Page last updated: 2024-10-28

ibuprofen and Pain, Chronic

ibuprofen has been researched along with Pain, Chronic in 22 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to see if the use of low level continuous heat (LLCH) and Ibuprofen used as a home therapy between physical therapy sessions at a clinic resulted in better therapy outcomes in people with chronic neck pain."9.24Use of low level of continuous heat and Ibuprofen as an adjunct to physical therapy improves pain relief, range of motion and the compliance for home exercise in patients with nonspecific neck pain: A randomized controlled trial. ( Alshammari, F; Khowailed, IA; Laymon, M; Lee, H; Petrofsky, JS, 2017)
"Ibuprofen and paracetamol have long been used as analgesics in a range of acute, intermittent and chronic pain conditions."8.91Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions. ( Aldington, DJ; Derry, S; Moore, RA; Straube, S; Wiffen, PJ, 2015)
" The aim of the present study was to clarify whether plant-derived isoflavone puerarin could ameliorate comorbid depression and pain."7.85Plant Natural Product Puerarin Ameliorates Depressive Behaviors and Chronic Pain in Mice with Spared Nerve Injury (SNI). ( Lao, L; Liang, Z; Luo, D; Rong, J; Zhao, J, 2017)
"The purpose of this study was to see if the use of low level continuous heat (LLCH) and Ibuprofen used as a home therapy between physical therapy sessions at a clinic resulted in better therapy outcomes in people with chronic neck pain."5.24Use of low level of continuous heat and Ibuprofen as an adjunct to physical therapy improves pain relief, range of motion and the compliance for home exercise in patients with nonspecific neck pain: A randomized controlled trial. ( Alshammari, F; Khowailed, IA; Laymon, M; Lee, H; Petrofsky, JS, 2017)
"We know from adult randomised controlled trials that some NSAIDs, such as ibuprofen, naproxen, and aspirin, can be effective in certain chronic pain conditions."4.95Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents. ( Anderson, B; Cooper, TE; Eccleston, C; Fisher, E; Wilkinson, NM, 2017)
"Ibuprofen and paracetamol have long been used as analgesics in a range of acute, intermittent and chronic pain conditions."4.91Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions. ( Aldington, DJ; Derry, S; Moore, RA; Straube, S; Wiffen, PJ, 2015)
" In patients with neuropathic pain, topical forms of both capsaicin and lidocaine have been shown to be useful in the treatment of postherpetic neuralgia and diabetic peripheral neuropathic pain."4.89Topical therapies in the management of chronic pain. ( Galluzzi, KE; Stanos, SP, 2013)
" The aim of the present study was to clarify whether plant-derived isoflavone puerarin could ameliorate comorbid depression and pain."3.85Plant Natural Product Puerarin Ameliorates Depressive Behaviors and Chronic Pain in Mice with Spared Nerve Injury (SNI). ( Lao, L; Liang, Z; Luo, D; Rong, J; Zhao, J, 2017)
"Patientssufferingfromacute trauma (group A (symptoms existent up to 48 hours) as well as patients with chronic symptoms (group B) experienced a fast and prominent improvement of symptoms."2.78[Topical gel formulation of ibuprofen in the treatment of acute and chronic joint and soft tissue pain. Results of a non-interventional observational trial]. ( Petersen-Braun, M; Wegener, T, 2013)
"The 17 patients treated for acute or chronic pain during the opioid-free shift were managed mainly with i."1.42Development of an opioid reduction protocol in an emergency department. ( Bosoy, D; Cohen, V; Fromm, C; Hossain, R; Jellinek-Cohen, SP; Likourezos, A; Marshall, J; Motov, S; Rockoff, B; Smith, A, 2015)
