placebo-controlled Trial[NCT03335007] | Phase 2/Phase 3 | 70 participants (Actual) | Interventional | 2015-05-31 | Completed | ||
| Pre-Emptive Analgesic Effects of a Selective COX-2 Inhibitor (Rofecoxib) in the Oral Surgery Model[NCT00026819] | Phase 2 | 150 participants | Interventional | 2001-11-30 | Completed | ||
| Evaluation of Postoperative Edema and Pain Following Third Molar Extraction With Application of Pulsed Electromagnetic Field (PEMF) Therapy[NCT02376946] | 49 participants (Actual) | Interventional | 2014-01-31 | Terminated (stopped due to Sponsor decision) | |||
| Assessment of the Operative Course in Connection With Removal of Lower Third Molars With Particular Consideration to the Occurence of Pain and Swelling[NCT00805298] | 154 participants (Actual) | Interventional | 2008-08-31 | Completed | |||
| Impact of Low-dose Dexmedetomidine on Outcomes of Elderly Admitted to ICU After Noncardiac Surgery: a Randomized Controlled Trial[NCT04204798] | 1,410 participants (Anticipated) | Interventional | 2020-08-28 | Recruiting | |||
| Comparing Narcotics With Non-steroidal Anti-inflammatory Drugs (NSAIDS) Post-operatively in Pediatric Patients Undergoing Adenotonsillectomy[NCT02296840] | Phase 4 | 45 participants (Actual) | Interventional | 2014-11-30 | Terminated | ||
| Cytokine Responses to Acute Inflammation in the Oral Surgery Model[NCT00006175] | 160 participants | Observational | 2000-08-31 | Completed | |||
| Dextromethorphan as a Novel Non-opioid Adjunctive Agent for Pain Control in Medication Abortion: a Randomized Controlled Trial[NCT03480009] | Phase 3 | 156 participants (Actual) | Interventional | 2018-07-28 | Completed | ||
| Towards Predicting the Analgesic Response to Ibuprofen Following Third-molar Extraction[NCT03893175] | Phase 1 | 86 participants (Actual) | Interventional | 2019-05-10 | Completed | ||
| Predicting Perioperative Opioid Adverse Effects and Personalizing Analgesia in Children: A Multicenter Pharmacogenetic Study[NCT01495611] | 1,000 participants (Actual) | Observational | 2010-11-30 | Completed | |||
| The Incidence of Postoperative Pain After Using Different Types of Sealers (A Randomized Clinical Trial)[NCT05841290] | 40 participants (Anticipated) | Interventional | 2023-05-31 | Not yet recruiting | |||
| Effect of Preoperative, Single-dose Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain in Patients With Symptomatic Apical Periodontitis: A Double-Blind Randomized Controlled Trial.[NCT03033147] | 72 participants (Actual) | Interventional | 2019-10-18 | Completed | |||
| Effect of Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain in Patients With Symptomatic Apical Periodontitis: A Randomized Controlled Trial[NCT03007342] | 78 participants (Anticipated) | Interventional | 2017-01-31 | Not yet recruiting | |||
| Evaluation of the Efficacy of the Photobiomodulation on the Pelvi-perineal Pain in Patients in Immediate Post-partum Situation[NCT04896034] | 677 participants (Anticipated) | Interventional | 2021-05-06 | Recruiting | |||
| Evaluation of Alveolar Bone Preservation After Early Molar Extraction Using Photobiomodulation Combined With Grafting With Scaffold Biomaterial: Clinical, Randomized, Triple-blind Study.[NCT06164626] | Phase 1 | 60 participants (Anticipated) | Interventional | 2023-12-10 | Recruiting | ||
| Evaluation of Alveolar Bone Preservation After Molar Extraction Using Photobiomodulation Combined With Grafting With Scaffold Biomaterial: Clinical, Randomized, Triple-blind Study.[NCT06150456] | Phase 1 | 60 participants (Actual) | Interventional | 2022-05-24 | Completed | ||
| Efficacy of Steroids on Functional Outcomes After Musculoskeletal Injuries of the Hand[NCT05003596] | Phase 2/Phase 3 | 60 participants (Anticipated) | Interventional | 2021-09-01 | Not yet recruiting | ||
| Ibuprofen vs. Codeine. Is One Better for Post-operative Pain Relief Following Reduction of Paediatric Forearm Fractures?[NCT01605240] | 50 participants (Anticipated) | Interventional | 2012-07-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"A Pain Intensity Difference (PID) is the difference between the Visual Analogue Scale (VAS) pain intensity score recorded at baseline and a score recorded at any time after the first dose of study medication. Taken together, a patient's PID scores capture the pain relief profile attributable to the assigned study medication. A high PID score indicates a better pain relief experienced.~The extent of pain relief can then be calculated by the Area Under the Curve the PID scores (also referred to as the Sum of Pain Intensity Differences [SPID]). SPID48 scores were adjusted by the time interval from baseline to the final VAS score used in the SPID, using the following formula:~Time-adjusted SPID48 (mm) = SPID (mm*hr) / Time (hr) In the event that a patient required rescue medication, the SPID was calculated up until the first Pre-Rescue VAS pain assessment (inclusive)." (NCT02689063)
Timeframe: 48 hours after the first dose
| Intervention | score on a scale (Mean) |
|---|---|
| Maxigesic IV | 23.4 |
| IV Acetaminophen | 10.4 |
| IV Ibuprofen | 9.5 |
| Placebo IV | -1.3 |
"At the end of 48 hours study period, participants will be asked to How do you rate the study medication? on a 5 point categorical scale:~Poor~Fair~Good~Very Good~Excellent The high score means the participants believed that a better treatment for pain relief received." (NCT02689063)
Timeframe: 48 hrs after the first dose
| Intervention | Participants (Count of Participants) |
|---|---|
| Maxigesic IV | 24 |
| IV Acetaminophen | 5 |
| IV Ibuprofen | 8 |
| Placebo IV | 1 |
"VAS Pain intensity difference (PID) at each scheduled assessment time point after Time 0.~A Pain Intensity Difference (PID) is the difference between the Visual Analogue Scale (VAS) pain intensity score recorded at baseline and a score recorded at any time after the first dose of study medication. Taken together, a patient's PID scores capture the pain relief profile attributable to the assigned study medication. A high PID score indicates a better pain relief experienced." (NCT02689063)
Timeframe: 48 hours after the first dose
| Intervention | score on a scale (Mean) |
|---|---|
| Maxigesic IV | 52.50 |
| IV Acetaminophen | 38.95 |
| IV Ibuprofen | 45.04 |
| Placebo IV | 37.24 |
"VAS Pain intensity score at each scheduled assessment time point VAS pain intensity score-marking on a 100 mm VAS scale with anchors for no pain (0 mm) and worst pain imaginable (100 mm). A high VAS score indicates a more intensive pain level experienced." (NCT02689063)
Timeframe: 48 hours after the first dose
| Intervention | score on a scale (Mean) |
|---|---|
| Maxigesic IV | 18.43 |
| IV Acetaminophen | 29.28 |
| IV Ibuprofen | 27.21 |
| Placebo IV | 28.22 |
Treatment-emergent Adverse events coded to MedDRA v 20.0 Preferred Term and System Organ Class Code were tabulated as the counts and percentages by treatment group. (NCT02689063)
Timeframe: Day 7
| Intervention | Participants (Count of Participants) |
|---|---|
| Maxigesic IV | 52 |
| IV Acetaminophen | 45 |
| IV Ibuprofen | 58 |
| Placebo IV | 39 |
"Peak Pain Relief was assessed on Pain Relief scores (on a 5 point categorical rating-please see outcome measure description No. 7) recorded up until the first dose of rescue (First Pre-Rescue Pain Relief score inclusive).~The percentage of participants who achieve the peak pain relief was summarized." (NCT02689063)
Timeframe: 48 hours after the first dose
| Intervention | Participants (Count of Participants) |
|---|---|
| Maxigesic IV | 22 |
| IV Acetaminophen | 11 |
| IV Ibuprofen | 4 |
| Placebo IV | 3 |
"Pain relief score was assessed on a 5-point categorical scale at each scheduled time point after Time 0:~0 = No pain relief (the pain is the same, or worse, than the starting pain)~= A little pain relief (the pain is less than half gone)~= some pain relief (the pain is about half gone)~= A lot pain relief (the pain is more than half gone)~= Complete pain relief (the pain is completely gone)~Assessed at scheduled time points:~5, 10, 15, 30, 45 minutes, 1, 1.5, 2, 3, 4, 5, 6 hours after the first dose of the study drug~Immediately before and 2 hours after each subsequent dose (doses 2-8) of the study drug while awake~At the end of 48 hours of double-blind treatment period~Immediately before taking each dose of the rescue medication if additional analgesia is required.~At the time of withdrawal (if applicable)" (NCT02689063)
Timeframe: 48 hours after the first dose
| Intervention | Participants (Count of Participants) |
|---|---|
| Maxigesic IV | 29 |
| IV Acetaminophen | 7 |
| IV Ibuprofen | 16 |
| Placebo IV | 4 |
The percentage of participants who used at lease one dose of rescue medication was summarized in each treatment group (NCT02689063)
Timeframe: 48 hrs after the first dose
| Intervention | Participants (Count of Participants) |
|---|---|
| Maxigesic IV | 56 |
| IV Acetaminophen | 70 |
| IV Ibuprofen | 70 |
| Placebo IV | 48 |
"Time to peak pain relief-Peak Pain Relief was assessed on Pain Relief scores recorded up until the first dose of rescue (First Pre-Rescue Pain Relief score inclusive). Time for participants who experienced peak pain relief was summarized.~Note: For the reader to interpret this outcome measure, a very short Time to Peak Pain Relief indicates the absence of analgesic effect for a treatment because peak pain relief was determined prior to the first dose of rescue medication (or 48 hours if no rescue medication was used)." (NCT02689063)
Timeframe: 48 hrs after the first dose
| Intervention | hours (Mean) |
|---|---|
| Maxigesic IV | 4.00 |
| IV Acetaminophen | 2.46 |
| IV Ibuprofen | 1.47 |
| Placebo IV | 0.91 |
Time to first use of rescue medication (duration of analgesia) (NCT02689063)
Timeframe: 48 hrs
| Intervention | hours (Mean) |
|---|---|
| Maxigesic IV | 12.98 |
| IV Acetaminophen | 5.62 |
| IV Ibuprofen | 3.09 |
| Placebo IV | 2.92 |
"Two-stopwatch method~Start two stopwatches ('Stopwatch A' and 'Stopwatch B') at the same time that the infusion of study drug is initiated. This is Time 0.~The participant is given 'Stopwatch A' and instructed to Stop 'Stopwatch A' when you first feel any pain relief whatsoever. This does not mean you feel completely better, although you might, but when you first feel any relief in the pain you have now. (Perceptible Pain Relief)~When the participant stops the 'Stopwatch A', the participant then was asked Do you consider the pain relief you experienced meaningful?~If the participant answered No, then the participant was given the Stopwatch B and instructed to Stop 'Stopwatch B' when you feel the pain relief is meaningful to you (Meaningful Pain Relief)~If the subject did not experience perceptible pain relief, they would retain 'Stopwatch A' for the entire 6 hour evaluation period." (NCT02689063)
Timeframe: 6 hours
| Intervention | minutes (Median) |
|---|---|
| Maxigesic IV | 9.4 |
| IV Acetaminophen | 23.9 |
| IV Ibuprofen | 13.8 |
| Placebo IV | 0 |
"Time adjusted SPID-6, SPID-12, SPID-24 were derived in a similar manner to the Time-adjusted SPID-48 (i.e. up until the first Pre-Rescue VAS inclusive). Please see the primary outcome measure descriptions.~Each of these variables were derived from VAS (Visual Analogue Scale) scores recorded prior to the first dose of rescue medication in the first 6 (to calculate SPID6), 12 (to calculate SPID12) or 24 hours (to calculate SPID24) of the study.~VAS pain intensity scores were obtained by marking on a 100 mm VAS scale with anchors for no pain (0 mm) and worst pain imaginable (100 mm). The VAS was completed at rest." (NCT02689063)
Timeframe: 6, 12, 24 hours after the first dose
| Intervention | score on a scale (Mean) | ||
|---|---|---|---|
| SPID 6 | SPID 12 | SPID 24 | |
| IV Acetaminophen | 10.13 | 9.42 | 9.59 |
| IV Ibuprofen | 9.01 | 8.44 | 8.64 |
| Maxigesic IV | 20.10 | 20.63 | 21.99 |
| Placebo IV | -1.49 | -1.66 | -1.54 |
Total use of rescue analgesia over 0 to 24 hours and over 0 to 48 hours (NCT02689063)
Timeframe: 24, 48 hrs after the first dose
| Intervention | mg (Mean) | |
|---|---|---|
| Total Dose in 48 hrs | Total Dose in 24 hrs | |
| IV Acetaminophen | 33.1 | 23.7 |
| IV Ibuprofen | 32.4 | 22.1 |
| Maxigesic IV | 22.9 | 17.2 |
| Placebo IV | 44.7 | 29.6 |
"Total Pain Relief (TOTPAR) is a measure of total Area Under the Curve of Pain Relief scores. In the event that a patient required rescue medication, the TOTPAR endpoints were calculated using Pain Relief Assessments recorded prior to the first dose of rescue (i.e. inclusive of the first pre-rescue Pain Relief score).~Pain relief scores were obtained by marking on a 5-point categorical rating at scheduled time points.~The high score means more pain relief experienced:~0 = No pain relief (the pain is the same, or worse, than the starting pain)~= A little pain relief (the pain is less than half gone)~= some pain relief (the pain is about half gone)~= A lot pain relief (the pain is more than half gone)~= Complete pain relief (the pain is completely gone) Each of these variables were derived from pain relief scores recorded prior to the first dose of rescue medication in the first 6 (0-48), 12 (0-48), 24 (0-48) or 48 (0-48) hours of the study." (NCT02689063)
Timeframe: 6, 12, 24, 48 hours after the first dose
| Intervention | score on a scale*hour (Mean) | |||
|---|---|---|---|---|
| TOTPAR 6 | TOTPAR 12 | TOTPAR 24 | TOTPAR 48 | |
| IV Acetaminophen | 4.59 | 6.74 | 8.66 | 13.28 |
| IV Ibuprofen | 3.34 | 4.46 | 6.51 | 11.95 |
| Maxigesic IV | 6.84 | 11.86 | 22.13 | 43.98 |
| Placebo IV | 1.60 | 1.82 | 2.49 | 4.51 |
Pain score recorded 24-hrs after the ERCP was performed as recorded on a 10-point Likert pain scale (0= lowest value, no pain, 10=highest value, severe pain) (NCT02241512)
Timeframe: pre-procedural, 24 hours
| Intervention | score on a Likert pain scale (Mean) |
|---|---|
| Ibuprofen | 1.1 |
| Placebo | 3.1 |
Number of patients with increased pain scores after the procedure (NCT02241512)
Timeframe: pre-procedural, 24 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Ibuprofen | 1 |
| Placebo | 11 |
Number of patients who develop post-ERCP bleeding (NCT02241512)
Timeframe: 2 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Ibuprofen | 2 |
| Placebo | 0 |
Number of patients who develop post-ERCP pancreatitis (NCT02241512)
Timeframe: 2 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Ibuprofen | 2 |
| Placebo | 5 |
Outcome measure based on morphine equivalent dosage comparing the two groups (NCT02152163)
Timeframe: morphine equivalent dosage in over 48 hours after admission
| Intervention | morphine equivalent dosage, mg (Least Squares Mean) |
|---|---|
| IV Ibuprofen 800 mg | 74.9 |
| IV Saline | 97.8 |
Duration of pain relief was defined as the time between the administration of first dose of trial medication and first dose of rescue medication or second dose of trial medication, whichever was first. Duration of pain relief was censored at 8 hours. (NCT01929031)
Timeframe: 8 hours
| Intervention | hours (Median) |
|---|---|
| Placebo | 1.63 |
| Caffeine | 2.08 |
| Ibuprofen | 7.11 |
| Ibuprofen/Caffeine | 7.33 |
Time to meaningful pain relief was captured by a stopwatch, which was started by the study staff immediately after the administration of the first dose of trial medication and which was to be stopped by the patient as soon as he/she felt meaningful pain relief. Time to meaningful pain relief was censored at 8 hours. (NCT01929031)
Timeframe: 8 hours
| Intervention | hours (Median) |
|---|---|
| Placebo | NA |
| Caffeine | NA |
| Ibuprofen | 1.78 |
| Ibuprofen/Caffeine | 1.13 |
SPRID0-2h: Time-weighted sum of PAR and PID from 0 to 2 hours, score range: -10 (worst) to 28 (best). PI was assessed on a 0-10 numerical pain rating scale (NPRS), where 0=no pain and 10=worst possible pain, pre-dose and at 0.25,0.5,0.75,1,1.5 and 2 hours; PAR was assessed on a 5-point verbal rating scale (VRS) (0=none to 4=complete) at the same post-dose time points. Time-weights were equal to the elapsed time (hour) between the time point of interest and the preceding time point. All PAR and pain intensity (PI) assessments completed after the patient had taken rescue medication or the second dose of study medication, whichever was first, until hour 2 was considered missing. Last observation carried forward (LOCF) was used with the last completed PI/PAR assessments prior to first rescue/second study medication, whichever was first, to impute missing values up to 2 hours. (NCT01929031)
Timeframe: 0 to 2 hours
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| Placebo | 2.059 |
| Caffeine | 2.612 |
| Ibuprofen | 6.990 |
| Ibuprofen/Caffeine | 10.584 |
SPRID0-8h: Time-weighted sum of PAR and PID from 0 to 8 hours, score range: -40 (worst) to 112 (best). PI was assessed on a 0-10 numerical pain rating scale (NPRS), where 0=no pain and 10=worst possible pain, pre-dose and at 0.25,0.5,0.75,1,1.5,2,3,4,5, 6,7 and 8 hours; PAR was assessed on a 5-point verbal rating scale (VRS) (0=none to 4=complete) at the same post-dose time points. Time-weights were equal to the elapsed time (hour) between the time point of interest and the preceding time point. All PAR and pain intensity (PI) assessments completed after the patient had taken rescue medication or the second dose of study medication, whichever was first, until hour 8 were considered missing. Last observation carried forward (LOCF) was used with the last completed PI/PAR assessments prior to first rescue/second study medication, whichever was first, to impute missing values up to 8 hours. (NCT01929031)
Timeframe: 0 to 8 hours
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| Placebo | 10.554 |
| Caffeine | 15.824 |
| Ibuprofen | 40.165 |
| Ibuprofen/Caffeine | 52.291 |
Participant global evaluation of study medication was performed at the 12-hour time point or immediately before taking the rescue medication. It was scored on a 6-point categorical scale where 0= Very poor, 1= Poor, 2= Fair, 3= Good, 4= Very Good and 5= Excellent. (NCT01559259)
Timeframe: 12 hour
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | 1.0 |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 3.8 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 3.4 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 3.6 |
| Ibuprofen 400 mg | 3.5 |
Participants evaluated the time to first perceptible relief (confirmed by meaningful relief) by stopping the first stopwatch labelled 'first perceptible relief' at the moment they first began to experience any pain relief, if the participant also achieved meaningful relief by the end of the study. Stopwatch was active up to 12 hours after dosing or until stopped by the participant, or until the participant dropped out due to treatment failure (defined as participant taking rescue medication, or discontinuing due to lack of efficacy) prior to depressing the first stopwatch or until the time of withdrawal (discontinuation). (NCT01559259)
Timeframe: From 0 hour up to 12 hours post-dose
| Intervention | minutes (Median) |
|---|---|
| Placebo | NA |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 18.5 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 22.8 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 18.5 |
| Ibuprofen 400 mg | 24.9 |
"Participants evaluated time to meaningful relief by stopping a second stopwatch labelled as meaningful relief at the moment they first began to experience meaningful relief. Stopwatch was active up to 12 hours after dosing or until stopped by participant, or participant became treatment failure prior to depressing the second stopwatch. Treatment failure was defined as participant taking rescue medication, or discontinuing due to lack of efficacy." (NCT01559259)
Timeframe: From 0 hour up to 12 hours post-dose
| Intervention | minutes (Median) |
|---|---|
| Placebo | NA |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 44.5 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 54.1 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 45.9 |
| Ibuprofen 400 mg | 56.2 |
Time to treatment failure was defined as the time interval from the study drug administration up to the first documentation of treatment failure. Treatment failure was defined as taking the rescue medication or discontinuation of the participants from the study due to lack of efficacy, whichever came first. Participants were censored at 12 hours or at their final assessment time, whichever came first. (NCT01559259)
Timeframe: From 0 hour up to 12 hours post-dose
| Intervention | hours (Median) |
|---|---|
| Placebo | 1.6 |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 9.7 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 10.1 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 11.1 |
| Ibuprofen 400 mg | 10.4 |
SPRID4:Time-weighted sum of pain relief rating (PRR) and pain intensity difference (PID) based on 4 point categorical severity rating scale (PRID) over 8 hours.SPRID 0-8 score range:-8 (worst score) to 56 (best score).PRID: sum of PRR and PID at each time point.PRID score range:-1= worst score to 7= best score.PID4 was calculated by subtracting the pain intensity score at given post-dose time points (pain severity score range: 0 [none] to 3 [severe]) from the baseline pain intensity scores (score range: 2 =moderate pain to 3 = severe pain; as participants with baseline pain score of at least moderate were included in study). Total possible score range for PID: -1 (worst score) to 3 (best score).PRR assessed on 5-point categorical scale with range:0 =no relief to 4 =complete relief. (NCT01559259)
Timeframe: From 0 hour up to 8 hours post-dose
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | 5.0 |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 30.8 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 29.6 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 31.7 |
| Ibuprofen 400 mg | 28.8 |
Percentage of participants with confirmed first perceptible relief was reported. Participants evaluated the time to first perceptible relief (confirmed by meaningful relief) by stopping the first stopwatch labelled 'first perceptible relief' at the moment they first began to experience any pain relief, if the participant also achieved meaningful relief by the end of the study. Stopwatch was active up to 12 hours after dosing or until stopped by the participant, or until the participant dropped out due to treatment failure prior to depressing the first stopwatch or until the time of withdrawal (discontinuation). Treatment failure was defined as participant taking rescue medication, or discontinuing due to lack of efficacy. (NCT01559259)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 hours post-dose
| Intervention | percentage of participants (Number) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hour | 0.5 hour | 1 hour | 1.5 hour | 2 hour | 3 hour | 4 hour | 5 hour | 6 hour | 7 hour | 8 hour | 9 hour | 10 hour | 11 hour | 12 hour | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 26.7 | 73.3 | 88.9 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 18.3 | 66.7 | 83.9 | 86.0 | 88.2 | 88.2 | 88.2 | 88.2 | 88.2 | 88.2 | 88.2 | 88.2 | 88.2 | 88.2 | 88.2 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 28.1 | 77.5 | 88.8 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 |
| Ibuprofen 400 mg | 19.6 | 63.0 | 80.4 | 84.8 | 85.9 | 85.9 | 85.9 | 85.9 | 85.9 | 85.9 | 85.9 | 85.9 | 85.9 | 85.9 | 85.9 |
| Placebo | 3.3 | 10.0 | 16.7 | 16.7 | 20.0 | 20.0 | 20.0 | 20.0 | 20.0 | 20.0 | 20.0 | 20.0 | 20.0 | 20.0 | 20.0 |
"Percentage of participants with meaningful relief was reported. Participants evaluated time to meaningful relief by stopping a second stopwatch labeled meaningful relief at the moment they first began to experience meaningful relief. Stopwatch was active up to 12 hours after dosing or until stopped by participant, or participant became treatment failure prior to depressing the second stopwatch. Treatment failure was defined as participant taking rescue medication, or discontinuing due to lack of efficacy." (NCT01559259)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 hours post-dose
| Intervention | percentage of participants (Number) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hours | 0.5 hours | 1 hour | 1.5 hours | 2 hours | 3 hours | 4 hours | 5 hours | 6 hours | 7 hours | 8 hours | 9 hours | 10 hours | 11 hours | 12 hours | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 1.1 | 33.3 | 65.6 | 81.1 | 85.6 | 90.0 | 90.0 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 1.1 | 23.7 | 54.8 | 69.9 | 77.4 | 81.7 | 83.9 | 84.9 | 86.0 | 87.1 | 88.2 | 88.2 | 88.2 | 88.2 | 88.2 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 3.4 | 22.5 | 67.4 | 77.5 | 84.3 | 88.8 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 |
| Ibuprofen 400 mg | 1.1 | 13.0 | 54.3 | 66.3 | 73.9 | 80.4 | 81.5 | 82.6 | 83.7 | 84.8 | 85.9 | 85.9 | 85.9 | 85.9 | 85.9 |
| Placebo | 0.0 | 0.0 | 3.3 | 6.7 | 10.0 | 10.0 | 13.3 | 13.3 | 16.7 | 16.7 | 16.7 | 16.7 | 20.0 | 20.0 | 20.0 |
Treatment failure was defined as taking the rescue medication or discontinuation of the participants from the study due to lack of efficacy, whichever came first. Participants were censored at 12 hours or at their final assessment time, whichever came first. Percentage of participants who had treatment failure were reported. (NCT01559259)
Timeframe: 1.5, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 hours post-dose
| Intervention | percentage of participants (Number) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1.5 hour | 2 hour | 3 hour | 4 hour | 5 hour | 6 hour | 7 hour | 8 hour | 9 hour | 10 hour | 11 hour | 12 hour | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 2.2 | 2.2 | 2.2 | 3.3 | 4.4 | 8.9 | 17.8 | 28.9 | 40.0 | 51.1 | 57.8 | 64.4 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 2.2 | 6.5 | 8.6 | 9.7 | 14.0 | 18.3 | 20.4 | 23.7 | 33.3 | 46.2 | 53.8 | 57.0 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 4.5 | 5.6 | 6.7 | 7.9 | 10.1 | 14.6 | 15.7 | 25.8 | 36.0 | 42.7 | 48.3 | 50.6 |
| Ibuprofen 400 mg | 5.4 | 10.9 | 13.0 | 15.2 | 15.2 | 20.7 | 27.2 | 32.6 | 35.9 | 45.7 | 53.3 | 55.4 |
| Placebo | 43.3 | 73.3 | 80.0 | 80.0 | 80.0 | 80.0 | 80.0 | 80.0 | 80.0 | 80.0 | 80.0 | 80.0 |
PID11: baseline pain severity score minus pain severity score at a given time point. Pain intensity was assessed on an 11-point numerical pain severity rating scale. PID11 was calculated by subtracting the pain intensity score at given post-dose time points (pain severity score range: 0 =no pain to 10 =worst possible pain) from the baseline pain intensity scores (score range: 5 =moderate pain to 10 =worst possible pain; as participants with baseline pain score of at least moderate were included in study). Total possible score range for PID11: -5 (worst score) to 10 (best score). (NCT01559259)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 hours post-dose
