ibuprofen has been researched along with Injuries, Spinal Cord in 12 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pretreatment with p-chlorophenylalanine, indomethacin, ibuprofen, and nimodipine attenuated the SCEP changes immediately after trauma and resulted in a marked reduction in edema formation, BSCB permeability, and blood flow changes at 5 h." | 3.71 | Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials: a pharmacological and morphological study in the rat. ( Sharma, HS; Winkler, T, 2002) |
| "Treatment of mice with complete spinal cord transection demonstrates long-distance raphespinal axon regeneration in the presence of ibuprofen." | 1.35 | Ibuprofen enhances recovery from spinal cord injury by limiting tissue loss and stimulating axonal growth. ( Baughman, K; Budel, S; Gould, G; Song, KH; Strittmatter, SM; Wang, X, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, A | 1 |
| Ryder, S | 1 |
| Sevigny, M | 1 |
| Monden, KR | 1 |
| Battaglino, RA | 1 |
| Nguyen, N | 1 |
| Goldstein, R | 1 |
| Morse, LR | 1 |
| Guha, L | 1 |
| Kumar, H | 1 |
| Bighinati, A | 1 |
| Focarete, ML | 1 |
| Gualandi, C | 1 |
| Pannella, M | 1 |
| Giuliani, A | 1 |
| Beggiato, S | 1 |
| Ferraro, L | 1 |
| Lorenzini, L | 1 |
| Giardino, L | 1 |
| Calzà, L | 1 |
| Pires, LR | 1 |
| Lopes, CDF | 1 |
| Salvador, D | 1 |
| Rocha, DN | 1 |
| Pêgo, AP | 1 |
| Sharp, KG | 1 |
| Yee, KM | 1 |
| Stiles, TL | 1 |
| Aguilar, RM | 1 |
| Steward, O | 1 |
| Redondo-Castro, E | 1 |
| Navarro, X | 1 |
| Streijger, F | 1 |
| Lee, JH | 1 |
| Duncan, GJ | 1 |
| Ng, MT | 1 |
| Assinck, P | 1 |
| Bhatnagar, T | 1 |
| Plunet, WT | 1 |
| Tetzlaff, W | 1 |
| Kwon, BK | 1 |
| Lynch, M | 1 |
| Duffell, L | 1 |
| Sandhu, M | 1 |
| Srivatsan, S | 1 |
| Deatsch, K | 1 |
| Kessler, A | 1 |
| Mitchell, GS | 1 |
| Jayaraman, A | 1 |
| Rymer, WZ | 1 |
| Kopp, MA | 1 |
| Liebscher, T | 1 |
| Watzlawick, R | 1 |
| Martus, P | 1 |
| Laufer, S | 1 |
| Blex, C | 1 |
| Schindler, R | 1 |
| Jungehulsing, GJ | 1 |
| Knüppel, S | 1 |
| Kreutzträger, M | 1 |
| Ekkernkamp, A | 1 |
| Dirnagl, U | 1 |
| Strittmatter, SM | 2 |
| Niedeggen, A | 1 |
| Schwab, JM | 1 |
| Wang, X | 1 |
| Budel, S | 1 |
| Baughman, K | 1 |
| Gould, G | 1 |
| Song, KH | 1 |
| Xing, B | 1 |
| Li, H | 1 |
| Wang, H | 1 |
| Mukhopadhyay, D | 1 |
| Fisher, D | 1 |
| Gilpin, CJ | 1 |
| Li, S | 1 |
| Sharma, HS | 1 |
| Winkler, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Rho-Inhibitor Ibuprofen for the Treatment of Acute Spinal Cord Injury: Investigation of Safety, Feasibility and Pharmacokinetics[NCT02096913] | Phase 1 | 12 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ibuprofen and Injuries, Spinal Cord
| Article | Year |
|---|---|
Drug Repurposing for Spinal Cord Injury: Progress Towards Therapeutic Intervention for Primary Factors and Secondary Complications.
Topics: Aspirin; Drug Repositioning; Humans; Ibuprofen; Inflammation; Spinal Cord Injuries | 2023 |
2 trials available for ibuprofen and Injuries, Spinal Cord
| Article | Year |
|---|---|
Effect of acute intermittent hypoxia on motor function in individuals with chronic spinal cord injury following ibuprofen pretreatment: A pilot study.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Isometric Contraction; Male; Middl | 2017 |
SCISSOR-Spinal Cord Injury Study on Small molecule-derived Rho inhibition: a clinical study protocol.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Gastrointestinal Hemorrhag | 2016 |
9 other studies available for ibuprofen and Injuries, Spinal Cord
| Article | Year |
|---|---|
Association between weekly exercise minutes and resting IL-6 in adults with chronic spinal cord injury: findings from the fracture risk after spinal cord injury exercise study.
Topics: Adult; Biomarkers; C-Reactive Protein; Cross-Sectional Studies; Exercise; Female; Humans; Ibuprofen; | 2022 |
Improved Functional Recovery in Rat Spinal Cord Injury Induced by a Drug Combination Administered with an Implantable Polymeric Delivery System.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Drug Delivery Systems; Female; | 2020 |
Ibuprofen-loaded fibrous patches-taming inhibition at the spinal cord injury site.
Topics: Animals; Cells, Cultured; Dioxanes; Drug Carriers; Drug Delivery Systems; Ibuprofen; Mice; Microtech | 2017 |
A re-assessment of the effects of treatment with a non-steroidal anti-inflammatory (ibuprofen) on promoting axon regeneration via RhoA inhibition after spinal cord injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Axons; Female; Ibuprofen; Motor Activity; Nerve Re | 2013 |
Chronic ibuprofen administration reduces neuropathic pain but does not exert neuroprotection after spinal cord injury in adult rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium-Binding Proteins; Evoked Potentials, Motor | 2014 |
Combinatorial treatment of acute spinal cord injury with ghrelin, ibuprofen, C16, and ketogenic diet does not result in improved histologic or functional outcome.
Topics: Animals; Benzenesulfonates; Biomechanical Phenomena; Complement C6; Diet, Ketogenic; Disease Models, | 2014 |
Ibuprofen enhances recovery from spinal cord injury by limiting tissue loss and stimulating axonal growth.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Axotomy; Chick Embryo; Disease Models, Animal; Eff | 2009 |
RhoA-inhibiting NSAIDs promote axonal myelination after spinal cord injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Axons; Cells, Cultured; Female; Ibuprofen; Indomet | 2011 |
Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials: a pharmacological and morphological study in the rat.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Anti-I | 2002 |