Page last updated: 2024-10-28

ibuprofen and Libman-Sacks Disease

ibuprofen has been researched along with Libman-Sacks Disease in 37 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Research Excerpts

ExcerptRelevanceReference
"The use of ibuprofen by patients with systemic lupus erythematosus poses a major threat of aseptic meningitis."7.67Ibuprofen-induced meningitis in an elderly patient with systemic lupus erythematosus. ( Eichenbaum, HW; Gilbert, GJ, 1989)
"A 36-year-old male with systemic lupus erythematosus developed aseptic meningitis after ingestion of ibuprofen."7.67Ibuprofen-induced meningitis in a male with systemic lupus erythematosus. ( Bacher, T; Ersgaard, H; Glud, TK; Jensen, S, 1987)
"A 33 year old female with systemic lupus erythematosus developed an aseptic meningitis with a polymorphonuclear CSF pleocytosis temporally correlated with ibuprofen."7.66Ibuprofen, meningitis, and systemic lupus erythematosus. ( Wasner, CK, 1978)
"Ibuprofen rarely causes lower gastrointestinal adverse reactions but has been implicated in systemic and local side effects in patients with lupus."5.28Ulcerative proctitis in juvenile systemic lupus erythematosus after ibuprofen treatment. ( Khoury, MI, 1989)
"A 21-year-old woman with systemic lupus erythematosus (SLE) had meningismus, conjunctivitis, lymphadenopathy, and elevation of liver function values following ibuprofen therapy."5.26Tolmetin-induced aseptic meningitis. ( Barth, WF; Ruppert, GB, 1981)
"A patient with systemic lupus erythematosus had chills, fever, and headache on four separate occasions after ibuprofen ingestion."5.26Ibuprofen-induced meningitis in systemic lupus erythematosus. ( Littman, BH; Widener, HL, 1978)
"The use of ibuprofen by patients with systemic lupus erythematosus poses a major threat of aseptic meningitis."3.67Ibuprofen-induced meningitis in an elderly patient with systemic lupus erythematosus. ( Eichenbaum, HW; Gilbert, GJ, 1989)
"A 36-year-old male with systemic lupus erythematosus developed aseptic meningitis after ingestion of ibuprofen."3.67Ibuprofen-induced meningitis in a male with systemic lupus erythematosus. ( Bacher, T; Ersgaard, H; Glud, TK; Jensen, S, 1987)
"Three young women with systemic lupus erythematosus who were given ibuprofen for arthritis voluntarily discontinued taking the drug."3.66Acute adverse reactions to ibuprofen in systemic lupus erythematosus. ( Finch, WR; Strottman, MP, 1979)
"A 33 year old female with systemic lupus erythematosus developed an aseptic meningitis with a polymorphonuclear CSF pleocytosis temporally correlated with ibuprofen."3.66Ibuprofen, meningitis, and systemic lupus erythematosus. ( Wasner, CK, 1978)
"A 14-year-old girl with systemic lupus erythematosus presented with a mixed overdose of paracetamol, ibuprofen and azathioprine (1500 mg) following a deliberate self-harm attempt."2.49Intentional overdose of azathioprine in a patient with systemic lupus erythematosus. ( Khan, AM; Mahmood, K; Martin, K; Ramanan, AV, 2013)
"Aseptic meningitis is one of the most infrequent neuropsychiatric manifestations of systemic lupus erythematosus (SLE) with multifactorial etiologies including medications such as nonsteroidal anti-inflammatory drugs, azathioprine, and trimethoprim-sulfamethoxasole, as well as viruses and malignancy."1.35Recurrent benign lymphocytic (mollaret) meningitis in systemic lupus erythematosus. ( Kennedy, S; Krumholz, A; Mikdashi, J, 2008)
