ibuprofen has been researched along with Muscle Contraction in 39 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These data indicate that a prophylactic dosage of ibuprofen does not prevent CK release from muscle, but does decrease muscle soreness perception and may assist in restoring muscle function." | 2.67 | Effect of ibuprofen use on muscle soreness, damage, and performance: a preliminary investigation. ( Daniels, JC; Divine, JG; Hasson, SM; Niebuhr, BR; Richmond, S; Stein, PG; Williams, JH, 1993) |
| "Fatigue was felt in the masseter muscle after about 30 seconds of MVC; differential calculus suggested that the appearance and disappearance of fatigue was associated with primarily recruitment and decruitment of masseteric motor units, respectively." | 2.38 | Experimental teeth clenching in man. ( Christensen, LV, 1989) |
| "Ibuprofen treatment prevented sustained elevation of MEK-ERK signaling at 3 h (p-ERK1/2, p-RSK, p-Mnk1, p-p70S6K Thr421/Ser424) and 24 h (p-ERK1/2) postexercise, and this was associated with suppressed phosphorylation of ribosomal protein S6 (Ser235/236 and Ser240/244)." | 1.40 | Ibuprofen treatment blunts early translational signaling responses in human skeletal muscle following resistance exercise. ( Cameron-Smith, D; Figueiredo, VC; Markworth, JF; Vella, LD, 2014) |
| "Pravadoline was also inhibitory in the MVD." | 1.28 | Antinociceptive (aminoalkyl)indoles. ( Bell, MR; D'Ambra, TE; Daum, SJ; Eissenstat, MA; Herrmann, JL; Hlasta, DJ; Kumar, V; Philion, RE; Rosi, D; Wetzel, JR, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (38.46) | 18.7374 |
| 1990's | 10 (25.64) | 18.2507 |
| 2000's | 9 (23.08) | 29.6817 |
| 2010's | 4 (10.26) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Bell, MR | 1 |
| D'Ambra, TE | 1 |
| Kumar, V | 1 |
| Eissenstat, MA | 1 |
| Herrmann, JL | 1 |
| Wetzel, JR | 1 |
| Rosi, D | 1 |
| Philion, RE | 1 |
| Daum, SJ | 1 |
| Hlasta, DJ | 1 |
| Musser, JH | 1 |
| Kreft, AF | 1 |
| Bender, RH | 1 |
| Kubrak, DM | 1 |
| Grimes, D | 1 |
| Carlson, RP | 1 |
| Hand, JM | 1 |
| Chang, J | 1 |
| Habeeb, AG | 1 |
| Praveen Rao, PN | 1 |
| Knaus, EE | 1 |
| Nikaido, T | 1 |
| Muroga, S | 1 |
| Maruyama, C | 1 |
| Fujimaru, Y | 1 |
| Asano, T | 1 |
| Takaoka, A | 1 |
| West, EG | 1 |
| Lang, R | 1 |
| Sellers, D | 1 |
| Chess-Williams, R | 1 |
| McDermott, C | 1 |
| Morgan, PT | 1 |
| Vanhatalo, A | 1 |
| Bowtell, JL | 1 |
| Jones, AM | 1 |
| Bailey, SJ | 1 |
| Markworth, JF | 1 |
| Vella, LD | 1 |
| Figueiredo, VC | 1 |
| Cameron-Smith, D | 1 |
| Dideriksen, K | 1 |
| Boesen, AP | 1 |
| Kristiansen, JF | 1 |
| Magnusson, SP | 1 |
| Schjerling, P | 1 |
| Holm, L | 1 |