| Intervention | units on a scale (Mean) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hour | 0.5 hour | 1 hour | 1.5 hour | 2 hour | 3 hour | 4 hour | 5 hour | 6 hour | 7 hour | 8 hour | 9 hour | 10 hour | 11 hour | 12 hour | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 1.0 | 3.0 | 4.7 | 5.3 | 5.5 | 5.7 | 5.5 | 5.3 | 4.6 | 3.9 | 3.1 | 2.5 | 1.9 | 1.6 | 1.1 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 0.8 | 2.5 | 4.2 | 5.0 | 5.3 | 5.5 | 5.4 | 5.1 | 4.8 | 4.2 | 3.5 | 2.7 | 2.1 | 1.7 | 1.5 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 0.9 | 2.6 | 4.5 | 5.3 | 5.6 | 5.7 | 5.6 | 5.3 | 5.0 | 4.2 | 3.2 | 2.8 | 2.5 | 2.0 | 1.7 |
| Ibuprofen 400 mg | 0.4 | 1.7 | 3.8 | 4.6 | 5.0 | 5.2 | 5.1 | 4.9 | 4.4 | 3.9 | 3.5 | 2.9 | 2.5 | 2.2 | 1.9 |
| Placebo | 0.1 | 0.2 | 0.1 | 0.0 | -0.1 | 0.1 | 0.3 | 0.2 | 0.4 | 0.3 | 0.3 | 0.5 | 0.6 | 0.6 | 0.7 |
PID4: baseline pain severity score minus pain severity score at a given time point. Pain intensity was assessed on a 4-point categorical pain severity rating scale. PID4 was calculated by subtracting the pain intensity score at given post-dose time points (pain severity score range: 0 [no pain] to 3 [worst possible pain]) from the baseline pain intensity scores (score range: 2 =moderate pain to 3 =worst possible pain; as participants with baseline pain score of at least moderate were included in study). Total possible score range for PID4: -1 (worst score) to 3 (best score). (NCT01559259)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 hours post-dose
| Intervention | units on a scale (Mean) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hour | 0.5 hour | 1 hour | 1.5 hour | 2 hour | 3 hour | 4 hour | 5 hour | 6 hour | 7 hour | 8 hour | 9 hour | 10 hour | 11 hour | 12 hour | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 0.3 | 0.9 | 1.5 | 1.6 | 1.7 | 1.7 | 1.7 | 1.6 | 1.4 | 1.2 | 0.9 | 0.8 | 0.6 | 0.5 | 0.3 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 0.2 | 0.7 | 1.2 | 1.5 | 1.6 | 1.6 | 1.6 | 1.5 | 1.4 | 1.2 | 1.0 | 0.7 | 0.6 | 0.5 | 0.4 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 0.3 | 0.8 | 1.4 | 1.6 | 1.7 | 1.7 | 1.7 | 1.6 | 1.6 | 1.3 | 1.0 | 0.8 | 0.7 | 0.6 | 0.4 |
| Ibuprofen 400 mg | 0.2 | 0.5 | 1.1 | 1.4 | 1.5 | 1.6 | 1.6 | 1.5 | 1.3 | 1.2 | 1.0 | 0.8 | 0.7 | 0.6 | 0.5 |
| Placebo | 0.1 | 0.1 | 0.1 | 0.1 | 0.0 | 0.1 | 0.1 | 0.1 | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 | 0.3 |
"Participants answered a question: how much relief do you have from your starting pain? on a 5-point categorical pain relief rating scale. Scale ranges from 0= no relief to 4= complete relief." (NCT01559259)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 hours post-dose
| Intervention | units on a scale (Mean) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hour | 0.5 hour | 1 hour | 1.5 hour | 2 hour | 3 hour | 4 hour | 5 hour | 6 hour | 7 hour | 8 hour | 9 hour | 10 hour | 11 hour | 12 hour | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 0.6 | 1.7 | 2.5 | 2.8 | 2.9 | 2.9 | 2.9 | 2.7 | 2.5 | 2.1 | 1.7 | 1.4 | 1.2 | 0.9 | 0.8 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 0.5 | 1.5 | 2.3 | 2.6 | 2.7 | 2.8 | 2.7 | 2.6 | 2.4 | 2.2 | 1.9 | 1.5 | 1.2 | 1.0 | 0.9 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 0.7 | 1.6 | 2.5 | 2.8 | 2.9 | 3.0 | 2.9 | 2.8 | 2.7 | 2.3 | 1.9 | 1.7 | 1.5 | 1.3 | 1.1 |
| Ibuprofen 400 mg | 0.4 | 1.1 | 2.1 | 2.5 | 2.6 | 2.7 | 2.7 | 2.6 | 2.4 | 2.1 | 1.9 | 1.7 | 1.4 | 1.3 | 1.2 |
| Placebo | 0.2 | 0.3 | 0.4 | 0.4 | 0.4 | 0.5 | 0.5 | 0.5 | 0.6 | 0.6 | 0.6 | 0.6 | 0.6 | 0.6 | 0.6 |
PRID4: sum of PID and PRR at each post-dose time points up to 12 hours. Score range for PRID: -1(worst score) to 7(best score). PID was calculated by subtracting the pain intensity score at given post-dose time points (pain severity score range: 0 [no pain] to 3 [worst possible pain]) from the baseline pain intensity scores (score range: 2 =moderate pain to 3 =worst possible pain; as participants with baseline pain score of at least moderate were included in study). Total possible score range for PID4: -1 (worst score) to 3 (best score). PRR was assessed on a 5-point categorical pain relief rating scale which ranges from 0 =no relief to 4 =complete relief. (NCT01559259)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 hours post-dose
| Intervention | units on a scale (Mean) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hour | 0.5 hour | 1 hour | 1.5 hour | 2 hour | 3 hour | 4 hour | 5 hour | 6 hour | 7 hour | 8 hour | 9 hour | 10 hour | 11 hour | 12 hour | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 1.0 | 2.6 | 4.0 | 4.5 | 4.6 | 4.6 | 4.5 | 4.3 | 3.8 | 3.3 | 2.7 | 2.2 | 1.7 | 1.4 | 1.1 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 0.7 | 2.2 | 3.6 | 4.1 | 4.3 | 4.4 | 4.3 | 4.1 | 3.9 | 3.4 | 2.9 | 2.2 | 1.7 | 1.5 | 1.2 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 1.0 | 2.4 | 3.9 | 4.5 | 4.7 | 4.7 | 4.6 | 4.4 | 4.2 | 3.6 | 2.8 | 2.5 | 2.2 | 1.9 | 1.6 |
| Ibuprofen 400 mg | 0.6 | 1.6 | 3.2 | 3.9 | 4.2 | 4.3 | 4.2 | 4.1 | 3.7 | 3.3 | 3.0 | 2.5 | 2.1 | 1.9 | 1.7 |
| Placebo | 0.3 | 0.3 | 0.5 | 0.5 | 0.4 | 0.6 | 0.7 | 0.6 | 0.8 | 0.7 | 0.7 | 0.8 | 0.8 | 0.9 | 0.9 |
Pain intensity was assessed on an 11-point numerical pain severity rating scale. SPID11: Time-weighted sum of PID scores over 12 hours. SPID11 score range was -10 (worst score) to 20 (best score) for SPID 0-2, -30 (worst score) to 60 (best score) for SPID 0-6, -40 (worst score) to 80 (best score) for SPID 0-8, -60 (worst score) to 120 (best score) for SPID 0-12. PID was calculated by subtracting the pain intensity score at given post-dose time points (pain severity score range: 0 =no pain to 10 =worst possible pain) from the baseline pain intensity scores (score range: 5 =moderate pain to 10 =worst possible pain; as participants with baseline pain score of at least moderate were included in study). Total possible score range for PID: -5 (worst score) to 10 (best score). (NCT01559259)
Timeframe: 0 to 2 hours, 0 to 6 hours, 0 to 8 hours, 0 to 12 hours post-dose
| Intervention | units on a scale (Mean) | |||
|---|---|---|---|---|
| 0 to 2 hours | 0 to 6 hours | 0 to 8 hours | 0 to12 hours | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 8.8 | 29.9 | 36.9 | 44.0 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 8.0 | 28.8 | 36.5 | 44.5 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 8.6 | 30.1 | 37.6 | 46.5 |
| Ibuprofen 400 mg | 7.2 | 26.8 | 34.2 | 43.7 |
| Placebo | 0.1 | 1.1 | 1.8 | 4.1 |
Pain intensity was assessed on a 4-point categorical pain severity rating scale. SPID4: Time-weighted sum of PID over post-dose time points. SPID4 score range was -2 (worst score) to 6 (best score) for SPID 0-2, -6 (worst score) to 18 (best score) for SPID 0-6, -8 (worst score) to 24 (best score) for SPID 0-8, -12 (worst score) to 36 (best score) for SPID 0-12. PID was calculated by subtracting the pain intensity score at given post-dose time points (pain severity score range: 0 [none] to 3 [severe]) from the baseline pain intensity scores (score range: 2 =moderate pain to 3 = severe pain; as participants with baseline pain score of at least moderate were included in study). Total possible score range for PID: -1 (worst score) to 3 (best score). (NCT01559259)
Timeframe: 0 to 2 hours, 0 to 6 hours, 0 to 8 hours, 0 to 12 hours post-dose
| Intervention | units on a scale (Mean) | |||
|---|---|---|---|---|
| 0 to 2 hours | 0 to 6 hours | 0 to 8 hours | 0 to 12 hours | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 2.7 | 9.1 | 11.2 | 13.3 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 2.4 | 8.5 | 10.7 | 12.9 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 2.7 | 9.3 | 11.6 | 14.1 |
| Ibuprofen 400 mg | 2.2 | 8.2 | 10.4 | 13.0 |
| Placebo | 0.1 | 0.7 | 1.0 | 2.0 |
TOTPAR: time-weighted sum of PRR scores over 2, 6, 8 and 12 hours. TOTPAR score range was 0 (worst score) to 8 (best score) for TOTPAR 0-2, 0 (worst score) to 24 (best score) for TOTPAR 0-6, 0 (worst score) to 32 (best score) for TOTPAR 0-8, 0 (worst score) to 48 (best score) for TOTPAR 0-12. PRR was assessed on a 5-point categorical pain relief rating scale where 0= No relief to 4= Complete relief. (NCT01559259)
Timeframe: 0 to 2 hours, 0 to 6 hours, 0 to 8 hours, 0 to 12 hours post-dose
| Intervention | units on a scale (Mean) | |||
|---|---|---|---|---|
| 0 to 2 hours | 0 to 6 hours | 0 to 8 hours | 0 to 12 hours | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 4.7 | 15.7 | 19.6 | 23.9 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 4.3 | 14.8 | 18.9 | 23.4 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 4.7 | 16.0 | 20.2 | 25.8 |
| Ibuprofen 400 mg | 4.0 | 14.3 | 18.4 | 23.9 |
| Placebo | 0.7 | 2.8 | 4.0 | 6.4 |
SPRID4: Time-weighted sum of PRR and PID based on 4 point categorical pain severity rating scale (PRID) with score range: -2(worst score) to 14 (best score) for SPRID 0-2, -6 (worst score) to 42 (best score) for SPRID 0-6 and -12 (worst score) to 84 (best score) for SPRID 0-12. PRID: sum of PID and PRR at post-dose time point with score range: -1 (worst score) to 7 (best score). PID calculated by subtracting pain intensity score at post-dose time points (score range: 0 [none] to 3 [severe]) from baseline pain intensity scores (score range: 2 =moderate pain to 3 = severe pain; as participants with baseline score of at least moderate were included). PID total possible score range: -1 (worst score) to 3(best score). PRR assessed on 5-point categorical scale with range: 0 =no relief to 4 =complete relief. (NCT01559259)
Timeframe: 0 to 2 hours, 0 to 6 hours, 0 to 12 hours post-dose
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| 0 to 2 hours | 0 to 6 hours | 0 to 12 hours | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 7.4 | 24.8 | 37.2 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 6.7 | 23.3 | 36.3 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 7.4 | 25.3 | 39.9 |
| Ibuprofen 400 mg | 6.2 | 22.5 | 36.9 |
| Placebo | 0.9 | 3.5 | 8.4 |
"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 1
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 2.8 |
| Control Group | 2.9 |
"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 2
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 2.5 |
| Control Group | 2.3 |
"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 3
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 1.9 |
| Control Group | 2.1 |
"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 4
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 1.5 |
| Control Group | 1.9 |
"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 5
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 1.7 |
| Control Group | 1.6 |
"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 6
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 1.5 |
| Control Group | 1.4 |
"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 7
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 1.3 |
| Control Group | 1.4 |
"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: BPI score will be collected at the preoperative visit
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 1.6 |
| Control Group | 1.0 |
"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score was collected for postoperative day 1
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 30.2 |
| Control Group | 29.4 |
"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 2
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 27.0 |
| Control Group | 23.5 |
"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 3
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 19.2 |
| Control Group | 22.5 |
"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 4
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 14.1 |
| Control Group | 16.8 |
"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 5
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 15.8 |
| Control Group | 15.0 |
"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 6
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 13.9 |
| Control Group | 11.7 |
"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 7
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 8.1 |
| Control Group | 10.1 |
"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for preoperative visit (the day before surgery)
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 12.4 |
| Control Group | 8.5 |
"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected at the preoperative visit
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 0 |
| Control Group | 0 |
"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 1
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 36.3 |
| Control Group | 38.9 |
"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 2
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 23.0 |
| Control Group | 21.6 |
"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 3
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 15.9 |
| Control Group | 12.9 |
"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 4
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 9.3 |
| Control Group | 11.8 |
"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 5
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 10.1 |
| Control Group | 7.8 |
"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 6
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 6.5 |
| Control Group | 6.6 |
"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 7
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 4.6 |
| Control Group | 5.4 |
Patients kept a daily medication log and reported the number of doses consumed per day (650mg acetaminophen, 600mg ibuprofen, 5mg oxycodone). The mean number of medication doses per day was calculated for each treatment group. (NCT03783702)
Timeframe: Postoperative day 1 to 7
| Intervention | Average number of medication doses/day (Mean) | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Oxycodone POD1 | Oxycodone POD2 | Oxycodone POD3 | Oxycodone POD4 | Oxycodone POD5 | Oxycodone POD6 | Oxycodone POD7 | Acetaminophen POD1 | Acetaminophen POD2 | Acetaminophen POD3 | Acetaminophen POD4 | Acetaminophen POD5 | Acetaminophen POD6 | Acetaminophen POD7 | Ibuprofen POD1 | Ibuprofen POD2 | Ibuprofen POD3 | Ibuprofen POD4 | Ibuprofen POD5 | Ibuprofen POD6 | Ibuprofen POD7 | |
| Control Group | 0.6 | 0.4 | 0.3 | 0.3 | 0.3 | 0.1 | 0 | 2.1 | 1.9 | 1.6 | 1.5 | 1.3 | 1.1 | 0.6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Experimental Group | 0.3 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0 | 2.0 | 1.8 | 1.3 | 1.0 | 0.9 | 0.9 | 0.6 | 0.6 | 0.5 | 0.4 | 0.3 | 0.4 | 0.3 | 0.2 |
Proportion of patients who receive new opioid discharge prescriptions at discharge following a thyroidectomy or parathyroidectomy procedure. This outcome excludes continuation of previous, chronic opioid therapy. (NCT04955444)
Timeframe: Up to 2 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Historical Control Group | 128 |
| Post-implementation Group | 28 |
Proportion of thyroidectomy and parathyroidectomy postoperative patients who receive new opioid prescriptions from the surgeon's office within 7 days of surgery including discharge prescriptions. This outcome excludes continuation of previous, chronic opioid therapy. (NCT04955444)
Timeframe: Up to 7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Historical Control Group | 0 |
| Post-implementation Group | 0 |
Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid discharge prescriptions exceeding the recommended dose of 112.5 oral MMEs (NCT04955444)
Timeframe: Up to 2 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Historical Control Group | 52 |
| Post-implementation Group | 8 |
Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid discharge prescriptions exceeding 5 days of therapy (NCT04955444)
Timeframe: Up to 2 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Historical Control Group | 27 |
| Post-implementation Group | 5 |
Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid prescriptions exceeding 50 oral MMEs/day when new, postoperative discharge prescriptions are added to existing opioid therapy (NCT04955444)
Timeframe: Up to 2 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Historical Control Group | 9 |
| Post-implementation Group | 0 |
"The time-adjusted Summed Pain Intensity Differences (SPIDs) of the VAS pain intensity scores up to 48 hours after the first dose of study medication.~This was calculated from the visual analogue scale (VAS) pain intensity scores recorded during the 48 hours double blind treatment period, with the last measure taken just prior to the final dose of blinded study medication. The visual analogue scale is 100mm long with 0= no pain and 100=worst pain imaginable. The Visual Analogue Scale It is expected that treatments which can provide superior analgesic effect will demonstrate a greater Summed Pain Intensity Difference." (NCT01420653)
Timeframe: 48 hours afte the first dose
| Intervention | score on a scale (Mean) |
|---|---|
| Maxigesic 325 | 31.56 |
| Acetaminophen | 17.71 |
| Ibuprofen | 23.18 |
| Placebo | 14.86 |
Postoperative hemorrhage is defined as any history of bleeding occurring within the 14 day postoperative period. Hemorrhage will be stratified into 3 levels of severity. Level 1: includes children with a history of postoperative bleeding evaluated and/or treated by a physician in the emergency room, inpatient unit or operating room; Level 2: children requiring inpatient admission for postoperative bleeding regardless of the need for operative intervention; Level 3: children requiring inpatient admission and return to the operating room for control of post-tonsillectomy hemorrhage. (NCT01605903)
Timeframe: Data about post-tonsillectomy bleeding will be obtained after the end of a 14-day postoperative period.
| Intervention | Participants (Count of Participants) |
|---|---|
| Treatment With Ibuprofen | 10 |
| Treatment With Acetaminophen | 4 |
The pain intensity difference was measured at rest over Days 1 through 3 in participants treated with etoricoxib (120 mg, 90 mg) compared to ibuprofen for the treatment of pain following total knee replacement orthopedic surgery. Pain intensity difference at rest was measured on a numerical rating scale (NRS) from 0 - 10 points (0=no pain, to 10=pain as bad as you can imagine). Comparison to ibuprofen was conducted in a step-down manner (the 90-mg dose was evaluated only if the null hypotheses for co-primary endpoints [Pain Intensity Difference (PID) and morphine] 120-mg doses were rejected). The primary analyses for change from baseline in average pain intensity at rest over Days 1 to 3 was performed using the longitudinal data analysis (LDA) method with the terms for baseline pain intensity (moderate or severe), type of anesthesia (spinal or general), treatment, day, and the interaction of day by treatment. (NCT00820027)
Timeframe: Baseline and Days 1-3
| Intervention | Score on a scale (Least Squares Mean) |
|---|---|
| Etoricoxib 90 mg | -3.93 |
| Etoricoxib 120 mg | -3.87 |
| Ibuprofen 1800 mg | -3.83 |
The pain intensity difference was measured at rest over Days 1 through 3 in patients treated with etoricoxib (120 mg, 90 mg) compared to placebo for the treatment of pain following total knee replacement orthopedic surgery. Pain intensity difference at rest was measured on a numerical rating scale (NRS) from 0 - 10 points (0=no pain, to 10=pain as bad as you can imagine). Comparison to placebo was conducted in a step-down manner (the 90-mg dose was evaluated only if the null hypotheses for co-primary endpoints [Pain Intensity Difference (PID) and Morphine] 120-mg doses were rejected). The primary analyses for change from baseline in average pain intensity at rest over Days 1 to 3 was performed using the longitudinal data analysis (LDA) method with the terms for baseline pain intensity (moderate or severe), type of anesthesia (spinal or general), treatment, day, and the interaction of day by treatment. (NCT00820027)
Timeframe: Baseline and Days 1-3
| Intervention | Score on a scale (Least Squares Mean) |
|---|---|
| Etoricoxib 90 mg | -3.93 |
| Etoricoxib 120 mg | -3.87 |
| Placebo | -3.39 |
The difference in average total daily dose of morphine used over Days 1 through 3 between participants treated with etoricoxib (120 mg, 90 mg) or ibuprofen 1800 mg (administered as 600 mg three times daily, every 8 hours) in the treatment of pain following total knee replacement orthopedic surgery was assessed. Opioids taken were converted to mg morphine equivalents according to the following conventions:1 mg morphine sulphate = 1 mg morphine, 1 mg morphine hydrochloride = 1.17 mg morphine. A 5 mg oxycodone tablet = 2.5 mg morphine,12.5 mg meperidine = 1.67 mg morphine. (NCT00820027)
Timeframe: Days 1-3
| Intervention | milligrams (mg) (Geometric Least Squares Mean) |
|---|---|
| Etoricoxib 90 mg | 8.87 |
| Etoricoxib 120 mg | 9.25 |
| Ibuprofen 1800 mg | 8.82 |
The average total dose of morphine was assessed when participant received etoricoxib 120 milligram(mg)/90 mg compared to placebo. Opioids taken were converted to mg morphine equivalents according to the following conventions: 1 mg morphine sulphate=1 mg morphine,1 mg morphine hydrochloride=1.17 mg morphine. A 5 mg oxycodone tablet=2.5 mg morphine,12.5 mg meperidine =1.67 mg morphine. Least-squares mean back-transformed; estimate obtained from longitudinal analysis of variance (ANOVA) model on log-transformed morphine dose with terms for baseline pain intensity(moderate or severe),type of anesthesia (spinal, general), treatment, day, and the interaction of day by treatment. (NCT00820027)
Timeframe: Days 1-3
| Intervention | milligrams (mg) (Geometric Least Squares Mean) |
|---|---|
| Etoricoxib 90 mg | 8.87 |
| Etoricoxib 120 mg | 9.25 |
| Placebo | 13.40 |
An AE is defined as any unfavorable and unintended change in the structure, function, or chemistry of the body temporally associated with the use of the study product, whether or not considered related to the use of the product. Any worsening (i.e., any clinically significant adverse change in frequency and/or intensity) of a preexisting condition which is temporally associated with the use of the study product, is also an AE. (NCT00820027)
Timeframe: Up to 7 days
| Intervention | Percentage of Participants (Number) |
|---|---|
| Etoricoxib 90 mg | 6.3 |
| Etoricoxib 120 mg | 3.5 |
| Ibuprofen 1800 mg | 4.5 |
| Placebo | 5.1 |
An adverse event (AE) is defined as any unfavorable and unintended change in the structure, function, or chemistry of the body temporally associated with the use of the study product, whether or not considered related to the use of the product. Any worsening (i.e., any clinically significant adverse change in frequency and/or intensity) of a preexisting condition which is temporally associated with the use of the study product, is also an AE. (NCT00820027)
Timeframe: Up to 21 days
| Intervention | Percentage of Participants (Number) |
|---|---|
| Etoricoxib 90 mg | 0.5 |
| Etoricoxib 120 mg | 0.0 |
| Ibuprofen 1800 mg | 0.0 |
| Placebo | 0.0 |
An AE is defined as any unfavorable and unintended change in the structure, function, or chemistry of the body temporally associated with the use of the study product, whether or not considered related to the use of the product. Any worsening (i.e., any clinically significant adverse change in frequency and/or intensity) of a preexisting condition which is temporally associated with the use of the study product, is also an AE. Edema is swelling caused by excess fluid trapped in body tissues. (NCT00820027)
Timeframe: Up to 21 days
| Intervention | Percentage of Participants (Number) |
|---|---|
| Etoricoxib 90 mg | 0.9 |
| Etoricoxib 120 mg | 1.7 |
| Ibuprofen 1800 mg | 1.8 |
| Placebo | 4.1 |
An AE is defined as any unfavorable and unintended change in the structure, function, or chemistry of the body temporally associated with the use of the study product, whether or not considered related to the use of the product. Any worsening (i.e., any clinically significant adverse change in frequency and/or intensity) of a preexisting condition which is temporally associated with the use of the study product, is also an AE. (NCT00820027)
Timeframe: Up to 21 days
| Intervention | Percentage of Participants (Number) |
|---|---|
| Etoricoxib 90 mg | 3.6 |
| Etoricoxib 120 mg | 1.3 |
| Ibuprofen 1800 mg | 3.1 |
| Placebo | 3.1 |
An AE is defined as any unfavorable and unintended change in the structure, function, or chemistry of the body temporally associated with the use of the study product, whether or not considered related to the use of the product. Any worsening (i.e., any clinically significant adverse change in frequency and/or intensity) of a preexisting condition which is temporally associated with the use of the study product, is also an AE. Opioid-related AEs include nausea, vomiting, constipation, somnolence, respiratory depression, urinary retention and ileus. (NCT00820027)
Timeframe: Up to 21 days
| Intervention | Percentage of Participants (Number) |
|---|---|
| Etoricoxib 90 mg | 34.7 |
| Etoricoxib 120 mg | 36.5 |
| Ibuprofen 1800 mg | 36.3 |
| Placebo | 41.8 |
Participant global evaluation of study medication was performed at the 8-hour time point or immediately before taking the rescue medication. It was scored on a 6-point categorical scale where 0 = Very poor, 1 = Poor, 2 = Fair, 3 = Good, 4 = Very Good, and 5 = Excellent. (NCT01098747)
Timeframe: 8 hours
| Intervention | Units on a scale (Mean) |
|---|---|
| Placebo | 1.1 |
| Ibuprofen Sodium | 3.8 |
| Ibuprofen (Advil + Motrin IB) | 3.7 |
Participants evaluated the time to first perceptible relief by stopping a stopwatch labeled 'first perceptible relief' at the moment they first began to experience any relief. Stopwatch was active up to 8 hours after dosing or until stopped by the participant, or rescue medication was administered. The first perceptible relief was considered confirmed if the participant also stopped the second stopwatch indicating meaningful relief. (NCT01098747)
Timeframe: 0 to 8 hours
| Intervention | Minutes (Median) |
|---|---|
| Placebo | NA |
| Ibuprofen Sodium | 16.4 |
| Ibuprofen (Advil + Motrin IB) | 25.7 |
Participants evaluated the time to meaningful relief by stopping a second stopwatch labeled 'meaningful relief' at the moment they first began to experience meaningful relief. Stopwatch was active up to 8 hours after dosing or until stopped by the participant, or rescue medication was administered. (NCT01098747)
Timeframe: 0 to 8 hours
| Intervention | Minutes (Median) |
|---|---|
