Page last updated: 2024-10-28

ibuprofen and Odontalgia

ibuprofen has been researched along with Odontalgia in 32 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to evaluate the effect of oral ketamine on the dosage of local anesthetics required and postoperative pain management for irreversibly inflamed mandibular molars."6.76The effect of orally administered ketamine on requirement for anesthetics and postoperative pain in mandibular molar teeth with irreversible pulpitis. ( Ebtehaj, I; Kaviani, N; Khademi, A; Mohammadi, Z, 2011)
"Ibuprofen affected testing values for vital teeth by masking palpation 40%, percussion 25%, and cold 25% on affected teeth with symptomatic irreversible pulpitis and symptomatic apical periodontitis."5.19Effect of Ibuprofen on masking endodontic diagnosis. ( Bowles, WR; Khan, AA; Lunos, S; McClanahan, SB; Read, JK, 2014)
"The aim of this controlled clinical trial was to investigate the analgesic efficacy and tolerability of ibuprofen arginine in patients with mild-to-moderate periodontitis during and after non-surgical periodontal treatment."5.12Ibuprofen arginine for pain control during scaling and root planing: a randomized, triple-blind trial. ( Bernasconi, C; Bless, K; Ettlin, A; Ettlin, DA; Gallo, LM; Palla, S; Puhan, M; Tillmann, HC, 2006)
"The purpose of this prospective, double-blind, randomized study was to evaluate pain reduction using an intraosseous injection of slow-releasing methylprednisolone in teeth with irreversible pulpitis."5.09Pain reduction in untreated irreversible pulpitis using an intraosseous injection of Depo-Medrol. ( Beck, M; Gallatin, E; Nist, R; Reader, A, 2000)
"001 for both); efficacy was sustained over each of the four 12-hour dosing intervals with ibuprofen."2.84Analgesic Efficacy of a New Immediate-Release/Extended-Release Formulation of Ibuprofen: Results From Single- and Multiple-Dose Postsurgical Dental Pain Studies. ( Christensen, S; Daniels, S; Jayawardena, S; Meeves, S; Paluch, E, 2017)
"Each patient was asked to record their postoperative pain on a visual analogue scale with 4 categories at 6 hours, 12 hours, 18 hours, 1 day, and then daily for 6 days after this treatment."2.78Effect of occlusal reduction on postoperative pain in teeth with irreversible pulpitis and mild tenderness to percussion. ( Abbott, PV; Ashouri, R; Gorjestani, H; Nakhaee, N; Parirokh, M; Rekabi, AR, 2013)
" The aim of this study was to evaluate the effect of oral ketamine on the dosage of local anesthetics required and postoperative pain management for irreversibly inflamed mandibular molars."2.76The effect of orally administered ketamine on requirement for anesthetics and postoperative pain in mandibular molar teeth with irreversible pulpitis. ( Ebtehaj, I; Kaviani, N; Khademi, A; Mohammadi, Z, 2011)
"Tapentadol is a novel, centrally acting analgesic with two modes of action, combining mu-opioid agonism and norepinephrine reuptake inhibition in a single molecule."2.73Single dose analgesic efficacy of tapentadol in postsurgical dental pain: the results of a randomized, double-blind, placebo-controlled study. ( Black, P; Desjardins, P; Goldberg, J; Kleinert, R; Lange, C; Steup, A, 2008)
"Ibuprofen was the most studied NSAID."2.55Nonsteroidal Anti-inflammatory Drugs for Managing Postoperative Endodontic Pain in Patients Who Present with Preoperative Pain: A Systematic Review and Meta-analysis. ( Barker, DR; Marshall, JG; Sedgley, CM; Selph, SS; Smith, EA, 2017)