| Kjaer, M | 1 |
| Collins, C | 1 |
| Klausner, AP | 1 |
| Herrick, B | 1 |
| Koo, HP | 1 |
| Miner, AS | 1 |
| Henderson, SC | 1 |
| Ratz, PH | 1 |
| El Sayah, M | 1 |
| Calixto, JB | 2 |
| Tokmakidis, SP | 1 |
| Kokkinidis, EA | 1 |
| Smilios, I | 1 |
| Douda, H | 1 |
| Maslow, KD | 1 |
| Lyons, EA | 1 |
| Rahnama, N | 1 |
| Rahmani-Nia, F | 1 |
| Ebrahim, K | 1 |
| Downie, JW | 1 |
| Karmazyn, M | 1 |
| Aiken, JW | 1 |
| Shebuski, RJ | 1 |
| Gorman, RR | 1 |
| Diamond, S | 1 |
| Cabrini, DA | 1 |
| Silva, AM | 1 |
| Greenberg, S | 1 |
| Xie, J | 1 |
| Wang, Y | 1 |
| Cai, B | 1 |
| Kolls, J | 1 |
| Nelson, S | 1 |
| Hyman, A | 1 |
| Summer, WR | 1 |
| Lippton, H | 1 |
| Hasson, SM | 1 |
| Daniels, JC | 1 |
| Divine, JG | 1 |
| Niebuhr, BR | 1 |
| Richmond, S | 1 |
| Stein, PG | 1 |
| Williams, JH | 1 |
| Bole-Vunduk, B | 1 |
| Verhnjak, K | 1 |
| Zmitek, J | 1 |
| Svensson, P | 1 |
| Houe, L | 1 |
| Arendt-Nielsen, L | 1 |
| Bolle, P | 1 |
| Fidanza, S | 1 |
| Tucci, P | 1 |
| Sim, SS | 1 |
| Choi, JC | 1 |
| Min, DS | 1 |
| Rhie, DJ | 1 |
| Yoon, SH | 1 |
| Hahn, SJ | 1 |
| Kim, CJ | 1 |
| Kim, MS | 1 |
| Jo, YH | 1 |
| Sangha, DS | 1 |
| Han, S | 1 |
| Purdy, RE | 1 |
| Downing, SJ | 1 |
| Tay, JI | 1 |
| Maguiness, SD | 1 |
| Watson, A | 1 |
| Leese, HJ | 1 |
| Wilhelm, PB | 1 |
| Alphen, GW | 1 |
| Ryan, RE | 1 |
| Coceani, F | 1 |
| Olley, PM | 1 |
| Bishai, I | 1 |
| Bodach, E | 1 |
| Heaton, J | 1 |
| Nashat, M | 1 |
| White, E | 1 |
| Guyonnet, JC | 1 |
| Julou, L | 1 |
| Patterson, CE | 1 |
| Jin, N | 1 |
| Packer, CS | 1 |
| Rhoades, RA | 1 |
| Gray, DW | 1 |
| Marshall, I | 1 |
| Ritter, JM | 1 |
| Doktor, HS | 1 |
| Cragoe, EJ | 1 |
| Christensen, LV | 1 |
| Schachtel, BP | 1 |
| Thoden, WR | 1 |
| Helliwell, PS | 1 |
| Howe, A | 1 |
| Wright, V | 1 |
| Itoh, H | 1 |
| Muramatsu, I | 1 |
| Patel, P | 1 |
| Lederis, K | 1 |
| Hollenberg, MD | 1 |
| Carlsson, I | 1 |
| Sollevi, A | 1 |
| Wennmalm, A | 1 |
| Friedman, MH | 1 |
| Voelkel, NF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Liberal Versus Restrictive Platelet Transfusion for Treatment of Hemodynamically Significant Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates- A Randomized Open Label, Controlled Trial[NCT03022253] | Phase 3 | 44 participants (Anticipated) | Interventional | 2016-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for ibuprofen and Muscle Contraction
| Article | Year |
|---|---|
Experimental teeth clenching in man.
Topics: Cryotherapy; Dental Occlusion, Centric; Electromyography; Facial Pain; Fatigue; Humans; Ibuprofen; I | 1989 |
Species variations in the pulmonary responses to arachidonic acid metabolites.
