ibuprofen has been researched along with Low Back Pain in 22 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Low Back Pain: Acute or chronic pain in the lumbar or sacral regions, which may be associated with musculo-ligamentous SPRAINS AND STRAINS; INTERVERTEBRAL DISK DISPLACEMENT; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study seeks to compare the efficacy of intravenously administered paracetamol, dexketoprofen, and ibuprofen in patients with non-traumatic acute low back pain." | 9.51 | Comparative evaluation of the effectiveness of intravenous paracetamol, dexketoprofen and ibuprofen in acute low back pain. ( Dogan, C; Kemanci, A; Oskay, A; Ozen, M; Seyit, M; Turkcuer, I; Uluturk, M; Yilmaz, A, 2022) |
| "To assess the analgesic efficacy and safety of single-dose oral cannabidiol (CBD) as an adjunct to standard care for patients presenting to an emergency department with acute low back pain." | 9.41 | The CANBACK trial: a randomised, controlled clinical trial of oral cannabidiol for people presenting to the emergency department with acute low back pain. ( Bebee, B; Bourke, E; Ching, M; Foster, L; Pollack, K; Taylor, DM; Wong, A, 2021) |
| "Adding baclofen, metaxalone, or tizanidine to ibuprofen does not appear to improve functioning or pain any more than placebo plus ibuprofen by 1 week after an ED visit for acute low back pain." | 9.30 | A Randomized, Placebo-Controlled Trial of Ibuprofen Plus Metaxalone, Tizanidine, or Baclofen for Acute Low Back Pain. ( Friedman, BW; Gallagher, EJ; Irizarry, E; Jones, MP; Pearlman, S; Shah, PD; Solorzano, C; Wollowitz, A; Zias, E, 2019) |
| "Patients with chronic low back pain were randomly divided into 2 groups treated either with oral ibuprofen-arginine (400 mg) or with placebo." | 9.12 | Influence of ibuprofen-arginine on serum levels of nitric oxide metabolites in patients with chronic low back pain--a single-blind, placebo controlled pilot trial (ISRCTN18723747). ( Gay, RE; Gay, S; Michel, BA; Sprott, H, 2006) |
| "5 mg; n = 124) with ibuprofen (200 mg; n = 122) and placebo (n = 126) in patients with moderate-to-severe acute low back pain." | 9.10 | Relief of acute low back pain with diclofenac-K 12.5 mg tablets: a flexible dose, ibuprofen 200 mg and placebo-controlled clinical trial. ( Dreiser, RL; Gold, M; Ionescu, E; Liu, JH; Marty, M, 2003) |
| "5 mg and ibuprofen 200 mg (HC/IB) with those of combination oxycodone 5 mg and acetaminophen 325 mg (OX/AC) in the treatment of moderate or severe acute low back pain." | 9.10 | Combination hydrocodone and ibuprofen versus combination oxycodone and acetaminophen in the treatment of moderate or severe acute low back pain. ( Dornseif, BE; Doyle, RT; Morris, E; Palangio, M; Valente, TJ, 2002) |
| "To compare the efficacy of continuous low-level heat wrap therapy (40 C, 8 hours/day) with that of ibuprofen (1200 mg/day) and acetaminophen (4000 mg/day) in subjects with acute nonspecific low back pain." | 9.10 | Continuous low-level heat wrap therapy provides more efficacy than Ibuprofen and acetaminophen for acute low back pain. ( Abeln, SB; Beth Goodale, M; Erasala, GN; Hengehold, DA; Hinkle, RT; Nadler, SF; Steiner, DJ; Weingand, KW, 2002) |
