Page last updated: 2024-10-28

ibuprofen and Lactic Acidosis

ibuprofen has been researched along with Lactic Acidosis in 5 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Research Excerpts

ExcerptRelevanceReference
"In the ibuprofen group, but not the placebo group, there were significant declines in urinary levels of prostacyclin and thromboxane, temperature, heart rate, oxygen consumption, and lactic acidosis."9.08The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group. ( Bernard, GR; Christman, BW; Dupont, WD; Fulkerson, WJ; Higgins, SB; Russell, JA; Schein, R; Steinberg, KP; Summer, WR; Swindell, BB; Wheeler, AP; Wright, PE, 1997)
"Metformin is an antihyperglycemic agent commonly used in diabetic patients."5.37The nephrologist's role in metformin-induced lactic acidosis. ( Basterrechea, MA; de Arriba, G; Gómez-Navarro, L; Hernández-Sevillano, B; Pérez del Valle, KM; Rodríguez-Palomares, JR; Sánchez-Heras, M; Tallón, S; Torres-Guinea, M, 2011)
"In the ibuprofen group, but not the placebo group, there were significant declines in urinary levels of prostacyclin and thromboxane, temperature, heart rate, oxygen consumption, and lactic acidosis."5.08The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group. ( Bernard, GR; Christman, BW; Dupont, WD; Fulkerson, WJ; Higgins, SB; Russell, JA; Schein, R; Steinberg, KP; Summer, WR; Swindell, BB; Wheeler, AP; Wright, PE, 1997)
" Hemodialysis appears to be a beneficial therapeutic option in cases of massive acetaminophen ingestion with coma and lactic acidosis."3.83Massive acetaminophen overdose: effect of hemodialysis on acetaminophen and acetylcysteine kinetics. ( Ghannoum, M; Gosselin, S; Grunbaum, AM; Kazim, S; Villeneuve, E, 2016)
"Metformin is an antihyperglycemic agent commonly used in diabetic patients."1.37The nephrologist's role in metformin-induced lactic acidosis. ( Basterrechea, MA; de Arriba, G; Gómez-Navarro, L; Hernández-Sevillano, B; Pérez del Valle, KM; Rodríguez-Palomares, JR; Sánchez-Heras, M; Tallón, S; Torres-Guinea, M, 2011)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Pollack, BE2
Barbaro, RP2
Selewski, DT2
Carlton, EF2
Ghannoum, M1
Kazim, S1
Grunbaum, AM1
Villeneuve, E1
Gosselin, S1
Gómez-Navarro, L1
de Arriba, G1
Sánchez-Heras, M1
Pérez del Valle, KM1
Hernández-Sevillano, B1
Basterrechea, MA1
Tallón, S1
Torres-Guinea, M1
Rodríguez-Palomares, JR1
Bernard, GR1
Wheeler, AP1
Russell, JA1
Schein, R1
Summer, WR1
Steinberg, KP1
Fulkerson, WJ1
Wright, PE1
Christman, BW1
Dupont, WD1
Higgins, SB1
Swindell, BB1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00000574]Phase 30 participants Interventional1990-09-30Completed
A Phase II Double Blind Randomized Controlled Trial of High Dose Vitamin B12 in Septic Shock[NCT03783091]Phase 220 participants (Anticipated)Interventional2019-08-05Recruiting
Control of Fever in Septic Patients[NCT04227652]140 participants (Actual)Interventional2013-09-03Completed
Comparison of the Efficacy of Paracetamol and Ibuprofen in the Management of Fever in Sepsis Patients: A Randomized Double-Blind Controlled Study[NCT06061575]Phase 484 participants (Anticipated)Interventional2023-10-31Not yet recruiting
Phase 2 Single Center, Randomized, Placebo-controlled, Double-blind, Parallel Group Study to Evaluate Efficacy of Para-Tyrosine Supplementation on the Survival and Clinical Outcome in Patients With Sepsis[NCT03278730]Phase 2296 participants (Anticipated)Interventional2025-02-28Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for ibuprofen and Lactic Acidosis

ArticleYear
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
    The New England journal of medicine, 1997, Mar-27, Volume: 336, Issue:13

    Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen;

1997

Other Studies

4 other studies available for ibuprofen and Lactic Acidosis

ArticleYear
Lactic acidosis and multisystem organ failure following ibuprofen overdose requiring haemodialysis.
    BMJ case reports, 2022, Feb-07, Volume: 15, Issue:2

    Topics: Acidosis, Lactic; Adolescent; Child; Continuous Renal Replacement Therapy; Drug Overdose; Humans; Ib

2022
Lactic acidosis and multisystem organ failure following ibuprofen overdose requiring haemodialysis.
    Drug and therapeutics bulletin, 2023, Volume: 61, Issue:7

    Topics: Acidosis, Lactic; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Humans; Hypoglycem

2023
Massive acetaminophen overdose: effect of hemodialysis on acetaminophen and acetylcysteine kinetics.
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Acidosis, Lactic; Adolescent; Coma; Drug Overdose; Emergency Service,

2016
The nephrologist's role in metformin-induced lactic acidosis.
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2011, Volume: 31, Issue:5

    Topics: Acidosis, Lactic; Acute Kidney Injury; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibi

2011