Page last updated: 2024-10-28

ibuprofen and Infant, Newborn, Diseases

ibuprofen has been researched along with Infant, Newborn, Diseases in 6 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Infant, Newborn, Diseases: Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.

Research Excerpts

ExcerptRelevanceReference
"Expectant management for PDA in extremely premature infants was noninferior to early ibuprofen treatment with respect to necrotizing enterocolitis, bronchopulmonary dysplasia, or death at 36 weeks' postmenstrual age."5.69Expectant Management or Early Ibuprofen for Patent Ductus Arteriosus. ( Avino, D; de Baat, T; De Bisschop, B; de Boode, WP; de Vries, WB; Derriks, F; Dijk, PH; Dijkman, KP; Donders, R; Henriksen, TB; Hocq, C; Hundscheid, T; Kooi, EMW; Kroon, AA; Kyng, KJ; Meeus, M; Mulder, AL; Mulder-de Tollenaer, SM; Nuytemans, DHGM; Onland, W; van Kaam, AH; Van Overmeire, B; Vijlbrief, DC; Villamor, E; Visser, R; Zecic, A, 2023)
"Persistent patent ductus arteriosus (PDA) is a common pathology in the preterm whose traditional treatment has been indomethacin."2.44[Ibuprofen versus indomethacin in the preterm persistent patent ductus arteriosus therapy: review and meta-analysis]. ( Fernández Gilino, C; Gimeno Navarro, A; Gutiérrez Laso, A; Izquierdo Macián, I; Modesto Alapont, V; Morcillo Sopena, F, 2007)
"Ibuprofen was more effective than indomethacin in the high mortality model (lethal dose for 90% survival of group)."1.26Improved survival in the suckling rat model of group B streptococcal sepsis after treatment with nonsteroidal anti-inflammatory drugs. ( Fletcher, JR; Miller, MK; Short, BL, 1982)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Bin-Nun, A1
Abu-Omar, R1
Shchors, I1
Mimouni, F1
Hammerman, C1
Hundscheid, T2
Onland, W2
Kooi, EMW2
Vijlbrief, DC2
de Vries, WB2
Dijkman, KP2
van Kaam, AH2
Villamor, E2
Kroon, AA2
Visser, R2
Mulder-de Tollenaer, SM2
De Bisschop, B2
Dijk, PH2
Avino, D2
Hocq, C2
Zecic, A2
Meeus, M2
de Baat, T2
Derriks, F2
Henriksen, TB2
Kyng, KJ2
Donders, R2
Nuytemans, DHGM2
Van Overmeire, B2
Mulder, AL2
de Boode, WP2
Yen, TA1
Wang, CC1
Johnston, PG1
Gillam-Krakauer, M1
Fuller, MP1
Reese, J1
Gimeno Navarro, A1
Modesto Alapont, V1
Morcillo Sopena, F1
Fernández Gilino, C1
Izquierdo Macián, I1
Gutiérrez Laso, A1
Short, BL1
Miller, MK1
Fletcher, JR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multi-center, Randomized Non-inferiority Trial of Early Treatment Versus Expectative Management of Patent Ductus Arteriosus in Preterm Infants (BeNeDuctus Trial - Belgium Netherlands Ductus Trial)[NCT02884219]273 participants (Actual)Interventional2016-12-23Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for ibuprofen and Infant, Newborn, Diseases

ArticleYear
Evidence-based use of indomethacin and ibuprofen in the neonatal intensive care unit.
    Clinics in perinatology, 2012, Volume: 39, Issue:1

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Evidence-Based Medicine; Humans; Ibuprofen; In

2012
[Ibuprofen versus indomethacin in the preterm persistent patent ductus arteriosus therapy: review and meta-analysis].
    Anales de pediatria (Barcelona, Spain : 2003), 2007, Volume: 67, Issue:4

    Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Echoca

2007

Trials

1 trial available for ibuprofen and Infant, Newborn, Diseases

ArticleYear
Expectant Management or Early Ibuprofen for Patent Ductus Arteriosus.
    The New England journal of medicine, 2023, Mar-16, Volume: 388, Issue:11

    Topics: Bronchopulmonary Dysplasia; Ductus Arteriosus, Patent; Echocardiography; Enterocolitis, Necrotizing;

2023
Expectant Management or Early Ibuprofen for Patent Ductus Arteriosus.
    The New England journal of medicine, 2023, Mar-16, Volume: 388, Issue:11

    Topics: Bronchopulmonary Dysplasia; Ductus Arteriosus, Patent; Echocardiography; Enterocolitis, Necrotizing;

2023
Expectant Management or Early Ibuprofen for Patent Ductus Arteriosus.
    The New England journal of medicine, 2023, Mar-16, Volume: 388, Issue:11

    Topics: Bronchopulmonary Dysplasia; Ductus Arteriosus, Patent; Echocardiography; Enterocolitis, Necrotizing;

2023
Expectant Management or Early Ibuprofen for Patent Ductus Arteriosus.
    The New England journal of medicine, 2023, Mar-16, Volume: 388, Issue:11

    Topics: Bronchopulmonary Dysplasia; Ductus Arteriosus, Patent; Echocardiography; Enterocolitis, Necrotizing;

2023

Other Studies

3 other studies available for ibuprofen and Infant, Newborn, Diseases

ArticleYear
Does Early Neonatal Thrombocytopenia Affect Ductal Therapeutic Response to Acetaminophen in Preterm Neonates?
    American journal of perinatology, 2022, Volume: 29, Issue:14

    Topics: Acetaminophen; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Infant, Newb

2022
Efficacy of Repeated Courses of Ibuprofen in the Closure of Patent Ductus Arteriosus in Premature Infants.
    Pediatrics and neonatology, 2017, Volume: 58, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Human

2017
Improved survival in the suckling rat model of group B streptococcal sepsis after treatment with nonsteroidal anti-inflammatory drugs.
    Pediatrics, 1982, Volume: 70, Issue:3

    Topics: Animals; Animals, Newborn; Disease Models, Animal; Humans; Ibuprofen; Indomethacin; Infant, Newborn;

1982