| Placebo | NA |
| Ibuprofen Sodium | 42.4 |
| Ibuprofen (Advil + Motrin IB) | 55.3 |
Median time of dropping out of the participants from the study due to lack of efficacy or rescue medication, whichever came first. (NCT01098747)
Timeframe: 0 to 8 hours
| Intervention | Hours (Median) |
|---|---|
| Placebo | 1.7 |
| Ibuprofen Sodium | NA |
| Ibuprofen (Advil + Motrin IB) | NA |
SPRID: time-weighted sum of pain relief rating combined with pain intensity difference (PRID) over 8 hours. SPRID 0-8 score range: -8 (worst) to 56 (best). PRID: sum of Pain intensity differences (PID) and pain relief rating (PRR) at each time point. PRID score range: -1=worst to 7=best. PID: baseline pain severity score minus pain severity score at a given time point (pain severity score range 0=none to 3=severe; baseline score range 2=moderate to 3=severe). PID score range: -1(worst) to 3 (best). PRR: assessed on 5-point pain relief rating scale (0=No relief to 4=Complete relief). (NCT01098747)
Timeframe: 0 to 8 hours
| Intervention | Units on a scale (Mean) |
|---|---|
| Placebo | 5.4 |
| Ibuprofen Sodium | 29.8 |
Complete relief was defined as a PRR of 4. PRR was assessed on a 5-point categorical pain relief rating scale where 0=No relief to 4=Complete relief. (NCT01098747)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8 hours
| Intervention | Percentage of participants (Number) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hours | 0.5 hours | 1 hour | 1.5 hours | 2 hours | 3 hours | 4 hours | 5 hours | 6 hours | 7 hours | 8 hours | |
| Ibuprofen (Advil + Motrin IB) | 0.0 | 3.5 | 20.8 | 32.4 | 43.9 | 54.9 | 61.8 | 63.0 | 63.6 | 64.2 | 64.2 |
| Ibuprofen Sodium | 0.0 | 6.3 | 27.4 | 41.1 | 48.4 | 52.6 | 54.7 | 54.7 | 54.7 | 54.7 | 54.7 |
| Placebo | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 6.3 | 6.3 | 6.3 | 6.3 | 6.3 |
Percentage of participants with first perceptible relief was evaluated by stopping a stopwatch labeled 'first perceptible relief' at the moment the participant first began to experience any relief. Stopwatch was active up to 8 hours after dosing or until stopped by the participant, or rescue medication was administered. The first perceptible relief was considered confirmed if the participant also stopped the second stopwatch indicating meaningful relief. (NCT01098747)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8 hours
| Intervention | Percentage of participants (Number) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hours | 0.5 hours | 1 hour | 1.5 hours | 2 hours | 3 hours | 4 hours | 5 hours | 6 hours | 7 hours | 8 hours | |
| Ibuprofen (Advil + Motrin IB) | 12.1 | 60.7 | 84.4 | 87.3 | 87.9 | 88.4 | 88.4 | 88.4 | 88.4 | 88.4 | 88.4 |
| Ibuprofen Sodium | 26.3 | 84.2 | 94.7 | 95.8 | 95.8 | 95.8 | 95.8 | 95.8 | 95.8 | 95.8 | 95.8 |
| Placebo | 6.3 | 14.6 | 20.8 | 22.9 | 22.9 | 22.9 | 22.9 | 22.9 | 22.9 | 22.9 | 22.9 |
Percentage of participants with meaningful relief evaluated by stopping the stopwatch labeled 'meaningful relief' at the moment the participant first began to experience meaningful relief. Stopwatch was active up to 8 hours after dosing or until stopped by the participant, or rescue medication was administered. (NCT01098747)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8 hours
| Intervention | Percentage of participants (Number) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hours | 0.5 hours | 1 hour | 1.5 hours | 2 hours | 3 hours | 4 hours | 5 hours | 6 hours | 7 hours | 8 hours | |
| Ibuprofen (Advil + Motrin IB) | 0.6 | 16.8 | 52.6 | 69.9 | 79.8 | 86.7 | 87.9 | 87.9 | 87.9 | 87.9 | 88.4 |
| Ibuprofen Sodium | 1.1 | 28.4 | 73.7 | 87.4 | 91.6 | 94.7 | 94.7 | 94.7 | 94.7 | 95.8 | 95.8 |
| Placebo | 0.0 | 4.2 | 12.5 | 14.6 | 18.8 | 20.8 | 20.8 | 20.8 | 20.8 | 20.8 | 22.9 |
Percentage of participants who withdrew from the study due to lack of efficacy or received rescue medication. (NCT01098747)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8 hours
| Intervention | Percentage of participants (Number) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hours | 0.5 hours | 1 hour | 1.5 hours | 2 hours | 3 hours | 4 hours | 5 hours | 6 hours | 7 hours | 8 hours | |
| Ibuprofen (Advil + Motrin IB) | 0.0 | 0.0 | 0.0 | 2.3 | 5.8 | 8.1 | 8.1 | 10.4 | 12.1 | 16.2 | 20.2 |
| Ibuprofen Sodium | 0.0 | 0.0 | 0.0 | 1.1 | 2.1 | 4.2 | 9.5 | 10.5 | 13.7 | 20.0 | 26.3 |
| Placebo | 0.0 | 0.0 | 0.0 | 25.0 | 54.2 | 70.8 | 70.8 | 70.8 | 72.9 | 77.1 | 79.2 |
PID was derived by subtracting the pain severity score at a given post-dosing time point (pain severity score range 0 [none] to 3 [severe]) from the baseline score (Baseline pain severity score range 2 [moderate] to 3 [severe]). Total possible score range for PID: -1 (worst) to 3 (best). (NCT01098747)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8 hours
| Intervention | Units on a scale (Mean) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hours | 0.5 hours | 1 hour | 1.5 hour | 2 hours | 3 hours | 4 hours | 5 hours | 6 hours | 7 hours | 8 hours | |
| Ibuprofen (Advil + Motrin IB) | 0.1 | 0.6 | 1.3 | 1.5 | 1.7 | 1.7 | 1.7 | 1.6 | 1.5 | 1.2 | 1.1 |
| Ibuprofen Sodium | 0.3 | 1.0 | 1.5 | 1.7 | 1.8 | 1.6 | 1.5 | 1.4 | 1.2 | 0.9 | 0.8 |
| Placebo | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | -0.0 | -0.0 | -0.0 |
PRR was evaluated at different time points during the study up to 8 hours after taking the study medication, and immediately before rescue medication was taken (if necessary). PRR was assessed on a 5-point categorical pain relief rating scale where 0=No relief to 4=Complete relief. (NCT01098747)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8 hours
| Intervention | Units on a scale (Mean) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hours | 0.5 hours | 1 hour | 1.5 hours | 2 hours | 3 hours | 4 hours | 5 hours | 6 hours | 7 hours | 8 hours | |
| Ibuprofen (Advil + Motrin IB) | 0.5 | 1.5 | 2.5 | 2.8 | 3.0 | 3.0 | 3.0 | 2.8 | 2.6 | 2.3 | 2.2 |
| Ibuprofen Sodium | 0.7 | 2.0 | 2.9 | 3.1 | 3.1 | 2.9 | 2.8 | 2.6 | 2.3 | 1.9 | 1.7 |
| Placebo | 0.4 | 0.5 | 0.6 | 0.7 | 0.7 | 0.7 | 0.8 | 0.7 | 0.7 | 0.5 | 0.5 |
PRID was sum of PID and PRR at each post-dosing time point. The overall possible score range, for PRID was -1 (worst) to 7 (best). PID was derived by subtracting the pain severity score at a given post-dosing time point (pain severity score range 0 [none] to 3 [severe]) from the baseline score (Baseline pain severity score range 2 [moderate] to 3 [severe]). Total possible score range for PID: -1 (worst) to 3 (best). PRR was assessed on 5-point categorical pain relief rating scale (0=No relief to 4=Complete relief). (NCT01098747)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8 hours
| Intervention | Units on a scale (Mean) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hours | 0.5 hours | 1 hour | 1.5 hours | 2 hours | 3 hours | 4 hours | 5 hours | 6 hours | 7 hours | 8 hours | |
| Ibuprofen (Advil + Motrin IB) | 0.6 | 2.1 | 3.8 | 4.3 | 4.7 | 4.7 | 4.8 | 4.4 | 4.1 | 3.5 | 3.2 |
| Ibuprofen Sodium | 1.1 | 3.0 | 4.4 | 4.8 | 4.9 | 4.5 | 4.3 | 4.0 | 3.5 | 2.9 | 2.6 |
| Placebo | 0.4 | 0.6 | 0.7 | 0.7 | 0.8 | 0.7 | 0.9 | 0.8 | 0.6 | 0.5 | 0.5 |
SPID: time-weighted sum of PID over 2, 3, 6 and 8 hours. SPID scores range was -2 (worst) to 6 (best) for SPID 0-2, -3 (worst) to 9 (best) for SPID 0-3, -6 (worst) to 18 (best) for SPID 0-6, -8 (worst) to 24 (best) for SPID 0-8. PID: baseline pain severity score minus pain severity score at a given time point (pain severity score range 0=none to 3=severe; baseline score range 2=moderate to 3=severe). Total score range for PID: -1(worst) to 3 (best). (NCT01098747)
Timeframe: 0-2, 0-3, 0-6, 0-8 hours
| Intervention | Units on a scale (Mean) | |||
|---|---|---|---|---|
| SPID 0-2 | SPID 0-3 | SPID 0-6 | SPID 0-8 | |
| Ibuprofen (Advil + Motrin IB) | 2.4 | 4.1 | 8.9 | 11.1 |
| Ibuprofen Sodium | 2.8 | 4.4 | 8.5 | 10.2 |
| Placebo | 0.1 | 0.1 | 0.2 | 0.1 |
TOTPAR: time-weighted sum of PRR scores over 2, 3, 6 and 8 hours. TOTPAR score range was 0 (worst) to 8 (best) for TOTPAR 0-2, 0 (worst) to 12 (best) for TOTPAR 0-3, 0 (worst) to 24 (best) for TOTPAR 0-6, 0 (worst) to 32 (best) for TOTPAR 0-8. PRR was evaluated at different time points during the study up to 8 hours, and immediately after taking rescue medication (if necessary). PRR was assessed on a 5-point categorical pain relief rating scale wherein 0=No relief to 4=Complete relief. (NCT01098747)
Timeframe: 0-2, 0-3, 0-6, 0-8 hours
| Intervention | Units on a scale (Mean) | |||
|---|---|---|---|---|
| TOTPAR 0-2 | TOTPAR 0-3 | TOTPAR 0-6 | TOTPAR 0-8 | |
| Ibuprofen (Advil + Motrin IB) | 4.6 | 7.6 | 16.1 | 20.6 |
| Ibuprofen Sodium | 5.2 | 8.1 | 15.9 | 19.5 |
| Placebo | 1.3 | 2.0 | 4.2 | 5.2 |
SPRID: time-weighted sum of PRID over 2, 3, 6 and 8 hours. SPRID score range:-2 (worst) to 14(best) for SPRID 0-2, -3(worst) to 21(best) for SPRID 0-3, -6(worst) to 42(best) for SPRID 0-6, -8(worst) to 56(best) for SPRID 0-8. PRID:sum of PID and PRR at each time point. Total score range for PRID: -1=worst to 7=best. PID:baseline pain severity score minus pain severity score at given time(score range 0=none to 3=severe; baseline score range 2=moderate to 3=severe). Total score range for PID: -1(worst) to 3(best), PRR: scored on 5-point pain relief rating scale(0=No relief to 4=Complete relief). (NCT01098747)
Timeframe: 0-2, 0-3, 0-6, 0-8 hours
| Intervention | Units on a scale (Mean) | |||
|---|---|---|---|---|
| SPRID 0-2 | SPRID 0-3 | SPRID 0-6 | SPRID 0-8 | |
| Ibuprofen (Advil + Motrin IB) | 7.0 | 11.8 | 25.0 | 31.7 |
| Ibuprofen Sodium | 8.0 | 12.6 | 24.3 | 29.8 |
| Placebo | 1.3 | 2.1 | 4.4 | 5.4 |
"Visual Analog Scale (VAS) assessments following surgery. The VAS is a continuous scale compromised of a horizontal line, one hundred millimeters in length, anchored by 2 verbal descriptors (No Pain, Worst Possible Pain). The VAS is self-completed by the respondent. The respondent is asked to place a line perpendicular to the VAS line at the point that represents their pain intensity. Using a ruler, the score is determined by measuring the distance, in mm, on the 100 mm line between the No Pain anchor and the subject's mark. The score would be between o and 100." (NCT01334957)
Timeframe: 6 hours
| Intervention | units on a scale (Mean) |
|---|---|
| Intravenous Ibuprofen | 30.9 |
The incidence of treatment-emergent adverse events occurring in the six hours following administration of the last dose of intravenous ibuprofen (NCT01334957)
Timeframe: 6 hours
| Intervention | Number of Adverse Events (Number) |
|---|---|
| Intravenous Ibuprofen | 16 |
The incidence of treatment-emergent serious adverse events occurring in the six hours following administration of the last dose of intravenous ibuprofen (NCT01334957)
Timeframe: 6 hours
| Intervention | Number of Serious Adverse Events (Number) |
|---|---|
| Intravenous Ibuprofen | 0 |
The incidence of treatment-emergent adverse events occurring in the six hours following administration of the first dose of intravenous ibuprofen (NCT01334957)
Timeframe: 6 hours
| Intervention | Number of Adverse Events (Number) |
|---|---|
| Intravenous Ibuprofen | 49 |
The incidence of treatment-emergent serious adverse events occurring in the six hours following administration of the first dose of intravenous ibuprofen (NCT01334957)
Timeframe: 6 hours
| Intervention | Number of Serious Adverse Events (Number) |
|---|---|
| Intravenous Ibuprofen | 8 |
Number of non-opioid group members switching to receiving opioid medication - assessed via the take-home pain diary. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Non-opioid Pain Control | 7 |
Number of participants with emergency department or urgent care visits in 14 post-operative days - assessed via the electronic medical record and the take-home pain diary. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Opioid Pain Control | 8 |
| Non-opioid Pain Control | 11 |
Number of participants with hospitalizations after discharge in 14 days - assessed using the electronic medical record and the take-home pain diary. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Opioid Pain Control | 3 |
| Non-opioid Pain Control | 8 |
"Score assigned by the patient at the end of 14 post-operative days in the take-home pain diary using a Likert scale. Patients will respond to the following statement I am happy with the pain relief I received in the last 14 days with responses ranging from strongly agree to strongly disagree. The responses will be assigned a numerical value, from 0 (strongly disagree) to 4 (strongly agree), and the average value for all subjects in the group will be reported as the overall pain relief satisfaction. Higher scores mean a better outcome." (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | score on a scale (Mean) |
|---|---|
| Opioid Pain Control | 3.35 |
| Non-opioid Pain Control | 3.09 |
Number of post-operative phone calls to nursing staff, obtained using the electronic medical record. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | post-operative phone calls (Mean) |
|---|---|
| Opioid Pain Control | 0.35 |
| Non-opioid Pain Control | 0.47 |
In the take-home pain diary, patients will record the amount of medication taken for each dose. The mean value of these doses will be calculated and averaged within each group to determine the average dose of each analgesic used. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Milliliters (Mean) | ||
|---|---|---|---|
| Acetaminophen | Ibuprofen | Oxycodone | |
| Non-opioid Pain Control | 7.52 | 7.53 | 0.04 |
| Opioid Pain Control | 6.54 | 7.53 | 0.13 |
Average pain over 14 post-operative days before and after medications. This is quantified using the validated Wong-Baker FACES pain metric. Patients receive a take-home pain diary and for 14 days report their maximum pain both before and after taking pain medication. The mean of these pain ratings will be the primary outcome measure. The Wong-Baker FACES scale is from 0 (min) to 10 (max). A higher score indicates worse outcome/pain. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Score on a scale (Mean) | |
|---|---|---|
| Before | After | |
| Non-opioid Pain Control Group | 5.66 | 2.24 |
| Opioid Pain Control Group | 5.78 | 2.33 |
Using the results of the take-home pain diary, we will calculate the average number of days of use of each analgesic for each group. The last day after which there is no subsequent use of analgesic will define the end-point of the duration of use. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | days (Mean) | ||
|---|---|---|---|
| Acetaminophen | Ibuprofen | Oxycodone | |
| Non-opioid Pain Control | 8.64 | 8.75 | 0.45 |
| Opioid Pain Control | 8.61 | 8.49 | 2.62 |
Using the take-home pain diary, the total amount in mL of each analgesic used over 14 days by each patient in a group will be averaged and reported. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Milliliters (Mean) | ||
|---|---|---|---|
| Acetaminophen | Ibuprofen | Oxycodone | |
| Non-opioid Pain Control | 326.98 | 334.65 | 2.96 |
| Opioid Pain Control | 292.48 | 324.14 | 6.47 |
Rescue narcotic in both groups will be recorded and compared using a standard equianalgesic oral morphine equivalent (OME) calculation (NCT02351700)
Timeframe: until discharge from hospital, an expected stay of 2 days
| Intervention | mg (Mean) |
|---|---|
| Opioid-sparing Group | 26.3 |
| Standard Treatment Group | 62.5 |
Comparison of pain scores between two arms using Visual Analog Scale (VAS) for Pain. Units of measure are 0=No Pain, 1=Annoying, 2=Mild Pain, 3=Troublesome, 4=Nagging Pain, Uncomfortable, 5=Distressing, 6=Miserable, 7=Horrible, 8=Intense, Dreadful, 9=Unbearable, 10=Worst Possible Pain. Higher values represent a worse outcome. There are no subscales. (NCT02351700)
Timeframe: mean pain score over 48 hours
| Intervention | 0-10 units on a scale (Mean) |
|---|---|
| Opioid-sparing Group | 1.7 |
| Standard Treatment Group | 2.8 |
Length of hospital stay from time of surgery to time of discharge. (NCT02351700)
Timeframe: until discharge from hospital, an expected stay of 2 days
| Intervention | hours (Mean) |
|---|---|
| Opioid-sparing Group | 71.3 |
| Standard Treatment Group | 51.7 |
Epistaxis, potentially related to IV ibuprofen, will be compared between two groups (NCT02351700)
Timeframe: until discharge from hospital, an expected stay of 2 days
| Intervention | participants (Number) |
|---|---|
| Opioid Sparing Group | 0 |
| Standard Treatment Group | 2 |
patients with one or more bowel movement(s) in the first 48 hours after surgery (NCT02351700)
Timeframe: until discharge from hospital, an expected stay of 2 days
| Intervention | participants (Number) |
|---|---|
| Opioid-sparing Group | 9 |
| Standard Treatment Group | 12 |
Use of antiemetics in first 48 hours after surgery (NCT02351700)
Timeframe: until discharge from hospital, an expected stay of 2 days
| Intervention | dose (Mean) |
|---|---|
| Opioid-sparing Group | 9.8 |
| Standard Treatment Group | 10.1 |
Pain is measured on a visual analog scale 0=no pain and 10=worst pain imaginable. (NCT02268955)
Timeframe: 120 minutes post medication administration
| Intervention | score on a scale (Median) |
|---|---|
| Control Group: Adults Age 18-55 Years | 3.0 |
| IV Ibuprofen: Adults Age 18-55 Years | 0.3 |
Change in the amount of morphine use (in milligrams) by subjects in each treatment group for a 24 hour period post-surgery (NCT00225732)
Timeframe: 24 Hours
| Intervention | milligrams (Least Squares Mean) |
|---|---|
| Placebo | 57.0 |
| 800 mg Intravenous Ibuprofen | 48.7 |
"Subjects asked to fill out a patient diary recording their pain intensity level (on 100mm Visual Analog Scale) prior to taking study medication every 4 hours.~The daily average pain intensity levels are reported as a score on a scale of 0-100, with higher score meaning worse outcome.~The daily average pain levels were assessed daily for 1 week post-operatively, then compared between the 2 groups using a two-group Student's t-test." (NCT02029235)
Timeframe: 1 week post-operatively
| Intervention | score on a scale (0-100, higher = worse) (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Daily average pain intensity level on PostOp Day 1 | Daily average pain intensity level on PostOp Day 2 | Daily average pain intensity level on PostOp Day 3 | Daily average pain intensity levelon PostOp Day 4 | Daily average pain intensity level on PostOp Day 5 | Daily average pain intensity level on PostOp Day 6 | Daily average pain intensity level on PostOp Day 7 | |
| Acetaminophen/Hydrocodone (AH) Group | 24.07 | 30.16 | 22.11 | 18.53 | 16.61 | 13.58 | 13.00 |
| Acetaminophen/Ibuprofen (AIBU) Group | 22.17 | 22.22 | 15.67 | 13.17 | 14.03 | 13.44 | 12.67 |
"Subjects asked to fill out a patient diary recording their pain relief (on a Likert scale) one hour after taking study medication every 4 hours.~Daily average pain relief scores are reported as a score on a scale of 0-3, with higher score meaning better outcome.~The daily average pain relief scores were assessed daily for 1 week post-operatively, then compared using generalized linear mixed-effects models" (NCT02029235)
Timeframe: 1 week postoperatively
| Intervention | score on a scale (0-3, higher = better) (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Daily average pain relief on PostOp Day 1 | Daily average pain relief on PostOp Day 2 | Daily average pain relief on PostOp Day 3 | Daily average pain relief on PostOp Day 4 | Daily average pain relief on PostOp Day 5 | Daily average pain relief on PostOp Day 6 | Daily average pain relief on PostOp Day 7 | |
| Acetaminophen/Hydrocodone (AH) Group | 1.53 | 1.76 | 2.33 | 2.46 | 2.54 | 2.84 | 2.88 |
| Acetaminophen/Ibuprofen (AIBU) Group | 1.84 | 2.27 | 2.63 | 2.91 | 2.88 | 2.87 | 2.96 |
"pain measurement as assessed on a visual analog scale and pain medication usage~definition of success = no or mild pain as analyzed on VAS scale and no narcotic use; analyzed by logistic regression~VAS scale is 0 to 170 mm with the higher numbers indicating more pain and less success." (NCT01870973)
Timeframe: each day for 5 days
| Intervention | percentage of participants (Number) |
|---|---|
| Root Canal Treatment | 52 |
| no Root Canal Treatment | 43 |
Measure effectiveness of placebo as an adjunct to ibuprofen and paracervical block for pain control during uterine aspiration by comparing the maximum pain score; as measured by VAS between women randomized to receive placebo adhesives and routine care controls - using a 100 mm visual analog scale (VAS-P) (anchors: 0 mm = no pain, 100 mm = worst pain in my life). (NCT03391986)
Timeframe: prior to the procedure (baseline), at the completion of the procedure (approximately 10 minutes later)
| Intervention | score on a scale (Mean) |
|---|---|
| Placebo Adhesives | 70.0 |
| Routine Care | 71.0 |
Using a satisfaction survey (investigator-developed, 6 questions, each question is graded on a scale of 1-5, 1 being very poor and 5 being very good) to measure effectiveness of auricular acupuncture for improving satisfaction. (NCT03391986)
Timeframe: at the completion of the procedure (approximately 5-10 minutes)
| Intervention | percentage of participants (Number) |
|---|---|
| Pyonex Needles | 94 |
| Routine Care | 76 |
Measure effectiveness of auricular acupuncture as an adjunct to ibuprofen and paracervical block for pain control during first trimester uterine aspiration by comparing the maximum pain score; as measured by VAS between women randomized to receive auricular acupuncture and routine care controls - using a 100 mm visual analog scale (VAS-P) (anchors: 0 mm = no pain, 100 mm = worst pain in my life). The VAS has no sub-scales. (NCT03391986)
Timeframe: at the completion of the procedure (approximately 10 minutes later)
| Intervention | score on a scale (Mean) |
|---|---|
| Pyonex Needles | 39.5 |
| Routine Care | 71.0 |
Discharge readiness is the number of hours until meeting the following 4 criteria: (1) adequate analgesia (defined as pain less than 4 on a NRS of 0-10); (2) independence from intravenous analgesics; (3) ability to ambulate 30 m and (4) ability to stand, walk 3 m, and return to a sitting position without another's assistance. (NCT01759277)
Timeframe: 7 postoperative days
| Intervention | hours (Median) |
|---|---|
| Control | 61 |
| Experimental | 55 |
The time in hours until adequate analgesia is defined as pain less than 4 on a Numeric Rating Scale of 0-10, with 0=no pain and 10=worst imaginable pain (NCT01759277)
Timeframe: First 7 postoperative days
| Intervention | Hours (Mean) |
|---|---|
| Control | 61.6 |
| Experimental | 61.0 |
The time in hours until a patient could ambulate at least 30 meters independently (regardless of time to achieve the 30 meters) (NCT01759277)
Timeframe: 7 postoperative days
| Intervention | Hours (Mean) |
|---|---|
| Control | 40.9 |
| Experimental | 56.6 |
The time in hours until no intravenous analgesics were required for at least 12 hours (without future intravenous use during admission) (NCT01759277)
Timeframe: First 7 postoperative days
| Intervention | Hours (Mean) |
|---|---|
| Control | 46.1 |
| Experimental | 47.5 |
The timed-up-and-go (TUG) test measures the ability and speed of standing from a sitting position, walking 3 meters and returning to the original seated position independent from the assistance of healthcare personnel. This variable measured the time in hours until the patient could successfully achieve this test independently, regardless of the amount of time required. (NCT01759277)
Timeframe: Hours
| Intervention | Hours (Mean) |
|---|---|
| Control | 33.4 |
| Experimental | 46.8 |
Amount of opioid consumed as measured with intravenous morphine equivalents in milligrams (NCT01759277)
Timeframe: Postoperative Days 0-3
| Intervention | milligrams (Mean) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Recovery Room | Postoperative Day 0 (day) | Postoperative Day 0 (evening) | Postoperative Day 1 (night) | Postoperative Day 1 (Day) | Postoperative Day 1 (evening) | Postoperative Day 2 (night) | Postoperative Day 2 (day) | Postoperative Day 2 (evening) | Postoperative Day 3 (night | |
| Control | 8.6 | 0.9 | 7.2 | 5.1 | 11.0 | 8.6 | 4.1 | 9.6 | 6.5 | 4.9 |
| Experimental | 8.0 | 1.5 | 8.5 | 5.6 | 12.6 | 10.9 | 5.6 | 10.2 | 7.2 | 5.1 |
The amount of pain evaluated using the 0-10 Numeric Rating Scale with 0=no pain and 10=worst imaginable pain (NCT01759277)
Timeframe: Postoperative Days 1-3
| Intervention | score on a scale (Mean) | ||
|---|---|---|---|
| Postoperative Day 1 (08:00-16:00) | Postoperative Day 2 (08:00-16:00) | Postoperative Day 3 (00:00-8:00) | |
| Control | 4.4 | 3.7 | 2.5 |
| Experimental | 3.7 | 3.4 | 2.8 |
The distribution of cutaneous sensation affected by the different techniques of adductor canal blockade is assessed using a monofilament Neuropen to prick points on a 20 point grid applied to the skin in a standard fashion according to this method: A grid will be marked starting with anatomical landmarks at the knee joint: the medial inter-knee-joint point where the tibia meets the femur, the mid medial patella, the mid lateral patella, and along the same line at the semitendinosus tendon and 5cm posterior from that point. Then 5cm intervals will be plotted progressing cephalad to a total of 15 centimeters. This will yield 20 grid points (5x4 points). Once the grid is made, testing proceeds with a Neuropen on a scale of 0-1, with 1 = normal sharp sensation, 0 = change of sensation. The Neuropen is used for the standardization of force. (NCT02788019)
Timeframe: 20 minutes
| Intervention | points of cutaneous sensation (Mean) |
|---|---|
| Mid-Thigh Adductor Block | 19.81 |
| Distal-Thigh Adductor Block | 20 |
Measuring the quadriceps muscle strength (surgical side) using a dynamometer.Patients were placed supine with a cushion underneath their knee, resulting in a 45-degree angle at the knee. A dynamometer was placed on the anterior of the ankle, between the malleoli. Patients were instructed to extend their legs three times each, with a 30-s pause between each attempt (Lafayette Manual Muscle Test System; Lafayette Instrument Company, Lafayette, IN; and all three dynamometer readings in Kgf unit for each leg were recorded.Kgf is a gravitational metric unit force ,it is equal to the magnitude of the force exerted on one kilogram of mass under standard gravity. (NCT03053401)
Timeframe: 4 hours following peripheral nerve block performance
| Intervention | Kilogram-force (Kgf) (Median) |
|---|---|
| Adductor Canal Block | 1.1 |
| Femoral Nerve Block | 0.0 |
Total intravenous morphine/morphine equivalent consumption in milligrams (mg) at 24 hours post-block (NCT03053401)
Timeframe: 24 hours following peripheral nerve block performance.