"The target population was HIV and AIDS patients who had been using the primary health clinic for chronic pain management."1.39The management of HIV- and AIDS-related pain in a primary health clinic in Tshwane, South Africa. ( Dreyer Wright, SC; Makua, MR; Maree, JE, 2013)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's20 (90.91)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Wu, YJ1
Guernon, J1
McClure, A1
Luo, G1
Rajamani, R1
Ng, A1
Easton, A1
Newton, A1
Bourin, C1
Parker, D1
Mosure, K1
Barnaby, O1
Soars, MG1
Knox, RJ1
Matchett, M1
Pieschl, R1
Herrington, J1
Chen, P1
Sivarao, DV1
Bristow, LJ1
Meanwell, NA1
Bronson, J1
Olson, R1
Thompson, LA1
Dzierba, C1
Chen, ZJ3
Su, CW3
Xiong, S3
Li, T3
Liang, HY3
Lin, YH3
Chang, L3
Wu, HY3
Li, F3
Zhu, DY3
Luo, CX3
Stevens, J1
Bhalla, T1
Dhokia, M1
Elander, J1
Clements, K1
Gilbert, P1
Eccleston, C1
Cooper, TE1
Fisher, E1
Anderson, B1
Wilkinson, NM1
Hao, D1
Olugbodi, A1
Udechukwu, N1
Donato, AA1
Radman, M1
Babic, A1
Runjic, E1
Jelicic Kadic, A1
Jeric, M1
Moja, L1
Puljak, L1
Petersen-Braun, M1
Wegener, T1
Maree, JE1
Dreyer Wright, SC1
Makua, MR1
Chaparro, LE1
Smith, SA1
Moore, RA2
Wiffen, PJ2
Gilron, I1
Stanos, SP1
Galluzzi, KE1
Derry, S1
Straube, S1
Aldington, DJ1
Nielsen, RV1
Siegel, H1
Fomsgaard, JS1
Andersen, JDH1
Martusevicius, R1
Mathiesen, O1
Dahl, JB1
Cohen, V1
Motov, S1
Rockoff, B1
Smith, A1
Fromm, C1
Bosoy, D1
Hossain, R1
Likourezos, A1
Jellinek-Cohen, SP1
Marshall, J1
Enthoven, WT1
Roelofs, PD1
Deyo, RA1
van Tulder, MW1
Koes, BW1
Zhao, J1
Luo, D1
Liang, Z1
Lao, L1
Rong, J1
Hultzsch, S1
Schaefer, C1
Petrofsky, JS1
Laymon, M1
Alshammari, F1
Khowailed, IA1
Lee, H1
Andrews, N1
Harper, S1
Issop, Y1
Rice, AS1
Du, Y1
Ellert, U1
Zhuang, W1
Knopf, H1
Woitzek, K1
Park, SC1
Kim, KH1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Trial Evaluating multimOdal toPical Cream In CompArison to pLacebo (TOPICAL)[NCT03199417]Phase 2/Phase 350 participants (Actual)Interventional2017-05-01Terminated (stopped due to Terminated prematurely due to feasibility issues with rate of recruitment)
Hypoalgesic Effect of Median Nerve Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group[NCT02596815]51 participants (Actual)Interventional2015-07-31Completed
Hypoalgesic Effect of Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group[NCT02595294]52 participants (Actual)Interventional2015-07-31Completed
Hypoalgesic Effect of Median Nerve Neural Mobilization Versus Ibuprofen Pharmacologic Treatment in Patients With Cervicobrachial Pain[NCT02593721]Phase 2/Phase 350 participants (Actual)Interventional2015-07-31Completed
Randomized Double-blind Controlled Study to Assess the Efficacy of Intravenous Acetaminophen Associated With Strong Opioids in the Management of Acute Pain in Adult Cancer Patients[NCT04779567]Phase 4112 participants (Actual)Interventional2019-06-10Completed
The Effect of Dexamethasone in Combination With Paracetamol and Ibuprofen as Adjuvant, Postoperative Pain After Herniated Disc Surgery[NCT01953978]Phase 4160 participants (Actual)Interventional2012-12-31Completed
The Effect of 4 Hours of Tens and Heat on Pain and Range of Motion in the Lower Back and the Duration of Pain Relief After Tens and Heat Are Removed[NCT03740750]90 participants (Anticipated)Interventional2018-10-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for ibuprofen and Pain, Chronic