Topics: Airway Resistance; Animals; Animals, Newborn; Arachidonic Acids; Bronchi; Child; Fetus; Humans; Ibup | 1985 |
8 trials available for ibuprofen and Muscle Contraction
| Article | Year |
|---|---|
Skeletal muscle adaptation to immobilization and subsequent retraining in elderly men: No effect of anti-inflammatory medication.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Denmark; Double-Blind Method; Gene | 2016 |
The effects of ibuprofen on delayed muscle soreness and muscular performance after eccentric exercise.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Creatine Kinase; Double-Blind Method; Exercise; Fema | 2003 |
Effect of prostaglandin and antiprostaglandin on midcycle myometrial contractions.
Topics: Adolescent; Adult; Cyclooxygenase Inhibitors; Dinoprostone; Female; Humans; Ibuprofen; Menstrual Cyc | 2004 |
The isolated and combined effects of selected physical activity and ibuprofen on delayed-onset muscle soreness.
Topics: Adult; Analgesics, Non-Narcotic; Athletic Injuries; Combined Modality Therapy; Creatine Kinase; Elbo | 2005 |
Ibuprofen versus aspirin and placebo in the treatment of muscle contraction headache.
Topics: Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Headache; Humans; Ibuprofen; | 1983 |
Effect of ibuprofen use on muscle soreness, damage, and performance: a preliminary investigation.
Topics: Adolescent; Adult; Biomechanical Phenomena; Creatine Kinase; Double-Blind Method; Electromyography; | 1993 |
Effect of systemic versus topical nonsteroidal anti-inflammatory drugs on postexercise jaw-muscle soreness: a placebo-controlled study.
Topics: Administration, Oral; Administration, Topical; Adult; Analysis of Variance; Anti-Inflammatory Agents | 1997 |
Onset of action of ibuprofen in the treatment of muscle-contraction headache.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Headache; Humans; Ibuprofen; Muscl | 1988 |
29 other studies available for ibuprofen and Muscle Contraction
| Article | Year |
|---|---|
Antinociceptive (aminoalkyl)indoles.
Topics: Analgesia; Analgesics; Animals; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Indoles; M | 1991 |
N-[(arylmethoxy)phenyl] carboxylic acids, hydroxamic acids, tetrazoles, and sulfonyl carboxamides. Potent orally active leukotriene D4 antagonists of novel structure.
Topics: Animals; Azoles; Benzamides; Biological Assay; Bronchial Spasm; Carrageenan; Chemical Phenomena; Che | 1990 |
Design and synthesis of 4,5-diphenyl-4-isoxazolines: novel inhibitors of cyclooxygenase-2 with analgesic and antiinflammatory activity.
Topics: Abdominal Muscles; Androstenols; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cycl | 2001 |
Ethenzamide Exerts Protective Effects against Ibuprofen-Induced Gastric Mucosal Damage in Rats by Suppressing Gastric Contraction.
Topics: Acetylcholine; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ibuprofen | 2021 |
Ibuprofen Decreases Spontaneous Activity and Enhances Nerve-Evoked Contractions to Minimize Mitomycin C-Induced Bladder Dysfunction.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Cell Line, Tumor; Female; Humans; Ibuprofen; Mice; M | 2018 |
Acute ibuprofen ingestion does not attenuate fatigue during maximal intermittent knee extensor or all-out cycling exercise.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Bicycling; Electric Stimulation; Electromyography; E | 2019 |
Ibuprofen treatment blunts early translational signaling responses in human skeletal muscle following resistance exercise.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Exercise; Humans | 2014 |
Potential for control of detrusor smooth muscle spontaneous rhythmic contraction by cyclooxygenase products released by interstitial cells of Cajal.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Hydrazines; Ibuprofe | 2009 |
Study of the mechanisms involved in the bradykinin-induced contraction of the pig iris sphincter muscle in vitro.
Topics: Animals; Atropine; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Dose-Resp | 2003 |
Mechanical trauma to bladder epithelium liberates prostanoids which modulate neurotransmission in rabbit detrusor muscle.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bethanechol; Bethanechol Compounds; Carbachol; Dose-Response | 1984 |
Blockage of partially obstructed coronary arteries with platelet thrombi: comparison between its prevention with cyclooxygenase inhibitors versus prostacyclin.
