ibuprofen has been researched along with Neurodegenerative Diseases in 4 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Machado-Joseph disease or spinocerebellar ataxia type 3 is an inherited neurodegenerative disease associated with an abnormal glutamine over-repetition within the ataxin-3 protein." | 5.51 | Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado-Joseph disease models. ( Brinkhaus, M; Henriques, D; Kaspar, BK; Matos, C; Mendonça, LS; Moreira, R; Nóbrega, C; Pereira de Almeida, L; Tavino, S; Tomé, S, 2019) |
| "Ibuprofen was infused to steady-state concentrations both in plasma and brain tissue." | 5.33 | Inefficient central nervous system delivery limits the use of ibuprofen in neurodegenerative diseases. ( Järvinen, T; Lehtonen, M; Mannila, A; Rautio, J; Savolainen, J, 2005) |
| "Machado-Joseph disease or spinocerebellar ataxia type 3 is an inherited neurodegenerative disease associated with an abnormal glutamine over-repetition within the ataxin-3 protein." | 1.51 | Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado-Joseph disease models. ( Brinkhaus, M; Henriques, D; Kaspar, BK; Matos, C; Mendonça, LS; Moreira, R; Nóbrega, C; Pereira de Almeida, L; Tavino, S; Tomé, S, 2019) |
| "Ibuprofen is a widely used nonsteroidal anti-inflammatory drug that reportedly reduces the risk of Alzheimer's disease (AD) development." | 1.40 | Ibuprofen partially attenuates neurodegenerative symptoms in presenilin conditional double-knockout mice. ( Dong, Z; Huang, G; Mei, B; Meng, B; Yan, L; Zhang, L, 2014) |
| "Ibuprofen was infused to steady-state concentrations both in plasma and brain tissue." | 1.33 | Inefficient central nervous system delivery limits the use of ibuprofen in neurodegenerative diseases. ( Järvinen, T; Lehtonen, M; Mannila, A; Rautio, J; Savolainen, J, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cornec, AS | 1 |
| Monti, L | 1 |
| Kovalevich, J | 1 |
| Makani, V | 1 |
| James, MJ | 1 |
| Vijayendran, KG | 1 |
| Oukoloff, K | 1 |
| Yao, Y | 1 |
| Lee, VM | 1 |
| Trojanowski, JQ | 1 |
| Smith, AB | 1 |
| Brunden, KR | 1 |
| Ballatore, C | 1 |
| Mendonça, LS | 1 |
| Nóbrega, C | 1 |
| Tavino, S | 1 |
| Brinkhaus, M | 1 |
| Matos, C | 1 |
| Tomé, S | 1 |
| Moreira, R | 1 |
| Henriques, D | 1 |
| Kaspar, BK | 1 |
| Pereira de Almeida, L | 1 |
| Dong, Z | 1 |
| Yan, L | 1 |
| Huang, G | 1 |
| Zhang, L | 1 |
| Mei, B | 1 |
| Meng, B | 1 |
| Mannila, A | 1 |
| Rautio, J | 1 |
| Lehtonen, M | 1 |
| Järvinen, T | 1 |
| Savolainen, J | 1 |
4 other studies available for ibuprofen and Neurodegenerative Diseases
| Article | Year |
|---|---|
Multitargeted Imidazoles: Potential Therapeutic Leads for Alzheimer's and Other Neurodegenerative Diseases.
Topics: Alzheimer Disease; Animals; Arachidonate 5-Lipoxygenase; Chemistry Techniques, Synthetic; Cyclooxyge | 2017 |
Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado-Joseph disease models.
Topics: Animals; Ataxin-3; Cell Line, Tumor; Cell Proliferation; Cerebellum; Disease Models, Animal; Fibrobl | 2019 |
Ibuprofen partially attenuates neurodegenerative symptoms in presenilin conditional double-knockout mice.
Topics: Age Factors; Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Anti | 2014 |
Inefficient central nervous system delivery limits the use of ibuprofen in neurodegenerative diseases.
Topics: Animals; Central Nervous System; Drug Delivery Systems; Ibuprofen; Male; Neurodegenerative Diseases; | 2005 |