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ibuprofen and Myocardial Ischemia

ibuprofen has been researched along with Myocardial Ischemia in 8 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

Research Excerpts

ExcerptRelevanceReference
"We performed a placebo-controlled, randomized study to address whether celecoxib or ibuprofen undermines the functional range of inhibition of platelet cyclooxygenase (COX)-1 activity by aspirin in patients with osteoarthritis and stable ischemic heart disease."9.12Celecoxib, ibuprofen, and the antiplatelet effect of aspirin in patients with osteoarthritis and ischemic heart disease. ( Capone, ML; D'Amelio, E; De Caterina, R; Grana, M; Patrignani, P; Patrono, C; Price, TS; Renda, G; Sacchetta, D; Santarelli, F; Sciulli, MG; Tacconelli, S; Zimarino, M; Zurro, M, 2006)
"A patient with Kawasaki disease is reported who had a medium-sized CAA prematurely occluded with thrombi during regression, resulting in myocardial ischemia."5.35Accelerated thrombotic occlusion of a medium-sized coronary aneurysm in Kawasaki disease by the inhibitory effect of ibuprofen on aspirin. ( Kwon, K; Sohn, S, 2008)
"We measured the urinary excretion of ATL in 24 patients with both ischaemic heart disease and osteoarthritis, chronically treated with aspirin and co-administered celecoxib 200 mg b."5.14Aspirin-triggered lipoxin in patients treated with aspirin and selective vs. nonselective COX-2 inhibitors. ( De Caterina, R; Renda, G; Romano, M; Zurro, M, 2010)
"We performed a placebo-controlled, randomized study to address whether celecoxib or ibuprofen undermines the functional range of inhibition of platelet cyclooxygenase (COX)-1 activity by aspirin in patients with osteoarthritis and stable ischemic heart disease."5.12Celecoxib, ibuprofen, and the antiplatelet effect of aspirin in patients with osteoarthritis and ischemic heart disease. ( Capone, ML; D'Amelio, E; De Caterina, R; Grana, M; Patrignani, P; Patrono, C; Price, TS; Renda, G; Sacchetta, D; Santarelli, F; Sciulli, MG; Tacconelli, S; Zimarino, M; Zurro, M, 2006)
"Patients suffering an acute myocardial infarction routinely receive morphine and nonsteroidal anti-inflammatory drugs (NSAIDs) alone or in combination."3.72Acute aspirin treatment abolishes, whereas acute ibuprofen treatment enhances morphine-induced cardioprotection: role of 12-lipoxygenase. ( Gross, ER; Gross, GJ; Hsu, AK, 2004)
"A patient with Kawasaki disease is reported who had a medium-sized CAA prematurely occluded with thrombi during regression, resulting in myocardial ischemia."1.35Accelerated thrombotic occlusion of a medium-sized coronary aneurysm in Kawasaki disease by the inhibitory effect of ibuprofen on aspirin. ( Kwon, K; Sohn, S, 2008)
"1."1.29Dissociation of the anti-ischaemic effects of cloricromene from its anti-platelet activity. ( Cirillo, R; Lidbury, PS; Vane, JR, 1993)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's6 (75.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Renda, G2
Zurro, M2
Romano, M1
De Caterina, R2
Gross, ER1
Hsu, AK1
Gross, GJ1
Saeed, SA1
Waqar, MA1
Zubairi, AJ1
Bhurgri, H1
Khan, A1
Gowani, SA1
Waqar, SN1
Choudhary, MI1
Jalil, S1
Zaidi, AH1
Ara, I1
Kofidis, T1
Lebl, DR1
Swijnenburg, RJ1
Greeve, JM1
Klima, U1
Gold, J1
Xu, C1
Robbins, RC1
Tacconelli, S1
Capone, ML1
Sacchetta, D1
Santarelli, F1
Sciulli, MG1
Zimarino, M1
Grana, M1
D'Amelio, E1
Price, TS1
Patrono, C1
Patrignani, P1
Gurfinkel, EP1
Guerlloy, FP1
Mautner, B1
Sohn, S1
Kwon, K1
Lidbury, PS1
Cirillo, R1
Vane, JR1

Reviews

1 review available for ibuprofen and Myocardial Ischemia

ArticleYear
Myocardial ischaemia and reperfusion injury: reactive oxygen species and the role of neutrophil.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2005, Volume: 15, Issue:8

    Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Epoprostenol; Free Radical Scavengers; Humans;

2005

Trials

2 trials available for ibuprofen and Myocardial Ischemia

ArticleYear
Aspirin-triggered lipoxin in patients treated with aspirin and selective vs. nonselective COX-2 inhibitors.
    British journal of clinical pharmacology, 2010, Volume: 69, Issue:3

    Topics: Aged; Aspirin; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Humans; Ibuprofen;

2010
Celecoxib, ibuprofen, and the antiplatelet effect of aspirin in patients with osteoarthritis and ischemic heart disease.
    Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:3

    Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Celecoxib; Double-Blind Method; Drug Adminis

2006

Other Studies

5 other studies available for ibuprofen and Myocardial Ischemia

ArticleYear
Acute aspirin treatment abolishes, whereas acute ibuprofen treatment enhances morphine-induced cardioprotection: role of 12-lipoxygenase.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 310, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 12-Lipoxygenase; Aspirin; Blood Press

2004
Allopurinol/uricase and ibuprofen enhance engraftment of cardiomyocyte-enriched human embryonic stem cells and improve cardiac function following myocardial injury.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2006, Volume: 29, Issue:1

    Topics: Acute Disease; Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Combi

2006
Suppression of life-threatening tachyarrhyhmias, and atrio-ventricular ischemic block following the administration of anti-inflammatory intravenous drug.
    International journal of cardiology, 2007, Jan-08, Volume: 114, Issue:2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Emergencies; Female; Heart Block; Humans; Ibuprofen;

2007
Accelerated thrombotic occlusion of a medium-sized coronary aneurysm in Kawasaki disease by the inhibitory effect of ibuprofen on aspirin.
    Pediatric cardiology, 2008, Volume: 29, Issue:1

    Topics: Aspirin; Child; Coronary Occlusion; Coronary Thrombosis; Coronary Vessels; Drug Interactions; Heart;

2008
Dissociation of the anti-ischaemic effects of cloricromene from its anti-platelet activity.
    British journal of pharmacology, 1993, Volume: 110, Issue:1

    Topics: Animals; Blood Pressure; Chromonar; Coronary Vessels; Electrocardiography; Heart Rate; Ibuprofen; In

1993