Page last updated: 2024-10-28

ibuprofen and Overweight

ibuprofen has been researched along with Overweight in 3 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Overweight: A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal over fat.

Research Excerpts

ExcerptRelevanceReference
"The efficacy and tolerability of ibuprofen treatment in obese children and presence of any adverse drug reactions."3.01Ibuprofen efficacy, tolerability and safety in obese children: a systematic review. ( Gill, A; Hawcutt, DB; Huws, A; McWilliam, SJ; Shamsaee, E, 2023)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's3 (100.00)2.80

Authors

AuthorsStudies
Shamsaee, E3
Huws, A3
Gill, A3
McWilliam, SJ3
Hawcutt, DB3
Skou, ST1
Roos, EM1
Laursen, M1
Arendt-Nielsen, L1
Rasmussen, S1
Simonsen, O1
Ibsen, R1
Larsen, AT1
Kjellberg, J1
Stoffel, NU1
Cepeda-Lopez, AC1
Cervantes-Gracia, K1
Llanas-Cornejo, D1
Delgado González, EA1
Herter-Aeberli, I1
Zimmermann, MB1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Structured Non-operative Treatment of Knee Osteoarthritis - a Randomized Controlled Trial of Pain, Physical Function and Quality of Life With 12months Follow-up[NCT01535001]100 participants (Actual)Interventional2012-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in 20-meter Walk

(NCT01535001)
Timeframe: Primary: 12months.

Interventionsec (Mean)
MEDIC-1.2
Standard Treatment-0.6

Change From Baseline in KOOS4 (Knee Injury and Osteoarthritis Outcome Score)

"The average score for four of the five KOOS subscales, covering pain, symptoms, difficulties in functions of daily living, and quality of life (KOOS4), with scores ranging from 0 (worst) to 100 (best).~Between group comparisons of treatment effect (change in KOOS4 from baseline to 1 year follow-up) will be dependent on data distribution. We expect the change to be normally distributed and analysis will be made using a mixed model ANOVA with subject being a random factor and visit (baseline, 3, 6 and 12 months), treatment arm (TKA + MEDIC, MEDIC) and site (Frederikshavn, Farsoe) being fixed factors. Baseline KOOS4 will be a covariate. Furthermore interactions between the fixed factors will be included in the model. P-values and 95% CI will be presented to assess superiority." (NCT01535001)
Timeframe: Primary: 12months.

Interventionunits on a scale (Mean)
MEDIC18.2
Standard Treatment7.1

Change From Baseline in Time From the Timed Up and Go

(NCT01535001)
Timeframe: Primary: 12 months.

Interventionsec (Mean)
MEDIC-1.4
Standard Treatment-1.1

Number of Serious Adverse Events Reported at Index Knee

Adverse events (AE) and seriously adverse events (SAE) will be registered in three ways and divided into index knee or sites other than index knee. The project physiotherapist will record any adverse events that the participant experiences or tells them about. For the participants allocated to, or crossing over to, TKA, a project worker will look through hospital records to register if any pre-defined perioperative and postoperative adverse events occurred. At all follow-ups, the assessor will use open-probe questioning to assess adverse events in all participants. (NCT01535001)
Timeframe: Primary: 12months.

InterventionSerious adverse events related to knee (Number)
MEDIC13
Standard Treatment24

Weight Change in kg From Baseline

Weight change in kg measured without shoes at the same time of day and on the same scale (NCT01535001)
Timeframe: Primary: 12months.

Interventionkg (Mean)
MEDIC-2.4
Standard Treatment-2.4

Change From Baseline in EQ-5D

"Between groups comparisons of the change from baseline to the 1 year follow-up in all secondary endpoint will be handled similar to the primary endpoint. See statistical analysis plan for further description (available under Links).~Range of EQ-5D Descriptive Index is -0.59 to 1.00 (worst to best), while the EQ VAS goes from 0 to 100 (worst to best)." (NCT01535001)
Timeframe: Primary: 12months.