| Intervention | milligrams (Mean) |
|---|---|
| Adductor Canal Block | 28.9 |
| Femoral Nerve Block | 26.9 |
Assessed by Numeric Scale (NS) pain scoring system. Minimum 0 and maximum 10 . Higher scores means worse outcome (pain) (NCT03053401)
Timeframe: 4 hours and 24 hours
| Intervention | score on a scale (Median) | |
|---|---|---|
| 4 hours post block | 24 hours post block | |
| Adductor Canal Block | 4.5 | 5.0 |
| Femoral Nerve Block | 4.5 | 6.0 |
(NCT02121392)
Timeframe: within first 3 days (plus or minus 3 days) after surgery
| Intervention | Days (Mean) |
|---|---|
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 2.42 |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 2.67 |
(NCT02121392)
Timeframe: within first 3 days (plus or minus 3 days) after surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 0 |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 0 |
(NCT02121392)
Timeframe: within first 3 days (plus or minus 3 days) after surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 0 |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 0 |
(NCT02121392)
Timeframe: 12 hours postoperatively and 20 hours after placement of catheter
| Intervention | milligrams of morphine (Mean) | |
|---|---|---|
| 12 hours postoperatively | 20 hours after placement of catheter | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 12.5 | 73.9 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 11.9 | 96.5 |
(NCT02121392)
Timeframe: Daily on postoperative days one and two
| Intervention | meters (Mean) | |
|---|---|---|
| Postoperative Day 1 | Postoperative Day 2 | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 17.6 | 39.4 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 13.8 | 32.5 |
Knee range of motion (ROM) was measured (in degrees) during physical therapy. (NCT02121392)
Timeframe: postoperative day 1 and 2
| Intervention | degrees (Mean) | |
|---|---|---|
| Postoperative Day 1 | Postoperative Day 2 | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 40.6 | 62.5 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 51.4 | 71.3 |
(NCT02121392)
Timeframe: 3 and 6 weeks
| Intervention | degrees (Mean) | |
|---|---|---|
| 3 weeks | 6 weeks | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 94.3 | 105 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 98.2 | 109 |
"The visual analog scale (VAS) is a pain rating scale. Scores are based on self-reported measures of symptoms that are recorded with a single mark placed at one point along the length of a line that represents a continuum between the two ends of the scale-no pain on the left end of the scale (equal to a score of 0) and the worst pain on the right end of the scale (equal to a score of 100)." (NCT02121392)
Timeframe: 12 hours postoperatively and 20 hours after placement of catheter
| Intervention | mm (Mean) | |
|---|---|---|
| 12 hours postoperatively | 20 hours after placement of catheter | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 26.9 | 28.6 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 27.9 | 36.4 |
The Western Ontario and McMaster Universities Arthritis Index (WOMAC) is widely used in the evaluation of Hip and Knee Osteoarthritis. It is a self administered questionnaire consisting of 24 items divided into 3 subscales: pain (5 items), stiffness (2 items), and physical function (17 items). The subscale scores can vary, with pain ranging from 0 to 20 points; stiffness, 0 to 8 points; and physical function, 0 to 68 points. Higher scores represent worse pain, stiffness, and functional limitations. A sum of the scores for all three subscales yields a total WOMAC score. (NCT02121392)
Timeframe: 3 and 6 weeks
| Intervention | score on a scale (Mean) | |
|---|---|---|
| 3 weeks | 6 weeks | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 29.1 | 27.9 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 37.8 | 32.9 |
(NCT03007966)
Timeframe: 24 hrs Post Nerve Block
| Intervention | Participants (Count of Participants) |
|---|---|
| Ilioinguinal / Iliohypogastric Block | 2 |
| Quadratus Lumborum Block | 3 |
(NCT03007966)
Timeframe: 8 hrs Post Nerve Block
| Intervention | Participants (Count of Participants) |
|---|---|
| Ilioinguinal / Iliohypogastric Block | 0 |
| Quadratus Lumborum Block | 4 |
(NCT03007966)
Timeframe: 24 hrs Post Nerve Block
| Intervention | Participants (Count of Participants) |
|---|---|
| Ilioinguinal / Iliohypogastric Block | 6 |
| Quadratus Lumborum Block | 3 |
(NCT03007966)
Timeframe: 8 hrs Post Nerve Block
| Intervention | Participants (Count of Participants) |
|---|---|
| Ilioinguinal / Iliohypogastric Block | 9 |
| Quadratus Lumborum Block | 5 |
(NCT03007966)
Timeframe: 24 hrs Post Nerve Block
| Intervention | Participants (Count of Participants) |
|---|---|
| Ilioinguinal / Iliohypogastric Block | 3 |
| Quadratus Lumborum Block | 2 |
(NCT03007966)
Timeframe: 8 hrs Post Nerve Block
| Intervention | Participants (Count of Participants) |
|---|---|
| Ilioinguinal / Iliohypogastric Block | 3 |
| Quadratus Lumborum Block | 3 |
Assessed on an 11 point (0-10) numeric analog scale with a higher score denoting a worse outcome (NCT03007966)
Timeframe: 24 hrs Post Nerve Block
| Intervention | score on a scale (Mean) |
|---|---|
| Ilioinguinal / Iliohypogastric Block | 3 |
| Quadratus Lumborum Block | 2.7 |
Assessed on an 11-point (0-10) numeric analog scale with a higher score denoting a worse outcome (NCT03007966)
Timeframe: 8 hrs Post Nerve Block
| Intervention | score on a scale (Mean) |
|---|---|
| Ilioinguinal / Iliohypogastric Block | 3.6 |
| Quadratus Lumborum Block | 3.3 |
Assessed on an 11 point (0-10) numeric analog scale with a higher score denoting a worse outcome (NCT03007966)
Timeframe: 24hrs Post Nerve Block
| Intervention | score on a scale (Mean) |
|---|---|
| Ilioinguinal / Iliohypogastric Block | 4.9 |
| Quadratus Lumborum Block | 5.3 |
Assessed on an 11-point (0-10) numeric analog scale with a higher score denoting a worse outcome. (NCT03007966)
Timeframe: 8 hrs Post Nerve Block
| Intervention | score on a scale (Mean) |
|---|---|
| Ilioinguinal / Iliohypogastric Block | 5.10 |
| Quadratus Lumborum Block | 5.03 |
When does the patient require their first post operative analgesic dose? (NCT03007966)
Timeframe: 24hrs Post Nerve Block
| Intervention | minutes (Median) |
|---|---|
| Ilioinguinal / Iliohypogastric Block | 141 |
| Quadratus Lumborum Block | 91 |
Total opioids consumed during the first 24hrs post operatively. Measured as 24hr Oxycodone Equivalent (NCT03007966)
Timeframe: 24 hrs Post Nerve Block
| Intervention | milligrams (Mean) |
|---|---|
| Ilioinguinal / Iliohypogastric Block | 19.7 |
| Quadratus Lumborum Block | 25.2 |
"To determine whether treatment with the Gentlewave system will significantly change the level of post-operative pain following endodontic treatment as measured by the VAS scale.~Pain measurements were made using a 0-100 VAS- NRS. The '0' mark represented 'no pain' and the '100' mark represented 'the worst pain imaginable'. Scores 0-19 represented low pain, 20-39 was mild pain, 40-59 was moderate pain, 60-79 was high pain, and 80-100 was very high or severe pain. For this study, scores in the very high range were considered severe pain." (NCT03635515)
Timeframe: 168 hours
| Intervention | score on VAS scale (Mean) |
|---|---|
| Standard Protocol (Control) Group | 5.22 |
| Gentlewave Treatment Group | 2.78 |
"To determine whether treatment with the Gentlewave system will significantly change the level of post-operative pain following endodontic treatment as measured by the VAS scale.~Pain measurements were made using a 0-100 VAS- NRS. The '0' mark represented 'no pain' and the '100' mark represented 'the worst pain imaginable'. Scores 0-19 represented low pain, 20-39 was mild pain, 40-59 was moderate pain, 60-79 was high pain, and 80-100 was very high or severe pain. For this study, scores in the very high range were considered severe pain." (NCT03635515)
Timeframe: 24 hours
| Intervention | score on VAS scale (Mean) |
|---|---|
| Standard Protocol (Control) Group | 19.33 |
| Gentlewave Treatment Group | 7.78 |
"To determine whether treatment with the Gentlewave system will significantly change the level of post-operative pain following endodontic treatment as measured by the VAS scale.~Pain measurements were made using a 0-100 VAS- NRS. The '0' mark represented 'no pain' and the '100' mark represented 'the worst pain imaginable'. Scores 0-19 represented low pain, 20-39 was mild pain, 40-59 was moderate pain, 60-79 was high pain, and 80-100 was very high or severe pain. For this study, scores in the very high range were considered severe pain." (NCT03635515)
Timeframe: 6 hours
| Intervention | score on VAS scale (Mean) |
|---|---|
| Standard Protocol (Control) Group | 23.2 |
| Gentlewave Treatment Group | 11.56 |
"To determine whether treatment with the Gentlewave system will significantly change the level of post-operative pain following endodontic treatment as measured by the VAS scale.~Pain measurements were made using a 0-100 VAS- NRS. The '0' mark represented 'no pain' and the '100' mark represented 'the worst pain imaginable'. Scores 0-19 represented low pain, 20-39 was mild pain, 40-59 was moderate pain, 60-79 was high pain, and 80-100 was very high or severe pain. For this study, scores in the very high range were considered severe pain." (NCT03635515)
Timeframe: 72 hours
| Intervention | score on VAS scale (Mean) |
|---|---|
| Standard Protocol (Control) Group | 13.11 |
| Gentlewave Treatment Group | 5 |
"To determine whether treatment with the Gentlewave system will significantly change the level of post-operative pain following endodontic treatment as measured by the VAS scale.~Pain measurements were made using a 0-100 VAS- NRS. The '0' mark represented 'no pain' and the '100' mark represented 'the worst pain imaginable'. Scores 0-19 represented low pain, 20-39 was mild pain, 40-59 was moderate pain, 60-79 was high pain, and 80-100 was very high or severe pain. For this study, scores in the very high range were considered severe pain." (NCT03635515)
Timeframe: 168 hours
| Intervention | score on VAS scale (Mean) |
|---|---|
| Standard Protocol (Control) Group | 8 |
| Gentlewave Treatment Group | 6 |
"To determine whether treatment with the Gentlewave system will significantly change the level of post-operative pain following endodontic treatment as measured by the VAS scale.~Pain measurements were made using a 0-100 VAS- NRS. The '0' mark represented 'no pain' and the '100' mark represented 'the worst pain imaginable'. Scores 0-19 represented low pain, 20-39 was mild pain, 40-59 was moderate pain, 60-79 was high pain, and 80-100 was very high or severe pain. For this study, scores in the very high range were considered severe pain." (NCT03635515)
Timeframe: 24 hours
| Intervention | score on VAS scale (Mean) |
|---|---|
| Standard Protocol (Control) Group | 25 |
| Gentlewave Treatment Group | 21 |
"To determine whether treatment with the Gentlewave system will significantly change the level of post-operative pain following endodontic treatment as measured by the VAS scale.~Pain measurements were made using a 0-100 VAS- NRS. The '0' mark represented 'no pain' and the '100' mark represented 'the worst pain imaginable'. Scores 0-19 represented low pain, 20-39 was mild pain, 40-59 was moderate pain, 60-79 was high pain, and 80-100 was very high or severe pain. For this study, scores in the very high range were considered severe pain." (NCT03635515)
Timeframe: 6 hours
| Intervention | score on VAS scale (Mean) |
|---|---|
| Standard Protocol (Control) Group | 22 |
| Gentlewave Treatment Group | 24 |
"To determine whether treatment with the Gentlewave system will significantly change the level of post-operative pain following endodontic treatment as measured by the VAS scale.~Pain measurements were made using a 0-100 VAS- NRS. The '0' mark represented 'no pain' and the '100' mark represented 'the worst pain imaginable'. Scores 0-19 represented low pain, 20-39 was mild pain, 40-59 was moderate pain, 60-79 was high pain, and 80-100 was very high or severe pain. For this study, scores in the very high range were considered severe pain." (NCT03635515)
Timeframe: 72 hours
| Intervention | score on VAS scale (Mean) |
|---|---|
| Standard Protocol (Control) Group | 17 |
| Gentlewave Treatment Group | 15 |
Evaluate time to hospital discharge from out of OR time in minutes (NCT03860259)
Timeframe: Day of surgery through time of discharge, up to 270 min post-operative
| Intervention | minutes (Mean) |
|---|---|
| Auriculotherapy Without Nitrogen Gas | 140.1 |
| Auriculotherapy With Nitrogen Gas | 148.0 |
Evaluate time to readiness for discharge from post-anesthesia care unit (PACU) from out of OR time in minutes (NCT03860259)
Timeframe: Day of surgery through recovery room discharge, up to 142 min post-operative
| Intervention | minutes (Mean) |
|---|---|
| Auriculotherapy Without Nitrogen Gas | 59.5 |
| Auriculotherapy With Nitrogen Gas | 67.2 |
The number of participants who experienced complications and received the standard protocol versus subjects who received the standard protocol + Auriculotherapy. Post-operative complications can be defined as unexpected problems that arise following surgery including increased bleeding, infection, recurrent rotator cuff tear, and displacement of suture anchor. (NCT03860259)
Timeframe: Day of surgery through 90-days post-operative
| Intervention | Participants (Count of Participants) |
|---|---|
| Auriculotherapy Without Nitrogen Gas | 0 |
| Auriculotherapy With Nitrogen Gas | 0 |
Participants are asked to assess their overall satisfaction with care upon discharge on a 10-point satisfaction scale of 0 (least satisfaction) to 10 (highest satisfaction). The lowest possible score is 0 and the highest possible score is 10. Higher scores represent a better outcome. (NCT03860259)
Timeframe: Day of surgery through time of discharge, up to 270 min post-operative
| Intervention | score on a scale (Mean) |
|---|---|
| Auriculotherapy Without Nitrogen Gas | 9.2 |
| Auriculotherapy With Nitrogen Gas | 9.6 |
Evaluate the number of subjects readmitted to the hospital for post-operative complications other than pain-related issues. (NCT03860259)
Timeframe: Day of surgery through 90-days post-operative
| Intervention | Participants (Count of Participants) |
|---|---|
| Auriculotherapy Without Nitrogen Gas | 0 |
| Auriculotherapy With Nitrogen Gas | 0 |
Evaluate the number of subjects readmitted because of pain or pain-related issues during the 90 day study duration (NCT03860259)
Timeframe: Day of surgery through 90-days post-operative
| Intervention | participants (Number) |
|---|---|
| Auriculotherapy Without Nitrogen Gas | 0 |
| Auriculotherapy With Nitrogen Gas | 0 |
Functional recovery will be measured by the assessment of the participant's answers to the Functional Recovery Questionnaire 12-Item Short Form Health Survey (SF-12). The SF-12 Health Survey includes questions from the SF-36 Health Survey (Version 1). Two summary scores are reported from the SF-12 - a mental component score (MCS-12) and a physical component score (PCS-12). The United States population average PCS-12 and MCS-12 are both 50 points. The United States population average PCS-12 and MCS-12 are both 50 points. The United States population standard deviation is 10 points. So each 10 increment of 10 points above or below 50, corresponds to one standard deviation away from the average. The highest possible PCS-12 score is 56.57706 and the lowest possible score is 23.99938. The highest possible MCS-12 score is 67.37178 and the lowest possible score is 17.57825. Higher scores for both represent better functioning. (NCT03860259)
Timeframe: Day of surgery through 90 days post-operative
| Intervention | score on a scale (Mean) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Baseline PCS | Day 14 PCS | Day 30 PCS | Day 60 PCS | Day 90 PCS | Baseline MCS | Day 14 MCS | Day 30 MCS | Day 60 MCS | Day 90 MCS | |
| Auriculotherapy With Nitrogen Gas | 38.0 | 34.0 | 35.7 | 39.0 | 44.9 | 59.4 | 60.3 | 59.6 | 58.6 | 58.3 |
| Auriculotherapy Without Nitrogen Gas | 38.9 | 37.1 | 36.1 | 40.5 | 44.1 | 60.5 | 57.4 | 61.3 | 59.9 | 60.8 |
Investigate the efficacy of auriculotherapy in reducing total perioperative consumption of non-narcotic analgesics. (NCT03860259)
Timeframe: Day of surgery through 5-days post-operative
| Intervention | milligrams (Mean) | |
|---|---|---|
| Acetaminophen | Ibuprofen | |
| Auriculotherapy With Nitrogen Gas | 5955.63 | 1370.00 |
| Auriculotherapy Without Nitrogen Gas | 4438.16 | 785.26 |
Investigate the efficacy of auriculotherapy in reducing perioperative opioid consumption in opioid-naïve patients undergoing elective rotator cuff surgery. This is reported in consumption of oral morphine mg equivalents (OME) at 24 hrs, 48 hrs, 72 hrs, 96 hrs, and 120 hrs post-operative as well as the total sum of these intervals (NCT03860259)
Timeframe: 24 hrs, 48 hrs, 72 hrs, 96 hrs, and 120 hrs post-operative
| Intervention | oral morphine mg equivalents (OME) (Mean) | |||||
|---|---|---|---|---|---|---|
| 24 Hours | 48 Hours | 72 Hours | 96 Hours | 120 Hours | Total | |
| Auriculotherapy With Nitrogen Gas | 25 | 21 | 12 | 9 | 5 | 62 |
| Auriculotherapy Without Nitrogen Gas | 31 | 25 | 19 | 12 | 10 | 96 |
Numerical Rating Scale (NRS) pain at rest on a scale from 0-10, with 0 being no pain, 5 being moderate pain and 10 being the worst imaginable pain. The lowest possible score is 0 and the highest possible score is 10. Higher scores represent a worse outcome. (NCT03860259)
Timeframe: Time of discharge through 90-days post-operative
| Intervention | score on a scale (Mean) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Discharge | 24 Hours | 48 Hours | 72 Hours | 96 Hours | 120 Hours | Day 14 | Day 30 | Day 60 | Day 90 | |
| Auriculotherapy With Nitrogen Gas | 0.45 | 5.75 | 4.50 | 3.50 | 3.45 | 2.65 | 1.71 | 1.20 | 1.21 | 0.38 |
| Auriculotherapy Without Nitrogen Gas | 0.89 | 6.17 | 4.67 | 3.89 | 3.50 | 2.88 | 2.26 | 2.13 | 1.23 | 0.43 |
Numerical Rating Scale (NRS) Pain with movement on a scale from 0-10, with 0 being no pain, 5 being moderate pain and 10 being the worst imaginable pain. The lowest possible score is 0 and the highest possible score is 10. Higher scores represent a worse outcome. (NCT03860259)
Timeframe: 24 hrs through 90-days post-operative
| Intervention | score on a scale (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 24 Hours | 48 Hours | 72 Hours | 96 Hours | 120 Hours | Day 14 | Day 30 | Day 60 | Day 90 | |
| Auriculotherapy With Nitrogen Gas | 7.42 | 6.21 | 5.37 | 4.65 | 3.80 | 4.47 | 5.27 | 3.64 | 2.00 |
| Auriculotherapy Without Nitrogen Gas | 8.11 | 6.83 | 6.28 | 5.44 | 4.72 | 5.84 | 5.00 | 4.15 | 2.21 |
Participants are asked to assess their satisfaction with pain management at discharge, 24 hrs, 48 hrs, 72 hrs, 96, hours, 120 hrs and 14 days, 30 days, 60 days and 90 days post-operative on a 10-point satisfaction scale of 0 (least satisfaction) to 10 (highest satisfaction). The lowest possible score is 0 and the highest possible score is 10. Higher scores represent a better outcome. (NCT03860259)
Timeframe: Day of surgery through 90-days post-operative
| Intervention | score on a scale (Mean) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Discharge | 24 Hours | 48 Hours | 72 Hours | 96 Hours | 120 Hours | Day 14 | Day 30 | Day 60 | Day 90 | |
| Auriculotherapy With Nitrogen Gas | 5.9 | 4.1 | 4.6 | 4.9 | 4.6 | 4.8 | 5.6 | 5.7 | 5.3 | 5.9 |
| Auriculotherapy Without Nitrogen Gas | 5.7 | 4.2 | 4.7 | 5.1 | 4.7 | 4.8 | 5.6 | 5.4 | 5.2 | 4.9 |
To assess need for additional intraoperative and/or postoperative pain medication (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
| Intervention | Participants (Count of Participants) |
|---|---|
| Hydrocodone/Acetaminophen | 0 |
| Placebo | 0 |
To determine whether HC/APAP, given in addition to a standard regimen of ibuprofen, lorazepam, and PCB, affects patient pain perception at the time of uterine aspiration, as measured by distance (mm) from the left of the 100 mm visual analog scale (VAS). The number 0 indicates no pain, and 100 indicates worst pain imaginable. (NCT01330459)
Timeframe: At time of uterine aspiration (baseline)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 65.7 |
| Placebo | 63.1 |
Distance (mm) from the left of the 100 mm VAS scale (VAS anchors: 0 = none, 100 mm = worst imaginable) recorded after cervical dilation (NCT01330459)
Timeframe: During procedure (approximately 45-90 min after hydrocodone/acetaminophen or placebo, and within 5 minutes of procedure starting)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 47.2 |
| Placebo | 43.9 |
To assess whether HC/APAP is associated with nausea, measured on the 100 mm VAS, recorded 30 minutes postoperatively. VAS anchors: 0 indicates no pain, and 100 indicates worst pain imaginable. (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 19.4 |
| Placebo | 11.4 |
Distance (mm) from the left of the 100 mm VAS (VAS anchors: 0 = unsatisfied, 100 mm = very satisfied) recorded 30 minutes after completion of the procedure. (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 74.8 |
| Placebo | 67.3 |
Cumulative opiate consumption (IV morphine equivalents) (NCT02487303)
Timeframe: 24 hours
| Intervention | mg (Mean) |
|---|---|
| Acetaminophen Intravenous | 2.9 |
| Acetaminophen Oral | 3.8 |
| No Acetaminophen | 5.7 |
Time patient meets discharge criteria will be recorded (NCT02487303)
Timeframe: 24 hours postoperative
| Intervention | hours (Mean) |
|---|---|
| Acetaminophen Intravenous | 48.4 |
| Acetaminophen Oral | 48.6 |
| No Acetaminophen | 50.5 |
Time to first opiate pain medicine requested by patient (NCT02487303)
Timeframe: 48 hours
| Intervention | hours (Mean) |
|---|---|
| Acetaminophen Intravenous | 25.3 |
| Acetaminophen Oral | 24.0 |
| No Acetaminophen | 21.3 |
"Visual Analog Scale (VAS) pain assessment with ambulation. The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between no pain and worst pain. For pain intensity, the scale is most commonly anchored by no pain (score of 0) and pain as bad as it could be or worst imaginable pain (score of 100 [100-mm scale]) ." (NCT02487303)
Timeframe: 24 hours
| Intervention | units on a scale (Mean) |
|---|---|
| Acetaminophen Intravenous | 37.8 |
| Acetaminophen Oral | 44.3 |
| No Acetaminophen | 50.8 |
Using the Faces Pain Scale, the pediatric patient will indicate his/her pain level at scheduled intervals (7 times per day) for 14 days post-surgery.The Faces Pain Scale Revised is a dimensionless 10 point likert scale used to assess self-reported pain intensity on a scale from 0 (no pain) to 10 (most pain you can imagine). Greater pain scores are indicative of more severe pain. For this analysis, participant pain scores were summed and the mean per group was calculated. Total summed scores could range from 0 to 980. (NCT02296840)
Timeframe: 2 weeks after surgery
| Intervention | units on a scale (Mean) |
|---|---|
| Ibuprofen | 158.95 |
| Hydrocodone-acetaminophen | 219.94 |
The occurrence of post-operative bleeding at the surgical site for each participant will be assessed by review of the participant's study records and clinical records and by questioning the caregiver in follow-up. If postoperative bleeding has occurred, details of the episode of bleeding will also be obtained (requirement for surgical intervention, observation at home, or observation at the hospital). (NCT02296840)
Timeframe: 2 weeks after surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Ibuprofen | 2 |
| Hydrocodone-acetaminophen | 0 |
"Marginal mean pain scores via Numeric Rating Scale (NRS-11) over 24 hours. The scale is from 0 to 10, where 0 represents no pain and 10 represents the worst pain possible." (NCT03480009)
Timeframe: Marginal mean pain scores over 24 hours
| Intervention | score on a scale (NRS-11) (Mean) |
|---|---|
| Dextromethorphan, Opted for Narcotic Prescription | 2.93 |
| Placebo, Opted for Narcotic Prescription | 2.96 |
| Dextromethorphan, Declined Narcotic Prescription | 2.70 |
| Placebo, Declined Narcotic Prescription | 2.41 |
"Self-reported pain measurement via text-messaging system during first 24 hours after misoprostol administration. The scale is from 0 to 10, where 0 represents no pain and 10 represents the worst pain possible." (NCT03480009)
Timeframe: Over 24 hours starting from misoprostol administration
| Intervention | score on a scale (Median) |
|---|---|
| Dextromethorphan, Opted for Narcotic Prescription | 8.0 |
| Placebo, Opted for Narcotic Prescription | 7.0 |
| Dextromethorphan, Declined Narcotic Prescription | 7.5 |
| Placebo, Declined Narcotic Prescription | 6.5 |
Analgesic usage by study arm for women who received dextromethorphan vs. placebo as adjunct to routine pain management during medication abortion; missing data are for participants who did not take the specified pain medication. (NCT03480009)
Timeframe: Over 24 hours
| Intervention | mg (Median) | |
|---|---|---|
| ibuprofen | 9acetaminophen | |
| Dextromethorphan, Declined Narcotic Prescription | 800 | 800 |
Analgesic usage by study arm for women who received dextromethorphan vs. placebo as adjunct to routine pain management during medication abortion; missing data are for participants who did not take the specified pain medication. (NCT03480009)
Timeframe: Over 24 hours
| Intervention | mg (Median) | ||
|---|---|---|---|
| ibuprofen | 9acetaminophen | oxycodone | |
| Dextromethorphan, Opted for Narcotic Prescription | 800 | 1000 | 10 |
| Placebo, Declined Narcotic Prescription | 1000 | 975 | 15 |
| Placebo, Opted for Narcotic Prescription | 600 | 1300 | 15 |
48 reviews available for ibuprofen and Pain, Postoperative
| Article | Year |
|---|---|
Single-dose intravenous ibuprofen for acute postoperative pain in adults.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Femal | 2021 |
Post-Tonsillectomy Ibuprofen: Is There a Dose-Dependent Bleeding Risk?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Pain, Postoperative; Postoperative Hemor | 2022 |
Pain Relief with Combination Acetaminophen/Codeine or Ibuprofen following Third-Molar Extraction: A Systematic Review and Meta-Analysis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Codeine; Double-Blind Method; Drug Combinations; Humans; Ib | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Down the canal or down the gullet - which form of ibuprofen is best for post-endo instrumentation pain?
Topics: Humans; Ibuprofen; Observational Studies as Topic; Pain, Postoperative; Periapical Periodontitis; Ra | 2022 |
Down the canal or down the gullet - which form of ibuprofen is best for post-endo instrumentation pain?
Topics: Humans; Ibuprofen; Observational Studies as Topic; Pain, Postoperative; Periapical Periodontitis; Ra | 2022 |
Down the canal or down the gullet - which form of ibuprofen is best for post-endo instrumentation pain?
Topics: Humans; Ibuprofen; Observational Studies as Topic; Pain, Postoperative; Periapical Periodontitis; Ra | 2022 |
Down the canal or down the gullet - which form of ibuprofen is best for post-endo instrumentation pain?
Topics: Humans; Ibuprofen; Observational Studies as Topic; Pain, Postoperative; Periapical Periodontitis; Ra | 2022 |
Acute Postoperative Pain Due to Dental Extraction in the Adult Population: A Systematic Review and Network Meta-analysis.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Human | 2023 |
Intravenous ibuprofen in postoperative pain and fever management in adults: A systematic review and meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Adult; Antipyretics; Fever; Humans; Ibuprofen; Pain, Postoperative; Randomized Contro | 2023 |
Efficacy and Safety of Ibuprofen Plus Paracetamol in a Fixed-Dose Combination for Acute Postoperative Pain in Adults: Meta-Analysis and a Trial Sequential Analysis.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Drug Combinations; Humans; Ibuprofen; Pain, Postoper | 2021 |
Systematic Review and Meta-Analysis of the Association Between Non-Steroidal Anti-Inflammatory Drugs and Operative Bleeding in the Perioperative Period.
Topics: Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical; Blood Transfusion; Diclofe | 2021 |
Effect of single dose preoperative intravenous ibuprofen on postoperative pain and opioid consumption: a systematic review and meta-analysis.
Topics: Administration, Intravenous; Analgesics, Opioid; Fentanyl; Humans; Ibuprofen; Pain, Postoperative | 2021 |
Pain Management in Children: NSAID Use in the Perioperative and Emergency Department Settings.
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; Drug-Related Side Effects and Ad | 2021 |
Pharmacological and Non-Pharmacological Methods of Postoperative Pain Control Following Oral and Maxillofacial Surgery: A Scoping Review.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Pain, | 2021 |
Analgesic effectiveness and safety of celecoxib versus non-opioid active controls after third molar surgery: A meta-analytical evaluation.
Topics: Analgesics; Celecoxib; Humans; Ibuprofen; Molar, Third; Nausea; Pain, Postoperative; Vomiting | 2022 |
Updates on Multimodal Analgesia for Orthopedic Surgery.
Topics: Acetaminophen; Amines; Analgesia; Celecoxib; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobut | 2018 |
The Use of Intravenous Ibuprofen and Intravenous Acetaminophen in Surgical Patients and the Effect on Opioid Reduction.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Female; Humans; Ibuprofe | 2017 |
Ibuprofen in the treatment of children's inflammatory pain: a clinical and pharmacological overview.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Humans; Ibuprofen; Inflamm | 2019 |
Efficacy and Safety of Oral Premedication on Pain after Nonsurgical Root Canal Treatment: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Databases, B | 2019 |
Postoperative Pain Management in Dermatologic Surgery: A Systematic Review.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Dermatologic Surgical Procedures; Humans; Ibuprofen; | 2019 |
Postoperative Bleeding Associated with Ibuprofen Use after Tonsillectomy: A Meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Pain, Postoperative; Postoperative Hemor | 2019 |
Single dose oral ibuprofen plus codeine for acute postoperative pain in adults.
Topics: Adult; Analgesics, Opioid; Codeine; Drug Combinations; Humans; Ibuprofen; Pain, Postoperative; Rando | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus oxycodone for acute postoperative pain in adults.
Topics: Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Combinat | 2013 |
Pharmacotherapy for the prevention of chronic pain after surgery in adults.
Topics: Adrenal Cortex Hormones; Adult; Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Femal | 2013 |
Combining ibuprofen and acetaminophen for acute pain management after third-molar extractions: translating clinical research to dental practice.
Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug C | 2013 |
Single dose oral dexibuprofen [S(+)-ibuprofen] for acute postoperative pain in adults.
Topics: Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Ste | 2013 |
Ibuprofen and/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Drug Combinations; Drug Therapy, Comb | 2013 |
Caffeine as an analgesic adjuvant for acute pain in adults.
Topics: Acetaminophen; Acute Pain; Adolescent; Adult; Aged; Analgesics; Caffeine; Chemotherapy, Adjuvant; Di | 2014 |
Single dose oral ibuprofen plus codeine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics, Opioid; Codeine; Drug Combinations; Humans; Ibuprofen; Pain, Postoper | 2015 |
Single dose oral ibuprofen plus caffeine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics, Non-Narcotic; Caffeine; Drug Combinations; Humans; Ibuprofen; Numbers | 2015 |
Ibuprofen May Not Increase Bleeding Risk in Plastic Surgery: A Systematic Review and Meta-Analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Models, Statistical; Pain, Postoperative | 2016 |
Nonsteroidal Anti-inflammatory Drugs for Managing Postoperative Endodontic Pain in Patients Who Present with Preoperative Pain: A Systematic Review and Meta-analysis.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Naproxen; Pain | 2017 |
Single dose oral ibuprofen for acute postoperative pain in adults.
Topics: Administration, Oral; Adult; Analgesics, Non-Narcotic; Humans; Ibuprofen; Pain, Postoperative; Rando | 2009 |
Single dose oral dexibuprofen [S(+)-ibuprofen] for acute postoperative pain in adults.
Topics: Acute Disease; Administration, Oral; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non- | 2009 |
Evidence-based review of clinical studies on pharmacology (non-anesthetic studies).
Topics: Acetaminophen; Administration, Oral; Analgesics; Anxiety; Dental Pulp Diseases; Dexamethasone; Drug | 2009 |
Minimum efficacy criteria for comparisons between treatments using individual patient meta-analysis of acute pain trials: examples of etoricoxib, paracetamol, ibuprofen, and ibuprofen/paracetamol combinations after third molar extraction.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Double-Blind Method; Drug Therapy, Combination; Etoricoxib; | 2011 |
Caffeine as an analgesic adjuvant for acute pain in adults.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Caffeine; Chemotherapy, Adjuvant; Female; Headache; Hu | 2012 |
[Postoperative pain therapy in otolaryngological department].
Topics: Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Analgesics, Non-Narcotic; | 2006 |
Standardised analgesia packs after day case orthopaedic surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Attitude to Health; Codeine; D | 2007 |
Analgesic efficacy in dental pain.
Topics: Acetaminophen; Adult; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; | 1982 |
Nonsteroidal anti-inflammatory agents in relieving dental pain: a review.
Topics: Analgesics; Anti-Inflammatory Agents; Chemical Phenomena; Chemistry; Drug Interactions; Humans; Ibup | 1983 |
New peripherally-acting oral analgesic agents.
Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials | 1983 |
Non-steroidal anti-inflammatory drugs (NSAID'S) as analgesics in dentistry - a review.
Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Dental Care; Diflunisal; Humans; Ibuprofen; Indometha | 1983 |
Peri-operative use of nonsteroidal anti-inflammatory drugs in children: analgesic efficacy and bleeding.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Diclofenac; Drug Admin | 1997 |
Analgesic efficacy of ibuprofen alone and in combination with codeine or caffeine in post-surgical pain: a meta-analysis.
Topics: Adult; Anesthetics, Combined; Caffeine; Codeine; Dose-Response Relationship, Drug; Drug Synergism; H | 1998 |
Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opio | 1998 |
Single dose oral ibuprofen and diclofenac for postoperative pain.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Ibuprofen; Pa | 2000 |
Single dose dihydrocodeine for acute postoperative pain.
Topics: Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Humans; Ibuprofen; Pain, Posto | 2000 |
Preoperative nonsteroidal anti-inflammatory medication for the prevention of postoperative dental pain.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Flurbiprofen; Humans; Ibuprofen; Mouth; Pain, Postoperative | 1989 |
360 trials available for ibuprofen and Pain, Postoperative
| Article | Year |
|---|---|
Pain Management Following Otological Surgery: A Prospective Study of Different Strategies.
Topics: Acetaminophen; Adult; Aged; Analgesics; Cochlear Implantation; Codeine; Ear, Middle; Female; Humans; | 2022 |
Analgesic effect of oral ibuprofen 400, 600, and 800 mg; paracetamol 500 and 1000 mg; and paracetamol 1000 mg plus 60 mg codeine in acute postoperative pain: a single-dose, randomized, placebo-controlled, and double-blind study.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Codeine; Dose-Response Relationship, Drug; Double-Blin | 2021 |
The Use of Combination Paracetamol and Ibuprofen in Postoperative Pain after Total Knee Arthroplasty, a Randomized Controlled Trial.
Topics: Acetaminophen; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Double-Blind Method; Humans; Ibu | 2021 |
COMPARATIVE ANALGESIC EFFECTS OF SINGLE-DOSE PREOPERATIVE ADMINISTRATION OF PARACETAMOL (ACETAMINOPHEN) 500 mg PLUS CODEINE 30 mg AND IBUPROFEN 400 mg ON PAIN AFTER THIRD MOLAR SURGERY.
Topics: Acetaminophen; Analgesics; Codeine; Double-Blind Method; Humans; Ibuprofen; Molar, Third; Pain, Post | 2021 |
ANALGESIC EFFICACY OF TRAMADOL/DEXKETOPROFEN VS IBUPROFEN AFTER IMPACTED LOWER THIRD MOLAR EXTRACTION: A RANDOMIZED CONTROLLED CLINICAL TRIAL.
Topics: Analgesics; Double-Blind Method; Drug Combinations; Humans; Ibuprofen; Ketoprofen; Molar, Third; Pai | 2021 |
Effect of dexamethasone as an analgesic adjuvant to multimodal pain treatment after total knee arthroplasty: randomised clinical trial.