"Ibuprofen rarely causes lower gastrointestinal adverse reactions but has been implicated in systemic and local side effects in patients with lupus."1.28Ulcerative proctitis in juvenile systemic lupus erythematosus after ibuprofen treatment. ( Khoury, MI, 1989)
"Serum from a patient with inactive systemic lupus erythematosus (SLE) and ibuprofen-induced transient neutropenia was used as a probe to define further the control of human polymorphonuclear leukocyte (PMN) exocytosis and superoxide (O2-) generation."1.27Independent regulation of leukotriene B4-elicited polymorphonuclear leukocyte exocytosis and superoxide generation by a serum factor. ( Mandell, BF, 1987)
"A 23-year-old woman with systemic lupus erythematosus had a severe hypersensitivity reaction to the drug ibuprofen."1.27Severe systemic hypersensitivity reaction to ibuprofen occurring after prolonged therapy. ( Mandell, BF; Raps, EC, 1987)
"2 patients with systemic lupus erythematosus and mild renal functional impairment were treated with ibuprofen, one of the phenylproprionic nonsteroidal anti-inflammatory drugs."1.26Ibuprofen-induced acute renal failure with acute tubular necrosis. ( Cohen, AH; Fong, HJ, 1982)
"A 21-year-old woman with systemic lupus erythematosus (SLE) had meningismus, conjunctivitis, lymphadenopathy, and elevation of liver function values following ibuprofen therapy."1.26Tolmetin-induced aseptic meningitis. ( Barth, WF; Ruppert, GB, 1981)
"A patient with systemic lupus erythematosus had chills, fever, and headache on four separate occasions after ibuprofen ingestion."1.26Ibuprofen-induced meningitis in systemic lupus erythematosus. ( Littman, BH; Widener, HL, 1978)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199027 (72.97)18.7374
1990's4 (10.81)18.2507
2000's3 (8.11)29.6817
2010's3 (8.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mahmood, K1
Khan, AM1
Ramanan, AV1
Martin, K1
Yinh, J1
Pilichowska, M1
Kalish, R1
Faurie, P1
Pérard, L1
Hot, A1
Desmurs-Clavel, H1
Fassier, T1
Boibieux, A1
Ninet, J1
Hidalgo Natera, A1
Cárdenas Contreras, R1
Najem Risk, N1
Canto Díez, G1
Mou, SS1
Punaro, L1
Antón, J1
Luckett, PM1
Mikdashi, J1
Kennedy, S1
Krumholz, A1
Furst, DE1
Kelley, VE2
Izui, S1
Halushka, PV1
Trèves, R1
Gastine, H1
Richard, A1
Hugon, J1
Varnoux, M1
Gay, R1
Desproges-Gotteron, R1
Karsh, J1
Kimberly, RP2
Stahl, NI1
Plotz, PH2
Decker, JL1
Zawada, ET1
Fong, HJ1
Cohen, AH1
Shoenfeld, Y2
Livni, E1
Shaklai, M1
Pinkhas, J2
Ruppert, GB2
Barth, WF2
Giansiracusa, DF1
Blumberg, S1
Kantrowitz, FG1
Nesher, G1
Osborn, TG1
Moore, TL1
Vigouroux, C1
Fitoussi, D1
Cariou, D1
Aerts, J1
Pasquier, P1
Skeith, KJ1
Wefuan, J1
Oswald, R1
Davis, P1
Widener, HL1
Littman, BH1
Finch, WR1
Strottman, MP1
Samuelson, CO1
Williams, HJ1
Sonnenblick, M1
Abraham, AS1
Bowden, RE1
Keiser, HR1
Wasner, CK1
Sack, KE1
Rosenthal, SH1
Mandell, B1
Shen, HS1
Hepburn, B1
Dubois, EL1
McGalliard, J1
Bell, AL1
Gilbert, GJ1
Eichenbaum, HW1
Khoury, MI1
Mandell, BF2
Sneve, S1
Musinski, S1
Raps, EC1
Jensen, S1
Glud, TK1
Bacher, T1
Ersgaard, H1
Patrono, C1
Ciabattoni, G1
Remuzzi, G1
Gotti, E1
Bombardieri, S1
Di Munno, O1
Tartarelli, G1
Cinotti, GA1
Simonetti, BM1
Pierucci, A1
Berliner, S1
Weinberger, A1
Sandbank, U1
Hazaz, B1
Joshua, H1
Rosen, M1