"001, respectively) and 60 min after dosing (p < 0."2.41The onset of action and the analgesic efficacy of Saridon (a propyphenazone/paracetamol/ caffeine combination) in comparison with paracetamol, ibuprofen, aspirin and placebo (pooled statistical analysis). ( Kiersch, TA; Minić, MR, 2002)
"Ibuprofen was the most frequently prescribed medication for pain, and penicillin was the most frequently prescribed antibiotic when an active infection was present."1.35Current trends in endodontic practice: emergency treatments and technological armamentarium. ( Caine, R; Hartwell, G; Lee, M; Stewart, J; Winkler, J, 2009)
"Pretreatment with morphine 30 min before pulp exposure dose-dependently (2."1.33Effects of pre-emptive morphine, ibuprofen or local anesthetic on fos expression in the spinal trigeminal nucleus following tooth pulp exposure in the rat. ( Erickson, TE; Gebhart, GF; Johnson, WT; Law, AS; Locher-Claus, MT, 2005)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (25.00)18.2507
2000's14 (43.75)29.6817
2010's10 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Taggar, T1
Wu, D1
Khan, AA2
Fedorowicz, Z2
van Zuuren, EJ2
Farman, AG2
Agnihotry, A2
Al-Langawi, JH2
Read, JK1
McClanahan, SB1
Lunos, S1
Bowles, WR2
Raoof, R1
Esmaeili-Mahani, S1
Abbasnejad, M1
Raoof, M1
Sheibani, V1
Kooshki, R1
Amirkhosravi, L1
Rafie, F1
Christensen, S1
Paluch, E1
Jayawardena, S2
Daniels, S1
Meeves, S1
Smith, EA1
Marshall, JG1
Selph, SS1
Barker, DR1
Sedgley, CM1
Kleinert, R1
Lange, C1
Steup, A1
Black, P1
Goldberg, J1
Desjardins, P2
Lee, M1
Winkler, J1
Hartwell, G1
Stewart, J1
Caine, R1
Li, H1
Mandema, J1
Wada, R1
Doyle, G1
Kellstein, D1
Kaviani, N1
Khademi, A1
Ebtehaj, I1
Mohammadi, Z1
Parirokh, M1
Rekabi, AR1
Ashouri, R1
Nakhaee, N1
Abbott, PV1
Gorjestani, H1
Dodd, MD2
Graham, CA1
Gopikrishna, V1
Parameswaran, A1
Al Aboud, K1
Ramesh, V1
Al Hawsawi, K1
Locher-Claus, MT1
Erickson, TE1
Law, AS1
Johnson, WT1
Gebhart, GF1
Ettlin, DA1
Ettlin, A1
Bless, K1
Puhan, M1
Bernasconi, C1
Tillmann, HC1
Palla, S1
Gallo, LM1
Mickel, AK1
Wright, AP1
Chogle, S1
Jones, JJ1
Kantorovich, I1
Curd, F1
Ryan, JL1
Jureidini, B1
Hodges, JS1
Baisden, M1
Swift, JQ1
Preshaw, PM1
Meechan, JG1
Torabinejad, M1
Cymerman, JJ1
Frankson, M1
Lemon, RR1
Maggio, JD1
Schilder, H1
Balevi, B1
Troullos, E1
Hargreaves, KM2
Dionne, RA1
Dionne, R2
Rogers, MJ1
Johnson, BR1
Remeikis, NA1
BeGole, EA1
Gallatin, E1
Reader, A1
Nist, R1
Beck, M1
Kiersch, TA1
Minić, MR1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Preoperative Single Dose of Sodium Ibuprofen Versus Placebo on Post-operative Pain for Patient With Symptomatic Irreversible Pulpitis Related to Mandibular Molar Teeth: Double Blind Randomized Controlled Trial[NCT04964622]Phase 1/Phase 250 participants (Actual)Interventional2021-12-01Completed
A Comparison of Analgesic and Respiratory Effects From Tapentadol Versus Oxycodone After Laparoscopic Hysterectomy.[NCT03314792]Phase 486 participants (Actual)Interventional2017-12-04Completed
Patient Perception Between Two Emergency Treatments of Symptomatic Irreversible Pulpitis. A Randomized Multicenter Clinical Trial.[NCT04654845]80 participants (Actual)Interventional2020-11-16Completed
Effect on Initial Endodontic Treatment on Postoperative Pain in Symptomatic Teeth With Pulpal Necrosis[NCT01870973]108 participants (Actual)Interventional2013-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Percent of Patients With Success as Defined by no or Mild Pain as Analyzed on a VAS Scale and no Narcotic Use

