ibuprofen has been researched along with Machado-Joseph Disease in 1 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Machado-Joseph Disease: A dominantly-inherited ATAXIA first described in people of Azorean and Portuguese descent, and subsequently identified in Brazil, Japan, China, and Australia. This disorder is classified as one of the SPINOCEREBELLAR ATAXIAS (Type 3) and has been associated with a mutation of the MJD1 gene on chromosome 14. Clinical features include progressive ataxia, DYSARTHRIA, postural instability, nystagmus, eyelid retraction, and facial FASCICULATIONS. DYSTONIA is prominent in younger patients (referred to as Type I Machado-Joseph Disease). Type II features ataxia and ocular signs; Type III features MUSCULAR ATROPHY and a sensorimotor neuropathy; and Type IV features extrapyramidal signs combined with a sensorimotor neuropathy. (From Clin Neurosci 1995;3(1):17-22; Ann Neurol 1998 Mar;43(3):288-96)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Machado-Joseph disease or spinocerebellar ataxia type 3 is an inherited neurodegenerative disease associated with an abnormal glutamine over-repetition within the ataxin-3 protein." | 5.51 | Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado-Joseph disease models. ( Brinkhaus, M; Henriques, D; Kaspar, BK; Matos, C; Mendonça, LS; Moreira, R; Nóbrega, C; Pereira de Almeida, L; Tavino, S; Tomé, S, 2019) |
| "Machado-Joseph disease or spinocerebellar ataxia type 3 is an inherited neurodegenerative disease associated with an abnormal glutamine over-repetition within the ataxin-3 protein." | 1.51 | Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado-Joseph disease models. ( Brinkhaus, M; Henriques, D; Kaspar, BK; Matos, C; Mendonça, LS; Moreira, R; Nóbrega, C; Pereira de Almeida, L; Tavino, S; Tomé, S, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mendonça, LS | 1 |
| Nóbrega, C | 1 |
| Tavino, S | 1 |
| Brinkhaus, M | 1 |
| Matos, C | 1 |
| Tomé, S | 1 |
| Moreira, R | 1 |
| Henriques, D | 1 |
| Kaspar, BK | 1 |
| Pereira de Almeida, L | 1 |
1 other study available for ibuprofen and Machado-Joseph Disease
| Article | Year |
|---|---|
Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado-Joseph disease models.
Topics: Animals; Ataxin-3; Cell Line, Tumor; Cell Proliferation; Cerebellum; Disease Models, Animal; Fibrobl | 2019 |