Reviews

5 reviews available for ibuprofen and Libman-Sacks Disease

ArticleYear
Intentional overdose of azathioprine in a patient with systemic lupus erythematosus.
    Scottish medical journal, 2013, Volume: 58, Issue:4

    Topics: Acetaminophen; Adolescent; Affective Disorders, Psychotic; Anti-Inflammatory Agents, Non-Steroidal;

2013
Renal consequences of nonsteroidal antiinflammatory drugs.
    Postgraduate medicine, 1982, Volume: 71, Issue:5

    Topics: Acidosis; Acute Kidney Injury; Aged; Anti-Inflammatory Agents; Bartter Syndrome; Female; Humans; Hyp

1982
Parvovirus infection mimicking systemic lupus erythematosus.
    Seminars in arthritis and rheumatism, 1995, Volume: 24, Issue:5

    Topics: Adult; Antibodies, Antinuclear; Antibodies, Viral; Child; Diagnosis, Differential; Erythema Infectio

1995
[Disclosure of systemic lupus erythematosus in a case of hepatitis caused by ibuprofen].
    La Revue de medecine interne, 1993, Volume: 14, Issue:9

    Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Ibuprofen; Lupus Erythematosus, Syste

1993
Rheumatoid arthritis: an overview.
    Texas medicine, 1976, Volume: 72, Issue:11

    Topics: Adult; Arthritis; Arthritis, Reactive; Arthritis, Rheumatoid; Aspirin; Diagnosis, Differential; Fema

1976

Trials

1 trial available for ibuprofen and Libman-Sacks Disease

ArticleYear
Comparative effects of aspirin and ibuprofen in the management of systemic lupus erythematosus.
    Arthritis and rheumatism, 1980, Volume: 23, Issue:12

    Topics: Aspirin; Clinical Trials as Topic; Humans; Ibuprofen; Lupus Erythematosus, Systemic; Placebos; Resea

1980

Other Studies

31 other studies available for ibuprofen and Libman-Sacks Disease

ArticleYear
A 27-year-old Cambodian woman with fever, lymphadenopathy, and arthritis.
    Arthritis care & research, 2010, Volume: 62, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Asian

2010
[Recurrent aseptic meningitis secondary to nonsteroidal anti-inflammatory drugs in a patient with lupus].
    La Revue de medecine interne, 2010, Volume: 31, Issue:10

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Lupus Erythematosus, Syst

2010
[Ibuprofen, aseptic meningitis, systemic lupus erythematosus].
    Medicina clinica, 2004, May-08, Volume: 122, Issue:17

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Lupus Erythematosus, Syst

2004
Severe systemic hypersensitivity reaction to ibuprofen: a presentation of systemic lupus erythematosus.
    The Journal of rheumatology, 2006, Volume: 33, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Diagnosis, Differential; Drug Hypersensitivity; Huma

2006
Recurrent benign lymphocytic (mollaret) meningitis in systemic lupus erythematosus.
    The neurologist, 2008, Volume: 14, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Autoimmune Diseases of the Nervous System; Cerebrospinal Fl

2008
Use of ibuprofen in unusual circumstances.
    The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A

    Topics: Arthritis, Rheumatoid; Aspirin; Bartter Syndrome; Cyclooxygenase Inhibitors; Digoxin; Drug Hypersens

1984
Effect of ibuprofen, a fatty acid cyclooxygenase inhibitor, on murine lupus.
    Clinical immunology and immunopathology, 1982, Volume: 25, Issue:2

    Topics: Alprostadil; Animals; Antibodies, Antinuclear; Antigen-Antibody Complex; Cyclooxygenase Inhibitors;

1982
[Aseptic meningitis and acute renal failure induced by ibuprofen during the treatment of systemic lupus erythematosus].
    Revue du rhumatisme et des maladies osteo-articulaires, 1983, Volume: 50, Issue:1

    Topics: Acute Kidney Injury; Female; Humans; Ibuprofen; Lupus Erythematosus, Systemic; Meningitis; Meningiti

1983
Ibuprofen-induced acute renal failure with acute tubular necrosis.
    American journal of nephrology, 1982, Volume: 2, Issue:1

    Topics: Acute Kidney Injury; Adult; Biopsy; Female; Humans; Ibuprofen; Kidney Glomerulus; Kidney Tubular Nec

1982
Sensitization to ibuprofen in systemic lupus erythematosus.
    JAMA, 1980, Aug-08, Volume: 244, Issue:6

    Topics: Drug Hypersensitivity; Female; Humans; Ibuprofen; Immunization; Lupus Erythematosus, Systemic

1980
Tolmetin-induced aseptic meningitis.
    JAMA, 1981, Jan-02, Volume: 245, Issue:1

    Topics: Adult; Female; Fever; Humans; Ibuprofen; Knee; Lupus Erythematosus, Systemic; Meningitis; Meningitis

1981
Aseptic meningitis associated with ibuprofen.
    Archives of internal medicine, 1980, Volume: 140, Issue:11

    Topics: Adult; Female; Humans; Ibuprofen; Lupus Erythematosus, Systemic; Meningitis; Meningitis, Aseptic

1980
Ibuprofen hypersensitivity in systemic lupus erythematosus.
    Southern medical journal, 1981, Volume: 74, Issue:2

    Topics: Adult; Drug Hypersensitivity; Female; Humans; Ibuprofen; Lupus Erythematosus, Systemic

1981
Serum cytidine deaminase as a measure of disease activity in rheumatoid arthritis and systemic lupus erythematosus.
    The Journal of rheumatology, 1993, Volume: 20, Issue:8

    Topics: Adult; Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Cytidine Deaminase; Female; H

1993
Ibuprofen-induced meningitis in systemic lupus erythematosus.
    JAMA, 1978, Mar-13, Volume: 239, Issue:11

    Topics: Adult; Antibodies, Antinuclear; Arthritis; Female; Humans; Ibuprofen; Lupus Erythematosus, Systemic;