| "The results confirmed that the COX-2-selective inhibitor nimesulide is an effective and well-tolerated agent for use in general practices to treat acute low back pain." | 9.09 | Treatment of acute low back pain with the COX-2-selective anti-inflammatory drug nimesulide: results of a randomized, double-blind comparative trial versus ibuprofen. ( Autio, L; Jekunen, A; Pohjolainen, T; Vuorela, H, 2000) |
| " This study seeks to compare the efficacy of intravenously administered paracetamol, dexketoprofen, and ibuprofen in patients with non-traumatic acute low back pain." | 5.51 | Comparative evaluation of the effectiveness of intravenous paracetamol, dexketoprofen and ibuprofen in acute low back pain. ( Dogan, C; Kemanci, A; Oskay, A; Ozen, M; Seyit, M; Turkcuer, I; Uluturk, M; Yilmaz, A, 2022) |
| "To assess the analgesic efficacy and safety of single-dose oral cannabidiol (CBD) as an adjunct to standard care for patients presenting to an emergency department with acute low back pain." | 5.41 | The CANBACK trial: a randomised, controlled clinical trial of oral cannabidiol for people presenting to the emergency department with acute low back pain. ( Bebee, B; Bourke, E; Ching, M; Foster, L; Pollack, K; Taylor, DM; Wong, A, 2021) |
| "Adding baclofen, metaxalone, or tizanidine to ibuprofen does not appear to improve functioning or pain any more than placebo plus ibuprofen by 1 week after an ED visit for acute low back pain." | 5.30 | A Randomized, Placebo-Controlled Trial of Ibuprofen Plus Metaxalone, Tizanidine, or Baclofen for Acute Low Back Pain. ( Friedman, BW; Gallagher, EJ; Irizarry, E; Jones, MP; Pearlman, S; Shah, PD; Solorzano, C; Wollowitz, A; Zias, E, 2019) |
| "Patients with chronic low back pain were randomly divided into 2 groups treated either with oral ibuprofen-arginine (400 mg) or with placebo." | 5.12 | Influence of ibuprofen-arginine on serum levels of nitric oxide metabolites in patients with chronic low back pain--a single-blind, placebo controlled pilot trial (ISRCTN18723747). ( Gay, RE; Gay, S; Michel, BA; Sprott, H, 2006) |
| "5 mg; n = 124) with ibuprofen (200 mg; n = 122) and placebo (n = 126) in patients with moderate-to-severe acute low back pain." | 5.10 | Relief of acute low back pain with diclofenac-K 12.5 mg tablets: a flexible dose, ibuprofen 200 mg and placebo-controlled clinical trial. ( Dreiser, RL; Gold, M; Ionescu, E; Liu, JH; Marty, M, 2003) |
| "5 mg and ibuprofen 200 mg (HC/IB) with those of combination oxycodone 5 mg and acetaminophen 325 mg (OX/AC) in the treatment of moderate or severe acute low back pain." | 5.10 | Combination hydrocodone and ibuprofen versus combination oxycodone and acetaminophen in the treatment of moderate or severe acute low back pain. ( Dornseif, BE; Doyle, RT; Morris, E; Palangio, M; Valente, TJ, 2002) |
| "To compare the efficacy of continuous low-level heat wrap therapy (40 C, 8 hours/day) with that of ibuprofen (1200 mg/day) and acetaminophen (4000 mg/day) in subjects with acute nonspecific low back pain." | 5.10 | Continuous low-level heat wrap therapy provides more efficacy than Ibuprofen and acetaminophen for acute low back pain. ( Abeln, SB; Beth Goodale, M; Erasala, GN; Hengehold, DA; Hinkle, RT; Nadler, SF; Steiner, DJ; Weingand, KW, 2002) |