"pain measurement as assessed on a visual analog scale and pain medication usage~definition of success = no or mild pain as analyzed on VAS scale and no narcotic use; analyzed by logistic regression~VAS scale is 0 to 170 mm with the higher numbers indicating more pain and less success." (NCT01870973)
Timeframe: each day for 5 days

Interventionpercentage of participants (Number)
Root Canal Treatment52
no Root Canal Treatment43

Reviews

5 reviews available for ibuprofen and Odontalgia

ArticleYear
Antibiotic use for irreversible pulpitis.
    The Cochrane database of systematic reviews, 2013, Dec-19, Issue:12

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Humans; Ibuprofen; Pain Measurement;

2013
Antibiotic use for irreversible pulpitis.
    The Cochrane database of systematic reviews, 2016, Feb-17, Volume: 2

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Female; Humans; Ibuprofen; Ma

2016
Nonsteroidal Anti-inflammatory Drugs for Managing Postoperative Endodontic Pain in Patients Who Present with Preoperative Pain: A Systematic Review and Meta-analysis.
    Journal of endodontics, 2017, Volume: 43, Issue:1

    Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Naproxen; Pain

2017
Evidence-based review of clinical studies on pharmacology (non-anesthetic studies).
    Journal of endodontics, 2009, Volume: 35, Issue:8

    Topics: Acetaminophen; Administration, Oral; Analgesics; Anxiety; Dental Pulp Diseases; Dexamethasone; Drug

2009
The onset of action and the analgesic efficacy of Saridon (a propyphenazone/paracetamol/ caffeine combination) in comparison with paracetamol, ibuprofen, aspirin and placebo (pooled statistical analysis).
    Current medical research and opinion, 2002, Volume: 18, Issue:1

    Topics: Adult; Antipyrine; Aspirin; Caffeine; Double-Blind Method; Drug Combinations; Female; Humans; Ibupro

2002

Trials

14 trials available for ibuprofen and Odontalgia

ArticleYear
A Randomized Clinical Trial Comparing 2 Ibuprofen Formulations in Patients with Acute Odontogenic Pain.
    Journal of endodontics, 2017, Volume: 43, Issue:5

    Topics: Adult; Analgesics, Non-Narcotic; Double-Blind Method; Drug Compounding; Female; Humans; Ibuprofen; M

2017
Effect of Ibuprofen on masking endodontic diagnosis.
    Journal of endodontics, 2014, Volume: 40, Issue:8

    Topics: Adult; Aged; Analgesics, Non-Narcotic; Bite Force; Cold Temperature; Dental Pulp; Double-Blind Metho

2014
Analgesic Efficacy of a New Immediate-Release/Extended-Release Formulation of Ibuprofen: Results From Single- and Multiple-Dose Postsurgical Dental Pain Studies.
    Clinical pharmacology in drug development, 2017, Volume: 6, Issue:3

    Topics: Adolescent; Adult; Analgesics; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double

2017
Single dose analgesic efficacy of tapentadol in postsurgical dental pain: the results of a randomized, double-blind, placebo-controlled study.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:6

    Topics: Adult; Analgesics; Double-Blind Method; Female; Humans; Ibuprofen; Male; Morphine; Pain, Postoperati

2008
Modeling the onset and offset of dental pain relief by ibuprofen.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind M

2012
The effect of orally administered ketamine on requirement for anesthetics and postoperative pain in mandibular molar teeth with irreversible pulpitis.
    Journal of oral science, 2011, Volume: 53, Issue:4

    Topics: Adjuvants, Anesthesia; Administration, Oral; Adolescent; Adult; Analgesics; Anesthesia, Dental; Anes

2011
Effect of occlusal reduction on postoperative pain in teeth with irreversible pulpitis and mild tenderness to percussion.
    Journal of endodontics, 2013, Volume: 39, Issue:1

    Topics: Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Calcium Hydroxide; Dental

2013
Effectiveness of prophylactic use of rofecoxib in comparison with ibuprofen on postendodontic pain.
    Journal of endodontics, 2003, Volume: 29, Issue:1

