Page last updated: 2024-10-28

ibuprofen and Neuralgia

ibuprofen has been researched along with Neuralgia in 15 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

Research Excerpts

ExcerptRelevanceReference
"In a randomized, double-blind crossover study, 40 patients with postherpetic neuralgia were given single oral doses of clonidine, 0."9.06Association of pain relief with drug side effects in postherpetic neuralgia: a single-dose study of clonidine, codeine, ibuprofen, and placebo. ( Culnane, M; Dubner, R; Gracely, RH; Max, MB; Schafer, SC, 1988)
"In a randomized, double-blind crossover study, 40 patients with postherpetic neuralgia were given single oral doses of clonidine, 0."5.06Association of pain relief with drug side effects in postherpetic neuralgia: a single-dose study of clonidine, codeine, ibuprofen, and placebo. ( Culnane, M; Dubner, R; Gracely, RH; Max, MB; Schafer, SC, 1988)
" In patients with neuropathic pain, topical forms of both capsaicin and lidocaine have been shown to be useful in the treatment of postherpetic neuralgia and diabetic peripheral neuropathic pain."4.89Topical therapies in the management of chronic pain. ( Galluzzi, KE; Stanos, SP, 2013)
"Ibuprofen was consistently better than acetaminophen at 1 hour after treatment for relief of perineal pain after childbirth without any side effects."2.73Ibuprofen versus acetaminophen for the relief of perineal pain after childbirth: a randomized controlled trial. ( Kamondetdecha, R; Tannirandorn, Y, 2008)
"Ibuprofen arginate is a highly soluble salt formed by combining racemic ibuprofen with the amino acid l-arginine."1.38Comparison of the antinociceptive effects of ibuprofen arginate and ibuprofen in rat models of inflammatory and neuropathic pain. ( Berrocoso, E; Leza, JC; Mico, JA; Ortega-Álvaro, A; Rey-Brea, R, 2012)
"R(-)-ibuprofen or vehicle were without effect."1.32Spinal nerve injury activates prostaglandin synthesis in the spinal cord that contributes to early maintenance of tactile allodynia. ( Carter, P; Haley, M; Hefferan, MP; Loomis, CW, 2003)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's0 (0.00)18.2507
2000's5 (33.33)29.6817
2010's8 (53.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Yamaguchi, C1
Yamamoto, D1
Fujimaru, Y1
Asano, T1
Takaoka, A1
Micheli, L1
Ghelardini, C1
Lucarini, E1
Parisio, C1
Trallori, E1
Cinci, L1
Di Cesare Mannelli, L1
Tamaki, A1
Thuener, J1
Weidenbecher, M1
Krøigård, T1
Metaxas, A1
Wirenfeldt, M1
Finsen, B1
Kalliomäki, J1
Attal, N1
Jonzon, B1
Bach, FW1
Huizar, K1
Ratcliffe, S1
Eriksson, B1
Janecki, M1
Danilov, A1
Bouhassira, D1
Redondo-Castro, E1
Navarro, X1
Stanos, SP1
Galluzzi, KE1
Kopp, MA1
Liebscher, T1
Watzlawick, R1
Martus, P1
Laufer, S1
Blex, C1
Schindler, R1
Jungehulsing, GJ1
Knüppel, S1
Kreutzträger, M1
Ekkernkamp, A1
Dirnagl, U1
Strittmatter, SM1
Niedeggen, A1
Schwab, JM1
Kamondetdecha, R1
Tannirandorn, Y1
Fanucci, E1
Manenti, G1
Ursone, A1
Fusco, N1
Mylonakou, I1
D'Urso, S1
Simonetti, G1
Beldon, P1
Ortega-Álvaro, A1
Berrocoso, E1
Rey-Brea, R1
Leza, JC1
Mico, JA1
Herr, H1
Hefferan, MP1
Carter, P1
Haley, M1
Loomis, CW1
Max, MB1
Schafer, SC1
Culnane, M1
Dubner, R1
Gracely, RH1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
EN20-01: A 24 Week Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Moderate to Severe Knee Osteoarthritis Pain.[NCT05025787]Phase 277 participants (Anticipated)Interventional2021-10-25Recruiting
Trial Evaluating multimOdal toPical Cream In CompArison to pLacebo (TOPICAL)[NCT03199417]Phase 2/Phase 350 participants (Actual)Interventional2017-05-01Terminated (stopped due to Terminated prematurely due to feasibility issues with rate of recruitment)
The Rho-Inhibitor Ibuprofen for the Treatment of Acute Spinal Cord Injury: Investigation of Safety, Feasibility and Pharmacokinetics[NCT02096913]Phase 112 participants (Actual)Interventional2013-06-30Completed
Comparison of Ultrasound-guided Transgluteal and Finger-guided Transvaginal Pudendal Nerve Block Techniques: Which One is More Effective?[NCT03973983]40 participants (Actual)Interventional2016-11-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for ibuprofen and Neuralgia