ArticleYear
Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents.
    The Cochrane database of systematic reviews, 2017, 08-02, Volume: 8

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Arthritis, Rheumatoid; Asp

2017
Revisiting established medicines: An overview of systematic reviews about ibuprofen and paracetamol for treating pain in children.
    European journal of pain (London, England), 2019, Volume: 23, Issue:6

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N

2019
Pharmacotherapy for the prevention of chronic pain after surgery in adults.
    The Cochrane database of systematic reviews, 2013, Jul-24, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Femal

2013
Topical therapies in the management of chronic pain.
    Postgraduate medicine, 2013, Volume: 125, Issue:4 Suppl 1

    Topics: Administration, Cutaneous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; C

2013
Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions.
    European journal of pain (London, England), 2015, Volume: 19, Issue:9

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Humans; Ibuprofen

2015
Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions.
    European journal of pain (London, England), 2015, Volume: 19, Issue:9

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Humans; Ibuprofen

2015
Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions.
    European journal of pain (London, England), 2015, Volume: 19, Issue:9

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Humans; Ibuprofen

2015
Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions.
    European journal of pain (London, England), 2015, Volume: 19, Issue:9

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Humans; Ibuprofen

2015
Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions.
    European journal of pain (London, England), 2015, Volume: 19, Issue:9

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Humans; Ibuprofen

2015
Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions.
    European journal of pain (London, England), 2015, Volume: 19, Issue:9

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Humans; Ibuprofen

2015
Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions.
    European journal of pain (London, England), 2015, Volume: 19, Issue:9

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Humans; Ibuprofen

2015
Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions.
    European journal of pain (London, England), 2015, Volume: 19, Issue:9

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Humans; Ibuprofen

2015
Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions.
    European journal of pain (London, England), 2015, Volume: 19, Issue:9

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Humans; Ibuprofen

2015
Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions.
    European journal of pain (London, England), 2015, Volume: 19, Issue:9

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Humans; Ibuprofen

2015
Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions.
    European journal of pain (London, England), 2015, Volume: 19, Issue:9

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Humans; Ibuprofen

2015
Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions.
    European journal of pain (London, England), 2015, Volume: 19, Issue:9

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Humans; Ibuprofen

2015
Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions.
    European journal of pain (London, England), 2015, Volume: 19, Issue:9

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Humans; Ibuprofen

2015
Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions.
    European journal of pain (London, England), 2015, Volume: 19, Issue:9

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Humans; Ibuprofen

2015
Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions.
    European journal of pain (London, England), 2015, Volume: 19, Issue:9

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Humans; Ibuprofen

2015
Overview review: Comparative efficacy of oral ibuprofen and paracetamol (acetaminophen) across acute and chronic pain conditions.
    European journal of pain (London, England), 2015, Volume: 19, Issue:9

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Humans; Ibuprofen

2015
Non-steroidal anti-inflammatory drugs for chronic low back pain.
    The Cochrane database of systematic reviews, 2016, Feb-10, Volume: 2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Diclofenac; Disability Evaluation; Humans; Ib

2016
[Analgesic drugs during pregnancy].
    Schmerz (Berlin, Germany), 2016, Volume: 30, Issue:6

    Topics: Abnormalities, Drug-Induced; Acetaminophen; Acute Pain; Analgesics; Analgesics, Opioid; Anticonvulsa

2016

Trials

6 trials available for ibuprofen and Pain, Chronic

ArticleYear
A randomized-controlled pilot trial of an online compassionate mind training intervention to help people with chronic pain avoid analgesic misuse.
    Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2020, Volume: 34, Issue:7

    Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Arthritis, Rheumatoid; Aspirin; Back Pain; Chr

2020
[Topical gel formulation of ibuprofen in the treatment of acute and chronic joint and soft tissue pain. Results of a non-interventional observational trial].
    MMW Fortschritte der Medizin, 2013, Mar-21, Volume: 155 Suppl 1

    Topics: Acute Pain; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Chr

2013
Preoperative dexamethasone reduces acute but not sustained pain after lumbar disk surgery: a randomized, blinded, placebo-controlled trial.
    Pain, 2015, Volume: 156, Issue:12

    Topics: Acetaminophen; Acute Pain; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammato

2015
Use of low level of continuous heat and Ibuprofen as an adjunct to physical therapy improves pain relief, range of motion and the compliance for home exercise in patients with nonspecific neck pain: A randomized controlled trial.
    Journal of back and musculoskeletal rehabilitation, 2017, Volume: 30, Issue:4

    Topics: Adult; Aged; Analgesics, Non-Narcotic; Chronic Pain; Combined Modality Therapy; Exercise; Exercise T