| "The results confirmed that the COX-2-selective inhibitor nimesulide is an effective and well-tolerated agent for use in general practices to treat acute low back pain." | 5.09 | Treatment of acute low back pain with the COX-2-selective anti-inflammatory drug nimesulide: results of a randomized, double-blind comparative trial versus ibuprofen. ( Autio, L; Jekunen, A; Pohjolainen, T; Vuorela, H, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 9 (40.91) | 29.6817 |
| 2010's | 4 (18.18) | 24.3611 |
| 2020's | 7 (31.82) | 2.80 |
| Authors | Studies |
|---|---|
| Wertli, MM | 1 |
| Flury, JS | 1 |
| Streit, S | 1 |
| Limacher, A | 1 |
| Schuler, V | 1 |
| Ferrante, AN | 1 |
| Rimensberger, C | 1 |
| Haschke, M | 1 |
| Dogan, C | 1 |
| Yilmaz, A | 1 |
| Ozen, M | 1 |
| Seyit, M | 1 |
| Oskay, A | 1 |
| Kemanci, A | 1 |
| Uluturk, M | 1 |
| Turkcuer, I | 1 |
| Slawson, DC | 1 |
| Abdallah, NA | 1 |
| Fathy, ME | 1 |
| Tolba, MM | 1 |
| El-Brashy, AM | 1 |
| Ibrahim, FA | 1 |
| Friedman, BW | 3 |
| Irizarry, E | 3 |
| Chertoff, A | 1 |
| Feliciano, C | 2 |
| Solorzano, C | 2 |
| Zias, E | 2 |
| Gallagher, EJ | 2 |
| Bebee, B | 1 |
| Taylor, DM | 1 |
| Bourke, E | 1 |
| Pollack, K | 1 |
| Foster, L | 1 |
| Ching, M | 1 |
| Wong, A | 1 |
| Restivo, A | 1 |
| Salama, M | 1 |
| Davitt, M | 1 |
| Cortijo-Brown, A | 1 |
| Pearlman, S | 1 |
| Wollowitz, A | 1 |
| Jones, MP | 1 |
| Shah, PD | 1 |
| Enthoven, WT | 1 |
| Roelofs, PD | 1 |
| Deyo, RA | 1 |
| van Tulder, MW | 1 |
| Koes, BW | 1 |
| Sun, YZ | 1 |
| Li, DY | 1 |
| Finsterer, J | 1 |
| Brunner, S | 1 |
| Nadler, SF | 2 |
| Steiner, DJ | 2 |
| Petty, SR | 1 |
| Erasala, GN | 2 |
| Hengehold, DA | 2 |
| Weingand, KW | 2 |
| Dreiser, RL | 1 |
| Marty, M | 1 |
| Ionescu, E | 1 |
| Gold, M | 1 |
| Liu, JH | 1 |
| Ting, A | 1 |
| Freund, J | 1 |
| Vas, J | 1 |
| Perea-Milla, E | 1 |
| Mendez, C | 1 |
| Silva, LC | 1 |
| Herrera Galante, A | 1 |
| Aranda Regules, JM | 1 |
| Martinez Barquin, DM | 1 |
| Aguilar, I | 1 |
| Faus, V | 1 |
| Sprott, H | 1 |
| Gay, RE | 1 |
| Michel, BA | 1 |
| Gay, S | 1 |
| Milgrom, C | 1 |
| Finestone, A | 1 |
| Lev, B | 1 |
| Wiener, M | 1 |
| Floman, Y | 1 |
| Baum, K | 1 |
| Engels, B | 1 |
| Vögtle-Junkert, U | 1 |
| Schattenkirchner, M | 1 |
| Pohjolainen, T | 1 |
| Jekunen, A | 1 |
| Autio, L | 1 |
| Vuorela, H | 1 |
| Palangio, M | 1 |
| Morris, E | 1 |
| Doyle, RT | 1 |
| Dornseif, BE | 1 |
| Valente, TJ | 1 |
| Hinkle, RT | 1 |
| Beth Goodale, M | 1 |
| Abeln, SB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Metamizole Versus Ibuprofen and a Short Educational Intervention Versus Standard Care in Acute and Subacute Low Back Pain: A Randomized, Factorial Trial[NCT04111315] | Phase 4 | 120 participants (Anticipated) | Interventional | 2019-12-15 | Recruiting | ||
| The Randomized Double-Blind Comparison of Analgesic Efficacy Between Intravenous Forms of Ibuprofen 400 and Ibuprofen 800 mg in Acute Mechanical Low Back Pain in the Emergency Department[NCT06064175] | Phase 4 | 144 participants (Actual) | Interventional | 2022-01-01 | Completed | ||
| Ibuprofen Plus Metaxolone, Tizanidine, or Baclofen for Low Back Pain: A Randomized Trial[NCT03068897] | Phase 4 | 320 participants (Actual) | Interventional | 2017-05-03 | Completed | ||