ArticleYear
Superior Laryngeal Nerve Neuralgia: Case Series and Review of Anterior Neck Pain Syndromes.
    Ear, nose, & throat journal, 2019, Volume: 98, Issue:8

    Topics: Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal;

2019
Topical therapies in the management of chronic pain.
    Postgraduate medicine, 2013, Volume: 125, Issue:4 Suppl 1

    Topics: Administration, Cutaneous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; C

2013
Role of interventional radiology in pudendal neuralgia: a description of techniques and review of the literature.
    La Radiologia medica, 2009, Volume: 114, Issue:3

    Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents; Anticonvulsants; Antidepressive Agents; Female

2009
Topical dressings to manage pain in venous leg ulceration.
    British journal of community nursing, 2009, Volume: 14, Issue:3

    Topics: Administration, Topical; Analgesics, Opioid; Bandages; Bandages, Hydrocolloid; Humans; Ibuprofen; Ne

2009

Trials

4 trials available for ibuprofen and Neuralgia

ArticleYear
A randomized, double-blind, placebo-controlled trial of a chemokine receptor 2 (CCR2) antagonist in posttraumatic neuralgia.
    Pain, 2013, Volume: 154, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response R

2013
SCISSOR-Spinal Cord Injury Study on Small molecule-derived Rho inhibition: a clinical study protocol.
    BMJ open, 2016, 07-26, Volume: 6, Issue:7

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Gastrointestinal Hemorrhag

2016
Ibuprofen versus acetaminophen for the relief of perineal pain after childbirth: a randomized controlled trial.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2008, Volume: 91, Issue:3

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Episiotomy;

2008
Association of pain relief with drug side effects in postherpetic neuralgia: a single-dose study of clonidine, codeine, ibuprofen, and placebo.
    Clinical pharmacology and therapeutics, 1988, Volume: 43, Issue:4

    Topics: Aged; Aged, 80 and over; Clinical Trials as Topic; Clonidine; Codeine; Double-Blind Method; Female;

1988

Other Studies

7 other studies available for ibuprofen and Neuralgia

ArticleYear
Acetaminophen Exerts an Analgesic Effect on Muscular Hyperalgesia in Repeated Cold-Stressed Rats through the Enhancement of the Descending Pain Inhibitory System Involving Spinal 5-HT
    Biological & pharmaceutical bulletin, 2021, Aug-01, Volume: 44, Issue:8

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Cold Temperature; Cold-Shock Response; Cyclooxygen

2021
Intra-articular mucilages: behavioural and histological evaluations for a new model of articular pain.
    The Journal of pharmacy and pharmacology, 2019, Volume: 71, Issue:6

    Topics: Althaea; Analgesics; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Flax; Freund's Adjuvan

2019
Protective effect of ibuprofen in a rat model of chronic oxaliplatin-induced peripheral neuropathy.
    Experimental brain research, 2019, Volume: 237, Issue:10

    Topics: Animals; Antineoplastic Agents; Cytokines; Disease Models, Animal; Ganglia, Spinal; Ibuprofen; Infla

2019
Chronic ibuprofen administration reduces neuropathic pain but does not exert neuroprotection after spinal cord injury in adult rats.
    Experimental neurology, 2014, Volume: 252

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium-Binding Proteins; Evoked Potentials, Motor

2014
Comparison of the antinociceptive effects of ibuprofen arginate and ibuprofen in rat models of inflammatory and neuropathic pain.
    Life sciences, 2012, Jan-02, Volume: 90, Issue:1-2

    Topics: Analgesics, Non-Narcotic; Animals; Arginine; Cold Temperature; Disease Models, Animal; Drug Combinat

2012
Prognostic factors of postherpetic neuralgia.
    Journal of Korean medical science, 2002, Volume: 17, Issue:5

    Topics: Acyclovir; Adolescent; Adult; Aged; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Antidepr

2002
Spinal nerve injury activates prostaglandin synthesis in the spinal cord that contributes to early maintenance of tactile allodynia.
    Pain, 2003, Volume: 101, Issue:1-2

    Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors;

2003