Topics: Acetaminophen; Aged; Analgesics; Arthroplasty, Replacement, Knee; Dexamethasone; Double-Blind Method | 2022 |
Time to Stop Routinely Prescribing Opiates after Carpal Tunnel Release.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Canada; Carpal Tunnel Synd | 2022 |
NSAID chronotherapy after impacted third molar extraction: a randomized controlled trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronotherapy; Double-Blind Method; Humans; Ibuprofen; Infl | 2022 |
Intravenous ibuprofen versus diclofenac plus orphenadrine in orthognathic surgery: a prospective, randomized, double-blind, controlled clinical study.
Topics: Acetaminophen; Adolescent; Adult; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Middle Aged; O | 2022 |
Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy/Adenoidectomy: A Pilot Study.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Aftercare; Analgesics; Analgesics, Opioid; Child; Child, P | 2022 |
Efficacy of Intravenous Ibuprofen and Intravenous Paracetamol in Multimodal Pain Management of Postoperative Pain After Percutaneous Nephrolithotomy.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Double-Bl | 2022 |
Analgesic benefit of metamizole and ibuprofen vs. either medication alone: a randomized clinical trial.
Topics: Analgesics; COVID-19; Cross-Over Studies; Dipyrone; Double-Blind Method; Humans; Ibuprofen; Pain, Po | 2022 |
Lack of Evidence for Blood Pressure Effects of Caffeine Added to Ibuprofen.
Topics: Analgesics, Non-Narcotic; Blood Pressure; Caffeine; Double-Blind Method; Humans; Ibuprofen; Pain; Pa | 2023 |
Comparative Evaluation of Preemptive and Preventive Analgesic Effect of Oral Ibuprofen in Single Visit Root Canal Treatment- A Prospective Randomised Pilot Study.
Topics: Analgesics; Dental Pulp Cavity; Humans; Ibuprofen; Pain, Postoperative; Pilot Projects; Prospective | 2022 |
A prospective randomized study evaluating the necessity of narcotics following ureteroscopy for urinary stone disease.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 2022 |
Effect of time-dependent ibuprofen administration on the post operatory after impacted third molar extraction: a cross-over randomized controlled trial.
Topics: Cross-Over Studies; Double-Blind Method; Edema; Humans; Ibuprofen; Molar, Third; Pain, Postoperative | 2023 |
Comparison of Local and Systemic Ibuprofen for Relief of Postoperative Pain in Symptomatic Teeth with Apical Periodontitis.
Topics: Humans; Ibuprofen; Pain, Postoperative; Periapical Periodontitis; Root Canal Irrigants; Root Canal P | 2022 |
Comparison of intravenous ibuprofen versus ketorolac for postoperative analgesia in children undergoing lower abdominal surgery: A randomized, controlled, non-inferiority study.
Topics: Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Child; Double-Blind Method; Humans; Ibuprofen; K | 2022 |
Comparison of intravenous ibuprofen and tenoxicam efficiency in ankle injury: a randomized, double-blind study.
Topics: Analgesics; Ankle Injuries; Double-Blind Method; Humans; Ibuprofen; Pain, Postoperative; Prospective | 2023 |
Paracetamol, ibuprofen and dexamethasone for pain treatment after total hip arthroplasty: protocol for the randomised, placebo-controlled, parallel 4-group, blinded, multicentre RECIPE trial.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty | 2022 |
A randomized, placebo-controlled study of magnetic acupuncture for supplementary analgesia after laparoscopic appendectomy in children.
Topics: Acetaminophen; Acupuncture Therapy; Adolescent; Analgesia; Analgesics; Appendectomy; Child; Child, P | 2023 |
The Analgesic Effects of the Addition of Intravenous Ibuprofen to a Multimodal Analgesia Regimen for Pain Management After Pediatric Cardiac Surgery: A Randomized Controlled Study.
Topics: Analgesia; Analgesics, Opioid; Cardiac Surgical Procedures; Child; Double-Blind Method; Fentanyl; Hu | 2023 |
The Analgesic Effects of the Addition of Intravenous Ibuprofen to a Multimodal Analgesia Regimen for Pain Management After Pediatric Cardiac Surgery: A Randomized Controlled Study.
Topics: Analgesia; Analgesics, Opioid; Cardiac Surgical Procedures; Child; Double-Blind Method; Fentanyl; Hu | 2023 |
The Analgesic Effects of the Addition of Intravenous Ibuprofen to a Multimodal Analgesia Regimen for Pain Management After Pediatric Cardiac Surgery: A Randomized Controlled Study.
Topics: Analgesia; Analgesics, Opioid; Cardiac Surgical Procedures; Child; Double-Blind Method; Fentanyl; Hu | 2023 |
The Analgesic Effects of the Addition of Intravenous Ibuprofen to a Multimodal Analgesia Regimen for Pain Management After Pediatric Cardiac Surgery: A Randomized Controlled Study.
Topics: Analgesia; Analgesics, Opioid; Cardiac Surgical Procedures; Child; Double-Blind Method; Fentanyl; Hu | 2023 |
Pain treatment after total hip arthroplasty: Detailed statistical analysis plan for the RECIPE randomised clinical trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Humans; | 2023 |
The Effect of Trypsin-Chymotrypsin on Postoperative Pain after Single Visit Endodontic Treatment: A Randomized Controlled Trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chymotrypsin; Double-Blind Method; Humans; Ibuprofen; Pain, | 2023 |
Additive or synergistic analgesic effect of metamizole on standard pain treatment at home after arthroscopic shoulder surgery: A randomised controlled superiority trial.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Humans; Ibuprofen; Pain, Postopera | 2023 |
Analgesic Efficacy of Intravenous Ibuprofen in the Treatment of Postoperative Acute Pain: A Phase III Multicenter Randomized Placebo-ControlledDouble-Blind Clinical Trial.
Topics: Acute Pain; Analgesics; Analgesics, Opioid; Double-Blind Method; Humans; Ibuprofen; Morphine; Pain, | 2023 |
Analgesic Efficacy of Ibuprofen and Diclofenac Potassium on Postoperative Endodontic Pain in Maxillary and Mandibular First Molars with Irreversible Pulpitis: A Randomised Controlled Trial.
Topics: Analgesics; Diclofenac; Humans; Ibuprofen; Molar; Pain, Postoperative; Prospective Studies; Pulpitis | 2023 |
Efficiency of Immediate and Controlled release of Aceclofenac on Post-instrumentation Pain in Root Canal Treatment - A Triple Blind Randomized Controlled Trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Dental Pulp Cavity; Double-Bli | 2023 |
Outpatient Treatment With Gabapentin in Women With Severe Acute Pain After Cesarean Delivery Is Ineffective: A Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Acetaminophen; Acute Pain; Analgesics, Opioid; Double-Blind Method; Female; Gabapentin; Humans; Ibup | 2023 |
A Multi-Center Evaluation of the Pharmacokinetics and Safety of Intravenous Ibuprofen in Infants 1-6 Months of Age.
Topics: Administration, Intravenous; Aged; Child; Female; Fever; Humans; Ibuprofen; Infant; Infant, Newborn; | 2023 |
Analgesic Efficacy of Ketoprofen Transdermal Patch versus Ibuprofen Oral Tablet on Postendodontic Pain in Patients with Irreversible Pulpitis: A Randomized Clinical Trial.
Topics: Analgesics; Double-Blind Method; Humans; Ibuprofen; Ketoprofen; Pain, Postoperative; Pulpitis; Trans | 2023 |
Analgesic effect of oral paracetamol 1000 mg/ibuprofen 400 mg, paracetamol 1000 mg/codeine 60 mg, paracetamol 1000 mg/ibuprofen 400 mg/codeine 60 mg, or placebo on acute postoperative pain: a single-dose, randomized, and double-blind study.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Codeine; Double-Blind Method; Drug-Relat | 2023 |
Combination of acetaminophen and ibuprofen is noninferior to acetaminophen and hydrocodone for postnail procedure analgesia: A randomized controlled trial.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Drug Combinations; Humans; Hydrocodone; Ibuprofe | 2023 |
Preemptive effects of etoricoxib, acetaminophen, nimesulide, and ibuprofen on postoperative pain management after single-implant surgery: A randomized clinical trial.
Topics: Acetaminophen; Dental Implants; Double-Blind Method; Etoricoxib; Female; Humans; Ibuprofen; Male; Mi | 2023 |
Efficacy and Safety of an Intravenous Acetaminophen/Ibuprofen Fixed-dose Combination After Bunionectomy: a Randomized, Double-blind, Factorial, Placebo-controlled Trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia; Analgesics; Anti-Inflammatory Agents, Non-Steroid | 2019 |
Benefits and harm of paracetamol and ibuprofen in combination for post-operative pain: Pre-planned subgroup analyses of the multicenter, randomized PANSAID trial.
Topics: Acetaminophen; Aged; Aged, 80 and over; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; | 2020 |
IV Ibuprofen for Prevention of Post-ERCP Pancreatitis in Children: A Randomized Placebo-controlled Feasibility Study.
Topics: Abdominal Pain; Administration, Intravenous; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Ch | 2020 |
A randomized pilot program to reduce opioid use following dental surgery and increase safe medication return.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans; Ibuprofen; Male; | 2020 |
Comparison of the effect of photobiomodulation therapy and Ibuprofen on postoperative pain after endodontic treatment: randomized, controlled, clinical study.
Topics: Adult; Endodontics; Female; Humans; Ibuprofen; Low-Level Light Therapy; Male; Pain Measurement; Pain | 2020 |
An Evaluation of Ibuprofen Versus Ibuprofen/Acetaminophen for Postoperative Endodontic Pain in Patients With Symptomatic Irreversible Pulpitis and Symptomatic Apical Periodontitis.
Topics: Acetaminophen; Adult; Double-Blind Method; Endodontics; Female; Humans; Ibuprofen; Male; Pain, Posto | 2019 |
Intravenous Ibuprofen Reduces Opioid Consumption During the Initial 48 Hours After Injury in Orthopedic Trauma Patients.
Topics: Administration, Intravenous; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Huma | 2020 |
Randomized control trial of opioid- versus nonopioid-based analgesia after thyroidectomy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans; Ibuprofen; Male; Middle | 2020 |
Does the pre-emptive administration of paracetamol or ibuprofen reduce trans- and post-operative pain in primary molar extraction? A randomized placebo-controlled clinical trial.
Topics: Acetaminophen; Child; Double-Blind Method; Humans; Ibuprofen; Molar; Pain, Postoperative; Tooth Extr | 2020 |
The PANSAID randomized clinical trial: A pre-planned 1-year follow-up regarding harm.
Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Denmark; Drug Therapy, Combination; Follow-Up S | 2020 |
Efficacy and Safety of Single and Multiple Doses of a Fixed-dose Combination of Ibuprofen and Acetaminophen in the Treatment of Postsurgical Dental Pain: Results From 2 Phase 3, Randomized, Parallel-group, Double-blind, Placebo-controlled Studies.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Double-Blind Method; Drug Combinations; Humans; Ibuprofen; | 2020 |
The Impact of Baseline Pain Intensity on the Analgesic Efficacy of Ibuprofen/Caffeine in Patients with Acute Postoperative Dental Pain: Post Hoc Subgroup Analysis of a Randomised Controlled Trial.
Topics: Acute Pain; Adolescent; Adult; Analgesics; Caffeine; Dose-Response Relationship, Drug; Double-Blind | 2020 |
Evaluation of Fixed-Dose Combinations of Ibuprofen and Acetaminophen in the Treatment of Postsurgical Dental Pain: A Pilot, Dose-Ranging, Randomized Study.
Topics: Acetaminophen; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, | 2020 |
Examining Reduced Opioid Prescriptions after Gynecologic Laparoscopy: A Randomized Controlled Trial.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Dose-Response Relationship | 2021 |
The efficacy of etodolac and ibuprofen, regarding gender, on pain, edema and trismus after impacted lower third molar surgery: A randomized prospective clinical split-mouth study.
Topics: Adolescent; Adult; Edema; Etodolac; Female; Humans; Ibuprofen; Male; Molar, Third; Mouth; Pain, Post | 2021 |
Opioid prescription for pain after osmotic dilator placement in abortion care: A randomized controlled trial.
Topics: Analgesics, Opioid; Double-Blind Method; Female; Humans; Ibuprofen; Oxycodone; Pain; Pain, Postopera | 2021 |
Comparison of Monotherapy Versus Combination of Intravenous Ibuprofen and Propacetamol (Acetaminophen) for Reduction of Postoperative Opioid Administration in Children Undergoing Laparoscopic Hernia Repair: A Double-Blind Randomized Controlled Trial.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroi | 2021 |
Using Intravenous Ibuprofen for Preventive Analgesia in Orthognathic Surgery.
Topics: Adult; Analgesics, Opioid; Double-Blind Method; Humans; Ibuprofen; Orthognathic Surgery; Pain Manage | 2021 |
Comparison of 3 protocols for analgesia control after cesarean delivery: a randomized controlled trial.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Adult; Analgesia; Analgesics; Anal | 2019 |
Effects of ibuprofen administration timing on oral surgery pain: A randomized clinical trial.
Topics: Administration, Oral; Double-Blind Method; Humans; Ibuprofen; Molar, Third; Pain, Postoperative; Too | 2022 |
Influence of Genetic Polymorphisms on the Response to Tramadol, Ibuprofen, and the Combination in Patients With Moderate to Severe Pain After Dental Surgery.
Topics: Analgesics, Opioid; Double-Blind Method; Humans; Ibuprofen; Pain; Pain, Postoperative; Polymorphism, | 2021 |
Post-operative pain management for single-level lumbar disc herniation surgery: A comparison of betamethasone, ibuprofen, and pregabalin.
Topics: Betamethasone; Humans; Ibuprofen; Intervertebral Disc Displacement; Lumbar Vertebrae; Pain, Postoper | 2021 |
Efficacy of Intravenous Paracetamol and Ibuprofen on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery: Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Topics: Acetaminophen; Humans; Ibuprofen; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studi | 2021 |
Postoperative pain and edema control following different protocols of preemptive analgesia in the surgical removal of impacted third molars: A triple-blind parallel randomized placebo-controlled clinical trial.
Topics: Analgesia; Double-Blind Method; Edema; Humans; Ibuprofen; Molar, Third; Pain, Postoperative; Tooth E | 2021 |
Effect of intravenous dexamethasone on postoperative pain and swelling following periodontal flap surgery: A randomized controlled trial of patient-centered outcomes.
Topics: Acetaminophen; Analgesics; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Pain, Postoperativ | 2022 |
Preemptive effects of ibuprofen and nimesulide on postoperative pain control after open flap periodontal surgeries: A randomized placebo-controlled split-mouth clinical trial.
Topics: Double-Blind Method; Humans; Ibuprofen; Mouth; Pain, Postoperative; Sulfonamides; Tooth Extraction | 2022 |
Comparison of preemptive ibuprofen, acetaminophen, and placebo administration in reducing peri- and postoperative pain in primary tooth extraction: A randomized clinical trial.
Topics: Acetaminophen; Child; Double-Blind Method; Humans; Ibuprofen; Pain, Postoperative; Tooth, Deciduous | 2021 |
The erector spinae plane block can facilitate outpatient stone surgery by reducing breakthrough pain.
Topics: Acetaminophen; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Op | 2021 |
Does ibuprofen, prednisolone, or amoxicillin reduce post-tonsillectomy pain in children? A prospective randomized controlled trial.
Topics: Amoxicillin; Analgesics, Non-Narcotic; Child; Humans; Ibuprofen; Pain, Postoperative; Prednisolone; | 2021 |
Educational Video on Pain Management and Subsequent Opioid Use After Cesarean Delivery: A Randomized Controlled Trial.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Cesarean Section; Female; Humans; Ibuprofen; Opioid-Relate | 2021 |
Extending the safety profile of the post-operative administration of an intravenous acetaminophen/ibuprofen fixed dose combination: An open-label, multi-center, single arm, multiple dose study.
Topics: Acetaminophen; Acute Pain; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesics, | 2021 |
Assessment of Opioid Use and Analgesic Requirements After Endoscopic Sinus Surgery: A Randomized Clinical Trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2021 |
Participants with mild, moderate, or severe pain following total hip arthroplasty. A sub-study of the PANSAID trial on paracetamol and ibuprofen for postoperative pain treatment.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Arthroplasty, Replacement, Hip; Humans; Ibuprofen; Pain, Po | 2021 |
Decreasing postoperative narcotics in reconstructive pelvic surgery: a randomized controlled trial.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Antiemetics; Celecoxib; Cyclohexanecarboxylic | 2017 |
Decreasing postoperative narcotics in reconstructive pelvic surgery: a randomized controlled trial.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Antiemetics; Celecoxib; Cyclohexanecarboxylic | 2017 |
Decreasing postoperative narcotics in reconstructive pelvic surgery: a randomized controlled trial.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Antiemetics; Celecoxib; Cyclohexanecarboxylic | 2017 |
Decreasing postoperative narcotics in reconstructive pelvic surgery: a randomized controlled trial.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Antiemetics; Celecoxib; Cyclohexanecarboxylic | 2017 |
Antibiotic treatment to prevent postextraction complications: a monocentric, randomized clinical trial. Preliminary outcomes.
Topics: Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Inflammatory | 2017 |
Efficacy of Codeine When Added to Paracetamol (Acetaminophen) and Ibuprofen for Relief of Postoperative Pain After Surgical Removal of Impacted Third Molars: A Double-Blinded Randomized Control Trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Double-Blind Method; Drug Ther | 2017 |
Effect of pre-emptive analgesia on clinical parameters and tissue levels of TNF-α and IL-1β in third molar surgery: a triple-blind, randomized, placebo-controlled study.
Topics: Adolescent; Adult; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Cyclooxyg | 2017 |
Efficacy and safety of a fixed-dose combination of ibuprofen and caffeine in the management of moderate to severe dental pain after third molar extraction.
Topics: Adolescent; Adult; Analgesics; Caffeine; Double-Blind Method; Drug Combinations; Female; Humans; Ibu | 2018 |
[Comparison of the differences in pain and the effect of ibuprofen in reducing endodontic flare-up after single-visit root canal therapy between Uyghur and Han patients with chronic apical periodontitis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Pain, Postoperative; Periapical Periodon | 2017 |
Effects of Addition of Preoperative Intravenous Ibuprofen to Pregabalin on Postoperative Pain in Posterior Lumbar Interbody Fusion Surgery.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; | 2017 |
PANSAID-PAracetamol and NSAID in combination: detailed statistical analysis plan for a randomised, blinded, parallel, four-group multicentre clinical trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2017 |
Absorption of ibuprofen orodispersible tablets in early postoperative phase - a pharmacokinetic study.
Topics: Administration, Oral; Adult; Aged; Biological Availability; Female; Humans; Ibuprofen; Male; Middle | 2018 |
Effects of Single-Dose Preemptive Pregabalin and Intravenous Ibuprofen on Postoperative Opioid Consumption and Acute Pain after Laparoscopic Cholecystectomy.
Topics: Administration, Intravenous; Adult; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Double- | 2019 |
What Is the Outcome of an Incision and Drainage Procedure in Endodontic Patients? A Prospective, Randomized, Single-blind Study.
Topics: Adult; Analgesics; Drainage; Female; Humans; Ibuprofen; Male; Pain Measurement; Pain, Postoperative; | 2018 |
The effect of flurbiprofen oral spray and ibuprofen vs ibuprofen alone on postoperative tonsillectomy pain: An open, randomised, controlled trial.
Topics: Adolescent; Adult; Analgesics; Drug Therapy, Combination; Female; Flurbiprofen; Humans; Ibuprofen; M | 2018 |
A Randomized Double-Blind Controlled Trial of Intravenous Meloxicam in the Treatment of Pain Following Dental Impaction Surgery.
Topics: Administration, Intravenous; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Dose-Respon | 2018 |
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Celecoxib; Cyclooxygenase | 2018 |
Preemptive Analgesia Decreases Pain Following Anorectal Surgery: A Prospective, Randomized, Double-Blinded, Placebo-Controlled Trial.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Amines; Anal Canal; Analgesics; Analgesics, Op | 2018 |
Comparison of intravenous ibuprofen and acetaminophen for postoperative multimodal pain management in bariatric surgery: A randomized controlled trial.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid | 2018 |
A prospective, randomized, double-blind, placebo-controlled trial of acute postoperative pain treatment using opioid analgesics with intravenous ibuprofen after radical cervical cancer surgery.
Topics: Acute Pain; Administration, Intravenous; Analgesics, Opioid; Double-Blind Method; Female; Humans; Ib | 2018 |
Do children undergoing bilateral myringotomy with placement of ventilating tubes benefit from pre-operative analgesia? A double-blinded, randomised, placebo-controlled trial.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Double-Blind Method; F | 2018 |
The comparison of single-dose preemptive intravenous ibuprofen and paracetamol on postoperative pain scores and opioid consumption after open septorhinoplasty: a randomized controlled study.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesia, Patient-Controlled; Analgesics; Analge | 2018 |
Analgesic Efficacy of an Acetaminophen/Ibuprofen Fixed-dose Combination in Moderate to Severe Postoperative Dental Pain: A Randomized, Double-blind, Parallel-group, Placebo-controlled Trial.
Topics: Acetaminophen; Acute Pain; Adolescent; Adult; Analgesics; Double-Blind Method; Drug Combinations; Fe | 2018 |
Pain Management After Carpal Tunnel Release Surgery: A Prospective Randomized Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2018 |
Does Pre-Emptive Administration of Intravenous Ibuprofen (Caldolor) or Intravenous Acetaminophen (Ofirmev) Reduce Postoperative Pain and Subsequent Narcotic Consumption After Third Molar Surgery?
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Bli | 2019 |
Analgesic effectiveness, pharmacokinetics, and safety of a paracetamol/ibuprofen fixed-dose combination in children undergoing adenotonsillectomy: A randomized, single-blind, parallel group trial.
Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Child; Child, Preschool; Drug Therapy, Combi | 2018 |
Comparison of Intravenous Ibuprofen and Paracetamol for Postoperative Pain Management after Laparoscopic Sleeve Gastrectomy. A Randomized Controlled Study.
Topics: Acetaminophen; Administration, Intravenous; Bariatric Surgery; Gastrectomy; Humans; Ibuprofen; Lapar | 2019 |
Comparison of Intravenous Ibuprofen and Paracetamol for Postoperative Pain Management after Laparoscopic Sleeve Gastrectomy. A Randomized Controlled Study.
Topics: Acetaminophen; Administration, Intravenous; Bariatric Surgery; Gastrectomy; Humans; Ibuprofen; Lapar | 2019 |
Comparison of Intravenous Ibuprofen and Paracetamol for Postoperative Pain Management after Laparoscopic Sleeve Gastrectomy. A Randomized Controlled Study.
Topics: Acetaminophen; Administration, Intravenous; Bariatric Surgery; Gastrectomy; Humans; Ibuprofen; Lapar | 2019 |
Comparison of Intravenous Ibuprofen and Paracetamol for Postoperative Pain Management after Laparoscopic Sleeve Gastrectomy. A Randomized Controlled Study.
Topics: Acetaminophen; Administration, Intravenous; Bariatric Surgery; Gastrectomy; Humans; Ibuprofen; Lapar | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
Comparative Analgesic Effects of Ibuprofen, Celecoxib and Tramadol after third Molar Surgery: A Randomized Double Blind Controlled Trial.
Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Double-Blind Meth | 2018 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Randomized Single-Blinded Trial of Ibuprofen- versus Opioid-Based Primary Analgesic Therapy in Outpatient Otolaryngology Surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analgesic | 2019 |
A Randomized Single-Blinded Trial of Ibuprofen- versus Opioid-Based Primary Analgesic Therapy in Outpatient Otolaryngology Surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analgesic | 2019 |
A Randomized Single-Blinded Trial of Ibuprofen- versus Opioid-Based Primary Analgesic Therapy in Outpatient Otolaryngology Surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analgesic | 2019 |
A Randomized Single-Blinded Trial of Ibuprofen- versus Opioid-Based Primary Analgesic Therapy in Outpatient Otolaryngology Surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analgesic | 2019 |
Evaluation of the efficacy of celecoxib and ibuprofen on postoperative pain, swelling, and mouth opening after surgical removal of impacted third molars: a randomized, controlled clinical trial.
Topics: Celecoxib; Double-Blind Method; Humans; Ibuprofen; Molar, Third; Pain, Postoperative; Tooth Extracti | 2019 |
Variability in the Analgesic Response to Ibuprofen Is Associated With Cyclooxygenase Activation in Inflammatory Pain.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Ibuprofen; Infl | 2019 |
Comparison of Ibuprofen vs Acetaminophen and Severe Bleeding Risk After Pediatric Tonsillectomy: A Noninferiority Randomized Clinical Trial.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Double-Blind Method; F | 2019 |
Comparison of Ibuprofen vs Acetaminophen and Severe Bleeding Risk After Pediatric Tonsillectomy: A Noninferiority Randomized Clinical Trial.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Double-Blind Method; F | 2019 |
Comparison of Ibuprofen vs Acetaminophen and Severe Bleeding Risk After Pediatric Tonsillectomy: A Noninferiority Randomized Clinical Trial.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Double-Blind Method; F | 2019 |
Comparison of Ibuprofen vs Acetaminophen and Severe Bleeding Risk After Pediatric Tonsillectomy: A Noninferiority Randomized Clinical Trial.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Double-Blind Method; F | 2019 |
Metamizole vs. ibuprofen at home after day case surgery: A double-blind randomised controlled noninferiority trial.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Ambulatory Surgical Procedures; Analgesics, | 2019 |
The effect of pregabalin and ibuprofen combination for pain after third molar surgery.
Topics: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Analgesics; Double-Blind Metho | 2019 |
A Randomized, Placebo-Controlled, Double-Blind Study that Evaluates Efficacy of Intravenous Ibuprofen and Acetaminophen for Postoperative Pain Treatment Following Laparoscopic Cholecystectomy Surgery.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Double-B | 2020 |
Low-dose preoperative pregabalin improves postoperative pain management in septorhinoplasty surgery: a double-blind randomized clinical trial.
Topics: Analgesics; Analgesics, Opioid; Double-Blind Method; Female; Fentanyl; Humans; Ibuprofen; Male; Midd | 2019 |
Pain Management After Surgical Tonsillectomy: Is There a Favorable Analgesic?
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Child; Female; Humans; I | 2019 |
Does Single-Dose Preemptive Intravenous Ibuprofen Reduce Postoperative Pain After Third Molar Surgery? A Prospective, Randomized, Double-Blind Clinical Study.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Humans; Ibuprofen; Molar, Third; | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Comparing Ketorolac With Ibuprofen for Postoperative Pain: A Randomized Clinical Trial.
Topics: Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; I | 2020 |
A comparison of postoperative pain after conventional open thyroidectomy and transaxillary single-incision robotic thyroidectomy: a prospective study.
Topics: Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Carcinoma; Carcinoma, Pap | 2013 |
Efficacy of anti-inflammatory drugs in third molar surgery: a randomized clinical trial.
Topics: Adolescent; Adult; Analysis of Variance; Anti-Inflammatory Agents; Dexamethasone; Dinoprostone; Doub | 2013 |
Efficacy of extended-release oral diclofenac in postoperative pain management after photorefractive keratectomy.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Astigmatism | 2013 |
A phase 3, randomized, double-blind comparison of analgesic efficacy and tolerability of Q8003 vs oxycodone or morphine for moderate-to-severe postoperative pain following bunionectomy surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind M | 2013 |
Postoperative fentanyl patch versus subacromial bupivacaine infusion in arthroscopic shoulder surgery.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Arthroscopy; Bupiva | 2013 |
Randomized comparison between the combination of acetaminophen and ibuprofen and each constituent alone for analgesia following tonsillectomy in children.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; | 2013 |
Evaluation of etoricoxib in patients undergoing total knee replacement surgery in a double-blind, randomized controlled trial.
Topics: Aged; Arthroplasty, Replacement, Knee; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Etoricoxib; | 2013 |
Comparison between prescription of regular or on-demand ibuprofen on postoperative pain after single-visit root canal treatment of teeth with irreversible pulpitis.
Topics: Adult; Analgesia, Patient-Controlled; Anti-Inflammatory Agents, Non-Steroidal; Bismuth; Epoxy Resins | 2014 |
A multicenter, randomized, double-blind placebo-controlled, single dose trial of the safety and efficacy of intravenous ibuprofen for treatment of pain in pediatric patients undergoing tonsillectomy.
Topics: Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; Double-Blind Method; | 2014 |
Multimodal analgesia versus traditional opiate based analgesia after cardiac surgery, a randomized controlled trial.
Topics: Acetaminophen; Aged; Amines; Analgesia; Analgesics; Analgesics, Opioid; Cardiac Surgical Procedures; | 2014 |
Does the dimension of the graft influence patient morbidity and root coverage outcomes? A randomized controlled clinical trial.
Topics: Alveolar Process; Analgesics, Non-Narcotic; Double-Blind Method; Esthetics, Dental; Follow-Up Studie | 2014 |
Does the dimension of the graft influence patient morbidity and root coverage outcomes? A randomized controlled clinical trial.
Topics: Alveolar Process; Analgesics, Non-Narcotic; Double-Blind Method; Esthetics, Dental; Follow-Up Studie | 2014 |
Does the dimension of the graft influence patient morbidity and root coverage outcomes? A randomized controlled clinical trial.
Topics: Alveolar Process; Analgesics, Non-Narcotic; Double-Blind Method; Esthetics, Dental; Follow-Up Studie | 2014 |
Does the dimension of the graft influence patient morbidity and root coverage outcomes? A randomized controlled clinical trial.
