ibuprofen has been researched along with Hypoxia-Ischemia, Brain in 4 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study does not explain whether our intervention was not effective in blocking free radicals and inflammatory cytokines, if the dosing and route of administration were inadequate, or if other mediators existed that could have a more powerful role in brain injury during hypoxia-ischemia." | 2.74 | Ascorbic acid combined with ibuprofen in hypoxic ischemic encephalopathy: a randomized controlled trial. ( Aaref, M; Abd-Rabboh, L; Abdelrahman, S; Aly, H; El-Dib, M; Elsayed, A; Hassan, H; Nawwar, F, 2009) |
| "Ibuprofen treatment prevented the P3 HI-induced reductions in brain serotonin levels, serotonin transporter expression, and numbers of serotonergic neurons in the dorsal raphé nuclei on P10." | 1.38 | Post-insult ibuprofen treatment attenuates damage to the serotonergic system after hypoxia-ischemia in the immature rat brain. ( Buller, KM; Reinebrant, HE; Wixey, JA, 2012) |
| "Ibuprofen treatment also prevented the HI-induced loss O4- and O1-positive oligodendrocyte progenitor cells and myelin basic protein (MBP)-positive myelin content one week after P3 HI." | 1.37 | Ibuprofen inhibits neuroinflammation and attenuates white matter damage following hypoxia-ischemia in the immature rodent brain. ( Buller, KM; Carty, ML; Colditz, PB; Gobe, G; Reinebrant, HE; Wixey, JA, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Siskou, IC | 1 |
| Rekka, EA | 1 |
| Kourounakis, AP | 1 |
| Chrysselis, MC | 1 |
| Tsiakitzis, K | 1 |
| Kourounakis, PN | 1 |
| Aly, H | 1 |
| Abd-Rabboh, L | 1 |
| El-Dib, M | 1 |
| Nawwar, F | 1 |
| Hassan, H | 1 |
| Aaref, M | 1 |
| Abdelrahman, S | 1 |
| Elsayed, A | 1 |
| Carty, ML | 1 |
| Wixey, JA | 2 |
| Reinebrant, HE | 2 |
| Gobe, G | 1 |
| Colditz, PB | 1 |
| Buller, KM | 2 |
1 trial available for ibuprofen and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Ascorbic acid combined with ibuprofen in hypoxic ischemic encephalopathy: a randomized controlled trial.
Topics: Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Asphyxia Neonatorum; Developmental Disabiliti | 2009 |
3 other studies available for ibuprofen and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Design and study of some novel ibuprofen derivatives with potential nootropic and neuroprotective properties.
Topics: Animals; Antioxidants; Arthritis, Experimental; Biphenyl Compounds; Blood-Brain Barrier; Cholesterol | 2007 |
Ibuprofen inhibits neuroinflammation and attenuates white matter damage following hypoxia-ischemia in the immature rodent brain.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Encephalitis; Humans; Hypoxia-Ischemia, Brain; Ib | 2011 |
Post-insult ibuprofen treatment attenuates damage to the serotonergic system after hypoxia-ischemia in the immature rat brain.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Brain; Brain Injuries; Calcium-B | 2012 |