2017
[Ibuprofen/paracetamol combination therapy is more effective than monotherapy in knee pain, but increases bleeding risk].
    Praxis, 2012, Mar-14, Volume: 101, Issue:6

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pai

2012
Effect of adding cervical facet joint injections in a multimodal treatment program for long-standing cervical myofascial pain syndrome with referral pain patterns of cervical facet joint syndrome.
    Journal of anesthesia, 2012, Volume: 26, Issue:5

    Topics: Acetaminophen; Anesthetics, General; Chronic Pain; Clonidine; Codeine; Combined Modality Therapy; Do

2012

Other Studies

9 other studies available for ibuprofen and Pain, Chronic

ArticleYear
Discovery of non-zwitterionic aryl sulfonamides as Na
    Bioorganic & medicinal chemistry, 2017, 10-15, Volume: 25, Issue:20

    Topics: Administration, Oral; Animals; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Dru

2017
Enhanced AMPAR-dependent synaptic transmission by S-nitrosylation in the vmPFC contributes to chronic inflammatory pain-induced persistent anxiety in mice.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:5

    Topics: Animals; Anxiety; Anxiety Disorders; Chronic Pain; Ibuprofen; Inflammation; Mice; Prefrontal Cortex;

2023
Enhanced AMPAR-dependent synaptic transmission by S-nitrosylation in the vmPFC contributes to chronic inflammatory pain-induced persistent anxiety in mice.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:5

    Topics: Animals; Anxiety; Anxiety Disorders; Chronic Pain; Ibuprofen; Inflammation; Mice; Prefrontal Cortex;

2023
Enhanced AMPAR-dependent synaptic transmission by S-nitrosylation in the vmPFC contributes to chronic inflammatory pain-induced persistent anxiety in mice.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:5

    Topics: Animals; Anxiety; Anxiety Disorders; Chronic Pain; Ibuprofen; Inflammation; Mice; Prefrontal Cortex;

2023
Enhanced AMPAR-dependent synaptic transmission by S-nitrosylation in the vmPFC contributes to chronic inflammatory pain-induced persistent anxiety in mice.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:5

    Topics: Animals; Anxiety; Anxiety Disorders; Chronic Pain; Ibuprofen; Inflammation; Mice; Prefrontal Cortex;

2023
A new OPIATE (Optimizing Positive Ibuprofen and Acetaminophen Treatment Expectations) model: A brief comment on "Concurrent and lagged associations of prescription opioid use with pain and negative affect in the daily lives of chronic pain patients" (Carp
    Journal of consulting and clinical psychology, 2019, Volume: 87, Issue:10

    Topics: Acetaminophen; Affect; Analgesics, Opioid; Chronic Pain; Humans; Ibuprofen; Motivation; Opiate Alkal

2019
Trauma-induced adiposis dolorosa (Dercum's disease).
    BMJ case reports, 2018, Mar-28, Volume: 2018

    Topics: Accidents, Traffic; Adipose Tissue; Adiposis Dolorosa; Adult; Amitriptyline; Analgesics, Non-Narcoti

2018
The management of HIV- and AIDS-related pain in a primary health clinic in Tshwane, South Africa.
    Pain management nursing : official journal of the American Society of Pain Management Nurses, 2013, Volume: 14, Issue:2

    Topics: Acetaminophen; Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Analgesics, Non-Narcotic

2013
Development of an opioid reduction protocol in an emergency department.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2015, Dec-01, Volume: 72, Issue:23

    Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Chronic Pain; Emergency Service, Hospital; Humans

2015
Plant Natural Product Puerarin Ameliorates Depressive Behaviors and Chronic Pain in Mice with Spared Nerve Injury (SNI).
    Molecular neurobiology, 2017, Volume: 54, Issue:4

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Biological Products; Brain-Derived Neurotrophic Fa

2017
Novel, nonreflex tests detect analgesic action in rodents at clinically relevant concentrations.
    Annals of the New York Academy of Sciences, 2011, Volume: 1245

    Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Chronic Pain; Freund's Adjuvant; Hu

2011
Analgesic use in a national community sample of German children and adolescents.
    European journal of pain (London, England), 2012, Volume: 16, Issue:6

    Topics: Acetaminophen; Acute Pain; Adolescent; Analgesics; Aspirin; Child; Child, Preschool; Chronic Pain; F

2012