,
Interventionunits on a scale (Mean)
Descriptive indexEQ VAS
MEDIC0.1405.3
Standard Treatment0.0757.2

Change in the Five KOOS Subscale Scores From Baseline

Range of all subscales are 0 to 100 (worst to best). (NCT01535001)
Timeframe: Primary: 12 months.

,
Interventionunits on a scale (Number)
PainSymptomsActivities of Daily LivingSports and recreationQuality of Life
MEDIC18.716.318.716.019.0
Standard Treatment9.37.75.912.05.5

Proportion of Users of Pain Medication

With possible answers being yes and no (NCT01535001)
Timeframe: Baseline and 12months.

,
Interventionproportion of participants (Number)
Baseline12months
MEDIC0.640.39
Standard Treatment0.560.57

Reviews

1 review available for ibuprofen and Overweight

ArticleYear
Ibuprofen efficacy, tolerability and safety in obese children: a systematic review.
    Archives of disease in childhood, 2023, Volume: 108, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Humans; Ibuprofen; Overweight; Pediatric Obesity; Retrospective

2023
Ibuprofen efficacy, tolerability and safety in obese children: a systematic review.
    Archives of disease in childhood, 2023, Volume: 108, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Humans; Ibuprofen; Overweight; Pediatric Obesity; Retrospective

2023
Ibuprofen efficacy, tolerability and safety in obese children: a systematic review.
    Archives of disease in childhood, 2023, Volume: 108, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Humans; Ibuprofen; Overweight; Pediatric Obesity; Retrospective

2023
Ibuprofen efficacy, tolerability and safety in obese children: a systematic review.
    Archives of disease in childhood, 2023, Volume: 108, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Humans; Ibuprofen; Overweight; Pediatric Obesity; Retrospective

2023
Ibuprofen efficacy, tolerability and safety in obese children: a systematic review.
    Archives of disease in childhood, 2023, Volume: 108, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Humans; Ibuprofen; Overweight; Pediatric Obesity; Retrospective

2023
Ibuprofen efficacy, tolerability and safety in obese children: a systematic review.
    Archives of disease in childhood, 2023, Volume: 108, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Humans; Ibuprofen; Overweight; Pediatric Obesity; Retrospective

2023
Ibuprofen efficacy, tolerability and safety in obese children: a systematic review.
    Archives of disease in childhood, 2023, Volume: 108, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Humans; Ibuprofen; Overweight; Pediatric Obesity; Retrospective

2023
Ibuprofen efficacy, tolerability and safety in obese children: a systematic review.
    Archives of disease in childhood, 2023, Volume: 108, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Humans; Ibuprofen; Overweight; Pediatric Obesity; Retrospective

2023
Ibuprofen efficacy, tolerability and safety in obese children: a systematic review.
    Archives of disease in childhood, 2023, Volume: 108, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Humans; Ibuprofen; Overweight; Pediatric Obesity; Retrospective

2023

Trials

1 trial available for ibuprofen and Overweight

ArticleYear
Cost-effectiveness of 12 weeks of supervised treatment compared to written advice in patients with knee osteoarthritis: a secondary analysis of the 2-year outcome from a randomized trial.
    Osteoarthritis and cartilage, 2020, Volume: 28, Issue:7

    Topics: Aged; Analgesics, Non-Narcotic; Cost-Benefit Analysis; Denmark; Diet Therapy; Exercise Therapy; Fema

2020

Other Studies

1 other study available for ibuprofen and Overweight

ArticleYear
The effects of reducing chronic inflammation in overweight women on serum hepcidin and iron absorption with and without supplemental ascorbic acid.
    The British journal of nutrition, 2021, 09-28, Volume: 126, Issue:6

    Topics: Adult; Ascorbic Acid; Female; Hepcidins; Humans; Ibuprofen; Inflammation; Interleukin-6; Intestinal

2021