Topics: Alveolar Process; Analgesics, Non-Narcotic; Double-Blind Method; Esthetics, Dental; Follow-Up Studie | 2014 |
Dexamethasone for pain after outpatient shoulder surgery: a randomised, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Acromioclavicular Joint; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; | 2014 |
Dexamethasone for pain after outpatient shoulder surgery: a randomised, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Acromioclavicular Joint; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; | 2014 |
Dexamethasone for pain after outpatient shoulder surgery: a randomised, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Acromioclavicular Joint; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; | 2014 |
Dexamethasone for pain after outpatient shoulder surgery: a randomised, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Acromioclavicular Joint; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; | 2014 |
Validating speed of onset as a key component of good analgesic response in acute pain.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; | 2015 |
Continuous wound infiltration with ropivacaine for analgesia after caesarean section: a randomised, placebo-controlled trial.
Topics: Abdominal Injuries; Acetaminophen; Adult; Amides; Analgesia; Anesthesia, Obstetrical; Anesthesia, Sp | 2014 |
Onset of analgesia and efficacy of ibuprofen sodium in postsurgical dental pain: a randomized, placebo-controlled study versus standard ibuprofen.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Male; P | 2015 |
The shortened infusion time of intravenous ibuprofen, part 2: a multicenter, open-label, surgical surveillance trial to evaluate safety.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug | 2015 |
The shortened infusion time of intravenous ibuprofen, part 2: a multicenter, open-label, surgical surveillance trial to evaluate safety.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug | 2015 |
The shortened infusion time of intravenous ibuprofen, part 2: a multicenter, open-label, surgical surveillance trial to evaluate safety.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug | 2015 |
The shortened infusion time of intravenous ibuprofen, part 2: a multicenter, open-label, surgical surveillance trial to evaluate safety.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Combination paracetamol and ibuprofen for pain relief after oral surgery: a dose ranging study.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Double | 2015 |
Cerebral analgesic response to nonsteroidal anti-inflammatory drug ibuprofen.
Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cerebrovascular Circulation; Doub | 2015 |
Preoperative dexamethasone reduces acute but not sustained pain after lumbar disk surgery: a randomized, blinded, placebo-controlled trial.
Topics: Acetaminophen; Acute Pain; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammato | 2015 |
A new analgesia regimen after (adeno) tonsillectomy in children: a pilot study.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Child; Child, Preschool; Drug Therapy, Combination; Female | 2016 |
Comparison of the Incidence of Postoperative Pain after Using 2 Reciprocating Systems and a Continuous Rotary System: A Prospective Randomized Clinical Trial.
Topics: Adult; Aged; Analgesics; Female; Humans; Ibuprofen; Incidence; Male; Middle Aged; Pain, Postoperativ | 2016 |
Comparison of the Incidence of Postoperative Pain after Using 2 Reciprocating Systems and a Continuous Rotary System: A Prospective Randomized Clinical Trial.
Topics: Adult; Aged; Analgesics; Female; Humans; Ibuprofen; Incidence; Male; Middle Aged; Pain, Postoperativ | 2016 |
Comparison of the Incidence of Postoperative Pain after Using 2 Reciprocating Systems and a Continuous Rotary System: A Prospective Randomized Clinical Trial.
Topics: Adult; Aged; Analgesics; Female; Humans; Ibuprofen; Incidence; Male; Middle Aged; Pain, Postoperativ | 2016 |
Comparison of the Incidence of Postoperative Pain after Using 2 Reciprocating Systems and a Continuous Rotary System: A Prospective Randomized Clinical Trial.
Topics: Adult; Aged; Analgesics; Female; Humans; Ibuprofen; Incidence; Male; Middle Aged; Pain, Postoperativ | 2016 |
Comparison of the Incidence of Postoperative Pain after Using 2 Reciprocating Systems and a Continuous Rotary System: A Prospective Randomized Clinical Trial.
Topics: Adult; Aged; Analgesics; Female; Humans; Ibuprofen; Incidence; Male; Middle Aged; Pain, Postoperativ | 2016 |
Comparison of the Incidence of Postoperative Pain after Using 2 Reciprocating Systems and a Continuous Rotary System: A Prospective Randomized Clinical Trial.
Topics: Adult; Aged; Analgesics; Female; Humans; Ibuprofen; Incidence; Male; Middle Aged; Pain, Postoperativ | 2016 |
Comparison of the Incidence of Postoperative Pain after Using 2 Reciprocating Systems and a Continuous Rotary System: A Prospective Randomized Clinical Trial.
Topics: Adult; Aged; Analgesics; Female; Humans; Ibuprofen; Incidence; Male; Middle Aged; Pain, Postoperativ | 2016 |
Comparison of the Incidence of Postoperative Pain after Using 2 Reciprocating Systems and a Continuous Rotary System: A Prospective Randomized Clinical Trial.
Topics: Adult; Aged; Analgesics; Female; Humans; Ibuprofen; Incidence; Male; Middle Aged; Pain, Postoperativ | 2016 |
Comparison of the Incidence of Postoperative Pain after Using 2 Reciprocating Systems and a Continuous Rotary System: A Prospective Randomized Clinical Trial.
Topics: Adult; Aged; Analgesics; Female; Humans; Ibuprofen; Incidence; Male; Middle Aged; Pain, Postoperativ | 2016 |
What is the Effect of No Endodontic Debridement on Postoperative Pain for Symptomatic Teeth with Pulpal Necrosis?
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Debridement | 2016 |
Role of Prophylactic Antibiotics in the Management of Postoperative Endodontic Pain.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Endodontics; Hu | 2015 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Intravenous Ibuprofen for Treatment of Post-Operative Pain: A Multicenter, Double Blind, Placebo-Controlled, Randomized Clinical Trial.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Ibuprofen; Infusions, Intravenous; Male; Middle Ag | 2016 |
Intravenous Ibuprofen for Treatment of Post-Operative Pain: A Multicenter, Double Blind, Placebo-Controlled, Randomized Clinical Trial.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Ibuprofen; Infusions, Intravenous; Male; Middle Ag | 2016 |
Intravenous Ibuprofen for Treatment of Post-Operative Pain: A Multicenter, Double Blind, Placebo-Controlled, Randomized Clinical Trial.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Ibuprofen; Infusions, Intravenous; Male; Middle Ag | 2016 |
Intravenous Ibuprofen for Treatment of Post-Operative Pain: A Multicenter, Double Blind, Placebo-Controlled, Randomized Clinical Trial.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Ibuprofen; Infusions, Intravenous; Male; Middle Ag | 2016 |
Comparative Assessment of the Effect of Ibuprofen and Etodolac on Edema, Trismus, and Pain in Lower Third Molar Surgery: A Randomized Clinical Trial.
Topics: Adolescent; Cyclooxygenase 2 Inhibitors; Edema; Etodolac; Female; Humans; Ibuprofen; Male; Mandible; | 2016 |
Effect of continuous ultrasonic irrigation on postoperative pain in mandibular molars with nonvital pulps: a randomized clinical trial.
Topics: Adult; Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Male; Molar; Pain Measurement; Pain, Pos | 2017 |
Effect of continuous ultrasonic irrigation on postoperative pain in mandibular molars with nonvital pulps: a randomized clinical trial.
Topics: Adult; Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Male; Molar; Pain Measurement; Pain, Pos | 2017 |
Effect of continuous ultrasonic irrigation on postoperative pain in mandibular molars with nonvital pulps: a randomized clinical trial.
Topics: Adult; Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Male; Molar; Pain Measurement; Pain, Pos | 2017 |
Effect of continuous ultrasonic irrigation on postoperative pain in mandibular molars with nonvital pulps: a randomized clinical trial.
Topics: Adult; Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Male; Molar; Pain Measurement; Pain, Pos | 2017 |
Effect of continuous ultrasonic irrigation on postoperative pain in mandibular molars with nonvital pulps: a randomized clinical trial.
Topics: Adult; Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Male; Molar; Pain Measurement; Pain, Pos | 2017 |
Effect of continuous ultrasonic irrigation on postoperative pain in mandibular molars with nonvital pulps: a randomized clinical trial.
Topics: Adult; Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Male; Molar; Pain Measurement; Pain, Pos | 2017 |
Effect of continuous ultrasonic irrigation on postoperative pain in mandibular molars with nonvital pulps: a randomized clinical trial.
Topics: Adult; Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Male; Molar; Pain Measurement; Pain, Pos | 2017 |
Effect of continuous ultrasonic irrigation on postoperative pain in mandibular molars with nonvital pulps: a randomized clinical trial.
Topics: Adult; Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Male; Molar; Pain Measurement; Pain, Pos | 2017 |
Effect of continuous ultrasonic irrigation on postoperative pain in mandibular molars with nonvital pulps: a randomized clinical trial.
Topics: Adult; Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Male; Molar; Pain Measurement; Pain, Pos | 2017 |
Synergistic Effect of Intravenous Ibuprofen and Hydromorphone for Postoperative Pain: Prospective Randomized Controlled Trial.
Topics: Adult; Analgesics, Opioid; Breast; Double-Blind Method; Female; Humans; Hydromorphone; Ibuprofen; Mi | 2016 |
A Randomized Trial Comparing the Safety and Efficacy of Intravenous Ibuprofen versus Ibuprofen and Acetaminophen in Knee or Hip Arthroplasty.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacement, | 2016 |
Transversus abdominis plane block after laparoscopic colonic resection in cancer patients: A randomised clinical trial.
Topics: Abdominal Muscles; Acetaminophen; Aged; Colectomy; Colonic Neoplasms; Denmark; Double-Blind Method; | 2016 |
Comparison Between Dexamethasone and Ibuprofen for Postoperative Pain Prevention and Control After Surgical Implant Placement: A Double-Masked, Parallel-Group, Placebo-Controlled Randomized Clinical Trial.
Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Dental Implantation, En | 2017 |
Influence of high-dose intraoperative remifentanil with intravenous ibuprofen on postoperative morphine consumption in patients undergoing pancreaticoduodenectomy: a randomized trial.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Cyclooxygenase Inhibitors; Female; Humans; | 2016 |
PANSAID - PAracetamol and NSAID in combination: study protocol for a randomised trial.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Clinical Protocols; Drug Therapy, Combinatio | 2017 |
PANSAID - PAracetamol and NSAID in combination: study protocol for a randomised trial.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Clinical Protocols; Drug Therapy, Combinatio | 2017 |
PANSAID - PAracetamol and NSAID in combination: study protocol for a randomised trial.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Clinical Protocols; Drug Therapy, Combinatio | 2017 |
PANSAID - PAracetamol and NSAID in combination: study protocol for a randomised trial.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Clinical Protocols; Drug Therapy, Combinatio | 2017 |
Effects of single-dose preemptive intravenous ibuprofen on postoperative opioid consumption and acute pain after laparoscopic cholecystectomy.
Topics: Administration, Intravenous; Adolescent; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, | 2017 |
Comparison of paracetamol, ibuprofen, and diclofenac potassium for pain relief following dental extractions and deep cavity preparations.
Topics: Acetaminophen; Adult; Anesthesia, Local; Anti-Inflammatory Agents, Non-Steroidal; Dental Cavity Prep | 2017 |
Randomized, double-blinded, placebo-controlled trial comparing two multimodal opioid-minimizing pain management regimens following transsphenoidal surgery.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic | 2018 |
Randomized, double-blinded, placebo-controlled trial comparing two multimodal opioid-minimizing pain management regimens following transsphenoidal surgery.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic | 2018 |
Randomized, double-blinded, placebo-controlled trial comparing two multimodal opioid-minimizing pain management regimens following transsphenoidal surgery.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic | 2018 |
Randomized, double-blinded, placebo-controlled trial comparing two multimodal opioid-minimizing pain management regimens following transsphenoidal surgery.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic | 2018 |
Ibuprofen versus acetaminophen for the relief of perineal pain after childbirth: a randomized controlled trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Episiotomy; | 2008 |
Single dose analgesic efficacy of tapentadol in postsurgical dental pain: the results of a randomized, double-blind, placebo-controlled study.
Topics: Adult; Analgesics; Double-Blind Method; Female; Humans; Ibuprofen; Male; Morphine; Pain, Postoperati | 2008 |
Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial.
Topics: Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; C | 2008 |
Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial.
Topics: Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; C | 2008 |
Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial.
Topics: Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; C | 2008 |
Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial.
Topics: Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; C | 2008 |
A randomized, double-blind, placebo-controlled study comparing the efficacy and safety of paracetamol, serratiopeptidase, ibuprofen and betamethasone using the dental impaction pain model.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory | 2009 |
Onset of analgesia with sodium ibuprofen, ibuprofen acid incorporating poloxamer and acetaminophen--a single-dose, double-blind, placebo-controlled study in patients with post-operative dental pain.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen | 2009 |
Routine packing of simple cutaneous abscesses is painful and probably unnecessary.
Topics: Abscess; Analgesics, Non-Narcotic; Anti-Infective Agents; Drainage; Emergency Service, Hospital; Fem | 2009 |
Routine packing of simple cutaneous abscesses is painful and probably unnecessary.
Topics: Abscess; Analgesics, Non-Narcotic; Anti-Infective Agents; Drainage; Emergency Service, Hospital; Fem | 2009 |
Routine packing of simple cutaneous abscesses is painful and probably unnecessary.
Topics: Abscess; Analgesics, Non-Narcotic; Anti-Infective Agents; Drainage; Emergency Service, Hospital; Fem | 2009 |
Routine packing of simple cutaneous abscesses is painful and probably unnecessary.
Topics: Abscess; Analgesics, Non-Narcotic; Anti-Infective Agents; Drainage; Emergency Service, Hospital; Fem | 2009 |
Routine packing of simple cutaneous abscesses is painful and probably unnecessary.
Topics: Abscess; Analgesics, Non-Narcotic; Anti-Infective Agents; Drainage; Emergency Service, Hospital; Fem | 2009 |
Routine packing of simple cutaneous abscesses is painful and probably unnecessary.
Topics: Abscess; Analgesics, Non-Narcotic; Anti-Infective Agents; Drainage; Emergency Service, Hospital; Fem | 2009 |
Routine packing of simple cutaneous abscesses is painful and probably unnecessary.
Topics: Abscess; Analgesics, Non-Narcotic; Anti-Infective Agents; Drainage; Emergency Service, Hospital; Fem | 2009 |
Routine packing of simple cutaneous abscesses is painful and probably unnecessary.
Topics: Abscess; Analgesics, Non-Narcotic; Anti-Infective Agents; Drainage; Emergency Service, Hospital; Fem | 2009 |
Routine packing of simple cutaneous abscesses is painful and probably unnecessary.
Topics: Abscess; Analgesics, Non-Narcotic; Anti-Infective Agents; Drainage; Emergency Service, Hospital; Fem | 2009 |
Routine packing of simple cutaneous abscesses is painful and probably unnecessary.
Topics: Abscess; Analgesics, Non-Narcotic; Anti-Infective Agents; Drainage; Emergency Service, Hospital; Fem | 2009 |
Routine packing of simple cutaneous abscesses is painful and probably unnecessary.
Topics: Abscess; Analgesics, Non-Narcotic; Anti-Infective Agents; Drainage; Emergency Service, Hospital; Fem | 2009 |
Routine packing of simple cutaneous abscesses is painful and probably unnecessary.
Topics: Abscess; Analgesics, Non-Narcotic; Anti-Infective Agents; Drainage; Emergency Service, Hospital; Fem | 2009 |
Routine packing of simple cutaneous abscesses is painful and probably unnecessary.
Topics: Abscess; Analgesics, Non-Narcotic; Anti-Infective Agents; Drainage; Emergency Service, Hospital; Fem | 2009 |
Routine packing of simple cutaneous abscesses is painful and probably unnecessary.
Topics: Abscess; Analgesics, Non-Narcotic; Anti-Infective Agents; Drainage; Emergency Service, Hospital; Fem | 2009 |
Routine packing of simple cutaneous abscesses is painful and probably unnecessary.
Topics: Abscess; Analgesics, Non-Narcotic; Anti-Infective Agents; Drainage; Emergency Service, Hospital; Fem | 2009 |
Routine packing of simple cutaneous abscesses is painful and probably unnecessary.
Topics: Abscess; Analgesics, Non-Narcotic; Anti-Infective Agents; Drainage; Emergency Service, Hospital; Fem | 2009 |
Effects of combination treatment with ketoprofen 100 mg + acetaminophen 1000 mg on postoperative dental pain: a single-dose, 10-hour, randomized, double-blind, active- and placebo-controlled clinical trial.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non- | 2009 |
The efficacy of acetaminophen-caffeine compared to Ibuprofen in the control of postoperative pain after periodontal surgery: a crossover pilot study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; C | 2009 |
Comparison of ibuprofen and acetaminophen with codeine following cosmetic facial surgery.
Topics: Acetaminophen; Analgesics; Codeine; Double-Blind Method; Drug Therapy, Combination; Face; Humans; Ib | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
A multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative pain.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents | 2009 |
Postoperative pain relief after surgical removal of impacted third molars: a single-blind, randomized, controlled study to compare levobupivacaine and mepivacaine.
Topics: Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Bupiva | 2009 |
The effect of a single dose of bupivacaine on donor site pain after anterior iliac crest bone harvesting.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Alveolar Ridge Augmentation; Analgesics, Non-Narcotic | 2010 |
Maxillary infiltration anaesthesia by ropivacaine for upper third molar surgery.
Topics: Adult; Amides; Analgesics, Non-Narcotic; Anesthesia, Dental; Anesthetics, Local; Arteries; Blood Pre | 2010 |
Combined acetaminophen and ibuprofen for pain relief after oral surgery in adults: a randomized controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Drug Combinations; Female; Humans; Ibupr | 2010 |
Combined acetaminophen and ibuprofen for pain relief after oral surgery in adults: a randomized controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Drug Combinations; Female; Humans; Ibupr | 2010 |
Combined acetaminophen and ibuprofen for pain relief after oral surgery in adults: a randomized controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Drug Combinations; Female; Humans; Ibupr | 2010 |
Combined acetaminophen and ibuprofen for pain relief after oral surgery in adults: a randomized controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Drug Combinations; Female; Humans; Ibupr | 2010 |
Antibiotic prophylaxis in third molar surgery: A randomized double-blind placebo-controlled clinical trial using split-mouth technique.
Topics: Acetaminophen; Adult; Amoxicillin; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Bacterial Agen | 2010 |
Pain after surgery: can protective analgesia reduce pain? A randomised clinical trial.
Topics: Adult; Analgesics, Non-Narcotic; Cohort Studies; Delayed-Action Preparations; Double-Blind Method; D | 2010 |
Pre-emptive ibuprofen arginate in third molar surgery: a double-blind randomized controlled crossover clinical trial.
Topics: Adult; Analgesics, Non-Narcotic; Arginine; Cross-Over Studies; Double-Blind Method; Drug Combination | 2009 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A multi-center, randomized, double-blind placebo-controlled trial of intravenous-ibuprofen (IV-ibuprofen) for treatment of pain in post-operative orthopedic adult patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Doub | 2010 |
A single-tablet fixed-dose combination of racemic ibuprofen/paracetamol in the management of moderate to severe postoperative dental pain in adult and adolescent patients: a multicenter, two-stage, randomized, double-blind, parallel-group, placebo-control
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Tes | 2010 |
Comparison of the analgesic efficacy of concurrent ibuprofen and paracetamol with ibuprofen or paracetamol alone in the management of moderate to severe acute postoperative dental pain in adolescents and adults: a randomized, double-blind, placebo-control
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, | 2010 |
Efficacy of ibuprofen versus lornoxicam after third molar surgery: a randomized, double-blind, crossover pilot study.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Double-Blind Method; | 2011 |
The effects of oral ibuprofen and celecoxib in preventing pain, improving recovery outcomes and patient satisfaction after ambulatory surgery.
Topics: Activities of Daily Living; Administration, Oral; Adult; Ambulatory Surgical Procedures; Analgesics, | 2011 |
Evaluation of the dose range of etoricoxib in an acute pain setting using the postoperative dental pain model.
Topics: Acetaminophen; Adolescent; Adult; Anesthesia, Dental; Anti-Inflammatory Agents, Non-Steroidal; Codei | 2011 |
The use of a non-benzodiazepine hypnotic sleep-aid (Zolpidem) in patients undergoing ACL reconstruction: a randomized controlled clinical trial.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Analysis of Variance; Anterior Cruciate Ligament; Anti-Inf | 2011 |
A randomised, five-parallel-group, placebo-controlled trial comparing the efficacy and tolerability of analgesic combinations including a novel single-tablet combination of ibuprofen/paracetamol for postoperative dental pain.
Topics: Acetaminophen; Adolescent; Analgesics; Dent Disease; Double-Blind Method; Drug Therapy, Combination; | 2011 |
Modeling the onset and offset of dental pain relief by ibuprofen.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind M | 2012 |
Comparison of pre-emptive ibuprofen, paracetamol, and placebo administration in reducing post-operative pain in primary tooth extraction.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; | 2011 |
A randomized, controlled study to investigate the analgesic efficacy of single doses of the cannabinoid receptor-2 agonist GW842166, ibuprofen or placebo in patients with acute pain following third molar tooth extraction.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Double-Blind Method; | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
Effectiveness of tenoxicam and ibuprofen for pain prevention following endodontic therapy in comparison to placebo: a randomized double-blind clinical trial.
Topics: Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Ste | 2011 |
Explaining the acetaminophen-ibuprofen analgesic interaction using a response surface model.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Child; Computer Simulation; Dose-Response Relationsh | 2011 |
Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid | 2012 |
Efficacy of Ibuprofen and ibuprofen/acetaminophen on postoperative pain in symptomatic patients with a pulpal diagnosis of necrosis.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 2011 |
Analgesic efficacy with rapidly absorbed ibuprofen sodium dihydrate in postsurgical dental pain: results from the randomized QUIKK trial.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Cross-Over Studies; Double-Blind Method; Female; Humans | 2011 |
The effect of orally administered ketamine on requirement for anesthetics and postoperative pain in mandibular molar teeth with irreversible pulpitis.
Topics: Adjuvants, Anesthesia; Administration, Oral; Adolescent; Adult; Analgesics; Anesthesia, Dental; Anes | 2011 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Preemptive analgesic effect of low doses of celecoxib is superior to low doses of traditional nonsteroidal anti-inflammatory drugs.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; C | 2012 |
A comparative study of oral tramadol and ibuprofen in postoperative pain in operations of lower abdomen.
Topics: Administration, Oral; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; Hu | 2011 |
Effect of preoperative ibuprofen on pain and swelling after lower third molar removal: a randomized controlled trial.
Topics: Adult; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Edema; Female; | 2012 |
The effect of an 810-nm diode laser on postoperative pain and tissue response after modified Widman flap surgery: a pilot study in humans.
Topics: Analgesics, Non-Narcotic; Chronic Periodontitis; Color; Combined Modality Therapy; Edema; Female; Hu | 2013 |
A randomized, controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine (Tylenol 3) after outpatient breast surgery.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Breast Neoplasms; Ca | 2012 |
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E | 2012 |
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E | 2012 |
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E | 2012 |
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E | 2012 |
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E | 2012 |
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E | 2012 |
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E | 2012 |
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E | 2012 |
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; E | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Assessment of preemptive analgesia with ibuprofen coadministered or not with dexamethasone in third molar surgery: a randomized double-blind controlled clinical trial.
Topics: Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Dexamethasone; Double-Blind Method; | 2013 |
Assessment of preemptive analgesia with ibuprofen coadministered or not with dexamethasone in third molar surgery: a randomized double-blind controlled clinical trial.
Topics: Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Dexamethasone; Double-Blind Method; | 2013 |
Assessment of preemptive analgesia with ibuprofen coadministered or not with dexamethasone in third molar surgery: a randomized double-blind controlled clinical trial.
Topics: Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Dexamethasone; Double-Blind Method; | 2013 |
Assessment of preemptive analgesia with ibuprofen coadministered or not with dexamethasone in third molar surgery: a randomized double-blind controlled clinical trial.
Topics: Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Dexamethasone; Double-Blind Method; | 2013 |
Effect of occlusal reduction on postoperative pain in teeth with irreversible pulpitis and mild tenderness to percussion.
Topics: Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Calcium Hydroxide; Dental | 2013 |
Postoperative pain after foraminal enlargement in anterior teeth with necrosis and apical periodontitis: a prospective and randomized clinical trial.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Asymptomatic Diseases; Dental Pulp Cavity; Dental Pu | 2013 |
Paracetamol versus paracetamol-codeine in the treatment of post-operative dental pain: a randomized, double-blind, prospective trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 2002 |
In vivo selectivity of a selective cyclooxygenase 2 inhibitor in the oral surgery model.
Topics: Adult; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinopros | 2002 |
A controlled comparative study of ibuprofen arginate versus conventional ibuprofen in the treatment of postoperative dental pain.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Arginine; Dose-Response Relationship, Drug; Drug Combin | 2002 |
Efficacy and tolerability of nonprescription ibuprofen versus celecoxib for dental pain.
Topics: Adolescent; Adult; Celecoxib; Dosage Forms; Double-Blind Method; Drug Administration Schedule; Femal | 2002 |
A randomized, double-blind, placebo-controlled comparison of the analgesic efficacy, onset of action, and tolerability of ibuprofen arginate and ibuprofen in postoperative dental pain.
Topics: Adult; Analgesics, Non-Narcotic; Arginine; Dose-Response Relationship, Drug; Double-Blind Method; Dr | 2002 |
Ibuprofen arginate provides effective relief from postoperative dental pain with a more rapid onset of action than ibuprofen.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Double-Blind Method; Drug Combinations; Fe | 2002 |
A comparison of rofecoxib versus celecoxib in treating pain after dental surgery: a single-center, randomized, double-blind, placebo- and active-comparator-controlled, parallel-group, single-dose study using the dental impaction pain model.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitor | 2002 |
Effectiveness of prophylactic use of rofecoxib in comparison with ibuprofen on postendodontic pain.
Topics: Acute Disease; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase | 2003 |
A randomized, double-blind crossover trial of paracetamol 1000 mg four times daily vs ibuprofen 600 mg: effect on swelling and other postoperative events after third molar surgery.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies | 2003 |
Severity of baseline pain and degree of analgesia in the third molar post-extraction dental pain model.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Ibuprofen; Male | 2003 |
Analgesic efficacy of rectal acetaminophen and ibuprofen alone or in combination for paediatric day-case adenoidectomy.
Topics: Acetaminophen; Adenoidectomy; Administration, Rectal; Ambulatory Surgical Procedures; Analgesics, No | 2003 |
Evaluation of postoperative bupivacaine infusion for pain management after anterior cruciate ligament reconstruction.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior Cruciate Li | 2003 |
Efficacy of scheduled nonnarcotic analgesic medications in children after suboccipital craniectomy.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Arnold-Chiari Malformation; Child; Child, Preschool; C | 2004 |
Analgesia and discharge following preincisional ilioinguinal and iliohypogastric nerve block combined with general or spinal anaesthesia for inguinal herniorrhaphy.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Analgesia; Analgesics, Opioid; Anesthesia, General; Ane | 2004 |
Analgesia and discharge following preincisional ilioinguinal and iliohypogastric nerve block combined with general or spinal anaesthesia for inguinal herniorrhaphy.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Analgesia; Analgesics, Opioid; Anesthesia, General; Ane | 2004 |
Analgesia and discharge following preincisional ilioinguinal and iliohypogastric nerve block combined with general or spinal anaesthesia for inguinal herniorrhaphy.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Analgesia; Analgesics, Opioid; Anesthesia, General; Ane | 2004 |
Analgesia and discharge following preincisional ilioinguinal and iliohypogastric nerve block combined with general or spinal anaesthesia for inguinal herniorrhaphy.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Analgesia; Analgesics, Opioid; Anesthesia, General; Ane | 2004 |
Spinal prostaglandin formation and pain perception following thoracotomy: a role for cyclooxygenase-2.
Topics: 6-Ketoprostaglandin F1 alpha; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibito | 2004 |
Sedation with midazolam leads to reduced pain after dental surgery.
Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Endpoint Determination; Female; Humans; | 2004 |
Analgesic efficacy of single oral doses of lumiracoxib and ibuprofen in patients with postoperative dental pain.
Topics: Adolescent; Adult; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Female; Humans; Ibupr | 2004 |
A double-blind randomised controlled clinical trial of the effect of preoperative ibuprofen, diclofenac, paracetamol with codeine and placebo tablets for relief of postoperative pain after removal of impacted third molars.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Ascorbic Acid; Codeine; Diclofenac; Double-Blind | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
Ibuprofen vs. acetaminophen vs. ibuprofen and acetaminophen after arthroscopically assisted anterior cruciate ligament reconstruction.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthesia, General; Anterior Cruciate Ligament; Ant | 2004 |
Efficacy of ibuprofen-hydrocodone for the treatment of postoperative pain after periodontal surgery.
Topics: Adult; Aged; Analgesics, Opioid; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cros | 2004 |
Onset of analgesia and analgesic efficacy of tramadol/acetaminophen and codeine/acetaminophen/ibuprofen in acute postoperative pain: a single-center, single-dose, randomized, active-controlled, parallel-group study in a dental surgery pain model.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Opioid; Codeine; Drug Combinations; Female; | 2004 |
Thermachoice endometrial ablation in the outpatient setting, without local anesthesia or intravenous sedation: a prospective cohort study.
Topics: Adult; Analgesics, Non-Narcotic; Anesthesia, Local; Catheter Ablation; Conscious Sedation; Endometri | 2005 |
Combination oxycodone 5 mg/ibuprofen 400 mg for the treatment of pain after abdominal or pelvic surgery in women: a randomized, double-blind, placebo- and active-controlled parallel-group study.
Topics: Abdomen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Combin | 2005 |
Combination oxycodone 5 mg/ibuprofen 400 mg for the treatment of pain after abdominal or pelvic surgery in women: a randomized, double-blind, placebo- and active-controlled parallel-group study.
Topics: Abdomen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Combin | 2005 |
Combination oxycodone 5 mg/ibuprofen 400 mg for the treatment of pain after abdominal or pelvic surgery in women: a randomized, double-blind, placebo- and active-controlled parallel-group study.
