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ibuprofen and Hemorrhage, Peptic Ulcer

ibuprofen has been researched along with Hemorrhage, Peptic Ulcer in 12 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Research Excerpts

ExcerptRelevanceReference
"We analysed pooled data from two identical double-blind, randomized, 12-week endoscopy studies which compared the gastroduodenal toxicity of placebo (n=371), rofecoxib 25 mg (n=390), rofecoxib 50 mg (n=379), and ibuprofen 2400 mg daily (n=376) in patients with osteoarthritis."5.09Influence of risk factors on endoscopic and clinical ulcers in patients taking rofecoxib or ibuprofen in two randomized controlled trials. ( Bolognese, JA; Harper, SE; Hawkey, CJ; Laine, L; Mortensen, E; Quan, HU, 2001)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's2 (16.67)18.2507
2000's3 (25.00)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fukushima, E1
Monoi, N1
Mikoshiba, S1
Hirayama, Y1
Serizawa, T1
Adachi, K1
Koide, M1
Ohdera, M1
Murakoshi, M1
Kato, H1
Caunedo-Alvarez, A1
Gómez-Rodríguez, BJ1
Romero-Vázquez, J1
Argüelles-Arias, F1
Romero-Castro, R1
García-Montes, JM1
Pellicer-Bautista, FJ1
Herrerías-Gutiérrez, JM1
Shostak, NA1
Riabkova, AA1
Savel'ev, VS1
Maliarova, LP1
Pilotto, A1
Seripa, D1
Franceschi, M1
Scarcelli, C1
Colaizzo, D1
Grandone, E1
Niro, V1
Andriulli, A1
Leandro, G1
Di Mario, F1
Dallapiccola, B1
Diamantis, W1
Melton, J1
Sofia, RD1
Ciofalo, VB1
Bunton, RW1
Barrett, DC1
Palmer, DG1
Hamdy, RC1
Moore, SW1
Micklewright, M1
Beecham, VF1
Hawkey, CJ1
Laine, L1
Harper, SE1
Quan, HU1
Bolognese, JA1
Mortensen, E1
Engbaek, J1
Skriabin, ON1
Baranchuk, VN1
Manyshev, VG1
Kurygin, AA1
Somerville, K1
Faulkner, G1
Langman, M1
Johnson, JH1
Jick, H1
Hunter, JR1
Dickson, JF1

Trials

1 trial available for ibuprofen and Hemorrhage, Peptic Ulcer

ArticleYear
Influence of risk factors on endoscopic and clinical ulcers in patients taking rofecoxib or ibuprofen in two randomized controlled trials.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:10

    Topics: Aged; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method;

2001

Other Studies

11 other studies available for ibuprofen and Hemorrhage, Peptic Ulcer

ArticleYear
Protective effects of acetaminophen on ibuprofen-induced gastric mucosal damage in rats with associated suppression of matrix metalloproteinase.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 349, Issue:1

    Topics: Acetaminophen; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Do

2014
Macroscopic small bowel mucosal injury caused by chronic nonsteroidal anti-inflammatory drugs (NSAID) use as assessed by capsule endoscopy.
    Revista espanola de enfermedades digestivas, 2010, Volume: 102, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Capsule Endoscopy; Cyclooxygenase 2 Inhibitors

2010
[Gastrointestinal hemorrhages as complications of gastropathies associated with intake of nonsteroidal anti-inflammatory drugs].
    Terapevticheskii arkhiv, 2003, Volume: 75, Issue:5

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Duodenal Ulcer; Duodeno

2003
Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: role of cytochrome P450 2C9 polymorphisms.
    Gastroenterology, 2007, Volume: 133, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Cas

2007
Comparative gastric ulcerogenic effects of meseclazone, 5-chlorosalicylic acid and other nonsteroidal anti-inflammatory drugs following acute and repeated oral administration to rats.
    Toxicology and applied pharmacology, 1980, Mar-15, Volume: 52, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Benzoxazines; Biotransformation; Fenoprofen; Ibuprofen; Indometha

1980
Reintroduction of anti-inflammatory drug therapy after drug-associated gastro-intestinal disturbances.
    The New Zealand medical journal, 1982, Aug-25, Volume: 95, Issue:714

    Topics: Administration, Oral; Aged; Anti-Inflammatory Agents; Arthritis; Duodenal Ulcer; Female; Gastrointes

1982
When Goody's Powder is not so good.
    Journal of the Tennessee Medical Association, 1996, Volume: 89, Issue:2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Heart Failure; Humans; Ibuprofen; Knee Joint; Male; N

1996
[Gastrointestinal hemorrhage during treatment with ibuprofen (Brufen)].
    Ugeskrift for laeger, 1977, Feb-14, Volume: 139, Issue:7

    Topics: Aged; Aspirin; Drug Interactions; Female; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Male; Midd

1977
[The results of the endoscopic diathermy coagulation of hemorrhaging gastroduodenal ulcers].
    Khirurgiia, 1992, Issue:2

    Topics: Acute Disease; Duodenal Ulcer; Electrocoagulation; Female; Hemostasis, Endoscopic; Humans; Ibuprofen

1992
Non-steroidal anti-inflammatory drugs and bleeding peptic ulcer.
    Lancet (London, England), 1986, Mar-01, Volume: 1, Issue:8479

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Duodenal Ulcer; Female; Humans; Ibuprofen; Indome

1986
A followup study of ibuprofen users.
    The Journal of rheumatology, 1985, Volume: 12, Issue:3

    Topics: Adult; Agranulocytosis; Erythema Multiforme; Female; Gastritis; Hematemesis; Humans; Ibuprofen; Male

1985