Topics: Animals; Aorta; Arachidonic Acids; Aspirin; Coronary Vessels; Cyclic AMP; Cyclooxygenase Inhibitors; | 1980 |
Mechanisms of bradykinin-induced contraction of the guinea-pig gallbladder in vitro.
Topics: Animals; Bradykinin; Dinoprostone; Dose-Response Relationship, Drug; Female; Gallbladder; Guinea Pig | 1995 |
Tumor necrosis factor-alpha inhibits endothelium-dependent relaxation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine | 1993 |
Anti-inflammatory, analgesic and ulcerogenic properties of S-(+)-ibuproxam, racemic ibuproxam-beta-cyclodextrin and S-(+)-ibuproxam-beta-cyclodextrin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; beta-Cyclodextrins; Cyclodextri | 1996 |
Response to isoprenaline of rabbit detrusor muscle following exposure to 5, 8, 11, 14 eicosatetraynoic acid. Role of prostanoids on beta-adrenergic-evoked response.
Topics: Alprostadil; Animals; Arachidonic Acids; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; | 1999 |
The involvement of phospholipase A(2) in ethanol-induced gastric muscle contraction.
Topics: Animals; Cats; Central Nervous System Depressants; Cyclooxygenase Inhibitors; Dose-Response Relation | 2001 |
Simulated microgravity upregulates an endothelial vasoconstrictor prostaglandin.
Topics: Analysis of Variance; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carotid Arteries; Cyclooxyge | 2001 |
Effect of inflammatory mediators on the physiology of the human Fallopian tube.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Diclofenac; Dose-Response Relatio | 2002 |
Potentiation of PG effects on the intraocular muscles of the cat by inhibition of PG synthesis.
Topics: Animals; Cats; Ciliary Body; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Syner | 1977 |
Motrin--a new agent for the symptomatic treatment of muscle contraction headache.
Topics: Adult; Aged; Headache; Humans; Ibuprofen; Middle Aged; Muscle Contraction; Phenylpropionates | 1977 |
Prostaglandins and the control of muscle tone in the ductus arteriosus.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Ductus Arteriosus; Gestational Age; Glu | 1977 |
Relationship between the inhibitory activity on 'RCS' and prostaglandins synthesis and the anti-inflammatory activity of ketoprofen and several other non-steroidal anti-inflammatory agents.
Topics: Abscess; Animals; Anti-Inflammatory Agents; Aorta; Arachidonic Acids; Aspirin; Benzophenones; Colon; | 1976 |
Activated neutrophils alter contractile properties of the pulmonary artery.
Topics: Animals; Catalase; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Methacrylates; Muscle Contrac | 1992 |
Nitric oxide synthesis inhibitors attenuate calcitonin gene-related peptide endothelium-dependent vasorelaxation in rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Calcitonin Gene-Related Peptide; Endothelium, Vas | 1992 |
Actions of bradykinin and related peptides on rabbit coeliac artery rings.
Topics: Animals; Bradykinin; Celiac Artery; Ibuprofen; In Vitro Techniques; Methacholine Chloride; Methachol | 1989 |
An evaluation of the dynamic qualities of isometric grip strength.
Topics: Arthroplasty; Hand; Humans; Ibuprofen; Isometric Contraction; Muscle Contraction; Muscles; Physical | 1988 |
Inhibition by anti-inflammatory agents of contraction induced by epidermal growth factor-urogastrone in isolated longitudinal smooth muscle strips from guinea-pig stomach.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Auranofin; Cycloheximide; Dexamethasone; | 1988 |
The role of myogenic relaxation, adenosine and prostaglandins in human forearm reactive hyperaemia.
Topics: Adenosine; Adult; Arteries; Constriction; Female; Forearm; Humans; Ibuprofen; Male; Muscle Contracti | 1987 |
Tenomyositis of the masseter muscle: report of cases.
Topics: Adult; Anti-Inflammatory Agents; Female; Humans; Ibuprofen; Male; Masseter Muscle; Masticatory Muscl | 1985 |