Topics: Abdomen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Combin | 2005 |
Combination oxycodone 5 mg/ibuprofen 400 mg for the treatment of pain after abdominal or pelvic surgery in women: a randomized, double-blind, placebo- and active-controlled parallel-group study.
Topics: Abdomen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Combin | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study.
Topics: Acupuncture Analgesia; Acupuncture, Ear; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthrop | 2005 |
Combination oxycodone 5 mg/ibuprofen 400 mg for the treatment of postoperative pain: a double-blind, placebo- and active-controlled parallel-group study.
Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Double-Blind M | 2004 |
Pharmacokinetic properties of combination oxycodone plus racemic ibuprofen: two randomized, open-label, crossover studies in healthy adult volunteers.
Topics: Administration, Oral; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Area Under | 2004 |
Efficacy of preoperative oral rofecoxib in pain control for third molar surgery.
Topics: Administration, Oral; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cross-Ov | 2005 |
Analgesic efficacy and tolerability of oxycodone 5 mg/ibuprofen 400 mg compared with those of oxycodone 5 mg/acetaminophen 325 mg and hydrocodone 7.5 mg/acetaminophen 500 mg in patients with moderate to severe postoperative pain: a randomized, double-blin
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 2005 |
Postoperative epidural morphine for postpartum tubal ligation analgesia.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesic | 2005 |
[Randomized controlled study of S (+) -ismer of ibuprofen supporsitory].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Fever; Humans; Ibuprofen; | 2004 |
COX-2 inhibitors and pain after oral surgery - pertinent papers 2002-2003.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitor | 2006 |
Effects of preoperative ibuprofen and naproxen sodium on orthodontic pain.
Topics: Adolescent; Analgesics, Non-Narcotic; Analysis of Variance; Dose-Response Relationship, Drug; Facial | 2005 |
Effects of preoperative ibuprofen and naproxen sodium on orthodontic pain.
Topics: Adolescent; Analgesics, Non-Narcotic; Analysis of Variance; Dose-Response Relationship, Drug; Facial | 2005 |
Effects of preoperative ibuprofen and naproxen sodium on orthodontic pain.
Topics: Adolescent; Analgesics, Non-Narcotic; Analysis of Variance; Dose-Response Relationship, Drug; Facial | 2005 |
Effects of preoperative ibuprofen and naproxen sodium on orthodontic pain.
Topics: Adolescent; Analgesics, Non-Narcotic; Analysis of Variance; Dose-Response Relationship, Drug; Facial | 2005 |
Evaluation of the clinical behaviour of a polyvinylpyrrolidone and sodium hyalonurate gel (Gelclair) in patients subjected to surgical treatment with CO2 laser.
Topics: Administration, Oral; Administration, Topical; Adult; Analgesics, Non-Narcotic; Carbon Dioxide; Degl | 2006 |
Comparison of adjunctive use of rofecoxib versus ibuprofen in the management of postoperative pain after uterine artery embolization.
Topics: Adult; Aged; Chi-Square Distribution; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Embolization | 2006 |
Genetically mediated interindividual variation in analgesic responses to cyclooxygenase inhibitory drugs.
Topics: Adolescent; Adult; Aged; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Hapl | 2006 |
Safety and efficacy of routine postoperative ibuprofen for pain and disability related to ectopic bone formation after hip replacement surgery (HIPAID): randomised controlled trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Australia; Double-Blind Met | 2006 |
Combining paracetamol with a selective cyclooxygenase-2 inhibitor for acute pain relief after third molar surgery: a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Cohort Studies; Cyclooxygenase 2 Inhibitors; Double- | 2006 |
Preincisional paravertebral block reduces the prevalence of chronic pain after breast surgery.
Topics: Acetaminophen; Analgesia, Epidural; Breast Neoplasms; Bupivacaine; Codeine; Follow-Up Studies; Human | 2006 |
Preincisional paravertebral block reduces the prevalence of chronic pain after breast surgery.
Topics: Acetaminophen; Analgesia, Epidural; Breast Neoplasms; Bupivacaine; Codeine; Follow-Up Studies; Human | 2006 |
Preincisional paravertebral block reduces the prevalence of chronic pain after breast surgery.
Topics: Acetaminophen; Analgesia, Epidural; Breast Neoplasms; Bupivacaine; Codeine; Follow-Up Studies; Human | 2006 |
Preincisional paravertebral block reduces the prevalence of chronic pain after breast surgery.
Topics: Acetaminophen; Analgesia, Epidural; Breast Neoplasms; Bupivacaine; Codeine; Follow-Up Studies; Human | 2006 |
Ibuprofen as a pre-emptive analgesic is as effective as rofecoxib for mandibular third molar surgery.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygena | 2006 |
Randomized controlled trial comparing Thermachoice III* in the outpatient versus daycase setting.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, General; Catheter Ablation; Catheterization; Endo | 2007 |
Intravenous acetaminophen vs oral ibuprofen in combination with morphine PCIA after Cesarean delivery.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; A | 2006 |
Attenuation of C-reactive protein increases after exodontia by tramadol and ibuprofen.
Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; C-Reactive Protein; Drug Combina | 2006 |
Auricular acupuncture for pain relief after ambulatory knee surgery: a randomized trial.
Topics: Acupuncture, Ear; Adult; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Arthro | 2007 |
Auricular acupuncture for pain relief after ambulatory knee surgery: a randomized trial.
Topics: Acupuncture, Ear; Adult; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Arthro | 2007 |
Auricular acupuncture for pain relief after ambulatory knee surgery: a randomized trial.
Topics: Acupuncture, Ear; Adult; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Arthro | 2007 |
Auricular acupuncture for pain relief after ambulatory knee surgery: a randomized trial.
Topics: Acupuncture, Ear; Adult; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Arthro | 2007 |
Auricular acupuncture for pain relief after ambulatory knee surgery: a randomized trial.
Topics: Acupuncture, Ear; Adult; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Arthro | 2007 |
Auricular acupuncture for pain relief after ambulatory knee surgery: a randomized trial.
Topics: Acupuncture, Ear; Adult; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Arthro | 2007 |
Auricular acupuncture for pain relief after ambulatory knee surgery: a randomized trial.
Topics: Acupuncture, Ear; Adult; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Arthro | 2007 |
Auricular acupuncture for pain relief after ambulatory knee surgery: a randomized trial.
Topics: Acupuncture, Ear; Adult; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Arthro | 2007 |
Auricular acupuncture for pain relief after ambulatory knee surgery: a randomized trial.
Topics: Acupuncture, Ear; Adult; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Arthro | 2007 |
Ibuprofen sodium dihydrate, an ibuprofen formulation with improved absorption characteristics, provides faster and greater pain relief than ibuprofen acid.
Topics: Absorption; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Ibu | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
Assessment of early postoperative pain and haemorrhage in young children undergoing dental extractions under general anaesthesia.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, | 2007 |
Cerebrospinal fluid distribution of ibuprofen after intravenous administration in children.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Female; Humans; Ibuprofen; Infant; | 2007 |
Millimetre wave therapy for pain relief after total knee arthroplasty: a randomised controlled trial.
Topics: Aged; Analgesia; Analgesia, Patient-Controlled; Anti-Inflammatory Agents, Non-Steroidal; Arthroplast | 2008 |
Continuous infraclavicular brachial plexus block: a modified technique to better secure catheter position in infants and children.
Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Brachial Plexus; Bupivacaine; Catheteri | 2008 |
A randomized controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine after outpatient general surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics; Caffeine; Centra | 2008 |
A randomized controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine after outpatient general surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics; Caffeine; Centra | 2008 |
A randomized controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine after outpatient general surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics; Caffeine; Centra | 2008 |
A randomized controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine after outpatient general surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics; Caffeine; Centra | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Patient outcomes following subepithelial connective tissue graft and free gingival graft procedures.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue; Female; Gingiva; Gingival R | 2008 |
Gender differences in analgesia for endodontic pain.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Combinations; Female; Humans | 2008 |
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Dose-Response Relationship, Drug; Double-Blind Me | 2008 |
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Dose-Response Relationship, Drug; Double-Blind Me | 2008 |
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Dose-Response Relationship, Drug; Double-Blind Me | 2008 |
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Dose-Response Relationship, Drug; Double-Blind Me | 2008 |
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Dose-Response Relationship, Drug; Double-Blind Me | 2008 |
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Dose-Response Relationship, Drug; Double-Blind Me | 2008 |
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Dose-Response Relationship, Drug; Double-Blind Me | 2008 |
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Dose-Response Relationship, Drug; Double-Blind Me | 2008 |
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Dose-Response Relationship, Drug; Double-Blind Me | 2008 |
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Dose-Response Relationship, Drug; Double-Blind Me | 2008 |
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Dose-Response Relationship, Drug; Double-Blind Me | 2008 |
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Dose-Response Relationship, Drug; Double-Blind Me | 2008 |
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Dose-Response Relationship, Drug; Double-Blind Me | 2008 |
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Dose-Response Relationship, Drug; Double-Blind Me | 2008 |
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Dose-Response Relationship, Drug; Double-Blind Me | 2008 |
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Dose-Response Relationship, Drug; Double-Blind Me | 2008 |
Evaluation of pretreatment analgesia and endodontic treatment for postoperative endodontic pain.
Topics: Adult; Analgesics, Non-Narcotic; Analysis of Variance; Dental Pulp Necrosis; Double-Blind Method; Fa | 2008 |
Evaluation of pretreatment analgesia and endodontic treatment for postoperative endodontic pain.
Topics: Adult; Analgesics, Non-Narcotic; Analysis of Variance; Dental Pulp Necrosis; Double-Blind Method; Fa | 2008 |
Evaluation of pretreatment analgesia and endodontic treatment for postoperative endodontic pain.
Topics: Adult; Analgesics, Non-Narcotic; Analysis of Variance; Dental Pulp Necrosis; Double-Blind Method; Fa | 2008 |
Evaluation of pretreatment analgesia and endodontic treatment for postoperative endodontic pain.
Topics: Adult; Analgesics, Non-Narcotic; Analysis of Variance; Dental Pulp Necrosis; Double-Blind Method; Fa | 2008 |
Ibuprofen in the treatment of postoperative pain.
Topics: Acetaminophen; Age Factors; Analgesics, Opioid; Anesthesia, Epidural; Aspirin; Cholecystectomy; Clin | 1984 |
Suppression of postoperative pain by preoperative administration of ibuprofen in comparison to placebo, acetaminophen, and acetaminophen plus codeine.
Topics: Acetaminophen; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Therapy, Combination; Hu | 1983 |
New peripherally-acting oral analgesic agents.
Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials | 1983 |
Comparison of ibuprofen and acetaminophen-codeine in postoperative foot pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug | 1984 |
Ibuprofen, zomepirac, aspirin, and placebo in the relief of postepisiotomy pain.
Topics: Adolescent; Adult; Aspirin; Episiotomy; Female; Humans; Ibuprofen; Pain, Postoperative; Placebos; Py | 1983 |
Analgesia following dental surgery: a comparison of brufen and distalgesic.
Topics: Acetaminophen; Adolescent; Adult; Dextropropoxyphene; Double-Blind Method; Drug Combinations; Female | 1981 |
Relief of postoperative pain by ibuprofen: a report of two studies.
Topics: Adolescent; Adult; Aged; Analgesics; Aspirin; Clinical Trials as Topic; Codeine; Drug Combinations; | 1980 |
Double-blind evaluation of naproxen and ibuprofen in periodontal surgery.
Topics: Acetaminophen; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Gingivectomy; Humans; | 1980 |
Ibuprofen versus placebo in the relief of post-episiotomy pain.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Episiotomy; Female; Humans; Ibuprofen; Pain, P | 1981 |
A double-blind comparison of ibuprofen, ASA-codeine-caffeine compound and placebo in the treatment of dental surgery pain.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Clinical Trials as Topic; Codeine | 1981 |
Recovery from outpatient laparoscopic tubal ligation is not improved by preoperative administration of ketorolac or ibuprofen.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans | 1994 |
Prophylactic oral ibuprofen or ibuprofen-codeine versus placebo for postoperative pain after primary hip arthroplasty.
Topics: Administration, Oral; Aged; Codeine; Double-Blind Method; Drug Therapy, Combination; Hip Prosthesis; | 1995 |
Use of ibuprofen and methylprednisolone for the prevention of pain and swelling after removal of impacted third molars.
Topics: Adolescent; Adult; Cheek; Double-Blind Method; Drug Combinations; Edema; Female; Humans; Ibuprofen; | 1995 |
Use of ibuprofen and methylprednisolone for the prevention of pain and swelling after removal of impacted third molars.
Topics: Adolescent; Adult; Cheek; Double-Blind Method; Drug Combinations; Edema; Female; Humans; Ibuprofen; | 1995 |
Use of ibuprofen and methylprednisolone for the prevention of pain and swelling after removal of impacted third molars.
Topics: Adolescent; Adult; Cheek; Double-Blind Method; Drug Combinations; Edema; Female; Humans; Ibuprofen; | 1995 |
Use of ibuprofen and methylprednisolone for the prevention of pain and swelling after removal of impacted third molars.
Topics: Adolescent; Adult; Cheek; Double-Blind Method; Drug Combinations; Edema; Female; Humans; Ibuprofen; | 1995 |
Ibuprofen in the treatment of postoperative pain in small children. A randomized double-blind-placebo controlled parallel group study.
Topics: Administration, Rectal; Analgesics, Non-Narcotic; Anesthesia, Spinal; Blood Pressure; Child, Prescho | 1994 |
Effectiveness of various medications on postoperative pain following complete instrumentation.
Topics: Acetaminophen; Adult; Analysis of Variance; Chi-Square Distribution; Codeine; Dental Anxiety; Erythr | 1994 |
Effectiveness of various medications on postoperative pain following root canal obturation.
Topics: Acetaminophen; Adult; Aged; Analysis of Variance; Chi-Square Distribution; Codeine; Erythromycin; Fe | 1994 |
A placebo-controlled comparative evaluation of diclofenac dispersible versus ibuprofen in postoperative pain after third molar surgery.
Topics: Administration, Oral; Adult; Aged; Diclofenac; Double-Blind Method; Female; Humans; Ibuprofen; Male; | 1994 |
Ketorolac versus acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory A | 1994 |
Clinical evaluation of H1-receptor and H2-receptor antagonists for acute postoperative pain.
Topics: Acute Disease; Adult; Double-Blind Method; Female; Humans; Ibuprofen; Male; Molar, Third; Pain, Post | 1993 |
Single dose and multidose analgesic study of ibuprofen and meclofenamate sodium after third molar surgery.
Topics: Abdominal Pain; Adolescent; Adult; Analysis of Variance; Chi-Square Distribution; Diarrhea; Dose-Res | 1993 |
Narcotic receptor blockade and its effect on the analgesic response to placebo and ibuprofen after oral surgery.
Topics: Adult; Analysis of Variance; Chi-Square Distribution; Codeine; Double-Blind Method; Drug Synergism; | 1993 |
The analgesic efficacy of diclofenac dispersible and ibuprofen in postoperative pain after dental extraction.
Topics: Administration, Oral; Adolescent; Adult; Analgesia; Diclofenac; Double-Blind Method; Female; Humans; | 1993 |
A multiple dose comparison of ibuprofen and dihydrocodeine after third molar surgery.
Topics: Administration, Oral; Adult; Analgesics; Analysis of Variance; Chi-Square Distribution; Codeine; Diz | 1993 |
The effect of an ibuprofen-codeine combination for the treatment of patients with pain after removal of lower third molars.
Topics: Administration, Oral; Adolescent; Adult; Codeine; Double-Blind Method; Drug Combinations; Female; Hu | 1993 |
Ibuprofen controlled-release formulation. A clinical trial in dental impaction pain.
Topics: Adult; Analysis of Variance; Chi-Square Distribution; Codeine; Delayed-Action Preparations; Double-B | 1993 |
Evaluation of different doses of soluble ibuprofen and ibuprofen tablets in postoperative dental pain.
Topics: Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Dose- | 1996 |
Ibuprofen compared with ibuprofen plus caffeine after third molar surgery.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous System Stimulants; Double- | 1996 |
A comparison of ibuprofen arginine with morphine sulphate for pain relief after orthopaedic surgery.
Topics: Administration, Oral; Adolescent; Adult; Aged; Analgesics, Opioid; Double-Blind Method; Female; Huma | 1996 |
A study to compare ibuprofen effervescent granules with ibuprofen tablets in the treatment of acute dental pain.
Topics: Acute Disease; Adolescent; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Chi | 1994 |
Effect of a non-steroidal anti-inflammatory drug on tissue levels of immunoreactive prostaglandin E2, immunoreactive leukotriene, and pain after periodontal surgery.
Topics: Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Dinoprostone; D | 1996 |
The effect of nitrous oxide and carbon dioxide pneumoperitoneum on operative and postoperative pain during laparoscopic sterilization under local anesthesia.
Topics: Administration, Oral; Adult; Alfentanil; Analgesia; Analgesics, Opioid; Anesthesia, Local; Anestheti | 1994 |
Benzodiazepine mediated antagonism of opioid analgesia.
Topics: Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Anxiety Agents; Diazepam; Double-Blind Met | 1997 |
[Preventive analgesic effect of intraoperative administration of ibuprofen-arginine on postmastectomy pain syndrome].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Follow-Up Studies; Humans; Ibu | 1997 |
Are the pharmacokinetics of ibuprofen important determinants for the drug's efficacy in postoperative pain after third molar surgery?
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non- | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
Ibuprofen elevates immunoreactive beta-endorphin levels in humans during surgical stress.
Topics: Adult; Analysis of Variance; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroi | 1997 |
Postoperative analgesia with preoperative oral ibuprofen or acetaminophen in children undergoing myringotomy.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid | 1997 |
The analgesic efficacy of ibuprofen in periodontal surgery: A multicentre study.
Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, Dental; Anesthesia, Local; Anti-Inflammatory Agents | 1997 |
Analgesic efficacy of a hydrocodone with ibuprofen combination compared with ibuprofen alone for the treatment of acute postoperative pain.
Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroid | 1997 |
Comparison of the safety and efficacy of a combination analgesic Myprodol and Ponstan in the treatment of dental pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 1992 |
Evaluation of trismus, bite force, and pressure algometry after third molar surgery: a placebo-controlled study of ibuprofen.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Bite Force; Double-Blind Method; Female; | 1998 |
Preemptive pain control in patients having laparoscopic hernia repair: a comparison of ketorolac and ibuprofen.
Topics: Administration, Oral; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blin | 1998 |
Oral metamizol (1 g and 2 g) versus ibuprofen and placebo in the treatment of lower third molar surgery pain: randomised double-blind multi-centre study. Cooperative Study Group.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double-Blind Method; Facial Pain; Female; | 1998 |
Analgesic dose-response relationship of ibuprofen 50, 100, 200, and 400 mg after surgical removal of third molars: a single-dose, randomized, placebo-controlled, and double-blind study of 304 patients.
Topics: Adult; Analgesia; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relat | 1998 |
Enhanced analgesia and suppression of plasma beta-endorphin by the S(+)-isomer of ibuprofen.
Topics: Adult; Analgesics, Non-Narcotic; beta-Endorphin; Double-Blind Method; Female; Humans; Ibuprofen; Iso | 1998 |
[Management of postoperative pain in stomatology with ibuprofen L-arginine and naproxen].
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Female; Humans; Ibuprofen; Inf | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
The comparative efficacy of aceclofenac and ibuprofen in postoperative pain after third molar surgery.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Chi-Square Distribution; Diclofena | 1998 |
Analgesic efficacy of a combination of hydrocodone with ibuprofen in postoperative pain.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Synergism; Drug | 1999 |
The efficacy of a novel adenosine agonist (WAG 994) in postoperative dental pain.
Topics: Adenosine; Adult; Double-Blind Method; Female; Humans; Ibuprofen; Male; Molar, Third; Pain, Postoper | 1999 |
Analgesic efficacy of the cyclooxygenase-2-specific inhibitor rofecoxib in post-dental surgery pain: a randomized, controlled trial.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxy | 1999 |
Baseline pain and response to analgesic medications in the postsurgery dental pain model.
Topics: Adolescent; Adult; Female; Humans; Ibuprofen; Male; Middle Aged; Pain, Postoperative; Tooth Extracti | 2000 |
Single-dose vicoprofen compared with acetaminophen with codeine and placebo in patients with acute postoperative pain after third molar extractions.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Analysis of Variance; Chi-Square Distribution; Codeine | 2000 |
Combination hydrocodone and ibuprofen versus combination oxycodone and acetaminophen in the treatment of postoperative obstetric or gynecologic pain.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Analge | 2000 |
The effect of dextromethorphan, alone or in combination with ibuprofen, on postoperative pain after minor gynaecological surgery.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Dextromethorphan; Double-Blind Method; Drug Therapy, | 2000 |
Prospective double-blind randomised study of a new regimen of pre-emptive analgesia for inguinal hernia repair: evaluation of postoperative pain course.
Topics: Adult; Aged; Analgesia; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Meth | 2000 |
Dose-response effect of combination hydrocodone with ibuprofen in patients with moderate to severe postoperative pain.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Humans; Hydrocodone; Ibupr | 2000 |
An open-label evaluation of the efficacy and safety of Stadol NS with ibuprofen in the treatment of pain after removal of impacted wisdom teeth.
Topics: Administration, Inhalation; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opio | 2000 |
Effectiveness of Stadol NS (butorphanol tartrate) with ibuprofen in the treatment of pain after laser-assisted uvulopalatopharyngoplasty.
Topics: Administration, Inhalation; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioi | 2000 |
A new therapeutic scheme of ibuprofen to treat postoperatory endodontic dental pain.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Child; Dental Pulp Cavity; Double- | 2000 |
Pain control after routine dento-alveolar day surgery: a patient satisfaction survey.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Dental Audi | 2000 |
Ibuprofen liquigel for oral surgery pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Chemistry, Pharmaceutical; Dose-Response Relationshi | 2000 |
The optimal analgesic dose of rofecoxib: Overview of six randomized controlled trials.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase | 2000 |
Onset and duration of analgesia for low-dose ketoprofen in the treatment of postoperative dental pain.
Topics: Adolescent; Adult; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, D | 1998 |
Oral ibuprofen versus paracetamol plus codeine for analgesia after ambulatory surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-In | 2001 |
Pregabalin in patients with postoperative dental pain.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia, Local; Anticonvulsants; Double-Blind Method | 2001 |
The effectiveness of prophylactic etodolac on postendodontic pain.
Topics: Acute Disease; Administration, Oral; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammato | 2000 |
Effect of apical trephination on postoperative pain and swelling in symptomatic necrotic teeth.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Anti-Infla | 2001 |
Effect of prophylactic amoxicillin on endodontic flare-up in asymptomatic, necrotic teeth.
Topics: Acetaminophen; Adult; Amoxicillin; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Varianc | 2001 |
Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla | 2001 |
Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla | 2001 |
Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla | 2001 |
Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla | 2001 |
Onset of analgesia for liquigel ibuprofen 400 mg, acetaminophen 1000 mg, ketoprofen 25 mg, and placebo in the treatment of postoperative dental pain.
Topics: Abdominal Pain; Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory | 2001 |
Double-blind, placebo-controlled analgesic study of ibuprofen or rofecoxib in combination with paracetamol for tonsillectomy in children.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-St | 2002 |
Comparative analgesic potency of aspirin and ibuprofen.
Topics: Analgesics; Aspirin; Drug Evaluation; Humans; Ibuprofen; Pain, Postoperative; Placebos; Tooth, Impac | 1977 |
Analgesic activity of ibuprofen (Motrin) in postoperative oral surgical pain.
Topics: Adolescent; Adult; Aged; Analgesics; Aspirin; Clinical Trials as Topic; Dextropropoxyphene; Double-B | 1978 |
Evaluation of preoperative ibuprofen for postoperative pain after removal of third molars.
Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Drug Int | 1978 |
Ridit analysis in dental clinical studies.
Topics: Aspirin; Clinical Trials as Topic; Double-Blind Method; Humans; Ibuprofen; Pain, Postoperative; Plac | 1979 |
Idarac v ibuprofen in the relief of dental pain.
Topics: Adolescent; Adult; Analgesics; Clinical Trials as Topic; Female; Humans; Ibuprofen; Male; Middle Age | 1976 |
Bilateral surgical removal of impacted lower third molar teeth as a model for drug evaluation: a test with ibuprofen.
Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Evaluation; Edema; Female; Hemostasis; Humans; Ibu | 1975 |
[Analgesic effect of ibuprofen in pain after episiotomy].
Topics: Acetaminophen; Adult; Double-Blind Method; Drug Evaluation; Episiotomy; Female; Humans; Ibuprofen; P | 1992 |
Analgesic efficacy of an ibuprofen-codeine combination in patients with pain after removal of lower third molars.
Topics: Adolescent; Adult; Analgesia; Aspirin; Codeine; Double-Blind Method; Drug Combinations; Female; Huma | 1992 |
Comparison of presurgical and immediate postsurgical ibuprofen on postoperative periodontal pain.
Topics: Adult; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Pain Measurement; Pain, Po | 1992 |
Pain control after third molar surgery--a comparative study of ibuprofen (Ibumetin) and a paracetamol/codeine combination (Citodon).
Topics: Acetaminophen; Adolescent; Adult; Codeine; Drug Combinations; Edema; Female; Humans; Ibuprofen; Male | 1992 |
A multiple dose comparison of combinations of ibuprofen and codeine and paracetamol, codeine and caffeine after third molar surgery.
Topics: Acetaminophen; Administration, Oral; Adult; Caffeine; Codeine; Double-Blind Method; Drug Combination | 1992 |
Analgesic efficacy of bromfenac, ibuprofen, and aspirin in postoperative oral surgery pain.
Topics: Aspirin; Benzophenones; Bromobenzenes; Dose-Response Relationship, Drug; Double-Blind Method; Humans | 1992 |
Double blind study on emorfazone and ibuprofen in dental pain and inflammation.
Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Ibu | 1992 |
Efficacy of rectal ibuprofen in controlling postoperative pain in children.
Topics: Administration, Rectal; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; | 1992 |
[A comparison of a tramadol/metamizole infusion with the combination tramadol infusion plus ibuprofen suppositories for postoperative pain management following hysterectomy].
Topics: Adult; Aged; Dipyrone; Double-Blind Method; Female; Humans; Hysterectomy, Vaginal; Ibuprofen; Infusi | 1992 |
Ibuprofen provides longer lasting analgesia than fentanyl after laparoscopic surgery.
Topics: Administration, Oral; Double-Blind Method; Female; Fentanyl; Humans; Ibuprofen; Injections, Intraven | 1991 |
Evaluation of an ibuprofen controlled-release tablet and placebo in postoperative oral surgery pain.
Topics: Administration, Oral; Adolescent; Adult; Ambulatory Surgical Procedures; Analgesics; Delayed-Action | 1991 |
An evaluation of different ibuprofen preparations in the control of postoperative pain after third molar surgery.
Topics: Adolescent; Adult; Capsules; Female; Humans; Ibuprofen; Male; Middle Aged; Molar, Third; Pain, Posto | 1991 |
An evaluation of different ibuprofen preparations in the control of postoperative pain after third molar surgery.
Topics: Adolescent; Adult; Capsules; Female; Humans; Ibuprofen; Male; Middle Aged; Molar, Third; Pain, Posto | 1991 |
An evaluation of different ibuprofen preparations in the control of postoperative pain after third molar surgery.
Topics: Adolescent; Adult; Capsules; Female; Humans; Ibuprofen; Male; Middle Aged; Molar, Third; Pain, Posto | 1991 |
An evaluation of different ibuprofen preparations in the control of postoperative pain after third molar surgery.
Topics: Adolescent; Adult; Capsules; Female; Humans; Ibuprofen; Male; Middle Aged; Molar, Third; Pain, Posto | 1991 |
Evaluation of bromfenac, aspirin, and ibuprofen in postoperative oral surgery pain.
Topics: Administration, Oral; Adolescent; Adult; Analgesics; Aspirin; Benzophenones; Bromobenzenes; Dose-Res | 1991 |
Effect of caffeine on ibuprofen analgesia in postoperative oral surgery pain.
Topics: Adolescent; Adult; Analgesia; Analysis of Variance; Caffeine; Dentistry, Operative; Drug Therapy, Co | 1991 |
Evaluation of ketorolac, ibuprofen, acetaminophen, and an acetaminophen-codeine combination in postoperative oral surgery pain.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesia; Anti-Inflammatory Agents, Non-Ste | 1990 |
Multicenter clinical trial of ibuprofen and acetaminophen in the treatment of postoperative dental pain.
Topics: Acetaminophen; Adolescent; Adult; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; | 1990 |
A study of the comparative efficacy of four common analgesics in the control of postsurgical dental pain.
Topics: Acetaminophen; Adult; Analgesics; Analysis of Variance; Aspirin; Caffeine; Codeine; Drug Combination | 1990 |
A comparison of ibuprofen and ibuprofen-codeine combination in the relief of post-operative oral surgery pain.
Topics: Adolescent; Adult; Aged; Codeine; Double-Blind Method; Drug Combinations; Drug Interactions; Humans; | 1990 |
A comparison of four analgesics in post-episiotomy pain.
Topics: Acetaminophen; Analgesics; Aspirin; Dipyrone; Episiotomy; Female; Humans; Ibuprofen; Pain, Postopera | 1990 |
Comparison of nonsteroidal anti-inflammatory drugs, ibuprofen and flurbiprofen, with methylprednisolone and placebo for acute pain, swelling, and trismus.
Topics: Adult; Double-Blind Method; Evaluation Studies as Topic; Female; Fever; Flurbiprofen; Humans; Ibupro | 1990 |
Comparison of nonsteroidal anti-inflammatory drugs, ibuprofen and flurbiprofen, with methylprednisolone and placebo for acute pain, swelling, and trismus.
