Page last updated: 2024-10-28

ibuprofen and Leg Ulcer

ibuprofen has been researched along with Leg Ulcer in 3 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Leg Ulcer: Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.

Research Excerpts

ExcerptRelevanceReference
"The aim of the study was to evaluate a novel foam dressing with continuous low-level release of ibuprofen (Biatain-Ibu foam dressing, Coloplast A/S, Humlebaek, Denmark) in persons with leg ulcers compared to local best practice."9.12A pilot (real-life) randomised clinical evaluation of a pain-relieving foam dressing: (ibuprofen-foam versus local best practice). ( Coutts, P; Fierheller, M; Sibbald, RG; Woo, K, 2007)
"The aim of the study was to evaluate a novel foam dressing with continuous low-level release of ibuprofen (Biatain-Ibu foam dressing, Coloplast A/S, Humlebaek, Denmark) in persons with leg ulcers compared to local best practice."5.12A pilot (real-life) randomised clinical evaluation of a pain-relieving foam dressing: (ibuprofen-foam versus local best practice). ( Coutts, P; Fierheller, M; Sibbald, RG; Woo, K, 2007)
"Two trials (470 participants with venous leg ulcers) evaluated ibuprofen slow-release foam dressings for persistent venous leg ulcer pain."4.88Topical agents or dressings for pain in venous leg ulcers. ( Briggs, M; Martyn-St James, M; Nelson, EA, 2012)
"There is no evidence that ibuprofen dressings offer pain relief, as measured at the first evening of use, to people with painful venous leg ulcers compared with foam dressings or best practice."4.86Topical agents or dressings for pain in venous leg ulcers. ( Briggs, M; Nelson, EA, 2010)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Briggs, M2
Nelson, EA2
Martyn-St James, M1
Sibbald, RG1
Coutts, P1
Fierheller, M1
Woo, K1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double-blind Randomized Clinical Trial to Evaluate the Reduction of Pain in the Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo, in the Outpatients Area.[NCT03676556]Phase 346 participants (Anticipated)Interventional2021-06-16Recruiting
Randomised, Double-blind Clinical Trial to Evaluate the Reduction of Pain in the Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo[NCT02584335]Phase 47 participants (Actual)Interventional2015-07-31Terminated (stopped due to Difficulties with the recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for ibuprofen and Leg Ulcer

ArticleYear
Topical agents or dressings for pain in venous leg ulcers.
    The Cochrane database of systematic reviews, 2010, Apr-14, Issue:4

    Topics: Administration, Topical; Analgesics, Non-Narcotic; Anesthetics, Local; Bandages; Debridement; Humans

2010
Topical agents or dressings for pain in venous leg ulcers.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Administration, Topical; Analgesics; Anesthetics, Local; Bandages; Debridement; Humans; Ibuprofen; L

2012
Topical agents or dressings for pain in venous leg ulcers.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Administration, Topical; Analgesics; Anesthetics, Local; Bandages; Debridement; Humans; Ibuprofen; L

2012
Topical agents or dressings for pain in venous leg ulcers.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Administration, Topical; Analgesics; Anesthetics, Local; Bandages; Debridement; Humans; Ibuprofen; L

2012
Topical agents or dressings for pain in venous leg ulcers.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Administration, Topical; Analgesics; Anesthetics, Local; Bandages; Debridement; Humans; Ibuprofen; L

2012

Trials

1 trial available for ibuprofen and Leg Ulcer

ArticleYear
A pilot (real-life) randomised clinical evaluation of a pain-relieving foam dressing: (ibuprofen-foam versus local best practice).
    International wound journal, 2007, Volume: 4 Suppl 1

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Bandages; Chronic

2007