    Topics: Acute Disease; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase

2003
Ibuprofen arginine for pain control during scaling and root planing: a randomized, triple-blind trial.
    Journal of clinical periodontology, 2006, Volume: 33, Issue:5

    Topics: Adult; Aged; Analgesics, Non-Narcotic; Arginine; Chronic Disease; Dental Scaling; Double-Blind Metho

2006
Gender differences in analgesia for endodontic pain.
    Journal of endodontics, 2008, Volume: 34, Issue:5

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Combinations; Female; Humans

2008
Effectiveness of various medications on postoperative pain following complete instrumentation.
    Journal of endodontics, 1994, Volume: 20, Issue:7

    Topics: Acetaminophen; Adult; Analysis of Variance; Chi-Square Distribution; Codeine; Dental Anxiety; Erythr

1994
Ibuprofen elevates immunoreactive beta-endorphin levels in humans during surgical stress.
    Clinical pharmacology and therapeutics, 1997, Volume: 62, Issue:1

    Topics: Adult; Analysis of Variance; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroi

1997
Comparison of effect of intracanal use of ketorolac tromethamine and dexamethasone with oral ibuprofen on post treatment endodontic pain.
    Journal of endodontics, 1999, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents; Anti-Inflammatory Agents, N

1999
Pain reduction in untreated irreversible pulpitis using an intraosseous injection of Depo-Medrol.
    Journal of endodontics, 2000, Volume: 26, Issue:11

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents; Anti-I

2000

Other Studies

13 other studies available for ibuprofen and Odontalgia

ArticleYear
Changes in hippocampal orexin 1 receptor expression involved in tooth pain-induced learning and memory impairment in rats.
    Neuropeptides, 2015, Volume: 50

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoxazoles; Capsaicin; Dental Pulp; Hippocampus;

2015
Current trends in endodontic practice: emergency treatments and technological armamentarium.
    Journal of endodontics, 2009, Volume: 35, Issue:1

    Topics: Analgesics; Anti-Bacterial Agents; Calcium Hydroxide; Diffusion of Innovation; Emergency Treatment;

2009
Unintentional overdose of analgesia secondary to acute dental pain.
    British dental journal, 2002, Aug-24, Volume: 193, Issue:4

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents,

2002
[Rapid, strong and long-term effectiveness. Coxib also effective in toothache].
    MMW Fortschritte der Medizin, 2003, Jan-16, Volume: 145, Issue:1-2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; C

2003
Fixed drug eruption to ibuprofen in daughter and father.
    Journal of drugs in dermatology : JDD, 2003, Volume: 2, Issue:6

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Drug Eruptions;

2003
Nonprescription dental pain relief.
    Dentistry today, 2004, Volume: 23, Issue:12

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations;

2004
Effects of pre-emptive morphine, ibuprofen or local anesthetic on fos expression in the spinal trigeminal nucleus following tooth pulp exposure in the rat.
    Journal of endodontics, 2005, Volume: 31, Issue:8

    Topics: Analgesics, Opioid; Analysis of Variance; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non

2005
An analysis of current analgesic preferences for endodontic pain management.
    Journal of endodontics, 2006, Volume: 32, Issue:12

    Topics: Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cross-Sectional Studies; Dr

2006
Self-medication for the control of dental pain: what are our patients taking?
    Dental update, 1994, Volume: 21, Issue:7

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Aspirin; Chi-Square Distribution; Codeine; Consu

1994
Ketorolac versus ibuprofen: a simple cost-efficacy comparison for dental use.
    Journal (Canadian Dental Association), 1994, Volume: 60, Issue:1

    Topics: Analgesics; Cost-Benefit Analysis; Humans; Ibuprofen; Ketorolac; Pain, Postoperative; Tolmetin; Toot

1994
Management of pain in endodontic patients.
    Texas dental journal, 1997, Volume: 114, Issue:10

    Topics: Acute Disease; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Dental Pulp Dis

1997
To tame the pain?
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 1998, Volume: 19, Issue:4

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Hydrocodone; Ibuprofen; Toothac

1998
COX-2 inhibitors: better than ibuprofen for dental pain?
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 1999, Volume: 20, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; C

1999