Page last updated: 2024-10-28

ibuprofen and Learning Disabilities

ibuprofen has been researched along with Learning Disabilities in 7 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Learning Disabilities: Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.

Research Excerpts

ExcerptRelevanceReference
"In this study we examined the protective effects of icariin, a flavonol isolated from Herba epimedii, on learning and memory in a rat model with brain inflammation induced by lipopolysaccharide (LPS)."3.76Protective effects of icariin on brain dysfunction induced by lipopolysaccharide in rats. ( Gong, Q; Guo, J; Li, F; Lu, Y; Shi, J; Wu, Q, 2010)
"Ibuprofen treatment significantly reduced microglia area in cortex and hippocampus but not beta-amyloid burden."1.35CHF5074, a novel gamma-secretase modulator, attenuates brain beta-amyloid pathology and learning deficit in a mouse model of Alzheimer's disease. ( Cenacchi, V; Facchinetti, F; Hutter-Paier, B; Imbimbo, BP; Lanzillotta, A; Pizzi, M; Villetti, G; Volta, R; Windisch, M, 2009)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hashmi, AN1
Yaqinuddin, A1
Ahmed, T1
Meunier, J1
Borjini, N1
Gillis, C1
Villard, V1
Maurice, T1
Raoof, R2
Esmaeili-Mahani, S2
Abbasnejad, M2
Raoof, M2
Sheibani, V1
Kooshki, R1
Amirkhosravi, L2
Rafie, F2
Nourzadeh, M1
Hajializadeh, Z1
Haghani, J1
Imbimbo, BP1
Hutter-Paier, B1
Villetti, G1
Facchinetti, F1
Cenacchi, V1
Volta, R1
Lanzillotta, A1
Pizzi, M1
Windisch, M1
Guo, J1
Li, F1
Wu, Q1
Gong, Q1
Lu, Y1
Shi, J1
Shaw, KN1
Commins, S1
O'Mara, SM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Placebo-Controlled, Ascending Single-Dose Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of CHF 5074 in Healthy Young Male Subjects[NCT00954252]Phase 184 participants (Actual)Interventional2009-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

7 other studies available for ibuprofen and Learning Disabilities

ArticleYear
Pharmacological effects of Ibuprofen on learning and memory, muscarinic receptors gene expression and APP isoforms level in pre-frontal cortex of AlCl₃-induced toxicity mouse model.
    The International journal of neuroscience, 2015, Volume: 125, Issue:4

    Topics: Aluminum Chloride; Aluminum Compounds; Amyloid beta-Protein Precursor; Analysis of Variance; Animals

2015
Brain toxicity and inflammation induced in vivo in mice by the amyloid-β forty-two inducer aftin-4, a roscovitine derivative.
    Journal of Alzheimer's disease : JAD, 2015, Volume: 44, Issue:2

    Topics: Adenine; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Age

2015
Changes in hippocampal orexin 1 receptor expression involved in tooth pain-induced learning and memory impairment in rats.
    Neuropeptides, 2015, Volume: 50

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoxazoles; Capsaicin; Dental Pulp; Hippocampus;

2015
Noxious Stimulation of the Rat Tooth Pulp May Impair Learning and Memory Through the Induction of Hippocampal Apoptosis.
    Journal of oral & facial pain and headache, 2015,Fall, Volume: 29, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; bcl-2-Associated X Protein; Behavior, A

2015
CHF5074, a novel gamma-secretase modulator, attenuates brain beta-amyloid pathology and learning deficit in a mouse model of Alzheimer's disease.
    British journal of pharmacology, 2009, Volume: 156, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein

2009
Protective effects of icariin on brain dysfunction induced by lipopolysaccharide in rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Encephalitis; Epimedium; Flavonoids; Hippocampu

2010
Cyclooxygenase inhibition attenuates endotoxin-induced spatial learning deficits, but not an endotoxin-induced blockade of long-term potentiation.
    Brain research, 2005, Mar-21, Volume: 1038, Issue:2

    Topics: Brain-Derived Neurotrophic Factor; Corticosterone; Cyclooxygenase Inhibitors; Electrophysiology; End

2005