Topics: Adult; Double-Blind Method; Evaluation Studies as Topic; Female; Fever; Flurbiprofen; Humans; Ibupro | 1990 |
Comparison of nonsteroidal anti-inflammatory drugs, ibuprofen and flurbiprofen, with methylprednisolone and placebo for acute pain, swelling, and trismus.
Topics: Adult; Double-Blind Method; Evaluation Studies as Topic; Female; Fever; Flurbiprofen; Humans; Ibupro | 1990 |
Comparison of nonsteroidal anti-inflammatory drugs, ibuprofen and flurbiprofen, with methylprednisolone and placebo for acute pain, swelling, and trismus.
Topics: Adult; Double-Blind Method; Evaluation Studies as Topic; Female; Fever; Flurbiprofen; Humans; Ibupro | 1990 |
A randomized double-blind clinical trial on the effectiveness of helium-neon laser in the prevention of pain, swelling and trismus after removal of impacted third molars.
Topics: Adult; Double-Blind Method; Edema; Female; Humans; Ibuprofen; Laser Therapy; Male; Molar, Third; Pai | 1990 |
Ibuprofen and acetaminophen in the relief of postpartum episiotomy pain.
Topics: Acetaminophen; Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Episiotomy; Female; | 1989 |
Ibuprofen and acetaminophen in the relief of acute pain: a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Double-Blind Method; Female; Humans; Ibuprofen; Mal | 1989 |
A comparison of ibuprofen and dihydrocodeine in relieving pain following wisdom teeth removal.
Topics: Adolescent; Adult; Aged; Codeine; Female; Humans; Ibuprofen; Male; Middle Aged; Molar, Third; Pain M | 1989 |
A double-blind placebo-controlled comparison of three ibuprofen/codeine combinations and aspirin.
Topics: Aspirin; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; Humans; Ibuprofe | 1986 |
A single dose assessment of an ibuprofen/codeine combination in postoperative dental pain.
Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combination | 1986 |
Ibuprofen given pre- and post-operatively for the relief of pain.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Codeine; Diflunisal; Double-Blind Method; Drug Co | 1987 |
Photogrammetry used to assess post-operative facial swelling in a drug trial.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Face; Female; Humans; Ibuprofen; I | 1985 |
Analgesic efficacy of two ibuprofen-codeine combinations for the treatment of postepisiotomy and postoperative pain.
Topics: Adult; Cesarean Section; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; | 1987 |
Syrup formulations for post-tonsillectomy analgesia: a double-blind study comparing ibuprofen, aspirin and placebo.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Metho | 1986 |
The relative efficacy of ibuprofen in dental pain.
Topics: Clinical Trials as Topic; Humans; Ibuprofen; Pain Measurement; Pain, Postoperative; Tooth Diseases | 1986 |
Ibuprofen in the management of postoperative pain.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ibuprofen; Morphine; Pain, Pos | 1986 |
A double-blind comparison of the new ibuprofen-codeine phosphate combination, zomepirac, and placebo in the relief of postepisiotomy pain.
Topics: Adult; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; Episiotomy; Female | 1985 |
A comparative study of the efficacy of aspirin and an ibuprofen/codeine combination in patients treated pre-operatively with methylprednisolone acetate.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Codeine; Double-Blin | 1985 |
Postextraction pain relief in children: a clinical trial of liquid analgesics.
Topics: Acetaminophen; Analgesics; Child; Child, Preschool; Clinical Trials as Topic; Codeine; Double-Blind | 1985 |
Efficacy and quality of ibuprofen and acetaminophen plus codeine analgesia.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Codeine; Drug Combinations; Drug Evaluation; Emo | 1985 |
153 other studies available for ibuprofen and Pain, Postoperative
| Article | Year |
|---|---|
An observational cohort study comparing ibuprofen and oxycodone in children with fractures.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Co | 2021 |
The NOpioid Project: a prospective observational feasibility study examining the implementation of a non-narcotic post-operative pain control regimen.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Appendectomy; Appendicitis; Feas | 2022 |
Acetaminophen: Is Too Much of a Good Thing Too Much?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2022 |
Opioid Consumption After Urogynecologic Surgery: A Prospective Multicenter Observational Study Using a Text-Messaging Survey Tool.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cohort Studies; Female; Humans; Ibuprof | 2022 |
A Prospective Analysis of Opioid Use Following Outpatient Pediatric Urologic Surgery.
Topics: Acetaminophen; Analgesics, Opioid; Child; Child, Preschool; Female; Humans; Ibuprofen; Male; Opioid- | 2022 |
Use of Scheduled Nonopioid Analgesia to Decrease Inpatient Opioid Consumption After Scheduled Cesarean Birth.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans; Ibuprofen; I | 2022 |
Green Light Exposure Elicits Anti-inflammation, Endogenous Opioid Release and Dampens Synaptic Potentiation to Relieve Post-surgical Pain.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Female; Humans; Ibuprofen; Male; Morphine; Ne | 2023 |
Problems in self-management of analgesics after outpatient shoulder surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opi | 2022 |
Effect of ibuprofen on severity of surgically-managed pediatric post-tonsillectomy hemorrhage.
Topics: Child; Female; Humans; Ibuprofen; Male; Pain, Postoperative; Postoperative Hemorrhage; Prospective S | 2023 |
Remote smart pill cap monitoring of post-surgical pain management in thyroid and parathyroid surgery.
Topics: Acetaminophen; Analgesics, Opioid; Humans; Ibuprofen; Pain, Postoperative; Pilot Projects; Prospecti | 2023 |
Paracetamol and ibuprofen combination for the management of acute mild-to-moderate pain in children: expert consensus using the Nominal Group Technique (NGT).
Topics: Acetaminophen; Acute Pain; Administration, Oral; Analgesics, Non-Narcotic; Child; Consensus; Drug Co | 2023 |
Opioid-Sparing Protocol for Endocrine Surgery (OSPREY): A Prospective Study.
Topics: Acetaminophen; Analgesics, Opioid; Humans; Ibuprofen; Pain, Postoperative; Prospective Studies | 2023 |
Does Liposomal Bupivacaine Injectable Suspension Peripheral Nerve Block Further Aid in Decreasing At-home Narcotic Utilization in Children and Adolescents After Anterior Cruciate Ligament Reconstruction.
Topics: Acetaminophen; Adolescent; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anterior Cruciate Lig | 2023 |
A service evaluation of the impact of parental information provision on analgesia administration at home posttonsillectomy.
Topics: Acetaminophen; Analgesia; Analgesics; Child; Humans; Ibuprofen; Morphine; Pain, Postoperative; Paren | 2023 |
There are probably no added benefits of intravenous ketamine for postoperative pain in patients undergoing third-molar extraction who receive perioperative antibiotics, ibuprofen, and dexamethasone.
Topics: Anti-Bacterial Agents; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketamine; Molar; Molar | 2020 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
An alternative technique for effective pain management in upper extremity surgery: erector spinae plane block.
Topics: Adult; Anesthetics, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Fentanyl; Humans; Humerus; | 2020 |
The effect of a scheduled regimen of acetaminophen and ibuprofen on opioid use following cesarean delivery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2020 |
Single-Dose Oral Ibuprofen Plus Caffeine for Acute Postoperative Pain in Adults.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous Syst | 2020 |
Effect of Over the Counter Ibuprofen Dosing after Sinus Surgery for Chronic Rhinosinusitis: A Prospective Cohort Pilot Study.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Chronic Disease; Cohort St | 2020 |
Intraoperative intravenous ibuprofen use is not associated with increased post-tonsillectomy bleeding.
Topics: Adenoidectomy; Administration, Intravenous; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Chi | 2020 |
No pain is gain: A prospective evaluation of strict non-opioid pain control after pediatric appendectomy.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Appendectomy; Appendicitis; | 2020 |
National opioid prescription patterns and patient usage after routine vasectomy.
Topics: Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Prescriptions; Dr | 2020 |
High dose ibuprofen as a monotherapy on an around-the-clock basis fails to control pain in children undergoing tonsil surgery: a prospective observational cohort study.
Topics: Child; Child, Preschool; Humans; Ibuprofen; Infant; Pain, Postoperative; Palatine Tonsil; Prospectiv | 2020 |
Parental assessment of pain control following pediatric adenotonsillectomy: Do opioids make a difference?
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child | 2020 |
A comprehensive model for pain management in patients undergoing pelvic reconstructive surgery: a prospective clinical practice study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2020 |
Patient's pre-operative dental anxiety is related to diastolic blood pressure and the need for post-surgical analgesia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Blood Pressure; Dental Anxiety; Diastole; Dr | 2020 |
Postoperative pain after tonsillectomy - the value of standardized analgesic treatment protocols.
Topics: Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Dipyrone; Female; Humans; Ibuprofen; Male; Morp | 2020 |
The Effect of Ibuprofen Dosing Interval on Post-Tonsillectomy Outcomes in Children: A Quality Improvement Study.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Drug Administration Schedule; Emergency Service, Hos | 2020 |
Metamizole but not ibuprofen reduces the plasma concentration of sertraline: Implications for the concurrent treatment of pain and depression/anxiety disorders.
Topics: Anxiety Disorders; Depression; Dipyrone; Humans; Ibuprofen; Pain, Postoperative; Selective Serotonin | 2021 |
Patient Satisfaction and Refill Rates After Decreasing Opioids Prescribed for Urogynecologic Surgery.
Topics: Acetaminophen; Analgesia; Analgesics; Analgesics, Opioid; Clinical Protocols; Combined Modality Ther | 2020 |
Small trial did not find evidence that preemptive use of acetaminophen or ibuprofen reduces perioperative pain in children undergoing primary molar extraction.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Humans; Ibuprofen; Molar; Pain, Postoperative | 2020 |
Pediatric Post-Tonsillectomy Opioid Prescribing Practices.
Topics: Acetaminophen; Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; Child | 2021 |
Does Ibuprofen Increase Bleed Risk for Pediatric Tonsillectomy?
Topics: Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Blood Transfusion; Child; Child, Preschool; Fem | 2021 |
CYP450 polymorphisms and clinical pharmacogenetics of ibuprofen after lower third molar extraction.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Body Mass Index; Cytochrome P-450 CYP2C8 | 2021 |
Effectiveness of ibuprofen plus paracetamol combination on persistence of acute musculoskeletal disorders in primary care patients.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Midd | 2021 |
Parental Assessment of Pain Control Following Pediatric Circumcision: Do Opioids Make a Difference?
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Ci | 2021 |
Association of perioperative ibuprofen exposure with post-tonsillectomy bleeding requiring operative management.
Topics: Adenoidectomy; Adolescent; Child; Child, Preschool; Humans; Ibuprofen; Infant; Infant, Newborn; Pain | 2021 |
Evaluation and comparison of anti-inflammatory properties of ibuprofen using two drug delivery systems after third molar surgery: using chitosan microspheres as a carrier for local drug delivery in to the third molar socket and through the oral route.
Topics: Anti-Inflammatory Agents; Chitosan; Drug Delivery Systems; Edema; Humans; Ibuprofen; Mandible; Micro | 2021 |
Pain in children undergoing tonsillotomy with alternating ibuprofen and paracetamol - a prospective observational study.
Topics: Acetaminophen; Child; Humans; Ibuprofen; Infant; Pain Measurement; Pain, Postoperative; Tonsillectom | 2021 |
Reduction of Opioid Overprescribing and Use Following Standardized Educational Intervention: A Survey of Patient Experiences Following Anorectal Procedures.
Topics: Acetaminophen; Adult; Anal Canal; Analgesics, Non-Narcotic; Analgesics, Opioid; Colorectal Surgery; | 2021 |
Topical Ropivacaine in Prevention of Post-Tonsillectomy Pain in Adults.
Topics: Acetaminophen; Adolescent; Adult; Ambulatory Surgical Procedures; Amides; Analgesics, Non-Narcotic; | 2017 |
Pharmacological advances in the multimodal management of perioperative analgesia.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Clinical Trials as Topic; Combined Modality Therapy; Dexm | 2017 |
Association Between Ibuprofen Use and Severity of Surgically Managed Posttonsillectomy Hemorrhage.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Transfusion; Child; Child, Preschool; Female; Humans; | 2017 |
Postoperative Pain Management following Thoracic Outlet Decompression.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Decompression, Surgical; Diaze | 2017 |
Local infiltration of the surgical wounds with levobupivacaine, dexibuprofen, and norepinephrine to reduce postoperative pain: A randomized, vehicle-controlled, and preclinical study.
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Drug Evaluation, Preclinical; Drug Ther | 2017 |
Insufficient evidence to support benefits of ibuprofen sodium dihydrate over ibuprofen acid to reduce pain in patients with acute odontogenic pain.
Topics: Acute Pain; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; | 2017 |
Local infiltration of the surgical wound with levobupivacaine, ibuprofen, and epinephrine in postoperative pain: An experimental study.
Topics: Analgesics, Non-Narcotic; Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Drug Administ | 2017 |
Gender and arch effects on the use of non-opioid analgesics for post endodontic pain reduction.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; | 2018 |
Pain after tonsillectomy: effectiveness of current guidelines?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Drug Therapy, | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
The effect of postoperative steroids on post-tonsillectomy pain and need for postoperative physician contact.
Topics: Acetaminophen; Anti-Inflammatory Agents; Child; Child, Preschool; Dexamethasone; Emergency Service, | 2018 |
The effect of postoperative steroids on post-tonsillectomy pain and need for postoperative physician contact.
Topics: Acetaminophen; Anti-Inflammatory Agents; Child; Child, Preschool; Dexamethasone; Emergency Service, | 2018 |
The effect of postoperative steroids on post-tonsillectomy pain and need for postoperative physician contact.
Topics: Acetaminophen; Anti-Inflammatory Agents; Child; Child, Preschool; Dexamethasone; Emergency Service, | 2018 |
The effect of postoperative steroids on post-tonsillectomy pain and need for postoperative physician contact.
Topics: Acetaminophen; Anti-Inflammatory Agents; Child; Child, Preschool; Dexamethasone; Emergency Service, | 2018 |
Safety of preoperative ibuprofen in pediatric tonsillectomy.
Topics: Adenoids; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Case-Control Studies; Child; C | 2018 |
Continuous local bupivacaine wound infusion with neuraxial morphine reduces opioid consumption after cesarean delivery.
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, S | 2019 |
Implementing a standardised discharge analgesia guideline to reduce paediatric post tonsillectomy pain.
Topics: Acetaminophen; Adolescent; Analgesia; Analgesics; Child; Child, Preschool; Clinical Protocols; Drug | 2018 |
Development of Multimodal Analgesia Pathways in Outpatient Thyroid and Parathyroid Surgery and Association With Postoperative Opioid Prescription Patterns.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics; Analgesics, Opioid; Anti-Inflammatory Age | 2018 |
Analgesic Effect of Local Infiltration of the Surgical Wound Containing Levobupivacaine, Ibuprofen, and Epinephrine in Rats Undergoing Laparotomy.
Topics: Abdominal Wound Closure Techniques; Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Epinephri | 2018 |
Opioid Use Following Operatively Treated Pediatric Elbow and Femur Fractures.
Topics: Adolescent; Ambulatory Care; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; | 2019 |
The Utility of Oral Nonsteroidal Anti-inflammatory Drugs Compared With Standard Opioids Following Arthroscopic Meniscectomy: A Prospective Observational Study.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Parents' attitudes toward post-operative narcotic use in pediatric patients.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Caregivers; Child; Child, Preschool; Female; He | 2019 |
Danger of highlighting the use of coxibs in daily dental practice.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Humans; Ibuprofen; | 2019 |
In response to Letter to the Editor "Danger of highlighting the use of coxibs in daily dental practice".
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Humans; Ibuprofen; | 2019 |
How low can you go: Achieving postoperative outpatient pain control without opioids.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Appendectomy; Cholecystectomy, Laparosc | 2019 |
The advantages and limitations of the analgesics available for control of postoperative pain after a dental procedure.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspiri | 2013 |
Surgical suture assembled with polymeric drug-delivery sheet for sustained, local pain relief.
Topics: Analgesics; Animals; Delayed-Action Preparations; Diffusion; Equipment Design; Equipment Failure Ana | 2013 |
Limited evidence that single-dose oral ibuprofen plus codeine is more effective for postoperative pain than either drug alone.
Topics: Analgesics, Opioid; Codeine; Humans; Ibuprofen; Pain, Postoperative | 2014 |
Ultrasound-guided rectus sheath block for pyloromyotomy in infants: a retrospective analysis of a case series.
Topics: Analgesics, Opioid; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal; Female; Fentanyl; | 2013 |
The application of clinical audit to improve pain control following third molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 2013 |
A prescription for pain relief.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Drug Overdose; Female; Hu | 2014 |
Acetaminophen plus ibuprofen versus opioids for treatment of post-tonsillectomy pain in children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Dehydration; D | 2014 |
Ibuprofen with acetaminophen for postoperative pain control following tonsillectomy does not increase emergency department utilization.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Age Factors; Analgesics; Child; Child, Preschool; Codeine; | 2014 |
Maternal satisfaction with analgesia following hospital discharge after caesarean section.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, No | 2015 |
Ibuprofen is superior to paracetamol for pain relief following third molar removal.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Humans; Ibuprofen; Molar, Third; Pain, Postoperative; Tooth | 2014 |
Ibuprofen and acetaminophen for posttonsillectomy pain.
Topics: Acetaminophen; Codeine; Emergency Service, Hospital; Female; Humans; Ibuprofen; Male; Pain, Postoper | 2015 |
Ibuprofen with acetaminophen for tonsillectomy pain.
Topics: Acetaminophen; Codeine; Emergency Service, Hospital; Female; Humans; Ibuprofen; Male; Pain, Postoper | 2015 |
Outcomes of an Alternating Ibuprofen and Acetaminophen Regimen for Pain Relief After Tonsillectomy in Children.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Female; | 2015 |
Postoperative pain control after tonsillectomy.
Topics: Acetaminophen; Codeine; Dexamethasone; Emergency Service, Hospital; Female; Humans; Ibuprofen; Male; | 2015 |
A survey of the administration of prednisolone versus ibuprofen analgesic protocols after ambulatory tonsillectomy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-In | 2015 |
Postoperative nonsteroidal anti-inflammatory drugs and risk of bleeding in pediatric intracapsular tonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Chi | 2015 |
Letter to the Editor.
Topics: Acetaminophen; Adenoidectomy; Female; Humans; Ibuprofen; Male; Pain, Postoperative; Postoperative He | 2016 |
Oral morphine for pain management in paediatric patients after tonsillectomy and adenotonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics | 2015 |
Effect size comparison of ketorolac nasal spray and commonly prescribed oral combination opioids for pain relief after third molar extraction surgery.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Anti-Inflammatory Agents | 2016 |
Response to Letter to the Editor by Bakshi et al.
Topics: Acetaminophen; Adenoidectomy; Animals; Bone and Bones; Chickens; Female; Fishes; Foreign Bodies; Hum | 2016 |
The effectiveness of a single dose of oral ibuprofen plus caffeine in acute postoperative pain in adults.
Topics: Acute Pain; Analgesics, Non-Narcotic; Caffeine; Humans; Ibuprofen; Pain, Postoperative | 2016 |
Postoperative Pain in Children After Dentistry Under General Anesthesia.
Topics: Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, General; Anti-Inflammatory Agents, Non-S | 2015 |
Nitric oxide is involved in ibuprofen preemptive analgesic effect in the plantar incisional model of postsurgical pain in mice.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Arginine; Hindlimb; Hyperalgesia; Ibup | 2016 |
A Comparison of Nonopioid and Opioid Oral Analgesia Following Pediatric Palatoplasty.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Combinations | 2017 |
Analgesic management after thoracotomy for decortication in children: a retrospective audit of 83 children managed with a paravertebral infusion-based regime.
Topics: Acetaminophen; Adolescent; Analgesia; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opi | 2016 |
The Use of Ibuprofen in Posttonsillectomy Analgesia and Its Effect on Posttonsillectomy Hemorrhage Rate.
Topics: Adenoidectomy; Adolescent; Age Factors; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, | 2016 |
Minimizing pain medication use and its associated costs following robotic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics; Anti-Inflammatory Agents, Non-Steroi | 2017 |
Analgesia following adenotonsillar surgery in children: is Oramorph required in addition to paracetamol and ibuprofen?
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child | 2017 |
Effects of intravenous ibuprofen and lornoxicam on erythrocyte deformability in rats undergoing hind limb ischemia reperfusion injury.
Topics: Administration, Intravenous; Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Erythrocyt | 2016 |
Pain management for dentists.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspiri | 2008 |
Prescriptions of NSAIDs to patients undergoing third molar surgery : an observational, prospective, multicentre survey.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Dental Health Surveys; Diclofenac; Drug Prescription | 2008 |
Post-operative pain: the impact of prescribing patterns on nurses' administration of analgesia.
Topics: Acetaminophen; Analgesia; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Child; Codeine; Diclo | 2008 |
Delayed pinpoint purpura after fractionated carbon dioxide treatment in a patient taking ibuprofen in the postoperative period.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Laser Therapy; Lasers, Gas; Midd | 2009 |
Evidence for the use of non-steroidal anti-inflammatory drugs for acute pain in the post anaesthesia care unit.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; C | 2009 |
Prediction of postoperative pain after mandibular third molar surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anxiety; Attitude; Depression; Eating; Female; Follo | 2010 |
Good evidence supports ibuprofen as an effective and safe analgesic for postoperative pain.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Pain, Postoper | 2010 |
Safety and utility of scheduled nonnarcotic analgesic medications in children undergoing craniotomy for brain tumor.
Topics: Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; B | 2010 |
Reducing postoperative pain by changing the process.
Topics: Acetaminophen; Acute Pain; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Non-N | 2011 |
The effect of ibuprofen on postoperative hemorrhage following tonsillectomy in children.
Topics: Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Dose-Response R | 2011 |
IL6 and TNF expression in vessels and surrounding tissues after embolization with ibuprofen-loaded beads confirms diffusion of ibuprofen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Drug Delivery Systems | 2011 |
Post-craniotomy pain in a paediatric population.
Topics: Acetaminophen; Adolescent; Age Factors; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, | 2011 |
Relative efficacy of oral analgesics after third molar extraction--a 2011 update.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Facial Pain; | 2011 |
Transversus abdominis plane catheters for post-cesarean delivery analgesia: a series of five cases.
Topics: Abdominal Muscles; Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; | 2012 |
Tears at breakfast.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Child, Preschool; Drug Ther | 2012 |
The effect of paracetamol, metamizole sodium and ibuprofen on postoperative hemorrhage following pediatric tonsillectomy.
Topics: Acetaminophen; Analgesics; Child; Child, Preschool; Dipyrone; Female; Humans; Ibuprofen; Male; Pain, | 2012 |
Post-operative pain and pain management in children after dental extractions under general anaesthesia.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, Dental; Anesthesia, General; Child; Child, Pres | 2012 |
Effect of drainage upon access on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 2002 |
Postoperative complaints following impacted mandibular third molar surgery in Ile-Ife, Nigeria.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Edema; Female; Humans; Ibuprofen; Male; | 2002 |
Over-the-counter oral analgesia for postcesarean pain.
Topics: Administration, Oral; Analgesia, Patient-Controlled; Analgesics; Capsules; Cesarean Section; Drug Ad | 2002 |
Can the use of specific isomers improve the safety and efficacy of nonsteroidal antiinflammatory drugs?
Topics: Analgesia; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibupr | 2003 |
[Regional anesthesia for urologic interventions in the pediatric age group].
Topics: Acetaminophen; Age Factors; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthesia, Co | 2004 |
Parecoxib versus ibuprofen.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Humans; Ib | 2005 |
[Diagnosis at a glance. Nearly asphyxiated by own tongue].
Topics: Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Asphyxia; Drug Hypersensitivity; Humans; Ibupro | 2005 |
A teenager with severe asthma exacerbation following ibuprofen.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Contraindications; Humans; Ibu | 2005 |
Perioperative pharmacokinetics of ibuprofen enantiomers after rectal administration.
Topics: Administration, Rectal; Adult; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Fem | 2005 |
Pain management after hernia repair.
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Hernia, Inguinal; Humans; Ibuprofen; Infu | 2005 |
Effects of pre-emptive morphine, ibuprofen or local anesthetic on fos expression in the spinal trigeminal nucleus following tooth pulp exposure in the rat.
Topics: Analgesics, Opioid; Analysis of Variance; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non | 2005 |
Pharmaceutical prescribing for children. Part 2. Analgesia and prescribing for children in pain.
Topics: Acetaminophen; Adolescent; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammato | 2005 |
Ibuprofen before gum surgery doubles bleeding. NSAIDS are more effective in reducing pain and swelling when taken after surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical; Female; Gingiva; Humans; Ibuprofen; M | 2005 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Mi | 2006 |
An analysis of current analgesic preferences for endodontic pain management.
Topics: Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cross-Sectional Studies; Dr | 2006 |
Scheduled oral analgesics and the need for opiates in children following partial dorsal rhizotomy.
Topics: Acetaminophen; Administration, Oral; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Cerebral P | 2007 |
[Ambulatory pain management for children in the family practice].
Topics: Acetaminophen; Acute Disease; Ambulatory Care; Analgesics; Analgesics, Opioid; Child; Chronic Diseas | 2007 |
The effects of nonsteroidal anti-inflammatory analgesics on pain after periodontal surgery.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind M | 1984 |
Five studies on ibuprofen for postsurgical dental pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Aspirin; Codeine; Drug Combinations; Female; Humans; I | 1984 |
The effect of Ibuprofen (Brufen) following the removal of impacted third molar teeth.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Molar, T | 1983 |
A study comparing the effectiveness of Ibuprofen (Motrin), Empirin with Codeine #3, and Synalgos-DC for the relief of postendodontic pain.
Topics: Adolescent; Adult; Aspirin; Codeine; Drug Combinations; Female; Humans; Ibuprofen; Male; Middle Aged | 1984 |
Excretion of ibuprofen into breast milk.
Topics: Adult; Breast Feeding; Chromatography, Gas; Female; Humans; Ibuprofen; Infant, Newborn; Milk, Human; | 1984 |
[Clinical results of ibuprofen suppository (UP-sup) in orosurgical field].
Topics: Adolescent; Adult; Aged; Female; Humans; Ibuprofen; Jaw Diseases; Male; Middle Aged; Pain, Postopera | 1981 |
[Clinical results of ibuprofen suppository (UP-sup) in orosurgical field].
Topics: Adult; Aged; Female; Humans; Ibuprofen; Male; Middle Aged; Pain, Postoperative; Suppositories; Tooth | 1981 |
Dental surgery pain analgesic.
Topics: Adolescent; Adult; Codeine; Double-Blind Method; Drug Evaluation; Female; Humans; Ibuprofen; Male; P | 1980 |
Ketorolac versus ibuprofen: a simple cost-efficacy comparison for dental use.
Topics: Analgesics; Cost-Benefit Analysis; Humans; Ibuprofen; Ketorolac; Pain, Postoperative; Tolmetin; Toot | 1994 |
Sleep after laparoscopic cholecystectomy.
Topics: Adult; Aged; Analgesia; Anesthesia, General; Cholecystectomy, Laparoscopic; Female; Humans; Ibuprofe | 1996 |
Pain and activity disturbance after paediatric day case adenoidectomy.
Topics: Acetaminophen; Activities of Daily Living; Adenoidectomy; Ambulatory Surgical Procedures; Analgesics | 1997 |
Anesthesiology.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Ketorolac; Pain, Postoperative; Piroxica | 1998 |
Additive analgesic effects of oxycodone and ibuprofen in the oral surgery model.
Topics: Adult; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Dental; Anti-Inflammatory Agents, | 1999 |
Reporting of adverse effects in clinical trials should be improved: lessons from acute postoperative pain.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Double-Blind Method; Humans; Ibuprofen; Pain | 1999 |
Audit of pain management at home following tonsillectomy in children.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Chi-Square Distribution; Ch | 2001 |
Nonsteroidal anti-inflammatory drugs for perioperative pain control.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac | 2001 |
Gastrointestinal bleeds associated with rofecoxib.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Gastrointestinal Hemorrhag | 2002 |
[Ibuprofen: an analgesic for our time].
Topics: Humans; Ibuprofen; Pain, Postoperative; Tooth Extraction | 1991 |
The efficacy and safety of ketoprofen in postsurgical dental pain.
Topics: Double-Blind Method; Humans; Ibuprofen; Ketoprofen; Molar, Third; Pain Measurement; Pain, Postoperat | 1991 |
Analgesics for dental pain.
Topics: Acetaminophen; Aspirin; Humans; Ibuprofen; Pain, Postoperative; Surgery, Oral | 1991 |
[Postoperative monitoring of pain under ibuprofen lysinate].
Topics: Adult; Female; Humans; Ibuprofen; Lysine; Male; Molar, Third; Pain, Postoperative; Tooth Extraction | 1990 |
Analgesic side effects and minor surgery: which analgesic for minor and day-case surgery?
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics; Codeine; Drug Combinations; Female | 1990 |
[Ibuprofen as an analgesic in surgery in jaw region].
Topics: Analgesics; Humans; Ibuprofen; Orthognathic Surgical Procedures; Pain, Postoperative | 1988 |
[Comparative study of analgesics].
Topics: Dextropropoxyphene; Humans; Ibuprofen; Mouth; Pain, Postoperative; Pyrazoles; Tooth, Impacted | 1986 |
Ibuprofen use in surgical periodontics.
Topics: Humans; Ibuprofen; Pain, Postoperative; Periodontal Diseases | 1985 |
Prescribing analgesics.
Topics: Acetaminophen; Aged; Analgesics; Anticoagulants; Aspirin; Child; Codeine; Diflunisal; Drug Hypersens | 1985 |