1978
Acute adverse reactions to ibuprofen in systemic lupus erythematosus.
    JAMA, 1979, Jun-15, Volume: 241, Issue:24

    Topics: Acute Disease; Adult; Arthritis; Drug Hypersensitivity; Female; Fever; Headache; Humans; Hypotension

1979
Ibuprofen-associated aseptic meningitis in systemic lupus erythematosus.
    The Western journal of medicine, 1979, Volume: 131, Issue:1

    Topics: Adult; Female; Humans; Ibuprofen; Lupus Erythematosus, Systemic; Meningitis; Meningitis, Aseptic

1979
Ibuprofen hypersensitivity in systemic lupus erythematosus.
    British medical journal, 1978, Mar-11, Volume: 1, Issue:6113

    Topics: Adolescent; Drug Hypersensitivity; Female; Humans; Ibuprofen; Lupus Erythematosus, Systemic; Middle

1978
Reduction of renal function by newer nonsteroidal anti-inflammatory drugs.
    The American journal of medicine, 1978, Volume: 64, Issue:5

    Topics: Adult; Anti-Inflammatory Agents; Depression, Chemical; Female; Fenoprofen; Humans; Ibuprofen; Kidney

1978
Ibuprofen, meningitis, and systemic lupus erythematosus.
    The Journal of rheumatology, 1978,Summer, Volume: 5, Issue:2

    Topics: Adult; Female; Humans; Ibuprofen; Lupus Erythematosus, Systemic; Meningitis

1978
Letter: Fever from ibuprofen in a patient with lupus erythematosus.
    Annals of internal medicine, 1976, Volume: 85, Issue:2

    Topics: Adult; Female; Fever; Humans; Ibuprofen; Lupus Erythematosus, Systemic; Phenylpropionates

1976
Letter: Ibuprofen for systemic lupus erythematosus.
    The New England journal of medicine, 1975, Oct-09, Volume: 293, Issue:15

    Topics: Adult; Aged; Female; Humans; Ibuprofen; Lupus Erythematosus, Systemic; Male; Middle Aged; Phenylprop

1975
Acquired Brown's syndrome in systemic lupus erythematosus: another ocular manifestation.
    Clinical rheumatology, 1990, Volume: 9, Issue:3

    Topics: Adult; Diclofenac; Diplopia; Fever; Humans; Hydroxychloroquine; Ibuprofen; Lupus Erythematosus, Syst

1990
Ibuprofen-induced meningitis in an elderly patient with systemic lupus erythematosus.
    Southern medical journal, 1989, Volume: 82, Issue:4

    Topics: Aged; Cerebrospinal Fluid Proteins; Female; Humans; Ibuprofen; Lupus Erythematosus, Systemic; Mening

1989
Ulcerative proctitis in juvenile systemic lupus erythematosus after ibuprofen treatment.
    The Journal of rheumatology, 1989, Volume: 16, Issue:2

    Topics: Adolescent; Female; Humans; Ibuprofen; Lupus Erythematosus, Systemic; Proctitis; Ulcer

1989
Independent regulation of leukotriene B4-elicited polymorphonuclear leukocyte exocytosis and superoxide generation by a serum factor.
    Journal of leukocyte biology, 1987, Volume: 41, Issue:4

    Topics: Exocytosis; Glucuronidase; Humans; Ibuprofen; Leukopenia; Leukotriene B4; Lupus Erythematosus, Syste

1987
Increased renal thromboxane production in murine lupus nephritis.
    The Journal of clinical investigation, 1986, Volume: 77, Issue:1

    Topics: Animals; Dinoprostone; Female; Glomerulonephritis; Ibuprofen; Kidney; Kidney Glomerulus; Lupus Eryth

1986
Severe systemic hypersensitivity reaction to ibuprofen occurring after prolonged therapy.
    The American journal of medicine, 1987, Volume: 82, Issue:4

    Topics: Adult; Diagnosis, Differential; Drug Hypersensitivity; Female; Humans; Ibuprofen; Lupus Erythematosu

1987
Ibuprofen-induced meningitis in a male with systemic lupus erythematosus.
    Acta medica Scandinavica, 1987, Volume: 221, Issue:5

    Topics: Adult; Humans; Ibuprofen; Lupus Erythematosus, Systemic; Male; Meningitis; Meningitis, Aseptic

1987
Functional significance of renal prostacyclin and thromboxane A2 production in patients with systemic lupus erythematosus.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Platelets; Chronic Disease; Dinoprost; Dinoprostone; Epoprostenol; Fe

1985
Ibuprofen may induce meningitis in (NZB X NZW)F1 mice.
    Arthritis and rheumatism, 1985, Volume: 28, Issue:1

    Topics: Animals; Brain; Disease Models, Animal; Female; Ibuprofen; Lupus Erythematosus, Systemic; Meningitis

1985