Page last updated: 2024-10-28

ibuprofen and Intestinal Diseases

ibuprofen has been researched along with Intestinal Diseases in 9 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Intestinal Diseases: Pathological processes in any segment of the INTESTINE from DUODENUM to RECTUM.

Research Excerpts

ExcerptRelevanceReference
"Ibuprofen caused mild ulceration of the small intestine in 50% of rats."3.70The effects of high-dose ibuprofen and pancreatic enzymes on the intestine of the rat. ( Beno, DW; Dy, SA; Jiyamapa, VA; Kimura, RE; Lloyd-Still, JD; Uhing, MR, 1999)
"Ursodiol, the drug of choice for the treatment of cystic fibrosis liver disease, may offer a safe method of using high-dose IBU in these patients by ameliorating the enteropathy."1.31Ursodeoxycholic acid ameliorates ibuprofen-induced enteropathy in the rat. ( Beno, DW; Jiyamapa-Serna, VA; Kimura, RE; Lloyd-Still, JD; Uhing, MR, 2001)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's3 (33.33)18.2507
2000's2 (22.22)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Herz, H1
Song, Y1
Ye, Y1
Tian, L1
Linden, B1
Abu El Haija, M1
Chu, Y1
Grobe, JL1
Lengeling, RW1
Mokadem, M1
Lu, Z1
Lu, Y1
Wang, X1
Wang, F1
Zhang, Y1
Lake, H1
Goldstein, JL1
Eisen, GM1
Lewis, B1
Gralnek, IM1
Aisenberg, J1
Bhadra, P1
Berger, MF1
Kimura, RE2
Dy, SA1
Uhing, MR2
Beno, DW2
Jiyamapa, VA1
Lloyd-Still, JD2
Jiyamapa-Serna, VA1
Melarange, R1
Moore, G1
Blower, PR1
Coates, ME1
Ward, FW1
Ronaasen, V1
Wang, YQ1
Wei, JQ1
Dai, DZ1
Hidaka, T1
Hosoe, K1
Yamashita, T1
Watanabe, K1
Hiramatsu, Y1
Fujimura, H1

Trials

1 trial available for ibuprofen and Intestinal Diseases

ArticleYear
Small bowel mucosal injury is reduced in healthy subjects treated with celecoxib compared with ibuprofen plus omeprazole, as assessed by video capsule endoscopy.
    Alimentary pharmacology & therapeutics, 2007, May-15, Volume: 25, Issue:10

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Celecoxib; Drug

2007

Other Studies

8 other studies available for ibuprofen and Intestinal Diseases

ArticleYear
NSAID-Induced Enteropathy Affects Regulation of Hepatic Glucose Production by Decreasing GLP-1 Secretion.
    Nutrients, 2021, Dec-28, Volume: 14, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diet, High-Fat; Disease Models, Animal; Glucagon-L

2021
Activation of intestinal GR-FXR and PPARĪ±-UGT signaling exacerbates ibuprofen-induced enteropathy in mice.
    Archives of toxicology, 2018, Volume: 92, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile Acids and Salts; Cystathionine gamma-Lyase; D

2018
Ibuprofen belly: A case of small bowel stricture due to non-steroidal anti-inflammatory drug abuse in the setting of codeine dependence.
    The Australian and New Zealand journal of psychiatry, 2013, Volume: 47, Issue:12

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Constriction, Pathologic; Humans; Ibuprofen

2013
The effects of high-dose ibuprofen and pancreatic enzymes on the intestine of the rat.
    Journal of pediatric gastroenterology and nutrition, 1999, Volume: 29, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Ibuprofen; Intestinal Diseases; Intestine

1999
Ursodeoxycholic acid ameliorates ibuprofen-induced enteropathy in the rat.
    Journal of pediatric gastroenterology and nutrition, 2001, Volume: 32, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catheterization; Cholagogues and Choleretics; Cyst

2001
A comparison of indomethacin with ibuprofen on gastrointestinal mucosal integrity in conventional and germ-free rats.
    Alimentary pharmacology & therapeutics, 1992, Volume: 6, Issue:1

    Topics: Animals; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Germ-Free Life; Ibuprofen; Indomethaci

1992
[Preventive effect of changzhankang in experimental intestinal adhesions in rats].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1991, Volume: 11, Issue:8

    Topics: Animals; Drugs, Chinese Herbal; Female; Ibuprofen; Intestinal Diseases; Rats; Rats, Inbred Strains;

1991
Analgesic and anti-inflammatory activities in rats of alpha-(3,5-di-t-butyl-4-hydroxybenzylidene)-gamma-butyrolactone (KME-4), and its intestinal damage.
    The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:10

    Topics: 4-Butyrolactone; Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis,

1986