Page last updated: 2024-10-28

ibuprofen and Orthopedic Disorders

ibuprofen has been researched along with Orthopedic Disorders in 6 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy of IM ketorolac versus that of oral ibuprofen in acute musculoskeletal pain."9.08Intramuscular ketorolac versus oral ibuprofen in acute musculoskeletal pain. ( Paris, PM; Seaberg, DC; Turturro, MA, 1995)
"To evaluate the efficacy of IM ketorolac versus that of oral ibuprofen in acute musculoskeletal pain."5.08Intramuscular ketorolac versus oral ibuprofen in acute musculoskeletal pain. ( Paris, PM; Seaberg, DC; Turturro, MA, 1995)
"Ibuprofen was statistically equivalent to paracetamol and better tolerated than aspirin (p <0."2.70Comparative tolerability of paracetamol, aspirin and ibuprofen for short-term analgesia in patients with musculoskeletal conditions: results in 4291 patients. ( Le Parc, JM; Moore, N; Schneid, H; Van Ganse, E; Verrière, F; Wall, R, 2002)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Bettiol, A1
Marconi, E1
Vannacci, A1
Simonetti, M1
Magni, A1
Cricelli, C1
Lapi, F1
Le May, S1
Ali, S1
Plint, AC1
Mâsse, B1
Neto, G1
Auclair, MC1
Drendel, AL1
Ballard, A1
Khadra, C1
Villeneuve, E1
Parent, S1
McGrath, PJ1
Leclair, G1
Gouin, S1
Korownyk, C1
Young, J1
Michael Allan, G1
Graudins, A1
Meek, R1
Parkinson, J1
Egerton-Warburton, D1
Meyer, A1
Turturro, MA1
Paris, PM1
Seaberg, DC1
Le Parc, JM1
Van Ganse, E1
Moore, N1
Wall, R1
Schneid, H1
Verrière, F1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Controlled Trial of Oral Analgesic Utilization for Pain Management of CHildhood Musculoskeletal Injuries[NCT02064894]501 participants (Actual)Interventional2013-07-08Completed
A Randomized Double-blinded Trial Comparing the Clinical Efficacy and Pharmacokinetic Parameters of Oral Diclofenac and Intramuscular Diclofenac in Patients With Acute Limb Injuries[NCT03472339]Phase 4300 participants (Anticipated)Interventional2018-01-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Pain Intensity - Percentage of Children Who Achieved VAS < 30 mm

"Percentage of participants which pain intensity has decreased under 30 mm on the VAS at 60 minutes.~The Visual Analogue Scale is a 0 to 100 mm continuous scale measuring the pain intensity. Score of 0=No Pain; Score of 100=Worst imaginable pain" (NCT02064894)
Timeframe: 60 minutes post-analgesia

InterventionPercentage of participants (Number)
Oral Morphine and Oral Ibuprofen33.0
Morphine and Placebo of Ibuprofen29.3
Ibuprofen and Placebo of Morphine29.9

Serious Adverse Event - Side Effects and Serious Adverse Events

To verify the occurence of any serious adverse event, such as respiratory depression or deep sedation, during all the time-periods of the study (NCT02064894)
Timeframe: 60, 90 and 120 minutes

,,
InterventionParticipants (Count of Participants)
Side effectsSerious adverse event
Ibuprofen and Placebo of Morphine380
Morphine and Placebo of Ibuprofen390
Oral Morphine and Oral Ibuprofen60

Trials

4 trials available for ibuprofen and Orthopedic Disorders

ArticleYear
Oral Analgesics Utilization for Children With Musculoskeletal Injury (OUCH Trial): An RCT.
    Pediatrics, 2017, Volume: 140, Issue:5

    Topics: Administration, Oral; Adolescent; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ster

2017
A randomised controlled trial of paracetamol and ibuprofen with or without codeine or oxycodone as initial analgesia for adults with moderate pain from limb injury.
    Emergency medicine Australasia : EMA, 2016, Volume: 28, Issue:6

    Topics: Acetaminophen; Adult; Aged; Analgesia; Analgesics; Codeine; Double-Blind Method; Drug Therapy, Combi

2016
Intramuscular ketorolac versus oral ibuprofen in acute musculoskeletal pain.
    Annals of emergency medicine, 1995, Volume: 26, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal;

1995
Comparative tolerability of paracetamol, aspirin and ibuprofen for short-term analgesia in patients with musculoskeletal conditions: results in 4291 patients.
    Clinical rheumatology, 2002, Volume: 21, Issue:1

    Topics: Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Aspirin; Double-Blind Method; Female; Ga

2002

Other Studies

2 other studies available for ibuprofen and Orthopedic Disorders

ArticleYear
Effectiveness of ibuprofen plus paracetamol combination on persistence of acute musculoskeletal disorders in primary care patients.
    International journal of clinical pharmacy, 2021, Volume: 43, Issue:4

    Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Midd

2021
Optimal pain relief for pediatric MSK injury.
    Canadian family physician Medecin de famille canadien, 2015, Volume: 61, Issue:6

    Topics: Acetaminophen; Analgesics; Canada; Child; Codeine; Drug Combinations; Humans; Ibuprofen; Morphine; M

2015