Page last updated: 2024-10-28

ibuprofen and Liver Failure, Acute

ibuprofen has been researched along with Liver Failure, Acute in 7 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.

Research Excerpts

ExcerptRelevanceReference
" The failure is secondary to an idiosyncratic reaction to ibuprofen, an entity included in the DRESS syndrome."7.80DRESS syndrome secondary to ibuprofen as a cause of hyperacute liver failure. ( Casabona-Francés, S; Catalán, M; Colina, F; Molero, AI; Pérez-Amarilla, I; Rey-Díaz-Rubio, E; Roales-Gómez, V; Vanaclocha, F, 2014)
" The failure is secondary to an idiosyncratic reaction to ibuprofen, an entity included in the DRESS syndrome."3.80DRESS syndrome secondary to ibuprofen as a cause of hyperacute liver failure. ( Casabona-Francés, S; Catalán, M; Colina, F; Molero, AI; Pérez-Amarilla, I; Rey-Díaz-Rubio, E; Roales-Gómez, V; Vanaclocha, F, 2014)
"Ibuprofen is a worldwide used non-steroidal anti-inflammatory drug which may cause acute liver injury (ALI) requiring liver transplantation."1.51Protective role of c-Jun N-terminal kinase-2 (JNK2) in ibuprofen-induced acute liver injury. ( Andrade, RJ; Bast, A; Bechmann, LP; Cubero, FJ; Koek, GH; Lucena, MI; Nelson, LJ; Sydor, S; Trautwein, C; Woitok, MM; Zoubek, ME, 2019)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Raghu, K1
Berry, MJ1
Zoubek, ME2
Lucena, MI2
Andrade, RJ2
Stephens, C1
Woitok, MM1
Sydor, S1
Nelson, LJ1
Bechmann, LP1
Bast, A1
Koek, GH1
Trautwein, C1
Cubero, FJ1
Roales-Gómez, V1
Molero, AI1
Pérez-Amarilla, I1
Casabona-Francés, S1
Rey-Díaz-Rubio, E1
Catalán, M1
Vanaclocha, F1
Colina, F1
Hydzik, P1
Gawlikowski, T1
Groszek, B1
Javier Rodríguez-González, F1
Montero, JL1
Puente, J1
Fraga, E1
Costán, G1
Barrera, P1
Muntané, J1
De la Mata, M1
Zambrana, JL1
Yasuda, H1
Yoshiba, S1

Reviews

2 reviews available for ibuprofen and Liver Failure, Acute

ArticleYear
Systematic review: ibuprofen-induced liver injury.
    Alimentary pharmacology & therapeutics, 2020, Volume: 51, Issue:6

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Chemical and

2020
[Fulminant hepatitis].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Age

2007

Other Studies

5 other studies available for ibuprofen and Liver Failure, Acute

ArticleYear
Acute liver failure secondary to therapeutic paracetamol dosing in an extremely preterm neonate.
    BMJ case reports, 2022, May-06, Volume: 15, Issue:5

    Topics: Acetaminophen; Ductus Arteriosus, Patent; Humans; Ibuprofen; Infant; Infant, Extremely Premature; In

2022
Protective role of c-Jun N-terminal kinase-2 (JNK2) in ibuprofen-induced acute liver injury.
    The Journal of pathology, 2019, Volume: 247, Issue:1

    Topics: Animals; Cell Death; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Enzyme Activati

2019
DRESS syndrome secondary to ibuprofen as a cause of hyperacute liver failure.
    Revista espanola de enfermedades digestivas, 2014, Volume: 106, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Hypersensitivity Syndrome; Humans; Ibuprofen; Liver Fa

2014
[Drug-induced erythrodermia complicated by multiorgan failure--case report].
    Przeglad lekarski, 2011, Volume: 68, Issue:8

    Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Clarithromycin; Dermatitis, Exfoliati

2011
Orthotopic liver transplantation after subacute liver failure induced by therapeutic doses of ibuprofen.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Liver Failure, Acute; Liver Tran

2002