| Addressing Opioid Use Disorder With an External Multimodal Neuromodulation Device: Clinical Evaluation of DuoTherm for Opioid-Sparing in Acute Low Back Pain[NCT04491175] | 60 participants (Anticipated) | Interventional | 2022-06-23 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"The Roland Morris Disability Questionnaire (RMDQ) is a 24 item instrument that evaluates the impact of low back pain on one's daily life. It is most sensitive for patients with mild to moderate disability due to acute, sub-acute or chronic low back pain. Each question can be answered as either a yes or no. The score ranges from 0 to 24 where a higher score reflects greater impairment and, therefore, worsening in the quality of life. The change in RMDQ is obtained by subtracting the RMDQ score at one week after discharge from the baseline score." (NCT03068897)
Timeframe: Baseline and 7 days
| Intervention | units on a scale (Mean) |
|---|---|
| Metaxalone | 10.1 |
| Tizanidine | 11.2 |
| Baclofen | 10.6 |
| Placebo | 11.1 |
Disability will be assessed with the Roland-Morris Disability Questionnaire (RMDQ) where patients are asked to tick a box if they agree with 24 statements regarding their ability to perform certain activities (dressing, housework, walking). If the don't agree with the statement (able to perform those activities) they need to leave the tick-box blank or unchecked. Every agreement (tick) counts as a point and an absolute value is formed (min: 0, max: 24). The higher the value the higher the disability level. (NCT03068897)
Timeframe: 7 days
| Intervention | units on a scale (Median) |
|---|---|
| Metaxalone | 5 |
| Tizanidine | 3 |
| Baclofen | 6 |
| Placebo | 3 |
Change is assessed by verbal numerical scale of which 0 represents no pain and 10 represents the worst pain imaginable between the baseline ED visit and the one week follow-up (baseline - 1 week ). The baseline questions will refer to the time period immediately prior to ED presentation (Before you came to the ER today, were you able to…..) (NCT03068897)
Timeframe: Baseline and 7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Metaxalone | 28 |
| Tizanidine | 25 |
| Baclofen | 26 |
| Placebo | 22 |
Patients will be asked what medications they have used for low back pain (NCT03068897)
Timeframe: 7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Metaxalone | 49 |
| Tizanidine | 48 |
| Baclofen | 49 |
| Placebo | 46 |
1 review available for ibuprofen and Low Back Pain
| Article | Year |
|---|---|
Non-steroidal anti-inflammatory drugs for chronic low back pain.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Diclofenac; Disability Evaluation; Humans; Ib | 2016 |
14 trials available for ibuprofen and Low Back Pain
| Article | Year |
|---|---|
Efficacy of metamizole versus ibuprofen and a short educational intervention versus standard care in acute and subacute low back pain: a study protocol of a randomised, multicentre, factorial trial (EMISI trial).
Topics: Analgesics, Non-Narcotic; Dipyrone; Double-Blind Method; Humans; Ibuprofen; Low Back Pain; Multicent | 2021 |
Comparative evaluation of the effectiveness of intravenous paracetamol, dexketoprofen and ibuprofen in acute low back pain.
Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double | 2022 |
Ibuprofen Plus Acetaminophen Versus Ibuprofen Alone for Acute Low Back Pain: An Emergency Department-based Randomized Study.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 2020 |
The CANBACK trial: a randomised, controlled clinical trial of oral cannabidiol for people presenting to the emergency department with acute low back pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Australia; Cannabidiol; Double-Blind Method; | 2021 |
A randomized controlled trial of ibuprofen versus ketorolac versus diclofenac for acute, nonradicular low back pain.
Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Humans; Ibupro | 2021 |
A Randomized, Placebo-Controlled Trial of Ibuprofen Plus Metaxalone, Tizanidine, or Baclofen for Acute Low Back Pain.
Topics: Acute Pain; Adult; Analgesics, Non-Narcotic; Baclofen; Clonidine; Double-Blind Method; Drug Therapy, | 2019 |
[Observation on lower back myofascitis treated with penetration needling on yang meridians of the back and electroacupuncture as compared with Western medication].
Topics: Adult; Electroacupuncture; Fasciitis; Female; Humans; Ibuprofen; Low Back Pain; Male; Meridians; Mid | 2010 |
Overnight use of continuous low-level heatwrap therapy for relief of low back pain.
Topics: Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Demography; Disability Evaluation; Femal | 2003 |
Relief of acute low back pain with diclofenac-K 12.5 mg tablets: a flexible dose, ibuprofen 200 mg and placebo-controlled clinical trial.
Topics: Acute Disease; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind | 2003 |
Influence of ibuprofen-arginine on serum levels of nitric oxide metabolites in patients with chronic low back pain--a single-blind, placebo controlled pilot trial (ISRCTN18723747).
Topics: Analgesics; Arginine; Chronic Disease; Drug Combinations; Female; Humans; Ibuprofen; Low Back Pain; | 2006 |
Overexertional lumbar and thoracic back pain among recruits: a prospective study of risk factors and treatment regimens.
Topics: Acetaminophen; Adolescent; Anthropometry; Back Pain; Body Mass Index; Cumulative Trauma Disorders; H | 1993 |
Treatment of acute low back pain with the COX-2-selective anti-inflammatory drug nimesulide: results of a randomized, double-blind comparative trial versus ibuprofen.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 In | 2000 |
Combination hydrocodone and ibuprofen versus combination oxycodone and acetaminophen in the treatment of moderate or severe acute low back pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 2002 |
Continuous low-level heat wrap therapy provides more efficacy than Ibuprofen and acetaminophen for acute low back pain.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Female; Follow-Up Studies | 2002 |
7 other studies available for ibuprofen and Low Back Pain
| Article | Year |
|---|---|
Ibuprofen, Ketorolac, and Diclofenac Are Equivalent for the Treatment of Acute, Nonradicular Low Back Pain.
Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Humans; Ibupro | 2022 |
Green Constant-wavelength Concurrent Selective Fluorescence Method for Assay of Ibuprofen and Chlorzoxazone in Presence of Chlorzoxazone Degradation Product.
Topics: Chlorzoxazone; Fluorescence; Humans; Ibuprofen; Low Back Pain; Pharmaceutical Preparations; Spectrom | 2023 |
Ibuprofen-induced unilateral optic neuritis.
Topics: Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Low Back Pain; Middle Aged; Optic Neuritis | 2012 |
[Acute back pain. Two-thirds are functional complaints].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Causality; Cross-Sectional Studies; Cyclooxygenase Inhibito | 2003 |
Nonsteroidal antiinflammatory-induced acute renal failure detected on bone scintigraphy.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Bone and Bones; Diclofenac; Humans; Ib | 2004 |
Efficacy and safety of acupuncture for the treatment of non-specific acute low back pain: a randomised controlled multicentre trial protocol [ISRCTN65814467].
Topics: Acetaminophen; Acupuncture; Acute Disease; Adult; Amitriptyline; Analgesics; Bayes Theorem; Clinical | 2006 |
[High dose ibuprofen in low back pain].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Female; Humans; Ibuprofen | 1997 |